High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 735 | 634 | | 3383 | 13602 | 420.5 | 93.73 | 24.16 | 65.07 | 310 | 345 | 369 | 393 | 413 | 435 | 458 | 483 | 531 | 0.0471 | 641 | 0.708 | 187.75 | 42.58 | 1 | 0.1469 | 497 | 0.0008 | 81.64 | 7.362 | 0.1445 | 185607.0 | 86200000 | 42200000000 | 21900000000000 | 0.4414 | 0.2109 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0190 | 0.0000 | 0.0557 | 0.0201 | 0.1348 | 0.0447 | 0.1232 | 0.0352 | 0.1517 | 0.0569 | 0.5108 | 0.8430 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0000 | 0.0327 | 0.0138 | 0.0779 | 0.0312 | 0.0610 | 0.0204 | 0.0832 | 0.0309 | 0.7391 | 0.9038 | 0.0169 | 0.0000 | 0.0127 | 0.0252 | 0.0465 | 0.0377 | 0.0465 | 0.0755 | 0.1269 | 0.1447 | 0.1882 | 0.1698 | 0.0867 | 0.1195 | 0.1501 | 0.1069 | 0.3256 | 0.3208 | 0.0000 | 0.0050 | 0.0126 | 0.0320 | 0.0961 | 0.1420 | 0.1030 | 0.1470 | 0.4623 | 5 | 6 | 7 | 7 | 9 | 10 | 13 | 19 | 43 | 0.1856 | 1.96 | 2.069 | 0.6343 | 4817.1 | 2540000 | 1750000000 | 1330000000000 | 0.5397 | 0.1164 | 0.0580 | 0.0279 | 0.1116 | 0.0343 | 0.1949 | 0.0594 | 0.2024 | 0.1054 | 0.1741 | 0.1577 | 0.1310 | 0.1758 | 0.0759 | 0.1589 | 0.0387 | 0.1368 | 0.0134 | 0.1438 | 0.0052 | 0.0139 | 0.0041 | 0.0154 | 0.0067 | 0.0198 | 0.0191 | 0.0302 | 0.0479 | 0.0395 | 0.0621 | 0.0552 | 0.0592 | 0.0599 | 0.0943 | 0.0738 | 0.7012 | 0.6922 | 0.0010 | 0.0012 | 0.0035 | 0.0035 | 0.0045 | 0.0104 | 0.0205 | 0.0267 | 0.0730 | 0.0818 | 0.0985 | 0.1021 | 0.0725 | 0.0754 | 0.1151 | 0.1155 | 0.6113 | 0.5833 | 0.0026 | 0.0039 | 0.0039 | 0.0176 | 0.0511 | 0.0815 | 0.0686 | 0.1047 | 0.6662 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 977 | 301 | | 13922 | 26863 | 211.1 | 59.41 | 243.85 | 302.54 | 140 | 161 | 177 | 191 | 205 | 221 | 237 | 258 | 290 | 0.0529 | 1421 | 0.517 | 152.46 | 33.12 | 3 | 0.0332 | 462 | 0.0010 | 40.05 | 7.158 | 0.1901 | 48082.9 | 11800000 | 3080000000 | 860000000000 | 0.4554 | 0.1927 | 0.0003 | 0.0000 | 0.0020 | 0.0002 | 0.0126 | 0.0010 | 0.0382 | 0.0033 | 0.1052 | 0.0256 | 0.1779 | 0.0652 | 0.1708 | 0.0702 | 0.1853 | 0.1080 | 0.3078 | 0.7265 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0019 | 0.0001 | 0.0091 | 0.0017 | 0.0405 | 0.0146 | 0.0746 | 0.0338 | 0.0714 | 0.0312 | 0.0998 | 0.0497 | 0.7024 | 0.8688 | 0.0033 | 0.0099 | 0.0092 | 0.0108 | 0.0191 | 0.0381 | 0.0654 | 0.1094 | 0.1325 | 0.1930 | 0.1822 | 0.1872 | 0.1190 | 0.0969 | 0.1457 | 0.1367 | 0.3236 | 0.2179 | 0.0009 | 0.0022 | 0.0066 | 0.0320 | 0.0904 | 0.1306 | 0.1036 | 0.1336 | 0.5001 | 8 | 10 | 14 | 35 | 97 | 203 | 327 | 486 | 702 | 0.0530 | 47.80 | 5.717 | 0.4211 | 150993.0 | 122000000 | 114000000000 | 121000000000000 | 0.4350 | 0.2316 | 0.0406 | 0.0021 | 0.1879 | 0.0150 | 0.2563 | 0.1084 | 0.1660 | 0.1540 | 0.1487 | 0.1826 | 0.0976 | 0.1847 | 0.0579 | 0.1280 | 0.0269 | 0.1004 | 0.0182 | 0.1248 | 0.0001 | 0.0000 | 0.0006 | 0.0003 | 0.0014 | 0.0012 | 0.0074 | 0.0074 | 0.0475 | 0.0377 | 0.0763 | 0.0659 | 0.0613 | 0.0479 | 0.0889 | 0.0735 | 0.7164 | 0.7660 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0025 | 0.0033 | 0.0148 | 0.0202 | 0.0626 | 0.0746 | 0.1137 | 0.1211 | 0.0770 | 0.0770 | 0.1055 | 0.1172 | 0.6229 | 0.5861 | 0.0001 | 0.0008 | 0.0026 | 0.0105 | 0.0553 | 0.0925 | 0.0698 | 0.1031 | 0.6653 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 933 | 123 | | 15895 | 25256 | 160.6 | 49.99 | 222.36 | 201.78 | 108 | 123 | 135 | 145 | 155 | 167 | 180 | 197 | 224 | 0.0522 | 1319 | 1.013 | 68.60 | 26.63 | 1 | 0.0118 | 188 | 0.0011 | 38.56 | 7.182 | 0.2007 | 28277.2 | 5410000 | 1120000000 | 250000000000 | 0.4469 | 0.2019 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0004 | 0.0316 | 0.0036 | 0.1026 | 0.0245 | 0.1744 | 0.0573 | 0.1683 | 0.0626 | 0.1924 | 0.0950 | 0.3207 | 0.7567 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0020 | 0.0001 | 0.0095 | 0.0013 | 0.0356 | 0.0107 | 0.0680 | 0.0249 | 0.0660 | 0.0239 | 0.0986 | 0.0414 | 0.7192 | 0.8976 | 0.0038 | 0.0039 | 0.0105 | 0.0143 | 0.0212 | 0.0306 | 0.0646 | 0.0971 | 0.1280 | 0.1519 | 0.1664 | 0.1956 | 0.1271 | 0.1167 | 0.1414 | 0.1402 | 0.3371 | 0.2497 | 0.0010 | 0.0033 | 0.0088 | 0.0321 | 0.0763 | 0.1269 | 0.1097 | 0.1304 | 0.5115 | 26 | 46 | 75 | 111 | 161 | 221 | 294 | 379 | 507 | 0.0037 | 85.09 | 7.177 | 0.2606 | 90156.2 | 49000000 | 32300000000 | 24700000000000 | 0.5277 | 0.1518 | 0.0405 | 0.0017 | 0.1859 | 0.0114 | 0.2913 | 0.0812 | 0.1595 | 0.1431 | 0.1289 | 0.2051 | 0.0931 | 0.1986 | 0.0540 | 0.1320 | 0.0300 | 0.1078 | 0.0167 | 0.1190 | 0.0003 | 0.0003 | 0.0017 | 0.0005 | 0.0033 | 0.0024 | 0.0137 | 0.0100 | 0.0734 | 0.0561 | 0.1231 | 0.1010 | 0.0947 | 0.0796 | 0.1369 | 0.1199 | 0.5529 | 0.6302 | 0.0009 | 0.0011 | 0.0033 | 0.0060 | 0.0084 | 0.0108 | 0.0290 | 0.0412 | 0.1013 | 0.1114 | 0.1586 | 0.1680 | 0.1119 | 0.1173 | 0.1427 | 0.1435 | 0.4438 | 0.4007 | 0.0005 | 0.0008 | 0.0048 | 0.0220 | 0.0840 | 