High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 208 | 697 | | 4527 | 6306 | 102.3 | 37.27 | 112.28 | 143.75 | 55 | 71 | 81 | 90 | 99 | 108 | 118 | 131 | 151 | 0.0815 | 514 | 0.356 | 141.55 | 33.02 | 1 | 0.1199 | 543 | 0.0021 | 18.08 | 6.438 | 0.2850 | 11862.3 | 1530000 | 217000000 | 33600000000 | 0.4631 | 0.1918 | 0.0025 | 0.0009 | 0.0066 | 0.0006 | 0.0244 | 0.0036 | 0.0533 | 0.0097 | 0.1102 | 0.0425 | 0.1554 | 0.0857 | 0.1640 | 0.0808 | 0.1971 | 0.1227 | 0.2864 | 0.6534 | 0.0000 | 0.0005 | 0.0003 | 0.0003 | 0.0054 | 0.0021 | 0.0123 | 0.0049 | 0.0377 | 0.0210 | 0.0595 | 0.0395 | 0.0687 | 0.0333 | 0.1013 | 0.0546 | 0.7149 | 0.8438 | 0.0025 | 0.0115 | 0.0025 | 0.0263 | 0.0193 | 0.0197 | 0.0495 | 0.0609 | 0.1050 | 0.1184 | 0.1310 | 0.1760 | 0.1125 | 0.1250 | 0.1453 | 0.1612 | 0.4324 | 0.3010 | 0.0009 | 0.0033 | 0.0127 | 0.0216 | 0.0701 | 0.1040 | 0.0861 | 0.1092 | 0.5920 | 15 | 19 | 25 | 33 | 49 | 75 | 115 | 180 | 306 | 0.0287 | 20.58 | 5.086 | 0.4862 | 33266.2 | 15000000 | 8150000000 | 4970000000000 | 0.6440 | 0.0881 | 0.0377 | 0.0048 | 0.1319 | 0.0168 | 0.1852 | 0.0743 | 0.1397 | 0.1086 | 0.1570 | 0.1829 | 0.1287 | 0.1589 | 0.0958 | 0.1238 | 0.0628 | 0.1286 | 0.0612 | 0.2013 | 0.0013 | 0.0007 | 0.0027 | 0.0015 | 0.0080 | 0.0067 | 0.0212 | 0.0176 | 0.0734 | 0.0639 | 0.1008 | 0.1002 | 0.0787 | 0.0740 | 0.1084 | 0.1073 | 0.6055 | 0.6279 | 0.0018 | 0.0028 | 0.0025 | 0.0035 | 0.0135 | 0.0063 | 0.0308 | 0.0232 | 0.0776 | 0.0752 | 0.1145 | 0.1308 | 0.0844 | 0.0893 | 0.1041 | 0.1069 | 0.5708 | 0.5619 | 0.0016 | 0.0057 | 0.0109 | 0.0274 | 0.0677 | 0.1117 | 0.0858 | 0.1101 | 0.5791 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 762 | 189 | | 1376 | 10419 | 35.3 | 9.21 | 10.27 | 5.63 | 22 | 26 | 29 | 33 | 36 | 39 | 42 | 44 | 47 | 0.0696 | 725 | 0.931 | 32.02 | 6.00 | 6 | 0.0509 | 70 | 0.0514 | 0.71 | 3.174 | 0.7185 | 1329.9 | 52792.9 | 2180000 | 92900000 | 0.3888 | 0.2401 | 0.0112 | 0.0000 | 0.0224 | 0.0000 | 0.0384 | 0.0041 | 0.0480 | 0.0132 | 0.0880 | 0.0438 | 0.1296 | 0.0661 | 0.1552 | 0.0867 | 0.2224 | 0.1189 | 0.2848 | 0.6672 | 0.0038 | 0.0000 | 0.0029 | 0.0000 | 0.0105 | 0.0023 | 0.0134 | 0.0077 | 0.0335 | 0.0302 | 0.0374 | 0.0294 | 0.0412 | 0.0394 | 0.0766 | 0.0510 | 0.7807 | 0.8399 | 0.0167 | 0.0854 | 0.0143 | 0.1707 | 0.0263 | 0.1341 | 0.0430 | 0.2073 | 0.0740 | 0.1463 | 0.0883 | 0.2073 | 0.0931 | 0.0244 | 0.1551 | 0.0244 | 0.4893 | 0.0000 | 0.0027 | 0.0040 | 0.0121 | 0.0214 | 0.0429 | 0.0402 | 0.0657 | 0.0979 | 0.7131 | 5 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 15 | 0.2596 | 0.30 | 0.975 | 0.6174 | 137.1 | 3359.17 | 189453 | 16100000 | 0.5305 | 0.1486 | 0.0352 | 0.0019 | 0.0945 | 0.0122 | 0.1668 | 0.0289 | 0.2222 | 0.0571 | 0.2112 | 0.0964 | 0.1536 | 0.1503 | 0.0877 | 0.2161 | 0.0244 | 0.2552 | 0.0044 | 0.1819 | 0.0068 | 0.0000 | 0.0230 | 0.0021 | 0.0437 | 0.0082 | 0.0549 | 0.0212 | 0.0735 | 0.0449 | 0.0787 | 0.0675 | 0.1107 | 0.0939 | 0.1744 | 0.1513 | 0.4343 | 0.6109 | 0.0472 | 0.0923 | 0.0513 | 0.1077 | 0.0808 | 0.1294 | 0.1073 | 0.1464 | 0.1292 | 0.1422 | 0.1429 | 0.1316 | 0.1703 | 0.1167 | 0.1551 | 0.0716 | 0.1158 | 0.0621 | 0.0303 | 0.0432 | 0.0455 | 0.0586 | 0.0760 | 0.1103 | 0.1403 | 0.2192 | 0.2767 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1028 | 672 | | 465 | 2154 | 115.4 | 21.95 | 94.06 | 88.63 | 88 | 97 | 102 | 107 | 113 | 119 | 127 | 135 | 145 | 0.1467 | 316 | 0.423 | 90.70 | 21.40 | 1 | 0.5978 | 278 | 0.0052 | 16.34 | 5.463 | 0.2803 | 13796.9 | 1710000 | 218000000 | 28800000000 | 0.4162 | 0.2196 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0247 | 0.0022 | 0.0556 | 0.0111 | 0.1049 | 0.0509 | 0.1852 | 0.0907 | 0.1420 | 0.0575 | 0.1821 | 0.1062 | 0.3025 | 0.6814 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0273 | 0.0086 | 0.0695 | 0.0452 | 0.1042 | 0.0839 | 0.0720 | 0.0344 | 0.1117 | 0.0796 | 