High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 350 | 768 | | 2148 | 7377 | 649.8 | 190.42 | 59.61 | 108.11 | 361 | 467 | 544 | 624 | 689 | 729 | 767 | 811 | 863 | 0.0729 | 538 | 0.439 | 61.06 | 9.22 | 3 | 0.0791 | 170 | 0.0009 | 72.75 | 7.161 | 0.1651 | 458473.0 | 344000000 | 270000000000 | 221000000000000 | 0.4160 | 0.2058 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0006 | 0.0291 | 0.0023 | 0.0824 | 0.0283 | 0.1568 | 0.0702 | 0.1075 | 0.0385 | 0.1397 | 0.0645 | 0.4794 | 0.7957 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0016 | 0.0293 | 0.0240 | 0.0560 | 0.0464 | 0.0350 | 0.0235 | 0.0592 | 0.0427 | 0.8160 | 0.8617 | 0.0000 | 0.0094 | 0.0000 | 0.0283 | 0.0035 | 0.0189 | 0.0260 | 0.0566 | 0.0781 | 0.1415 | 0.1163 | 0.2264 | 0.0885 | 0.0472 | 0.1250 | 0.1038 | 0.5625 | 0.3679 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0432 | 0.0639 | 0.0490 | 0.0763 | 0.7585 | 7 | 9 | 11 | 13 | 16 | 21 | 32 | 64 | 203 | 0.0746 | 10.49 | 3.983 | 0.6307 | 15239.4 | 6560000 | 3660000000 | 2420000000000 | 0.2920 | 0.3302 | 0.0000 | 0.0050 | 0.0655 | 0.0113 | 0.2143 | 0.0239 | 0.2292 | 0.0642 | 0.2054 | 0.1597 | 0.1429 | 0.2013 | 0.0774 | 0.1660 | 0.0506 | 0.1698 | 0.0149 | 0.1987 | 0.0000 | 0.0019 | 0.0017 | 0.0043 | 0.0040 | 0.0038 | 0.0115 | 0.0125 | 0.0340 | 0.0355 | 0.0530 | 0.0485 | 0.0363 | 0.0384 | 0.0594 | 0.0677 | 0.8000 | 0.7872 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0031 | 0.0129 | 0.0109 | 0.0372 | 0.0427 | 0.0558 | 0.0637 | 0.0393 | 0.0365 | 0.0629 | 0.0637 | 0.7877 | 0.7793 | 0.0000 | 0.0000 | 0.0007 | 0.0170 | 0.0352 | 0.0483 | 0.0463 | 0.0614 | 0.7911 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 526 | 612 | | 4592 | 11096 | 714.2 | 99.82 | 91.74 | 166.81 | 589 | 634 | 669 | 693 | 712 | 732 | 756 | 790 | 865 | 0.0617 | 685 | 1.192 | 82.49 | 32.31 | 1 | 0.0464 | 213 | 0.0012 | 39.16 | 7.036 | 0.2240 | 520098.0 | 386000000 | 291000000000 | 223000000000000 | 0.3926 | 0.2577 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0024 | 0.0000 | 0.0078 | 0.0000 | 0.0202 | 0.0126 | 0.0427 | 0.0244 | 0.0333 | 0.0109 | 0.0462 | 0.0196 | 0.8444 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0120 | 0.0126 | 0.0271 | 0.0244 | 0.0165 | 0.0109 | 0.0268 | 0.0196 | 0.9153 | 0.9324 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0000 | 0.0285 | 0.0000 | 0.0645 | 0.0000 | 0.1082 | 0.0000 | 0.1176 | 0.0000 | 0.1442 | 0.0000 | 0.5237 | 0.0000 | 0.0022 | 0.0027 | 0.0111 | 0.0200 | 0.0408 | 0.0616 | 0.0585 | 0.0789 | 0.7242 | 7 | 9 | 10 | 13 | 19 | 35 | 59 | 122 | 282 | 0.1396 | 15.62 | 3.866 | 0.6295 | 36238.5 | 22600000 | 17000000000 | 14400000000000 | 0.4303 | 0.1803 | 0.0541 | 0.0062 | 0.1723 | 0.0346 | 0.2804 | 0.0892 | 0.1486 | 0.1277 | 0.1216 | 0.1600 | 0.0912 | 0.1738 | 0.0456 | 0.1138 | 0.0372 | 0.1200 | 0.0490 | 0.1746 | 0.0007 | 0.0006 | 0.0014 | 0.0026 | 0.0061 | 0.0038 | 0.0208 | 0.0191 | 0.0546 | 0.0430 | 0.0869 | 0.0774 | 0.0440 | 0.0543 | 0.0617 | 0.0676 | 0.7238 | 0.7317 | 0.0009 | 0.0009 | 0.0021 | 0.0023 | 0.0081 | 0.0069 | 0.0214 | 0.0236 | 0.0585 | 0.0573 | 0.0880 | 0.0906 | 0.0440 | 0.0495 | 0.0679 | 0.0703 | 0.7091 | 0.6986 | 0.0008 | 0.0015 | 0.0073 | 0.0191 | 0.0546 | 0.0863 | 0.0454 | 0.0569 | 0.7281 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 644 | 509 | | 752 | 2601 | 109.3 | 22.70 | 27.66 | 36.83 | 79 | 89 | 97 | 104 | 110 | 117 | 123 | 130 | 139 | 0.1303 | 339 | 0.980 | 171.76 | 54.15 | 1 | 0.6197 | 466 | 0.0023 | 47.96 | 6.181 | 0.1607 | 12466.6 | 1470000 | 179000000 | 22400000000 | 0.3827 | 0.2423 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0151 | 0.0000 | 0.0538 | 0.0042 | 0.1075 | 0.0379 | 0.1613 | 0.0618 | 0.1527 | 0.0520 | 0.2022 | 0.0758 | 0.3032 | 0.7683 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0114 | 0.0041 | 0.0507 | 0.0346 | 0.0654 | 0.0553 | 0.0670 | 0.0346 | 0.1029 | 0.0581 | 0.7010 | 0.8133 | 0.0204 | 0.0000 | 0.0272 | 0.0909 | 0.0612 | 0.3636 | 0.0952 | 0.2727 | 0.1837 | 0.0909 | 0.1361 | 0.1818 | 0.1633 | 0.0000 | 0.1769 | 0.0000 | 0.1361 | 