High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1168 | 309 | | 5738 | 14541 | 555.0 | 97.99 | 135.57 | 201.88 | 430 | 475 | 509 | 532 | 549 | 569 | 595 | 630 | 674 | 0.0558 | 812 | 1.022 | 61.39 | 19.31 | 1 | 0.0284 | 163 | 0.0013 | 20.75 | 6.963 | 0.2451 | 317645.0 | 187000000 | 114000000000 | 71800000000000 | 0.4110 | 0.2319 | 0.0002 | 0.0000 | 0.0005 | 0.0002 | 0.0016 | 0.0000 | 0.0094 | 0.0011 | 0.0237 | 0.0134 | 0.0434 | 0.0246 | 0.0556 | 0.0175 | 0.0657 | 0.0266 | 0.8000 | 0.9168 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0002 | 0.0111 | 0.0115 | 0.0231 | 0.0207 | 0.0271 | 0.0101 | 0.0293 | 0.0171 | 0.9045 | 0.9404 | 0.0060 | 0.0000 | 0.0119 | 0.0000 | 0.0179 | 0.0000 | 0.0448 | 0.0000 | 0.0746 | 0.0000 | 0.0896 | 0.0000 | 0.0940 | 0.0000 | 0.1284 | 0.0000 | 0.5328 | 0.0000 | 0.0037 | 0.0078 | 0.0108 | 0.0257 | 0.0310 | 0.0518 | 0.0567 | 0.0712 | 0.7411 | 6 | 9 | 11 | 15 | 31 | 63 | 129 | 257 | 447 | 0.0557 | 17.52 | 4.450 | 0.4770 | 59131.7 | 35000000 | 24100000000 | 18500000000000 | 0.2802 | 0.3316 | 0.0685 | 0.0029 | 0.2066 | 0.0315 | 0.2433 | 0.1562 | 0.1601 | 0.1358 | 0.1039 | 0.1713 | 0.0844 | 0.1871 | 0.0648 | 0.1125 | 0.0391 | 0.0857 | 0.0293 | 0.1171 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0017 | 0.0011 | 0.0106 | 0.0101 | 0.0494 | 0.0398 | 0.0811 | 0.0787 | 0.0552 | 0.0482 | 0.0684 | 0.0622 | 0.7334 | 0.7591 | 0.0000 | 0.0008 | 0.0005 | 0.0014 | 0.0036 | 0.0028 | 0.0137 | 0.0194 | 0.0588 | 0.0540 | 0.0975 | 0.1111 | 0.0629 | 0.0684 | 0.0890 | 0.0925 | 0.6741 | 0.6495 | 0.0002 | 0.0007 | 0.0019 | 0.0127 | 0.0514 | 0.0927 | 0.0561 | 0.0791 | 0.7052 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 857 | 519 | | 7896 | 25086 | 549.1 | 111.64 | 115.29 | 108.29 | 407 | 452 | 487 | 515 | 543 | 571 | 603 | 640 | 694 | 0.0453 | 1137 | 0.998 | 121.50 | 33.97 | 1 | 0.0384 | 303 | 0.0006 | 71.62 | 7.693 | 0.1462 | 313964.0 | 187000000 | 115000000000 | 73300000000000 | 0.4442 | 0.2062 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0110 | 0.0013 | 0.0526 | 0.0162 | 0.1198 | 0.0335 | 0.1264 | 0.0258 | 0.1582 | 0.0429 | 0.5295 | 0.8802 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0000 | 0.0247 | 0.0109 | 0.0576 | 0.0223 | 0.0544 | 0.0138 | 0.0738 | 0.0246 | 0.7850 | 0.9284 | 0.0055 | 0.0067 | 0.0079 | 0.0134 | 0.0259 | 0.0235 | 0.0715 | 0.0705 | 0.1155 | 0.1779 | 0.1595 | 0.2315 | 0.1147 | 0.1409 | 0.1304 | 0.1342 | 0.3692 | 0.2013 | 0.0003 | 0.0021 | 0.0045 | 0.0279 | 0.0760 | 0.1244 | 0.0942 | 0.1323 | 0.5384 | 14 | 19 | 30 | 51 | 80 | 116 | 158 | 205 | 271 | 0.0163 | 18.42 | 5.849 | 0.4162 | 25016.0 | 7180000 | 2480000000 | 993000000000 | 0.4965 | 0.1507 | 0.0497 | 0.0008 | 0.2062 | 0.0128 | 0.2854 | 0.1255 | 0.1474 | 0.1729 | 0.1169 | 0.1868 | 0.0873 | 0.1793 | 0.0490 | 0.1096 | 0.0336 | 0.0972 | 0.0245 | 0.1151 | 0.0003 | 0.0000 | 0.0008 | 0.0004 | 0.0022 | 0.0018 | 0.0130 | 0.0103 | 0.0633 | 0.0528 | 0.1135 | 0.0937 | 0.0729 | 0.0627 | 0.1138 | 0.0990 | 0.6201 | 0.6793 | 0.0006 | 0.0004 | 0.0013 | 0.0031 | 0.0045 | 0.0078 | 0.0266 | 0.0355 | 0.0880 | 0.1026 | 0.1507 | 0.1609 | 0.0929 | 0.1075 | 0.1339 | 0.1393 | 0.5016 | 0.4429 | 0.0004 | 0.0013 | 0.0028 | 0.0194 | 0.0737 | 0.1338 | 0.0833 | 0.1256 | 0.5598 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 959 | 713 | | 6139 | 10848 | 256.2 | 53.54 | 207.18 | 194.13 | 190 | 210 | 225 | 238 | 252 | 266 | 283 | 302 | 326 | 0.0678 | 736 | 1.177 | 102.18 | 37.66 | 1 | 0.0415 | 255 | 0.0008 | 47.93 | 7.299 | 0.1591 | 68517.0 | 19100000 | 5540000000 | 1670000000000 | 0.4834 | 0.1799 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0032 | 0.0003 | 0.0156 | 0.0014 | 0.0740 | 0.0133 | 0.1454 | 0.0377 | 0.1504 | 0.0343 | 0.1835 | 0.0591 | 0.4267 | 