High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 481 | 100 | | 7950 | 9207 | 278.6 | 129.42 | 10.26 | 12.06 | 144 | 163 | 187 | 215 | 241 | 273 | 314 | 413 | 495 | 0.0924 | 851 | 0.695 | 94.53 | 15.03 | 6 | 0.0267 | 212 | 0.0018 | 9.35 | 6.724 | 0.3596 | 94338.5 | 37400000 | 16500000000 | 7810000000000 | 0.4212 | 0.2162 | 0.0009 | 0.0016 | 0.0013 | 0.0016 | 0.0068 | 0.0043 | 0.0175 | 0.0086 | 0.0554 | 0.0374 | 0.0967 | 0.0491 | 0.0797 | 0.0423 | 0.1121 | 0.0623 | 0.6297 | 0.7930 | 0.0004 | 0.0011 | 0.0007 | 0.0010 | 0.0027 | 0.0027 | 0.0064 | 0.0047 | 0.0202 | 0.0199 | 0.0282 | 0.0236 | 0.0285 | 0.0216 | 0.0407 | 0.0308 | 0.8721 | 0.8946 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0028 | 0.0017 | 0.0070 | 0.0091 | 0.0167 | 0.0205 | 0.0423 | 0.0400 | 0.0265 | 0.0377 | 0.0307 | 0.0354 | 0.8721 | 0.8556 | 0.0010 | 0.0016 | 0.0049 | 0.0092 | 0.0191 | 0.0384 | 0.0309 | 0.0427 | 0.8521 | 3 | 5 | 5 | 6 | 7 | 8 | 9 | 11 | 19 | 0.1322 | 0.45 | 1.509 | 0.5124 | 250.6 | 12213 | 813301 | 62700000 | 0.5153 | 0.1526 | 0.0886 | 0.0079 | 0.2162 | 0.0407 | 0.2503 | 0.0797 | 0.2088 | 0.1421 | 0.1362 | 0.1824 | 0.0696 | 0.1959 | 0.0225 | 0.1743 | 0.0078 | 0.1275 | 0.0000 | 0.0493 | 0.0425 | 0.0045 | 0.1012 | 0.0274 | 0.1320 | 0.0540 | 0.1129 | 0.0995 | 0.0975 | 0.1431 | 0.0935 | 0.1554 | 0.0649 | 0.1304 | 0.0728 | 0.1196 | 0.2827 | 0.2662 | 0.0790 | 0.0376 | 0.0515 | 0.0295 | 0.0334 | 0.0302 | 0.0322 | 0.0376 | 0.0632 | 0.0604 | 0.0971 | 0.1150 | 0.0872 | 0.0825 | 0.0989 | 0.1098 | 0.4576 | 0.4974 | 0.1005 | 0.0895 | 0.0781 | 0.0561 | 0.0570 | 0.0875 | 0.0557 | 0.0858 | 0.3897 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 469 | 396 | | 3985 | 3374 | 160.1 | 46.65 | 190.25 | 141.76 | 107 | 121 | 132 | 142 | 153 | 165 | 177 | 195 | 221 | 0.2110 | 712 | 0.988 | 83.24 | 28.02 | 1 | 0.0575 | 229 | 0.0012 | 50.08 | 6.991 | 0.1783 | 27806.5 | 5240000 | 1070000000 | 235000000000 | 0.4379 | 0.2135 | 0.0010 | 0.0000 | 0.0005 | 0.0000 | 0.0144 | 0.0017 | 0.0460 | 0.0032 | 0.1321 | 0.0326 | 0.1991 | 0.0843 | 0.1709 | 0.0837 | 0.1728 | 0.1160 | 0.2633 | 0.6784 | 0.0007 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0003 | 0.0098 | 0.0016 | 0.0480 | 0.0199 | 0.0912 | 0.0482 | 0.0784 | 0.0364 | 0.0966 | 0.0566 | 0.6743 | 0.8371 | 0.0069 | 0.0079 | 0.0023 | 0.0237 | 0.0230 | 0.0211 | 0.0746 | 0.0868 | 0.1389 | 0.2237 | 0.1929 | 0.2053 | 0.1114 | 0.0974 | 0.1389 | 0.1316 | 0.3111 | 0.2026 | 0.0017 | 0.0017 | 0.0067 | 0.0274 | 0.1016 | 0.1496 | 0.1111 | 0.1407 | 0.4595 | 58 | 75 | 93 | 117 | 144 | 179 | 227 | 297 | 404 | 0.0022 | 69.15 | 6.693 | 0.2400 | 56286.8 | 22200000 | 10500000000 | 5560000000000 | 0.5618 | 0.1030 | 0.0253 | 0.0040 | 0.1149 | 0.0127 | 0.2821 | 0.0573 | 0.1909 | 0.1131 | 0.1740 | 0.1863 | 0.1166 | 0.2126 | 0.0439 | 0.1242 | 0.0389 | 0.1449 | 0.0135 | 0.1449 | 0.0006 | 0.0019 | 0.0025 | 0.0029 | 0.0125 | 0.0058 | 0.0368 | 0.0277 | 0.1085 | 0.0893 | 0.1696 | 0.1422 | 0.1103 | 0.1053 | 0.1490 | 0.1465 | 0.4102 | 0.4784 | 0.0049 | 0.0037 | 0.0069 | 0.0075 | 0.0208 | 0.0298 | 0.0573 | 0.0658 | 0.1285 | 0.1466 | 0.1887 | 0.1814 | 0.1176 | 0.1379 | 0.1542 | 0.1466 | 0.3211 | 0.2807 | 0.0016 | 0.0071 | 0.0158 | 0.0434 | 0.1278 | 0.1838 | 0.1112 | 0.1546 | 0.3549 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1203 | 196 | | 3608 | 1256 | 112.8 | 33.02 | 56.49 | 42.34 | 79 | 87 | 93 | 99 | 105 | 112 | 122 | 134 | 156 | 0.4076 | 512 | 0.975 | 95.35 | 33.06 | 2 | 0.0734 | 265 | 0.0032 | 16.99 | 6.143 | 0.2879 | 13822.0 | 1860000 | 276000000 | 45100000000 | 0.3979 | 0.2576 | 0.0010 | 0.0003 | 0.0065 | 0.0006 | 0.0176 | 0.0028 | 0.0391 | 0.0056 | 0.0918 | 0.0314 | 0.1565 | 0.0637 | 0.1590 | 0.0566 | 0.1951 | 0.0942 | 0.3335 | 0.7448 | 0.0004 | 0.0000 | 0.0026 | 0.0000 | 0.0097 | 0.0008 | 0.0164 | 0.0025 | 0.0421 | 0.0200 | 0.0742 | 0.0382 | 0.0753 | 0.0306 | 0.1037 | 0.0514 | 0.6755 | 0.8564 | 0.0102 | 0.0029 | 0.0116 | 0.0117 | 0.0277 | 0.0264 | 0.0524 | 0.0733 | 0.1252 | 0.1554 | 0.1514 | 0.1525 | 0.1208 | 0.1202 | 0.1339 | 0.1320 | 0.3668 | 0.3255 | 0.0035 | 0.0085 | 0.0148 | 0.0318 | 0.0890 | 0.1329 | 0.1025 | 0.1576 | 0.4594 | 20 | 26 | 31 | 37 | 45 | 55 | 65 | 79 | 102 | 0.0171 | 7.89 | 4.661 | 0.4707 | 4982.0 | 681992 | 133000000 | 33000000000 | 0.5597 | 0.0948 | 0.0435 | 0.0159 | 0.1268 | 0.0336 | 0.1739 | 0.0814 | 0.1775 | 0.1310 | 0.1920 | 0.1717 | 0.1522 | 0.1664 | 0.0942 | 0.1451 | 0.0254 | 0.1469 | 0.0145 | 0.1080 | 0.0016 | 0.0073 | 0.0126 | 0.0085 | 0.0316 | 0.0208 | 0.0411 | 0.0403 | 0.1785 | 0.1404 | 0.2054 | 0.2088 | 0.1627 | 0.1416 | 0.1769 | 0.1844 | 0.1896 | 0.2479 | 0.0056 | 0.0197 | 0.0364 | 0.0630 | 0.0756 | 0.0709 | 0.1064 | 0.1102 | 0.2269 | 0.2283 | 0.1961 | 0.1811 | 0.1064 | 0.1457 | 0.1457 | 0.1220 | 0.1008 | 0.0591 | 0.0021 | 0.0123 | 0.0452 | 0.0903 | 0.2074 | 0.2177 | 0.1561 | 0.1335 | 0.1355 