0.1483 | 0.1014 | 0.1428 | 0.4955 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 991 | 259 | | 6417 | 8793 | 106.8 | 27.20 | 230.17 | 178.27 | 75 | 83 | 90 | 97 | 103 | 111 | 119 | 129 | 143 | 0.0945 | 831 | 1.049 | 86.61 | 32.57 | 1 | 0.0376 | 241 | 0.0029 | 14.53 | 6.155 | 0.2937 | 12146.3 | 1470000 | 189000000 | 26000000000 | 0.4126 | 0.2368 | 0.0008 | 0.0000 | 0.0025 | 0.0003 | 0.0124 | 0.0009 | 0.0395 | 0.0028 | 0.1013 | 0.0232 | 0.1836 | 0.0560 | 0.1626 | 0.0640 | 0.1775 | 0.0993 | 0.3197 | 0.7534 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0037 | 0.0006 | 0.0134 | 0.0005 | 0.0424 | 0.0139 | 0.0779 | 0.0310 | 0.0647 | 0.0240 | 0.0895 | 0.0392 | 0.7067 | 0.8904 | 0.0023 | 0.0180 | 0.0054 | 0.0315 | 0.0161 | 0.0856 | 0.0889 | 0.1464 | 0.1418 | 0.1937 | 0.1916 | 0.1914 | 0.1448 | 0.0766 | 0.1402 | 0.1126 | 0.2690 | 0.1441 | 0.0020 | 0.0051 | 0.0136 | 0.0322 | 0.0770 | 0.1126 | 0.1079 | 0.1228 | 0.5268 | 22 | 53 | 93 | 153 | 208 | 257 | 312 | 379 | 480 | 0.0024 | 67.01 | 7.297 | 0.2596 | 84755.6 | 38600000 | 20300000000 | 11900000000000 | 0.5009 | 0.1509 | 0.0115 | 0.0013 | 0.0850 | 0.0111 | 0.1797 | 0.0293 | 0.1714 | 0.0723 | 0.2027 | 0.1309 | 0.1675 | 0.1982 | 0.1023 | 0.1576 | 0.0588 | 0.1709 | 0.0211 | 0.2285 | 0.0002 | 0.0000 | 0.0019 | 0.0005 | 0.0042 | 0.0025 | 0.0137 | 0.0090 | 0.0529 | 0.0395 | 0.1047 | 0.0857 | 0.0764 | 0.0623 | 0.1081 | 0.0863 | 0.6379 | 0.7142 | 0.0003 | 0.0016 | 0.0046 | 0.0049 | 0.0083 | 0.0178 | 0.0293 | 0.0348 | 0.0788 | 0.1077 | 0.1569 | 0.1814 | 0.1143 | 0.1174 | 0.1359 | 0.1344 | 0.4716 | 0.4000 | 0.0005 | 0.0023 | 0.0055 | 0.0193 | 0.0660 | 0.1225 | 0.0971 | 0.1207 | 0.5661 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 266 | 832 | | 5052 | 10241 | 147.7 | 42.12 | 164.11 | 146.78 | 101 | 114 | 123 | 132 | 141 | 151 | 163 | 178 | 201 | 0.0842 | 862 | 1.052 | 93.96 | 28.02 | 1 | 0.0449 | 227 | 0.0015 | 34.75 | 6.782 | 0.2136 | 23601.0 | 4100000 | 775000000 | 160000000000 | 0.4351 | 0.2145 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0119 | 0.0004 | 0.0418 | 0.0025 | 0.1162 | 0.0275 | 0.1757 | 0.0555 | 0.1934 | 0.0737 | 0.1916 | 0.1095 | 0.2680 | 0.7309 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0152 | 0.0008 | 0.0452 | 0.0174 | 0.0714 | 0.0304 | 0.0903 | 0.0289 | 0.1092 | 0.0521 | 0.6665 | 0.8702 | 0.0029 | 0.0073 | 0.0164 | 0.0171 | 0.0299 | 0.0465 | 0.0598 | 0.1345 | 0.1583 | 0.1736 | 0.1631 | 0.1760 | 0.1361 | 0.1100 | 0.1544 | 0.1271 | 0.2790 | 0.2078 | 0.0023 | 0.0041 | 0.0120 | 0.0322 | 0.0989 | 0.1427 | 0.1141 | 0.1542 | 0.4395 | 13 | 30 | 59 | 89 | 123 | 168 | 218 | 280 | 374 | 0.0051 | 65.13 | 6.912 | 0.2905 | 48476.3 | 18800000 | 8740000000 | 4630000000000 | 0.4979 | 0.1489 | 0.0225 | 0.0023 | 0.1359 | 0.0100 | 0.2239 | 0.0492 | 0.1838 | 0.0904 | 0.1746 | 0.1755 | 0.1352 | 0.2178 | 0.0803 | 0.1586 | 0.0331 | 0.1509 | 0.0106 | 0.1453 | 0.0000 | 0.0002 | 0.0014 | 0.0012 | 0.0045 | 0.0043 | 0.0163 | 0.0104 | 0.0593 | 0.0502 | 0.0964 | 0.0849 | 0.0821 | 0.0672 | 0.1055 | 0.0971 | 0.6345 | 0.6846 | 0.0014 | 0.0028 | 0.0029 | 0.0077 | 0.0063 | 0.0120 | 0.0284 | 0.0359 | 0.0831 | 0.0921 | 0.1287 | 0.1354 | 0.1006 | 0.1051 | 0.1284 | 0.1343 | 0.5201 | 0.4747 | 0.0002 | 0.0029 | 0.0059 | 0.0176 | 0.0699 | 0.1148 | 0.0813 | 0.1176 | 0.5899 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1226 | 292 | | 1447 | 9024 | 65.1 | 24.28 | 181.44 | 210.82 | 35 | 44 | 51 | 57 | 63 | 69 | 76 | 85 | 96 | 0.0659 | 595 | 0.521 | 83.49 | 16.03 | 5 | 0.1714 | 248 | 0.0021 | 31.10 | 6.361 | 0.2003 | 4823.6 | 400876 | 37000000 | 3760000000 | 0.3867 | 0.2406 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0198 | 0.0028 | 0.0843 | 0.0170 | 0.1802 | 0.0405 | 0.2215 | 0.1008 | 0.1884 | 0.1329 | 0.1818 | 0.1951 | 0.1124 | 0.5108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0016 | 0.0109 | 0.0095 | 0.0465 | 0.0247 | 0.0812 | 0.0366 | 0.0663 | 0.0461 | 0.1238 | 0.0700 | 0.6693 | 0.8115 | 0.0049 | 0.0255 | 0.0099 | 0.0204 | 0.0025 | 0.0510 | 0.0765 | 0.1071 | 0.1284 | 0.1837 | 0.1778 | 0.1735 | 0.1654 | 0.1173 | 0.1407 | 0.1378 | 0.2938 | 0.1837 | 0.0015 | 0.0029 | 0.0059 | 0.0322 | 0.1025 | 0.1259 | 0.1127 | 0.1347 | 0.4817 | 19 | 26 | 41 | 64 | 97 | 142 | 205 | 308 | 477 | 0.0338 | 9.96 | 5.000 | 0.5659 | 77361.5 | 47900000 | 36100000000 | 30600000000000 | 0.5191 | 0.1524 | 0.0220 | 0.0015 | 0.0828 | 0.0094 | 0.1118 | 0.0342 | 0.1577 | 0.0768 | 0.2126 | 0.1412 | 0.1427 | 0.1684 | 0.1228 | 0.1273 | 0.0918 | 0.1446 | 0.0559 | 0.2967 | 0.0006 | 0.0005 | 0.0025 | 0.0012 | 0.0034 | 0.0009 | 0.0104 | 0.0092 | 0.0533 | 0.0431 | 0.0855 | 0.0726 | 0.0676 | 0.0528 | 0.0917 | 0.0820 | 0.6851 | 0.7378 | 0.0008 | 0.0013 | 0.0027 | 0.0022 | 0.0059 | 0.0040 | 0.0164 | 0.0211 | 0.0632 | 0.0723 | 0.1096 | 0.1159 | 0.0780 | 0.0858 | 0.1166 | 0.1204 | 0.6069 | 0.5768 | 0.0003 | 0.0020 | 0.0043 | 0.0143 | 0.0627 | 0.0953 | 0.0720 | 0.1040 | 0.6450 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1060 | 148 | | 9173 | 22344 | 294.9 | 54.87 | 142.27 | 167.42 | 227 | 246 | 262 | 276 | 290 | 304 | 321 | 343 | 371 | 0.0689 | 1540 | 0.872 | 128.71 | 44.38 | 1 | 0.0395 | 362 | 0.0007 | 53.70 | 7.461 | 0.1589 | 89976.7 | 28400000 | 9240000000 | 3100000000000 | 0.4189 | 0.2273 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0039 | 0.0000 | 0.0119 | 0.0010 | 0.0544 | 0.0105 | 0.1011 | 0.0239 | 0.1296 | 0.0218 | 0.1648 | 0.0345 | 0.5330 | 0.9084 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0059 | 0.0002 | 0.0246 | 0.0088 | 0.0420 | 0.0180 | 0.0587 | 0.0104 | 0.0811 | 0.0154 | 0.7860 | 0.9472 | 0.0035 | 0.0359 | 0.0110 | 0.0256 | 0.0311 | 0.0769 | 0.0876 | 0.1487 | 0.1090 | 0.1436 | 0.1739 | 0.1641 | 0.1256 | 0.1128 | 0.1387 | 0.1231 | 0.3195 | 0.1692 | 0.0012 | 0.0047 | 0.0077 | 0.0323 | 0.0798 | 0.1131 | 0.0949 | 0.1254 | 0.5411 | 14 | 17 | 22 | 39 | 72 | 114 | 176 | 260 | 379 | 0.0282 | 29.29 | 5.688 | 0.4480 | 48267.7 | 23800000 | 15100000000 | 12000000000000 | 0.5526 | 0.1273 | 0.0495 | 0.0023 | 0.1676 | 0.0182 | 0.2382 | 0.0872 | 0.1820 | 0.1262 | 0.1201 | 0.1819 | 0.1042 | 0.1777 | 0.0735 | 0.1315 | 0.0360 | 0.1131 | 0.0288 | 0.1618 | 0.0010 | 0.0004 | 0.0013 | 0.0008 | 0.0025 | 0.0027 | 0.0122 | 0.0114 | 0.0574 | 0.0459 | 0.1001 | 0.0810 | 0.0689 | 0.0643 | 0.0971 | 0.0872 | 0.6595 | 0.7063 | 0.0003 | 0.0003 | 0.0007 | 0.0013 | 0.0044 | 0.0053 | 0.0173 | 0.0217 | 0.0820 | 0.0881 | 0.1194 | 0.1360 | 0.0834 | 0.0891 | 0.1164 | 0.1154 | 0.5761 | 0.5428 | 0.0005 | 0.0013 | 0.0029 | 0.0153 | 0.0705 | 0.1085 | 0.0767 | 0.1091 | 0.6152 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1017 | 554 | | 378 | 9755 | 70.8 | 9.18 | 6.27 | 2.35 | 58 | 62 | 65 | 69 | 72 | 74 | 76 | 79 | 82 | 0.0685 | 668 | 1.025 | 80.23 | 26.63 | 2 | 0.5556 | 210 | 0.0307 | 2.20 | 3.799 | 0.5317 | 5100.6 | 373029 | 27700000 | 2080000000 | 0.3766 | 0.2528 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0121 | 0.0053 | 0.0725 | 0.0556 | 0.0816 | 0.0635 | 0.0816 | 0.0503 | 0.1178 | 0.0688 | 0.6284 | 0.7566 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0116 | 0.0053 | 0.0607 | 0.0556 | 0.0665 | 0.0635 | 0.0520 | 0.0503 | 0.0838 | 0.0688 | 0.7197 | 0.7566 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.0000 | 0.0000 | 0.1333 | 0.0000 | 0.0000 | 0.0093 | 0.0139 | 0.0324 | 0.0694 | 0.0787 | 0.0972 | 0.1481 | 0.5509 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.2315 | 0.45 | 1.048 | 0.5873 | 44.8 | 356.698 | 3133.82 | 30121.9 | 0.5230 | 0.1563 | 0.0095 | 0.0016 | 0.0423 | 0.0054 | 0.1159 | 0.0156 | 0.1913 | 0.0399 | 0.2491 | 0.0756 | 0.2068 | 0.1496 | 0.1260 | 0.2580 | 0.0507 | 0.3008 | 0.0085 | 0.1535 | 0.0009 | 0.0000 | 0.0033 | 0.0003 | 0.0157 | 0.0022 | 0.0417 | 0.0102 | 0.0896 | 0.0267 | 0.1561 | 0.0434 | 0.2071 | 0.1072 | 0.2316 | 0.2692 | 0.2540 | 0.5409 | 0.0990 | 0.1881 | 0.1831 | 0.2085 | 0.1795 | 0.1599 | 0.1502 | 0.1178 | 0.1272 | 0.0944 | 0.0980 | 0.0655 | 0.0618 | 0.0505 | 0.0512 | 0.0589 | 0.0501 | 0.0565 | 0.0080 | 0.0313 | 0.0735 | 0.1349 | 0.1725 | 0.1695 | 0.1459 | 0.1396 | 0.1248 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1090 | 760 | | 3567 | 11438 | 100.2 | 24.43 | 44.83 | 30.71 | 75 | 81 | 85 | 89 | 93 | 99 | 107 | 120 | 138 | 0.1156 | 1322 | 1.193 | 93.86 | 31.91 | 1 | 0.0648 | 231 | 0.0052 | 8.86 | 5.685 | 0.3588 | 10638.8 | 1200000 | 144000000 | 18300000000 | 0.5064 | 0.1576 | 0.0023 | 0.0003 | 0.0099 | 0.0003 | 0.0208 | 0.0025 | 0.0406 | 0.0084 | 0.0848 | 0.0491 | 0.1196 | 0.0870 | 0.1255 | 0.0600 | 0.1512 | 0.0901 | 0.4454 | 0.7022 | 0.0017 | 0.0000 | 0.0065 | 0.0000 | 0.0075 | 0.0014 | 0.0222 | 0.0056 | 0.0491 | 0.0352 | 0.0713 | 0.0681 | 0.0699 | 0.0405 | 0.0883 | 0.0602 | 0.6835 | 0.7889 | 0.0070 | 0.0179 | 0.0098 | 0.0208 | 0.0223 | 0.0119 | 0.0377 | 0.0327 | 0.0628 | 0.0744 | 0.0964 | 0.1220 | 0.0712 | 0.0804 | 0.0936 | 0.1042 | 0.5992 | 0.5357 | 0.0042 | 0.0063 | 0.0134 | 0.0324 | 0.0746 | 0.0824 | 0.0866 | 0.1056 | 0.5944 | 11 | 17 | 23 | 31 | 40 | 49 | 58 | 68 | 84 | 0.0159 | 3.14 | 4.641 | 0.5376 | 2952.1 | 252025 | 26700000 | 3450000000 | 0.5531 | 0.1427 | 0.0123 | 0.0087 | 0.0497 | 0.0166 | 0.1286 | 0.0231 | 0.1677 | 0.0522 | 0.1986 | 0.1185 | 0.1774 | 0.1539 | 0.1341 | 0.1548 | 0.0925 | 0.1952 | 0.0390 | 0.2770 | 0.0024 | 0.0039 | 0.0044 | 0.0055 | 0.0071 | 0.0049 | 0.0198 | 0.0124 | 0.0492 | 0.0397 | 0.0746 | 0.0608 | 0.0741 | 0.0533 | 0.1097 | 0.0866 | 0.6586 | 0.7329 | 0.0035 | 0.0089 | 0.0079 | 0.0171 | 0.0208 | 0.0250 | 0.0406 | 0.0545 | 0.0844 | 0.1094 | 0.1267 | 0.1306 | 0.1138 | 0.1248 | 0.1473 | 0.1608 | 0.4550 | 0.3689 | 0.0023 | 0.0047 | 0.0093 | 0.0271 | 0.0662 | 0.0972 | 0.1038 | 0.1410 | 0.5484 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1186 | 399 | | 7576 | 21944 | 290.6 | 