0.8538 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0002 | 0.0059 | 0.0012 | 0.0355 | 0.0092 | 0.0646 | 0.0250 | 0.0616 | 0.0171 | 0.0826 | 0.0290 | 0.7478 | 0.9183 | 0.0067 | 0.0235 | 0.0114 | 0.0141 | 0.0352 | 0.0469 | 0.0856 | 0.1643 | 0.1369 | 0.1925 | 0.1835 | 0.2207 | 0.1274 | 0.0845 | 0.1340 | 0.0986 | 0.2795 | 0.1549 | 0.0024 | 0.0041 | 0.0093 | 0.0368 | 0.0764 | 0.1195 | 0.1012 | 0.1326 | 0.5176 | 19 | 34 | 61 | 103 | 155 | 210 | 274 | 353 | 472 | 0.0078 | 34.55 | 6.449 | 0.3311 | 80606.7 | 42400000 | 27300000000 | 20400000000000 | 0.4122 | 0.2269 | 0.0375 | 0.0010 | 0.1827 | 0.0076 | 0.2438 | 0.0851 | 0.1774 | 0.1506 | 0.1360 | 0.1962 | 0.1064 | 0.2035 | 0.0572 | 0.1157 | 0.0420 | 0.0994 | 0.0171 | 0.1407 | 0.0008 | 0.0002 | 0.0010 | 0.0012 | 0.0031 | 0.0027 | 0.0179 | 0.0119 | 0.0702 | 0.0586 | 0.1159 | 0.1040 | 0.0844 | 0.0695 | 0.1125 | 0.0949 | 0.5943 | 0.6571 | 0.0016 | 0.0020 | 0.0038 | 0.0020 | 0.0071 | 0.0076 | 0.0245 | 0.0311 | 0.0919 | 0.0967 | 0.1321 | 0.1652 | 0.1025 | 0.1119 | 0.1394 | 0.1317 | 0.4971 | 0.4518 | 0.0016 | 0.0016 | 0.0043 | 0.0200 | 0.0832 | 0.1402 | 0.0836 | 0.1216 | 0.5440 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 150 | 710 | | 6177 | 14509 | 257.7 | 49.98 | 159.94 | 175.38 | 195 | 216 | 230 | 243 | 255 | 267 | 280 | 296 | 323 | 0.0733 | 1064 | 0.993 | 123.79 | 34.53 | 1 | 0.0478 | 295 | 0.0009 | 53.18 | 7.248 | 0.1699 | 68920.1 | 19100000 | 5500000000 | 1640000000000 | 0.4318 | 0.2171 | 0.0000 | 0.0000 | 0.0009 | 0.0002 | 0.0030 | 0.0002 | 0.0173 | 0.0017 | 0.0536 | 0.0129 | 0.0983 | 0.0305 | 0.1154 | 0.0290 | 0.1599 | 0.0498 | 0.5517 | 0.8757 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0013 | 0.0000 | 0.0044 | 0.0013 | 0.0238 | 0.0098 | 0.0441 | 0.0207 | 0.0492 | 0.0117 | 0.0819 | 0.0218 | 0.7949 | 0.9346 | 0.0103 | 0.0328 | 0.0091 | 0.0437 | 0.0343 | 0.1202 | 0.0926 | 0.1421 | 0.1669 | 0.1585 | 0.1829 | 0.1530 | 0.1291 | 0.0710 | 0.1451 | 0.1202 | 0.2297 | 0.1585 | 0.0007 | 0.0031 | 0.0099 | 0.0358 | 0.0782 | 0.1328 | 0.1171 | 0.1540 | 0.4684 | 16 | 20 | 33 | 57 | 93 | 139 | 201 | 286 | 409 | 0.0208 | 27.02 | 5.804 | 0.4346 | 56339.0 | 28300000 | 18000000000 | 13700000000000 | 0.5203 | 0.1387 | 0.0476 | 0.0018 | 0.1694 | 0.0111 | 0.2272 | 0.1026 | 0.1326 | 0.1244 | 0.1282 | 0.1647 | 0.1104 | 0.1591 | 0.0736 | 0.1121 | 0.0615 | 0.1069 | 0.0495 | 0.2172 | 0.0002 | 0.0000 | 0.0018 | 0.0007 | 0.0049 | 0.0018 | 0.0131 | 0.0102 | 0.0685 | 0.0529 | 0.1030 | 0.0883 | 0.0768 | 0.0614 | 0.1123 | 0.0986 | 0.6194 | 0.6860 | 0.0007 | 0.0003 | 0.0022 | 0.0038 | 0.0046 | 0.0082 | 0.0208 | 0.0260 | 0.0828 | 0.0984 | 0.1265 | 0.1386 | 0.0956 | 0.0989 | 0.1283 | 0.1435 | 0.5386 | 0.4824 | 0.0004 | 0.0027 | 0.0042 | 0.0175 | 0.0747 | 0.1189 | 0.0808 | 0.1256 | 0.5753 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 789 | 385 | | 5318 | 5252 | 117.1 | 28.29 | 183.50 | 149.81 | 88 | 95 | 101 | 106 | 111 | 118 | 126 | 135 | 153 | 0.1359 | 714 | 1.185 | 99.25 | 31.11 | 1 | 0.0440 | 234 | 0.0038 | 12.98 | 5.962 | 0.3134 | 14501.7 | 1920000 | 277000000 | 44100000000 | 0.4157 | 0.2302 | 0.0009 | 0.0000 | 0.0020 | 0.0000 | 0.0054 | 0.0000 | 0.0148 | 0.0014 | 0.0594 | 0.0200 | 0.1213 | 0.0451 | 0.1410 | 0.0401 | 0.1627 | 0.0615 | 0.4926 | 0.8319 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0000 | 0.0092 | 0.0002 | 0.0304 | 0.0127 | 0.0533 | 0.0251 | 0.0612 | 0.0134 | 0.0839 | 0.0215 | 0.7570 | 0.9271 | 0.0036 | 0.0085 | 0.0107 | 0.0142 | 0.0130 | 0.0342 | 0.0627 | 0.0883 | 0.1456 | 0.2023 | 0.1692 | 0.1766 | 0.0994 | 0.0855 | 0.1669 | 0.1595 | 0.3290 | 0.2308 | 0.0013 | 0.0072 | 0.0103 | 0.0354 | 0.0752 | 0.1150 | 0.1115 | 0.1352 | 0.5090 | 34 | 56 | 79 | 108 | 140 | 180 | 233 | 298 | 398 | 0.0028 | 51.84 | 6.696 | 0.3006 | 56111.0 | 22900000 | 11200000000 | 6260000000000 | 0.5751 | 0.1077 | 0.0275 | 0.0017 | 0.1066 | 0.0098 | 0.2575 | 0.0574 | 0.1760 | 0.1074 | 0.1701 | 0.1895 | 0.1401 | 0.1959 | 0.0671 | 0.1430 | 0.0299 | 0.1310 | 0.0251 | 0.1643 | 0.0008 | 0.0000 | 0.0024 | 0.0010 | 0.0052 | 0.0029 | 0.0226 | 0.0226 | 0.0755 | 0.0634 | 0.1156 | 0.0976 | 0.0898 | 0.0789 | 0.1017 | 0.0957 | 0.5866 | 0.6379 | 0.0012 | 0.0007 | 0.0024 | 0.0052 | 0.0125 | 0.0163 | 0.0458 | 0.0570 | 0.0903 | 0.1117 | 0.1729 | 0.1805 | 0.1028 | 0.1139 | 0.1147 | 0.1220 | 0.4575 | 0.3928 | 0.0005 | 0.0044 | 0.0068 | 0.0311 | 0.0856 | 0.1465 | 0.0934 | 0.1226 | 0.5090 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 680 | 102 | | 4304 | 6744 | 541.8 | 144.02 | 32.62 | 45.34 | 329 | 395 | 450 | 516 | 566 | 606 | 638 | 670 | 705 | 0.0948 | 639 | 0.542 | 117.00 | 26.02 | 1 | 0.0853 | 367 | 0.0008 | 32.43 | 7.325 | 0.2185 | 314288.0 | 192000000 | 122000000000 | 80400000000000 | 0.3875 | 0.2444 | 0.0010 | 0.0000 | 0.0025 | 0.0003 | 0.0069 | 0.0003 | 0.0212 | 0.0022 | 0.0562 | 0.0210 | 0.0877 | 0.0339 | 0.0946 | 0.0234 | 0.1252 | 0.0358 | 0.6047 | 0.8831 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0006 | 0.0003 | 0.0044 | 0.0015 | 0.0197 | 0.0172 | 0.0292 | 0.0288 | 0.0251 | 0.0175 | 0.0368 | 0.0275 | 0.8842 | 0.9070 | 0.0000 | 0.0000 | 0.0080 | 0.0000 | 0.0187 | 0.0000 | 0.0276 | 0.0000 | 0.0480 | 0.0000 | 0.0730 | 0.0000 | 0.0747 | 0.0000 | 0.1103 | 0.0000 | 0.6397 | 1.0000 | 0.0000 | 0.0013 | 0.0017 | 0.0055 | 0.0233 | 0.0355 | 0.0364 | 0.0508 | 0.8455 | 8 | 9 | 11 | 12 | 15 | 18 | 26 | 44 | 83 | 0.2567 | 1.27 | 2.377 | 0.7837 | 3119.9 | 589671 | 172000000 | 67600000000 | 0.6419 | 0.0827 | 0.0252 | 0.0246 | 0.1124 | 0.0419 | 0.1550 | 0.0583 | 0.2190 | 0.0887 | 0.1725 | 0.1297 | 0.1570 | 0.1478 | 0.1066 | 0.1445 | 0.0504 | 0.1650 | 0.0019 | 0.1995 | 0.0035 | 0.0115 | 0.0080 | 0.0167 | 0.0141 | 0.0199 | 0.0251 | 0.0267 | 0.0693 | 0.0554 | 0.1065 | 0.0940 | 0.0749 | 0.0737 | 0.0965 | 0.0992 | 0.6020 | 0.6029 | 0.0034 | 0.0031 | 0.0054 | 0.0085 | 0.0075 | 0.0124 | 0.0360 | 0.0325 | 0.0658 | 0.0688 | 0.1126 | 0.1145 | 0.0855 | 0.0828 | 0.1119 | 0.1121 | 0.5719 | 0.5654 | 0.0012 | 0.0070 | 0.0153 | 0.0282 | 0.0728 | 0.1045 | 0.0752 | 0.1057 | 0.5901 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 463 | 730 | | 6826 | 14133 | 120.4 | 23.00 | 116.76 | 79.84 | 93 | 102 | 108 | 113 | 119 | 124 | 130 | 137 | 150 | 0.0723 | 1022 | 1.085 | 103.16 | 28.18 | 1 | 0.0349 | 238 | 0.0037 | 11.96 | 5.947 | 0.3160 | 15021.5 | 1940000 | 260000000 | 36200000000 | 0.4335 | 0.2237 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0044 | 0.0009 | 0.0154 | 0.0017 | 0.0519 | 0.0164 | 0.0996 | 0.0314 | 0.1171 | 0.0321 | 0.1581 | 0.0575 | 0.5524 | 0.8598 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0003 | 0.0060 | 0.0004 | 0.0250 | 0.0105 | 0.0473 | 0.0218 | 0.0483 | 0.0136 | 0.0723 | 0.0276 | 0.7998 | 0.9258 | 0.0111 | 0.0195 | 0.0101 | 0.0469 | 0.0364 | 0.0703 | 0.1083 | 0.1367 | 0.1447 | 0.1680 | 0.1903 | 0.1992 | 0.1326 | 0.0977 | 0.1164 | 0.1094 | 0.2500 | 0.1523 | 0.0021 | 0.0061 | 0.0177 | 0.0360 | 0.0903 | 0.1196 | 0.1114 | 0.1422 | 0.4745 | 27 | 44 | 61 | 81 | 101 | 124 | 151 | 182 | 227 | 0.0032 | 25.81 | 6.449 | 0.3268 | 20005.6 | 4300000 | 1080000000 | 305000000000 | 0.5926 | 0.1078 | 0.0158 | 0.0022 | 0.1055 | 0.0083 | 0.2116 | 0.0336 | 0.1858 | 0.0797 | 0.1786 | 0.1495 | 0.1481 | 0.2016 | 0.0911 | 0.1603 | 0.0466 | 0.1718 | 0.0169 | 0.1931 | 0.0011 | 0.0005 | 0.0019 | 0.0017 | 0.0046 | 0.0033 | 0.0183 | 0.0093 | 0.0620 | 0.0454 | 0.1196 | 0.0892 | 0.1019 | 0.0765 | 0.1366 | 0.1110 | 0.5541 | 0.6630 | 0.0017 | 0.0050 | 0.0065 | 0.0107 | 0.0178 | 0.0259 | 