High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 755 | 233 | 6882 | 11035 | 750.8 | 130.11 | 50.30 | 107.22 | 589 | 637 | 676 | 712 | 743 | 780 | 818 | 862 | 917 | 0.0847 | 935 | 0.936 | 120.35 | 37.05 | 2 | 0.0442 | 304 | 0.0010 | 30.30 | 7.224 | 0.2258 | 580634.0 | 462000000 | 378000000000 | 319000000000000 | 0.4407 | 0.2046 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0019 | 0.0001 | 0.0078 | 0.0003 | 0.0358 | 0.0142 | 0.0524 | 0.0228 | 0.0553 | 0.0152 | 0.0717 | 0.0231 | 0.7735 | 0.9243 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0031 | 0.0003 | 0.0186 | 0.0130 | 0.0277 | 0.0192 | 0.0279 | 0.0119 | 0.0379 | 0.0175 | 0.8843 | 0.9381 | 0.0012 | 0.0000 | 0.0048 | 0.0000 | 0.0203 | 0.0102 | 0.0501 | 0.1122 | 0.0776 | 0.0918 | 0.1241 | 0.1531 | 0.1181 | 0.1122 | 0.1050 | 0.1429 | 0.4988 | 0.3776 | 0.0009 | 0.0021 | 0.0039 | 0.0173 | 0.0318 | 0.0500 | 0.0518 | 0.0760 | 0.7662 | 7 | 9 | 11 | 12 | 15 | 19 | 26 | 42 | 126 | 0.0842 | 13.28 | 3.740 | 0.6597 | 14024.1 | 7570000 | 5380000000 | 4510000000000 | 0.4239 | 0.2208 | 0.0278 | 0.0089 | 0.0872 | 0.0149 | 0.1930 | 0.0343 | 0.1818 | 0.0961 | 0.1781 | 0.1586 | 0.1447 | 0.1571 | 0.1095 | 0.1400 | 0.0538 | 0.1482 | 0.0241 | 0.2420 | 0.0017 | 0.0034 | 0.0022 | 0.0044 | 0.0074 | 0.0065 | 0.0288 | 0.0266 | 0.0616 | 0.0536 | 0.0634 | 0.0615 | 0.0621 | 0.0663 | 0.0743 | 0.0844 | 0.6984 | 0.6933 | 0.0000 | 0.0013 | 0.0011 | 0.0013 | 0.0046 | 0.0019 | 0.0194 | 0.0183 | 0.0549 | 0.0593 | 0.0800 | 0.0732 | 0.0446 | 0.0511 | 0.0652 | 0.0650 | 0.7301 | 0.7287 | 0.0015 | 0.0025 | 0.0041 | 0.0259 | 0.0498 | 0.0747 | 0.0503 | 0.0711 | 0.7202 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 318 | 398 | 21149 | 32393 | 118.4 | 36.13 | 198.09 | 230.96 | 79 | 89 | 97 | 105 | 112 | 121 | 131 | 144 | 166 | 0.0593 | 1920 | 0.736 | 173.25 | 37.64 | 3 | 0.0214 | 452 | 0.0021 | 20.81 | 6.559 | 0.2661 | 15334.3 | 2180000 | 343000000 | 59700000000 | 0.4453 | 0.2046 | 0.0012 | 0.0001 | 0.0027 | 0.0003 | 0.0109 | 0.0011 | 0.0349 | 0.0049 | 0.1040 | 0.0257 | 0.1712 | 0.0574 | 0.1644 | 0.0633 | 0.1813 | 0.0975 | 0.3295 | 0.7498 | 0.0006 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0008 | 0.0116 | 0.0021 | 0.0381 | 0.0130 | 0.0636 | 0.0258 | 0.0677 | 0.0265 | 0.0964 | 0.0418 | 0.7166 | 0.8899 | 0.0030 | 0.0065 | 0.0063 | 0.0145 | 0.0203 | 0.0187 | 0.0586 | 0.0816 | 0.1155 | 0.1493 | 0.1471 | 0.1968 | 0.1274 | 0.1129 | 0.1298 | 0.1399 | 0.3918 | 0.2799 | 0.0020 | 0.0048 | 0.0084 | 0.0315 | 0.0770 | 0.1122 | 0.0985 | 0.1278 | 0.5378 | 14 | 17 | 25 | 48 | 96 | 167 | 259 | 373 | 535 | 0.0276 | 93.42 | 6.409 | 0.3746 | 92580.9 | 58500000 | 44100000000 | 37800000000000 | 0.5719 | 0.1057 | 0.0647 | 0.0020 | 0.2147 | 0.0220 | 0.2542 | 0.1155 | 0.1479 | 0.1648 | 0.1256 | 0.1968 | 0.0936 | 0.1670 | 0.0523 | 0.1282 | 0.0303 | 0.0948 | 0.0169 | 0.1089 | 0.0004 | 0.0002 | 0.0013 | 0.0011 | 0.0026 | 0.0022 | 0.0119 | 0.0095 | 0.0574 | 0.0487 | 0.0985 | 0.0827 | 0.0773 | 0.0653 | 0.1116 | 0.0939 | 0.6390 | 0.6965 | 0.0004 | 0.0003 | 0.0016 | 0.0021 | 0.0053 | 0.0067 | 0.0183 | 0.0246 | 0.0756 | 0.0872 | 0.1236 | 0.1318 | 0.0932 | 0.1017 | 0.1281 | 0.1345 | 0.5539 | 0.5111 | 0.0007 | 0.0017 | 0.0031 | 0.0149 | 0.0664 | 0.1128 | 0.0859 | 0.1198 | 0.5947 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 816 | 393 | 5950 | 11342 | 117.6 | 33.32 | 249.29 | 173.91 | 81 | 90 | 98 | 105 | 112 | 120 | 129 | 141 | 162 | 0.0886 | 1005 | 0.628 | 179.79 | 48.30 | 1 | 0.0987 | 587 | 0.0027 | 14.82 | 6.257 | 0.2986 | 14935.3 | 2060000 | 307000000 | 49700000000 | 0.4437 | 0.2043 | 0.0009 | 0.0002 | 0.0033 | 0.0000 | 0.0082 | 0.0002 | 0.0331 | 0.0046 | 0.0759 | 0.0228 | 0.1588 | 0.0532 | 0.1527 | 0.0566 | 0.1907 | 0.0777 | 0.3764 | 0.7848 | 0.0005 | 0.0002 | 0.0014 | 0.0000 | 0.0036 | 0.0002 | 0.0167 | 0.0016 | 0.0351 | 0.0130 | 0.0689 | 0.0288 | 0.0680 | 0.0227 | 0.0975 | 0.0363 | 0.7084 | 0.8972 | 0.0052 | 0.0056 | 0.0070 | 0.0056 | 0.0235 | 0.0206 | 0.0506 | 0.0882 | 0.0950 | 0.1689 | 0.1578 | 0.1388 | 0.1046 | 0.1107 | 0.1290 | 0.1370 | 0.4272 | 0.3246 | 0.0020 | 0.0051 | 0.0094 | 0.0279 | 0.0822 | 0.1188 | 0.0917 | 0.1200 | 0.5429 | 40 | 81 | 128 | 176 | 225 | 279 | 333 | 394 | 483 | 0.0016 | 78.48 | 7.365 | 0.2033 | 92387.6 | 42200000 | 22200000000 | 13200000000000 | 0.4848 | 0.1839 | 0.0286 | 0.0012 | 0.1297 | 0.0127 | 0.2654 | 0.0476 | 0.1826 | 0.1174 | 0.1568 | 0.1874 | 0.1170 | 0.2093 | 0.0749 | 0.1488 | 0.0314 | 0.1305 | 0.0136 | 0.1451 | 0.0005 | 0.0000 | 0.0003 | 0.0013 | 0.0040 | 0.0026 | 0.0198 | 0.0140 | 0.0727 | 0.0554 | 0.1270 | 0.1033 | 0.1058 | 0.0836 | 0.1312 | 0.1196 | 0.5388 | 0.6202 | 0.0012 | 0.0026 | 0.0065 | 0.0077 | 0.0102 | 0.0148 | 0.0349 | 0.0586 | 0.1118 | 0.1501 | 0.1780 | 0.1978 | 0.1268 | 0.1369 | 0.1581 | 0.1553 | 0.3725 | 0.2761 | 0.0002 | 0.0031 | 0.0062 | 0.0306 | 0.0849 | 0.1491 | 0.1161 | 0.1500 | 0.4598 | |
