High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 837 | 568 | | 3810 | 7691 | 452.3 | 131.47 | 221.21 | 376.57 | 230 | 356 | 426 | 457 | 480 | 503 | 528 | 553 | 586 | 0.0787 | 605 | 1.031 | 95.27 | 22.00 | 2 | 0.0559 | 213 | 0.0026 | 14.07 | 6.352 | 0.2995 | 221894.0 | 114000000 | 60800000000 | 33200000000000 | 0.3620 | 0.2645 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0029 | 0.0000 | 0.0119 | 0.0016 | 0.0530 | 0.0188 | 0.0759 | 0.0350 | 0.0740 | 0.0220 | 0.1050 | 0.0373 | 0.6765 | 0.8854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0145 | 0.0142 | 0.0290 | 0.0275 | 0.0145 | 0.0133 | 0.0244 | 0.0245 | 0.9162 | 0.9198 | 0.0021 | 0.0000 | 0.0054 | 0.0122 | 0.0171 | 0.0000 | 0.0289 | 0.0427 | 0.0567 | 0.1037 | 0.0739 | 0.0732 | 0.1017 | 0.1220 | 0.1210 | 0.0793 | 0.5931 | 0.5671 | 0.0004 | 0.0017 | 0.0021 | 0.0084 | 0.0261 | 0.0433 | 0.0517 | 0.0685 | 0.7977 | 9 | 14 | 18 | 23 | 32 | 56 | 165 | 387 | 734 | 0.0801 | 36.23 | 4.662 | 0.5714 | 190720.0 | 231000000 | 326000000000 | 505000000000000 | 0.5310 | 0.1283 | 0.0284 | 0.0000 | 0.2074 | 0.0058 | 0.3466 | 0.0902 | 0.1307 | 0.1645 | 0.1392 | 0.2082 | 0.0881 | 0.2475 | 0.0256 | 0.1092 | 0.0227 | 0.0975 | 0.0114 | 0.0771 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0008 | 0.0089 | 0.0041 | 0.0491 | 0.0454 | 0.0930 | 0.0827 | 0.0637 | 0.0458 | 0.0885 | 0.0827 | 0.6963 | 0.7387 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0052 | 0.0017 | 0.0063 | 0.0112 | 0.0645 | 0.0730 | 0.1096 | 0.1162 | 0.0739 | 0.0691 | 0.1070 | 0.1072 | 0.6329 | 0.6199 | 0.0000 | 0.0005 | 0.0029 | 0.0082 | 0.0629 | 0.0936 | 0.0739 | 0.0975 | 0.6606 | ||
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 445 | 860 | | 2608 | 8307 | 566.5 | 225.38 | 39.43 | 65.37 | 258 | 310 | 392 | 503 | 596 | 677 | 750 | 806 | 842 | 0.0768 | 638 | 0.880 | 77.20 | 20.00 | 3 | 0.0740 | 193 | 0.0009 | 51.94 | 7.257 | 0.1702 | 371659.0 | 266000000 | 199000000000 | 154000000000000 | 0.3620 | 0.2536 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0062 | 0.0029 | 0.0123 | 0.0065 | 0.1200 | 0.0632 | 0.2369 | 0.1142 | 0.1323 | 0.0639 | 0.1477 | 0.1128 | 0.3446 | 0.6358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0012 | 0.0010 | 0.0244 | 0.0282 | 0.0463 | 0.0423 | 0.0220 | 0.0216 | 0.0404 | 0.0423 | 0.8657 | 0.8636 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0010 | 0.0034 | 0.0077 | 0.0151 | 0.0349 | 0.0689 | 0.0668 | 0.1109 | 0.0445 | 0.0723 | 0.0649 | 0.1008 | 0.7803 | 0.6269 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0351 | 0.0537 | 0.0387 | 0.0530 | 0.8173 | 7 | 8 | 10 | 12 | 14 | 19 | 25 | 43 | 117 | 0.0947 | 6.43 | 3.634 | 0.6797 | 5827.2 | 1490000 | 484000000 | 182000000000 | 0.3887 | 0.2572 | 0.0457 | 0.0156 | 0.1087 | 0.0288 | 0.1130 | 0.0600 | 0.1478 | 0.1019 | 0.1870 | 0.1397 | 0.1565 | 0.1265 | 0.1326 | 0.1167 | 0.0913 | 0.1553 | 0.0174 | 0.2555 | 0.0059 | 0.0065 | 0.0054 | 0.0126 | 0.0049 | 0.0153 | 0.0178 | 0.0252 | 0.0425 | 0.0520 | 0.0623 | 0.0566 | 0.0440 | 0.0539 | 0.0667 | 0.0768 | 0.7505 | 0.7012 | 0.0019 | 0.0007 | 0.0051 | 0.0021 | 0.0064 | 0.0064 | 0.0230 | 0.0207 | 0.0499 | 0.0486 | 0.0671 | 0.0671 | 0.0486 | 0.0471 | 0.0633 | 0.0643 | 0.7347 | 0.7429 | 0.0011 | 0.0011 | 0.0034 | 0.0190 | 0.0514 | 0.0587 | 0.0509 | 0.0799 | 0.7345 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 584 | 956 | | 603 | 2463 | 406.2 | 49.35 | 106.45 | 171.74 | 341 | 360 | 374 | 391 | 405 | 421 | 434 | 449 | 475 | 0.1397 | 344 | 0.741 | 102.83 | 29.41 | 1 | 0.4809 | 290 | 0.0035 | 18.91 | 5.793 | 0.2498 | 167409.0 | 70000000 | 29700000000 | 12800000000000 | 0.3625 | 0.2807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0037 | 0.0017 | 0.0608 | 0.0415 | 0.0958 | 0.0630 | 0.0608 | 0.0315 | 0.1105 | 0.0481 | 0.6648 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0034 | 0.0017 | 0.0444 | 0.0415 | 0.0650 | 0.0630 | 0.0342 | 0.0315 | 0.0581 | 0.0481 | 0.7932 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0952 | 0.0000 | 0.1190 | 0.0000 | 0.1905 | 0.0000 | 0.2381 | 0.0000 | 0.1429 | 0.0000 | 0.1190 | 0.0000 | 0.0952 | 0.0000 | 0.0000 | 0.0000 | 0.0101 | 0.0269 | 0.0842 | 0.1010 | 0.1010 | 0.1279 | 