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1235 | 928 | | 3908 | 866 | 131.6 | 35.52 | 83.99 | 75.24 | 92 | 104 | 113 | 120 | 128 | 134 | 143 | 154 | 171 | 0.5855 | 507 | 1.261 | 98.62 | 31.32 | 1 | 0.0581 | 227 | 0.0023 | 24.71 | 6.369 | 0.2431 | 18576.3 | 2850000 | 480000000 | 90700000000 | 0.4962 | 0.1800 | 0.0025 | 0.0000 | 0.0025 | 0.0003 | 0.0091 | 0.0020 | 0.0313 | 0.0045 | 0.0844 | 0.0247 | 0.1671 | 0.0656 | 0.1560 | 0.0617 | 0.1844 | 0.1041 | 0.3627 | 0.7372 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0016 | 0.0107 | 0.0024 | 0.0488 | 0.0200 | 0.0837 | 0.0431 | 0.0755 | 0.0318 | 0.1153 | 0.0568 | 0.6620 | 0.8442 | 0.0109 | 0.0207 | 0.0125 | 0.0290 | 0.0498 | 0.0290 | 0.0888 | 0.1079 | 0.1495 | 0.1992 | 0.1947 | 0.1826 | 0.1137 | 0.0747 | 0.1340 | 0.1452 | 0.2461 | 0.2116 | 0.0012 | 0.0075 | 0.0184 | 0.0519 | 0.1308 | 0.1360 | 0.1314 | 0.1527 | 0.3700 | 16 | 24 | 36 | 50 | 62 | 79 | 105 | 130 | 176 | 0.0070 | 32.32 | 5.471 | 0.3545 | 12708.8 | 3020000 | 1050000000 | 473000000000 | 0.5943 | 0.0759 | 0.0880 | 0.0099 | 0.2240 | 0.0627 | 0.2160 | 0.0924 | 0.2480 | 0.1881 | 0.1600 | 0.2277 | 0.0560 | 0.2376 | 0.0080 | 0.0792 | 0.0000 | 0.0528 | 0.0000 | 0.0495 | 0.0150 | 0.0019 | 0.0200 | 0.0174 | 0.0324 | 0.0174 | 0.0549 | 0.0581 | 0.2893 | 0.2364 | 0.3566 | 0.3682 | 0.1322 | 0.1492 | 0.0574 | 0.0717 | 0.0424 | 0.0795 | 0.0072 | 0.0047 | 0.0217 | 0.0235 | 0.0580 | 0.0798 | 0.1051 | 0.1221 | 0.2754 | 0.2864 | 0.3370 | 0.3146 | 0.1123 | 0.0986 | 0.0507 | 0.0376 | 0.0326 | 0.0329 | 0.0151 | 0.0151 | 0.0272 | 0.1057 | 0.2779 | 0.3595 | 0.1178 | 0.0453 | 0.0363 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 365 | 353 | | 5969 | 9686 | 532.6 | 131.58 | 28.76 | 57.02 | 329 | 402 | 483 | 536 | 572 | 597 | 619 | 644 | 676 | 0.0840 | 814 | 1.039 | 109.33 | 39.70 | 3 | 0.0476 | 284 | 0.0007 | 61.44 | 7.562 | 0.1890 | 300963.0 | 177000000 | 107000000000 | 65900000000000 | 0.4153 | 0.2188 | 0.0006 | 0.0000 | 0.0018 | 0.0000 | 0.0036 | 0.0002 | 0.0109 | 0.0011 | 0.0555 | 0.0200 | 0.0772 | 0.0344 | 0.0832 | 0.0215 | 0.1212 | 0.0340 | 0.6460 | 0.8888 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0015 | 0.0011 | 0.0246 | 0.0200 | 0.0316 | 0.0336 | 0.0250 | 0.0204 | 0.0396 | 0.0310 | 0.8774 | 0.8937 | 0.0055 | 0.0000 | 0.0071 | 0.0000 | 0.0188 | 1.0000 | 0.0290 | 0.0000 | 0.0565 | 0.0000 | 0.0863 | 0.0000 | 0.0847 | 0.0000 | 0.1145 | 0.0000 | 0.5976 | 0.0000 | 0.0003 | 0.0000 | 0.0019 | 0.0047 | 0.0314 | 0.0394 | 0.0411 | 0.0607 | 0.8205 | 8 | 10 | 11 | 13 | 16 | 21 | 27 | 36 | 51 | 0.1769 | 0.75 | 1.769 | 0.6861 | 4078.2 | 2130000 | 1520000000 | 1200000000000 | 0.5279 | 0.1420 | 0.0341 | 0.0214 | 0.0384 | 0.0239 | 0.0803 | 0.0306 | 0.0852 | 0.0415 | 0.1165 | 0.0580 | 0.1541 | 0.0685 | 0.1925 | 0.0928 | 0.1996 | 0.1557 | 0.0994 | 0.5076 | 0.0086 | 0.0112 | 0.0106 | 0.0098 | 0.0185 | 0.0121 | 0.0222 | 0.0179 | 0.0376 | 0.0331 | 0.0539 | 0.0414 | 0.0587 | 0.0485 | 0.0952 | 0.0713 | 0.6946 | 0.7548 | 0.0124 | 0.0117 | 0.0133 | 0.0123 | 0.0143 | 0.0178 | 0.0219 | 0.0270 | 0.0505 | 0.0596 | 0.0657 | 0.0713 | 0.0634 | 0.0774 | 0.0991 | 0.1167 | 0.6594 | 0.6063 | 0.0141 | 0.0137 | 0.0213 | 0.0260 | 0.0416 | 0.0513 | 0.0604 | 0.0853 | 0.6863 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 797 | 276 | | 3081 | 14857 | 257.1 | 73.60 | 95.99 | 124.19 | 175 | 187 | 202 | 218 | 241 | 266 | 296 | 325 | 367 | 0.0703 | 1045 | 0.709 | 60.54 | 16.03 | 2 | 0.0568 | 175 | 0.0097 | 3.01 | 5.047 | 0.5308 | 71538.3 | 21500000 | 6880000000 | 2330000000000 | 0.3683 | 0.2682 | 0.0023 | 0.0000 | 0.0053 | 0.0000 | 0.0107 | 0.0015 | 0.0328 | 0.0041 | 0.0710 | 0.0354 | 0.1154 | 0.0479 | 0.1054 | 0.0420 | 0.1398 | 0.0593 | 0.5172 | 0.8099 | 0.0014 | 0.0000 | 0.0019 | 0.0000 | 0.0043 | 0.0007 | 0.0125 | 0.0013 | 0.0288 | 0.0202 | 0.0389 | 0.0276 | 0.0408 | 0.0189 | 0.0504 | 0.0315 | 0.8209 | 0.8998 | 0.0013 | 0.0000 | 0.0000 | 0.0111 | 0.0090 | 0.0028 | 0.0168 | 0.0306 | 0.0530 | 0.0889 | 0.0917 | 0.1306 | 0.0646 | 0.1139 | 0.0904 | 0.1500 | 0.6731 | 0.4722 | 0.0015 | 0.0015 | 0.0052 | 0.0126 | 0.0238 | 0.0535 | 0.0416 | 0.0558 | 0.8045 | 12 | 19 | 29 | 42 | 54 | 70 | 95 | 135 | 230 | 0.0663 | 4.54 | 3.869 | 0.7237 | 24635.6 | 11400000 | 7270000000 | 5520000000000 | 0.4425 | 0.1810 | 0.0092 | 0.0039 | 0.0252 | 0.0102 | 0.0406 | 0.0158 | 0.0729 | 0.0304 | 0.1237 | 0.0621 | 0.1566 | 0.0900 | 0.1494 | 0.0954 | 0.1869 | 0.1280 | 0.2356 | 0.5641 | 0.0025 | 0.0017 | 0.0033 | 0.0049 | 0.0040 | 0.0052 | 0.0113 | 0.0100 | 0.0302 | 0.0240 | 0.0458 | 0.0344 | 0.0473 | 0.0408 | 0.0691 | 0.0611 | 0.7864 | 0.8179 | 0.0008 | 0.0007 | 0.0034 | 0.0027 | 0.0059 | 0.0050 | 0.0163 | 0.0174 | 0.0487 | 0.0557 | 0.0704 | 0.0795 | 0.0637 | 0.0651 | 0.0789 | 0.0849 | 0.7118 | 0.6890 | 0.0011 | 0.0052 | 0.0059 | 0.0142 | 0.0363 | 0.0542 | 0.0582 | 0.0716 | 0.7533 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1132 | 783 | | 5806 | 15602 | 539.4 | 203.19 | 87.63 | 159.39 | 237 | 320 | 418 | 529 | 593 | 630 | 664 | 708 | 771 | 0.0657 | 1025 | 0.615 | 160.90 | 32.02 | 5 | 0.0725 | 421 | 0.0005 | 70.80 | 7.812 | 0.1691 | 332268.0 | 221000000 | 155000000000 | 113000000000000 | 0.4107 | 0.2133 | 0.0000 | 0.0000 | 0.0015 | 0.0005 | 0.0067 | 0.0003 | 0.0370 | 0.0061 | 0.1090 | 0.0389 | 0.1697 | 0.0718 | 0.1398 | 0.0509 | 0.1506 | 0.0799 | 0.3856 | 0.7517 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0013 | 0.0213 | 0.0203 | 0.0424 | 0.0428 | 0.0263 | 0.0197 | 0.0354 | 0.0324 | 0.8711 | 0.8834 | 0.0015 | 0.0000 | 0.0078 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0000 | 0.0553 | 0.0000 | 0.0852 | 0.0000 | 0.0715 | 0.0000 | 0.0832 | 0.0000 | 0.6681 | 1.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0038 | 0.0262 | 0.0487 | 0.0324 | 0.0461 | 0.8422 | 6 | 8 | 9 | 11 | 14 | 23 | 51 | 120 | 297 | 0.1136 | 5.25 | 3.423 | 0.5908 | 33081.1 | 18000000 | 11400000000 | 7790000000000 | 0.5377 | 0.1183 | 0.0619 | 0.0026 | 0.1417 | 0.0166 | 0.2366 | 0.0806 | 0.1761 | 0.1157 | 0.1747 | 0.1905 | 0.0894 | 0.2027 | 0.0688 | 0.1381 | 0.0303 | 0.1234 | 0.0206 | 0.1298 | 0.0010 | 0.0002 | 0.0007 | 0.0002 | 0.0020 | 0.0017 | 0.0110 | 0.0119 | 0.0483 | 0.0430 | 0.0841 | 0.0733 | 0.0507 | 0.0497 | 0.0741 | 0.0696 | 0.7281 | 0.7502 | 0.0003 | 0.0007 | 0.0012 | 0.0036 | 0.0056 | 0.0029 | 0.0148 | 0.0180 | 0.0545 | 0.0546 | 0.0898 | 0.0971 | 0.0634 | 0.0605 | 0.0756 | 0.0840 | 0.6947 | 0.6788 | 0.0003 | 0.0005 | 0.0038 | 0.0110 | 0.0513 | 0.0880 | 0.0548 | 0.0784 | 0.7120 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 331 | 718 | | 6517 | 14109 | 121.3 | 38.02 | 212.08 | 139.30 | 76 | 89 | 98 | 106 | 116 | 126 | 139 | 154 | 173 | 0.0670 | 946 | 0.522 | 141.32 | 34.66 | 1 | 0.0758 | 494 | 0.0017 | 23.72 | 6.654 | 0.2362 | 16163.3 | 2350000 | 371000000 | 63300000000 | 0.4672 | 0.1926 | 0.0013 | 0.0002 | 0.0033 | 0.0000 | 0.0140 | 0.0028 | 0.0447 | 0.0100 | 0.1142 | 0.0351 | 0.1883 | 0.0820 | 0.1596 | 0.0767 | 0.1756 | 0.1199 | 0.2990 | 0.6732 | 0.0004 | 0.0002 | 0.0017 | 0.0000 | 0.0041 | 0.0012 | 0.0137 | 0.0047 | 0.0345 | 0.0203 | 0.0687 | 0.0391 | 0.0668 | 0.0281 | 0.0852 | 0.0555 | 0.7248 | 0.8511 | 0.0006 | 0.0027 | 0.0019 | 0.0190 | 0.0131 | 0.0244 | 0.0473 | 0.0799 | 0.1021 | 0.1721 | 0.1594 | 0.2033 | 0.1152 | 0.1179 | 0.1519 | 0.1518 | 0.4085 | 0.2290 | 0.0014 | 0.0024 | 0.0106 | 0.0294 | 0.0608 | 0.1086 | 0.0820 | 0.1134 | 0.5914 | 42 | 83 | 121 | 156 | 193 | 231 | 273 | 329 | 409 | 0.0025 | 30.32 | 6.672 | 0.2808 | 64379.2 | 23700000 | 9980000000 | 4630000000000 | 0.5768 | 0.1249 | 0.0132 | 0.0007 | 0.0829 | 0.0038 | 0.2244 | 0.0304 | 0.2064 | 0.0794 | 0.1855 | 0.1514 | 0.1565 | 0.2137 | 0.0868 | 0.1808 | 0.0344 | 0.1635 | 0.0100 | 0.1763 | 0.0005 | 0.0000 | 0.0010 | 0.0005 | 0.0062 | 0.0022 | 0.0221 | 0.0124 | 0.0612 | 0.0460 | 0.1242 | 0.0904 | 0.0972 | 0.0798 | 0.1246 | 0.1106 | 0.5630 | 0.6581 | 0.0029 | 0.0020 | 0.0062 | 0.0061 | 0.0179 | 0.0276 | 0.0458 | 0.0711 | 0.1142 | 0.1294 | 0.1552 | 0.1673 | 0.1257 | 0.1207 | 0.1490 | 0.1595 | 0.3830 | 0.3164 | 0.0008 | 0.0041 | 0.0099 | 0.0341 | 0.0887 | 0.1328 | 0.1162 | 0.1460 | 0.4674 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 927 | 522 | | 3614 | 6289 | 297.5 | 144.28 | 59.44 | 77.60 | 127 | 157 | 192 | 233 | 266 | 305 | 406 | 465 | 511 | 0.1040 | 654 | 1.229 | 109.25 | 47.52 | 2 | 0.0819 | 296 | 0.0028 | 6.07 | 6.131 | 0.4083 | 109347.0 | 45800000 | 20700000000 | 9820000000000 | 0.3640 | 0.2549 | 0.0012 | 0.0000 | 0.0012 | 0.0006 | 0.0036 | 0.0025 | 0.0324 | 0.0086 | 0.1032 | 0.0531 | 0.1429 | 0.0834 | 0.1273 | 0.0562 | 0.1020 | 0.0828 | 0.4862 | 0.7128 | 0.0005 | 0.0000 | 0.0005 | 0.0004 | 0.0005 | 0.0015 | 0.0076 | 0.0030 | 0.0219 | 0.0203 | 0.0343 | 0.0263 | 0.0281 | 0.0192 | 0.0357 | 0.0312 | 0.8710 | 0.8980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0039 | 0.0331 | 0.0347 | 0.0410 | 0.0597 | 0.0316 | 0.0414 | 0.0458 | 0.0462 | 0.8469 | 0.8141 | 0.0020 | 0.0013 | 0.0027 | 0.0054 | 0.0229 | 0.0404 | 0.0242 | 0.0310 | 0.8700 | 8 | 11 | 14 | 19 | 26 | 38 | 58 | 92 | 162 | 0.0962 | 2.42 | 3.459 | 0.6933 | 9553.8 | 2410000 | 755000000 | 271000000000 | 0.5400 | 0.1318 | 0.0018 | 0.0033 | 0.0126 | 0.0122 | 0.0650 | 0.0236 | 0.1733 | 0.0447 | 0.2365 | 0.0943 | 0.2166 | 0.1561 | 0.1480 | 0.1423 | 0.1137 | 0.1740 | 0.0325 | 0.3496 | 0.0000 | 0.0015 | 0.0005 | 0.0034 | 0.0032 | 0.0076 | 0.0142 | 0.0125 | 0.0500 | 0.0386 | 0.0866 | 0.0773 | 0.0596 | 0.0583 | 0.0830 | 0.0735 | 0.7030 | 0.7273 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0037 | 0.0064 | 0.0197 | 0.0227 | 0.0614 | 0.0716 | 0.1020 | 0.1106 | 0.0694 | 0.0738 | 0.0860 | 0.0865 | 0.6566 | 0.6270 | 0.0011 | 0.0027 | 0.0043 | 0.0160 | 0.0543 | 0.1005 | 0.0660 | 0.0787 | 0.6766 