High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 157 | 329 | | 1738 | 4874 | 829.9 | 218.86 | 12.72 | 6.17 | 545 | 606 | 672 | 746 | 818 | 889 | 972 | 1058 | 1144 | 0.0903 | 440 | 1.050 | 47.54 | 16.03 | 1 | 0.0702 | 122 | 0.0011 | 32.34 | 6.913 | 0.1942 | 736559.0 | 692000000 | 681000000000 | 695000000000000 | 0.3830 | 0.2470 | 0.0000 | 0.0006 | 0.0000 | 0.0006 | 0.0039 | 0.0013 | 0.0209 | 0.0071 | 0.0706 | 0.0292 | 0.1033 | 0.0565 | 0.0928 | 0.0435 | 0.1294 | 0.0617 | 0.5791 | 0.7994 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0057 | 0.0024 | 0.0283 | 0.0209 | 0.0404 | 0.0435 | 0.0323 | 0.0215 | 0.0477 | 0.0316 | 0.8448 | 0.8802 | 0.0021 | 0.0217 | 0.0042 | 0.0145 | 0.0064 | 0.0145 | 0.0169 | 0.0725 | 0.0360 | 0.0870 | 0.0636 | 0.0797 | 0.0487 | 0.1377 | 0.0805 | 0.2101 | 0.7415 | 0.3623 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0311 | 0.0587 | 0.0335 | 0.0467 | 0.8228 | 7 | 8 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 0.0061 | 22.32 | 5.502 | 0.2607 | 199.8 | 4679.1 | 209109 | 15400000 | 0.5319 | 0.1291 | 0.0389 | 0.0014 | 0.1029 | 0.0079 | 0.1520 | 0.0200 | 0.1856 | 0.0485 | 0.2128 | 0.0891 | 0.1653 | 0.1213 | 0.0976 | 0.2022 | 0.0368 | 0.2799 | 0.0080 | 0.2298 | 0.0185 | 0.0007 | 0.0406 | 0.0045 | 0.0564 | 0.0121 | 0.0554 | 0.0289 | 0.0716 | 0.0535 | 0.0848 | 0.0705 | 0.1039 | 0.1025 | 0.1729 | 0.1735 | 0.3959 | 0.5540 | 0.0744 | 0.1222 | 0.0666 | 0.1109 | 0.1055 | 0.1598 | 0.1038 | 0.1297 | 0.1176 | 0.1297 | 0.1272 | 0.1034 | 0.1375 | 0.1034 | 0.1280 | 0.0658 | 0.1393 | 0.0752 | 0.0362 | 0.0460 | 0.0596 | 0.0732 | 0.0779 | 0.1009 | 0.1300 | 0.2155 | 0.2606 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 550 | 588 | | 3961 | 12702 | 362.6 | 74.74 | 145.47 | 313.98 | 267 | 301 | 325 | 344 | 362 | 380 | 400 | 423 | 452 | 0.0624 | 793 | 1.103 | 133.51 | 42.58 | 1 | 0.0836 | 331 | 0.0009 | 60.00 | 7.202 | 0.1727 | 137032.0 | 53800000 | 22000000000 | 9300000000000 | 0.4189 | 0.2240 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0191 | 0.0008 | 0.0484 | 0.0174 | 0.0949 | 0.0441 | 0.1019 | 0.0284 | 0.1484 | 0.0412 | 0.5837 | 0.8681 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0008 | 0.0179 | 0.0148 | 0.0363 | 0.0309 | 0.0312 | 0.0140 | 0.0515 | 0.0197 | 0.8556 | 0.9198 | 0.0035 | 0.0177 | 0.0209 | 0.0088 | 0.0435 | 0.0796 | 0.1009 | 0.1504 | 0.1687 | 0.1770 | 0.1965 | 0.2566 | 0.1287 | 0.0442 | 0.1270 | 0.1150 | 0.2104 | 0.1504 | 0.0015 | 0.0025 | 0.0066 | 0.0207 | 0.0673 | 0.1037 | 0.0967 | 0.1463 | 0.5547 | 8 | 11 | 14 | 21 | 33 | 53 | 90 | 169 | 374 | 0.0996 | 33.81 | 4.438 | 0.6074 | 119740.0 | 178000000 | 330000000000 | 679000000000000 | 0.4919 | 0.1485 | 0.0193 | 0.0012 | 0.1035 | 0.0094 | 0.2190 | 0.0528 | 0.2154 | 0.0944 | 0.2106 | 0.1812 | 0.1408 | 0.2223 | 0.0590 | 0.1554 | 0.0217 | 0.1384 | 0.0108 | 0.1449 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0018 | 0.0021 | 0.0121 | 0.0100 | 0.0667 | 0.0554 | 0.1113 | 0.0915 | 0.0640 | 0.0610 | 0.0969 | 0.0879 | 0.6473 | 0.6909 | 0.0000 | 0.0005 | 0.0024 | 0.0064 | 0.0064 | 0.0055 | 0.0189 | 0.0132 | 0.0781 | 0.0783 | 0.1305 | 0.1429 | 0.0673 | 0.0660 | 0.0995 | 0.1051 | 0.5969 | 0.5822 | 0.0003 | 0.0007 | 0.0031 | 0.0146 | 0.0809 | 0.1122 | 0.0729 | 0.0983 | 0.6170 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1271 | 351 | | 4157 | 9898 | 475.9 | 89.44 | 163.26 | 251.77 | 360 | 394 | 423 | 449 | 475 | 498 | 524 | 554 | 594 | 0.0813 | 805 | 1.028 | 152.20 | 40.79 | 2 | 0.0871 | 362 | 0.0008 | 73.60 | 7.318 | 0.1483 | 234454.0 | 119000000 | 62600000000 | 33700000000000 | 0.4174 | 0.2233 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0017 | 0.0000 | 0.0196 | 0.0010 | 0.0716 | 0.0187 | 0.1191 | 0.0382 | 0.1160 | 0.0296 | 0.1725 | 0.0500 | 0.4981 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0069 | 0.0007 | 0.0343 | 0.0162 | 0.0480 | 0.0300 | 0.0474 | 0.0157 | 0.0809 | 0.0288 | 0.7811 | 0.9086 | 0.0000 | 0.0390 | 0.0204 | 0.0260 | 0.0471 | 0.1429 | 0.0973 | 0.2597 | 0.1476 | 0.2338 | 0.2057 | 0.1558 | 0.1350 | 0.0779 | 0.1162 | 0.0519 | 0.2308 | 0.0130 | 0.0010 | 0.0010 | 0.0048 | 0.0299 | 0.0676 | 0.1356 | 0.1236 | 0.1472 | 0.4894 | 7 | 10 | 13 | 22 | 39 | 75 | 136 | 293 | 547 | 0.0676 | 32.18 | 4.895 | 0.5343 | 90034.8 | 69000000 | 62100000000 | 62700000000000 | 0.5861 | 0.0893 | 0.0409 | 0.0025 | 0.1595 | 0.0187 | 0.2704 | 0.0934 | 0.2179 | 0.1214 | 0.1595 | 0.1766 | 0.0914 | 0.2054 | 0.0311 | 0.1350 | 0.0214 | 0.1180 | 0.0078 | 0.1290 | 0.0003 | 0.0003 | 0.0013 | 0.0017 | 0.0043 | 0.0049 | 0.0140 | 0.0129 | 0.0478 | 0.0466 | 0.0870 | 0.0765 | 0.0558 | 0.0552 | 0.0797 | 0.0797 | 0.7096 | 0.7222 | 0.0004 | 0.0000 | 0.0016 | 0.0017 | 0.0028 | 0.0043 | 0.0172 | 0.0170 | 0.0537 | 0.0679 | 0.1034 | 0.0909 | 0.0577 | 0.0635 | 0.0885 | 0.0905 | 0.6747 | 0.6642 | 0.0000 | 0.0026 | 0.0026 | 0.0125 | 0.0521 | 0.0922 | 0.0558 | 0.0845 | 0.6978 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 994 | 366 | | 5578 | 9502 | 439.0 | 109.23 | 7.27 | 7.81 | 292 | 342 | 380 | 410 | 440 | 471 | 499 | 532 | 577 | 0.0764 | 726 | 0.939 | 87.10 | 28.18 | 1 | 0.0446 | 249 | 0.0007 | 54.37 | 7.463 | 0.1610 | 204683.0 | 101000000 | 51800000000 | 27900000000000 | 0.4190 | 0.2212 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0035 | 0.0004 | 0.0227 | 0.0026 | 0.0796 | 0.0200 | 0.1332 | 0.0381 | 0.1486 | 0.0495 | 0.1674 | 0.0707 | 0.4438 | 0.8187 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0004 | 0.0055 | 0.0021 | 0.0249 | 0.0145 | 0.0386 | 0.0203 | 0.0420 | 0.0202 | 0.0598 | 0.0259 | 0.8277 | 0.9167 | 0.0025 | 0.0150 | 0.0083 | 0.0300 | 0.0108 | 0.0936 | 0.0717 | 0.1685 | 0.1350 | 0.1648 | 0.1983 | 0.1985 | 0.1250 | 0.0749 | 0.1433 | 0.0599 | 0.3050 | 0.1948 | 0.0011 | 0.0014 | 0.0018 | 0.0164 | 0.0513 | 0.0969 | 0.0840 | 0.1033 | 0.6439 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.3430 | 0.51 | 1.198 | 0.7294 | 113.9 | 6884.51 | 785459 | 106000000 | 0.5832 | 0.1225 | 0.0192 | 0.0019 | 0.0770 | 0.0156 | 0.1579 | 0.0462 | 0.2263 | 0.1039 | 0.2280 | 0.1979 | 0.1695 | 0.2473 | 0.0885 | 0.2176 | 0.0290 | 0.1308 | 0.0047 | 0.0389 | 0.0061 | 0.0001 | 0.0245 | 0.0052 | 0.0678 | 0.0214 | 0.1121 | 0.0524 | 0.1595 | 0.1246 | 0.1671 | 0.1799 | 0.1649 | 0.2137 | 0.1572 | 0.2103 | 0.1408 | 0.1925 | 0.1745 | 0.1950 | 0.1707 | 0.1376 | 0.1329 | 0.1217 | 0.1097 | 0.1088 | 0.0929 | 0.0945 | 0.0843 | 0.0801 | 0.0659 | 0.0748 | 0.0751 | 0.0786 | 0.0940 | 0.1088 | 0.0231 | 0.0695 | 0.1299 | 0.1560 | 0.1619 | 0.1493 | 0.1157 | 0.0965 | 0.0981 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 593 | 809 | | 9054 | 36760 | 386.6 | 78.38 | 181.80 | 168.48 | 283 | 319 | 345 | 368 | 389 | 408 | 428 | 453 | 485 | 0.0343 | 1261 | 1.172 | 117.32 | 46.07 | 2 | 0.0357 | 323 | 0.0013 | 28.99 | 6.930 | 0.2068 | 155613.0 | 64900000 | 28000000000 | 12400000000000 | 0.4514 | 0.1993 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0031 | 0.0000 | 0.0122 | 0.0006 | 0.0609 | 0.0126 | 0.1366 | 0.0323 | 0.1416 | 0.0335 | 0.1674 | 0.0533 | 0.4776 | 0.8677 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0025 | 0.0000 | 0.0256 | 0.0110 | 0.0577 | 0.0252 | 0.0556 | 0.0184 | 0.0717 | 0.0277 | 0.7858 | 0.9178 | 0.0076 | 0.0205 | 0.0124 | 0.1231 | 0.0275 | 0.0923 | 0.0927 | 0.1282 | 0.1683 | 0.1692 | 0.1999 | 0.1538 | 0.1484 | 0.0974 | 0.1374 | 0.1077 | 0.2060 | 0.1077 | 0.0006 | 0.0009 | 0.0039 | 0.0214 | 0.0744 | 0.1309 | 0.1084 | 0.1493 | 0.5102 | 20 | 40 | 70 | 101 | 134 | 175 | 226 | 293 | 410 | 0.0090 | 24.30 | 6.122 | 0.3733 | 61436.3 | 29700000 | 18600000000 | 14600000000000 | 0.4309 | 0.1918 | 0.0224 | 0.0007 | 0.1034 | 0.0058 | 0.2259 | 0.0487 | 0.1796 | 0.0900 | 0.1556 | 0.1611 | 0.1385 | 0.1955 | 0.0838 | 0.1496 | 0.0540 | 0.1427 | 0.0368 | 0.2058 | 0.0002 | 0.0003 | 0.0014 | 0.0006 | 0.0040 | 0.0027 | 0.0165 | 0.0104 | 0.0562 | 0.0443 | 0.1108 | 0.0905 | 0.0855 | 0.0719 | 0.1171 | 0.1021 | 0.6083 | 0.6773 | 0.0012 | 0.0016 | 0.0027 | 0.0043 | 0.0087 | 0.0124 | 0.0274 | 0.0393 | 0.0838 | 0.0961 | 0.1402 | 0.1499 | 0.1102 | 0.1133 | 0.1381 | 0.1378 | 0.4877 | 0.4453 | 0.0006 | 0.0015 | 0.0052 | 0.0174 | 0.0731 | 0.1259 | 0.1003 | 0.1286 | 0.5475 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 442 | 641 | | 7990 | 25118 | 501.3 | 88.04 | 166.84 | 265.28 | 388 | 427 | 453 | 476 | 498 | 523 | 548 | 577 | 617 | 0.0471 | 1183 | 1.180 | 95.02 | 43.97 | 2 | 0.0333 | 266 | 0.0018 | 18.67 | 6.558 | 0.2470 | 259095.0 | 138000000 | 75200000000 | 42100000000000 | 0.4349 | 0.2174 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0004 | 0.0081 | 0.0004 | 0.0446 | 0.0106 | 0.0956 | 0.0227 | 0.1034 | 0.0182 | 0.1448 | 0.0317 | 0.6006 | 0.9161 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0003 | 0.0024 | 0.0004 | 0.0209 | 0.0097 | 0.0427 | 0.0195 | 0.0421 | 0.0112 | 0.0628 | 0.0166 | 0.8279 | 0.9424 | 0.0064 | 0.0682 | 0.0091 | 0.0455 | 0.0320 | 0.0795 | 0.0970 | 0.1591 | 0.1473 | 0.2045 | 0.1802 | 0.1591 | 0.1180 | 0.0795 | 0.1455 | 0.0909 | 0.2644 | 0.1136 | 0.0005 | 0.0038 | 0.0054 | 0.0222 | 0.0749 | 0.1073 | 0.1055 | 0.1318 | 0.5485 | 10 | 11 | 14 | 16 | 23 | 59 | 162 | 310 | 534 | 0.1363 | 42.26 | 4.688 | 0.5832 | 98205.2 | 84400000 | 91600000000 | 119000000000000 | 0.4503 | 0.1832 | 0.0986 | 0.0041 | 0.2120 | 0.0293 | 0.2896 | 0.1678 | 0.1638 | 0.1659 | 0.1033 | 0.2136 | 0.0800 | 0.1794 | 0.0287 | 0.0875 | 0.0194 | 0.0736 | 0.0047 | 0.0788 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0008 | 0.0081 | 0.0047 | 0.0452 | 0.0417 | 0.0840 | 0.0727 | 0.0594 | 0.0422 | 0.0840 | 0.0743 | 0.7185 | 0.7635 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0024 | 0.0121 | 0.0159 | 0.0604 | 0.0675 | 0.1040 | 0.1154 | 0.0752 | 0.0819 | 0.1097 | 0.1185 | 0.6378 | 0.5984 | 0.0000 | 0.0001 | 0.0012 | 0.0086 | 0.0549 | 0.0904 | 0.0693 | 0.0991 | 0.6764 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 786 | 723 | | 4403 | 10505 | 156.8 | 37.21 | 158.32 | 156.07 | 111 | 125 | 136 | 145 | 154 | 163 | 173 | 187 | 207 | 0.0730 | 767 | 1.082 | 105.15 | 39.01 | 1 | 0.0620 | 273 | 0.0017 | 27.23 | 6.665 | 0.2280 | 25980.4 | 4530000 | 831000000 | 159000000000 | 0.4286 | 0.2358 | 0.0007 | 0.0000 | 0.0045 | 0.0003 | 0.0138 | 0.0018 | 0.0302 | 0.0040 | 0.0832 | 0.0260 | 0.1542 | 0.0510 | 0.1486 | 0.0545 | 0.1725 | 0.0808 | 0.3923 | 0.7817 | 0.0000 | 0.0000 | 0.0009 | 0.0002 | 0.0009 | 0.0002 | 0.0068 | 0.0009 | 0.0392 | 0.0176 | 0.0717 | 0.0309 | 0.0697 | 0.0248 | 0.0958 | 0.0405 | 0.7151 | 0.8849 | 0.0024 | 0.0182 | 0.0155 | 0.0146 | 0.0274 | 0.0474 | 0.0764 | 0.1314 | 0.1372 | 0.1788 | 0.2076 | 0.2336 | 0.1313 | 0.0985 | 0.1396 | 0.1314 | 0.2625 | 0.1460 | 0.0024 | 0.0015 | 0.0068 | 0.0336 | 0.0973 | 0.1357 | 0.1051 | 0.1367 | 0.4810 | 15 | 27 | 45 | 75 | 110 | 150 | 199 | 265 | 380 | 0.0051 | 65.67 | 6.760 | 0.3104 | 49420.1 | 21200000 | 11000000000 | 6460000000000 | 0.5076 | 0.1389 | 0.0172 | 0.0010 | 0.0968 | 0.0078 | 0.2177 | 0.0413 | 0.1765 | 0.0889 | 0.1820 | 0.1633 | 0.1360 | 0.1965 | 0.0859 | 0.1508 | 0.0522 | 0.1403 | 0.0357 | 0.2100 | 0.0006 | 0.0000 | 0.0015 | 0.0009 | 0.0038 | 0.0042 | 0.0125 | 0.0116 | 0.0563 | 0.0446 | 0.0987 | 0.0767 | 0.0747 | 0.0616 | 0.1081 | 0.0892 | 0.6439 | 0.7113 | 0.0009 | 0.0015 | 0.0030 | 0.0036 | 0.0093 | 0.0109 | 0.0246 | 0.0318 | 0.0818 | 0.0982 | 0.1325 | 0.1383 | 0.0971 | 0.0985 | 0.1250 | 0.1438 | 0.5259 | 0.4734 | 0.0002 | 0.0017 | 0.0057 | 0.0214 | 0.0664 | 0.1176 | 0.0927 | 0.1161 | 0.5782 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 730 | 546 | | 7063 | 16463 | 184.9 | 40.76 | 99.35 | 87.89 | 137 | 151 | 161 | 169 | 179 | 190 | 202 | 219 | 240 | 0.0580 | 955 | 0.941 | 64.47 | 21.02 | 1 | 0.0239 | 169 | 0.0014 | 32.05 | 6.883 | 0.2025 | 35864.6 | 7300000 | 1560000000 | 348000000000 | 0.4301 | 0.2260 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0000 | 0.0175 | 0.0003 | 0.0785 | 0.0161 | 0.1523 | 0.0437 | 0.1574 | 0.0461 | 0.1936 | 0.0763 | 0.3963 | 0.8174 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0003 | 0.0317 | 0.0110 | 0.0693 | 0.0226 | 0.0664 | 0.0177 | 0.0909 | 0.0300 | 0.7338 | 0.9185 | 0.0054 | 0.0134 | 0.0069 | 0.0214 | 0.0239 | 0.0456 | 0.0677 | 0.1877 | 0.1524 | 0.2091 | 0.1963 | 0.1743 | 0.1301 | 0.1072 | 0.1617 | 0.1099 | 0.2556 | 0.1314 | 0.0009 | 0.0041 | 0.0135 | 0.0340 | 0.0810 | 0.1216 | 0.1141 | 0.1377 | 0.4931 | 13 | 22 | 36 | 53 | 73 | 98 | 131 | 169 | 224 | 0.0086 | 26.48 | 6.137 | 0.3816 | 17595.6 | 4190000 | 1210000000 | 411000000000 | 0.4596 | 0.1971 | 0.0237 | 0.0019 | 0.1194 | 0.0081 | 0.2469 | 0.0504 | 0.1843 | 0.1053 | 0.1708 | 0.1723 | 0.1252 | 0.1953 | 0.0725 | 0.1462 | 0.0367 | 0.1457 | 0.0206 | 0.1747 | 0.0004 | 0.0003 | 0.0021 | 0.0017 | 0.0031 | 0.0027 | 0.0125 | 0.0104 | 0.0556 | 0.0435 | 0.0954 | 0.0686 | 0.0762 | 0.0660 | 0.1107 | 0.0934 | 0.6440 | 0.7133 | 0.0004 | 0.0007 | 0.0015 | 0.0031 | 0.0060 | 0.0094 | 0.0218 | 0.0307 | 0.0828 | 0.1016 | 0.1359 | 0.1542 | 0.1068 | 0.1143 | 0.1359 | 0.1477 | 0.5090 | 0.4384 | 0.0005 | 0.0005 | 0.0038 | 0.0189 | 0.0670 | 0.1146 | 0.0919 | 0.1238 | 0.5791 | ||
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 289 | 493 | | 6798 | 23833 | 396.9 | 72.62 | 122.22 | 112.72 | 305 | 332 | 353 | 372 | 393 | 413 | 434 | 460 | 496 | 0.0457 | 1090 | 1.062 | 97.45 | 34.93 | 1 | 0.0374 | 254 | 0.0017 | 19.12 | 6.637 | 0.2476 | 162807.0 | 68900000 | 30000000000 | 13500000000000 | 0.3895 | 0.2520 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0023 | 0.0005 | 0.0107 | 0.0006 | 0.0469 | 0.0131 | 0.0916 | 0.0269 | 0.1033 | 0.0220 | 0.1432 | 0.0346 | 0.6015 | 0.9022 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0009 | 0.0003 | 0.0043 | 0.0003 | 0.0197 | 0.0111 | 0.0380 | 0.0209 | 0.0404 | 0.0105 | 0.0584 | 0.0164 | 0.8383 | 0.9404 | 0.0080 | 0.0227 | 0.0130 | 0.0455 | 0.0260 | 0.1136 | 0.0721 | 0.1212 | 0.1321 | 0.2045 | 0.1922 | 0.1515 | 0.1251 | 0.0985 | 0.1512 | 0.1061 | 0.2803 | 0.1364 | 0.0006 | 0.0018 | 0.0076 | 0.0223 | 0.0572 | 0.1036 | 0.0899 | 0.1253 | 0.5917 | 13 | 21 | 38 | 64 | 93 | 125 | 160 | 203 | 274 | 0.0273 | 9.30 | 5.190 | 0.4969 | 27642.2 | 8480000 | 3190000000 | 1400000000000 | 0.4768 | 0.1673 | 0.0272 | 0.0014 | 0.1103 | 0.0069 | 0.2030 | 0.0512 | 0.1793 | 0.1036 | 0.1586 | 0.1664 | 0.1277 | 0.1784 | 0.0836 | 0.1457 | 0.0699 | 0.1463 | 0.0404 | 0.2001 | 0.0004 | 0.0001 | 0.0012 | 0.0008 | 0.0030 | 0.0025 | 0.0136 | 0.0101 | 0.0526 | 0.0452 | 0.0989 | 0.0755 | 0.0730 | 0.0660 | 0.1124 | 0.0959 | 0.6447 | 0.7039 | 0.0012 | 0.0020 | 0.0031 | 0.0065 | 0.0092 | 0.0131 | 0.0290 | 0.0361 | 0.0788 | 0.0934 | 0.1280 | 0.1326 | 0.0965 | 0.1068 | 0.1320 | 0.1384 | 0.5220 | 0.4711 | 0.0005 | 0.0012 | 0.0038 | 0.0208 | 0.0676 | 0.1100 | 0.0939 | 0.1245 | 0.5777 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 899 | 757 | | 8961 | 31826 | 259.4 | 53.09 | 114.61 | 165.16 | 194 | 214 | 228 | 242 | 255 | 268 | 283 | 301 | 329 | 0.0403 | 1284 | 0.981 | 97.80 | 29.12 | 1 | 0.0280 | 251 | 0.0008 | 53.17 | 7.402 | 0.1637 | 70101.1 | 19700000 | 5780000000 | 1760000000000 | 0.4503 | 0.2063 | 0.0000 | 0.0001 | 0.0002 | 0.0000 | 0.0018 | 0.0004 | 0.0136 | 0.0014 | 0.0585 | 0.0160 | 0.1232 | 0.0320 | 0.1410 | 0.0288 | 0.1844 | 0.0435 | 0.4773 | 0.8778 | 0.0000 | 0.0001 | 0.0001 | 0.0000 | 0.0009 | 0.0001 | 0.0065 | 0.0007 | 0.0298 | 0.0108 | 0.0551 | 0.0198 | 0.0629 | 0.0145 | 0.0877 | 0.0191 | 0.7569 | 0.9349 | 0.0085 | 0.0127 | 0.0157 | 0.0127 | 0.0264 | 0.0204 | 0.0883 | 0.0992 | 0.1254 | 0.1476 | 0.1645 | 0.1730 | 0.1132 | 0.1374 | 0.1204 | 0.1527 | 0.3376 | 0.2443 | 0.0009 | 0.0040 | 0.0076 | 0.0301 | 0.0767 | 0.1303 | 0.1175 | 0.1407 | 0.4922 | 9 | 11 | 13 | 18 | 27 | 57 | 118 | 210 | 350 | 0.0979 | 28.78 | 4.781 | 0.5522 | 40414.6 | 20400000 | 12400000000 | 8610000000000 | 0.4405 | 0.1958 | 0.0756 | 0.0022 | 0.2289 | 0.0229 | 0.3344 | 0.1478 | 0.1476 | 0.1783 | 0.1070 | 0.2271 | 0.0571 | 0.1822 | 0.0288 | 0.0945 | 0.0118 | 0.0738 | 0.0087 | 0.0711 | 0.0002 | 0.0002 | 0.0001 | 0.0006 | 0.0010 | 0.0013 | 0.0093 | 0.0067 | 0.0501 | 0.0437 | 0.0928 | 0.0740 | 0.0638 | 0.0544 | 0.0943 | 0.0837 | 0.6883 | 0.7355 | 0.0002 | 0.0003 | 0.0008 | 0.0008 | 0.0015 | 0.0033 | 0.0136 | 0.0144 | 0.0615 | 0.0722 | 0.1163 | 0.1254 | 0.0773 | 0.0817 | 0.1147 | 0.1218 | 0.6140 | 0.5802 | 0.0004 | 0.0001 | 0.0011 | 0.0101 | 0.0596 | 0.1019 | 0.0697 | 0.1103 | 0.6467 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 355 | 746 | | 5178 | 14618 | 327.7 | 65.14 | 129.72 | 168.91 | 250 | 272 | 289 | 304 | 321 | 339 | 359 | 383 | 416 | 0.0483 | 706 | 1.223 | 132.20 | 48.33 | 1 | 0.0624 | 323 | 0.0006 | 79.47 | 7.577 | 0.1347 | 111643.0 | 39500000 | 14500000000 | 5500000000000 | 0.4016 | 0.2477 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0000 | 0.0124 | 0.0010 | 0.0615 | 0.0141 | 0.1154 | 0.0278 | 0.1391 | 0.0377 | 0.1708 | 0.0498 | 0.4976 | 0.8695 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0048 | 0.0006 | 0.0275 | 0.0103 | 0.0562 | 0.0177 | 0.0558 | 0.0168 | 0.0767 | 0.0242 | 0.7779 | 0.9305 | 0.0000 | 0.0057 | 0.0082 | 0.0341 | 0.0411 | 0.0625 | 0.0799 | 0.1591 | 0.1246 | 0.1932 | 0.1669 | 0.1648 | 0.1269 | 0.1193 | 0.1504 | 0.1307 | 0.3020 | 0.1307 | 0.0025 | 0.0038 | 0.0046 | 0.0302 | 0.0772 | 0.1234 | 0.1083 | 0.1318 | 0.5183 | 11 | 13 | 15 | 20 | 32 | 75 | 158 | 264 | 389 | 0.0486 | 32.17 | 5.262 | 0.4801 | 45355.6 | 21000000 | 11400000000 | 6870000000000 | 0.5030 | 0.1599 | 0.1206 | 0.0006 | 0.3330 | 0.0356 | 0.3146 | 0.2808 | 0.1079 | 0.2475 | 0.0769 | 0.1991 | 0.0321 | 0.1068 | 0.0115 | 0.0595 | 0.0023 | 0.0473 | 0.0011 | 0.0228 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0117 | 0.0095 | 0.0635 | 0.0521 | 0.0928 | 0.0937 | 0.0628 | 0.0577 | 0.1074 | 0.0968 | 0.6595 | 0.6891 | 0.0007 | 0.0007 | 0.0007 | 0.0015 | 0.0029 | 0.0020 | 0.0167 | 0.0162 | 0.0625 | 0.0729 | 0.1186 | 0.1226 | 0.0783 | 0.0896 | 0.1208 | 0.1300 | 0.5988 | 0.5646 | 0.0000 | 0.0002 | 0.0037 | 0.0165 | 0.0591 | 0.1021 | 0.0779 | 0.1118 | 0.6285 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 577 | 529 | | 6874 | 21430 | 274.4 | 54.77 | 116.67 | 134.04 | 206 | 226 | 242 | 256 | 270 | 284 | 301 | 322 | 348 | 0.0497 | 1066 | 0.952 | 129.08 | 32.53 | 1 | 0.0428 | 294 | 0.0008 | 54.60 | 7.392 | 0.1620 | 78288.9 | 23200000 | 7120000000 | 2260000000000 | 0.4124 | 0.2339 | 0.0007 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0002 | 0.0146 | 0.0009 | 0.0620 | 0.0167 | 0.1265 | 0.0357 | 0.1468 | 0.0339 | 0.1774 | 0.0560 | 0.4691 | 0.8567 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0052 | 0.0007 | 0.0245 | 0.0114 | 0.0505 | 0.0239 | 0.0545 | 0.0147 | 0.0759 | 0.0202 | 0.7879 | 0.9290 | 0.0068 | 0.0346 | 0.0101 | 0.0260 | 0.0245 | 0.1126 | 0.0785 | 0.1472 | 0.1647 | 0.2338 | 0.1976 | 0.1515 | 0.1309 | 0.1126 | 0.1512 | 0.1169 | 0.2356 | 0.0649 | 0.0012 | 0.0000 | 0.0080 | 0.0316 | 0.0807 | 0.1133 | 0.1072 | 0.1308 | 0.5272 | 10 | 13 | 16 | 28 | 55 | 99 | 154 | 222 | 315 | 0.0595 | 13.88 | 5.027 | 0.5286 | 31578.4 | 11600000 | 5190000000 | 2690000000000 | 0.5015 | 0.1536 | 0.0506 | 0.0016 | 0.2117 | 0.0180 | 0.3416 | 0.0886 | 0.1686 | 0.1769 | 0.1002 | 0.2501 | 0.0717 | 0.1846 | 0.0372 | 0.1200 | 0.0151 | 0.0904 | 0.0032 | 0.0698 | 0.0001 | 0.0000 | 0.0006 | 0.0005 | 0.0015 | 0.0008 | 0.0076 | 0.0083 | 0.0547 | 0.0435 | 0.0986 | 0.0770 | 0.0711 | 0.0601 | 0.1113 | 0.0927 | 0.6546 | 0.7171 | 0.0003 | 0.0007 | 0.0017 | 0.0016 | 0.0030 | 0.0034 | 0.0156 | 0.0219 | 0.0765 | 0.0905 | 0.1334 | 0.1420 | 0.0961 | 0.1062 | 0.1363 | 0.1430 | 0.5370 | 0.4906 | 0.0003 | 0.0010 | 0.0023 | 0.0117 | 0.0625 | 0.1168 | 0.0835 | 0.1295 | 0.5924 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 800 | 501 | | 13792 | 38751 | 266.6 | 61.19 | 169.99 | 277.73 | 192 | 219 | 237 | 253 | 267 | 281 | 297 | 317 | 345 | 0.0391 | 1515 | 0.913 | 98.60 | 27.17 | 6 | 0.0188 | 259 | 0.0012 | 28.43 | 7.043 | 0.2221 | 74836.6 | 21900000 | 6660000000 | 2090000000000 | 0.4163 | 0.2227 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0034 | 0.0004 | 0.0145 | 0.0030 | 0.0508 | 0.0123 | 0.1000 | 0.0294 | 0.1083 | 0.0291 | 0.1428 | 0.0414 | 0.5789 | 0.8845 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0051 | 0.0012 | 0.0181 | 0.0073 | 0.0381 | 0.0171 | 0.0415 | 0.0105 | 0.0570 | 0.0160 | 0.8387 | 0.9478 | 0.0032 | 0.0074 | 0.0083 | 0.0315 | 0.0221 | 0.0612 | 0.0437 | 0.1169 | 0.1095 | 0.1818 | 0.1536 | 0.1892 | 0.1312 | 0.1373 | 0.1276 | 0.1150 | 0.4009 | 0.1596 | 0.0001 | 0.0023 | 0.0069 | 0.0225 | 0.0520 | 0.0995 | 0.0920 | 0.1141 | 0.6107 | 11 | 14 | 16 | 21 | 32 | 62 | 139 | 285 | 553 | 0.1524 | 25.56 | 4.437 | 0.6078 | 106029.0 | 97600000 | 110000000000 | 141000000000000 | 0.3354 | 0.3305 | 0.0662 | 0.0027 | 0.2254 | 0.0240 | 0.2667 | 0.1419 | 0.1607 | 0.1818 | 0.1295 | 0.1818 | 0.0830 | 0.1829 | 0.0379 | 0.1071 | 0.0230 | 0.0916 | 0.0077 | 0.0861 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0035 | 0.0021 | 0.0193 | 0.0153 | 0.0582 | 0.0549 | 0.0728 | 0.0726 | 0.0478 | 0.0442 | 0.0766 | 0.0719 | 0.7205 | 0.7381 | 0.0006 | 0.0007 | 0.0019 | 0.0018 | 0.0059 | 0.0059 | 0.0221 | 0.0258 | 0.0548 | 0.0602 | 0.0841 | 0.0861 | 0.0579 | 0.0644 | 0.0867 | 0.0924 | 0.6859 | 0.6628 | 0.0003 | 0.0015 | 0.0047 | 0.0221 | 0.0559 | 0.0766 | 0.0542 | 0.0790 | 0.7058 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 619 | 317 | | 7410 | 29983 | 364.7 | 86.29 | 152.06 | 265.97 | 260 | 289 | 313 | 336 | 358 | 380 | 405 | 434 | 477 | 0.0351 | 1051 | 1.206 | 108.37 | 43.84 | 1 | 0.0379 | 281 | 0.0006 | 87.06 | 7.645 | 0.1436 | 140416.0 | 57000000 | 24300000000 | 10900000000000 | 0.4464 | 0.2073 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0086 | 0.0001 | 0.0271 | 0.0018 | 0.0873 | 0.0187 | 0.1534 | 0.0482 | 0.1532 | 0.0439 | 0.1846 | 0.0654 | 0.3836 | 0.8218 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0081 | 0.0003 | 0.0365 | 0.0110 | 0.0711 | 0.0286 | 0.0684 | 0.0204 | 0.0949 | 0.0311 | 0.7198 | 0.9085 | 0.0050 | 0.0092 | 0.0093 | 0.0297 | 0.0328 | 0.0343 | 0.0734 | 0.0847 | 0.1290 | 0.1533 | 0.1917 | 0.2197 | 0.1226 | 0.1327 | 0.1347 | 0.1373 | 0.3015 | 0.1991 | 0.0006 | 0.0026 | 0.0110 | 0.0266 | 0.0747 | 0.1389 | 0.1155 | 0.1259 | 0.5043 | 7 | 9 | 11 | 13 | 20 | 43 | 110 | 258 | 517 | 0.1512 | 39.36 | 4.482 | 0.5817 | 93855.6 | 84800000 | 94200000000 | 120000000000000 | 0.4152 | 0.1980 | 0.0734 | 0.0021 | 0.2052 | 0.0259 | 0.2539 | 0.1687 | 0.1640 | 0.1542 | 0.1373 | 0.1932 | 0.0879 | 0.1763 | 0.0480 | 0.1107 | 0.0165 | 0.0824 | 0.0137 | 0.0866 | 0.0000 | 0.0002 | 0.0007 | 0.0005 | 0.0021 | 0.0003 | 0.0100 | 0.0059 | 0.0491 | 0.0469 | 0.0856 | 0.0756 | 0.0537 | 0.0477 | 0.0753 | 0.0702 | 0.7236 | 0.7526 | 0.0003 | 0.0001 | 0.0018 | 0.0006 | 0.0017 | 0.0025 | 0.0090 | 0.0096 | 0.0589 | 0.0634 | 0.0991 | 0.1035 | 0.0632 | 0.0706 | 0.0877 | 0.0978 | 0.6783 | 0.6519 | 0.0001 | 0.0011 | 0.0020 | 0.0119 | 0.0542 | 0.0904 | 0.0605 | 0.0819 | 0.6977 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 895 | 228 | | 1426 | 7457 | 297.1 | 74.97 | 7.35 | 3.00 | 208 | 227 | 244 | 263 | 287 | 309 | 333 | 361 | 411 | 0.0758 | 565 | 1.060 | 52.39 | 17.09 | 1 | 0.0912 | 130 | 0.0050 | 5.81 | 5.550 | 0.3967 | 93879.8 | 31500000 | 11200000000 | 4160000000000 | 0.4025 | 0.2290 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0040 | 0.0008 | 0.0374 | 0.0038 | 0.0602 | 0.0369 | 0.0989 | 0.0638 | 0.0936 | 0.0430 | 0.1283 | 0.0692 | 0.5775 | 0.7809 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0171 | 0.0007 | 0.0286 | 0.0288 | 0.0390 | 0.0400 | 0.0448 | 0.0204 | 0.0524 | 0.0435 | 0.8171 | 0.8667 | 0.0000 | 0.0000 | 0.0066 | 0.0161 | 0.0166 | 0.0000 | 0.0364 | 0.0242 | 0.0530 | 0.1694 | 0.0629 | 0.1774 | 0.0927 | 0.0806 | 0.1060 | 0.2339 | 0.6258 | 0.2984 | 0.0016 | 0.0016 | 0.0109 | 0.0203 | 0.0422 | 0.0422 | 0.0703 | 0.0766 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 11 | 0.0171 | 9.64 | 4.604 | 0.3424 | 63.0 | 623.07 | 7074.44 | 91176.4 | 0.4927 | 0.1584 | 0.0077 | 0.0045 | 0.0406 | 0.0095 | 0.0981 | 0.0305 | 0.1678 | 0.0652 | 0.2278 | 0.1209 | 0.2100 | 0.1971 | 0.1593 | 0.2556 | 0.0768 | 0.2221 | 0.0121 | 0.0947 | 0.0010 | 0.0002 | 0.0055 | 0.0018 | 0.0185 | 0.0077 | 0.0480 | 0.0279 | 0.0854 | 0.0599 | 0.1434 | 0.1145 | 0.1875 | 0.1703 | 0.2216 | 0.2463 | 0.2890 | 0.3715 | 0.1040 | 0.1438 | 0.1361 | 0.1222 | 0.1301 | 0.0872 | 0.0853 | 0.0745 | 0.0895 | 0.1058 | 0.0811 | 0.0857 | 0.0956 | 0.0842 | 0.0923 | 0.1170 | 0.1860 | 0.1796 | 0.0135 | 0.0521 | 0.0974 | 0.1372 | 0.1573 | 0.1377 | 0.1213 | 0.1143 | 0.1691 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1118 | 571 | | 8114 | 11473 | 287.2 | 51.13 | 167.28 | 160.52 | 216 | 244 | 261 | 276 | 288 | 301 | 314 | 330 | 353 | 0.0825 | 946 | 0.972 | 44.55 | 15.65 | 1 | 0.0148 | 120 | 0.0020 | 14.93 | 6.529 | 0.2976 | 85117.2 | 26000000 | 8120000000 | 2600000000000 | 0.4373 | 0.2063 | 0.0005 | 0.0000 | 0.0015 | 0.0001 | 0.0027 | 0.0005 | 0.0121 | 0.0011 | 0.0320 | 0.0115 | 0.0585 | 0.0247 | 0.0605 | 0.0158 | 0.0827 | 0.0277 | 0.7495 | 0.9185 | 0.0003 | 0.0000 | 0.0003 | 0.0001 | 0.0010 | 0.0005 | 0.0049 | 0.0009 | 0.0130 | 0.0100 | 0.0228 | 0.0207 | 0.0186 | 0.0103 | 0.0277 | 0.0182 | 0.9114 | 0.9393 | 0.0075 | 0.0000 | 0.0197 | 0.0000 | 0.0254 | 0.0000 | 0.0630 | 0.0000 | 0.1006 | 0.0000 | 0.1410 | 0.0000 | 0.1194 | 0.0000 | 0.1391 | 0.0000 | 0.3844 | 0.0000 | 0.0017 | 0.0038 | 0.0094 | 0.0183 | 0.0428 | 0.0657 | 0.0729 | 0.0940 | 0.6914 | 14 | 20 | 33 | 56 | 109 | 178 | 247 | 321 | 407 | 0.0262 | 16.95 | 5.600 | 0.4608 | 53749.5 | 21300000 | 9500000000 | 4610000000000 | 0.5388 | 0.1195 | 0.0204 | 0.0036 | 0.0844 | 0.0071 | 0.2027 | 0.0554 | 0.2124 | 0.0996 | 0.1858 | 0.1765 | 0.1449 | 0.1957 | 0.0853 | 0.1425 | 0.0427 | 0.1367 | 0.0213 | 0.1828 | 0.0002 | 