0.5488 | 8 | 10 | 11 | 13 | 15 | 30 | 107 | 188 | 310 | 0.1805 | 23.87 | 3.814 | 0.6487 | 40814.5 | 22400000 | 14400000000 | 10100000000000 | 0.5211 | 0.1245 | 0.0866 | 0.0122 | 0.0551 | 0.0528 | 0.1417 | 0.1098 | 0.2205 | 0.1138 | 0.1575 | 0.1301 | 0.1890 | 0.1707 | 0.0787 | 0.1220 | 0.0236 | 0.1260 | 0.0472 | 0.1626 | 0.0012 | 0.0000 | 0.0000 | 0.0047 | 0.0025 | 0.0070 | 0.0149 | 0.0117 | 0.0532 | 0.0493 | 0.0916 | 0.0880 | 0.0668 | 0.0563 | 0.0693 | 0.0599 | 0.7005 | 0.7230 | 0.0015 | 0.0017 | 0.0000 | 0.0033 | 0.0132 | 0.0132 | 0.0264 | 0.0281 | 0.0543 | 0.0677 | 0.1189 | 0.1254 | 0.0764 | 0.0858 | 0.0837 | 0.1073 | 0.6256 | 0.5677 | 0.0000 | 0.0013 | 0.0040 | 0.0148 | 0.0617 | 0.1074 | 0.0671 | 0.0832 | 0.6604 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 438 | 881 | | 789 | 8063 | 74.1 | 31.85 | 47.97 | 131.71 | 30 | 40 | 55 | 65 | 73 | 81 | 92 | 101 | 116 | 0.0633 | 510 | 0.386 | 127.58 | 22.47 | 2 | 0.5982 | 472 | 0.0024 | 38.72 | 6.180 | 0.1858 | 6504.0 | 641928 | 68900000 | 7880000000 | 0.3632 | 0.2507 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0538 | 0.0043 | 0.1000 | 0.0172 | 0.2115 | 0.0948 | 0.1808 | 0.1401 | 0.1846 | 0.1185 | 0.1692 | 0.1789 | 0.0962 | 0.4461 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0135 | 0.0049 | 0.0558 | 0.0395 | 0.0673 | 0.0543 | 0.0635 | 0.0329 | 0.0885 | 0.0625 | 0.7115 | 0.8059 | 0.0000 | 0.0000 | 0.0154 | 0.0139 | 0.0077 | 0.0625 | 0.0346 | 0.0694 | 0.0962 | 0.1319 | 0.1269 | 0.1667 | 0.1038 | 0.1528 | 0.1692 | 0.1250 | 0.4462 | 0.2778 | 0.0026 | 0.0000 | 0.0026 | 0.0179 | 0.0742 | 0.0818 | 0.1023 | 0.1560 | 0.5627 | 11 | 13 | 15 | 16 | 18 | 20 | 22 | 26 | 61 | 0.4823 | 4.88 | 1.769 | 0.8585 | 19647.5 | 17700000 | 20000000000 | 25500000000000 | 0.6771 | 0.1020 | 0.0533 | 0.0311 | 0.1557 | 0.0251 | 0.2172 | 0.0621 | 0.2377 | 0.0932 | 0.2008 | 0.1657 | 0.0820 | 0.2027 | 0.0287 | 0.1686 | 0.0164 | 0.1198 | 0.0082 | 0.1317 | 0.0000 | 0.0147 | 0.0009 | 0.0077 | 0.0046 | 0.0105 | 0.0352 | 0.0252 | 0.0897 | 0.0617 | 0.1175 | 0.0870 | 0.1027 | 0.1024 | 0.1036 | 0.1080 | 0.5458 | 0.5827 | 0.0012 | 0.0013 | 0.0036 | 0.0027 | 0.0060 | 0.0080 | 0.0239 | 0.0213 | 0.1004 | 0.1120 | 0.1470 | 0.1600 | 0.1016 | 0.0973 | 0.1147 | 0.1307 | 0.5018 | 0.4667 | 0.0000 | 0.0011 | 0.0074 | 0.0253 | 0.1077 | 0.1267 | 0.0940 | 0.1109 | 0.5269 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 602 | 376 | | 1156 | 4064 | 474.2 | 143.37 | 10.35 | 8.30 | 315 | 334 | 360 | 391 | 431 | 490 | 562 | 644 | 697 | 0.0947 | 385 | 1.114 | 51.86 | 18.44 | 1 | 0.1211 | 140 | 0.0033 | 11.41 | 6.019 | 0.2906 | 245360.0 | 137000000 | 81700000000 | 51000000000000 | 0.3632 | 0.2648 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0025 | 0.0010 | 0.0327 | 0.0031 | 0.0955 | 0.0462 | 0.1382 | 0.0776 | 0.1709 | 0.0525 | 0.1608 | 0.0860 | 0.3995 | 0.7324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0009 | 0.0136 | 0.0017 | 0.0339 | 0.0304 | 0.0434 | 0.0470 | 0.0542 | 0.0261 | 0.0488 | 0.0487 | 0.8049 | 0.8452 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0118 | 0.0152 | 0.0559 | 0.0812 | 0.0588 | 0.0812 | 0.0559 | 0.0558 | 0.0765 | 0.1269 | 0.7412 | 0.6396 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0412 | 0.0741 | 0.0329 | 0.0658 | 0.7819 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 15 | 0.0098 | 16.68 | 5.103 | 0.3379 | 176.1 | 6409.85 | 409709 | 33400000 | 0.4040 | 0.2136 | 0.0440 | 0.0038 | 0.1040 | 0.0105 | 0.1253 | 0.0332 | 0.2015 | 0.0514 | 0.2154 | 0.0867 | 0.1685 | 0.1160 | 0.1026 | 0.1499 | 0.0330 | 0.2376 | 0.0059 | 0.3110 | 0.0174 | 0.0014 | 0.0349 | 0.0052 | 0.0418 | 0.0193 | 0.0499 | 0.0293 | 0.0774 | 0.0503 | 0.1078 | 0.0748 | 0.1139 | 0.0871 | 0.1390 | 0.1550 | 0.4179 | 0.5775 | 0.0490 | 0.0472 | 0.0672 | 0.0407 | 0.0608 | 0.0650 | 0.0572 | 0.0911 | 0.0762 | 0.1382 | 0.1016 | 0.1154 | 0.1143 | 0.1073 | 0.1661 | 0.1268 | 0.3076 | 0.2683 | 0.0357 | 0.0421 | 0.0562 | 0.0761 | 0.0860 | 0.1094 | 0.1018 | 0.1281 | 0.3645 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 838 | 827 | | 348 | 3785 | 69.6 | 9.59 | 7.19 | 2.56 | 58 | 61 | 63 | 66 | 69 | 71 | 74 | 78 | 83 | 0.1007 | 381 | 1.208 | 26.48 | 9.85 | 4 | 0.2011 | 70 | 0.0757 | 0.82 | 2.819 | 0.6940 | 4931.9 | 356260 | 26200000 | 1970000000 | 0.3634 | 0.2597 | 0.0033 | 0.0000 | 0.0100 | 0.0000 | 0.0133 | 0.0029 | 0.0332 | 0.0144 | 0.0698 | 0.0720 | 0.0997 | 0.0778 | 0.1096 | 0.0692 | 0.2359 | 0.1268 | 0.4252 | 0.6369 | 0.0030 | 0.0000 | 0.0000 | 0.0000 | 0.0090 | 0.0029 | 0.0181 | 0.0144 | 0.0633 | 0.0690 | 0.0843 | 0.0776 | 0.0663 | 0.0690 | 0.1506 | 0.1149 | 0.6054 | 0.6523 | 0.0323 | 1.0000 | 0.0000 | 0.0000 | 0.1613 | 0.0000 | 0.2258 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.1935 | 0.0000 | 0.1290 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0062 | 0.0247 | 0.0988 | 0.1358 | 0.1420 | 0.1235 | 0.1728 | 0.2840 | 4 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 0.0188 | 7.92 | 4.396 | 0.3583 | 58.2 | 526.12 | 5258.33 | 57582.2 | 0.4841 | 0.1761 | 0.0222 | 0.0039 | 0.0672 | 0.0054 | 0.1627 | 0.0219 | 0.2267 | 0.0409 | 0.2391 | 0.0828 | 0.1725 | 0.1441 | 0.0826 | 0.2539 | 0.0246 | 0.3015 | 0.0025 | 0.1456 | 0.0046 | 0.0003 | 0.0185 | 0.0006 | 0.0490 | 0.0059 | 0.0817 | 0.0178 | 0.1214 | 0.0422 | 0.1762 | 0.0716 | 0.1689 | 0.1446 | 0.1823 | 0.2904 | 0.1974 | 0.4267 | 0.1226 | 0.1623 | 0.1493 | 0.1451 | 0.1143 | 0.1019 | 0.1184 | 0.1036 | 0.0917 | 0.0829 | 0.0937 | 0.0760 | 0.0814 | 0.0864 | 0.0937 | 0.1330 | 0.1349 | 0.1088 | 0.0153 | 0.0463 | 0.0769 | 0.1084 | 0.1441 | 0.1724 | 0.1585 | 0.1298 | 0.1483 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 927 | 522 | | 3614 | 6289 | 297.5 | 144.28 | 59.44 | 77.60 | 127 | 157 | 192 | 233 | 266 | 305 | 406 | 465 | 511 | 0.1040 | 654 | 1.229 | 109.25 | 47.52 | 2 | 0.0819 | 296 | 0.0028 | 6.07 | 6.131 | 0.4083 | 109347.0 | 45800000 | 20700000000 | 9820000000000 | 0.3640 | 0.2549 | 0.0012 | 0.0000 | 0.0012 | 0.0006 | 0.0036 | 0.0025 | 0.0324 | 0.0086 | 0.1032 | 0.0531 | 0.1429 | 0.0834 | 0.1273 | 0.0562 | 0.1020 | 0.0828 | 0.4862 | 0.7128 | 0.0005 | 0.0000 | 0.0005 | 0.0004 | 0.0005 | 0.0015 | 0.0076 | 0.0030 | 0.0219 | 0.0203 | 0.0343 | 0.0263 | 0.0281 | 0.0192 | 0.0357 | 0.0312 | 0.8710 | 0.8980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0039 | 0.0331 | 0.0347 | 0.0410 | 0.0597 | 0.0316 | 0.0414 | 0.0458 | 0.0462 | 0.8469 | 0.8141 | 0.0020 | 0.0013 | 0.0027 | 0.0054 | 0.0229 | 0.0404 | 0.0242 | 0.0310 | 0.8700 | 8 | 11 | 14 | 19 | 26 | 38 | 58 | 92 | 162 | 0.0962 | 2.42 | 3.459 | 0.6933 | 9553.8 | 2410000 | 755000000 | 271000000000 | 0.5400 | 0.1318 | 0.0018 | 0.0033 | 0.0126 | 0.0122 | 0.0650 | 0.0236 | 0.1733 | 0.0447 | 0.2365 | 0.0943 | 0.2166 | 0.1561 | 0.1480 | 0.1423 | 0.1137 | 0.1740 | 0.0325 | 0.3496 | 0.0000 | 0.0015 | 0.0005 | 0.0034 | 0.0032 | 0.0076 | 0.0142 | 0.0125 | 0.0500 | 0.0386 | 0.0866 | 0.0773 | 0.0596 | 0.0583 | 0.0830 | 0.0735 | 0.7030 | 0.7273 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0037 | 0.0064 | 0.0197 | 0.0227 | 0.0614 | 0.0716 | 0.1020 | 0.1106 | 0.0694 | 0.0738 | 0.0860 | 0.0865 | 0.6566 | 0.6270 | 0.0011 | 0.0027 | 0.0043 | 0.0160 | 0.0543 | 0.1005 | 0.0660 | 0.0787 | 0.6766 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1068 | 588 | | 752 | 8804 | 837.7 | 183.87 | 21.91 | 27.10 | 548 | 654 | 750 | 824 | 893 | 932 | 956 | 997 | 1042 | 0.0601 | 529 | 0.815 | 73.00 | 17.00 | 2 | 0.2420 | 182 | 0.0018 | 141.74 | 6.411 | 0.1068 | 735551.0 | 669000000 | 625000000000 | 596000000000000 | 0.3650 | 0.2575 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0029 | 0.0667 | 0.0345 | 0.1644 | 0.0576 | 0.1111 | 0.0273 | 0.1333 | 0.0604 | 0.5156 | 0.8173 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0029 | 0.0341 | 0.0345 | 0.0631 | 0.0575 | 0.0341 | 0.0273 | 0.0546 | 0.0489 | 0.8089 | 0.8290 | 0.