0.6104 | 0.7462 | 0.0000 | 0.0000 | 0.0380 | 0.1538 | 0.0380 | 0.0000 | 0.1139 | 0.1538 | 0.1519 | 0.3846 | 0.2152 | 0.0000 | 0.1392 | 0.1538 | 0.1139 | 0.1538 | 0.1899 | 0.0000 | 0.0000 | 0.0045 | 0.0179 | 0.0538 | 0.1345 | 0.1211 | 0.1211 | 0.1704 | 0.3767 | 17 | 26 | 35 | 44 | 58 | 78 | 107 | 164 | 229 | 0.0192 | 12.21 | 4.935 | 0.4816 | 16699.0 | 4090000 | 1190000000 | 384000000000 | 0.5433 | 0.1288 | 0.0185 | 0.0036 | 0.1218 | 0.0145 | 0.1808 | 0.0416 | 0.1734 | 0.1139 | 0.2251 | 0.1953 | 0.0959 | 0.1664 | 0.0812 | 0.1356 | 0.0554 | 0.1447 | 0.0480 | 0.1844 | 0.0000 | 0.0000 | 0.0056 | 0.0009 | 0.0090 | 0.0027 | 0.0124 | 0.0192 | 0.0710 | 0.0602 | 0.1150 | 0.0794 | 0.0744 | 0.0776 | 0.1488 | 0.1487 | 0.5637 | 0.6113 | 0.0016 | 0.0000 | 0.0032 | 0.0018 | 0.0065 | 0.0147 | 0.0260 | 0.0313 | 0.0666 | 0.0792 | 0.1380 | 0.1455 | 0.0893 | 0.0958 | 0.1347 | 0.1602 | 0.5341 | 0.4715 | 0.0014 | 0.0082 | 0.0109 | 0.0301 | 0.0657 | 0.1012 | 0.0821 | 0.1477 | 0.5527 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 954 | 880 | | 1679 | 5441 | 653.6 | 119.11 | 75.62 | 146.47 | 478 | 542 | 591 | 627 | 661 | 696 | 731 | 766 | 800 | 0.0884 | 481 | 0.755 | 132.23 | 36.35 | 1 | 0.2287 | 384 | 0.0009 | 82.04 | 7.094 | 0.1478 | 441315.0 | 307000000 | 218000000000 | 159000000000000 | 0.3946 | 0.2342 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0086 | 0.0018 | 0.0522 | 0.0283 | 0.0779 | 0.0361 | 0.0693 | 0.0307 | 0.1259 | 0.0451 | 0.6652 | 0.8581 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0018 | 0.0313 | 0.0281 | 0.0392 | 0.0329 | 0.0271 | 0.0257 | 0.0499 | 0.0418 | 0.8504 | 0.8698 | 0.0042 | 0.0000 | 0.0169 | 0.0000 | 0.0254 | 0.0000 | 0.0424 | 0.0000 | 0.0890 | 0.0000 | 0.1271 | 0.0000 | 0.1144 | 0.0000 | 0.1271 | 0.0000 | 0.4534 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0103 | 0.0525 | 0.0627 | 0.0490 | 0.0855 | 0.7343 | 7 | 9 | 11 | 13 | 17 | 28 | 60 | 104 | 173 | 0.0733 | 1.76 | 2.761 | 0.5531 | 27168.4 | 17800000 | 14800000000 | 13800000000000 | 0.4065 | 0.2202 | 0.0128 | 0.0026 | 0.0204 | 0.0102 | 0.0510 | 0.0269 | 0.1301 | 0.0409 | 0.1913 | 0.0882 | 0.2041 | 0.1317 | 0.1735 | 0.1228 | 0.1301 | 0.2008 | 0.0867 | 0.3760 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0018 | 0.0027 | 0.0092 | 0.0070 | 0.0308 | 0.0271 | 0.0450 | 0.0411 | 0.0431 | 0.0319 | 0.0603 | 0.0541 | 0.8097 | 0.8343 | 0.0008 | 0.0009 | 0.0000 | 0.0019 | 0.0049 | 0.0075 | 0.0130 | 0.0160 | 0.0381 | 0.0479 | 0.0657 | 0.0695 | 0.0536 | 0.0638 | 0.0869 | 0.0892 | 0.7370 | 0.7033 | 0.0000 | 0.0063 | 0.0042 | 0.0105 | 0.0359 | 0.0450 | 0.0549 | 0.0703 | 0.7729 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1074 | 329 | | 10716 | 23313 | 347.7 | 91.75 | 73.56 | 114.94 | 242 | 269 | 292 | 314 | 335 | 358 | 384 | 417 | 474 | 0.0592 | 1380 | 0.979 | 123.69 | 46.10 | 1 | 0.0314 | 336 | 0.0009 | 44.10 | 7.309 | 0.1906 | 129299.0 | 51400000 | 21900000000 | 9900000000000 | 0.4246 | 0.2290 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0081 | 0.0003 | 0.0209 | 0.0023 | 0.0739 | 0.0236 | 0.1547 | 0.0469 | 0.1487 | 0.0470 | 0.1829 | 0.0798 | 0.4092 | 0.8000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0001 | 0.0067 | 0.0011 | 0.0320 | 0.0128 | 0.0693 | 0.0240 | 0.0655 | 0.0222 | 0.0943 | 0.0426 | 0.7287 | 0.8973 | 0.0038 | 0.0033 | 0.0108 | 0.0043 | 0.0169 | 0.0174 | 0.0606 | 0.0587 | 0.0983 | 0.1293 | 0.1396 | 0.1772 | 0.0973 | 0.1283 | 0.1189 | 0.1533 | 0.4537 | 0.3283 | 0.0011 | 0.0027 | 0.0078 | 0.0287 | 0.0782 | 0.1249 | 0.0938 | 0.1276 | 0.5352 | 5 | 6 | 8 | 9 | 13 | 34 | 72 | 133 | 226 | 0.0834 | 10.03 | 3.982 | 0.5196 | 18622.6 | 7300000 | 3800000000 | 2450000000000 | 0.4789 | 0.1814 | 0.0998 | 0.0031 | 0.2338 | 0.0435 | 0.2680 | 0.1682 | 0.1369 | 0.1634 | 0.1119 | 0.1864 | 0.0720 | 0.1590 | 0.0371 | 0.0956 | 0.0306 | 0.0815 | 0.0100 | 0.0993 | 0.0004 | 