0.0000 | 0.0000 | 0.0025 | 0.0101 | 0.0404 | 0.0783 | 0.1364 | 0.1364 | 0.1338 | 0.4621 | 13 | 14 | 15 | 16 | 17 | 18 | 21 | 29 | 50 | 0.5312 | 1.01 | 1.471 | 0.9002 | 2121.0 | 439440 | 138000000 | 49900000000 | 0.6286 | 0.0988 | 0.0545 | 0.0328 | 0.0955 | 0.0864 | 0.2136 | 0.1351 | 0.2136 | 0.1033 | 0.1727 | 0.1360 | 0.1091 | 0.1360 | 0.0909 | 0.1241 | 0.0364 | 0.1311 | 0.0136 | 0.1152 | 0.0104 | 0.0219 | 0.0104 | 0.0629 | 0.0207 | 0.0950 | 0.0370 | 0.0673 | 0.1111 | 0.0994 | 0.1156 | 0.0892 | 0.1319 | 0.1001 | 0.1452 | 0.1235 | 0.4178 | 0.3406 | 0.0000 | 0.0000 | 0.0022 | 0.0249 | 0.0198 | 0.0305 | 0.0440 | 0.0693 | 0.1604 | 0.1662 | 0.1758 | 0.1801 | 0.1297 | 0.1468 | 0.1714 | 0.1634 | 0.2967 | 0.2188 | 0.0036 | 0.0073 | 0.0146 | 0.0419 | 0.1421 | 0.1512 | 0.1275 | 0.1658 | 0.3461 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 703 | 330 | | 1517 | 7267 | 260.9 | 69.91 | 59.78 | 117.99 | 178 | 191 | 206 | 227 | 248 | 274 | 304 | 331 | 369 | 0.0860 | 625 | 1.115 | 107.79 | 38.05 | 1 | 0.1793 | 272 | 0.0105 | 1.72 | 4.763 | 0.5649 | 72953.0 | 21700000 | 6830000000 | 2240000000000 | 0.3508 | 0.2996 | 0.0016 | 0.0000 | 0.0031 | 0.0000 | 0.0062 | 0.0015 | 0.0171 | 0.0067 | 0.0715 | 0.0340 | 0.0964 | 0.0503 | 0.1026 | 0.0392 | 0.1291 | 0.0673 | 0.5723 | 0.8010 | 0.0010 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0040 | 0.0306 | 0.0224 | 0.0373 | 0.0369 | 0.0335 | 0.0257 | 0.0450 | 0.0383 | 0.8431 | 0.8727 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0061 | 0.0124 | 0.0549 | 0.0423 | 0.0610 | 0.0547 | 0.0549 | 0.0448 | 0.1220 | 0.0821 | 0.0854 | 0.7512 | 0.6159 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0337 | 0.0527 | 0.0366 | 0.0439 | 0.8228 | 7 | 8 | 9 | 10 | 11 | 15 | 28 | 57 | 188 | 0.1752 | 2.71 | 2.781 | 0.6871 | 17493.2 | 7830000 | 4090000000 | 2340000000000 | 0.4255 | 0.2007 | 0.0273 | 0.0043 | 0.0648 | 0.0086 | 0.1297 | 0.0114 | 0.2150 | 0.0643 | 0.2116 | 0.1186 | 0.1502 | 0.1686 | 0.1229 | 0.1429 | 0.0614 | 0.1629 | 0.0171 | 0.3186 | 0.0031 | 0.0010 | 0.0037 | 0.0021 | 0.0074 | 0.0026 | 0.0155 | 0.0129 | 0.0372 | 0.0290 | 0.0440 | 0.0403 | 0.0415 | 0.0445 | 0.0551 | 0.0672 | 0.7926 | 0.8004 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0023 | 0.0024 | 0.0053 | 0.0097 | 0.0371 | 0.0308 | 0.0393 | 0.0559 | 0.0446 | 0.0454 | 0.0598 | 0.0608 | 0.8086 | 0.7950 | 0.0000 | 0.0021 | 0.0049 | 0.0119 | 0.0295 | 0.0372 | 0.0400 | 0.0534 | 0.8209 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1262 | 191 | | 1146 | 5093 | 90.2 | 37.96 | 173.01 | 291.74 | 37 | 56 | 70 | 80 | 89 | 98 | 108 | 122 | 139 | 0.1056 | 538 | 0.246 | 326.81 | 58.25 | 3 | 1.2321 | 1412 | 0.0022 | 29.57 | 6.284 | 0.2125 | 9584.0 | 1150000 | 154000000 | 22500000000 | 0.3879 | 0.2271 | 0.0045 | 0.0000 | 0.0182 | 0.0000 | 0.0795 | 0.0040 | 0.0932 | 0.0173 | 0.1295 | 0.0840 | 0.1705 | 0.1280 | 0.1705 | 0.1333 | 0.1955 | 0.1453 | 0.1386 | 0.4880 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0064 | 0.0032 | 0.0446 | 0.0319 | 0.0841 | 0.0554 | 0.0828 | 0.0405 | 0.1338 | 0.0692 | 0.6459 | 0.7998 | 0.0000 | 0.0106 | 0.0087 | 0.0212 | 0.0203 | 0.0159 | 0.0580 | 0.0847 | 0.1130 | 0.2328 | 0.1652 | 0.2011 | 0.1275 | 0.1164 | 0.1739 | 0.1270 | 0.3333 | 0.1905 | 0.0035 | 0.0018 | 0.0089 | 0.0319 | 0.0904 | 0.1294 | 0.1188 | 0.1489 | 0.4663 | 14 | 16 | 18 | 21 | 25 | 39 | 104 | 323 | 583 | 0.0764 | 34.57 | 4.571 | 0.5346 | 115023.0 | 109000000 | 127000000000 | 170000000000000 | 0.7263 | 0.0444 | 0.0738 | 0.0122 | 0.3020 | 0.0550 | 0.3087 | 0.1498 | 0.1477 | 0.2385 | 0.1208 | 0.2599 | 0.0201 | 0.1346 | 0.0134 | 0.0642 | 0.0134 | 0.0367 | 0.0000 | 0.0489 | 0.0000 | 0.0007 | 0.0028 | 0.0013 | 0.0028 | 0.0033 | 0.0264 | 0.0209 | 0.0674 | 0.0712 | 0.1035 | 0.0935 | 0.0757 | 0.0745 | 0.1070 | 0.1085 | 0.6143 | 0.6261 | 0.0016 | 0.0000 | 0.0023 | 0.0025 | 0.0047 | 0.0183 | 0.0287 | 0.0241 | 0.0636 | 0.0665 | 0.1116 | 0.1155 | 0.0853 | 0.0840 | 0.1124 | 0.1139 | 0.5899 | 0.5752 | 0.0007 | 0.0029 | 0.0066 | 0.0269 | 0.0655 | 0.1077 | 0.0852 | 0.1033 | 0.6012 