0.0421 | 0.0517 | 0.1004 | 0.1214 | 0.1658 | 0.1753 | 0.1211 | 0.1343 | 0.1429 | 0.1473 | 0.4017 | 0.3284 | 0.0007 | 0.0028 | 0.0097 | 0.0328 | 0.0821 | 0.1460 | 0.1176 | 0.1387 | 0.4696 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 241 | 848 | | 10173 | 33400 | 558.7 | 106.36 | 141.20 | 210.07 | 440 | 469 | 494 | 517 | 539 | 564 | 595 | 638 | 721 | 0.0340 | 1136 | 1.181 | 125.88 | 48.08 | 1 | 0.0321 | 327 | 0.0010 | 33.71 | 7.169 | 0.1994 | 323447.0 | 194000000 | 121000000000 | 78500000000000 | 0.3999 | 0.2475 | 0.0004 | 0.0002 | 0.0009 | 0.0001 | 0.0027 | 0.0002 | 0.0123 | 0.0021 | 0.0344 | 0.0148 | 0.0701 | 0.0282 | 0.0822 | 0.0219 | 0.1201 | 0.0283 | 0.6769 | 0.9042 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0077 | 0.0002 | 0.0193 | 0.0092 | 0.0401 | 0.0151 | 0.0464 | 0.0088 | 0.0651 | 0.0146 | 0.8195 | 0.9521 | 0.0060 | 0.0020 | 0.0079 | 0.0101 | 0.0113 | 0.0061 | 0.0344 | 0.0869 | 0.0656 | 0.1212 | 0.0947 | 0.2222 | 0.0742 | 0.1253 | 0.0947 | 0.1616 | 0.6113 | 0.2646 | 0.0019 | 0.0063 | 0.0137 | 0.0288 | 0.0574 | 0.1020 | 0.0876 | 0.1004 | 0.6019 | 7 | 9 | 12 | 16 | 31 | 71 | 144 | 264 | 446 | 0.0759 | 52.63 | 5.308 | 0.4892 | 64064.9 | 41000000 | 31800000000 | 28400000000000 | 0.3985 | 0.2299 | 0.1332 | 0.0028 | 0.3108 | 0.0481 | 0.2982 | 0.2452 | 0.1039 | 0.2139 | 0.0716 | 0.1845 | 0.0484 | 0.1328 | 0.0222 | 0.0737 | 0.0081 | 0.0576 | 0.0035 | 0.0413 | 0.0002 | 0.0002 | 0.0008 | 0.0002 | 0.0013 | 0.0007 | 0.0107 | 0.0085 | 0.0677 | 0.0583 | 0.1067 | 0.0940 | 0.0684 | 0.0620 | 0.1038 | 0.0989 | 0.6404 | 0.6771 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0018 | 0.0038 | 0.0161 | 0.0195 | 0.0838 | 0.0907 | 0.1222 | 0.1354 | 0.0813 | 0.0869 | 0.1259 | 0.1305 | 0.5681 | 0.5326 | 0.0003 | 0.0006 | 0.0013 | 0.0134 | 0.0759 | 0.1150 | 0.0717 | 0.1123 | 0.6096 | ||
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 787 | 786 | | 14112 | 32367 | 245.5 | 77.16 | 146.77 | 228.26 | 156 | 185 | 205 | 221 | 237 | 254 | 274 | 301 | 345 | 0.0488 | 1581 | 0.669 | 148.12 | 27.73 | 3 | 0.0257 | 363 | 0.0006 | 60.19 | 7.782 | 0.1687 | 66225.0 | 19500000 | 6230000000 | 2150000000000 | 0.4164 | 0.2099 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0068 | 0.0005 | 0.0211 | 0.0043 | 0.0673 | 0.0249 | 0.1414 | 0.0502 | 0.1309 | 0.0527 | 0.1587 | 0.0666 | 0.4724 | 0.8007 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0003 | 0.0074 | 0.0026 | 0.0218 | 0.0131 | 0.0526 | 0.0251 | 0.0492 | 0.0237 | 0.0741 | 0.0308 | 0.7916 | 0.9043 | 0.0010 | 0.0021 | 0.0033 | 0.0076 | 0.0118 | 0.0125 | 0.0393 | 0.0569 | 0.1035 | 0.1090 | 0.1432 | 0.1444 | 0.0996 | 0.0938 | 0.1288 | 0.1146 | 0.4695 | 0.4590 | 0.0005 | 0.0024 | 0.0074 | 0.0199 | 0.0565 | 0.1073 | 0.0842 | 0.1154 | 0.6063 | 13 | 15 | 17 | 22 | 34 | 66 | 132 | 244 | 448 | 0.0654 | 39.84 | 4.972 | 0.5439 | 73640.4 | 55300000 | 50400000000 | 51700000000000 | 0.5011 | 0.1602 | 0.0623 | 0.0031 | 0.2185 | 0.0242 | 0.2928 | 0.1386 | 0.1538 | 0.1668 | 0.1059 | 0.2014 | 0.0738 | 0.1699 | 0.0455 | 0.1175 | 0.0254 | 0.0808 | 0.0220 | 0.0977 | 0.0000 | 0.0003 | 0.0009 | 0.0002 | 0.0020 | 0.0009 | 0.0125 | 0.0097 | 0.0604 | 0.0529 | 0.0922 | 0.0798 | 0.0683 | 0.0642 | 0.1028 | 0.0895 | 0.6609 | 0.7026 | 0.0001 | 0.0004 | 0.0013 | 0.0019 | 0.0031 | 0.0054 | 0.0184 | 0.0221 | 0.0771 | 0.0786 | 0.1154 | 0.1217 | 0.0827 | 0.0911 | 0.1160 | 0.1245 | 0.5858 | 0.5543 | 0.0004 | 0.0009 | 0.0021 | 0.0159 | 0.0682 | 0.1066 | 0.0762 | 0.1087 | 0.6210 | ||