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 931 | 115 | | 3279 | 6983 | 116.8 | 25.16 | 91.19 | 65.40 | 87 | 94 | 101 | 107 | 114 | 121 | 129 | 138 | 151 | 0.0971 | 678 | 0.521 | 85.63 | 18.00 | 1 | 0.0753 | 247 | 0.0015 | 34.98 | 6.738 | 0.2061 | 14263.7 | 1820000 | 243000000 | 33600000000 | 0.4567 | 0.1958 | 0.0015 | 0.0000 | 0.0044 | 0.0000 | 0.0174 | 0.0003 | 0.0377 | 0.0055 | 0.0856 | 0.0281 | 0.1393 | 0.0445 | 0.1581 | 0.0448 | 0.1978 | 0.0726 | 0.3583 | 0.8042 | 0.0011 | 0.0000 | 0.0026 | 0.0000 | 0.0049 | 0.0003 | 0.0098 | 0.0003 | 0.0448 | 0.0203 | 0.0726 | 0.0276 | 0.0704 | 0.0218 | 0.1099 | 0.0470 | 0.6839 | 0.8827 | 0.0068 | 0.0000 | 0.0102 | 0.0382 | 0.0441 | 0.0892 | 0.0849 | 0.1401 | 0.1494 | 0.2038 | 0.1511 | 0.1975 | 0.1324 | 0.1592 | 0.1647 | 0.0701 | 0.2564 | 0.1019 | 0.0026 | 0.0072 | 0.0132 | 0.0349 | 0.0829 | 0.1250 | 0.0980 | 0.1342 | 0.5020 | 26 | 35 | 46 | 59 | 74 | 91 | 112 | 140 | 183 | 0.0140 | 7.49 | 5.001 | 0.4623 | 12591.6 | 2290000 | 504000000 | 127000000000 | 0.5517 | 0.1402 | 0.0219 | 0.0015 | 0.1015 | 0.0080 | 0.1790 | 0.0298 | 0.2075 | 0.0795 | 0.2009 | 0.1677 | 0.1286 | 0.2109 | 0.0825 | 0.1702 | 0.0475 | 0.1583 | 0.0307 | 0.1742 | 0.0011 | 0.0005 | 0.0025 | 0.0032 | 0.0070 | 0.0029 | 0.0242 | 0.0174 | 0.0752 | 0.0594 | 0.1144 | 0.0807 | 0.1014 | 0.0818 | 0.1355 | 0.1148 | 0.5386 | 0.6392 | 0.0009 | 0.0042 | 0.0060 | 0.0072 | 0.0133 | 0.0240 | 0.0486 | 0.0665 | 0.1298 | 0.1450 | 0.1660 | 0.1905 | 0.1243 | 0.1240 | 0.1596 | 0.1534 | 0.3517 | 0.2852 | 0.0021 | 0.0046 | 0.0099 | 0.0368 | 0.0916 | 0.1561 | 0.1164 | 0.1465 | 0.4360 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 880 | 168 | | 38955 | 26240 | 163.7 | 54.42 | 189.84 | 155.38 | 92 | 114 | 132 | 148 | 164 | 179 | 194 | 210 | 233 | 0.1215 | 3188 | 0.799 | 74.95 | 17.03 | 13 | 0.0043 | 168 | 0.0008 | 32.80 | 7.366 | 0.2060 | 29769.9 | 5880000 | 1240000000 | 280000000000 | 0.5763 | 0.1150 | 0.0010 | 0.0002 | 0.0035 | 0.0005 | 0.0154 | 0.0020 | 0.0472 | 0.0094 | 0.1113 | 0.0378 | 0.1741 | 0.0717 | 0.1653 | 0.0787 | 0.1782 | 0.1069 | 0.3041 | 0.6929 | 0.0003 | 0.0001 | 0.0009 | 0.0002 | 0.0030 | 0.0009 | 0.0108 | 0.0048 | 0.0303 | 0.0203 | 0.0519 | 0.0341 | 0.0512 | 0.0327 | 0.0704 | 0.0446 | 0.7812 | 0.8624 | 0.0018 | 0.0076 | 0.0072 | 0.0135 | 0.0124 | 0.0327 | 0.0413 | 0.0819 | 0.0859 | 0.1325 | 0.1267 | 0.1726 | 0.1108 | 0.1197 | 0.1380 | 0.1307 | 0.4759 | 0.3088 | 0.0012 | 0.0016 | 0.0058 | 0.0209 | 0.0477 | 0.0807 | 0.0801 | 0.1009 | 0.6610 | 30 | 51 | 77 | 110 | 148 | 191 | 245 | 316 | 419 | 0.0043 | 23.31 | 6.446 | 0.3390 | 60178.8 | 24700000 | 11900000000 | 6310000000000 | 0.6103 | 0.0987 | 0.0154 | 0.0035 | 0.0720 | 0.0118 | 0.1491 | 0.0312 | 0.1825 | 0.0787 | 0.1846 | 0.1419 | 0.1799 | 0.1989 | 0.0982 | 0.1547 | 0.0673 | 0.1582 | 0.0509 | 0.2210 | 0.0009 | 0.0008 | 0.0043 | 0.0023 | 0.0067 | 0.0044 | 0.0211 | 0.0165 | 0.0660 | 0.0589 | 0.1135 | 0.1002 | 0.0823 | 0.0792 | 0.1052 | 0.1029 | 0.6000 | 0.6347 | 0.0009 | 0.0028 | 0.0066 | 0.0068 | 0.0095 | 0.0154 | 0.0324 | 0.0388 | 0.0825 | 0.0887 | 0.1348 | 0.1364 | 0.0914 | 0.0993 | 0.1153 | 0.1173 | 0.5266 | 0.4944 | 0.0018 | 0.0040 | 0.0100 | 0.0258 | 0.0759 | 0.1202 | 0.0937 | 0.1112 | 0.5575 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 758 | 118 | | 3722 | 7678 | 368.8 | 182.51 | 164.24 | 272.94 | 145 | 178 | 217 | 266 | 351 | 446 | 510 | 563 | 614 | 0.0847 | 650 | 1.108 | 87.24 | 31.58 | 2 | 0.0623 | 232 | 0.0018 | 10.54 | 6.623 | 0.3115 | 169332.0 | 88000000 | 48900000000 | 28300000000000 | 0.2899 | 0.3386 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0086 | 0.0047 | 0.0310 | 0.0167 | 0.1480 | 0.0670 | 0.2220 | 0.0965 | 0.1463 | 0.0810 | 0.1911 | 0.1186 | 0.2530 | 0.6122 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0010 | 0.0020 | 0.0029 | 0.0035 | 0.0201 | 0.0203 | 0.0315 | 0.0250 | 0.0220 | 0.0238 | 0.0382 | 0.0355 | 0.8844 | 0.8892 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0066 | 0.0149 | 0.0238 | 0.0411 | 0.0416 | 0.0747 | 0.0350 | 0.0691 | 0.0430 | 0.0756 | 0.8500 | 0.7208 | 0.0000 | 0.0000 | 0.0006 | 0.0017 | 0.0251 | 0.0345 | 0.0239 | 0.0395 | 0.8747 | 12 | 17 | 22 | 28 | 43 | 72 | 114 | 240 | 499 | 0.0621 | 27.12 | 4.594 | 0.6002 | 101458.0 | 93500000 | 101000000000 | 118000000000000 | 0.3873 | 0.2579 | 0.0278 | 0.0021 | 0.0732 | 0.0103 | 0.1995 | 0.0372 | 0.1692 | 0.0702 | 0.1843 | 0.1569 | 0.1162 | 0.1610 | 0.0909 | 0.1352 | 0.0707 | 0.1197 | 0.0682 | 0.3075 | 0.0019 | 0.0000 | 0.0014 | 0.0028 | 0.0053 | 0.0035 | 0.0101 | 0.0102 | 0.0483 | 0.0501 | 0.0718 | 0.0654 | 0.0565 | 0.0556 | 0.0775 | 0.0832 | 0.7271 | 0.7292 | 0.0000 | 0.0006 | 0.0041 | 0.0006 | 0.0053 | 0.0026 | 0.0077 | 0.0057 | 0.0543 | 0.0529 | 0.0721 | 0.0861 | 0.0543 | 0.0529 | 0.0874 | 0.0848 | 0.7147 | 0.7136 | 0.0005 | 0.0027 | 0.0086 | 0.0065 | 0.0507 | 0.0706 | 0.0507 | 0.0841 | 0.7256 