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 949 | 628 | 5444 | 5921 | 503.2 | 113.35 | 118.69 | 220.33 | 340 | 443 | 485 | 510 | 528 | 546 | 564 | 585 | 614 | 0.1099 | 651 | 1.294 | 20.22 | 8.60 | 1 | 0.0103 | 56 | 0.0029 | 17.80 | 6.312 | 0.3065 | 266047.0 | 145000000 | 80700000000 | 45600000000000 | 0.4084 | 0.2255 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0074 | 0.0008 | 0.0372 | 0.0133 | 0.0597 | 0.0230 | 0.0638 | 0.0153 | 0.1089 | 0.0266 | 0.7193 | 0.9208 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0158 | 0.0130 | 0.0270 | 0.0200 | 0.0203 | 0.0120 | 0.0363 | 0.0200 | 0.8999 | 0.9346 | 0.0097 | 0.0000 | 0.0110 | 0.0789 | 0.0331 | 0.1579 | 0.0607 | 0.0789 | 0.1062 | 0.1842 | 0.1407 | 0.1053 | 0.1407 | 0.0789 | 0.1434 | 0.2105 | 0.3545 | 0.1053 | 0.0000 | 0.0009 | 0.0035 | 0.0087 | 0.0363 | 0.0603 | 0.0609 | 0.0873 | 0.7421 | 7 | 10 | 14 | 19 | 25 | 37 | 74 | 153 | 375 | 0.0775 | 22.34 | 4.056 | 0.5583 | 62626.7 | 51300000 | 50500000000 | 55700000000000 | 0.5274 | 0.1314 | 0.0603 | 0.0015 | 0.2190 | 0.0164 | 0.3175 | 0.0848 | 0.1429 | 0.1711 | 0.1524 | 0.2321 | 0.0603 | 0.2292 | 0.0222 | 0.1295 | 0.0159 | 0.0744 | 0.0095 | 0.0610 | 0.0013 | 0.0006 | 0.0051 | 0.0011 | 0.0019 | 0.0033 | 0.0103 | 0.0094 | 0.0994 | 0.0833 | 0.1186 | 0.1127 | 0.0962 | 0.0944 | 0.1237 | 0.1133 | 0.5436 | 0.5819 | 0.0000 | 0.0009 | 0.0016 | 0.0009 | 0.0072 | 0.0071 | 0.0177 | 0.0301 | 0.1157 | 0.1125 | 0.1301 | 0.1364 | 0.1028 | 0.0912 | 0.1205 | 0.1355 | 0.5044 | 0.4854 | 0.0007 | 0.0007 | 0.0036 | 0.0144 | 0.1114 | 0.1222 | 0.0978 | 0.1258 | 0.5234 | |||
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 | |
Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 153 | 736 | 17577 | 32431 | 213.5 | 66.22 | 119.98 | 191.83 | 136 | 158 | 175 | 190 | 206 | 224 | 243 | 267 | 300 | 0.0595 | 1929 | 0.787 | 314.94 | 107.02 | 13 | 0.0531 | 934 | 0.0006 | 60.12 | 7.718 | 0.1576 | 49951.2 | 12700000 | 3480000000 | 1030000000000 | 0.4279 | 0.2038 | 0.0008 | 0.0001 | 0.0017 | 0.0000 | 0.0105 | 0.0012 | 0.0391 | 0.0061 | 0.0988 | 0.0278 | 0.1631 | 0.0552 | 0.1671 | 0.0671 | 0.1808 | 0.0927 | 0.3382 | 0.7498 | 0.0004 | 0.0001 | 0.0009 | 0.0000 | 0.0031 | 0.0002 | 0.0119 | 0.0026 | 0.0325 | 0.0130 | 0.0602 | 0.0251 | 0.0610 | 0.0279 | 0.0802 | 0.0411 | 0.7497 | 0.8899 | 0.0021 | 0.0077 | 0.0056 | 0.0131 | 0.0162 | 0.0219 | 0.0440 | 0.0848 | 0.0899 | 0.1297 | 0.1362 | 0.1822 | 0.1144 | 0.1160 | 0.1320 | 0.1510 | 0.4596 | 0.2938 | 0.0007 | 0.0020 | 0.0072 | 0.0280 | 0.0589 | 0.0957 | 0.0855 | 0.1131 | 0.6090 | 12 | 15 | 17 | 19 | 25 | 43 | 91 | 197 | 387 | 0.1336 | 21.39 | 4.248 | 0.6174 | 51191.5 | 32500000 | 25000000000 | 21700000000000 | 0.5704 | 0.1134 | 0.0562 | 0.0029 | 0.1967 | 0.0294 | 0.2199 | 0.1289 | 0.1503 | 0.1471 | 0.1472 | 0.1759 | 0.1038 | 0.1638 | 0.0562 | 0.1096 | 0.0452 | 0.1055 | 0.0244 | 0.1370 | 0.0001 | 0.0003 | 0.0006 | 0.0007 | 0.0023 | 0.0022 | 0.0121 | 0.0103 | 0.0469 | 0.0439 | 0.0761 | 0.0620 | 0.0514 | 0.0494 | 0.0790 | 0.0736 | 0.7315 | 0.7577 | 0.0001 | 0.0003 | 0.0009 | 0.0010 | 0.0024 | 0.0040 | 0.0148 | 0.0174 | 0.0598 | 0.0709 | 0.0992 | 0.1012 | 0.0685 | 0.0794 | 0.1031 | 0.1055 | 0.6513 | 0.6204 | 0.0001 | 0.0002 | 0.0016 | 0.0130 | 0.0555 | 0.0840 | 0.0645 | 0.0934 | 0.6877 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1098 | 160 | 13724 | 21102 | 109.6 | 32.03 | 139.67 | 113.32 | 75 | 84 | 91 | 97 | 104 | 112 | 121 | 133 | 152 | 0.0598 | 1262 | 0.543 | 155.77 | 38.28 | 1 | 0.0358 | 491 | 0.0012 | 36.99 | 7.099 | 0.2067 | 13040.5 | 1690000 | 237000000 | 36400000000 | 0.4757 | 0.1867 | 0.0010 | 0.0001 | 0.0041 | 0.0003 | 0.0130 | 0.0016 | 0.0426 | 0.0043 | 0.0995 | 0.0236 | 0.1665 | 0.0560 | 0.1630 | 0.0574 | 0.1878 | 0.0954 | 0.3226 | 0.7614 | 0.0005 | 0.0001 | 0.0013 | 0.0001 | 0.0034 | 0.0002 | 0.0125 | 0.0008 | 0.0402 | 0.0130 | 0.0734 | 0.0252 | 0.0716 | 0.0218 | 0.1009 | 0.0456 | 0.6963 | 0.8934 | 0.0044 | 0.0054 | 0.0078 | 0.0168 | 0.0271 | 0.0337 | 0.0640 | 0.0804 | 0.1118 | 0.1692 | 0.1406 | 0.1937 | 0.1349 | 0.1026 | 0.1386 | 0.1394 | 0.3707 | 0.2588 | 0.0024 | 0.0058 | 0.0129 | 0.0351 | 0.0814 | 0.1154 | 0.0950 | 0.1140 | 0.5380 | 25 | 40 | 60 | 83 | 110 | 142 | 177 | 222 | 298 | 0.0094 | 10.78 | 5.597 | 0.4544 | 32349.4 | 10000000 | 3730000000 | 1590000000000 | 0.5105 | 0.1695 | 0.0131 | 0.0019 | 0.0728 | 0.0040 | 0.1644 | 0.0224 | 0.1683 | 0.0713 | 0.1736 | 0.1476 | 0.1439 | 0.1890 | 0.1111 | 0.1477 | 0.0831 | 0.1506 | 0.0697 | 0.2653 | 0.0009 | 0.0007 | 0.0013 | 0.0014 | 0.0035 | 0.0034 | 0.0133 | 0.0126 | 0.0502 | 0.0386 | 0.0839 | 0.0657 | 0.0680 | 0.0578 | 0.1044 | 0.0854 | 0.6745 | 0.7344 | 0.0012 | 0.0013 | 0.0045 | 0.0041 | 0.0086 | 0.0141 | 0.0281 | 0.0380 | 0.0821 | 0.1031 | 0.1290 | 0.1509 | 0.1030 | 0.1107 | 0.1319 | 0.1375 | 0.5116 | 0.4403 | 0.0013 | 0.0019 | 0.0052 | 0.0196 | 0.0680 | 0.1022 | 0.0904 | 0.1250 | 0.5864 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 861 | 186 | 12331 | 15671 | 289.1 | 82.48 | 116.02 | 160.19 | 201 | 225 | 243 | 260 | 276 | 292 | 314 | 345 | 400 | 0.0849 | 1331 | 0.663 | 177.34 | 56.46 | 4 | 0.0431 | 532 | 0.0008 | 58.20 | 7.495 | 0.1717 | 90380.5 | 30600000 | 11200000000 | 4470000000000 | 0.4343 | 0.2144 | 0.0007 | 0.0000 | 0.0013 | 0.0002 | 0.0081 | 0.0007 | 0.0252 | 0.0037 | 0.0800 | 0.0238 | 0.1386 | 0.0531 | 0.1412 | 0.0533 | 0.1670 | 0.0739 | 0.4380 | 0.7912 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0079 | 0.0009 | 0.0344 | 0.0131 | 0.0694 | 0.0240 | 0.0655 | 0.0205 | 0.0934 | 0.0333 | 0.7273 | 0.9081 | 0.0029 | 0.0034 | 0.0074 | 0.0068 | 0.0153 | 0.0316 | 0.0422 | 0.0769 | 0.1071 | 0.1435 | 0.1468 | 0.1973 | 0.1038 | 0.0991 | 0.1443 | 0.1307 | 0.4301 | 0.3108 | 0.0013 | 0.0040 | 0.0106 | 0.0361 | 0.0748 | 0.1272 | 0.0958 | 0.1105 | 0.5396 | 7 | 10 | 13 | 22 | 43 | 73 | 127 | 212 | 335 | 0.0704 | 13.83 | 4.641 | 0.5316 | 39120.6 | 20200000 | 14100000000 | 12400000000000 | 0.5640 | 0.1235 | 0.0406 | 0.0033 | 0.1589 | 0.0200 | 0.2525 | 0.0850 | 0.1954 | 0.1426 | 0.1432 | 0.1904 | 0.1043 | 0.1814 | 0.0579 | 0.1368 | 0.0281 | 0.1111 | 0.0190 | 0.1295 | 0.0000 | 0.0006 | 0.0009 | 0.0012 | 0.0034 | 0.0027 | 0.0101 | 0.0123 | 0.0575 | 0.0454 | 0.0885 | 0.0709 | 0.0600 | 0.0580 | 0.0942 | 0.0801 | 0.6855 | 0.7288 | 0.0002 | 0.0005 | 0.0009 | 0.0015 | 0.0041 | 0.0040 | 0.0175 | 0.0184 | 0.0723 | 0.0875 | 0.1159 | 0.1187 | 0.0771 | 0.0804 | 0.1104 | 0.1200 | 0.6016 | 0.5689 | 0.0000 | 0.0012 | 0.0028 | 0.0153 | 0.0630 | 0.1041 | 0.0675 | 0.1093 | 0.6367 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 855 | 618 | 6392 | 8692 | 565.9 | 136.42 | 151.51 | 154.48 | 405 | 449 | 487 | 519 | 551 | 583 | 618 | 669 | 747 | 0.0962 | 836 | 1.181 | 149.16 | 56.30 | 1 | 0.0601 | 384 | 0.0005 | 84.49 | 7.736 | 0.1296 | 338887.0 | 215000000 | 144000000000 | 102000000000000 | 0.4381 | 0.2035 | 0.0003 | 0.0000 | 0.0013 | 0.0002 | 0.0021 | 0.0003 | 0.0167 | 0.0026 | 0.0632 | 0.0204 | 0.1182 | 0.0408 | 0.1292 | 0.0333 | 0.1665 | 0.0493 | 0.5027 | 0.8530 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0002 | 0.0063 | 0.0016 | 0.0281 | 0.0131 | 0.0505 | 0.0215 | 0.0583 | 0.0156 | 0.0783 | 0.0233 | 0.7769 | 0.9246 | 0.0026 | 0.0102 | 0.0061 | 0.0051 | 0.0104 | 0.0255 | 0.0494 | 0.0561 | 0.1223 | 0.1378 | 0.1405 | 0.2168 | 0.1119 | 0.1173 | 0.1474 | 0.1505 | 0.4094 | 0.2806 | 0.0014 | 0.0034 | 0.0085 | 0.0263 | 0.0650 | 0.1026 | 0.0988 | 0.1173 | 0.5766 | 16 | 30 | 48 | 69 | 98 | 135 | 183 | 254 | 363 | 0.0144 | 28.33 | 5.755 | 0.4071 | 46815.8 | 20900000 | 11800000000 | 7940000000000 | 0.4493 | 0.1881 | 0.0467 | 0.0022 | 0.1642 | 0.0178 | 0.2921 | 0.0975 | 0.1659 | 0.1300 | 0.1366 | 0.1820 | 0.0977 | 0.1971 | 0.0467 | 0.1443 | 0.0285 | 0.1109 | 0.0216 | 0.1183 | 0.0000 | 0.0000 | 0.0016 | 0.0020 | 0.0024 | 0.0004 | 0.0199 | 0.0124 | 0.0749 | 0.0587 | 0.1204 | 0.0974 | 0.0863 | 0.0733 | 0.1178 | 0.1060 | 0.5768 | 0.6498 | 0.0004 | 0.0009 | 0.0008 | 0.0023 | 0.0046 | 0.0072 | 0.0347 | 0.0432 | 0.1206 | 0.1292 | 0.1583 | 0.1567 | 0.0946 | 0.1094 | 0.1389 | 0.1531 | 0.4472 | 0.3980 | 0.0010 | 0.0016 | 0.0035 | 0.0247 | 0.0958 | 0.1380 | 0.0986 | 0.1415 | 0.4954 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 590 | 585 | 6499 | 12657 | 474.1 | 105.05 | 39.01 | 84.66 | 344 | 379 | 410 | 438 | 465 | 494 | 525 | 566 | 619 | 0.0658 | 833 | 0.436 | 85.09 | 24.33 | 2 | 0.0495 | 322 | 0.0005 | 98.02 | 7.849 | 0.1181 | 235821.0 | 123000000 | 66600000000 | 37500000000000 | 0.4186 | 0.2373 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0081 | 0.0002 | 0.0234 | 0.0021 | 0.0846 | 0.0185 | 0.1319 | 0.0439 | 0.1403 | 0.0446 | 0.1617 | 0.0662 | 0.4487 | 0.8246 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0075 | 0.0012 | 0.0359 | 0.0131 | 0.0667 | 0.0284 | 0.0658 | 0.0201 | 0.0850 | 0.0339 | 0.7372 | 0.9033 | 0.0024 | 0.0066 | 0.0072 | 0.0197 | 0.0168 | 0.0623 | 0.0455 | 0.1049 | 0.1310 | 0.2164 | 0.1566 | 0.1934 | 0.1054 | 0.1213 | 0.1454 | 0.1016 | 0.3898 | 0.1738 | 0.0007 | 0.0013 | 0.0093 | 0.0251 | 0.0753 | 0.1245 | 0.0951 | 0.1176 | 0.5510 | 8 | 10 | 11 | 13 | 14 | 16 | 20 | 32 | 83 | 0.3458 | 2.93 | 2.365 | 0.7930 | 8689.1 | 4200000 | 2620000000 | 1850000000000 | 0.5811 | 0.1080 | 0.0885 | 0.0104 | 0.2543 | 0.0345 | 0.2812 | 0.1127 | 0.1438 | 0.1577 | 0.1011 | 0.2117 | 0.0616 | 0.1837 | 0.0442 | 0.1186 | 0.0221 | 0.0840 | 0.0032 | 0.0866 | 0.0012 | 0.0043 | 0.0039 | 0.0074 | 0.0075 | 0.0086 | 0.0365 | 0.0296 | 0.0821 | 0.0734 | 0.1147 | 0.0932 | 0.0825 | 0.0839 | 0.1222 | 0.1175 | 0.5495 | 0.5820 | 0.0016 | 0.0023 | 0.0031 | 0.0012 | 0.0047 | 0.0059 | 0.0350 | 0.0457 | 0.0957 | 0.1019 | 0.1479 | 0.1547 | 0.0883 | 0.0873 | 0.1181 | 0.1131 | 0.5055 | 0.4880 | 0.0009 | 0.0059 | 0.0054 | 0.0345 | 0.0917 | 0.1226 | 0.0903 | 0.1207 | 0.5279 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 559 | 324 | 5411 | 13979 | 127.3 | 31.31 | 130.32 | 107.34 | 89 | 100 | 109 | 117 | 124 | 132 | 141 | 151 | 168 | 0.0763 | 1067 | 1.014 | 110.37 | 33.29 | 4 | 0.0521 | 282 | 0.0023 | 18.78 | 6.376 | 0.2715 | 17190.0 | 2460000 | 372000000 | 59300000000 | 0.4432 | 0.2029 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0080 | 0.0014 | 0.0234 | 0.0043 | 0.0765 | 0.0204 | 0.1540 | 0.0553 | 0.1534 | 0.0488 | 0.1918 | 0.0784 | 0.3919 | 0.7915 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0077 | 0.0019 | 0.0329 | 0.0131 | 0.0659 | 0.0324 | 0.0624 | 0.0240 | 0.0845 | 0.0388 | 0.7452 | 0.8896 | 0.0068 | 0.0157 | 0.0087 | 0.0105 | 0.0243 | 0.0393 | 0.0816 | 0.0785 | 0.1516 | 0.1387 | 0.1642 | 0.2042 | 0.1127 | 0.1230 | 0.1399 | 0.1728 | 0.3100 | 0.2173 | 0.0012 | 0.0027 | 0.0054 | 0.0287 | 0.0794 | 0.1239 | 0.1084 | 0.1328 | 0.5174 | 28 | 45 | 62 | 81 | 100 | 125 | 156 | 198 | 271 | 0.0030 | 34.90 | 6.603 | 0.3130 | 28505.8 | 8880000 | 3530000000 | 1650000000000 | 0.5202 | 0.1472 | 0.0186 | 0.0011 | 0.0727 | 0.0086 | 0.1643 | 0.0338 | 0.1423 | 0.0684 | 0.1790 | 0.1246 | 0.1651 | 0.1717 | 0.1245 | 0.1441 | 0.0808 | 0.1616 | 0.0530 | 0.2861 | 0.0010 | 0.0005 | 0.0022 | 0.0019 | 0.0066 | 0.0044 | 0.0196 | 0.0131 | 0.0583 | 0.0437 | 0.1079 | 0.0808 | 0.0793 | 0.0712 | 0.1135 | 0.0987 | 0.6115 | 0.6857 | 0.0021 | 0.0027 | 0.0062 | 0.0046 | 0.0119 | 0.0161 | 0.0307 | 0.0402 | 0.0858 | 0.1010 | 0.1424 | 0.1586 | 0.1108 | 0.1077 | 0.1350 | 0.1324 | 0.4750 | 0.4367 | 0.0015 | 0.0050 | 0.0110 | 0.0224 | 0.0660 | 0.1195 | 0.1011 | 0.1256 | 0.5478 | |||
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 219 | 745 | 5417 | 7682 | 459.9 | 105.22 | 163.49 | 154.87 | 337 | 370 | 397 | 421 | 446 | 473 | 502 | 541 | 606 | 0.1009 | 775 | 0.952 | 103.82 | 28.00 | 1 | 0.0462 | 250 | 0.0007 | 65.25 | 7.472 | 0.1512 | 222541.0 | 113000000 | 60600000000 | 34000000000000 | 0.4352 | 0.2219 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0012 | 0.0002 | 0.0160 | 0.0018 | 0.0690 | 0.0207 | 0.1406 | 0.0417 | 0.1432 | 0.0435 | 0.1788 | 0.0688 | 0.4498 | 0.8231 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0073 | 0.0006 | 0.0381 | 0.0131 | 0.0709 | 0.0252 | 0.0628 | 0.0204 | 0.0986 | 0.0385 | 0.7212 | 0.9023 | 0.0061 | 0.0059 | 0.0163 | 0.0088 | 0.0132 | 0.0147 | 0.0499 | 0.1003 | 0.0957 | 0.1504 | 0.1232 | 0.1681 | 0.0896 | 0.1386 | 0.0998 | 0.1534 | 0.5061 | 0.2596 | 0.0016 | 0.0041 | 0.0086 | 0.0345 | 0.0858 | 0.1248 | 0.0998 | 0.1281 | 0.5127 | 16 | 24 | 47 | 80 | 120 | 162 | 209 | 275 | 401 | 0.0119 | 39.04 | 6.336 | 0.3337 | 50710.0 | 20800000 | 10000000000 | 5380000000000 | 0.5608 | 0.1109 | 0.0360 | 0.0009 | 0.1274 | 0.0147 | 0.1801 | 0.0477 | 0.1670 | 0.1198 | 0.1511 | 0.1590 | 0.1292 | 0.1862 | 0.1002 | 0.1203 | 0.0712 | 0.1323 | 0.0378 | 0.2192 | 0.0008 | 0.0002 | 0.0011 | 0.0005 | 0.0016 | 0.0021 | 0.0153 | 0.0143 | 0.0629 | 0.0509 | 0.1018 | 0.0835 | 0.0862 | 0.0685 | 0.1314 | 0.1042 | 0.5988 | 0.6757 | 0.0020 | 0.0020 | 0.0016 | 0.0045 | 0.0115 | 0.0109 | 0.0262 | 0.0377 | 0.0994 | 0.0942 | 0.1224 | 0.1413 | 0.0970 | 0.0932 | 0.1431 | 0.1413 | 0.4968 | 0.4750 | 0.0000 | 0.0010 | 0.0056 | 0.0203 | 0.0811 | 0.1353 | 0.0889 | 0.1366 | 0.5312 | |||