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 577 | 529 | | 6874 | 21430 | 274.4 | 54.77 | 116.67 | 134.04 | 206 | 226 | 242 | 256 | 270 | 284 | 301 | 322 | 348 | 0.0497 | 1066 | 0.952 | 129.08 | 32.53 | 1 | 0.0428 | 294 | 0.0008 | 54.60 | 7.392 | 0.1620 | 78288.9 | 23200000 | 7120000000 | 2260000000000 | 0.4124 | 0.2339 | 0.0007 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0002 | 0.0146 | 0.0009 | 0.0620 | 0.0167 | 0.1265 | 0.0357 | 0.1468 | 0.0339 | 0.1774 | 0.0560 | 0.4691 | 0.8567 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0052 | 0.0007 | 0.0245 | 0.0114 | 0.0505 | 0.0239 | 0.0545 | 0.0147 | 0.0759 | 0.0202 | 0.7879 | 0.9290 | 0.0068 | 0.0346 | 0.0101 | 0.0260 | 0.0245 | 0.1126 | 0.0785 | 0.1472 | 0.1647 | 0.2338 | 0.1976 | 0.1515 | 0.1309 | 0.1126 | 0.1512 | 0.1169 | 0.2356 | 0.0649 | 0.0012 | 0.0000 | 0.0080 | 0.0316 | 0.0807 | 0.1133 | 0.1072 | 0.1308 | 0.5272 | 10 | 13 | 16 | 28 | 55 | 99 | 154 | 222 | 315 | 0.0595 | 13.88 | 5.027 | 0.5286 | 31578.4 | 11600000 | 5190000000 | 2690000000000 | 0.5015 | 0.1536 | 0.0506 | 0.0016 | 0.2117 | 0.0180 | 0.3416 | 0.0886 | 0.1686 | 0.1769 | 0.1002 | 0.2501 | 0.0717 | 0.1846 | 0.0372 | 0.1200 | 0.0151 | 0.0904 | 0.0032 | 0.0698 | 0.0001 | 0.0000 | 0.0006 | 0.0005 | 0.0015 | 0.0008 | 0.0076 | 0.0083 | 0.0547 | 0.0435 | 0.0986 | 0.0770 | 0.0711 | 0.0601 | 0.1113 | 0.0927 | 0.6546 | 0.7171 | 0.0003 | 0.0007 | 0.0017 | 0.0016 | 0.0030 | 0.0034 | 0.0156 | 0.0219 | 0.0765 | 0.0905 | 0.1334 | 0.1420 | 0.0961 | 0.1062 | 0.1363 | 0.1430 | 0.5370 | 0.4906 | 0.0003 | 0.0010 | 0.0023 | 0.0117 | 0.0625 | 0.1168 | 0.0835 | 0.1295 | 0.5924 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 273 | 873 | | 959 | 20054 | 113.6 | 15.41 | 28.35 | 38.32 | 95 | 99 | 103 | 107 | 113 | 117 | 121 | 127 | 135 | 0.0524 | 1050 | 1.034 | 39.40 | 13.04 | 0 | 0.1064 | 102 | 0.0763 | 0.50 | 2.832 | 0.7708 | 13136.1 | 1550000 | 186000000 | 22800000000 | 0.4056 | 0.2400 | 0.0012 | 0.0000 | 0.0036 | 0.0010 | 0.0083 | 0.0031 | 0.0154 | 0.0073 | 0.0473 | 0.0241 | 0.0746 | 0.0640 | 0.0734 | 0.0325 | 0.1006 | 0.0598 | 0.6757 | 0.8080 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0076 | 0.0031 | 0.0108 | 0.0073 | 0.0314 | 0.0229 | 0.0541 | 0.0615 | 0.0400 | 0.0250 | 0.0639 | 0.0532 | 0.7879 | 0.8259 | 0.0000 | 0.0000 | 0.0127 | 0.1667 | 0.0506 | 0.0000 | 0.1013 | 0.5000 | 0.1266 | 0.3333 | 0.1392 | 0.0000 | 0.1266 | 0.0000 | 0.1266 | 0.0000 | 0.3165 | 0.0000 | 0.0022 | 0.0043 | 0.0152 | 0.0260 | 0.0390 | 0.0758 | 0.0736 | 0.1017 | 0.6623 | 11 | 13 | 15 | 17 | 20 | 22 | 26 | 31 | 40 | 0.3245 | 0.91 | 1.880 | 0.8551 | 2272.4 | 507754 | 174000000 | 71000000000 | 0.5696 | 0.1296 | 0.0433 | 0.0176 | 0.0600 | 0.0218 | 0.0785 | 0.0264 | 0.1039 | 0.0386 | 0.1265 | 0.0642 | 0.1678 | 0.0809 | 0.1887 | 0.1079 | 0.1421 | 0.1846 | 0.0893 | 0.4581 | 0.0240 | 0.0144 | 0.0282 | 0.0178 | 0.0330 | 0.0204 | 0.0353 | 0.0280 | 0.0502 | 0.0467 | 0.0618 | 0.0603 | 0.0746 | 0.0721 | 0.1061 | 0.1150 | 0.5867 | 0.6253 | 0.0284 | 0.0348 | 0.0315 | 0.0221 | 0.0495 | 0.0172 | 0.0486 | 0.0255 | 0.0769 | 0.0594 | 0.0874 | 0.0790 | 0.0867 | 0.0795 | 0.1126 | 0.1286 | 0.4784 | 0.5540 | 0.0222 | 0.0261 | 0.0286 | 0.0380 | 0.0551 | 0.0752 | 0.0968 | 0.1505 | 0.5076 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 718 | 209 | | 6919 | 20153 | 439.9 | 83.94 | 59.12 | 60.79 | 328 | 364 | 393 | 418 | 442 | 465 | 486 | 511 | 544 | 0.0555 | 1118 | 1.097 | 116.93 | 36.89 | 1 | 0.0405 | 280 | 0.0010 | 31.34 | 7.121 | 0.1942 | 200514.0 | 94500000 | 45900000000 | 23000000000000 | 0.3868 | 0.2525 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0112 | 0.0015 | 0.0437 | 0.0118 | 0.0766 | 0.0244 | 0.0951 | 0.0209 | 0.1280 | 0.0268 | 0.6427 | 0.9146 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0013 | 0.0171 | 0.0100 | 0.0281 | 0.0194 | 0.0344 | 0.0128 | 0.0426 | 0.0172 | 0.8730 | 0.9393 | 0.0040 | 0.0086 | 0.0081 | 0.0000 | 0.0424 | 0.0259 | 0.0727 | 0.2586 | 0.1354 | 0.0862 | 0.1687 | 0.1810 | 0.1343 | 0.1293 | 0.1384 | 0.0431 | 0.2960 | 0.2672 | 0.0003 | 0.0014 | 0.0020 | 0.0108 | 0.0519 | 0.0935 | 0.0896 | 0.1278 | 0.6227 | 8 | 10 | 14 | 25 | 40 | 57 | 76 | 99 | 135 | 0.0457 | 4.18 | 4.483 | 0.5799 | 7190.4 | 1330000 | 338000000 | 109000000000 | 0.4299 | 0.1814 | 0.0071 | 0.0015 | 0.0560 | 0.0042 | 0.1504 | 0.0171 | 0.2041 | 0.0543 | 0.2237 | 0.1277 | 0.1653 | 0.2005 | 0.1077 | 0.1668 | 0.0611 | 0.1704 | 0.0247 | 0.2575 | 0.0002 | 0.0001 | 0.0009 | 0.0008 | 0.0023 | 0.0018 | 0.0122 | 0.0087 | 0.0364 | 0.0271 | 0.0609 | 0.0475 | 0.0552 | 0.0389 | 0.0755 | 0.0611 | 0.7565 | 0.8141 | 0.0011 | 0.0011 | 0.0026 | 0.0037 | 0.0041 | 0.0073 | 0.0192 | 0.0257 | 0.0575 | 0.0690 | 0.0847 | 0.1021 | 0.0802 | 0.0802 | 0.1038 | 0.1182 | 0.6468 | 0.5927 | 0.0005 | 0.0010 | 0.0038 | 0.0132 | 0.0444 | 0.0754 | 0.0604 | 0.0891 | 0.7123 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 266 | 404 | | 2278 | 9177 | 440.8 | 82.93 | 18.18 | 14.33 | 329 | 363 | 393 | 419 | 442 | 462 | 484 | 509 | 554 | 0.0623 | 572 | 0.857 | 85.43 | 24.17 | 1 | 0.0979 | 223 | 0.0015 | 22.45 | 6.709 | 0.2343 | 201189.0 | 94800000 | 46100000000 | 23000000000000 | 0.3824 | 0.2567 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0000 | 0.0102 | 0.0013 | 0.0447 | 0.0224 | 0.0735 | 0.0385 | 0.0671 | 0.0251 | 0.0927 | 0.0354 | 0.7073 | 0.8772 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0042 | 0.0004 | 0.0221 | 0.0184 | 0.0390 | 0.0347 | 0.0269 | 0.0158 | 0.0421 | 0.0237 | 0.8635 | 0.9069 | 0.0030 | 0.0222 | 0.0090 | 0.0000 | 0.0270 | 0.0889 | 0.0450 | 0.0889 | 0.0601 | 0.2000 | 0.1141 | 0.1333 | 0.1171 | 0.1778 | 0.1081 | 0.1333 | 0.5165 | 0.1556 | 0.0000 | 0.0009 | 0.0035 | 0.0130 | 0.0496 | 0.0696 | 0.0600 | 0.0904 | 0.7130 | 9 | 11 | 12 | 14 | 15 | 17 | 19 | 22 | 28 | 0.2118 | 0.79 | 1.993 | 0.8257 | 536.0 | 35898.2 | 4390000 | 666000000 | 0.5182 | 0.1416 | 0.0551 | 0.0050 | 0.0834 | 0.0121 | 0.1015 | 0.0296 | 0.1367 | 0.0539 | 0.1535 | 0.0819 | 0.1890 | 0.1115 | 0.1671 | 0.1301 | 0.0914 | 0.1928 | 0.0223 | 0.3829 | 0.0260 | 0.0018 | 0.0361 | 0.0067 | 0.0367 | 0.0183 | 0.0476 | 0.0364 | 0.0429 | 0.0592 | 0.0677 | 0.0813 | 0.0851 | 0.0830 | 0.1435 | 0.1084 | 0.5144 | 0.6048 | 0.0291 | 0.0429 | 0.0530 | 0.0429 | 0.0540 | 0.0429 | 0.0673 | 0.0648 | 0.0726 | 0.0843 | 0.1017 | 0.1199 | 0.0984 | 0.1240 | 0.1437 | 0.1337 | 0.3801 | 0.3444 | 0.0322 | 0.0313 | 0.0342 | 0.0453 | 0.0664 | 0.0914 | 0.1047 | 0.1395 | 0.4549 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 164 | 879 | | 4050 | 8872 | 419.4 | 110.73 | 86.10 | 234.18 | 295 | 334 | 362 | 385 | 409 | 439 | 474 | 515 | 570 | 0.0979 | 869 | 0.960 | 155.00 | 54.01 | 3 | 0.1049 | 425 | 0.0007 | 76.29 | 7.489 | 0.1602 | 188142.0 | 89200000 | 44400000000 | 23100000000000 | 0.4137 | 0.2255 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0052 | 0.0000 | 0.0231 | 0.0043 | 0.0718 | 0.0210 | 0.1144 | 0.0459 | 0.1271 | 0.0397 | 0.1462 | 0.0559 | 0.5100 | 0.8333 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0071 | 0.0013 | 0.0298 | 0.0149 | 0.0481 | 0.0238 | 0.0528 | 0.0149 | 0.0708 | 0.0245 | 0.7886 | 0.9206 | 0.0011 | 0.0000 | 0.0043 | 0.0099 | 0.0130 | 0.0099 | 0.0444 | 0.0759 | 0.0704 | 0.1452 | 0.1083 | 0.1716 | 0.0986 | 0.1089 | 0.1073 | 0.1584 | 0.5525 | 0.3201 | 0.0016 | 0.0032 | 0.0111 | 0.0185 | 0.0506 | 0.0749 | 0.0611 | 0.0870 | 0.6921 | 11 | 12 | 14 | 15 | 16 | 17 | 20 | 35 | 226 | 0.4982 | 14.49 | 2.220 | 0.8059 | 62249.3 | 81200000 | 135000000000 | 258000000000000 | 0.6303 | 0.0763 | 0.2131 | 0.0132 | 0.4262 | 0.1376 | 0.2295 | 0.3995 | 0.0546 | 0.1508 | 0.0546 | 0.1164 | 0.0219 | 0.1085 | 0.0000 | 0.0423 | 0.0000 | 0.0265 | 0.0000 | 0.0053 | 0.0007 | 0.0006 | 0.0055 | 0.0019 | 0.0097 | 0.0070 | 0.0194 | 0.0171 | 0.0947 | 0.0912 | 0.1418 | 0.1476 | 0.0705 | 0.0646 | 0.0961 | 0.0956 | 0.5615 | 0.5744 | 0.0008 | 0.0008 | 0.0032 | 0.0042 | 0.0071 | 0.0100 | 0.0301 | 0.0308 | 0.1013 | 0.1032 | 0.1362 | 0.1424 | 0.0831 | 0.0849 | 0.1077 | 0.1091 | 0.5305 | 0.5146 | 0.0022 | 0.0037 | 0.0066 | 0.0176 | 0.1051 | 0.1412 | 0.0713 | 0.1037 | 0.5485 