51.00 | 184.64 | 218.05 | 227 | 248 | 263 | 275 | 288 | 301 | 316 | 333 | 359 | 0.0463 | 1015 | 1.252 | 130.06 | 51.55 | 1 | 0.0429 | 325 | 0.0008 | 52.05 | 7.382 | 0.1525 | 87051.1 | 26800000 | 8500000000 | 2760000000000 | 0.4494 | 0.2025 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0025 | 0.0000 | 0.0115 | 0.0007 | 0.0438 | 0.0130 | 0.1032 | 0.0258 | 0.1170 | 0.0248 | 0.1591 | 0.0387 | 0.5622 | 0.8970 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0054 | 0.0005 | 0.0213 | 0.0107 | 0.0519 | 0.0209 | 0.0498 | 0.0152 | 0.0734 | 0.0201 | 0.7964 | 0.9326 | 0.0071 | 0.0446 | 0.0162 | 0.0804 | 0.0396 | 0.1339 | 0.0974 | 0.1429 | 0.1511 | 0.1696 | 0.1785 | 0.1964 | 0.1247 | 0.0893 | 0.1400 | 0.0804 | 0.2454 | 0.0625 | 0.0011 | 0.0033 | 0.0096 | 0.0325 | 0.0771 | 0.1263 | 0.1151 | 0.1403 | 0.4947 | 12 | 15 | 19 | 33 | 78 | 152 | 249 | 366 | 521 | 0.0296 | 46.67 | 5.933 | 0.4162 | 81634.4 | 47000000 | 31600000000 | 23900000000000 | 0.4913 | 0.1440 | 0.0391 | 0.0020 | 0.1582 | 0.0154 | 0.2635 | 0.0835 | 0.1628 | 0.1494 | 0.1571 | 0.1988 | 0.1185 | 0.1822 | 0.0575 | 0.1124 | 0.0276 | 0.1077 | 0.0155 | 0.1486 | 0.0003 | 0.0002 | 0.0004 | 0.0007 | 0.0030 | 0.0010 | 0.0080 | 0.0073 | 0.0456 | 0.0397 | 0.0771 | 0.0667 | 0.0544 | 0.0443 | 0.0810 | 0.0710 | 0.7301 | 0.7690 | 0.0004 | 0.0003 | 0.0014 | 0.0011 | 0.0050 | 0.0044 | 0.0109 | 0.0177 | 0.0535 | 0.0620 | 0.1030 | 0.1046 | 0.0676 | 0.0770 | 0.0949 | 0.1153 | 0.6633 | 0.6176 | 0.0005 | 0.0014 | 0.0029 | 0.0115 | 0.0492 | 0.0817 | 0.0614 | 0.0892 | 0.7022 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 623 | 128 | | 5953 | 11599 | 530.3 | 117.08 | 264.39 | 415.53 | 392 | 428 | 458 | 485 | 513 | 546 | 584 | 630 | 696 | 0.0813 | 943 | 0.967 | 130.08 | 35.78 | 1 | 0.0519 | 309 | 0.0004 | 120.83 | 7.914 | 0.1104 | 294936.0 | 172000000 | 105000000000 | 66500000000000 | 0.4302 | 0.2128 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0059 | 0.0004 | 0.0185 | 0.0013 | 0.0765 | 0.0215 | 0.1506 | 0.0396 | 0.1458 | 0.0420 | 0.1956 | 0.0637 | 0.4064 | 0.8314 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0076 | 0.0003 | 0.0384 | 0.0137 | 0.0657 | 0.0215 | 0.0657 | 0.0178 | 0.0966 | 0.0280 | 0.7218 | 0.9187 | 0.0044 | 0.0061 | 0.0000 | 0.0214 | 0.0142 | 0.0428 | 0.0567 | 0.1284 | 0.1258 | 0.1743 | 0.1709 | 0.2110 | 0.1116 | 0.1376 | 0.1515 | 0.1407 | 0.3649 | 0.1376 | 0.0015 | 0.0015 | 0.0083 | 0.0326 | 0.0701 | 0.1227 | 0.0848 | 0.1148 | 0.5638 | 9 | 12 | 15 | 20 | 32 | 87 | 235 | 532 | 918 | 0.0999 | 84.61 | 5.018 | 0.5316 | 242548.0 | 294000000 | 414000000000 | 650000000000000 | 0.4380 | 0.2212 | 0.0713 | 0.0000 | 0.2240 | 0.0143 | 0.2261 | 0.1554 | 0.1344 | 0.1964 | 0.1303 | 0.1954 | 0.0876 | 0.1573 | 0.0448 | 0.0925 | 0.0407 | 0.0944 | 0.0407 | 0.0944 | 0.0006 | 0.0000 | 0.0003 | 0.0013 | 0.0014 | 0.0020 | 0.0089 | 0.0075 | 0.0371 | 0.0362 | 0.0674 | 0.0619 | 0.0438 | 0.0415 | 0.0726 | 0.0714 | 0.7680 | 0.7782 | 0.0006 | 0.0000 | 0.0000 | 0.0007 | 0.0013 | 0.0014 | 0.0055 | 0.0051 | 0.0375 | 0.0471 | 0.0789 | 0.0792 | 0.0465 | 0.0567 | 0.0818 | 0.0857 | 0.7478 | 0.7240 | 0.0003 | 0.0030 | 0.0021 | 0.0087 | 0.0382 | 0.0659 | 0.0454 | 0.0728 | 0.7636 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 359 | 542 | | 4621 | 10762 | 146.2 | 33.43 | 222.69 | 177.49 | 107 | 118 | 125 | 134 | 142 | 151 | 161 | 172 | 191 | 0.0783 | 843 | 0.885 | 76.16 | 18.03 | 1 | 0.0390 | 180 | 0.0019 | 23.24 | 6.525 | 0.2373 | 22484.2 | 3640000 | 620000000 | 111000000000 | 0.4346 | 0.2115 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0058 | 0.0002 | 0.0194 | 0.0023 | 0.0890 | 0.0207 | 0.1549 | 0.0458 | 0.1876 | 0.0490 | 0.2146 | 0.0759 | 0.3279 | 0.8061 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0024 | 0.0002 | 0.0059 | 0.0009 | 0.0386 | 0.0147 | 0.0709 | 0.0249 | 0.0768 | 0.0190 | 0.1183 | 0.0332 | 0.6866 | 0.9071 | 0.0061 | 0.0150 | 0.0207 | 0.0187 | 0.0292 | 0.0487 | 0.0901 | 0.1423 | 0.1681 | 0.1723 | 0.1791 | 0.2247 | 0.1108 | 0.1086 | 0.1462 | 0.1236 | 0.2497 | 0.1461 | 0.0009 | 0.0043 | 0.0080 | 0.0326 | 0.0913 | 0.1456 | 0.1210 | 0.1504 | 0.4459 | 44 | 73 | 105 | 144 | 183 | 226 | 275 | 342 | 445 | 0.0015 | 74.52 | 7.246 | 0.2302 | 81090.3 | 40900000 | 26000000000 | 19500000000000 | 0.4630 | 0.1957 | 0.0142 | 0.0014 | 0.0752 | 0.0062 | 0.1565 | 0.0283 | 0.1896 | 0.0627 | 0.1844 | 0.1479 | 0.1697 | 0.2060 | 0.1092 | 0.1512 | 0.0700 | 0.1579 | 0.0312 | 0.2384 | 0.0009 | 0.0003 | 0.0020 | 0.0012 | 0.0062 | 0.0036 | 0.0222 | 0.0121 | 0.0621 | 0.0464 | 0.1076 | 0.0967 | 0.0994 | 0.0695 | 0.1261 | 0.1058 | 0.5735 | 0.6645 | 0.0015 | 0.0019 | 0.0047 | 0.0070 | 0.0174 | 0.0174 | 0.0375 | 0.0557 | 0.0962 | 0.1161 | 0.1535 | 0.1663 | 0.1125 | 0.1199 | 0.1367 | 0.1389 | 0.4401 | 0.3768 | 0.0007 | 0.0043 | 0.0107 | 0.0285 | 0.0859 | 0.1281 | 0.1071 | 0.1381 | 0.4965 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 