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0147 | 0.0000 | 0.0662 | 0.0000 | 0.1103 | 0.0000 | 0.2132 | 0.0000 | 0.0882 | 0.0000 | 0.1324 | 0.0000 | 0.3750 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0068 | 0.0430 | 0.0724 | 0.0385 | 0.0747 | 0.7647 | 6 | 7 | 9 | 10 | 12 | 15 | 20 | 29 | 49 | 0.1218 | 2.34 | 3.113 | 0.7219 | 1214.4 | 130232 | 20200000 | 4000000000 | 0.4480 | 0.1854 | 0.0474 | 0.0344 | 0.0720 | 0.0374 | 0.1147 | 0.0502 | 0.1735 | 0.0709 | 0.1782 | 0.1115 | 0.1640 | 0.1388 | 0.1393 | 0.1286 | 0.0891 | 0.1916 | 0.0218 | 0.2366 | 0.0077 | 0.0179 | 0.0123 | 0.0163 | 0.0143 | 0.0191 | 0.0299 | 0.0253 | 0.0486 | 0.0447 | 0.0615 | 0.0613 | 0.0745 | 0.0513 | 0.0968 | 0.0970 | 0.6544 | 0.6671 | 0.0067 | 0.0030 | 0.0062 | 0.0085 | 0.0154 | 0.0164 | 0.0308 | 0.0413 | 0.0677 | 0.0735 | 0.0800 | 0.0874 | 0.0830 | 0.0923 | 0.1148 | 0.1148 | 0.5956 | 0.5628 | 0.0045 | 0.0081 | 0.0134 | 0.0292 | 0.0564 | 0.0714 | 0.0673 | 0.1039 | 0.6458 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 340 | 406 | | 471 | 6514 | 857.4 | 228.67 | 9.61 | 2.99 | 549 | 627 | 690 | 770 | 842 | 920 | 1002 | 1103 | 1189 | 0.0711 | 463 | 1.310 | 25.32 | 10.63 | 1 | 0.1423 | 67 | 0.0025 | 78.35 | 6.025 | 0.1012 | 787377.0 | 767000000 | 784000000000 | 832000000000000 | 0.3659 | 0.2545 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0099 | 0.0024 | 0.1034 | 0.0622 | 0.2512 | 0.0909 | 0.1281 | 0.0646 | 0.1823 | 0.0933 | 0.3251 | 0.6866 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0022 | 0.0515 | 0.0500 | 0.0879 | 0.0609 | 0.0424 | 0.0391 | 0.0515 | 0.0543 | 0.7606 | 0.7935 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0476 | 0.0787 | 0.1667 | 0.1496 | 0.1667 | 0.0315 | 0.0952 | 0.1260 | 0.1667 | 0.6063 | 0.3571 | 0.0000 | 0.0000 | 0.0000 | 0.0089 | 0.0536 | 0.1161 | 0.0402 | 0.0714 | 0.7098 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 12 | 13 | 0.0120 | 10.83 | 4.800 | 0.3191 | 101.2 | 1165.12 | 14657.4 | 201923 | 0.4760 | 0.1625 | 0.0062 | 0.0009 | 0.0309 | 0.0025 | 0.0752 | 0.0063 | 0.1498 | 0.0201 | 0.2096 | 0.0366 | 0.2372 | 0.0807 | 0.1938 | 0.1532 | 0.0783 | 0.3133 | 0.0190 | 0.3862 | 0.0016 | 0.0000 | 0.0096 | 0.0007 | 0.0200 | 0.0031 | 0.0446 | 0.0111 | 0.0824 | 0.0214 | 0.1177 | 0.0415 | 0.1815 | 0.0663 | 0.2235 | 0.1853 | 0.3192 | 0.6707 | 0.1143 | 0.2295 | 0.1414 | 0.1525 | 0.1455 | 0.1311 | 0.1299 | 0.0803 | 0.1225 | 0.0738 | 0.1049 | 0.0754 | 0.0683 | 0.0623 | 0.0751 | 0.1049 | 0.0981 | 0.0902 | 0.0313 | 0.0568 | 0.1064 | 0.1471 | 0.1279 | 0.1328 | 0.1432 | 0.1233 | 0.1312 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 419 | 941 | | 1482 | 6727 | 623.1 | 187.74 | 39.98 | 47.19 | 345 | 427 | 507 | 585 | 646 | 704 | 748 | 798 | 856 | 0.0824 | 554 | 1.155 | 59.68 | 15.62 | 2 | 0.0857 | 127 | 0.0011 | 48.66 | 6.906 | 0.1667 | 423486.0 | 307000000 | 233000000000 | 182000000000000 | 0.3666 | 0.2504 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0009 | 0.0083 | 0.0077 | 0.0998 | 0.0404 | 0.1647 | 0.0482 | 0.1148 | 0.0490 | 0.1664 | 0.0782 | 0.4393 | 0.7756 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0023 | 0.0344 | 0.0313 | 0.0411 | 0.0313 | 0.0306 | 0.0305 | 0.0525 | 0.0477 | 0.8395 | 0.8569 | 0.0022 | 0.0172 | 0.0022 | 0.0000 | 0.0067 | 0.0517 | 0.0247 | 0.0345 | 0.0605 | 0.0862 | 0.0919 | 0.0862 | 0.0740 | 0.0948 | 0.0830 | 0.1207 | 0.6547 | 0.5086 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0375 | 0.0463 | 0.0438 | 0.0688 | 0.7938 | 9 | 12 | 15 | 18 | 23 | 29 | 37 | 55 | 98 | 0.0440 | 4.34 | 4.026 | 0.6372 | 3825.0 | 658362 | 157000000 | 45400000000 | 0.4438 | 0.2100 | 0.0158 | 0.0125 | 0.0565 | 0.0171 | 0.0949 | 0.0260 | 0.1616 | 0.0473 | 0.2011 | 0.0816 | 0.1638 | 0.1247 | 0.1333 | 0.1418 | 0.1209 | 0.1829 | 0.0520 | 0.3662 | 0.0041 | 0.0068 | 0.0127 | 0.0101 | 0.0151 | 0.0120 | 0.0262 | 0.0184 | 0.0454 | 0.0369 | 0.0654 | 0.0513 | 0.0634 | 0.0553 | 0.1079 | 0.0980 | 0.6599 | 0.7113 | 0.0019 | 0.0030 | 0.0038 | 0.0030 | 0.0122 | 0.0098 | 0.0275 | 0.0255 | 0.0487 | 0.0579 | 0.0890 | 0.0826 | 0.0602 | 0.0594 | 0.0922 | 0.0962 | 0.6643 | 0.6627 | 0.0053 | 0.0075 | 0.0150 | 0.0241 | 0.0470 | 0.0780 | 0.0625 | 0.0941 | 0.6665 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 772 | 323 | | 794 | 7091 | 484.4 | 65.35 | 36.00 | 48.85 | 404 | 424 | 442 | 460 | 481 | 495 | 518 | 543 | 578 | 0.0636 | 451 | 0.996 | 53.60 | 13.89 | 2 | 0.1612 | 128 | 0.0034 | 13.68 | 5.871 | 0.2779 | 238955.0 | 120000000 | 61300000000 | 31900000000000 | 0.3670 | 0.2688 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0132 | 0.0038 | 0.0471 | 0.0315 | 0.0838 | 0.0693 | 0.0632 | 0.0290 | 0.0897 | 0.0453 | 0.7015 