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 826 | 768 | | 6744 | 16336 | 268.2 | 71.69 | 141.22 | 168.95 | 172 | 220 | 244 | 260 | 275 | 290 | 307 | 325 | 352 | 0.0586 | 958 | 0.774 | 134.30 | 33.11 | 3 | 0.0550 | 371 | 0.0010 | 38.65 | 7.160 | 0.1905 | 77081.5 | 23200000 | 7220000000 | 2320000000000 | 0.3771 | 0.2521 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0000 | 0.0202 | 0.0010 | 0.0641 | 0.0201 | 0.1133 | 0.0421 | 0.1271 | 0.0409 | 0.1690 | 0.0603 | 0.5009 | 0.8356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0022 | 0.0003 | 0.0193 | 0.0134 | 0.0351 | 0.0215 | 0.0430 | 0.0137 | 0.0639 | 0.0228 | 0.8363 | 0.9283 | 0.0020 | 0.0031 | 0.0094 | 0.0282 | 0.0201 | 0.0627 | 0.0602 | 0.1818 | 0.1145 | 0.1567 | 0.1667 | 0.2382 | 0.1245 | 0.1160 | 0.1506 | 0.1097 | 0.3521 | 0.1034 | 0.0005 | 0.0016 | 0.0054 | 0.0231 | 0.0549 | 0.0995 | 0.1012 | 0.1118 | 0.6018 | 11 | 13 | 17 | 33 | 74 | 117 | 174 | 256 | 384 | 0.1123 | 13.02 | 4.544 | 0.6051 | 48483.6 | 23400000 | 14000000000 | 9870000000000 | 0.3529 | 0.3072 | 0.0233 | 0.0006 | 0.0993 | 0.0098 | 0.1771 | 0.0540 | 0.1646 | 0.0816 | 0.1538 | 0.1403 | 0.1514 | 0.1788 | 0.0946 | 0.1438 | 0.0814 | 0.1444 | 0.0545 | 0.2467 | 0.0000 | 0.0000 | 0.0010 | 0.0014 | 0.0024 | 0.0015 | 0.0118 | 0.0068 | 0.0392 | 0.0287 | 0.0668 | 0.0517 | 0.0535 | 0.0373 | 0.0764 | 0.0617 | 0.7488 | 0.8108 | 0.0006 | 0.0011 | 0.0012 | 0.0025 | 0.0052 | 0.0039 | 0.0226 | 0.0215 | 0.0569 | 0.0753 | 0.0967 | 0.1142 | 0.0841 | 0.1007 | 0.1157 | 0.1304 | 0.6171 | 0.5504 | 0.0003 | 0.0014 | 0.0036 | 0.0128 | 0.0544 | 0.0778 | 0.0679 | 0.0958 | 0.6859 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 797 | 276 | | 3081 | 14857 | 257.1 | 73.60 | 95.99 | 124.19 | 175 | 187 | 202 | 218 | 241 | 266 | 296 | 325 | 367 | 0.0703 | 1045 | 0.709 | 60.54 | 16.03 | 2 | 0.0568 | 175 | 0.0097 | 3.01 | 5.047 | 0.5308 | 71538.3 | 21500000 | 6880000000 | 2330000000000 | 0.3683 | 0.2682 | 0.0023 | 0.0000 | 0.0053 | 0.0000 | 0.0107 | 0.0015 | 0.0328 | 0.0041 | 0.0710 | 0.0354 | 0.1154 | 0.0479 | 0.1054 | 0.0420 | 0.1398 | 0.0593 | 0.5172 | 0.8099 | 0.0014 | 0.0000 | 0.0019 | 0.0000 | 0.0043 | 0.0007 | 0.0125 | 0.0013 | 0.0288 | 0.0202 | 0.0389 | 0.0276 | 0.0408 | 0.0189 | 0.0504 | 0.0315 | 0.8209 | 0.8998 | 0.0013 | 0.0000 | 0.0000 | 0.0111 | 0.0090 | 0.0028 | 0.0168 | 0.0306 | 0.0530 | 0.0889 | 0.0917 | 0.1306 | 0.0646 | 0.1139 | 0.0904 | 0.1500 | 0.6731 | 0.4722 | 0.0015 | 0.0015 | 0.0052 | 0.0126 | 0.0238 | 0.0535 | 0.0416 | 0.0558 | 0.8045 | 12 | 19 | 29 | 42 | 54 | 70 | 95 | 135 | 230 | 0.0663 | 4.54 | 3.869 | 0.7237 | 24635.6 | 11400000 | 7270000000 | 5520000000000 | 0.4425 | 0.1810 | 0.0092 | 0.0039 | 0.0252 | 0.0102 | 0.0406 | 0.0158 | 0.0729 | 0.0304 | 0.1237 | 0.0621 | 0.1566 | 0.0900 | 0.1494 | 0.0954 | 0.1869 | 0.1280 | 0.2356 | 0.5641 | 0.0025 | 0.0017 | 0.0033 | 0.0049 | 0.0040 | 0.0052 | 0.0113 | 0.0100 | 0.0302 | 0.0240 | 0.0458 | 0.0344 | 0.0473 | 0.0408 | 0.0691 | 0.0611 | 0.7864 | 0.8179 | 0.0008 | 0.0007 | 0.0034 | 0.0027 | 0.0059 | 0.0050 | 0.0163 | 0.0174 | 0.0487 | 0.0557 | 0.0704 | 0.0795 | 0.0637 | 0.0651 | 0.0789 | 0.0849 | 0.7118 | 0.6890 | 0.0011 | 0.0052 | 0.0059 | 0.0142 | 0.0363 | 0.0542 | 0.0582 | 0.0716 | 0.7533 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 840 | 632 | | 7599 | 25331 | 439.9 | 83.79 | 168.72 | 276.45 | 340 | 369 | 390 | 410 | 429 | 450 | 476 | 508 | 555 | 0.0492 | 1247 | 1.002 | 122.50 | 43.46 | 1 | 0.0425 | 323 | 0.0006 | 77.97 | 7.638 | 0.1430 | 200554.0 | 94700000 | 46300000000 | 23400000000000 | 0.4550 | 0.1957 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0026 | 0.0000 | 0.0094 | 0.0007 | 0.0535 | 0.0144 | 0.1165 | 0.0319 | 0.1324 | 0.0357 | 0.1602 | 0.0471 | 0.5253 | 0.8703 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0278 | 0.0111 | 0.0578 | 0.0182 | 0.0625 | 0.0137 | 0.0881 | 0.0211 | 0.7604 | 0.9358 | 0.0025 | 0.0077 | 0.0101 | 0.0193 | 0.0126 | 0.0386 | 0.0666 | 0.2278 | 0.1265 | 0.2162 | 0.1678 | 0.2355 | 0.1273 | 0.1042 | 0.1669 | 0.0965 | 0.3196 | 0.0541 | 0.0012 | 0.0026 | 