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 301 | 366 | | 6423 | 26442 | 283.5 | 88.59 | 136.46 | 161.23 | 181 | 203 | 226 | 250 | 273 | 298 | 324 | 354 | 403 | 0.0445 | 1176 | 1.048 | 155.22 | 58.08 | 2 | 0.0629 | 404 | 0.0011 | 32.72 | 7.058 | 0.2184 | 88205.5 | 29900000 | 10900000000 | 4280000000000 | 0.4253 | 0.2195 | 0.0007 | 0.0000 | 0.0034 | 0.0009 | 0.0146 | 0.0032 | 0.0409 | 0.0087 | 0.0940 | 0.0368 | 0.1492 | 0.0716 | 0.1359 | 0.0612 | 0.1683 | 0.0927 | 0.3931 | 0.7248 | 0.0002 | 0.0000 | 0.0009 | 0.0007 | 0.0040 | 0.0017 | 0.0105 | 0.0042 | 0.0296 | 0.0204 | 0.0525 | 0.0362 | 0.0423 | 0.0262 | 0.0710 | 0.0400 | 0.7891 | 0.8707 | 0.0013 | 0.0070 | 0.0064 | 0.0098 | 0.0135 | 0.0209 | 0.0411 | 0.0809 | 0.1046 | 0.1492 | 0.1380 | 0.1618 | 0.1014 | 0.1213 | 0.1444 | 0.1269 | 0.4493 | 0.3222 | 0.0000 | 0.0020 | 0.0040 | 0.0131 | 0.0529 | 0.0827 | 0.0844 | 0.1138 | 0.6471 | 9 | 14 | 24 | 38 | 66 | 107 | 167 | 252 | 373 | 0.0462 | 12.01 | 4.985 | 0.5301 | 44615.1 | 20200000 | 11100000000 | 6860000000000 | 0.4314 | 0.2136 | 0.0461 | 0.0018 | 0.1520 | 0.0172 | 0.2501 | 0.0918 | 0.1590 | 0.1281 | 0.1504 | 0.1891 | 0.1005 | 0.1767 | 0.0606 | 0.1214 | 0.0494 | 0.1181 | 0.0317 | 0.1558 | 0.0002 | 0.0002 | 0.0001 | 0.0004 | 0.0016 | 0.0014 | 0.0128 | 0.0100 | 0.0523 | 0.0437 | 0.0925 | 0.0734 | 0.0653 | 0.0565 | 0.0976 | 0.0819 | 0.6777 | 0.7324 | 0.0001 | 0.0006 | 0.0009 | 0.0013 | 0.0036 | 0.0042 | 0.0155 | 0.0196 | 0.0730 | 0.0822 | 0.1241 | 0.1392 | 0.0858 | 0.0894 | 0.1200 | 0.1337 | 0.5771 | 0.5298 | 0.0001 | 0.0005 | 0.0029 | 0.0149 | 0.0623 | 0.1047 | 0.0750 | 0.1099 | 0.6295 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 110 | 146 | | 3370 | 10890 | 147.0 | 47.54 | 205.95 | 210.52 | 96 | 109 | 120 | 130 | 141 | 152 | 166 | 184 | 210 | 0.0687 | 748 | 0.698 | 87.82 | 16.12 | 1 | 0.0591 | 199 | 0.0013 | 45.70 | 6.937 | 0.1972 | 23872.7 | 4240000 | 821000000 | 172000000000 | 0.4754 | 0.1834 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0213 | 0.0022 | 0.0640 | 0.0076 | 0.1469 | 0.0404 | 0.2133 | 0.0913 | 0.1633 | 0.0822 | 0.1664 | 0.1230 | 0.2176 | 0.6533 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0021 | 0.0003 | 0.0144 | 0.0026 | 0.0499 | 0.0204 | 0.0960 | 0.0459 | 0.0828 | 0.0328 | 0.1240 | 0.0548 | 0.6288 | 0.8431 | 0.0013 | 0.0000 | 0.0038 | 0.0233 | 0.0115 | 0.0465 | 0.0712 | 0.0930 | 0.1387 | 0.1964 | 0.2010 | 0.1783 | 0.1221 | 0.1163 | 0.1425 | 0.1370 | 0.3079 | 0.2093 | 0.0000 | 0.0026 | 0.0073 | 0.0389 | 0.0956 | 0.1404 | 0.1107 | 0.1325 | 0.4720 | 20 | 29 | 54 | 89 | 136 | 193 | 264 | 354 | 501 | 0.0118 | 65.86 | 6.461 | 0.3264 | 86732.2 | 51500000 | 38400000000 | 34300000000000 | 0.4942 | 0.1738 | 0.0577 | 0.0022 | 0.1982 | 0.0147 | 0.2589 | 0.0932 | 0.1590 | 0.1398 | 0.1250 | 0.1746 | 0.0895 | 0.1735 | 0.0643 | 0.1315 | 0.0348 | 0.1305 | 0.0126 | 0.1401 | 0.0006 | 0.0002 | 0.0021 | 0.0007 | 0.0027 | 0.0018 | 0.0144 | 0.0103 | 0.0681 | 0.0533 | 0.1264 | 0.0962 | 0.0930 | 0.0790 | 0.1328 | 0.1098 | 0.5599 | 0.6487 | 0.0006 | 0.0017 | 0.0011 | 0.0058 | 0.0108 | 0.0178 | 0.0354 | 0.0463 | 0.1058 | 0.1014 | 0.1580 | 0.1570 | 0.1044 | 0.1056 | 0.1298 | 0.1395 | 0.4541 | 0.4249 | 0.0000 | 0.0012 | 0.0063 | 0.0167 | 0.0951 | 0.1417 | 0.1103 | 0.1347 | 0.4942 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 956 | 481 | | 1986 | 9878 | 45.3 | 11.48 | 35.21 | 55.46 | 30 | 34 | 39 | 42 | 45 | 48 | 51 | 56 | 60 | 0.0765 | 756 | 0.806 | 36.77 | 10.44 | 2 | 0.0539 | 107 | 0.0083 | 3.62 | 5.056 | 0.4649 | 2186.4 | 111365 | 5950000 | 331000000 | 0.4003 | 0.2238 | 0.0019 | 0.0000 | 0.0028 | 0.0011 | 0.0131 | 0.0045 | 0.0327 | 0.0129 | 0.0515 | 0.0286 | 0.0776 | 0.0432 | 0.1132 | 0.0510 | 0.1506 | 0.0875 | 0.5566 | 0.7712 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0039 | 0.0021 | 0.0129 | 0.0078 | 0.0207 | 0.0204 | 0.0311 | 0.0266 | 0.0317 | 0.0282 | 0.0498 | 0.0408 | 0.8485 | 0.8741 | 0.0084 | 0.0229 | 0.0231 | 0.0458 | 0.0231 | 0.1069 | 0.0273 | 0.0992 | 0.0588 | 0.0840 | 0.0546 | 0.0992 | 0.0777 | 0.1603 | 0.1387 | 0.1221 | 0.5882 | 0.2595 | 0.0019 | 0.0058 | 0.0145 | 0.0270 | 0.0462 | 0.0568 | 0.0751 | 0.0934 | 0.6792 | 12 | 14 | 15 | 16 | 18 | 22 | 28 | 39 | 66 | 0.3765 | 2.00 | 2.023 | 0.8544 | 4314.9 | 1380000 | 642000000 | 351000000000 | 0.5769 | 0.1123 | 0.0338 | 0.0176 | 0.0938 | 0.0290 | 0.1429 | 0.0522 | 0.1420 | 0.0746 | 0.1488 | 0.1228 | 0.1505 | 0.1485 | 0.1234 | 0.1246 | 0.1023 | 0.1456 | 0.0626 | 0.2849 | 0.0033 | 0.0112 | 0.0063 | 0.0160 | 0.0139 | 0.0227 | 0.0325 | 0.0284 | 0.0634 | 0.0516 | 0.0933 | 0.0672 | 0.0863 | 0.0700 | 0.1218 | 0.1011 | 0.5792 | 0.6317 | 0.0016 | 0.0048 | 0.0055 | 0.0068 | 0.0131 | 0.0109 | 0.0344 | 0.0505 | 0.1071 | 0.1038 | 0.1301 | 0.1633 | 0.0945 | 0.1004 | 0.1519 | 0.1346 | 0.4617 | 0.4249 | 0.0047 | 0.0060 | 0.0125 | 0.0324 | 0.0824 | 0.1100 | 0.0846 | 0.1342 | 