0.0001 | 0.0003 | 0.0006 | 0.0013 | 0.0018 | 0.0095 | 0.0100 | 0.0610 | 0.0508 | 0.0917 | 0.0745 | 0.0604 | 0.0548 | 0.1046 | 0.0852 | 0.6708 | 0.7222 | 0.0002 | 0.0004 | 0.0018 | 0.0009 | 0.0024 | 0.0034 | 0.0180 | 0.0181 | 0.0720 | 0.0856 | 0.1220 | 0.1315 | 0.0802 | 0.0846 | 0.1175 | 0.1264 | 0.5860 | 0.5492 | 0.0001 | 0.0003 | 0.0026 | 0.0135 | 0.0658 | 0.1063 | 0.0699 | 0.1141 | 0.6274 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 382 | 919 | | 6897 | 11121 | 362.8 | 74.41 | 225.10 | 252.79 | 267 | 298 | 321 | 341 | 358 | 379 | 401 | 427 | 462 | 0.0739 | 822 | 1.086 | 120.93 | 34.41 | 1 | 0.0406 | 280 | 0.0009 | 36.87 | 7.251 | 0.1983 | 137149.0 | 53900000 | 21900000000 | 9220000000000 | 0.4314 | 0.2131 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0005 | 0.0135 | 0.0012 | 0.0506 | 0.0134 | 0.0981 | 0.0302 | 0.1155 | 0.0258 | 0.1361 | 0.0368 | 0.5832 | 0.8921 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0002 | 0.0004 | 0.0061 | 0.0010 | 0.0215 | 0.0104 | 0.0426 | 0.0219 | 0.0481 | 0.0148 | 0.0570 | 0.0214 | 0.8240 | 0.9300 | 0.0050 | 0.0000 | 0.0075 | 0.0000 | 0.0199 | 0.0000 | 0.0489 | 0.0000 | 0.1095 | 0.0000 | 0.1376 | 0.0000 | 0.1086 | 0.0000 | 0.1327 | 0.0000 | 0.4303 | 0.0000 | 0.0003 | 0.0024 | 0.0055 | 0.0240 | 0.0518 | 0.1046 | 0.0888 | 0.1001 | 0.6225 | 16 | 19 | 26 | 60 | 133 | 209 | 292 | 408 | 608 | 0.0252 | 45.18 | 5.945 | 0.4029 | 114568.0 | 77900000 | 62700000000 | 56900000000000 | 0.5295 | 0.1405 | 0.0233 | 0.0008 | 0.1395 | 0.0101 | 0.2197 | 0.0563 | 0.1828 | 0.1049 | 0.1612 | 0.1734 | 0.1275 | 0.1937 | 0.0762 | 0.1418 | 0.0489 | 0.1329 | 0.0209 | 0.1860 | 0.0004 | 0.0002 | 0.0004 | 0.0004 | 0.0021 | 0.0016 | 0.0092 | 0.0085 | 0.0536 | 0.0397 | 0.0929 | 0.0707 | 0.0709 | 0.0541 | 0.1009 | 0.0724 | 0.6695 | 0.7524 | 0.0003 | 0.0010 | 0.0008 | 0.0029 | 0.0058 | 0.0059 | 0.0202 | 0.0280 | 0.0810 | 0.0982 | 0.1221 | 0.1321 | 0.0928 | 0.0956 | 0.1260 | 0.1337 | 0.5510 | 0.5026 | 0.0000 | 0.0010 | 0.0036 | 0.0157 | 0.0703 | 0.1098 | 0.0834 | 0.1150 | 0.6013 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 462 | 109 | | 459 | 1169 | 64.3 | 13.23 | 8.02 | 2.47 | 48 | 52 | 57 | 61 | 64 | 67 | 71 | 74 | 79 | 0.2515 | 294 | 0.892 | 64.33 | 20.81 | 1 | 0.3791 | 174 | 0.0526 | 1.06 | 3.212 | 0.6390 | 4308.5 | 301320 | 22000000 | 1690000000 | 0.4020 | 0.2263 | 0.0000 | 0.0000 | 0.0063 | 0.0023 | 0.0094 | 0.0068 | 0.0408 | 0.0068 | 0.0940 | 0.0502 | 0.1160 | 0.1073 | 0.1473 | 0.0662 | 0.2508 | 0.0936 | 0.3354 | 0.6667 | 0.0000 | 0.0000 | 0.0026 | 0.0022 | 0.0026 | 0.0066 | 0.0238 | 0.0044 | 0.0556 | 0.0462 | 0.0635 | 0.0879 | 0.0714 | 0.0505 | 0.1111 | 0.0725 | 0.6693 | 0.7297 | 0.0678 | 0.0000 | 0.0508 | 0.0000 | 0.1356 | 0.0588 | 0.0339 | 0.1176 | 0.2034 | 0.2941 | 0.1186 | 0.1176 | 0.0678 | 0.1176 | 0.1356 | 0.2353 | 0.1864 | 0.0588 | 0.0041 | 0.0041 | 0.0245 | 0.0245 | 0.0735 | 0.0939 | 0.0898 | 0.1796 | 0.5061 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0200 | 12.70 | 4.330 | 0.3019 | 70.5 | 664.57 | 6651.59 | 70129.1 | 0.5248 | 0.1240 | 0.0136 | 0.0000 | 0.0492 | 0.0010 | 0.1121 | 0.0149 | 0.2462 | 0.0378 | 0.2394 | 0.0746 | 0.2190 | 0.1303 | 0.1002 | 0.2139 | 0.0187 | 0.2806 | 0.0017 | 0.2468 | 0.0000 | 0.0000 | 0.0099 | 0.0009 | 0.0221 | 0.0027 | 0.0585 | 0.0220 | 0.1170 | 0.0577 | 0.2064 | 0.0843 | 0.2274 | 0.1357 | 0.2506 | 0.2878 | 0.1082 | 0.4088 | 0.1199 | 0.5814 | 0.2461 | 0.2907 | 0.2366 | 0.0814 | 0.1924 | 0.0349 | 0.1293 | 0.0116 | 0.0536 | 0.0000 | 0.0158 | 0.0000 | 0.0032 | 0.0000 | 0.0032 | 0.0000 | 0.0126 | 0.0535 | 0.1258 | 0.2013 | 0.2186 | 0.1714 | 0.1336 | 0.0708 | 0.0126 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 550 | 588 | | 3961 | 12702 | 362.6 | 74.74 | 145.47 | 313.98 | 267 | 301 | 325 | 344 | 362 | 380 | 400 | 423 | 452 | 0.0624 | 793 | 1.103 | 133.51 | 42.58 | 1 | 0.0836 | 331 | 0.0009 | 60.00 | 7.202 | 0.1727 | 137032.0 | 53800000 | 22000000000 | 9300000000000 | 0.4189 | 0.2240 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0191 | 0.0008 | 0.0484 | 0.0174 | 0.0949 | 0.0441 | 0.1019 | 0.0284 | 0.1484 | 0.0412 | 0.5837 | 0.8681 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0008 | 0.0179 | 0.0148 | 0.0363 | 0.0309 | 0.0312 | 0.0140 | 0.0515 | 0.0197 | 0.8556 | 0.9198 | 0.0035 | 0.0177 | 0.0209 | 0.0088 | 0.0435 | 0.0796 | 0.1009 | 0.1504 | 0.1687 | 0.1770 | 0.1965 | 0.2566 | 0.1287 | 0.0442 | 0.1270 | 0.1150 | 0.2104 | 0.1504 | 0.0015 | 0.0025 | 0.0066 | 0.0207 | 0.0673 | 0.1037 | 0.0967 | 0.1463 | 0.5547 | 8 | 11 | 14 | 21 | 33 | 53 | 90 | 169 | 374 | 0.0996 | 33.81 | 4.438 | 0.6074 | 119740.0 | 178000000 | 330000000000 | 679000000000000 | 0.4919 | 0.1485 | 0.0193 | 0.0012 | 0.1035 | 0.0094 | 0.2190 | 0.0528 | 0.2154 | 0.0944 | 0.2106 | 0.1812 | 0.1408 | 0.2223 | 0.0590 | 0.1554 | 0.0217 | 0.1384 | 0.0108 | 0.1449 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0018 | 0.0021 | 0.0121 | 0.0100 | 0.0667 | 0.0554 | 0.1113 | 0.0915 | 0.0640 | 0.0610 | 0.0969 | 0.0879 | 0.6473 | 0.6909 | 0.0000 | 0.0005 | 0.0024 | 0.0064 | 0.0064 | 0.0055 | 0.0189 | 0.0132 | 0.0781 | 0.0783 | 0.1305 | 0.1429 | 0.0673 | 0.0660 | 0.0995 | 0.1051 | 0.5969 | 0.5822 | 0.0003 | 0.0007 | 0.0031 | 0.0146 | 0.0809 | 0.1122 | 0.0729 | 0.0983 | 0.6170 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 321 | 840 | | 426 | 368 | 95.5 | 47.70 | 697.86 | 488.70 | 32 | 42 | 60 | 77 | 96 | 112 | 127 | 143 | 162 | 0.4701 | 173 | 0.664 | 93.61 | 19.80 | 1 | 0.5915 | 252 | 0.0030 | 67.57 | 5.878 | 0.1356 | 11384.7 | 1540000 | 222000000 | 33700000000 | 0.2891 | 0.3236 | 0.0000 | 0.0000 | 0.0000 | 0.0052 | 0.1616 | 0.0000 | 0.1919 | 0.0155 | 0.2121 | 0.1503 | 0.1515 | 0.2591 | 0.2020 | 0.1295 | 0.0404 | 0.1969 | 0.0404 | 0.2435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0032 | 0.0575 | 0.0583 | 0.0996 | 0.0841 | 0.0421 | 0.0388 | 0.0613 | 0.0680 | 0.7318 | 0.7476 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0247 | 0.0517 | 0.0802 | 0.0862 | 0.1049 | 0.1897 | 0.0988 | 0.1207 | 0.1420 | 0.1034 | 0.5432 | 0.4483 | 0.0000 | 0.0000 | 0.0000 | 0.0140 | 0.0698 | 0.0930 | 0.0512 | 0.0884 | 0.6837 | 135 | 270 | 399 | 510 | 616 | 717 | 852 | 1036 | 1456 | 0.0038 | 170.10 | 5.726 | 0.1849 | 725176.0 | 955000000 | 1470000000000 | 2.5E+15 | 0.4289 | 0.2015 | 0.0465 | 0.0000 | 0.1860 | 0.0120 | 0.2558 | 0.0663 | 0.1279 | 0.1205 | 0.1047 | 0.2651 | 0.1395 | 0.2108 | 0.0814 | 0.1566 | 0.0581 | 0.0904 | 0.0000 | 0.0783 | 0.0050 | 0.0000 | 0.0300 | 0.0000 | 0.0550 | 0.0405 | 0.0750 | 0.0526 | 0.1250 | 0.1579 | 0.1600 | 0.1741 | 0.1700 | 0.1660 | 0.1450 | 0.1296 | 0.2350 | 0.2794 | 0.0439 | 0.0000 | 0.0351 | 0.0000 | 0.0263 | 0.0864 | 0.1228 | 0.0864 | 0.1053 | 0.1605 | 0.2193 | 0.1235 | 0.0965 | 0.1111 | 0.0965 | 0.1358 | 0.2544 | 0.2963 | 0.0132 | 0.0395 | 0.0724 | 0.0921 | 0.1645 | 0.1579 | 0.1382 | 0.0921 | 0.2303 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1038 | 275 | | 2549 | 7083 | 109.6 | 30.68 | 184.05 | 241.54 | 75 | 84 | 91 | 98 | 105 | 112 | 121 | 136 | 154 | 0.0947 | 671 | 1.027 | 25.30 | 7.21 | 3 | 0.0259 | 66 | 0.0014 | 42.86 | 6.822 | 0.1813 | 12951.7 | 1640000 | 223000000 | 32000000000 | 0.4118 | 0.2282 | 0.0015 | 0.0000 | 0.0022 | 0.0005 | 0.0133 | 0.0014 | 0.0517 | 0.0115 | 0.1123 | 0.0460 | 0.1477 | 0.0815 | 0.1388 | 0.0847 | 0.1736 | 0.1119 | 0.3589 | 0.6625 | 0.0010 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0000 | 0.0172 | 0.0078 | 0.0406 | 0.0271 | 0.0630 | 0.0427 | 0.0734 | 0.0447 | 0.0963 | 0.0554 | 0.7033 | 0.8223 | 0.0035 | 0.0038 | 0.0071 | 0.0038 | 0.0088 | 0.0530 | 0.0511 | 0.0758 | 0.0935 | 0.1818 | 0.1587 | 0.2121 | 0.1481 | 0.1326 | 0.1393 | 0.1477 | 0.3898 | 0.1894 | 0.0018 | 0.0083 | 0.0110 | 0.0486 | 