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0038 | 0.0330 | 0.0315 | 0.0607 | 0.0693 | 0.0356 | 0.0290 | 0.0567 | 0.0453 | 0.8047 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0385 | 0.0000 | 0.0513 | 0.0000 | 0.0897 | 0.0000 | 0.1538 | 0.0000 | 0.0769 | 0.0000 | 0.1795 | 0.0000 | 0.4103 | 0.0000 | 0.0000 | 0.0000 | 0.0105 | 0.0210 | 0.0525 | 0.0787 | 0.0709 | 0.0787 | 0.6877 | 8 | 10 | 12 | 15 | 19 | 24 | 32 | 46 | 83 | 0.0654 | 8.26 | 3.794 | 0.6602 | 3682.1 | 710852 | 183000000 | 55400000000 | 0.4200 | 0.2030 | 0.0272 | 0.0084 | 0.0680 | 0.0199 | 0.1088 | 0.0383 | 0.1519 | 0.0577 | 0.1927 | 0.1013 | 0.1621 | 0.1448 | 0.1361 | 0.1401 | 0.0964 | 0.1758 | 0.0567 | 0.3137 | 0.0038 | 0.0044 | 0.0071 | 0.0076 | 0.0134 | 0.0126 | 0.0217 | 0.0199 | 0.0459 | 0.0354 | 0.0584 | 0.0527 | 0.0764 | 0.0594 | 0.0889 | 0.0916 | 0.6845 | 0.7164 | 0.0013 | 0.0032 | 0.0066 | 0.0056 | 0.0119 | 0.0071 | 0.0291 | 0.0333 | 0.0984 | 0.0881 | 0.0905 | 0.1079 | 0.0707 | 0.1000 | 0.1288 | 0.1087 | 0.5627 | 0.5460 | 0.0011 | 0.0069 | 0.0058 | 0.0185 | 0.0627 | 0.0801 | 0.0764 | 0.1091 | 0.6394 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 77 | 299 | | 362 | 804 | 84.7 | 13.26 | 9.06 | 3.12 | 65 | 72 | 78 | 84 | 87 | 90 | 93 | 96 | 100 | 0.2786 | 224 | 0.728 | 31.40 | 8.49 | 1 | 0.2459 | 89 | 0.0508 | 1.25 | 3.272 | 0.6191 | 7352.5 | 651714 | 58800000 | 5400000000 | 0.3674 | 0.2592 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0351 | 0.0028 | 0.0596 | 0.0442 | 0.1053 | 0.0912 | 0.1368 | 0.0276 | 0.1825 | 0.0608 | 0.4737 | 0.7735 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0000 | 0.0256 | 0.0028 | 0.0415 | 0.0442 | 0.0607 | 0.0912 | 0.0607 | 0.0276 | 0.0799 | 0.0608 | 0.7252 | 0.7735 | 0.0714 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.1429 | 0.0000 | 0.2143 | 0.0000 | 0.1786 | 0.0000 | 0.0357 | 0.0000 | 0.1071 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0242 | 0.0338 | 0.0725 | 0.0725 | 0.0966 | 0.1401 | 0.5556 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 0.0140 | 20.20 | 4.617 | 0.2555 | 91.8 | 1010.84 | 11937.1 | 150060 | 0.5369 | 0.1144 | 0.0442 | 0.0017 | 0.1633 | 0.0034 | 0.2449 | 0.0458 | 0.2415 | 0.1171 | 0.1565 | 0.1460 | 0.0884 | 0.2530 | 0.0476 | 0.2054 | 0.0102 | 0.1562 | 0.0034 | 0.0713 | 0.0018 | 0.0000 | 0.0235 | 0.0000 | 0.0470 | 0.0056 | 0.1302 | 0.0405 | 0.2061 | 0.1103 | 0.2188 | 0.1494 | 0.2116 | 0.1955 | 0.1157 | 0.2598 | 0.0452 | 0.2388 | 0.1042 | 0.3150 | 0.2008 | 0.3858 | 0.2124 | 0.2283 | 0.2432 | 0.0394 | 0.1236 | 0.0315 | 0.0811 | 0.0000 | 0.0270 | 0.0000 | 0.0077 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0424 | 0.1038 | 0.2076 | 0.2182 | 0.1801 | 0.1547 | 0.0657 | 0.0233 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 564 | 431 | | 338 | 1164 | 102.2 | 15.22 | 7.58 | 3.30 | 84 | 88 | 92 | 95 | 102 | 108 | 112 | 115 | 121 | 0.2259 | 263 | 0.523 | 92.70 | 19.72 | 2 | 0.8195 | 277 | 0.0741 | 0.65 | 2.916 | 0.7228 | 10676.7 | 1140000 | 124000000 | 13800000000 | 0.3677 | 0.2665 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0035 | 0.0000 | 0.0070 | 0.0090 | 0.0662 | 0.0448 | 0.1533 | 0.0985 | 0.0732 | 0.0507 | 0.1150 | 0.0836 | 0.5784 | 0.7134 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0063 | 0.0089 | 0.0508 | 0.0444 | 0.1111 | 0.0947 | 0.0381 | 0.0385 | 0.0730 | 0.0621 | 0.7175 | 0.7515 | 0.0000 | 0.0000 | 0.0357 | 0.0000 | 0.0357 | 1.0000 | 0.1071 | 0.0000 | 0.1786 | 0.0000 | 0.1786 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.2143 | 0.0000 | 0.0059 | 0.0000 | 0.0000 | 0.0296 | 0.0710 | 0.0888 | 0.0888 | 0.0947 | 0.6213 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1160 | 0.40 | 1.049 | 0.4095 | 68.4 | 808.275 | 13870.1 | 338018 | 0.5218 | 0.1263 | 0.0138 | 0.0000 | 0.1041 | 0.0030 | 0.2004 | 0.0099 | 0.2338 | 0.0338 | 0.1847 | 0.0746 | 0.1493 | 0.1014 | 0.0727 | 0.1690 | 0.0393 | 0.3052 | 0.0020 | 0.3032 | 0.0071 | 0.0000 | 0.0454 | 0.0000 | 0.0894 | 0.0055 | 0.1504 | 0.0193 | 0.1660 | 0.0654 | 0.1943 | 0.1096 | 0.1191 | 0.1436 | 0.1121 | 0.2818 | 0.1163 | 0.3748 | 0.2041 | 0.0875 | 0.1735 | 0.1250 | 0.0561 | 0.1250 | 0.0765 | 0.0500 | 0.1173 | 0.0625 | 0.1276 | 0.1750 | 0.0918 | 0.1625 | 0.0918 | 0.1000 | 0.0612 | 0.1125 | 0.0463 | 0.1305 | 0.1347 | 0.1705 | 0.1347 | 0.1200 | 0.0968 | 0.0758 | 0.0905 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 797 | 276 | | 3081 | 14857 | 257.1 | 73.60 | 95.99 | 124.19 | 175 | 187 | 202 | 218 | 241 | 266 | 296 | 325 | 367 | 0.0703 | 1045 | 0.709 | 60.54 | 16.03 | 2 | 0.0568 | 175 | 0.0097 | 3.01 | 5.047 | 0.5308 | 71538.3 | 21500000 | 6880000000 | 2330000000000 | 0.3683 | 0.2682 | 0.0023 | 0.0000 | 0.0053 | 0.0000 | 0.0107 | 0.0015 | 0.0328 | 0.0041 | 0.0710 | 0.0354 | 0.1154 | 0.0479 | 0.1054 | 0.0420 | 0.1398 | 0.0593 | 0.5172 | 0.8099 | 0.0014 | 0.0000 | 0.0019 | 0.0000 | 0.0043 | 0.0007 | 0.0125 | 0.0013 | 0.0288 | 0.0202 | 0.0389 | 0.0276 | 0.0408 | 0.0189 | 0.0504 | 0.0315 | 0.8209 | 0.8998 | 0.0013 | 0.0000 | 0.0000 | 0.0111 | 0.0090 | 0.0028 | 0.0168 | 0.0306 | 0.0530 | 0.0889 | 0.0917 | 0.1306 | 0.0646 | 0.1139 | 0.0904 | 0.1500 | 0.6731 | 0.4722 | 0.0015 | 0.0015 | 0.0052 | 0.0126 | 0.0238 | 0.0535 | 0.0416 | 0.0558 | 0.8045 | 12 | 19 | 29 | 42 | 54 | 70 | 95 | 135 | 230 | 0.0663 | 4.54 | 3.869 | 0.7237 | 24635.6 | 11400000 | 7270000000 | 5520000000000 | 0.4425 | 0.1810 | 0.0092 | 0.0039 | 0.0252 | 0.0102 | 0.0406 | 0.0158 | 0.0729 | 0.0304 | 0.1237 | 0.0621 | 0.1566 | 0.0900 | 0.1494 | 0.0954 | 0.1869 | 0.1280 | 0.2356 | 0.5641 | 0.0025 | 0.0017 | 0.0033 | 0.0049 | 0.0040 | 0.0052 | 0.0113 | 0.0100 | 0.0302 | 0.0240 | 0.0458 | 0.0344 | 0.0473 | 0.0408 | 0.0691 | 0.0611 | 0.7864 | 0.8179 | 0.0008 | 0.0007 | 0.0034 | 0.0027 | 0.0059 | 0.0050 | 0.0163 | 0.0174 | 0.0487 | 0.0557 | 0.0704 | 0.0795 | 0.0637 | 0.0651 | 0.0789 | 0.0849 | 0.7118 | 0.6890 | 0.0011 | 0.0052 | 0.0059 | 0.0142 | 0.0363 | 0.0542 | 0.0582 | 0.0716 | 0.7533 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 187 | 499 | | 5159 | 11813 | 530.2 | 150.73 | 46.53 | 99.31 | 336 | 405 | 473 | 515 | 555 | 600 | 635 | 664 | 696 | 0.0781 | 923 | 1.105 | 73.82 | 25.55 | 4 | 0.0382 | 197 | 0.0006 | 44.92 | 7.570 | 0.1925 | 303806.0 | 182000000 | 112000000000 | 70800000000000 | 0.3690 | 0.2568 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0069 | 0.0004 | 0.0167 | 0.0024 | 0.0587 | 0.0163 | 0.0953 | 0.0308 | 0.0843 | 0.0238 | 0.1059 | 0.0400 | 0.6273 | 0.8863 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0025 | 0.0021 | 0.0185 | 0.0146 | 0.0285 | 0.0275 | 0.0217 | 0.0173 | 0.0307 | 0.0266 | 0.8966 | 0.9119 | 0.0019 | 0.0635 | 0.0052 | 0.0476 | 0.0110 | 0.1270 | 0.0213 | 0.1429 | 0.0549 | 0.0635 | 0.0614 | 0.1270 | 0.0627 | 0.0952 | 0.1008 | 0.1270 | 0.6807 | 0.2063 | 0.0010 | 0.0024 | 0.0038 | 0.0076 | 0.0244 | 0.0344 | 0.0337 | 0.0485 | 0.8443 | 6 | 8 | 9 | 10 | 11 | 13 | 17 | 52 | 137 | 0.1781 | 7.69 | 3.150 | 0.7073 | 12026.7 | 6360000 | 4770000000 | 4300000000000 | 0.4827 | 0.1912 | 0.0208 | 0.0043 | 0.0655 | 0.0157 | 0.1042 | 0.0386 | 0.1548 | 0.0815 | 0.1935 | 0.1302 | 0.1905 | 0.1774 | 0.1488 | 0.1245 | 0.0893 | 0.1660 | 0.0327 | 0.2618 | 0.0004 | 0.0007 | 0.0004 | 0.0018 | 0.0011 | 0.0036 | 0.0042 | 0.0075 | 0.0229 | 0.0220 | 0.0362 | 0.0341 | 0.0320 | 0.0242 | 0.0526 | 0.0512 | 0.8502 | 0.8550 | 0.0000 | 0.0000 | 0.0022 | 0.0019 | 0.0044 | 0.0033 | 0.0079 | 0.0071 | 0.0271 | 0.0288 | 0.0411 | 0.0506 | 0.0389 | 0.0378 | 0.0599 | 0.0624 | 0.8186 | 0.8080 | 0.0000 | 0.0012 | 0.0032 | 0.0085 | 0.0263 | 0.0388 | 0.0324 | 0.0599 | 0.8297 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 287 | 523 | | 301 | 5124 | 89.9 | 7.90 | 7.40 | 2.14 | 79 | 82 | 86 | 88 | 90 | 93 | 95 | 97 | 100 | 0.0720 | 369 | 0.946 | 37.36 | 10.77 | 0 | 0.3223 | 97 | 0.1482 | 0.45 | 2.153 | 0.7860 | 8141.3 | 742840 | 68300000 | 6310000000 | 0.3690 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0120 | 0.0120 | 0.0542 | 0.0482 | 0.0783 | 0.1205 | 0.1084 | 0.5663 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1708 | 0.51 | 1.021 | 0.4581 | 59.3 | 508.117 | 4604.6 | 43888.8 | 0.4666 | 0.2005 | 0.0058 | 0.0003 | 0.0341 | 0.0016 | 0.0942 | 0.0123 | 0.1790 | 0.0503 | 0.2344 | 0.1168 | 0.2308 | 0.1953 | 0.1477 | 0.2794 | 0.0651 | 0.2535 | 0.0090 | 0.0906 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0070 | 0.0015 | 0.0224 | 0.0088 | 0.0627 | 0.0354 | 0.1193 | 0.0626 | 0.1833 | 0.1375 | 0.3291 | 0.3390 | 0.2756 | 0.4152 | 0.0900 | 0.2589 | 0.1985 | 0.3018 | 0.2363 | 0.2417 | 0.2038 | 0.1227 | 0.1456 | 0.0577 | 0.0887 | 0.0135 | 0.0278 | 0.0025 | 0.0093 | 0.0012 | 0.0000 | 0.0000 | 0.0003 | 0.0097 | 0.0436 | 0.0951 | 0.1730 | 0.2360 | 0.2304 | 0.1642 | 0.0477 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 814 | | 2851 | 8407 | 391.9 | 153.08 | 40.60 | 64.74 | 211 | 237 | 264 | 302 | 359 | 440 | 510 | 564 | 609 | 0.0793 | 667 | 0.638 | 88.07 | 16.49 | 5 | 0.0831 | 237 | 0.0014 | 33.60 | 6.853 | 0.2650 | 176986.0 | 88700000 | 47600000000 | 26700000000000 | 0.3694 | 0.2467 | 0.0017 | 0.0000 | 0.0000 | 0.0018 | 0.0198 | 0.0037 | 0.0594 | 0.0117 | 0.2228 | 0.0608 | 0.2475 | 0.1148 | 0.1320 | 0.0853 | 0.1254 | 0.1160 | 0.1914 | 0.6059 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0061 | 0.0056 | 0.0386 | 0.0265 | 0.0570 | 0.0521 | 0.0404 | 0.0348 | 0.0545 | 0.0465 | 0.8009 | 0.8341 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0019 | 0.0059 | 0.0049 | 0.0208 | 0.0507 | 0.0639 | 0.0789 | 0.0906 | 0.0478 | 0.0743 | 0.0741 | 0.1055 | 0.7417 | 0.6360 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0430 | 0.0675 | 0.0453 | 0.0606 | 0.7782 | 8 | 10 | 11 | 13 | 15 | 18 | 24 | 42 | 117 | 0.0814 | 2.85 | 3.639 | 0.6573 | 5839.4 | 1330000 | 353000000 | 100000000000 | 0.5410 | 0.1261 | 0.0144 | 0.0101 | 0.0804 | 0.0340 | 0.1835 | 0.0451 | 0.1773 | 0.0975 | 0.1567 | 0.1408 | 0.1649 | 0.1638 | 0.1113 | 0.1408 | 0.0804 | 0.1435 | 0.0309 | 0.2245 | 0.0015 | 0.0040 | 0.0060 | 0.0136 | 0.0144 | 0.0100 | 0.0194 | 0.0244 | 0.0557 | 0.0505 | 0.0815 | 0.0765 | 0.0532 | 0.0589 | 0.0820 | 0.0885 | 0.6864 | 0.6735 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0033 | 0.0050 | 0.0196 | 0.0177 | 0.0629 | 0.0703 | 0.0812 | 0.0809 | 0.0583 | 0.0596 | 0.0799 | 0.0852 | 0.6935 | 0.6806 | 0.0034 | 0.0040 | 0.0017 | 0.0166 | 0.0625 | 0.0763 | 0.0539 | 0.0878 | 0.6936 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 395 | 909 | | 589 | 5786 | 12.0 | 2.37 | 6.24 | 2.23 | 9 | 10 | 11 | 11 | 12 | 12 | 13 | 14 | 15 | 0.0990 | 573 | 0.731 | 73.43 | 17.00 | 0 | 0.3192 | 188 | 0.0185 | 6.32 | 4.289 | 0.3960 | 150.6 | 1953.66 | 26252.6 | 364792 | 0.3695 | 0.2656 | 0.0046 | 0.0000 | 0.0069 | 0.0018 | 0.0324 | 0.0036 | 0.0694 | 0.0164 | 0.1019 | 0.0455 | 0.1343 | 0.0764 | 0.1898 | 0.1218 | 0.1736 | 0.1818 | 0.2870 | 0.5527 | 0.0000 | 0.0000 | 0.0077 | 0.0000 | 0.0174 | 0.0017 | 0.0367 | 0.0156 | 0.0405 | 0.0363 | 0.0656 | 0.0554 | 0.1158 | 0.0606 | 0.1409 | 0.1125 | 0.5753 | 0.7180 | 0.0581 | 0.2857 | 0.0930 | 0.2500 | 0.1860 | 0.1071 | 0.1163 | 0.1786 | 0.1744 | 0.1071 | 0.1163 | 0.0714 | 0.0814 | 0.0000 | 0.1163 | 0.0000 | 0.0581 | 0.0000 | 0.0153 | 0.0337 | 0.0706 | 0.0982 | 0.1135 | 0.1350 | 0.1380 | 0.1503 | 0.2454 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0198 | 11.10 | 4.314 | 0.3248 | 43.9 | 336.777 | 2778.03 | 24382.5 | 0.5530 | 0.1191 | 0.0068 | 0.0000 | 0.0407 | 0.0041 | 0.1143 | 0.0182 | 0.2166 | 0.0597 | 0.2673 | 0.1261 | 0.2088 | 0.2311 | 0.1023 | 0.2725 | 0.0370 | 0.2133 | 0.0062 | 0.0750 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0121 | 0.0032 | 0.0364 | 0.0132 | 0.0907 | 0.0355 | 0.1684 | 0.0778 | 0.2678 | 0.1906 | 0.2778 | 0.3647 | 0.1454 | 0.3144 | 0.1144 | 0.2816 | 0.2397 | 0.3609 | 0.2950 | 0.2346 | 0.1896 | 0.0927 | 0.1073 | 0.0268 | 0.0392 | 0.0034 | 0.0141 | 0.0000 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0090 | 0.0356 | 0.0844 | 0.1569 | 0.2511 | 0.2490 | 0.1644 | 0.0477 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 995 | 342 | | 564 | 6866 | 365.6 | 120.17 | 7.19 | 3.22 | 232 | 252 | 275 | 304 | 342 | 374 | 420 | 483 | 545 | 0.0756 | 519 | 0.945 | 118.23 | 29.12 | 4 | 0.5071 | 286 | 0.0058 | 7.76 | 5.422 | 0.3429 | 148105.0 | 65900000 | 31700000000 | 16200000000000 | 0.3696 | 0.2532 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0194 | 0.0133 | 0.1311 | 0.0421 | 0.2136 | 0.1242 | 0.1505 | 0.0643 | 0.1553 | 0.0931 | 0.3301 | 0.6630 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0056 | 0.0500 | 0.0297 | 0.0667 | 0.0816 | 0.0444 | 0.0260 | 0.0639 | 0.0464 | 