0.5332 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1301 | 922 | | 1366 | 2845 | 88.3 | 15.42 | 119.74 | 63.45 | 71 | 75 | 79 | 82 | 86 | 89 | 94 | 101 | 110 | 0.1547 | 440 | 0.932 | 89.36 | 30.02 | 1 | 0.1808 | 247 | 0.0068 | 9.05 | 5.271 | 0.3306 | 8028.3 | 753530 | 73100000 | 7320000000 | 0.4490 | 0.1982 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0164 | 0.0023 | 0.0733 | 0.0233 | 0.1485 | 0.0593 | 0.1736 | 0.0360 | 0.2343 | 0.0765 | 0.3481 | 0.8027 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0081 | 0.0022 | 0.0422 | 0.0205 | 0.0755 | 0.0490 | 0.0739 | 0.0190 | 0.1226 | 0.0381 | 0.6761 | 0.8712 | 0.0256 | 0.0303 | 0.0615 | 0.1515 | 0.0308 | 0.1515 | 0.1538 | 0.1212 | 0.1538 | 0.1515 | 0.1590 | 0.2121 | 0.1385 | 0.0909 | 0.1590 | 0.0606 | 0.1179 | 0.0303 | 0.0065 | 0.0114 | 0.0244 | 0.0603 | 0.0945 | 0.1222 | 0.1596 | 0.1417 | 0.3795 | 46 | 63 | 81 | 98 | 113 | 127 | 144 | 167 | 202 | 0.0075 | 7.31 | 5.265 | 0.4258 | 18362.3 | 3410000 | 742000000 | 186000000000 | 0.5900 | 0.1093 | 0.0045 | 0.0032 | 0.0465 | 0.0127 | 0.1213 | 0.0222 | 0.1122 | 0.0565 | 0.1655 | 0.1016 | 0.1565 | 0.1479 | 0.1565 | 0.1384 | 0.1168 | 0.1625 | 0.1202 | 0.3549 | 0.0000 | 0.0019 | 0.0063 | 0.0042 | 0.0091 | 0.0070 | 0.0223 | 0.0164 | 0.0566 | 0.0529 | 0.1189 | 0.0791 | 0.0840 | 0.0669 | 0.1309 | 0.0993 | 0.5720 | 0.6723 | 0.0046 | 0.0107 | 0.0092 | 0.0143 | 0.0288 | 0.0481 | 0.0714 | 0.1016 | 0.1429 | 0.1373 | 0.1705 | 0.1836 | 0.1244 | 0.1390 | 0.1244 | 0.1622 | 0.3237 | 0.2032 | 0.0000 | 0.0101 | 0.0155 | 0.0364 | 0.1006 | 0.1509 | 0.1223 | 0.1409 | 0.4234 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 470 | 334 | | 17082 | 34713 | 121.5 | 40.86 | 150.26 | 149.90 | 78 | 87 | 96 | 104 | 113 | 124 | 137 | 153 | 176 | 0.0613 | 2127 | 0.917 | 53.45 | 21.26 | 5 | 0.0091 | 155 | 0.0008 | 47.08 | 7.438 | 0.1848 | 16426.1 | 2470000 | 412000000 | 75400000000 | 0.5115 | 0.1584 | 0.0012 | 0.0001 | 0.0040 | 0.0001 | 0.0120 | 0.0016 | 0.0473 | 0.0092 | 0.1219 | 0.0386 | 0.1808 | 0.0802 | 0.1691 | 0.0807 | 0.1727 | 0.1152 | 0.2911 | 0.6742 | 0.0005 | 0.0001 | 0.0019 | 0.0001 | 0.0033 | 0.0009 | 0.0140 | 0.0056 | 0.0416 | 0.0205 | 0.0689 | 0.0420 | 0.0618 | 0.0336 | 0.0900 | 0.0533 | 0.7179 | 0.8439 | 0.0012 | 0.0043 | 0.0043 | 0.0104 | 0.0127 | 0.0293 | 0.0437 | 0.0804 | 0.1009 | 0.1268 | 0.1386 | 0.1608 | 0.1105 | 0.1154 | 0.1410 | 0.1334 | 0.4469 | 0.3392 | 0.0011 | 0.0023 | 0.0098 | 0.0256 | 0.0655 | 0.1021 | 0.0917 | 0.1081 | 0.5939 | 13 | 20 | 40 | 73 | 109 | 146 | 192 | 255 | 354 | 0.0246 | 17.30 | 5.572 | 0.4804 | 45049.4 | 19600000 | 11700000000 | 9560000000000 | 0.5599 | 0.1198 | 0.0163 | 0.0018 | 0.0736 | 0.0061 | 0.1603 | 0.0328 | 0.1540 | 0.0660 | 0.1820 | 0.1370 | 0.1647 | 0.1862 | 0.1066 | 0.1461 | 0.0830 | 0.1520 | 0.0595 | 0.2718 | 0.0002 | 0.0004 | 0.0015 | 0.0006 | 0.0032 | 0.0019 | 0.0118 | 0.0080 | 0.0480 | 0.0350 | 0.0826 | 0.0652 | 0.0678 | 0.0531 | 0.0929 | 0.0754 | 0.6920 | 0.7604 | 0.0006 | 0.0013 | 0.0019 | 0.0026 | 0.0068 | 0.0081 | 0.0218 | 0.0295 | 0.0745 | 0.0894 | 0.1255 | 0.1446 | 0.0963 | 0.1068 | 0.1258 | 0.1351 | 0.5468 | 0.4826 | 0.0005 | 0.0014 | 0.0039 | 0.0169 | 0.0590 | 0.1040 | 0.0801 | 0.1148 | 0.6194 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 396 | 817 | | 4083 | 6204 | 171.9 | 49.75 | 200.16 | 197.44 | 116 | 132 | 144 | 155 | 165 | 176 | 190 | 208 | 235 | 0.1065 | 661 | 1.221 | 103.16 | 41.87 | 1 | 0.0649 | 265 | 0.0012 | 45.98 | 6.996 | 0.1927 | 32023.5 | 6460000 | 1410000000 | 334000000000 | 0.4304 | 0.2154 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0147 | 0.0000 | 0.0334 | 0.0020 | 0.1068 | 0.0322 | 0.2065 | 0.0772 | 0.1709 | 0.0735 | 0.1794 | 0.0958 | 0.2875 | 0.7193 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0068 | 0.0013 | 0.0444 | 0.0205 | 0.0995 | 0.0407 | 0.0762 | 0.0329 | 0.1105 | 0.0477 | 0.6614 | 0.8570 | 0.0036 | 0.0000 | 0.0072 | 0.0256 | 0.0191 | 0.0484 | 0.0656 | 0.0769 | 0.1514 | 0.1852 | 0.1907 | 0.2080 | 0.1085 | 0.1026 | 0.1347 | 0.1453 | 0.3194 | 0.2080 | 0.0006 | 0.0055 | 0.0094 | 0.0303 | 0.1069 | 0.1416 | 0.1085 | 0.1344 | 0.4628 | 19 | 36 | 62 | 91 | 131 | 181 | 248 | 345 | 503 | 0.0039 | 114.79 | 6.970 | 0.2743 | 79040.1 | 42000000 | 26100000000 | 18000000000000 | 0.5116 | 0.1429 | 0.0379 | 0.0018 | 0.1569 | 0.0147 | 0.2288 | 0.0728 | 0.2157 | 0.1053 | 0.1542 | 0.1818 | 0.1085 | 0.2240 | 0.0549 | 0.1567 | 0.0275 | 0.1206 | 0.0157 | 0.1224 | 0.0011 | 0.0003 | 0.0022 | 0.0025 | 0.0037 | 0.0040 | 0.0145 | 0.0126 | 0.0764 | 0.0596 | 0.1135 | 0.1007 | 0.0827 | 0.0795 | 0.1228 | 0.1057 | 0.5829 | 0.6351 | 0.0010 | 0.0006 | 0.0031 | 0.0006 | 0.0078 | 0.0049 | 0.0259 | 0.0401 | 0.0953 | 0.1048 | 0.1472 | 0.1572 | 0.0969 | 0.1030 | 0.1358 | 0.1393 | 0.4870 | 0.4494 | 0.0004 | 0.0035 | 0.0031 | 0.0189 | 0.0817 | 0.1339 | 0.0935 | 0.1299 | 0.5351 