0.0734 | 0.1174 | 0.1119 | 0.1321 | 0.4954 | 18 | 22 | 27 | 38 | 68 | 125 | 209 | 326 | 518 | 0.0589 | 18.80 | 4.871 | 0.5443 | 92206.1 | 68200000 | 62400000000 | 65700000000000 | 0.6387 | 0.0776 | 0.0420 | 0.0017 | 0.1714 | 0.0247 | 0.2454 | 0.0945 | 0.1765 | 0.1218 | 0.1513 | 0.1891 | 0.1143 | 0.2121 | 0.0588 | 0.1175 | 0.0303 | 0.1039 | 0.0101 | 0.1346 | 0.0008 | 0.0003 | 0.0004 | 0.0020 | 0.0030 | 0.0020 | 0.0114 | 0.0095 | 0.0568 | 0.0446 | 0.0936 | 0.0936 | 0.0720 | 0.0554 | 0.1258 | 0.1065 | 0.6364 | 0.6860 | 0.0010 | 0.0011 | 0.0020 | 0.0028 | 0.0064 | 0.0073 | 0.0210 | 0.0196 | 0.0787 | 0.0896 | 0.1232 | 0.1328 | 0.0914 | 0.0980 | 0.1355 | 0.1434 | 0.5408 | 0.5053 | 0.0000 | 0.0013 | 0.0022 | 0.0176 | 0.0693 | 0.1015 | 0.0942 | 0.1321 | 0.5818 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 100 | 607 | | 540 | 5580 | 379.2 | 43.12 | 73.69 | 167.23 | 318 | 337 | 353 | 372 | 384 | 393 | 405 | 418 | 436 | 0.0710 | 396 | 0.750 | 109.88 | 35.01 | 2 | 0.6222 | 336 | 0.0034 | 25.50 | 5.823 | 0.2191 | 145633.0 | 56600000 | 22300000000 | 8850000000000 | 0.3869 | 0.2443 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0080 | 0.0019 | 0.0459 | 0.0426 | 0.0719 | 0.0630 | 0.0599 | 0.0315 | 0.0719 | 0.0537 | 0.7405 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0039 | 0.0019 | 0.0426 | 0.0426 | 0.0638 | 0.0630 | 0.0329 | 0.0315 | 0.0561 | 0.0537 | 0.7988 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0625 | 0.0000 | 0.1250 | 0.0000 | 0.4375 | 0.0000 | 0.0625 | 0.0000 | 0.2500 | 0.0000 | 0.0625 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0241 | 0.0552 | 0.0897 | 0.0828 | 0.1276 | 0.6138 | 10 | 13 | 15 | 17 | 20 | 25 | 42 | 99 | 162 | 0.2249 | 3.67 | 2.655 | 0.7483 | 33390.0 | 36400000 | 52700000000 | 84800000000000 | 0.5879 | 0.1256 | 0.0385 | 0.0052 | 0.0427 | 0.0174 | 0.1026 | 0.0261 | 0.1880 | 0.0540 | 0.2222 | 0.1237 | 0.1624 | 0.1429 | 0.1496 | 0.1655 | 0.0684 | 0.2003 | 0.0256 | 0.2648 | 0.0007 | 0.0018 | 0.0014 | 0.0043 | 0.0027 | 0.0037 | 0.0075 | 0.0043 | 0.0177 | 0.0178 | 0.0198 | 0.0227 | 0.0355 | 0.0233 | 0.0539 | 0.0491 | 0.8608 | 0.8729 | 0.0000 | 0.0038 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0154 | 0.0227 | 0.0292 | 0.0360 | 0.0382 | 0.0588 | 0.0544 | 0.0682 | 0.1072 | 0.0986 | 0.7555 | 0.7024 | 0.0007 | 0.0007 | 0.0029 | 0.0059 | 0.0192 | 0.0354 | 0.0347 | 0.0560 | 0.8444 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1021 | 289 | | 15480 | 20962 | 107.9 | 32.54 | 126.87 | 115.24 | 70 | 80 | 88 | 96 | 104 | 112 | 122 | 133 | 151 | 0.0665 | 1394 | 1.246 | 41.87 | 18.36 | 4 | 0.0075 | 116 | 0.0011 | 32.98 | 7.115 | 0.2122 | 12708.7 | 1630000 | 225000000 | 33600000000 | 0.4430 | 0.2071 | 0.0021 | 0.0002 | 0.0042 | 0.0005 | 0.0146 | 0.0012 | 0.0424 | 0.0071 | 0.1092 | 0.0273 | 0.1709 | 0.0639 | 0.1595 | 0.0673 | 0.1788 | 0.1076 | 0.3183 | 0.7248 | 0.0014 | 0.0002 | 0.0020 | 0.0003 | 0.0039 | 0.0009 | 0.0118 | 0.0037 | 0.0393 | 0.0149 | 0.0650 | 0.0333 | 0.0601 | 0.0290 | 0.0876 | 0.0504 | 0.7289 | 0.8672 | 0.0025 | 0.0080 | 0.0037 | 0.0173 | 0.0202 | 0.0306 | 0.0567 | 0.0766 | 0.1110 | 0.1671 | 0.1514 | 0.1598 | 0.1194 | 0.1152 | 0.1455 | 0.1418 | 0.3896 | 0.2836 | 0.0011 | 0.0021 | 0.0090 | 0.0274 | 0.0627 | 0.1065 | 0.0944 | 0.1225 | 0.5742 | 16 | 27 | 45 | 67 | 94 | 124 | 161 | 212 | 289 | 0.0159 | 8.96 | 5.332 | 0.5036 | 29376.6 | 9390000 | 3750000000 | 1790000000000 | 0.4948 | 0.1572 | 0.0112 | 0.0016 | 0.0613 | 0.0068 | 0.1433 | 0.0245 | 0.1682 | 0.0618 | 0.1919 | 0.1370 | 0.1645 | 0.1771 | 0.1051 | 0.1416 | 0.0836 | 0.1568 | 0.0709 | 0.2928 | 0.0008 | 0.0004 | 0.0011 | 0.0016 | 0.0035 | 0.0026 | 0.0133 | 0.0076 | 0.0489 | 0.0371 | 0.0788 | 0.0577 | 0.0640 | 0.0520 | 0.0930 | 0.0767 | 0.6966 | 0.7643 | 0.0006 | 0.0013 | 0.0028 | 0.0020 | 0.0070 | 0.0071 | 0.0249 | 0.0329 | 0.0705 | 0.0821 | 0.1139 | 