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 395 | 643 | 5110 | 12647 | 411.8 | 82.88 | 98.24 | 223.44 | 296 | 332 | 362 | 387 | 413 | 442 | 469 | 492 | 516 | 0.0659 | 833 | 1.130 | 86.12 | 29.43 | 1 | 0.0421 | 215 | 0.0017 | 11.85 | 6.634 | 0.3156 | 176415.0 | 78200000 | 35700000000 | 16700000000000 | 0.4107 | 0.2254 | 0.0009 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0000 | 0.0133 | 0.0006 | 0.0344 | 0.0142 | 0.0667 | 0.0259 | 0.0689 | 0.0150 | 0.0910 | 0.0273 | 0.7153 | 0.9170 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0027 | 0.0000 | 0.0046 | 0.0006 | 0.0126 | 0.0131 | 0.0239 | 0.0224 | 0.0220 | 0.0115 | 0.0305 | 0.0206 | 0.9023 | 0.9318 | 0.0041 | 0.0000 | 0.0072 | 0.1290 | 0.0103 | 0.1935 | 0.0351 | 0.1290 | 0.0784 | 0.2258 | 0.0991 | 0.2258 | 0.0877 | 0.0645 | 0.1290 | 0.0323 | 0.5490 | 0.0000 | 0.0004 | 0.0043 | 0.0031 | 0.0105 | 0.0233 | 0.0361 | 0.0415 | 0.0562 | 0.8247 | 7 | 8 | 10 | 11 | 13 | 16 | 30 | 87 | 318 | 0.2398 | 18.28 | 3.252 | 0.6811 | 59570.0 | 56500000 | 65600000000 | 86800000000000 | 0.3448 | 0.2408 | 0.0274 | 0.0023 | 0.1471 | 0.0150 | 0.2893 | 0.0495 | 0.1845 | 0.1164 | 0.1621 | 0.2085 | 0.0998 | 0.2385 | 0.0299 | 0.1336 | 0.0324 | 0.1083 | 0.0274 | 0.1279 | 0.0000 | 0.0007 | 0.0004 | 0.0007 | 0.0015 | 0.0020 | 0.0091 | 0.0078 | 0.0380 | 0.0346 | 0.0673 | 0.0620 | 0.0395 | 0.0400 | 0.0589 | 0.0491 | 0.7852 | 0.8032 | 0.0009 | 0.0005 | 0.0040 | 0.0010 | 0.0040 | 0.0024 | 0.0094 | 0.0086 | 0.0395 | 0.0427 | 0.0686 | 0.0734 | 0.0413 | 0.0504 | 0.0659 | 0.0705 | 0.7663 | 0.7505 | 0.0004 | 0.0013 | 0.0042 | 0.0129 | 0.0400 | 0.0642 | 0.0396 | 0.0554 | 0.7821 | |||
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 787 | 786 | 14112 | 32367 | 245.5 | 77.16 | 146.77 | 228.26 | 156 | 185 | 205 | 221 | 237 | 254 | 274 | 301 | 345 | 0.0488 | 1581 | 0.669 | 148.12 | 27.73 | 3 | 0.0257 | 363 | 0.0006 | 60.19 | 7.782 | 0.1687 | 66225.0 | 19500000 | 6230000000 | 2150000000000 | 0.4164 | 0.2099 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0068 | 0.0005 | 0.0211 | 0.0043 | 0.0673 | 0.0249 | 0.1414 | 0.0502 | 0.1309 | 0.0527 | 0.1587 | 0.0666 | 0.4724 | 0.8007 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0003 | 0.0074 | 0.0026 | 0.0218 | 0.0131 | 0.0526 | 0.0251 | 0.0492 | 0.0237 | 0.0741 | 0.0308 | 0.7916 | 0.9043 | 0.0010 | 0.0021 | 0.0033 | 0.0076 | 0.0118 | 0.0125 | 0.0393 | 0.0569 | 0.1035 | 0.1090 | 0.1432 | 0.1444 | 0.0996 | 0.0938 | 0.1288 | 0.1146 | 0.4695 | 0.4590 | 0.0005 | 0.0024 | 0.0074 | 0.0199 | 0.0565 | 0.1073 | 0.0842 | 0.1154 | 0.6063 | 13 | 15 | 17 | 22 | 34 | 66 | 132 | 244 | 448 | 0.0654 | 39.84 | 4.972 | 0.5439 | 73640.4 | 55300000 | 50400000000 | 51700000000000 | 0.5011 | 0.1602 | 0.0623 | 0.0031 | 0.2185 | 0.0242 | 0.2928 | 0.1386 | 0.1538 | 0.1668 | 0.1059 | 0.2014 | 0.0738 | 0.1699 | 0.0455 | 0.1175 | 0.0254 | 0.0808 | 0.0220 | 0.0977 | 0.0000 | 0.0003 | 0.0009 | 0.0002 | 0.0020 | 0.0009 | 0.0125 | 0.0097 | 0.0604 | 0.0529 | 0.0922 | 0.0798 | 0.0683 | 0.0642 | 0.1028 | 0.0895 | 0.6609 | 0.7026 | 0.0001 | 0.0004 | 0.0013 | 0.0019 | 0.0031 | 0.0054 | 0.0184 | 0.0221 | 0.0771 | 0.0786 | 0.1154 | 0.1217 | 0.0827 | 0.0911 | 0.1160 | 0.1245 | 0.5858 | 0.5543 | 0.0004 | 0.0009 | 0.0021 | 0.0159 | 0.0682 | 0.1066 | 0.0762 | 0.1087 | 0.6210 | |||
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 627 | 9507 | 15770 | 172.7 | 40.39 | 150.51 | 142.96 | 124 | 138 | 148 | 159 | 169 | 180 | 192 | 205 | 226 | 0.0652 | 1028 | 0.252 | 178.21 | 38.29 | 2 | 0.0807 | 767 | 0.0013 | 30.28 | 6.953 | 0.2069 | 31455.3 | 6030000 | 1210000000 | 255000000000 | 0.4791 | 0.1735 | 0.0005 | 0.0001 | 0.0012 | 0.0000 | 0.0054 | 0.0005 | 0.0209 | 0.0019 | 0.0790 | 0.0197 | 0.1482 | 0.0402 | 0.1609 | 0.0520 | 0.1854 | 0.0737 | 0.3985 | 0.8119 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0001 | 0.0082 | 0.0004 | 0.0356 | 0.0131 | 0.0592 | 0.0224 | 0.0625 | 0.0227 | 0.0860 | 0.0360 | 0.7450 | 0.9053 | 0.0072 | 0.0075 | 0.0078 | 0.0226 | 0.0245 | 0.0395 | 0.0686 | 0.1598 | 0.1421 | 0.1692 | 0.1633 | 0.1805 | 0.1165 | 0.1297 | 0.1427 | 0.1147 | 0.3272 | 0.1767 | 0.0011 | 0.0022 | 0.0101 | 0.0314 | 0.0686 | 0.1188 | 0.1000 | 0.1331 | 0.5347 | 15 | 26 | 47 | 75 | 109 | 150 | 195 | 249 | 346 | 0.0111 | 36.23 | 6.317 | 0.3622 | 43089.9 | 16900000 | 8150000000 | 4520000000000 | 0.5500 | 0.1433 | 0.0300 | 0.0027 | 0.1203 | 0.0089 | 0.2106 | 0.0533 | 0.1413 | 0.1064 | 0.1498 | 0.1689 | 0.1341 | 0.1813 | 0.0903 | 0.1371 | 0.0662 | 0.1320 | 0.0577 | 0.2093 | 0.0005 | 0.0010 | 0.0013 | 0.0013 | 0.0051 | 0.0033 | 0.0142 | 0.0094 | 0.0556 | 0.0503 | 0.0990 | 0.0768 | 0.0770 | 0.0661 | 0.1045 | 0.0926 | 0.6428 | 0.6991 | 0.0008 | 0.0021 | 0.0025 | 0.0062 | 0.0081 | 0.0129 | 0.0272 | 0.0348 | 0.0805 | 0.0881 | 0.1303 | 0.1407 | 0.0956 | 0.1050 | 0.1222 | 0.1264 | 0.5327 | 0.4839 | 0.0003 | 0.0032 | 0.0054 | 0.0167 | 0.0715 | 0.1122 | 0.0858 | 0.1157 | 0.5891 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 680 | 551 | 5987 | 6093 | 134.6 | 38.08 | 176.05 | 235.22 | 92 | 104 | 113 | 122 | 129 | 138 | 148 | 161 | 182 | 0.1188 | 724 | 1.000 | 95.60 | 29.27 | 1 | 0.0403 | 241 | 0.0020 | 24.09 | 6.532 | 0.2581 | 19556.5 | 3090000 | 540000000 | 105000000000 | 0.4491 | 0.2026 | 0.0006 | 0.0000 | 0.0035 | 0.0004 | 0.0088 | 0.0006 | 0.0253 | 0.0021 | 0.0823 | 0.0225 | 0.1531 | 0.0497 | 0.1611 | 0.0584 | 0.1743 | 0.0871 | 0.3909 | 0.7792 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0000 | 0.0090 | 0.0005 | 0.0374 | 0.0132 | 0.0593 | 0.0258 | 0.0654 | 0.0231 | 0.0842 | 0.0390 | 0.7408 | 0.8984 | 0.0009 | 0.0104 | 0.0128 | 0.0084 | 0.0239 | 0.0251 | 0.0632 | 0.0898 | 0.1376 | 0.1962 | 0.1709 | 0.1649 | 0.1043 | 0.1211 | 0.1564 | 0.1608 | 0.3299 | 0.2234 | 0.0023 | 0.0023 | 0.0095 | 0.0338 | 0.0834 | 0.1244 | 0.1085 | 0.1301 | 0.5059 | 10 | 11 | 13 | 16 | 34 | 115 | 229 | 352 | 553 | 0.1116 | 42.16 | 4.818 | 0.5374 | 86309.7 | 54700000 | 39600000000 | 31400000000000 | 0.5384 | 0.1532 | 0.0884 | 0.0052 | 0.2601 | 0.0551 | 0.2652 | 0.1627 | 0.1288 | 0.1890 | 0.0833 | 0.2008 | 0.0758 | 0.1444 | 0.0581 | 0.0866 | 0.0227 | 0.0735 | 0.0177 | 0.0827 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0020 | 0.0121 | 0.0068 | 0.0484 | 0.0419 | 0.0963 | 0.0971 | 0.0652 | 0.0532 | 0.0963 | 0.0789 | 0.6799 | 0.7201 | 0.0000 | 0.0006 | 0.0016 | 0.0017 | 0.0021 | 0.0058 | 0.0172 | 0.0221 | 0.0667 | 0.0813 | 0.1199 | 0.1371 | 0.0896 | 0.0936 | 0.1214 | 0.1174 | 0.5816 | 0.5404 | 0.0000 | 0.0014 | 0.0023 | 0.0136 | 0.0567 | 0.1068 | 0.0829 | 0.1036 | 0.6326 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1164 | 748 | 6717 | 22463 | 231.2 | 47.47 | 136.57 | 200.73 | 173 | 191 | 204 | 215 | 227 | 239 | 252 | 268 | 296 | 0.0526 | 1181 | 0.934 | 159.62 | 41.01 | 1 | 0.0582 | 391 | 0.0009 | 55.53 | 7.264 | 0.1600 | 55703.1 | 14000000 | 3650000000 | 990000000000 | 0.4604 | 0.1920 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0003 | 0.0127 | 0.0008 | 0.0689 | 0.0184 | 0.1261 | 0.0348 | 0.1510 | 0.0342 | 0.1834 | 0.0606 | 0.4552 | 0.8508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0001 | 0.0050 | 0.0003 | 0.0314 | 0.0132 | 0.0557 | 0.0204 | 0.0683 | 0.0150 | 0.0944 | 0.0288 | 0.7437 | 0.9222 | 0.0094 | 0.0220 | 0.0122 | 0.0293 | 0.0300 | 0.0549 | 0.0880 | 0.1172 | 0.1451 | 0.2125 | 0.1751 | 0.1978 | 0.1170 | 0.1026 | 0.1517 | 0.1172 | 0.2715 | 0.1465 | 0.0006 | 0.0029 | 0.0095 | 0.0350 | 0.1008 | 0.1316 | 0.1272 | 0.1459 | 0.4464 | 8 | 10 | 11 | 13 | 17 | 50 | 153 | 289 | 440 | 0.1678 | 32.49 | 4.522 | 0.5734 | 58941.1 | 34500000 | 24900000000 | 22000000000000 | 0.4912 | 0.1551 | 0.1222 | 0.0039 | 0.3163 | 0.0380 | 0.3182 | 0.2866 | 0.1251 | 0.2349 | 0.0660 | 0.1696 | 0.0394 | 0.1194 | 0.0089 | 0.0653 | 0.0039 | 0.0443 | 0.0000 | 0.0380 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0001 | 0.0002 | 0.0044 | 0.0063 | 0.0495 | 0.0387 | 0.0788 | 0.0683 | 0.0580 | 0.0512 | 0.1014 | 0.0836 | 0.7073 | 0.7515 | 0.0000 | 0.0003 | 0.0003 | 0.0005 | 0.0002 | 0.0016 | 0.0104 | 0.0097 | 0.0555 | 0.0675 | 0.1057 | 0.1099 | 0.0760 | 0.0890 | 0.1243 | 0.1280 | 0.6276 | 0.5934 | 0.0000 | 0.0006 | 0.0006 | 0.0083 | 0.0528 | 0.0884 | 0.0720 | 0.1141 | 0.6632 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 825 | 684 | 7651 | 20186 | 434.9 | 80.92 | 100.21 | 97.16 | 337 | 366 | 390 | 409 | 429 | 448 | 471 | 501 | 545 | 0.0502 | 1013 | 1.138 | 102.84 | 33.06 | 1 | 0.0322 | 246 | 0.0009 | 43.02 | 7.234 | 0.1788 | 195716.0 | 91000000 | 43700000000 | 21700000000000 | 0.4528 | 0.2044 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0003 | 0.0109 | 0.0004 | 0.0464 | 0.0156 | 0.1085 | 0.0248 | 0.1193 | 0.0267 | 0.1502 | 0.0416 | 0.5632 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0047 | 0.0004 | 0.0241 | 0.0132 | 0.0533 | 0.0176 | 0.0554 | 0.0141 | 0.0757 | 0.0217 | 0.7862 | 0.9330 | 0.0026 | 0.0221 | 0.0123 | 0.0608 | 0.0202 | 0.0663 | 0.0792 | 0.1381 | 0.1206 | 0.1547 | 