418 | 234 | | 17233 | 30716 | 142.7 | 48.74 | 171.07 | 136.88 | 91 | 103 | 113 | 123 | 134 | 146 | 159 | 179 | 208 | 0.0589 | 1808 | 0.875 | 171.23 | 50.54 | 6 | 0.0257 | 443 | 0.0012 | 32.99 | 7.078 | 0.2149 | 22747.1 | 4030000 | 792000000 | 170000000000 | 0.4209 | 0.2369 | 0.0013 | 0.0001 | 0.0039 | 0.0003 | 0.0174 | 0.0014 | 0.0505 | 0.0050 | 0.1309 | 0.0315 | 0.1949 | 0.0683 | 0.1734 | 0.0758 | 0.1834 | 0.1141 | 0.2444 | 0.7035 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0058 | 0.0006 | 0.0141 | 0.0022 | 0.0490 | 0.0156 | 0.0844 | 0.0320 | 0.0765 | 0.0347 | 0.0991 | 0.0569 | 0.6692 | 0.8578 | 0.0040 | 0.0044 | 0.0055 | 0.0098 | 0.0144 | 0.0186 | 0.0431 | 0.0667 | 0.1096 | 0.1382 | 0.1445 | 0.1770 | 0.1086 | 0.1078 | 0.1442 | 0.1436 | 0.4260 | 0.3338 | 0.0011 | 0.0020 | 0.0089 | 0.0326 | 0.0833 | 0.1183 | 0.0961 | 0.1280 | 0.5296 | 21 | 42 | 74 | 109 | 144 | 182 | 223 | 278 | 356 | 0.0059 | 37.42 | 6.647 | 0.3123 | 47999.4 | 17500000 | 7750000000 | 3980000000000 | 0.5887 | 0.1133 | 0.0187 | 0.0011 | 0.0941 | 0.0056 | 0.1941 | 0.0281 | 0.1770 | 0.0790 | 0.1770 | 0.1591 | 0.1489 | 0.1991 | 0.0907 | 0.1550 | 0.0639 | 0.1574 | 0.0358 | 0.2154 | 0.0003 | 0.0001 | 0.0018 | 0.0009 | 0.0044 | 0.0024 | 0.0138 | 0.0084 | 0.0576 | 0.0421 | 0.1092 | 0.0858 | 0.0878 | 0.0696 | 0.1288 | 0.1035 | 0.5963 | 0.6873 | 0.0013 | 0.0017 | 0.0050 | 0.0076 | 0.0119 | 0.0155 | 0.0341 | 0.0397 | 0.0958 | 0.1103 | 0.1473 | 0.1630 | 0.1089 | 0.1127 | 0.1449 | 0.1590 | 0.4508 | 0.3906 | 0.0007 | 0.0032 | 0.0079 | 0.0194 | 0.0783 | 0.1344 | 0.1013 | 0.1353 | 0.5195 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1030 | 874 | | 3673 | 4603 | 174.5 | 51.15 | 215.89 | 185.55 | 121 | 134 | 145 | 155 | 165 | 176 | 189 | 208 | 237 | 0.1288 | 593 | 1.114 | 100.81 | 36.62 | 1 | 0.0719 | 264 | 0.0014 | 45.62 | 6.851 | 0.2136 | 33048.1 | 6890000 | 1610000000 | 426000000000 | 0.4339 | 0.2118 | 0.0005 | 0.0000 | 0.0029 | 0.0003 | 0.0103 | 0.0009 | 0.0275 | 0.0024 | 0.1035 | 0.0323 | 0.1844 | 0.0579 | 0.1540 | 0.0695 | 0.1923 | 0.1040 | 0.3247 | 0.7325 | 0.0004 | 0.0000 | 0.0011 | 0.0003 | 0.0054 | 0.0006 | 0.0098 | 0.0011 | 0.0493 | 0.0198 | 0.0761 | 0.0320 | 0.0692 | 0.0315 | 0.1036 | 0.0546 | 0.6853 | 0.8602 | 0.0042 | 0.0032 | 0.0083 | 0.0288 | 0.0208 | 0.0192 | 0.0554 | 0.1058 | 0.1302 | 0.1827 | 0.1911 | 0.1538 | 0.0817 | 0.1250 | 0.1440 | 0.1410 | 0.3643 | 0.2404 | 0.0033 | 0.0026 | 0.0131 | 0.0328 | 0.0858 | 0.1343 | 0.0878 | 0.1304 | 0.5098 | 21 | 49 | 86 | 127 | 170 | 218 | 276 | 353 | 485 | 0.0039 | 128.55 | 7.024 | 0.2296 | 81028.4 | 39900000 | 23100000000 | 14900000000000 | 0.4728 | 0.1730 | 0.0382 | 0.0006 | 0.1401 | 0.0110 | 0.2051 | 0.0760 | 0.1949 | 0.1098 | 0.1809 | 0.1696 | 0.1121 | 0.1982 | 0.0650 | 0.1404 | 0.0420 | 0.1261 | 0.0217 | 0.1683 | 0.0009 | 0.0004 | 0.0026 | 0.0011 | 0.0035 | 0.0044 | 0.0215 | 0.0139 | 0.0953 | 0.0645 | 0.1156 | 0.1004 | 0.0888 | 0.0751 | 0.1301 | 0.1084 | 0.5417 | 0.6319 | 0.0013 | 0.0042 | 0.0080 | 0.0059 | 0.0195 | 0.0210 | 0.0436 | 0.0470 | 0.1113 | 0.1293 | 0.1482 | 0.1839 | 0.1261 | 0.1167 | 0.1368 | 0.1310 | 0.4051 | 0.3610 | 0.0021 | 0.0016 | 0.0102 | 0.0376 | 0.0950 | 0.1432 | 0.1073 | 0.1266 | 0.4764 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 234 | 799 | | 13982 | 47347 | 267.6 | 72.72 | 111.48 | 151.15 | 180 | 206 | 227 | 244 | 261 | 277 | 298 | 324 | 366 | 0.0290 | 1375 | 0.637 | 134.38 | 29.41 | 4 | 0.0255 | 356 | 0.0013 | 25.91 | 6.963 | 0.2170 | 76872.3 | 23600000 | 7750000000 | 2700000000000 | 0.4326 | 0.2214 | 0.0001 | 0.0000 | 0.0013 | 0.0001 | 0.0055 | 0.0004 | 0.0221 | 0.0029 | 0.0806 | 0.0231 | 0.1501 | 0.0550 | 0.1533 | 0.0526 | 0.1827 | 0.0775 | 0.4043 | 0.7885 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0002 | 0.0076 | 0.0010 | 0.0363 | 0.0137 | 0.0660 | 0.0277 | 0.0623 | 0.0230 | 0.0865 | 0.0394 | 0.7392 | 0.8952 | 0.0052 | 0.0034 | 0.0097 | 0.0101 | 0.0207 | 0.0151 | 0.0446 | 0.0772 | 0.1034 | 0.1394 | 0.1383 | 0.2065 | 0.0906 | 0.0999 | 0.1317 | 0.1360 | 0.4557 | 0.3123 | 0.0005 | 0.0028 | 0.0097 | 0.0328 | 0.0738 | 0.1215 | 0.0977 | 0.1158 | 0.5454 | 7 | 9 | 11 | 16 | 39 | 79 | 133 | 204 | 314 | 0.0819 | 10.81 | 4.504 | 0.5328 | 35272.3 | 16700000 | 10300000000 | 7940000000000 | 0.3283 | 0.3071 | 0.0637 | 0.0018 | 0.1924 | 0.0219 | 0.2593 | 0.1299 | 0.1590 | 0.1336 | 0.1409 | 0.1843 | 0.0919 | 0.1786 | 0.0492 | 0.1220 | 0.0306 | 0.1122 | 0.0130 | 0.1156 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0005 | 0.0071 | 0.0063 | 0.0513 | 0.0394 | 0.0875 | 0.0698 | 0.0707 | 0.0553 | 0.1096 | 0.0865 | 0.6726 | 0.7417 | 0.0003 | 0.0002 | 0.0010 | 0.0011 | 0.0030 | 0.0057 | 0.0155 | 0.0207 | 0.0717 | 0.0816 | 0.1258 | 0.1367 | 0.0873 | 0.0954 | 0.1313 | 0.1337 | 0.5642 | 0.5249 | 0.0001 | 0.0005 | 0.0021 | 0.0105 | 0.0627 | 0.1064 | 0.0809 | 0.1220 | 0.6149 