0.0096 | 0.0417 | 0.0858 | 0.1214 | 0.1033 | 0.1219 | 0.5125 | 6 | 7 | 9 | 11 | 16 | 45 | 143 | 328 | 583 | 0.1315 | 51.22 | 4.587 | 0.5228 | 104886.0 | 87500000 | 85800000000 | 94300000000000 | 0.5042 | 0.1314 | 0.1174 | 0.0045 | 0.3070 | 0.0508 | 0.2798 | 0.2324 | 0.1277 | 0.2165 | 0.1108 | 0.1884 | 0.0404 | 0.1303 | 0.0113 | 0.0944 | 0.0038 | 0.0477 | 0.0019 | 0.0350 | 0.0001 | 0.0001 | 0.0012 | 0.0004 | 0.0026 | 0.0011 | 0.0093 | 0.0084 | 0.0522 | 0.0465 | 0.0772 | 0.0740 | 0.0532 | 0.0513 | 0.0848 | 0.0734 | 0.7194 | 0.7448 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0021 | 0.0027 | 0.0093 | 0.0091 | 0.0560 | 0.0627 | 0.0918 | 0.1001 | 0.0656 | 0.0705 | 0.1066 | 0.1206 | 0.6678 | 0.6332 | 0.0003 | 0.0015 | 0.0032 | 0.0089 | 0.0529 | 0.0819 | 0.0600 | 0.0898 | 0.7015 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 462 | | 6757 | 10694 | 103.6 | 26.81 | 127.16 | 113.08 | 75 | 82 | 88 | 93 | 98 | 104 | 112 | 123 | 140 | 0.0902 | 965 | 1.167 | 103.82 | 31.40 | 1 | 0.0364 | 246 | 0.0039 | 11.91 | 5.964 | 0.3215 | 11459.3 | 1360000 | 172000000 | 23500000000 | 0.4214 | 0.2299 | 0.0010 | 0.0000 | 0.0030 | 0.0000 | 0.0088 | 0.0010 | 0.0340 | 0.0029 | 0.0862 | 0.0218 | 0.1582 | 0.0506 | 0.1512 | 0.0465 | 0.1907 | 0.0759 | 0.3668 | 0.8013 | 0.0006 | 0.0000 | 0.0013 | 0.0000 | 0.0044 | 0.0003 | 0.0169 | 0.0005 | 0.0417 | 0.0128 | 0.0730 | 0.0254 | 0.0763 | 0.0197 | 0.1012 | 0.0369 | 0.6846 | 0.9045 | 0.0039 | 0.0036 | 0.0093 | 0.0000 | 0.0171 | 0.0342 | 0.0497 | 0.0739 | 0.0994 | 0.1586 | 0.1654 | 0.2036 | 0.1165 | 0.1243 | 0.1405 | 0.1333 | 0.3983 | 0.2685 | 0.0040 | 0.0058 | 0.0112 | 0.0426 | 0.0834 | 0.1119 | 0.0888 | 0.1241 | 0.5283 | 17 | 32 | 49 | 71 | 97 | 124 | 158 | 204 | 276 | 0.0049 | 28.88 | 6.477 | 0.3379 | 28954.2 | 9110000 | 3510000000 | 1540000000000 | 0.5010 | 0.1908 | 0.0104 | 0.0014 | 0.0825 | 0.0080 | 0.1622 | 0.0280 | 0.1715 | 0.0704 | 0.1802 | 0.1431 | 0.1846 | 0.1949 | 0.0978 | 0.1574 | 0.0672 | 0.1528 | 0.0437 | 0.2441 | 0.0002 | 0.0005 | 0.0006 | 0.0006 | 0.0043 | 0.0027 | 0.0166 | 0.0116 | 0.0621 | 0.0488 | 0.1025 | 0.0778 | 0.0847 | 0.0716 | 0.1177 | 0.0936 | 0.6114 | 0.6925 | 0.0027 | 0.0022 | 0.0036 | 0.0056 | 0.0141 | 0.0086 | 0.0335 | 0.0365 | 0.0847 | 0.0941 | 0.1182 | 0.1391 | 0.0972 | 0.0926 | 0.1152 | 0.1183 | 0.5308 | 0.5030 | 0.0007 | 0.0021 | 0.0060 | 0.0293 | 0.0767 | 0.1199 | 0.0870 | 0.1146 | 0.5636 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 469 | 396 | | 3985 | 3374 | 160.1 | 46.65 | 190.25 | 141.76 | 107 | 121 | 132 | 142 | 153 | 165 | 177 | 195 | 221 | 0.2110 | 712 | 0.988 | 83.24 | 28.02 | 1 | 0.0575 | 229 | 0.0012 | 50.08 | 6.991 | 0.1783 | 27806.5 | 5240000 | 1070000000 | 235000000000 | 0.4379 | 0.2135 | 0.0010 | 0.0000 | 0.0005 | 0.0000 | 0.0144 | 0.0017 | 0.0460 | 0.0032 | 0.1321 | 0.0326 | 0.1991 | 0.0843 | 0.1709 | 0.0837 | 0.1728 | 0.1160 | 0.2633 | 0.6784 | 0.0007 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0003 | 0.0098 | 0.0016 | 0.0480 | 0.0199 | 0.0912 | 0.0482 | 0.0784 | 0.0364 | 0.0966 | 0.0566 | 0.6743 | 0.8371 | 0.0069 | 0.0079 | 0.0023 | 0.0237 | 0.0230 | 0.0211 | 0.0746 | 0.0868 | 0.1389 | 0.2237 | 0.1929 | 0.2053 | 0.1114 | 0.0974 | 0.1389 | 0.1316 | 0.3111 | 0.2026 | 0.0017 | 0.0017 | 0.0067 | 0.0274 | 0.1016 | 0.1496 | 0.1111 | 0.1407 | 0.4595 | 58 | 75 | 93 | 117 | 144 | 179 | 227 | 297 | 404 | 0.0022 | 69.15 | 6.693 | 0.2400 | 56286.8 | 22200000 | 10500000000 | 5560000000000 | 0.5618 | 0.1030 | 0.0253 | 0.0040 | 0.1149 | 0.0127 | 0.2821 | 0.0573 | 0.1909 | 0.1131 | 0.1740 | 0.1863 | 0.1166 | 0.2126 | 0.0439 | 0.1242 | 0.0389 | 0.1449 | 0.0135 | 0.1449 | 0.0006 | 0.0019 | 0.0025 | 0.0029 | 0.0125 | 0.0058 | 0.0368 | 0.0277 | 0.1085 | 0.0893 | 0.1696 | 0.1422 | 0.1103 | 0.1053 | 0.1490 | 0.1465 | 0.4102 | 0.4784 | 0.0049 | 0.0037 | 0.0069 | 0.0075 | 0.0208 | 0.0298 | 0.0573 | 0.0658 | 0.1285 | 0.1466 | 0.1887 | 0.1814 | 0.1176 | 0.1379 | 0.1542 | 0.1466 | 0.3211 | 0.2807 | 0.0016 | 0.0071 | 0.0158 | 0.0434 | 0.1278 | 0.1838 | 0.1112 | 0.1546 | 0.3549 