0.1637 | 0.1381 | 0.1021 | 0.1105 | 0.1144 | 0.1050 | 0.3847 | 0.2044 | 0.0011 | 0.0050 | 0.0089 | 0.0319 | 0.0727 | 0.1248 | 0.1040 | 0.1262 | 0.5255 | 9 | 12 | 22 | 46 | 73 | 101 | 133 | 177 | 238 | 0.0261 | 11.79 | 5.435 | 0.4724 | 19482.1 | 5010000 | 1530000000 | 533000000000 | 0.4602 | 0.1900 | 0.0169 | 0.0009 | 0.0928 | 0.0052 | 0.1893 | 0.0424 | 0.1626 | 0.0894 | 0.1630 | 0.1492 | 0.1587 | 0.1861 | 0.0954 | 0.1402 | 0.0745 | 0.1464 | 0.0468 | 0.2402 | 0.0006 | 0.0001 | 0.0007 | 0.0006 | 0.0017 | 0.0015 | 0.0093 | 0.0072 | 0.0425 | 0.0340 | 0.0820 | 0.0612 | 0.0679 | 0.0521 | 0.0976 | 0.0811 | 0.6977 | 0.7621 | 0.0009 | 0.0007 | 0.0013 | 0.0023 | 0.0028 | 0.0042 | 0.0180 | 0.0214 | 0.0688 | 0.0820 | 0.1143 | 0.1324 | 0.0930 | 0.0958 | 0.1199 | 0.1291 | 0.5810 | 0.5321 | 0.0007 | 0.0011 | 0.0034 | 0.0138 | 0.0527 | 0.0963 | 0.0820 | 0.1141 | 0.6359 | |||
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 750 | 676 | 11146 | 21855 | 106.6 | 28.30 | 189.51 | 171.91 | 74 | 83 | 90 | 97 | 103 | 110 | 118 | 128 | 143 | 0.0573 | 1252 | 0.886 | 106.10 | 29.53 | 1 | 0.0241 | 269 | 0.0014 | 32.07 | 6.896 | 0.2173 | 12166.0 | 1490000 | 200000000 | 29600000000 | 0.4458 | 0.2114 | 0.0009 | 0.0000 | 0.0026 | 0.0003 | 0.0096 | 0.0013 | 0.0300 | 0.0038 | 0.0861 | 0.0213 | 0.1508 | 0.0508 | 0.1608 | 0.0587 | 0.1819 | 0.0839 | 0.3773 | 0.7799 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0039 | 0.0003 | 0.0101 | 0.0021 | 0.0393 | 0.0133 | 0.0634 | 0.0258 | 0.0685 | 0.0231 | 0.0980 | 0.0366 | 0.7155 | 0.8988 | 0.0018 | 0.0088 | 0.0088 | 0.0164 | 0.0226 | 0.0582 | 0.0647 | 0.1239 | 0.1317 | 0.2010 | 0.1714 | 0.1795 | 0.1183 | 0.1163 | 0.1423 | 0.1277 | 0.3383 | 0.1681 | 0.0014 | 0.0032 | 0.0116 | 0.0332 | 0.0812 | 0.1162 | 0.1018 | 0.1287 | 0.5226 | 16 | 35 | 67 | 103 | 142 | 190 | 249 | 320 | 433 | 0.0120 | 37.39 | 6.296 | 0.3650 | 65463.6 | 30100000 | 16600000000 | 10400000000000 | 0.5497 | 0.1277 | 0.0358 | 0.0017 | 0.1299 | 0.0109 | 0.2197 | 0.0768 | 0.1613 | 0.1097 | 0.1616 | 0.1610 | 0.1328 | 0.1855 | 0.0738 | 0.1385 | 0.0543 | 0.1308 | 0.0308 | 0.1851 | 0.0000 | 0.0000 | 0.0012 | 0.0012 | 0.0025 | 0.0022 | 0.0135 | 0.0090 | 0.0598 | 0.0462 | 0.1069 | 0.0836 | 0.0781 | 0.0656 | 0.1195 | 0.1003 | 0.6185 | 0.6919 | 0.0006 | 0.0002 | 0.0018 | 0.0023 | 0.0045 | 0.0088 | 0.0267 | 0.0326 | 0.0915 | 0.1031 | 0.1477 | 0.1742 | 0.1100 | 0.1208 | 0.1446 | 0.1560 | 0.4726 | 0.4020 | 0.0002 | 0.0008 | 0.0031 | 0.0184 | 0.0746 | 0.1276 | 0.0976 | 0.1359 | 0.5419 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1086 | 620 | 4452 | 3745 | 173.1 | 35.31 | 160.12 | 114.34 | 133 | 145 | 153 | 161 | 169 | 177 | 186 | 197 | 216 | 0.1522 | 570 | 1.194 | 77.34 | 28.86 | 1 | 0.0442 | 197 | 0.0021 | 21.97 | 6.469 | 0.2475 | 31225.1 | 5890000 | 1170000000 | 246000000000 | 0.3936 | 0.2497 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0002 | 0.0175 | 0.0012 | 0.0519 | 0.0169 | 0.1051 | 0.0386 | 0.1236 | 0.0286 | 0.1721 | 0.0435 | 0.5232 | 0.8710 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0100 | 0.0009 | 0.0257 | 0.0133 | 0.0524 | 0.0252 | 0.0561 | 0.0137 | 0.0820 | 0.0252 | 0.7704 | 0.9216 | 0.0032 | 0.0056 | 0.0323 | 0.0113 | 0.0258 | 0.0339 | 0.0855 | 0.0734 | 0.1403 | 0.1864 | 0.1645 | 0.2034 | 0.1339 | 0.0847 | 0.1339 | 0.1073 | 0.2806 | 0.2938 | 0.0020 | 0.0039 | 0.0158 | 0.0331 | 0.0805 | 0.1051 | 0.1111 | 0.1362 | 0.5123 | 40 | 68 | 87 | 108 | 131 | 156 | 189 | 244 | 330 | 0.0027 | 39.04 | 6.449 | 0.3029 | 38710.2 | 12200000 | 4630000000 | 1970000000000 | 0.4732 | 0.1655 | 0.0072 | 0.0025 | 0.0929 | 0.0144 | 0.1158 | 0.0439 | 0.1411 | 0.0640 | 0.1496 | 0.1193 | 0.1604 | 0.1532 | 0.1086 | 0.1293 | 0.0989 | 0.1494 | 0.1255 | 0.3239 | 0.0021 | 0.0012 | 0.0031 | 0.0032 | 0.0093 | 0.0057 | 0.0260 | 0.0114 | 0.0639 | 0.0584 | 0.1070 | 0.0852 | 0.0826 | 0.0697 | 0.1158 | 0.1010 | 0.5903 | 0.6642 | 0.0027 | 0.0011 | 0.0046 | 0.0057 | 0.0146 | 0.0137 | 0.0401 | 0.0538 | 0.0866 | 0.0985 | 0.1486 | 0.1546 | 0.0902 | 0.1168 | 0.1395 | 0.1730 | 0.4731 | 0.3826 | 0.0021 | 0.0041 | 0.0110 | 0.0336 | 0.0782 | 0.1221 | 0.0912 | 0.1276 | 0.5302 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 338 | 385 | 6192 | 19742 | 233.9 | 53.78 | 137.63 | 180.46 | 171 | 188 | 203 | 216 | 228 | 242 | 256 | 273 | 303 | 0.0555 | 1095 | 1.184 | 93.43 | 33.02 | 1 | 0.0363 | 225 | 0.0009 | 46.43 | 7.247 | 0.1652 | 57591.1 | 14900000 | 4100000000 | 1190000000000 | 0.3895 | 0.2646 | 0.0000 | 0.0000 | 