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1018 | 588 | | 3811 | 2194 | 152.8 | 45.25 | 165.29 | 120.38 | 109 | 118 | 126 | 134 | 142 | 151 | 164 | 180 | 214 | 0.2334 | 512 | 1.053 | 95.88 | 21.84 | 1 | 0.0559 | 213 | 0.0019 | 30.81 | 6.595 | 0.2281 | 25408.3 | 4650000 | 946000000 | 214000000000 | 0.3988 | 0.2432 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0266 | 0.0015 | 0.1000 | 0.0318 | 0.1613 | 0.0588 | 0.1678 | 0.0558 | 0.1730 | 0.0780 | 0.3604 | 0.7742 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0145 | 0.0008 | 0.0469 | 0.0184 | 0.0800 | 0.0301 | 0.0793 | 0.0235 | 0.0959 | 0.0379 | 0.6781 | 0.8893 | 0.0014 | 0.0000 | 0.0201 | 0.0000 | 0.0086 | 0.0026 | 0.0459 | 0.0741 | 0.1119 | 0.1481 | 0.1607 | 0.1984 | 0.0947 | 0.1085 | 0.1349 | 0.1614 | 0.4218 | 0.3069 | 0.0040 | 0.0094 | 0.0101 | 0.0330 | 0.0808 | 0.1359 | 0.0969 | 0.1151 | 0.5148 | 45 | 64 | 85 | 108 | 136 | 167 | 200 | 252 | 322 | 0.0021 | 74.42 | 6.577 | 0.2161 | 41805.4 | 14100000 | 5770000000 | 2690000000000 | 0.5152 | 0.1357 | 0.0346 | 0.0000 | 0.1364 | 0.0171 | 0.2165 | 0.0798 | 0.1667 | 0.1277 | 0.1688 | 0.1631 | 0.1190 | 0.1836 | 0.0909 | 0.1072 | 0.0455 | 0.1482 | 0.0216 | 0.1733 | 0.0000 | 0.0000 | 0.0009 | 0.0014 | 0.0097 | 0.0043 | 0.0292 | 0.0264 | 0.1205 | 0.0785 | 0.1763 | 0.1527 | 0.1045 | 0.0935 | 0.1523 | 0.1456 | 0.4066 | 0.4975 | 0.0030 | 0.0057 | 0.0045 | 0.0038 | 0.0285 | 0.0286 | 0.0615 | 0.0782 | 0.1529 | 0.1794 | 0.2144 | 0.2271 | 0.1229 | 0.1355 | 0.1439 | 0.1240 | 0.2684 | 0.2176 | 0.0011 | 0.0034 | 0.0202 | 0.0506 | 0.1406 | 0.1755 | 0.1260 | 0.1586 | 0.3240 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 780 | 834 | | 6318 | 19340 | 609.7 | 114.55 | 120.41 | 134.66 | 470 | 509 | 540 | 570 | 600 | 630 | 663 | 704 | 767 | 0.0498 | 964 | 0.726 | 86.01 | 16.03 | 1 | 0.0298 | 188 | 0.0006 | 70.14 | 7.636 | 0.1483 | 384808.0 | 251000000 | 169000000000 | 118000000000000 | 0.4102 | 0.2380 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0085 | 0.0016 | 0.0475 | 0.0150 | 0.0953 | 0.0289 | 0.1183 | 0.0271 | 0.1343 | 0.0400 | 0.5943 | 0.8873 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0039 | 0.0005 | 0.0245 | 0.0116 | 0.0479 | 0.0198 | 0.0540 | 0.0127 | 0.0670 | 0.0219 | 0.8018 | 0.9335 | 0.0021 | 0.0054 | 0.0053 | 0.0109 | 0.0253 | 0.0489 | 0.0654 | 0.1522 | 0.1139 | 0.2011 | 0.1414 | 0.1902 | 0.0876 | 0.1467 | 0.1382 | 0.1250 | 0.4209 | 0.1196 | 0.0017 | 0.0024 | 0.0051 | 0.0330 | 0.0633 | 0.1113 | 0.1144 | 0.1208 | 0.5480 | 10 | 12 | 16 | 32 | 64 | 109 | 162 | 224 | 319 | 0.0289 | 26.76 | 5.663 | 0.4276 | 32630.8 | 11900000 | 5250000000 | 2670000000000 | 0.4590 | 0.1836 | 0.0336 | 0.0024 | 0.1633 | 0.0091 | 0.2748 | 0.0760 | 0.1537 | 0.1425 | 0.1526 | 0.1964 | 0.1089 | 0.2073 | 0.0699 | 0.1294 | 0.0304 | 0.1211 | 0.0128 | 0.1158 | 0.0004 | 0.0001 | 0.0014 | 0.0003 | 0.0024 | 0.0013 | 0.0079 | 0.0078 | 0.0464 | 0.0377 | 0.0825 | 0.0694 | 0.0683 | 0.0566 | 0.0985 | 0.0850 | 0.6922 | 0.7418 | 0.0002 | 0.0005 | 0.0017 | 0.0016 | 0.0039 | 0.0052 | 0.0136 | 0.0186 | 0.0639 | 0.0748 | 0.1128 | 0.1253 | 0.0862 | 0.0934 | 0.1154 | 0.1298 | 0.6023 | 0.5508 | 0.0001 | 0.0010 | 0.0030 | 0.0108 | 0.0575 | 0.0944 | 0.0796 | 0.1088 | 0.6448 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1086 | 620 | | 4452 | 3745 | 173.1 | 35.31 | 160.12 | 114.34 | 133 | 145 | 153 | 161 | 169 | 177 | 186 | 197 | 216 | 0.1522 | 570 | 1.194 | 77.34 | 28.86 | 1 | 0.0442 | 197 | 0.0021 | 21.97 | 6.469 | 0.2475 | 31225.1 | 5890000 | 1170000000 | 246000000000 | 0.3936 | 0.2497 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0002 | 0.0175 | 0.0012 | 0.0519 | 0.0169 | 0.1051 | 0.0386 | 0.1236 | 0.0286 | 0.1721 | 0.0435 | 0.5232 | 0.8710 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0100 | 0.0009 | 0.0257 | 0.0133 | 0.0524 | 0.0252 | 0.0561 | 0.0137 | 0.0820 | 0.0252 | 0.7704 | 0.9216 | 0.0032 | 0.0056 | 0.0323 | 0.0113 | 0.0258 | 0.0339 | 0.0855 | 0.0734 | 0.1403 | 0.1864 | 0.1645 | 0.2034 | 0.1339 | 0.0847 | 0.1339 | 0.1073 | 0.2806 | 0.2938 | 0.0020 | 0.0039 | 0.0158 | 0.0331 | 0.0805 | 0.1051 | 0.1111 | 0.1362 | 0.5123 | 40 | 68 | 87 | 108 | 131 | 156 | 189 | 244 | 330 | 0.0027 | 39.04 | 6.449 | 0.3029 | 38710.2 | 12200000 | 4630000000 | 1970000000000 | 0.4732 | 0.1655 | 0.0072 | 0.0025 | 0.0929 | 0.0144 | 0.1158 | 0.0439 | 0.1411 | 0.0640 | 0.1496 | 0.1193 | 0.1604 | 0.1532 | 0.1086 | 0.1293 | 0.0989 | 0.1494 | 0.1255 | 0.3239 | 0.0021 | 0.0012 | 0.0031 | 0.0032 | 0.0093 | 0.0057 | 0.0260 | 0.0114 | 0.0639 | 0.0584 | 0.1070 | 0.0852 | 0.0826 | 0.0697 | 0.1158 | 0.1010 | 0.5903 | 0.6642 | 0.0027 | 0.0011 | 0.0046 | 0.0057 | 0.0146 | 0.0137 | 0.0401 | 0.0538 | 0.0866 | 0.0985 | 0.1486 | 0.1546 | 0.0902 | 0.1168 | 0.1395 | 0.1730 | 0.4731 | 0.3826 | 0.0021 | 0.0041 | 0.0110 | 0.0336 | 0.0782 | 0.1221 | 0.0912 | 0.1276 | 0.5302 