0.1305 | 0.0891 | 0.1028 | 0.1163 | 0.1349 | 0.5748 | 0.5065 | 0.0001 | 0.0018 | 0.0055 | 0.0186 | 0.0602 | 0.0898 | 0.0819 | 0.1099 | 0.6321 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1037 | 548 | | 6893 | 19634 | 196.4 | 53.42 | 59.21 | 59.92 | 132 | 150 | 164 | 177 | 190 | 203 | 219 | 239 | 270 | 0.0562 | 1104 | 1.139 | 106.17 | 38.83 | 1 | 0.0396 | 273 | 0.0009 | 48.97 | 7.272 | 0.1760 | 41433.9 | 9350000 | 2250000000 | 573000000000 | 0.4801 | 0.1819 | 0.0008 | 0.0000 | 0.0027 | 0.0003 | 0.0176 | 0.0008 | 0.0295 | 0.0045 | 0.1140 | 0.0308 | 0.1710 | 0.0578 | 0.1497 | 0.0610 | 0.1702 | 0.0896 | 0.3445 | 0.7552 | 0.0004 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0002 | 0.0060 | 0.0012 | 0.0441 | 0.0158 | 0.0768 | 0.0292 | 0.0676 | 0.0257 | 0.1060 | 0.0467 | 0.6977 | 0.8812 | 0.0027 | 0.0063 | 0.0033 | 0.0110 | 0.0154 | 0.0267 | 0.0642 | 0.0879 | 0.1338 | 0.1586 | 0.1893 | 0.2198 | 0.1097 | 0.1224 | 0.1431 | 0.1429 | 0.3385 | 0.2245 | 0.0019 | 0.0013 | 0.0079 | 0.0282 | 0.0904 | 0.1431 | 0.1028 | 0.1352 | 0.4891 | 11 | 20 | 27 | 36 | 45 | 56 | 68 | 85 | 113 | 0.0115 | 9.46 | 5.188 | 0.4764 | 7095.4 | 1710000 | 681000000 | 349000000000 | 0.5533 | 0.1205 | 0.0095 | 0.0030 | 0.0478 | 0.0089 | 0.1372 | 0.0199 | 0.1794 | 0.0504 | 0.1937 | 0.1192 | 0.1744 | 0.1608 | 0.1277 | 0.1622 | 0.0842 | 0.1835 | 0.0462 | 0.2921 | 0.0014 | 0.0014 | 0.0025 | 0.0030 | 0.0103 | 0.0063 | 0.0254 | 0.0159 | 0.0611 | 0.0437 | 0.0923 | 0.0664 | 0.0846 | 0.0698 | 0.1181 | 0.1017 | 0.6043 | 0.6918 | 0.0040 | 0.0052 | 0.0059 | 0.0136 | 0.0158 | 0.0236 | 0.0370 | 0.0536 | 0.0902 | 0.0983 | 0.1230 | 0.1323 | 0.1097 | 0.1162 | 0.1320 | 0.1328 | 0.4824 | 0.4244 | 0.0026 | 0.0071 | 0.0163 | 0.0301 | 0.0751 | 0.0993 | 0.0984 | 0.1252 | 0.5459 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 634 | 828 | | 6200 | 7303 | 203.7 | 43.18 | 209.83 | 149.65 | 154 | 167 | 178 | 188 | 198 | 208 | 221 | 237 | 262 | 0.1191 | 870 | 1.113 | 92.59 | 26.68 | 1 | 0.0353 | 219 | 0.0012 | 41.78 | 7.014 | 0.1838 | 43340.5 | 9650000 | 2250000000 | 547000000000 | 0.4334 | 0.2122 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0003 | 0.0157 | 0.0007 | 0.0711 | 0.0174 | 0.1256 | 0.0376 | 0.1517 | 0.0398 | 0.1830 | 0.0615 | 0.4490 | 0.8428 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0066 | 0.0000 | 0.0335 | 0.0122 | 0.0534 | 0.0229 | 0.0720 | 0.0143 | 0.0964 | 0.0265 | 0.7359 | 0.9239 | 0.0059 | 0.0102 | 0.0088 | 0.0307 | 0.0137 | 0.0648 | 0.0715 | 0.1160 | 0.1538 | 0.1945 | 0.1851 | 0.1672 | 0.1303 | 0.1297 | 0.1538 | 0.1229 | 0.2772 | 0.1638 | 0.0025 | 0.0040 | 0.0087 | 0.0395 | 0.0938 | 0.1242 | 0.1177 | 0.1409 | 0.4687 | 40 | 70 | 103 | 137 | 177 | 225 | 280 | 343 | 426 | 0.0014 | 93.66 | 7.304 | 0.1920 | 66420.4 | 25900000 | 11500000000 | 5580000000000 | 0.5796 | 0.1202 | 0.0390 | 0.0023 | 0.1851 | 0.0148 | 0.2695 | 0.0760 | 0.1802 | 0.1442 | 0.1420 | 0.1832 | 0.1063 | 0.2186 | 0.0446 | 0.1454 | 0.0219 | 0.1134 | 0.0114 | 0.1021 | 0.0005 | 0.0007 | 0.0029 | 0.0009 | 0.0084 | 0.0050 | 0.0260 | 0.0176 | 0.0825 | 0.0686 | 0.1372 | 0.1114 | 0.1075 | 0.0997 | 0.1319 | 0.1233 | 0.5030 | 0.5729 | 0.0019 | 0.0034 | 0.0051 | 0.0059 | 0.0179 | 0.0206 | 0.0451 | 0.0677 | 0.1147 | 0.1290 | 0.1683 | 0.1986 | 0.1306 | 0.1226 | 0.1446 | 0.1466 | 0.3719 | 0.3055 | 0.0003 | 0.0064 | 0.0121 | 0.0359 | 0.0978 | 0.1547 | 0.1134 | 0.1556 | 0.4239 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 176 | 439 | | 2149 | 10252 | 192.6 | 59.91 | 8.87 | 3.44 | 120 | 133 | 148 | 165 | 184 | 205 | 228 | 254 | 283 | 0.0694 | 712 | 0.822 | 57.98 | 20.03 | 1 | 0.0814 | 175 | 0.0084 | 2.12 | 4.986 | 0.5414 | 40700.9 | 9310000 | 2270000000 | 578000000000 | 0.3740 | 0.2645 | 0.0013 | 0.0012 | 0.0076 | 0.0030 | 0.0076 | 0.0041 | 0.0278 | 0.0100 | 0.0682 | 0.0349 | 0.1174 | 0.0573 | 0.1023 | 0.0473 | 0.1452 | 