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1187 | 150 | | 10144 | 18089 | 422.6 | 104.34 | 134.81 | 165.74 | 292 | 329 | 360 | 387 | 413 | 441 | 470 | 509 | 564 | 0.0612 | 1107 | 0.929 | 101.98 | 22.83 | 1 | 0.0219 | 222 | 0.0007 | 49.57 | 7.512 | 0.1760 | 189470.0 | 89800000 | 44900000000 | 23500000000000 | 0.4318 | 0.2153 | 0.0002 | 0.0000 | 0.0024 | 0.0001 | 0.0055 | 0.0009 | 0.0213 | 0.0034 | 0.0707 | 0.0216 | 0.1408 | 0.0424 | 0.1325 | 0.0444 | 0.1711 | 0.0653 | 0.4554 | 0.8220 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0019 | 0.0004 | 0.0069 | 0.0013 | 0.0283 | 0.0125 | 0.0547 | 0.0201 | 0.0594 | 0.0179 | 0.0803 | 0.0312 | 0.7681 | 0.9165 | 0.0039 | 0.0043 | 0.0072 | 0.0130 | 0.0101 | 0.0391 | 0.0568 | 0.1014 | 0.0901 | 0.1681 | 0.1710 | 0.2087 | 0.1098 | 0.1087 | 0.1349 | 0.1406 | 0.4162 | 0.2159 | 0.0006 | 0.0029 | 0.0063 | 0.0240 | 0.0632 | 0.1112 | 0.1004 | 0.1280 | 0.5634 | 7 | 10 | 15 | 31 | 61 | 108 | 168 | 251 | 373 | 0.0482 | 25.89 | 5.272 | 0.4507 | 45643.3 | 21300000 | 12000000000 | 7760000000000 | 0.5745 | 0.1113 | 0.0713 | 0.0037 | 0.2521 | 0.0324 | 0.2954 | 0.1786 | 0.1297 | 0.1970 | 0.0926 | 0.1848 | 0.0798 | 0.1557 | 0.0420 | 0.0909 | 0.0207 | 0.0701 | 0.0164 | 0.0869 | 0.0003 | 0.0000 | 0.0006 | 0.0001 | 0.0007 | 0.0005 | 0.0145 | 0.0119 | 0.0699 | 0.0593 | 0.1238 | 0.1008 | 0.0735 | 0.0705 | 0.1173 | 0.1039 | 0.5995 | 0.6530 | 0.0002 | 0.0004 | 0.0020 | 0.0012 | 0.0034 | 0.0064 | 0.0225 | 0.0278 | 0.0856 | 0.0911 | 0.1447 | 0.1588 | 0.0900 | 0.0998 | 0.1345 | 0.1395 | 0.5171 | 0.4750 | 0.0006 | 0.0008 | 0.0028 | 0.0201 | 0.0798 | 0.1283 | 0.0907 | 0.1237 | 0.5531 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 158 | 814 | | 6792 | 9233 | 438.4 | 87.62 | 129.25 | 126.89 | 328 | 360 | 387 | 410 | 432 | 453 | 478 | 510 | 563 | 0.1039 | 959 | 1.120 | 105.12 | 29.02 | 1 | 0.0346 | 235 | 0.0009 | 45.63 | 7.284 | 0.1766 | 199847.0 | 94600000 | 46500000000 | 23600000000000 | 0.4114 | 0.2340 | 0.0002 | 0.0000 | 0.0009 | 0.0002 | 0.0029 | 0.0003 | 0.0152 | 0.0014 | 0.0530 | 0.0166 | 0.1082 | 0.0302 | 0.1148 | 0.0269 | 0.1594 | 0.0440 | 0.5454 | 0.8804 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0064 | 0.0000 | 0.0246 | 0.0109 | 0.0515 | 0.0199 | 0.0494 | 0.0108 | 0.0729 | 0.0223 | 0.7933 | 0.9361 | 0.0091 | 0.0087 | 0.0172 | 0.0435 | 0.0199 | 0.0913 | 0.0661 | 0.1174 | 0.1024 | 0.2261 | 0.1386 | 0.1174 | 0.1232 | 0.1739 | 0.1132 | 0.0870 | 0.4103 | 0.1348 | 0.0006 | 0.0025 | 0.0094 | 0.0253 | 0.0738 | 0.1200 | 0.1088 | 0.1385 | 0.5211 | 15 | 21 | 36 | 60 | 91 | 123 | 163 | 221 | 310 | 0.0144 | 22.41 | 5.893 | 0.4120 | 32805.8 | 11500000 | 4920000000 | 2420000000000 | 0.5918 | 0.1102 | 0.0326 | 0.0008 | 0.0932 | 0.0126 | 0.1546 | 0.0502 | 0.1430 | 0.0942 | 0.1492 | 0.1468 | 0.1430 | 0.1554 | 0.1072 | 0.1181 | 0.1049 | 0.1370 | 0.0723 | 0.2849 | 0.0002 | 0.0000 | 0.0012 | 0.0004 | 0.0062 | 0.0042 | 0.0208 | 0.0156 | 0.0649 | 0.0540 | 0.0900 | 0.0828 | 0.0815 | 0.0608 | 0.1083 | 0.0905 | 0.6269 | 0.6917 | 0.0017 | 0.0008 | 0.0031 | 0.0078 | 0.0133 | 0.0090 | 0.0269 | 0.0377 | 0.0941 | 0.1099 | 0.1339 | 0.1333 | 0.0896 | 0.1005 | 0.1210 | 0.1255 | 0.5164 | 0.4754 | 0.0009 | 0.0028 | 0.0079 | 0.0247 | 0.0791 | 0.1123 | 0.0879 | 0.1140 | 0.5705 | ||
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 354 | 420 | | 1298 | 8819 | 703.5 | 137.06 | 40.06 | 42.60 | 498 | 566 | 622 | 685 | 723 | 762 | 800 | 837 | 868 | 0.0693 | 611 | 0.939 | 34.21 | 8.06 | 4 | 0.0624 | 81 | 0.0013 | 60.83 | 6.801 | 0.1510 | 513652.0 | 387000000 | 299000000000 | 236000000000000 | 0.4003 | 0.2202 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0085 | 0.0008 | 0.0932 | 0.0281 | 0.1538 | 0.0532 | 0.1356 | 0.0258 | 0.1586 | 0.0446 | 0.4479 | 0.8475 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0008 | 0.0458 | 0.0281 | 0.0715 | 0.0532 | 0.0372 | 0.0258 | 0.0696 | 0.0446 | 0.7741 | 0.8475 | 0.0045 | 0.0000 | 0.0135 | 0.0000 | 0.0269 | 0.0000 | 0.0628 | 0.0000 | 0.1704 | 0.0000 | 0.1883 | 0.0000 | 0.1390 | 0.0000 | 0.1749 | 0.0000 | 0.2197 