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 68 | 826 | | 4128 | 6864 | 146.8 | 44.75 | 144.31 | 126.93 | 100 | 110 | 118 | 127 | 136 | 147 | 160 | 181 | 211 | 0.1005 | 690 | 1.168 | 86.40 | 31.91 | 1 | 0.0540 | 223 | 0.0017 | 33.02 | 6.715 | 0.2229 | 23554.4 | 4140000 | 797000000 | 166000000000 | 0.3837 | 0.2702 | 0.0030 | 0.0000 | 0.0044 | 0.0000 | 0.0178 | 0.0020 | 0.0435 | 0.0054 | 0.1156 | 0.0363 | 0.1789 | 0.0632 | 0.1848 | 0.0697 | 0.1912 | 0.1133 | 0.2609 | 0.7102 | 0.0021 | 0.0000 | 0.0021 | 0.0000 | 0.0065 | 0.0008 | 0.0174 | 0.0018 | 0.0533 | 0.0206 | 0.0793 | 0.0323 | 0.0854 | 0.0354 | 0.1083 | 0.0652 | 0.6456 | 0.8440 | 0.0011 | 0.0066 | 0.0033 | 0.0087 | 0.0299 | 0.0175 | 0.0421 | 0.0611 | 0.0965 | 0.1332 | 0.1275 | 0.1681 | 0.0976 | 0.1201 | 0.1197 | 0.1638 | 0.4823 | 0.3210 | 0.0024 | 0.0042 | 0.0180 | 0.0342 | 0.0792 | 0.1104 | 0.0870 | 0.1309 | 0.5336 | 30 | 44 | 59 | 79 | 101 | 131 | 171 | 232 | 322 | 0.0037 | 48.50 | 6.480 | 0.3040 | 36934.0 | 13300000 | 5910000000 | 3030000000000 | 0.5053 | 0.1536 | 0.0289 | 0.0009 | 0.1252 | 0.0109 | 0.1753 | 0.0639 | 0.1667 | 0.0948 | 0.1830 | 0.1501 | 0.1532 | 0.1791 | 0.0886 | 0.1497 | 0.0559 | 0.1542 | 0.0231 | 0.1964 | 0.0016 | 0.0003 | 0.0026 | 0.0026 | 0.0078 | 0.0059 | 0.0260 | 0.0221 | 0.0809 | 0.0635 | 0.1135 | 0.0910 | 0.0891 | 0.0846 | 0.1135 | 0.1116 | 0.5650 | 0.6183 | 0.0020 | 0.0018 | 0.0025 | 0.0077 | 0.0088 | 0.0196 | 0.0471 | 0.0422 | 0.0972 | 0.1040 | 0.1290 | 0.1337 | 0.1035 | 0.1040 | 0.1295 | 0.1349 | 0.4804 | 0.4522 | 0.0000 | 0.0060 | 0.0116 | 0.0344 | 0.0800 | 0.1244 | 0.1000 | 0.1224 | 0.5214 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 834 | 433 | | 10028 | 23515 | 170.4 | 45.07 | 251.81 | 223.41 | 116 | 130 | 142 | 154 | 167 | 180 | 195 | 212 | 231 | 0.0643 | 1511 | 0.433 | 138.81 | 20.40 | 4 | 0.0343 | 344 | 0.0006 | 58.13 | 7.696 | 0.1518 | 31076.2 | 6010000 | 1230000000 | 261000000000 | 0.4626 | 0.2012 | 0.0014 | 0.0001 | 0.0014 | 0.0000 | 0.0051 | 0.0010 | 0.0350 | 0.0070 | 0.1108 | 0.0315 | 0.1699 | 0.0658 | 0.1503 | 0.0658 | 0.1738 | 0.0971 | 0.3522 | 0.7316 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0007 | 0.0127 | 0.0044 | 0.0411 | 0.0206 | 0.0636 | 0.0401 | 0.0541 | 0.0301 | 0.0732 | 0.0469 | 0.7527 | 0.8573 | 0.0016 | 0.0064 | 0.0036 | 0.0242 | 0.0121 | 0.0382 | 0.0395 | 0.1057 | 0.0999 | 0.1643 | 0.1386 | 0.1771 | 0.1185 | 0.1414 | 0.1350 | 0.1210 | 0.4512 | 0.2217 | 0.0013 | 0.0027 | 0.0055 | 0.0224 | 0.0554 | 0.0952 | 0.0829 | 0.1036 | 0.6310 | 27 | 65 | 104 | 142 | 188 | 246 | 318 | 410 | 550 | 0.0043 | 51.61 | 6.756 | 0.3199 | 113315.0 | 70500000 | 54700000000 | 49800000000000 | 0.5106 | 0.1551 | 0.0197 | 0.0009 | 0.0972 | 0.0050 | 0.2185 | 0.0351 | 0.1851 | 0.0833 | 0.1744 | 0.1635 | 0.1413 | 0.2193 | 0.0821 | 0.1599 | 0.0479 | 0.1407 | 0.0337 | 0.1922 | 0.0004 | 0.0003 | 0.0007 | 0.0007 | 0.0030 | 0.0032 | 0.0179 | 0.0117 | 0.0615 | 0.0449 | 0.0961 | 0.0795 | 0.0799 | 0.0637 | 0.0995 | 0.0868 | 0.6409 | 0.7092 | 0.0008 | 0.0013 | 0.0027 | 0.0038 | 0.0078 | 0.0110 | 0.0324 | 0.0428 | 0.0867 | 0.1042 | 0.1373 | 0.1566 | 0.0965 | 0.1074 | 0.1356 | 0.1445 | 0.5003 | 0.4284 | 0.0004 | 0.0017 | 0.0054 | 0.0273 | 0.0740 | 0.1165 | 0.0851 | 0.1169 | 0.5726 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 615 | 87 | | 3644 | 13644 | 486.1 | 117.15 | 117.91 | 188.35 | 319 | 379 | 428 | 463 | 490 | 516 | 545 | 579 | 629 | 0.0704 | 960 | 0.778 | 78.75 | 25.08 | 2 | 0.0645 | 235 | 0.0008 | 59.20 | 7.366 | 0.1629 | 250045.0 | 135000000 | 76400000000 | 45000000000000 | 0.3808 | 0.2634 | 0.0005 | 0.0003 | 0.0023 | 0.0006 | 0.0065 | 0.0012 | 0.0208 | 0.0024 | 0.0644 | 0.0260 | 0.1185 | 0.0474 | 0.1181 | 0.0477 | 0.1537 | 0.0608 | 0.5153 | 0.8136 | 0.0004 | 0.0003 | 0.0004 | 0.0006 | 0.0025 | 0.0009 | 0.0053 | 0.0017 | 0.0246 | 0.0206 | 0.0421 | 0.0342 | 0.0333 | 0.0284 | 0.0512 | 0.0353 | 0.8404 | 0.8781 | 0.0029 | 0.0165 | 0.0072 | 0.0110 | 0.0435 | 0.0165 | 0.0609 | 0.0824 | 0.1493 | 0.1319 | 0.1493 | 0.1648 | 0.1232 | 0.1044 | 0.1130 | 0.1154 | 0.3507 | 0.3571 | 0.0011 | 0.0005 | 0.0037 | 0.0186 | 0.0541 | 0.0981 | 0.1140 | 0.1352 | 0.5748 | 5 | 7 | 9 | 12 | 18 | 41 | 105 | 209 | 414 | 0.0925 | 12.28 | 4.224 | 0.5614 | 49376.8 | 28700000 | 20000000000 | 16200000000000 | 0.4378 | 0.2206 | 0.0432 | 0.0012 | 0.1512 | 0.0148 | 0.2160 | 0.0598 | 0.1677 | 0.1006 | 0.1423 | 0.1764 | 0.1017 | 0.1795 | 0.0839 | 0.1388 | 0.0597 | 0.1184 | 0.0343 | 0.2104 | 0.0002 | 0.0000 | 0.0007 | 0.0011 | 0.0035 | 0.0013 | 0.0091 | 0.0065 | 0.0424 | 0.0378 | 0.0666 | 0.0551 | 0.0544 | 0.0477 | 0.0811 | 0.0656 | 0.7419 | 0.7849 | 0.0006 | 0.0006 | 0.0023 | 0.0029 | 0.0046 | 0.0048 | 0.0126 | 0.0140 | 0.0584 | 0.0619 | 0.0822 | 0.0909 | 0.0664 | 0.0635 | 0.0908 | 0.0804 | 0.6821 | 0.6810 | 0.0000 | 0.0018 | 0.0028 | 0.0106 | 0.0536 | 0.0732 | 0.0590 | 0.0912 | 0.7077 