0.0002 | 0.0004 | 0.0000 | 0.0021 | 0.0010 | 0.0084 | 0.0088 | 0.0392 | 0.0312 | 0.0742 | 0.0636 | 0.0517 | 0.0429 | 0.0751 | 0.0700 | 0.7487 | 0.7823 | 0.0007 | 0.0000 | 0.0005 | 0.0016 | 0.0047 | 0.0066 | 0.0145 | 0.0172 | 0.0499 | 0.0620 | 0.0929 | 0.1039 | 0.0689 | 0.0823 | 0.0990 | 0.1175 | 0.6690 | 0.6089 | 0.0010 | 0.0008 | 0.0017 | 0.0109 | 0.0468 | 0.0801 | 0.0606 | 0.0887 | 0.7093 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1246 | 203 | | 5974 | 10831 | 309.6 | 60.88 | 229.94 | 346.15 | 229 | 256 | 278 | 295 | 310 | 324 | 340 | 361 | 389 | 0.0792 | 858 | 0.570 | 89.36 | 14.42 | 1 | 0.0336 | 201 | 0.0010 | 42.49 | 7.110 | 0.1903 | 99557.1 | 33100000 | 11400000000 | 4030000000000 | 0.4350 | 0.2143 | 0.0005 | 0.0000 | 0.0005 | 0.0003 | 0.0049 | 0.0003 | 0.0155 | 0.0019 | 0.0608 | 0.0167 | 0.1043 | 0.0263 | 0.1316 | 0.0288 | 0.1592 | 0.0436 | 0.5228 | 0.8820 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0010 | 0.0003 | 0.0058 | 0.0014 | 0.0243 | 0.0127 | 0.0467 | 0.0199 | 0.0505 | 0.0136 | 0.0664 | 0.0216 | 0.8047 | 0.9302 | 0.0043 | 0.0274 | 0.0228 | 0.0479 | 0.0390 | 0.0548 | 0.1029 | 0.1644 | 0.1484 | 0.1986 | 0.1582 | 0.1712 | 0.1387 | 0.1164 | 0.1278 | 0.1370 | 0.2579 | 0.0822 | 0.0007 | 0.0027 | 0.0050 | 0.0219 | 0.0757 | 0.1286 | 0.1173 | 0.1591 | 0.4890 | 4 | 7 | 9 | 12 | 19 | 103 | 267 | 475 | 758 | 0.0830 | 58.23 | 4.859 | 0.4659 | 172683.0 | 171000000 | 200000000000 | 267000000000000 | 0.3514 | 0.2613 | 0.0254 | 0.0000 | 0.1404 | 0.0131 | 0.2860 | 0.0672 | 0.2014 | 0.1345 | 0.1726 | 0.1921 | 0.0660 | 0.2192 | 0.0609 | 0.1432 | 0.0220 | 0.1188 | 0.0254 | 0.1118 | 0.0000 | 0.0000 | 0.0003 | 0.0010 | 0.0008 | 0.0010 | 0.0074 | 0.0049 | 0.0296 | 0.0227 | 0.0565 | 0.0462 | 0.0486 | 0.0366 | 0.0600 | 0.0545 | 0.7969 | 0.8332 | 0.0003 | 0.0000 | 0.0003 | 0.0017 | 0.0022 | 0.0034 | 0.0078 | 0.0112 | 0.0441 | 0.0454 | 0.0789 | 0.0919 | 0.0582 | 0.0671 | 0.0851 | 0.0824 | 0.7230 | 0.6969 | 0.0006 | 0.0009 | 0.0017 | 0.0086 | 0.0356 | 0.0710 | 0.0529 | 0.0690 | 0.7597 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 396 | 817 | | 4083 | 6204 | 171.9 | 49.75 | 200.16 | 197.44 | 116 | 132 | 144 | 155 | 165 | 176 | 190 | 208 | 235 | 0.1065 | 661 | 1.221 | 103.16 | 41.87 | 1 | 0.0649 | 265 | 0.0012 | 45.98 | 6.996 | 0.1927 | 32023.5 | 6460000 | 1410000000 | 334000000000 | 0.4304 | 0.2154 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0147 | 0.0000 | 0.0334 | 0.0020 | 0.1068 | 0.0322 | 0.2065 | 0.0772 | 0.1709 | 0.0735 | 0.1794 | 0.0958 | 0.2875 | 0.7193 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0068 | 0.0013 | 0.0444 | 0.0205 | 0.0995 | 0.0407 | 0.0762 | 0.0329 | 0.1105 | 0.0477 | 0.6614 | 0.8570 | 0.0036 | 0.0000 | 0.0072 | 0.0256 | 0.0191 | 0.0484 | 0.0656 | 0.0769 | 0.1514 | 0.1852 | 0.1907 | 0.2080 | 0.1085 | 0.1026 | 0.1347 | 0.1453 | 0.3194 | 0.2080 | 0.0006 | 0.0055 | 0.0094 | 0.0303 | 0.1069 | 0.1416 | 0.1085 | 0.1344 | 0.4628 | 19 | 36 | 62 | 91 | 131 | 181 | 248 | 345 | 503 | 0.0039 | 114.79 | 6.970 | 0.2743 | 79040.1 | 42000000 | 26100000000 | 18000000000000 | 0.5116 | 0.1429 | 0.0379 | 0.0018 | 0.1569 | 0.0147 | 0.2288 | 0.0728 | 0.2157 | 0.1053 | 0.1542 | 0.1818 | 0.1085 | 0.2240 | 0.0549 | 0.1567 | 0.0275 | 0.1206 | 0.0157 | 0.1224 | 0.0011 | 0.0003 | 0.0022 | 0.0025 | 0.0037 | 0.0040 | 0.0145 | 0.0126 | 0.0764 | 0.0596 | 0.1135 | 0.1007 | 0.0827 | 0.0795 | 0.1228 | 0.1057 | 0.5829 | 0.6351 | 0.0010 | 0.0006 | 0.0031 | 0.0006 | 0.0078 | 0.0049 | 0.0259 | 0.0401 | 0.0953 | 0.1048 | 0.1472 | 0.1572 | 0.0969 | 0.1030 | 0.1358 | 0.1393 | 0.4870 | 0.4494 | 0.0004 | 0.0035 | 0.0031 | 0.0189 | 0.0817 | 0.1339 | 0.0935 | 0.1299 | 0.5351 |