0.7667 | 0.8108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0114 | 0.0195 | 0.0341 | 0.0779 | 0.0909 | 0.0974 | 0.1250 | 0.0649 | 0.0568 | 0.0779 | 0.1591 | 0.6623 | 0.5227 | 0.0000 | 0.0000 | 0.0000 | 0.0082 | 0.0617 | 0.0864 | 0.0453 | 0.0864 | 0.7119 | 4 | 4 | 5 | 6 | 7 | 7 | 8 | 10 | 12 | 0.0970 | 0.30 | 0.907 | 0.3778 | 62.0 | 621.741 | 7050.74 | 88336.7 | 0.5310 | 0.1386 | 0.0333 | 0.0083 | 0.0940 | 0.0274 | 0.1573 | 0.0625 | 0.2031 | 0.1170 | 0.2115 | 0.1983 | 0.1705 | 0.2399 | 0.0918 | 0.2042 | 0.0329 | 0.1141 | 0.0055 | 0.0284 | 0.0071 | 0.0004 | 0.0280 | 0.0051 | 0.0552 | 0.0227 | 0.0722 | 0.0545 | 0.0905 | 0.0935 | 0.1106 | 0.1358 | 0.1192 | 0.1525 | 0.1513 | 0.1718 | 0.3659 | 0.3639 | 0.0766 | 0.0859 | 0.0697 | 0.0791 | 0.0676 | 0.0846 | 0.0855 | 0.0784 | 0.0907 | 0.0914 | 0.1096 | 0.1153 | 0.1311 | 0.1535 | 0.1809 | 0.1869 | 0.1883 | 0.1248 | 0.0208 | 0.0594 | 0.0898 | 0.1063 | 0.1084 | 0.1039 | 0.0962 | 0.1215 | 0.2938 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 550 | 347 | | 2625 | 7570 | 364.6 | 100.61 | 57.27 | 93.59 | 229 | 271 | 313 | 338 | 359 | 381 | 405 | 462 | 513 | 0.0856 | 648 | 0.595 | 111.40 | 19.31 | 7 | 0.1051 | 276 | 0.0012 | 33.64 | 6.958 | 0.2138 | 143052.0 | 59700000 | 26200000000 | 12000000000000 | 0.3697 | 0.2506 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0023 | 0.0162 | 0.0079 | 0.0855 | 0.0410 | 0.1179 | 0.0843 | 0.0929 | 0.0531 | 0.0899 | 0.0754 | 0.5969 | 0.7346 | 0.0000 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0016 | 0.0333 | 0.0276 | 0.0455 | 0.0470 | 0.0414 | 0.0272 | 0.0510 | 0.0404 | 0.8253 | 0.8549 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0216 | 0.0225 | 0.0396 | 0.0722 | 0.1367 | 0.1075 | 0.2086 | 0.0690 | 0.1223 | 0.1043 | 0.1295 | 0.6244 | 0.3309 | 0.0000 | 0.0008 | 0.0048 | 0.0191 | 0.0590 | 0.0901 | 0.0726 | 0.0989 | 0.6547 | 8 | 10 | 12 | 14 | 18 | 23 | 38 | 87 | 161 | 0.1461 | 5.86 | 3.394 | 0.7357 | 12038.0 | 4300000 | 1950000000 | 1010000000000 | 0.6794 | 0.0692 | 0.0238 | 0.0092 | 0.0506 | 0.0184 | 0.1131 | 0.0407 | 0.1310 | 0.0512 | 0.2292 | 0.1168 | 0.2083 | 0.1444 | 0.1280 | 0.1470 | 0.0893 | 0.1745 | 0.0268 | 0.2979 | 0.0019 | 0.0025 | 0.0014 | 0.0038 | 0.0068 | 0.0059 | 0.0106 | 0.0106 | 0.0323 | 0.0317 | 0.0651 | 0.0571 | 0.0458 | 0.0440 | 0.0719 | 0.0693 | 0.7641 | 0.7751 | 0.0006 | 0.0000 | 0.0012 | 0.0006 | 0.0035 | 0.0075 | 0.0098 | 0.0106 | 0.0368 | 0.0399 | 0.0725 | 0.0761 | 0.0478 | 0.0586 | 0.0725 | 0.0773 | 0.7553 | 0.7294 | 0.0005 | 0.0011 | 0.0053 | 0.0090 | 0.0329 | 0.0638 | 0.0515 | 0.0733 | 0.7625 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 742 | 248 | | 1325 | 5484 | 955.8 | 428.77 | 8.01 | 2.97 | 481 | 526 | 610 | 705 | 833 | 1020 | 1224 | 1418 | 1627 | 0.0857 | 470 | 0.902 | 36.72 | 12.08 | 1 | 0.0823 | 109 | 0.0016 | 81.60 | 6.699 | 0.1744 | 1100000.0 | 1440000000 | 2060000000000 | 3.12E+15 | 0.3703 | 0.2538 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0110 | 0.0015 | 0.1801 | 0.0682 | 0.2904 | 0.1091 | 0.1360 | 0.0636 | 0.1324 | 0.1197 | 0.2500 | 0.6348 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0360 | 0.0308 | 0.0596 | 0.0473 | 0.0263 | 0.0226 | 0.0526 | 0.0473 | 0.8241 | 0.8520 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0022 | 0.0128 | 0.0511 | 0.0511 | 0.0644 | 0.0831 | 0.0378 | 0.0511 | 0.0578 | 0.0895 | 0.7867 | 0.7093 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0417 | 0.0609 | 0.0330 | 0.0557 | 0.8070 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 12 | 0.0134 | 9.32 | 4.700 | 0.3378 | 73.0 | 745.296 | 8414.3 | 103808 | 0.4557 | 0.1834 | 0.0246 | 0.0007 | 0.0780 | 0.0051 | 0.1560 | 0.0156 | 0.2275 | 0.0356 | 0.2236 | 0.0749 | 0.1629 | 0.1318 | 0.0948 | 0.2083 | 0.0289 | 0.2962 | 0.0039 | 0.2318 | 0.0045 | 0.0000 | 0.0206 | 0.0000 | 0.0448 | 0.0044 | 0.0775 | 0.0143 | 0.1104 | 0.0457 | 0.1205 | 0.0733 | 0.1415 | 0.1199 | 0.1700 | 0.2262 | 0.3102 | 0.5161 | 0.0910 | 0.1312 | 0.0842 | 0.1131 | 0.0910 | 0.1508 | 0.1045 | 0.1146 | 0.1270 | 0.1071 | 0.1222 | 0.1056 | 0.1283 | 0.1071 | 0.1236 | 0.0920 | 0.1283 | 0.0784 | 0.0246 | 0.0667 | 0.0896 | 0.1051 | 0.0958 | 0.1127 | 0.1221 | 0.1629 | 0.2206 |