0.0018 | 0.0002 | 0.0041 | 0.0002 | 0.0216 | 0.0019 | 0.0685 | 0.0188 | 0.1277 | 0.0445 | 0.1508 | 0.0419 | 0.1815 | 0.0664 | 0.4442 | 0.8263 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0002 | 0.0094 | 0.0011 | 0.0292 | 0.0133 | 0.0619 | 0.0277 | 0.0581 | 0.0198 | 0.0873 | 0.0284 | 0.7507 | 0.9093 | 0.0076 | 0.0147 | 0.0066 | 0.0265 | 0.0199 | 0.0265 | 0.0939 | 0.1088 | 0.1319 | 0.1559 | 0.1717 | 0.1706 | 0.1063 | 0.0971 | 0.1395 | 0.1294 | 0.3226 | 0.2706 | 0.0007 | 0.0025 | 0.0074 | 0.0298 | 0.0895 | 0.1288 | 0.1057 | 0.1541 | 0.4816 | 12 | 14 | 17 | 23 | 43 | 88 | 167 | 264 | 387 | 0.0461 | 28.23 | 5.244 | 0.4903 | 51505.6 | 27300000 | 17700000000 | 13300000000000 | 0.5436 | 0.1197 | 0.0589 | 0.0037 | 0.2135 | 0.0134 | 0.3305 | 0.1158 | 0.1622 | 0.1818 | 0.0910 | 0.2308 | 0.0773 | 0.1922 | 0.0344 | 0.1091 | 0.0245 | 0.0820 | 0.0077 | 0.0712 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0018 | 0.0016 | 0.0103 | 0.0074 | 0.0488 | 0.0426 | 0.0827 | 0.0744 | 0.0564 | 0.0488 | 0.0887 | 0.0770 | 0.7108 | 0.7471 | 0.0003 | 0.0002 | 0.0010 | 0.0013 | 0.0015 | 0.0013 | 0.0126 | 0.0158 | 0.0614 | 0.0710 | 0.1023 | 0.1142 | 0.0737 | 0.0805 | 0.1031 | 0.1182 | 0.6440 | 0.5975 | 0.0002 | 0.0003 | 0.0017 | 0.0124 | 0.0554 | 0.0907 | 0.0685 | 0.0965 | 0.6744 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 910 | 235 | 5650 | 9484 | 613.1 | 99.25 | 15.85 | 17.71 | 472 | 537 | 575 | 601 | 623 | 643 | 663 | 690 | 733 | 0.0777 | 737 | 0.760 | 87.05 | 15.26 | 1 | 0.0388 | 219 | 0.0011 | 30.87 | 7.107 | 0.2252 | 385716.0 | 248000000 | 163000000000 | 109000000000000 | 0.3922 | 0.2485 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0043 | 0.0007 | 0.0256 | 0.0133 | 0.0488 | 0.0204 | 0.0442 | 0.0136 | 0.0551 | 0.0226 | 0.8197 | 0.9294 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0007 | 0.0151 | 0.0133 | 0.0258 | 0.0204 | 0.0208 | 0.0122 | 0.0270 | 0.0190 | 0.9099 | 0.9344 | 0.0036 | 0.2000 | 0.0145 | 0.8000 | 0.0163 | 0.0000 | 0.0435 | 0.0000 | 0.0870 | 0.0000 | 0.1431 | 0.0000 | 0.0833 | 0.0000 | 0.1105 | 0.0000 | 0.4982 | 0.0000 | 0.0019 | 0.0019 | 0.0061 | 0.0129 | 0.0399 | 0.0633 | 0.0672 | 0.0987 | 0.7081 | 5 | 7 | 8 | 9 | 11 | 13 | 15 | 20 | 32 | 0.2512 | 0.44 | 1.751 | 0.7487 | 564.9 | 50306.4 | 9130000 | 2400000000 | 0.5918 | 0.0979 | 0.0534 | 0.0357 | 0.0820 | 0.0510 | 0.0996 | 0.0522 | 0.1245 | 0.0695 | 0.1572 | 0.0948 | 0.1789 | 0.1024 | 0.1727 | 0.1371 | 0.1011 | 0.1779 | 0.0306 | 0.2793 | 0.0244 | 0.0248 | 0.0307 | 0.0322 | 0.0359 | 0.0315 | 0.0432 | 0.0424 | 0.0663 | 0.0619 | 0.0788 | 0.0696 | 0.0772 | 0.0803 | 0.1043 | 0.1080 | 0.5391 | 0.5493 | 0.0219 | 0.0129 | 0.0172 | 0.0233 | 0.0256 | 0.0259 | 0.0339 | 0.0291 | 0.0516 | 0.0505 | 0.0793 | 0.0627 | 0.0652 | 0.0524 | 0.0814 | 0.0996 | 0.6239 | 0.6436 | 0.0286 | 0.0414 | 0.0352 | 0.0447 | 0.0521 | 0.0660 | 0.0663 | 0.1015 | 0.5642 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 571 | 922 | 4617 | 8322 | 491.0 | 95.75 | 198.40 | 274.48 | 372 | 405 | 431 | 459 | 485 | 511 | 541 | 573 | 621 | 0.0908 | 756 | 1.217 | 121.30 | 48.70 | 1 | 0.0682 | 315 | 0.0006 | 68.44 | 7.576 | 0.1426 | 250279.0 | 132000000 | 72100000000 | 40600000000000 | 0.4178 | 0.2313 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0025 | 0.0586 | 0.0169 | 0.1189 | 0.0373 | 0.1287 | 0.0263 | 0.1587 | 0.0443 | 0.5217 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0064 | 0.0011 | 0.0309 | 0.0133 | 0.0554 | 0.0279 | 0.0492 | 0.0168 | 0.0717 | 0.0251 | 0.7855 | 0.9157 | 0.0040 | 0.0000 | 0.0081 | 0.0000 | 0.0256 | 0.0000 | 0.0823 | 0.0000 | 0.1107 | 0.0000 | 0.1741 | 0.0000 | 0.1039 | 0.0000 | 0.1323 | 0.0000 | 0.3590 | 0.0000 | 0.0005 | 0.0023 | 0.0059 | 0.0244 | 0.0765 | 0.1199 | 0.0851 | 0.1231 | 0.5624 | 15 | 20 | 25 | 38 | 68 | 118 | 188 | 348 | 633 | 0.0340 | 31.16 | 5.359 | 0.5201 | 114691.0 | 92700000 | 87100000000 | 90400000000000 | 0.3987 | 0.2243 | 0.0214 | 0.0007 | 0.1193 | 0.0152 | 0.2370 | 0.0550 | 0.1330 | 0.0774 | 0.1361 | 0.1527 | 0.1055 | 0.2069 | 0.0826 | 0.1122 | 0.0841 | 0.1165 | 0.0810 | 0.2634 | 0.0004 | 0.0003 | 0.0029 | 0.0015 | 0.0022 | 0.0021 | 0.0122 | 0.0114 | 0.0561 | 0.0418 | 0.0820 | 0.0749 | 0.0557 | 0.0523 | 0.0805 | 0.0737 | 0.7080 | 0.7419 | 0.0005 | 0.0000 | 0.0014 | 0.0010 | 0.0056 | 0.0031 | 0.0118 | 0.0118 | 0.0592 | 0.0536 | 0.0870 | 0.1050 | 0.0602 | 0.0551 | 0.0827 | 0.0881 | 0.6916 | 0.6823 | 0.0008 | 0.0017 | 0.0033 | 0.0124 | 0.0541 | 0.0880 | 0.0570 | 0.0843 | 0.6985 |