0.0810 | 0.5227 | 0.7612 | 0.0000 | 0.0010 | 0.0043 | 0.0020 | 0.0021 | 0.0030 | 0.0100 | 0.0070 | 0.0242 | 0.0214 | 0.0356 | 0.0349 | 0.0342 | 0.0244 | 0.0456 | 0.0449 | 0.8439 | 0.8614 | 0.0000 | 0.0064 | 0.0000 | 0.0032 | 0.0065 | 0.0127 | 0.0196 | 0.0255 | 0.0344 | 0.0541 | 0.0687 | 0.0637 | 0.0507 | 0.0732 | 0.0589 | 0.0669 | 0.7610 | 0.6943 | 0.0000 | 0.0000 | 0.0072 | 0.0196 | 0.0319 | 0.0330 | 0.0484 | 0.0649 | 0.7951 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 0.0123 | 12.27 | 4.870 | 0.3144 | 90.5 | 1065.26 | 14510.9 | 227463 | 0.4586 | 0.1831 | 0.0295 | 0.0009 | 0.1028 | 0.0024 | 0.1962 | 0.0094 | 0.2565 | 0.0319 | 0.2244 | 0.0719 | 0.1268 | 0.1660 | 0.0511 | 0.2677 | 0.0112 | 0.2954 | 0.0016 | 0.1543 | 0.0050 | 0.0000 | 0.0247 | 0.0004 | 0.0691 | 0.0026 | 0.1247 | 0.0146 | 0.1520 | 0.0414 | 0.1628 | 0.1000 | 0.1487 | 0.1803 | 0.1348 | 0.2780 | 0.1782 | 0.3828 | 0.1256 | 0.1981 | 0.1426 | 0.1338 | 0.1343 | 0.1060 | 0.1181 | 0.0730 | 0.1121 | 0.0782 | 0.0895 | 0.0773 | 0.0642 | 0.0695 | 0.0701 | 0.0712 | 0.1434 | 0.1929 | 0.0242 | 0.0702 | 0.1099 | 0.1423 | 0.1381 | 0.1306 | 0.1204 | 0.1069 | 0.1574 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 592 | 492 | | 4236 | 12697 | 651.9 | 140.09 | 147.12 | 254.46 | 443 | 556 | 603 | 639 | 676 | 704 | 732 | 763 | 805 | 0.0784 | 995 | 1.202 | 120.07 | 45.18 | 3 | 0.0708 | 300 | 0.0015 | 22.93 | 6.808 | 0.2599 | 444572.0 | 313000000 | 227000000000 | 168000000000000 | 0.4044 | 0.2398 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0034 | 0.0003 | 0.0058 | 0.0021 | 0.0378 | 0.0206 | 0.0903 | 0.0398 | 0.0701 | 0.0247 | 0.1192 | 0.0367 | 0.6731 | 0.8759 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0003 | 0.0006 | 0.0013 | 0.0152 | 0.0187 | 0.0336 | 0.0329 | 0.0175 | 0.0152 | 0.0336 | 0.0255 | 0.8987 | 0.9062 | 0.0079 | 0.0000 | 0.0111 | 0.0154 | 0.0300 | 0.1385 | 0.0679 | 0.1385 | 0.1153 | 0.2308 | 0.1801 | 0.1846 | 0.1153 | 0.1385 | 0.1485 | 0.1231 | 0.3239 | 0.0308 | 0.0000 | 0.0017 | 0.0033 | 0.0079 | 0.0426 | 0.0857 | 0.0662 | 0.0919 | 0.7007 | 8 | 9 | 11 | 14 | 20 | 38 | 105 | 241 | 506 | 0.1619 | 33.70 | 4.314 | 0.6111 | 86390.9 | 71500000 | 69700000000 | 75500000000000 | 0.6018 | 0.0757 | 0.0644 | 0.0043 | 0.2356 | 0.0325 | 0.2932 | 0.1702 | 0.1458 | 0.1856 | 0.1136 | 0.2002 | 0.0661 | 0.1856 | 0.0373 | 0.0821 | 0.0305 | 0.0736 | 0.0136 | 0.0659 | 0.0000 | 0.0003 | 0.0014 | 0.0000 | 0.0005 | 0.0025 | 0.0096 | 0.0093 | 0.0536 | 0.0496 | 0.1026 | 0.0981 | 0.0517 | 0.0496 | 0.0780 | 0.0733 | 0.7027 | 0.7174 | 0.0003 | 0.0007 | 0.0013 | 0.0004 | 0.0023 | 0.0011 | 0.0134 | 0.0173 | 0.0623 | 0.0665 | 0.1086 | 0.1122 | 0.0633 | 0.0725 | 0.0939 | 0.0952 | 0.6546 | 0.6341 | 0.0000 | 0.0012 | 0.0024 | 0.0150 | 0.0559 | 0.1057 | 0.0574 | 0.0811 | 0.6813 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 181 | 254 | | 1614 | 11324 | 1117.5 | 296.73 | 9.91 | 3.01 | 735 | 828 | 914 | 1000 | 1089 | 1176 | 1265 | 1423 | 1565 | 0.0770 | 872 | 1.072 | 79.08 | 22.56 | 2 | 0.1121 | 181 | 0.0011 | 52.02 | 6.977 | 0.1957 | 1340000.0 | 1700000000 | 2270000000000 | 3.16E+15 | 0.3925 | 0.2330 | 0.0013 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0043 | 0.0090 | 0.0078 | 0.0859 | 0.0456 | 0.1538 | 0.0820 | 0.1013 | 0.0520 | 0.1115 | 0.0834 | 0.5372 | 0.7242 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0043 | 0.0058 | 0.0445 | 0.0358 | 0.0676 | 0.0588 | 0.0360 | 0.0371 | 0.0668 | 0.0543 | 0.7800 | 0.8056 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0124 | 0.0103 | 0.0248 | 0.0490 | 0.0745 | 0.0979 | 0.1242 | 0.0515 | 0.0745 | 0.0670 | 0.1304 | 0.7242 | 0.5528 | 0.0000 | 0.0000 | 0.0013 | 0.0066 | 0.0584 | 0.0717 | 0.0491 | 0.0704 | 0.7424 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 12 | 14 | 0.4427 | 0.33 | 0.894 | 0.7893 | 107.3 | 1247.66 | 15428.7 | 201459 | 0.5329 | 0.1343 | 0.0090 | 0.0001 | 0.0432 | 0.0015 | 0.1219 | 0.0064 | 0.2092 | 0.0237 | 0.2630 | 0.0647 | 0.2046 | 0.1320 | 0.1129 | 0.2428 | 0.0316 | 0.3164 | 0.0048 | 0.2124 | 0.0001 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0008 | 0.0360 | 0.0079 | 0.0843 | 0.0254 | 0.1595 | 0.0409 | 0.2364 | 0.0926 | 0.2711 | 0.2669 | 0.1995 | 0.5654 | 0.0875 | 0.2991 | 0.1970 | 0.2991 | 0.2239 | 0.2057 | 0.2071 | 0.1218 | 0.1517 | 0.0503 | 0.0847 | 0.0160 | 0.0376 | 0.0044 | 0.0092 | 0.0036 | 0.0012 | 0.0000 | 0.0072 | 0.0439 | 0.0969 | 0.1605 | 0.2046 | 0.1989 | 0.1608 | 0.0959 | 0.0313 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 346 | 701 | | 14198 | 40387 | 106.4 | 32.10 | 146.17 | 188.92 | 72 | 82 | 90 | 96 | 103 | 110 | 118 | 129 | 144 | 0.0393 | 1589 | 0.755 | 201.22 | 48.27 | 2 | 0.0373 | 529 | 0.0026 | 18.07 | 6.363 | 0.2881 | 12345.6 | 1580000 | 229000000 | 39000000000 | 0.4708 | 0.1852 | 0.0007 | 0.0001 | 0.0041 | 0.0010 | 0.0119 | 0.0011 | 0.0333 | 0.0042 | 0.0850 | 0.0218 | 0.1598 | 0.0539 | 0.1708 | 0.0533 | 0.1970 | 0.0847 | 0.3372 | 0.7798 | 0.0002 | 0.0000 | 0.0011 | 0.0001 | 0.0015 | 0.0003 | 0.0096 | 0.0013 | 0.0331 | 0.0130 | 0.0687 | 0.0281 | 0.0706 | 0.0210 | 0.1052 | 0.0352 | 0.7101 | 0.9010 | 0.0061 | 0.0103 | 0.0105 | 0.0240 | 0.0243 | 0.0326 | 0.0723 | 0.1021 | 0.1348 | 0.1501 | 0.1713 | 0.1827 | 0.1203 | 0.1226 | 0.1413 | 0.1389 | 0.3190 | 0.2367 | 0.0017 | 0.0051 | 0.0119 | 0.0353 | 0.0818 | 0.1125 | 0.1127 | 0.1276 | 0.5114 | 12 | 14 | 17 | 21 | 38 | 97 | 181 | 289 | 433 | 0.0636 | 63.25 | 5.587 | 0.4594 | 57055.8 | 29900000 | 18300000000 | 12600000000000 | 0.5337 | 0.1336 | 0.0936 | 0.0033 | 0.2406 | 0.0356 | 0.2573 | 0.2023 | 0.1157 | 0.1813 | 0.1154 | 0.1677 | 0.0874 | 0.1514 | 0.0464 | 0.0816 | 0.0283 | 0.0770 | 0.0152 | 0.0996 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0022 | 0.0010 | 0.0084 | 0.0066 | 0.0488 | 0.0425 | 0.1001 | 0.0859 | 0.0667 | 0.0576 | 0.0957 | 0.0872 | 0.6770 | 0.7188 | 0.0006 | 0.0001 | 0.0009 | 0.0017 | 0.0039 | 0.0037 | 0.0107 | 0.0152 | 0.0648 | 0.0721 | 0.1272 | 0.1439 | 0.0905 | 0.0989 | 0.1204 | 0.1231 | 0.5809 | 0.5414 | 0.0005 | 0.0010 | 0.0023 | 0.0103 | 0.0565 | 0.1095 | 0.0807 | 0.1143 | 0.6250 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 873 | 826 | | 3064 | 6137 | 665.1 | 116.47 | 15.42 | 8.04 | 492 | 567 | 616 | 649 | 680 | 707 | 733 | 763 | 800 | 0.0893 | 548 | 0.993 | 122.00 | 37.22 | 1 | 0.0979 | 300 | 0.0008 | 64.26 | 7.305 | 0.1764 | 455869.0 | 321000000 | 230000000000 | 169000000000000 | 0.4008 | 0.2360 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0026 | 0.0000 | 0.0061 | 0.0010 | 0.0299 | 0.0170 | 0.0464 | 0.0304 | 0.0438 | 0.0180 | 0.0520 | 0.0277 | 0.8189 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0010 | 0.0186 | 0.0166 | 0.0266 | 0.0282 | 0.0190 | 0.0159 | 0.0274 | 0.0239 | 0.9060 | 0.9143 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0031 | 0.0000 | 0.0563 | 0.0000 | 0.0875 | 0.0000 | 0.1125 | 0.0000 | 0.0906 | 0.0000 | 0.1125 | 0.0000 | 0.5313 | 0.0000 | 0.0006 | 0.0053 | 0.0029 | 0.0135 | 0.0224 | 0.0494 | 0.0371 | 0.0530 | 0.8158 | 9 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 25 | 0.3326 | 0.28 | 1.109 | 0.7287 | 302.3 | 7707.87 | 246475 | 9230000 | 0.5740 | 0.1078 | 0.0370 | 0.0041 | 0.0648 | 0.0041 | 0.1039 | 0.0126 | 0.1337 | 0.0236 | 0.1566 | 0.0577 | 0.1880 | 0.1004 | 0.1606 | 0.1497 | 0.1151 | 0.2427 | 0.0403 | 0.4050 | 0.0184 | 0.0004 | 0.0317 | 0.0011 | 0.0455 | 0.0041 | 0.0608 | 0.0114 | 0.0782 | 0.0408 | 0.0945 | 0.0788 | 0.0862 | 0.1063 | 0.1277 | 0.1658 | 0.4570 | 0.5914 | 0.0395 | 0.0410 | 0.0482 | 0.0420 | 0.0556 | 0.0400 | 0.0649 | 0.0470 | 0.0803 | 0.0561 | 0.0770 | 0.0681 | 0.0663 | 0.0681 | 0.1071 | 0.1692 | 0.4612 | 0.4685 | 0.0423 | 0.0379 | 0.0347 | 0.0520 | 0.0863 | 0.1089 | 0.1044 | 0.1262 | 0.4073 |