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 958 | 125 | | 2932 | 10604 | 196.6 | 65.96 | 9.01 | 4.41 | 127 | 138 | 150 | 164 | 179 | 198 | 223 | 249 | 301 | 0.0658 | 698 | 0.614 | 76.01 | 21.95 | 1 | 0.0836 | 245 | 0.0079 | 2.74 | 5.180 | 0.5006 | 42980.6 | 10400000 | 2760000000 | 788000000000 | 0.4076 | 0.2304 | 0.0043 | 0.0013 | 0.0035 | 0.0013 | 0.0112 | 0.0042 | 0.0371 | 0.0097 | 0.0569 | 0.0295 | 0.1320 | 0.0687 | 0.1217 | 0.0442 | 0.1639 | 0.0720 | 0.4694 | 0.7692 | 0.0021 | 0.0011 | 0.0021 | 0.0007 | 0.0053 | 0.0032 | 0.0137 | 0.0064 | 0.0217 | 0.0207 | 0.0455 | 0.0454 | 0.0418 | 0.0264 | 0.0561 | 0.0482 | 0.8117 | 0.8477 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0109 | 0.0047 | 0.0301 | 0.0165 | 0.0342 | 0.0425 | 0.0861 | 0.0778 | 0.0697 | 0.0472 | 0.0765 | 0.0802 | 0.6899 | 0.7311 | 0.0017 | 0.0025 | 0.0042 | 0.0151 | 0.0260 | 0.0519 | 0.0511 | 0.0611 | 0.7864 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 14 | 0.0111 | 13.72 | 5.076 | 0.3038 | 100.7 | 1416.1 | 25055.2 | 539238 | 0.4587 | 0.1802 | 0.0400 | 0.0040 | 0.1247 | 0.0070 | 0.2092 | 0.0206 | 0.2582 | 0.0465 | 0.1991 | 0.1010 | 0.1141 | 0.1792 | 0.0447 | 0.2550 | 0.0098 | 0.2595 | 0.0003 | 0.1273 | 0.0087 | 0.0002 | 0.0392 | 0.0012 | 0.0841 | 0.0078 | 0.1282 | 0.0233 | 0.1444 | 0.0654 | 0.1470 | 0.1201 | 0.1169 | 0.1781 | 0.1209 | 0.2377 | 0.2107 | 0.3662 | 0.1147 | 0.1071 | 0.0900 | 0.0750 | 0.0862 | 0.0679 | 0.0718 | 0.0968 | 0.0938 | 0.0859 | 0.1045 | 0.1000 | 0.0836 | 0.1019 | 0.0957 | 0.1167 | 0.2595 | 0.2487 | 0.0483 | 0.0956 | 0.1102 | 0.1089 | 0.1085 | 0.0986 | 0.0902 | 0.1128 | 0.2269 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1179 | 189 | | 16382 | 26563 | 119.9 | 50.77 | 96.33 | 96.08 | 57 | 80 | 93 | 105 | 115 | 128 | 142 | 159 | 186 | 0.0652 | 1732 | 0.279 | 134.45 | 18.44 | 8 | 0.0245 | 401 | 0.0012 | 34.16 | 7.111 | 0.2279 | 16954.2 | 2720000 | 485000000 | 94900000000 | 0.4885 | 0.1704 | 0.0014 | 0.0001 | 0.0069 | 0.0005 | 0.0266 | 0.0024 | 0.0715 | 0.0104 | 0.1597 | 0.0480 | 0.2113 | 0.0993 | 0.1753 | 0.1092 | 0.1597 | 0.1428 | 0.1876 | 0.5873 | 0.0004 | 0.0001 | 0.0017 | 0.0003 | 0.0033 | 0.0012 | 0.0102 | 0.0037 | 0.0386 | 0.0208 | 0.0699 | 0.0357 | 0.0674 | 0.0386 | 0.0962 | 0.0530 | 0.7123 | 0.8467 | 0.0017 | 0.0038 | 0.0051 | 0.0091 | 0.0110 | 0.0152 | 0.0442 | 0.0800 | 0.1188 | 0.1523 | 0.1512 | 0.1789 | 0.1184 | 0.1144 | 0.1491 | 0.1413 | 0.4006 | 0.3050 | 0.0009 | 0.0013 | 0.0058 | 0.0245 | 0.0728 | 0.1185 | 0.1037 | 0.1302 | 0.5422 | 15 | 22 | 32 | 46 | 64 | 86 | 117 | 158 | 222 | 0.0165 | 11.29 | 5.277 | 0.4716 | 18511.3 | 5390000 | 2090000000 | 994000000000 | 0.5640 | 0.1104 | 0.0416 | 0.0021 | 0.1298 | 0.0145 | 0.2417 | 0.0717 | 0.1786 | 0.1322 | 0.1563 | 0.1705 | 0.1056 | 0.1818 | 0.0805 | 0.1400 | 0.0452 | 0.1272 | 0.0207 | 0.1600 | 0.0013 | 0.0006 | 0.0026 | 0.0025 | 0.0052 | 0.0043 | 0.0226 | 0.0158 | 0.0717 | 0.0537 | 0.1141 | 0.0969 | 0.0904 | 0.0786 | 0.1320 | 0.1170 | 0.5601 | 0.6307 | 0.0017 | 0.0015 | 0.0030 | 0.0031 | 0.0089 | 0.0133 | 0.0324 | 0.0402 | 0.0970 | 0.1132 | 0.1484 | 0.1592 | 0.1051 | 0.1113 | 0.1413 | 0.1490 | 0.4622 | 0.4093 | 0.0015 | 0.0038 | 0.0079 | 0.0238 | 0.0829 | 0.1287 | 0.1026 | 0.1362 | 0.5125 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 157 | 329 | | 1738 | 4874 | 829.9 | 218.86 | 12.72 | 6.17 | 545 | 606 | 672 | 746 | 818 | 889 | 972 | 1058 | 1144 | 0.0903 | 440 | 1.050 | 47.54 | 16.03 | 1 | 0.0702 | 122 | 0.0011 | 32.34 | 6.913 | 0.1942 | 736559.0 | 692000000 | 681000000000 | 695000000000000 | 0.3830 | 0.2470 | 0.0000 | 0.0006 | 0.0000 | 0.0006 | 0.0039 | 0.0013 | 0.0209 | 0.0071 | 0.0706 | 0.0292 | 0.1033 | 0.0565 | 0.0928 | 0.0435 | 0.1294 | 0.0617 | 0.5791 | 0.7994 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0057 | 0.0024 | 0.0283 | 0.0209 | 0.0404 | 0.0435 | 0.0323 | 0.0215 | 0.0477 | 0.0316 | 0.8448 | 0.8802 | 0.0021 | 0.0217 | 0.0042 | 0.0145 | 0.0064 | 0.0145 | 0.0169 | 0.0725 | 0.0360 | 0.0870 | 0.0636 | 0.0797 | 0.0487 | 0.1377 | 0.0805 | 0.2101 | 0.7415 | 0.3623 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0311 | 0.0587 | 0.0335 | 0.0467 | 0.8228 | 7 | 8 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 0.0061 | 22.32 | 5.502 | 0.2607 | 199.8 | 4679.1 | 209109 | 15400000 | 0.5319 | 0.1291 | 0.0389 | 0.0014 | 0.1029 | 0.0079 | 0.1520 | 0.0200 | 0.1856 | 0.0485 | 0.2128 | 0.0891 | 0.1653 | 0.1213 | 0.0976 | 0.2022 | 0.0368 | 0.2799 | 0.0080 | 0.2298 | 0.0185 | 0.0007 | 0.0406 | 0.0045 | 0.0564 | 0.0121 | 0.0554 | 0.0289 | 0.0716 | 0.0535 | 0.0848 | 0.0705 | 0.1039 | 0.1025 | 0.1729 | 0.1735 | 0.3959 | 0.5540 | 0.0744 | 0.1222 | 0.0666 | 0.1109 | 0.1055 | 0.1598 | 0.1038 | 0.1297 | 0.1176 | 0.1297 | 0.1272 | 0.1034 | 0.1375 | 0.1034 | 0.1280 | 0.0658 | 0.1393 | 0.0752 | 0.0362 | 0.0460 | 0.0596 | 0.0732 | 0.0779 | 0.1009 | 0.1300 | 0.2155 | 0.2606 |