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 370 | 294 | | 5485 | 10563 | 124.0 | 34.56 | 117.76 | 103.27 | 86 | 95 | 103 | 110 | 117 | 126 | 136 | 150 | 170 | 0.0846 | 894 | 0.963 | 95.52 | 33.42 | 1 | 0.0500 | 274 | 0.0022 | 24.84 | 6.477 | 0.2498 | 16564.2 | 2390000 | 374000000 | 63000000000 | 0.4073 | 0.2446 | 0.0010 | 0.0000 | 0.0044 | 0.0000 | 0.0153 | 0.0012 | 0.0435 | 0.0059 | 0.1084 | 0.0244 | 0.1855 | 0.0590 | 0.1804 | 0.0658 | 0.1696 | 0.1047 | 0.2919 | 0.7390 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0066 | 0.0000 | 0.0172 | 0.0021 | 0.0434 | 0.0153 | 0.0767 | 0.0283 | 0.0797 | 0.0280 | 0.0995 | 0.0527 | 0.6749 | 0.8736 | 0.0026 | 0.0083 | 0.0097 | 0.0145 | 0.0150 | 0.0455 | 0.0607 | 0.1074 | 0.1514 | 0.1653 | 0.1752 | 0.2045 | 0.1294 | 0.1157 | 0.1488 | 0.1322 | 0.3072 | 0.2066 | 0.0026 | 0.0047 | 0.0129 | 0.0331 | 0.0786 | 0.1301 | 0.1108 | 0.1447 | 0.4826 | 16 | 26 | 41 | 63 | 88 | 117 | 152 | 200 | 268 | 0.0059 | 25.56 | 6.335 | 0.3474 | 24530.7 | 6760000 | 2220000000 | 822000000000 | 0.5829 | 0.1325 | 0.0182 | 0.0019 | 0.0846 | 0.0051 | 0.1973 | 0.0296 | 0.1849 | 0.0819 | 0.1784 | 0.1674 | 0.1426 | 0.2027 | 0.0990 | 0.1609 | 0.0736 | 0.1539 | 0.0215 | 0.1966 | 0.0002 | 0.0007 | 0.0018 | 0.0013 | 0.0042 | 0.0037 | 0.0149 | 0.0111 | 0.0556 | 0.0427 | 0.0899 | 0.0705 | 0.0803 | 0.0677 | 0.1118 | 0.0992 | 0.6413 | 0.7031 | 0.0011 | 0.0011 | 0.0040 | 0.0021 | 0.0078 | 0.0088 | 0.0221 | 0.0284 | 0.0709 | 0.0935 | 0.1183 | 0.1285 | 0.1002 | 0.1113 | 0.1330 | 0.1373 | 0.5425 | 0.4891 | 0.0010 | 0.0021 | 0.0040 | 0.0209 | 0.0659 | 0.0949 | 0.0885 | 0.1221 | 0.6005 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 921 | 862 | | 6477 | 15065 | 403.9 | 109.37 | 121.63 | 165.75 | 277 | 309 | 337 | 363 | 389 | 418 | 449 | 490 | 551 | 0.0525 | 791 | 0.968 | 109.17 | 33.06 | 1 | 0.0426 | 276 | 0.0006 | 77.54 | 7.589 | 0.1419 | 175073.0 | 81300000 | 40400000000 | 21300000000000 | 0.4463 | 0.2101 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0155 | 0.0004 | 0.0348 | 0.0028 | 0.1035 | 0.0244 | 0.1860 | 0.0559 | 0.1699 | 0.0627 | 0.1719 | 0.0842 | 0.3162 | 0.7696 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0023 | 0.0002 | 0.0093 | 0.0018 | 0.0399 | 0.0117 | 0.0837 | 0.0302 | 0.0747 | 0.0280 | 0.0983 | 0.0411 | 0.6910 | 0.8871 | 0.0029 | 0.0053 | 0.0174 | 0.0106 | 0.0101 | 0.0301 | 0.0702 | 0.0816 | 0.1259 | 0.1667 | 0.1802 | 0.1613 | 0.0948 | 0.1241 | 0.1324 | 0.1436 | 0.3661 | 0.2766 | 0.0003 | 0.0010 | 0.0055 | 0.0331 | 0.0776 | 0.1479 | 0.1117 | 0.1317 | 0.4912 | 7 | 9 | 13 | 25 | 47 | 84 | 137 | 215 | 339 | 0.0659 | 15.12 | 4.966 | 0.5541 | 42265.8 | 22000000 | 14400000000 | 10800000000000 | 0.3883 | 0.2650 | 0.0173 | 0.0015 | 0.0965 | 0.0090 | 0.2033 | 0.0324 | 0.1790 | 0.0799 | 0.1931 | 0.1735 | 0.1468 | 0.2123 | 0.0950 | 0.1508 | 0.0502 | 0.1388 | 0.0188 | 0.2017 | 0.0002 | 0.0002 | 0.0013 | 0.0011 | 0.0020 | 0.0012 | 0.0089 | 0.0089 | 0.0379 | 0.0318 | 0.0609 | 0.0533 | 0.0508 | 0.0440 | 0.0713 | 0.0640 | 0.7668 | 0.7956 | 0.0000 | 0.0003 | 0.0007 | 0.0005 | 0.0044 | 0.0032 | 0.0125 | 0.0119 | 0.0504 | 0.0631 | 0.0900 | 0.0998 | 0.0666 | 0.0700 | 0.0928 | 0.1054 | 0.6826 | 0.6458 | 0.0002 | 0.0002 | 0.0026 | 0.0098 | 0.0427 | 0.0786 | 0.0642 | 0.0823 | 0.7195 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 425 | 828 | | 9686 | 14128 | 100.3 | 24.59 | 205.89 | 202.72 | 72 | 79 | 85 | 91 | 97 | 103 | 110 | 120 | 135 | 0.0773 | 1092 | 0.773 | 63.03 | 19.85 | 4 | 0.0184 | 178 | 0.0016 | 27.28 | 6.760 | 0.2225 | 10667.4 | 1200000 | 143000000 | 18000000000 | 0.4311 | 0.2206 | 0.0007 | 0.0000 | 0.0025 | 0.0002 | 0.0089 | 0.0003 | 0.0289 | 0.0048 | 0.0826 | 0.0210 | 0.1495 | 0.0494 | 0.1653 | 0.0539 | 0.1882 | 0.0764 | 0.3734 | 0.7940 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0000 | 0.0130 | 0.0021 | 0.0319 | 0.0109 | 0.0542 | 0.0231 | 0.0628 | 0.0163 | 0.0885 | 0.0251 | 0.7438 | 0.9226 | 0.0040 | 0.0078 | 0.0106 | 0.0142 | 0.0227 | 0.0492 | 0.0721 | 0.1410 | 0.1245 | 0.1643 | 0.1668 | 0.2018 | 0.1285 | 0.1294 | 0.1346 | 0.1345 | 0.3362 | 0.1578 | 0.0028 | 0.0044 | 0.0131 | 0.0331 | 0.0776 | 0.1130 | 0.1075 | 0.1367 | 0.5119 | 19 | 33 | 57 | 89 | 132 | 192 | 271 | 367 | 509 | 0.0106 | 35.88 | 6.248 | 0.3841 | 83484.1 | 45100000 | 28900000000 | 21200000000000 | 0.5547 | 0.1227 | 0.0456 | 0.0027 | 0.1805 | 0.0154 | 0.2495 | 0.1234 | 0.1651 | 0.1270 | 0.1294 | 0.1710 | 0.1041 | 0.1743 | 0.0548 | 0.1294 | 0.0370 | 0.1093 | 0.0339 | 0.1475 | 0.0005 | 0.0004 | 0.0013 | 0.0010 | 0.0037 | 0.0030 | 0.0122 | 0.0118 | 0.0659 | 0.0511 | 0.1064 | 0.0942 | 0.0799 | 0.0639 | 0.1109 | 0.0947 | 0.6192 | 0.6799 | 0.0004 | 0.0013 | 0.0022 | 0.0030 | 0.0061 | 0.0106 | 0.0230 | 0.0300 | 0.0848 | 0.0881 | 0.1339 | 0.1427 | 0.0916 | 0.1017 | 0.1258 | 0.1334 | 0.5322 | 0.4892 | 0.0002 | 0.0030 | 0.0037 | 0.0199 | 0.0732 | 0.1163 | 0.0904 | 0.1209 | 0.5723 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 944 | 643 | | 10766 | 25398 | 77.7 | 26.50 | 79.35 | 104.73 | 50 | 58 | 63 | 68 | 73 | 79 | 85 | 93 | 108 | 0.0568 | 1442 | 1.039 | 62.30 | 19.70 | 12 | 0.0144 | 155 | 0.0021 | 19.33 | 6.548 | 0.2687 | 6739.6 | 660302 | 73500000 | 9260000000 | 0.4514 | 0.1914 | 0.0004 | 0.0001 | 0.0041 | 0.0004 | 0.0155 | 0.0014 | 0.0404 | 0.0069 | 0.0933 | 0.0282 | 0.1426 | 0.0518 | 0.1465 | 0.0640 | 0.1811 | 0.0814 | 0.3762 | 0.7657 | 0.0003 | 0.0000 | 0.0017 | 0.0001 | 0.0045 | 0.0006 | 0.0160 | 0.0048 | 0.0422 | 0.0180 | 0.0703 | 0.0309 | 0.0638 | 0.0353 | 0.1024 | 0.0473 | 0.6987 | 0.8630 | 0.0039 | 0.0067 | 0.0111 | 0.0183 | 0.0261 | 0.0202 | 0.0623 | 0.0577 | 0.1044 | 0.0876 | 0.1358 | 0.1107 | 0.0894 | 0.0808 | 0.1049 | 0.1078 | 0.4621 | 0.5101 | 0.0018 | 0.0078 | 0.0155 | 0.0331 | 0.0750 | 0.0992 | 0.0965 | 0.1223 | 0.5488 | 24 | 27 | 31 | 34 | 39 | 47 | 64 | 99 | 187 | 0.1253 | 4.89 | 3.514 | 0.7026 | 17262.9 | 7360000 | 4380000000 | 3170000000000 | 0.5875 | 0.1331 | 0.0281 | 0.0053 | 0.1260 | 0.0156 | 0.1868 | 0.0425 | 0.1366 | 0.0966 | 0.1545 | 0.1560 | 0.1417 | 0.1683 | 0.1034 | 0.1305 | 0.0757 | 0.1316 | 0.0472 | 0.2536 | 0.0005 | 0.0026 | 0.0029 | 0.0056 | 0.0074 | 0.0082 | 0.0218 | 0.0211 | 0.0702 | 0.0565 | 0.0928 | 0.0744 | 0.0750 | 0.0686 | 0.1091 | 0.0987 | 0.6202 | 0.6644 | 0.0015 | 0.0009 | 0.0017 | 0.0024 | 0.0077 | 0.0079 | 0.0283 | 0.0323 | 0.0924 | 0.0996 | 0.1194 | 0.1287 | 0.0811 | 0.0910 | 0.1267 | 0.1337 | 0.5411 | 0.5034 | 0.0002 | 0.0021 | 0.0070 | 0.0280 | 0.0826 | 0.1089 | 0.0754 | 0.1199 | 0.5761 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 780 | 643 | | 4246 | 9503 | 153.2 | 43.23 | 163.95 | 111.35 | 107 | 118 | 127 | 135 | 144 | 155 | 167 | 184 | 213 | 0.0930 | 884 | 1.215 | 66.84 | 30.36 | 1 | 0.0445 | 189 | 0.0016 | 33.38 | 6.721 | 0.2068 | 25324.3 | 4540000 | 884000000 | 186000000000 | 0.4222 | 0.2177 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0065 | 0.0005 | 0.0285 | 0.0037 | 0.1085 | 0.0264 | 0.1876 | 0.0650 | 0.1746 | 0.0647 | 0.2040 | 0.0836 | 0.2891 | 0.7561 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0110 | 0.0012 | 0.0397 | 0.0171 | 0.0784 | 0.0293 | 0.0800 | 0.0238 | 0.1178 | 0.0358 | 0.6711 | 0.8927 | 0.0023 | 0.0000 | 0.0047 | 0.0049 | 0.0140 | 0.0196 | 0.0756 | 0.1225 | 0.1465 | 0.1716 | 0.1686 | 0.2059 | 0.1128 | 0.1152 | 0.1419 | 0.1127 | 0.3337 | 0.2475 | 0.0011 | 0.0022 | 0.0056 | 0.0332 | 0.0917 | 0.1507 | 0.1074 | 0.1277 | 0.4803 | 49 | 74 | 95 | 116 | 139 | 164 | 198 | 245 | 310 | 0.0019 | 44.15 | 6.783 | 0.2632 | 39278.6 | 12800000 | 5480000000 | 3000000000000 | 0.5562 | 0.1215 | 0.0241 | 0.0012 | 0.0805 | 0.0056 | 0.1411 | 0.0391 | 0.1416 | 0.0770 | 0.1754 | 0.1299 | 0.1546 | 0.1697 | 0.1157 | 0.1456 | 0.0995 | 0.1528 | 0.0676 | 0.2792 | 0.0014 | 0.0002 | 0.0026 | 0.0009 | 0.0069 | 0.0057 | 0.0242 | 0.0137 | 0.0746 | 0.0545 | 0.1063 | 0.0876 | 0.0950 | 0.0778 | 0.1295 | 0.1115 | 0.5595 | 0.6480 | 0.0031 | 0.0018 | 0.0045 | 0.0054 | 0.0118 | 0.0145 | 0.0478 | 0.0559 | 0.1069 | 0.1335 | 0.1491 | 0.1807 | 0.1301 | 0.1326 | 0.1557 | 0.1685 | 0.3910 | 0.3070 | 0.0018 | 0.0050 | 0.0089 | 0.0404 | 0.0908 | 0.1409 | 0.1049 | 0.1375 | 0.4699 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 999 | 759 | | 7014 | 22115 | 261.5 | 51.41 | 152.85 | 246.06 | 199 | 217 | 231 | 244 | 257 | 271 | 286 | 305 | 332 | 0.0572 | 1264 | 0.703 | 157.81 | 44.60 | 2 | 0.0720 | 505 | 0.0008 | 54.08 | 7.368 | 0.1589 | 71002.4 | 20000000 | 5820000000 | 1750000000000 | 0.4542 | 0.2013 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0198 | 0.0018 | 0.0614 | 0.0168 | 0.1165 | 0.0363 | 0.1431 | 0.0312 | 0.1561 | 0.0529 | 0.4986 | 0.8610 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0065 | 0.0007 | 0.0317 | 0.0127 | 0.0548 | 0.0245 | 0.0634 | 0.0171 | 0.0806 | 0.0298 | 0.7622 | 0.9151 | 0.0035 | 0.0142 | 0.0132 | 0.0474 | 0.0307 | 0.0664 | 0.0729 | 0.1232 | 0.1484 | 0.2133 | 0.1756 | 0.1706 | 0.1089 | 0.1611 | 0.1528 | 0.1137 | 0.2941 | 0.0900 | 0.0009 | 0.0021 | 0.0081 | 0.0332 | 0.0865 | 0.1293 | 0.1164 | 0.1320 | 0.4914 | 9 | 11 | 12 | 14 | 18 | 37 | 127 | 301 | 523 | 0.1005 | 52.42 | 4.809 | 0.5431 | 83904.9 | 63400000 | 57600000000 | 60200000000000 | 0.4909 | 0.1549 | 0.1011 | 0.0081 | 0.3100 | 0.0501 | 0.3478 | 0.2536 | 0.1133 | 0.2036 | 0.0800 | 0.1659 | 0.0233 | 0.1438 | 0.0122 | 0.0845 | 0.0067 | 0.0549 | 0.0056 | 0.0355 | 0.0001 | 0.0004 | 0.0009 | 0.0006 | 0.0022 | 0.0018 | 0.0097 | 0.0091 | 0.0460 | 0.0426 | 0.0824 | 0.0794 | 0.0515 | 0.0480 | 0.0790 | 0.0681 | 0.7281 | 0.7501 | 0.0000 | 0.0007 | 0.0015 | 0.0024 | 0.0028 | 0.0041 | 0.0143 | 0.0111 | 0.0528 | 0.0560 | 0.0945 | 0.1016 | 0.0625 | 0.0621 | 0.0883 | 0.0970 | 0.6834 | 0.6651 | 0.0003 | 0.0006 | 0.0019 | 0.0083 | 0.0525 | 0.0906 | 0.0541 | 0.0823 | 0.7093 |