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0124 | 0.0634 | 0.1007 | 0.0703 | 0.1131 | 0.6386 | 12 | 14 | 16 | 19 | 24 | 30 | 39 | 56 | 96 | 0.0579 | 5.04 | 3.928 | 0.6486 | 3419.8 | 510086 | 108000000 | 28300000000 | 0.4195 | 0.2154 | 0.0197 | 0.0099 | 0.0599 | 0.0129 | 0.1125 | 0.0254 | 0.1289 | 0.0420 | 0.1724 | 0.0884 | 0.1634 | 0.1256 | 0.1330 | 0.1219 | 0.1371 | 0.1819 | 0.0731 | 0.3921 | 0.0057 | 0.0056 | 0.0106 | 0.0065 | 0.0157 | 0.0127 | 0.0205 | 0.0169 | 0.0410 | 0.0340 | 0.0651 | 0.0498 | 0.0576 | 0.0514 | 0.0923 | 0.0910 | 0.6916 | 0.7322 | 0.0014 | 0.0017 | 0.0062 | 0.0028 | 0.0105 | 0.0062 | 0.0253 | 0.0258 | 0.0581 | 0.0624 | 0.0781 | 0.0983 | 0.0696 | 0.0736 | 0.0948 | 0.0893 | 0.6560 | 0.6399 | 0.0019 | 0.0054 | 0.0101 | 0.0260 | 0.0490 | 0.0707 | 0.0634 | 0.1014 | 0.6720 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 121 | 590 | | 6826 | 22797 | 692.3 | 141.16 | 184.25 | 147.65 | 524 | 569 | 603 | 636 | 672 | 711 | 754 | 812 | 894 | 0.0504 | 1149 | 1.195 | 96.01 | 36.50 | 1 | 0.0355 | 242 | 0.0006 | 74.81 | 7.679 | 0.1333 | 499160.0 | 375000000 | 293000000000 | 238000000000000 | 0.4097 | 0.2333 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0033 | 0.0000 | 0.0134 | 0.0015 | 0.0541 | 0.0141 | 0.1179 | 0.0327 | 0.1221 | 0.0242 | 0.1447 | 0.0447 | 0.5439 | 0.8825 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0001 | 0.0244 | 0.0100 | 0.0560 | 0.0208 | 0.0529 | 0.0091 | 0.0796 | 0.0171 | 0.7802 | 0.9428 | 0.0000 | 0.0210 | 0.0059 | 0.0385 | 0.0245 | 0.0559 | 0.0422 | 0.0594 | 0.1114 | 0.1713 | 0.1401 | 0.1608 | 0.1241 | 0.1014 | 0.1595 | 0.1399 | 0.3924 | 0.2517 | 0.0007 | 0.0033 | 0.0052 | 0.0244 | 0.0711 | 0.1157 | 0.0949 | 0.1252 | 0.5596 | 31 | 53 | 80 | 111 | 147 | 188 | 236 | 298 | 396 | 0.0053 | 17.90 | 6.140 | 0.3553 | 55747.2 | 22400000 | 11300000000 | 7040000000000 | 0.4802 | 0.1654 | 0.0189 | 0.0009 | 0.1045 | 0.0065 | 0.1943 | 0.0481 | 0.1712 | 0.0929 | 0.1772 | 0.1570 | 0.1568 | 0.1982 | 0.0804 | 0.1530 | 0.0592 | 0.1463 | 0.0375 | 0.1971 | 0.0006 | 0.0003 | 0.0018 | 0.0010 | 0.0062 | 0.0037 | 0.0214 | 0.0144 | 0.0636 | 0.0533 | 0.1041 | 0.0946 | 0.0826 | 0.0723 | 0.1081 | 0.1001 | 0.6117 | 0.6604 | 0.0021 | 0.0022 | 0.0055 | 0.0077 | 0.0141 | 0.0176 | 0.0366 | 0.0471 | 0.0854 | 0.0843 | 0.1155 | 0.1211 | 0.0905 | 0.0961 | 0.1101 | 0.1108 | 0.5402 | 0.5131 | 0.0011 | 0.0033 | 0.0088 | 0.0271 | 0.0757 | 0.1130 | 0.0967 | 0.1074 | 0.5670 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 575 | | 6042 | 12072 | 101.1 | 29.15 | 201.53 | 223.69 | 69 | 77 | 84 | 91 | 97 | 103 | 110 | 120 | 139 | 0.0696 | 840 | 0.813 | 79.88 | 25.94 | 1 | 0.0386 | 233 | 0.0015 | 30.07 | 6.806 | 0.2198 | 11069.0 | 1320000 | 170000000 | 23900000000 | 0.4862 | 0.1865 | 0.0018 | 0.0002 | 0.0053 | 0.0006 | 0.0143 | 0.0023 | 0.0289 | 0.0069 | 0.0949 | 0.0296 | 0.1530 | 0.0590 | 0.1434 | 0.0611 | 0.1755 | 0.0846 | 0.3829 | 0.7558 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0005 | 0.0109 | 0.0028 | 0.0454 | 0.0160 | 0.0803 | 0.0329 | 0.0748 | 0.0325 | 0.1071 | 0.0463 | 0.6782 | 0.8690 | 0.0043 | 0.0000 | 0.0017 | 0.0123 | 0.0112 | 0.0334 | 0.0543 | 0.0598 | 0.1422 | 0.1652 | 0.1716 | 0.1845 | 0.1112 | 0.1037 | 0.1362 | 0.1564 | 0.3672 | 0.2847 | 0.0008 | 0.0053 | 0.0162 | 0.0442 | 0.0797 | 0.1330 | 0.1035 | 0.1300 | 0.4873 | 18 | 30 | 47 | 67 | 108 | 171 | 253 | 356 | 517 | 0.0128 | 34.28 | 6.003 | 0.4255 | 90647.1 | 57700000 | 45300000000 | 41800000000000 | 0.5238 | 0.1388 | 0.0299 | 0.0012 | 0.1106 | 0.0112 | 0.2542 | 0.0630 | 0.1719 | 0.1064 | 0.1356 | 0.1694 | 0.1203 | 0.2041 | 0.0759 | 0.1291 | 0.0581 | 0.1283 | 0.0436 | 0.1873 | 0.0002 | 0.0003 | 0.0012 | 0.0009 | 0.0024 | 0.0014 | 0.0120 | 0.0077 | 0.0503 | 0.0456 | 0.0918 | 0.0772 | 0.0637 | 0.0548 | 0.0892 | 0.0894 | 0.6892 | 0.7227 | 0.0008 | 0.0000 | 0.0005 | 0.0016 | 0.0040 | 0.0062 | 0.0171 | 0.0230 | 0.0656 | 0.0792 | 0.1207 | 0.1321 | 0.0874 | 0.0879 | 0.1189 | 0.1252 | 0.5850 | 0.5447 | 0.0005 | 0.0016 | 0.0021 | 0.0115 | 0.0607 | 0.1004 | 0.0736 | 0.1068 | 0.6429 |