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 395 | 909 | | 589 | 5786 | 12.0 | 2.37 | 6.24 | 2.23 | 9 | 10 | 11 | 11 | 12 | 12 | 13 | 14 | 15 | 0.0990 | 573 | 0.731 | 73.43 | 17.00 | 0 | 0.3192 | 188 | 0.0185 | 6.32 | 4.289 | 0.3960 | 150.6 | 1953.66 | 26252.6 | 364792 | 0.3695 | 0.2656 | 0.0046 | 0.0000 | 0.0069 | 0.0018 | 0.0324 | 0.0036 | 0.0694 | 0.0164 | 0.1019 | 0.0455 | 0.1343 | 0.0764 | 0.1898 | 0.1218 | 0.1736 | 0.1818 | 0.2870 | 0.5527 | 0.0000 | 0.0000 | 0.0077 | 0.0000 | 0.0174 | 0.0017 | 0.0367 | 0.0156 | 0.0405 | 0.0363 | 0.0656 | 0.0554 | 0.1158 | 0.0606 | 0.1409 | 0.1125 | 0.5753 | 0.7180 | 0.0581 | 0.2857 | 0.0930 | 0.2500 | 0.1860 | 0.1071 | 0.1163 | 0.1786 | 0.1744 | 0.1071 | 0.1163 | 0.0714 | 0.0814 | 0.0000 | 0.1163 | 0.0000 | 0.0581 | 0.0000 | 0.0153 | 0.0337 | 0.0706 | 0.0982 | 0.1135 | 0.1350 | 0.1380 | 0.1503 | 0.2454 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0198 | 11.10 | 4.314 | 0.3248 | 43.9 | 336.777 | 2778.03 | 24382.5 | 0.5530 | 0.1191 | 0.0068 | 0.0000 | 0.0407 | 0.0041 | 0.1143 | 0.0182 | 0.2166 | 0.0597 | 0.2673 | 0.1261 | 0.2088 | 0.2311 | 0.1023 | 0.2725 | 0.0370 | 0.2133 | 0.0062 | 0.0750 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0121 | 0.0032 | 0.0364 | 0.0132 | 0.0907 | 0.0355 | 0.1684 | 0.0778 | 0.2678 | 0.1906 | 0.2778 | 0.3647 | 0.1454 | 0.3144 | 0.1144 | 0.2816 | 0.2397 | 0.3609 | 0.2950 | 0.2346 | 0.1896 | 0.0927 | 0.1073 | 0.0268 | 0.0392 | 0.0034 | 0.0141 | 0.0000 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0090 | 0.0356 | 0.0844 | 0.1569 | 0.2511 | 0.2490 | 0.1644 | 0.0477 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 899 | 757 | | 8961 | 31826 | 259.4 | 53.09 | 114.61 | 165.16 | 194 | 214 | 228 | 242 | 255 | 268 | 283 | 301 | 329 | 0.0403 | 1284 | 0.981 | 97.80 | 29.12 | 1 | 0.0280 | 251 | 0.0008 | 53.17 | 7.402 | 0.1637 | 70101.1 | 19700000 | 5780000000 | 1760000000000 | 0.4503 | 0.2063 | 0.0000 | 0.0001 | 0.0002 | 0.0000 | 0.0018 | 0.0004 | 0.0136 | 0.0014 | 0.0585 | 0.0160 | 0.1232 | 0.0320 | 0.1410 | 0.0288 | 0.1844 | 0.0435 | 0.4773 | 0.8778 | 0.0000 | 0.0001 | 0.0001 | 0.0000 | 0.0009 | 0.0001 | 0.0065 | 0.0007 | 0.0298 | 0.0108 | 0.0551 | 0.0198 | 0.0629 | 0.0145 | 0.0877 | 0.0191 | 0.7569 | 0.9349 | 0.0085 | 0.0127 | 0.0157 | 0.0127 | 0.0264 | 0.0204 | 0.0883 | 0.0992 | 0.1254 | 0.1476 | 0.1645 | 0.1730 | 0.1132 | 0.1374 | 0.1204 | 0.1527 | 0.3376 | 0.2443 | 0.0009 | 0.0040 | 0.0076 | 0.0301 | 0.0767 | 0.1303 | 0.1175 | 0.1407 | 0.4922 | 9 | 11 | 13 | 18 | 27 | 57 | 118 | 210 | 350 | 0.0979 | 28.78 | 4.781 | 0.5522 | 40414.6 | 20400000 | 12400000000 | 8610000000000 | 0.4405 | 0.1958 | 0.0756 | 0.0022 | 0.2289 | 0.0229 | 0.3344 | 0.1478 | 0.1476 | 0.1783 | 0.1070 | 0.2271 | 0.0571 | 0.1822 | 0.0288 | 0.0945 | 0.0118 | 0.0738 | 0.0087 | 0.0711 | 0.0002 | 0.0002 | 0.0001 | 0.0006 | 0.0010 | 0.0013 | 0.0093 | 0.0067 | 0.0501 | 0.0437 | 0.0928 | 0.0740 | 0.0638 | 0.0544 | 0.0943 | 0.0837 | 0.6883 | 0.7355 | 0.0002 | 0.0003 | 0.0008 | 0.0008 | 0.0015 | 0.0033 | 0.0136 | 0.0144 | 0.0615 | 0.0722 | 0.1163 | 0.1254 | 0.0773 | 0.0817 | 0.1147 | 0.1218 | 0.6140 | 0.5802 | 0.0004 | 0.0001 | 0.0011 | 0.0101 | 0.0596 | 0.1019 | 0.0697 | 0.1103 | 0.6467 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 325 | 775 | | 8514 | 19749 | 254.9 | 63.33 | 136.94 | 217.87 | 181 | 199 | 215 | 230 | 245 | 263 | 284 | 310 | 345 | 0.0554 | 1094 | 1.015 | 113.32 | 27.78 | 1 | 0.0297 | 253 | 0.0007 | 62.36 | 7.567 | 0.1617 | 68980.3 | 19800000 | 5980000000 | 1900000000000 | 0.4391 | 0.2068 | 0.0011 | 0.0003 | 0.0017 | 0.0003 | 0.0064 | 0.0005 | 0.0289 | 0.0021 | 0.0852 | 0.0200 | 0.1632 | 0.0545 | 0.1589 | 0.0468 | 0.1657 | 0.0841 | 0.3889 | 0.7914 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0002 | 0.0093 | 0.0012 | 0.0318 | 0.0115 | 0.0627 | 0.0281 | 0.0665 | 0.0189 | 0.0802 | 0.0354 | 0.7455 | 0.9046 | 0.0011 | 0.0129 | 0.0048 | 0.0145 | 0.0117 | 0.0338 | 0.0490 | 0.0900 | 0.1087 | 0.1849 | 0.1695 | 0.2138 | 0.1317 | 0.1077 | 0.1359 | 0.1479 | 0.3875 | 0.1945 | 0.0016 | 0.0026 | 0.0085 | 0.0269 | 0.0708 | 0.1191 | 0.0930 | 0.1165 | 0.5610 | 12 | 14 | 16 | 18 | 24 | 48 | 109 | 230 | 450 | 0.0654 | 42.28 | 4.865 | 0.5213 | 66216.2 | 45500000 | 36800000000 | 33000000000000 | 0.5747 | 0.0897 | 0.0824 | 0.0046 | 0.2566 | 0.0341 | 0.3371 | 0.1863 | 0.1386 | 0.1780 | 0.0964 | 0.2125 | 0.0524 | 0.1720 | 0.0262 | 0.0876 | 0.0075 | 0.0710 | 0.0028 | 0.0539 | 0.0002 | 0.0005 | 0.0002 | 0.0002 | 0.0025 | 0.0009 | 0.0135 | 0.0136 | 0.0599 | 0.0488 | 0.1040 | 0.0963 | 0.0621 | 0.0576 | 0.0973 | 0.0891 | 0.6604 | 0.6931 | 0.0008 | 0.0018 | 0.0027 | 0.0016 | 0.0037 | 0.0040 | 0.0178 | 0.0162 | 0.0652 | 0.0702 | 0.1129 | 0.1134 | 0.0675 | 0.0720 | 0.1036 | 0.1107 | 0.6257 | 0.6101 | 0.0000 | 0.0009 | 0.0045 | 0.0148 | 0.0658 | 0.1032 | 0.0686 | 0.0979 | 0.6444 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1153 | 647 | | 7001 | 25505 | 556.6 | 122.04 | 346.05 | 471.05 | 401 | 439 | 476 | 515 | 554 | 594 | 633 | 670 | 719 | 0.0502 | 1281 | 1.091 | 94.40 | 31.32 | 2 | 0.0330 | 231 | 0.0008 | 49.47 | 7.389 | 0.1879 | 324688.0 | 198000000 | 125000000000 | 81200000000000 | 0.4396 | 0.2100 | 0.0007 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0002 | 0.0176 | 0.0008 | 0.0856 | 0.0167 | 0.1397 | 0.0345 | 0.1231 | 0.0336 | 0.1667 | 0.0500 | 0.4597 | 0.8643 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0003 | 0.0329 | 0.0127 | 0.0559 | 0.0246 | 0.0475 | 0.0180 | 0.0714 | 0.0252 | 0.7845 | 0.9193 | 0.0042 | 0.0190 | 0.0042 | 0.0521 | 0.0140 | 0.0474 | 0.0524 | 0.1232 | 0.1054 | 0.1943 | 0.1795 | 0.1848 | 0.1194 | 0.1327 | 0.1522 | 0.1137 | 0.3687 | 0.1327 | 0.0000 | 0.0026 | 0.0017 | 0.0185 | 0.0503 | 0.0888 | 0.0772 | 0.0943 | 0.6665 | 16 | 30 | 58 | 98 | 145 | 207 | 334 | 573 | 1040 | 0.0125 | 72.60 | 6.612 | 0.3697 | 341631.0 | 484000000 | 806000000000 | 1.47E+15 | 0.3657 | 0.3010 | 0.0271 | 0.0034 | 0.1024 | 0.0083 | 0.1982 | 0.0464 | 0.1992 | 0.1091 | 0.1937 | 0.1605 | 0.1274 | 0.2005 | 0.0763 | 0.1440 | 0.0457 | 0.1451 | 0.0301 | 0.1828 | 0.0006 | 0.0011 | 0.0022 | 0.0019 | 0.0049 | 0.0048 | 0.0175 | 0.0174 | 0.0458 | 0.0451 | 0.0736 | 0.0727 | 0.0584 | 0.0567 | 0.0751 | 0.0729 | 0.7219 | 0.7275 | 0.0005 | 0.0012 | 0.0032 | 0.0039 | 0.0065 | 0.0072 | 0.0159 | 0.0166 | 0.0490 | 0.0479 | 0.0772 | 0.0773 | 0.0599 | 0.0636 | 0.0830 | 0.0742 | 0.7047 | 0.7080 | 0.0005 | 0.0031 | 0.0048 | 0.0174 | 0.0468 | 0.0729 | 0.0592 | 0.0760 | 0.7193 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 536 | 592 | | 11784 | 41678 | 115.6 | 34.59 | 207.83 | 214.61 | 75 | 86 | 94 | 103 | 111 | 120 | 130 | 144 | 163 | 0.0416 | 1732 | 0.727 | 154.55 | 39.40 | 3 | 0.0386 | 455 | 0.0021 | 19.63 | 6.518 | 0.2766 | 14550.8 | 1990000 | 293000000 | 46400000000 | 0.4899 | 0.1699 | 0.0021 | 0.0004 | 0.0048 | 0.0007 | 0.0141 | 0.0032 | 0.0416 | 0.0077 | 0.1062 | 0.0329 | 0.1621 | 0.0738 | 0.1591 | 0.0708 | 0.1647 | 0.0991 | 0.3453 | 0.7113 | 0.0007 | 0.0001 | 0.0018 | 0.0005 | 0.0040 | 0.0013 | 0.0122 | 0.0039 | 0.0406 | 0.0176 | 0.0687 | 0.0392 | 0.0628 | 0.0280 | 0.0796 | 0.0464 | 0.7295 | 0.8631 | 0.0022 | 0.0025 | 0.0041 | 0.0115 | 0.0137 | 0.0329 | 0.0504 | 0.0873 | 0.1067 | 0.1853 | 0.1530 | 0.1919 | 0.1278 | 0.1227 | 0.1467 | 0.1524 | 0.3956 | 0.2133 | 0.0013 | 0.0036 | 0.0085 | 0.0266 | 0.0690 | 0.1142 | 0.0929 | 0.1140 | 0.5699 | 15 | 20 | 37 | 80 | 139 | 203 | 278 | 375 | 515 | 0.0215 | 74.38 | 6.685 | 0.3397 | 89248.9 | 51000000 | 34800000000 | 27200000000000 | 0.4252 | 0.2362 | 0.0235 | 0.0012 | 0.1173 | 0.0073 | 0.2179 | 0.0568 | 0.1485 | 0.1081 | 0.1623 | 0.1648 | 0.1467 | 0.2023 | 0.0826 | 0.1340 | 0.0615 | 0.1331 | 0.0396 | 0.1923 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0028 | 0.0018 | 0.0089 | 0.0066 | 0.0493 | 0.0407 | 0.0985 | 0.0784 | 0.0722 | 0.0592 | 0.0927 | 0.0831 | 0.6748 | 0.7298 | 0.0013 | 0.0008 | 0.0022 | 0.0025 | 0.0046 | 0.0081 | 0.0169 | 0.0211 | 0.0664 | 0.0802 | 0.1232 | 0.1307 | 0.0875 | 0.0958 | 0.1112 | 0.1158 | 0.5867 | 0.5449 | 0.0005 | 0.0023 | 0.0051 | 0.0144 | 0.0596 | 0.1114 | 0.0778 | 0.1061 | 0.6229 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1103 | 517 | | 8577 | 27567 | 251.0 | 73.86 | 67.12 | 106.49 | 158 | 187 | 212 | 231 | 249 | 269 | 291 | 317 | 347 | 0.0463 | 1277 | 0.999 | 61.74 | 14.87 | 3 | 0.0160 | 137 | 0.0006 | 49.24 | 7.634 | 0.1718 | 68432.9 | 19900000 | 6110000000 | 1960000000000 | 0.3917 | 0.2259 | 0.0010 | 0.0000 | 0.0014 | 0.0003 | 0.0060 | 0.0008 | 0.0247 | 0.0042 | 0.0651 | 0.0238 | 0.1257 | 0.0510 | 0.1228 | 0.0509 | 0.1551 | 0.0690 | 0.4982 | 0.8000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0003 | 0.0051 | 0.0018 | 0.0196 | 0.0121 | 0.0368 | 0.0218 | 0.0312 | 0.0145 | 0.0510 | 0.0223 | 0.8549 | 0.9273 | 0.0009 | 0.0040 | 0.0027 | 0.0132 | 0.0085 | 0.0238 | 0.0330 | 0.0886 | 0.0884 | 0.1799 | 0.1152 | 0.1786 | 0.1134 | 0.1310 | 0.1321 | 0.1481 | 0.5058 | 0.2328 | 0.0000 | 0.0028 | 0.0057 | 0.0164 | 0.0375 | 0.0805 | 0.0705 | 0.0898 | 0.6967 | 11 | 13 | 15 | 16 | 19 | 25 | 41 | 93 | 211 | 0.0930 | 8.04 | 3.824 | 0.6491 | 15845.6 | 5950000 | 2770000000 | 1510000000000 | 0.3766 | 0.2478 | 0.0298 | 0.0054 | 0.1067 | 0.0172 | 0.1592 | 0.0551 | 0.1827 | 0.1063 | 0.1820 | 0.1529 | 0.1451 | 0.1722 | 0.0871 | 0.1411 | 0.0659 | 0.1368 | 0.0416 | 0.2130 | 0.0004 | 0.0016 | 0.0017 | 0.0028 | 0.0045 | 0.0051 | 0.0117 | 0.0126 | 0.0354 | 0.0330 | 0.0450 | 0.0458 | 0.0377 | 0.0407 | 0.0557 | 0.0508 | 0.8078 | 0.8077 | 0.0000 | 0.0009 | 0.0007 | 0.0011 | 0.0037 | 0.0022 | 0.0114 | 0.0125 | 0.0389 | 0.0441 | 0.0647 | 0.0648 | 0.0431 | 0.0544 | 0.0638 | 0.0722 | 0.7737 | 0.7478 | 0.0011 | 0.0011 | 0.0023 | 0.0107 | 0.0370 | 0.0558 | 0.0367 | 0.0655 | 0.7899 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 353 | 558 | | 3264 | 13261 | 567.7 | 97.23 | 20.25 | 30.53 | 423 | 480 | 524 | 555 | 578 | 601 | 624 | 651 | 686 | 0.0525 | 696 | 0.829 | 83.26 | 24.17 | 2 | 0.0757 | 247 | 0.0012 | 24.55 | 6.947 | 0.2311 | 331741.0 | 199000000 | 122000000000 | 75900000000000 | 0.3761 | 0.2603 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0042 | 0.0015 | 0.0348 | 0.0117 | 0.0809 | 0.0329 | 0.0637 | 0.0151 | 0.0926 | 0.0194 | 0.7227 | 0.9195 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0012 | 0.0138 | 0.0117 | 0.0348 | 0.0322 | 0.0210 | 0.0129 | 0.0246 | 0.0169 | 0.9033 | 0.9251 | 0.0000 | 0.0000 | 0.0134 | 0.0000 | 0.0267 | 0.0000 | 0.0829 | 0.2000 | 0.1337 | 0.2000 | 0.2086 | 0.2000 | 0.1310 | 0.2000 | 0.1230 | 0.2000 | 0.2807 | 0.0000 | 0.0000 | 0.0011 | 0.0022 | 0.0117 | 0.0458 | 0.1011 | 0.0844 | 0.1000 | 0.6536 | 6 | 8 | 9 | 10 | 11 | 13 | 15 | 19 | 43 | 0.3560 | 0.58 | 1.966 | 0.8565 | 1342.4 | 217327 | 52700000 | 15600000000 | 0.5872 | 0.1138 | 0.0827 | 0.0402 | 0.0911 | 0.0460 | 0.0905 | 0.0583 | 0.1079 | 0.0708 | 0.1235 | 0.1009 | 0.1307 | 0.1071 | 0.1589 | 0.1225 | 0.1457 | 0.1493 | 0.0689 | 0.3048 | 0.0327 | 0.0279 | 0.0346 | 0.0300 | 0.0335 | 0.0375 | 0.0372 | 0.0451 | 0.0380 | 0.0643 | 0.0515 | 0.0758 | 0.0560 | 0.0781 | 0.0861 | 0.0967 | 0.6304 | 0.5445 | 0.0142 | 0.0053 | 0.0137 | 0.0053 | 0.0132 | 0.0107 | 0.0179 | 0.0165 | 0.0189 | 0.0256 | 0.0344 | 0.0373 | 0.0387 | 0.0453 | 0.0783 | 0.0719 | 0.7708 | 0.7821 | 0.0197 | 0.0239 | 0.0239 | 0.0337 | 0.0322 | 0.0405 | 0.0348 | 0.0594 | 0.7319 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 999 | 759 | | 7014 | 22115 | 261.5 | 51.41 | 152.85 | 246.06 | 199 | 217 | 231 | 244 | 257 | 271 | 286 | 305 | 332 | 0.0572 | 1264 | 0.703 | 157.81 | 44.60 | 2 | 0.0720 | 505 | 0.0008 | 54.08 | 7.368 | 0.1589 | 71002.4 | 20000000 | 5820000000 | 1750000000000 | 0.4542 | 0.2013 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0198 | 0.0018 | 0.0614 | 0.0168 | 0.1165 | 0.0363 | 0.1431 | 0.0312 | 0.1561 | 0.0529 | 0.4986 | 0.8610 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0065 | 0.0007 | 0.0317 | 0.0127 | 0.0548 | 0.0245 | 0.0634 | 0.0171 | 0.0806 | 0.0298 | 0.7622 | 0.9151 | 0.0035 | 0.0142 | 0.0132 | 0.0474 | 0.0307 | 0.0664 | 0.0729 | 0.1232 | 0.1484 | 0.2133 | 0.1756 | 0.1706 | 0.1089 | 0.1611 | 0.1528 | 0.1137 | 0.2941 | 0.0900 | 0.0009 | 0.0021 | 0.0081 | 0.0332 | 0.0865 | 0.1293 | 0.1164 | 0.1320 | 0.4914 | 9 | 11 | 12 | 14 | 18 | 37 | 127 | 301 | 523 | 0.1005 | 52.42 | 4.809 | 0.5431 | 83904.9 | 63400000 | 57600000000 | 60200000000000 | 0.4909 | 0.1549 | 0.1011 | 0.0081 | 0.3100 | 0.0501 | 0.3478 | 0.2536 | 0.1133 | 0.2036 | 0.0800 | 0.1659 | 0.0233 | 0.1438 | 0.0122 | 0.0845 | 0.0067 | 0.0549 | 0.0056 | 0.0355 | 0.0001 | 0.0004 | 0.0009 | 0.0006 | 0.0022 | 0.0018 | 0.0097 | 0.0091 | 0.0460 | 0.0426 | 0.0824 | 0.0794 | 0.0515 | 0.0480 | 0.0790 | 0.0681 | 0.7281 | 0.7501 | 0.0000 | 0.0007 | 0.0015 | 0.0024 | 0.0028 | 0.0041 | 0.0143 | 0.0111 | 0.0528 | 0.0560 | 0.0945 | 0.1016 | 0.0625 | 0.0621 | 0.0883 | 0.0970 | 0.6834 | 0.6651 | 0.0003 | 0.0006 | 0.0019 | 0.0083 | 0.0525 | 0.0906 | 0.0541 | 0.0823 | 0.7093 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 332 | 897 | | 4130 | 6420 | 525.0 | 190.33 | 45.50 | 77.20 | 256 | 314 | 388 | 474 | 542 | 599 | 659 | 716 | 767 | 0.1092 | 701 | 0.638 | 84.10 | 14.14 | 5 | 0.0482 | 199 | 0.0007 | 53.48 | 7.439 | 0.1929 | 311857.0 | 201000000 | 138000000000 | 98300000000000 | 0.3906 | 0.2301 | 0.0000 | 0.0015 | 0.0031 | 0.0011 | 0.0168 | 0.0011 | 0.0291 | 0.0083 | 0.1034 | 0.0496 | 0.1516 | 0.0931 | 0.1309 | 0.0644 | 0.1072 | 0.0966 | 0.4579 | 0.6842 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0018 | 0.0328 | 0.0255 | 0.0470 | 0.0436 | 0.0303 | 0.0252 | 0.0445 | 0.0370 | 0.8418 | 0.8670 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0021 | 0.0167 | 0.0104 | 0.0410 | 0.0494 | 0.0819 | 0.0626 | 0.1335 | 0.0494 | 0.1108 | 0.0745 | 0.1457 | 0.7516 | 0.4643 | 0.0000 | 0.0005 | 0.0005 | 0.0045 | 0.0352 | 0.0587 | 0.0352 | 0.0564 | 0.8090 | 8 | 10 | 13 | 15 | 17 | 22 | 31 | 60 | 119 | 0.0622 | 10.67 | 3.904 | 0.6364 | 8028.7 | 3400000 | 2280000000 | 1870000000000 | 0.5362 | 0.1440 | 0.0369 | 0.0169 | 0.0844 | 0.0226 | 0.1082 | 0.0463 | 0.1504 | 0.0993 | 0.1847 | 0.1366 | 0.1821 | 0.1061 | 0.1372 | 0.1163 | 0.0976 | 0.1558 | 0.0185 | 0.3002 | 0.0017 | 0.0057 | 0.0034 | 0.0076 | 0.0040 | 0.0086 | 0.0115 | 0.0195 | 0.0453 | 0.0437 | 0.0539 | 0.0518 | 0.0441 | 0.0456 | 0.0648 | 0.0699 | 0.7713 | 0.7476 | 0.0007 | 0.0025 | 0.0029 | 0.0016 | 0.0102 | 0.0074 | 0.0154 | 0.0164 | 0.0469 | 0.0402 | 0.0608 | 0.0731 | 0.0490 | 0.0484 | 0.0791 | 0.0649 | 0.7350 | 0.7455 | 0.0006 | 0.0051 | 0.0058 | 0.0135 | 0.0398 | 0.0630 | 0.0424 | 0.0694 | 0.7603 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 791 | 738 | | 2836 | 2758 | 119.5 | 28.32 | 225.10 | 172.38 | 89 | 99 | 105 | 111 | 115 | 121 | 128 | 137 | 155 | 0.1653 | 456 | 0.603 | 236.69 | 51.26 | 1 | 0.2341 | 664 | 0.0036 | 15.13 | 5.972 | 0.2993 | 15085.0 | 2020000 | 291000000 | 45400000000 | 0.4422 | 0.2144 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0021 | 0.0000 | 0.0185 | 0.0042 | 0.0723 | 0.0261 | 0.1083 | 0.0465 | 0.1591 | 0.0519 | 0.1657 | 0.0711 | 0.4736 | 0.7998 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0067 | 0.0011 | 0.0387 | 0.0176 | 0.0627 | 0.0269 | 0.0753 | 0.0298 | 0.0867 | 0.0384 | 0.7285 | 0.8863 | 0.0070 | 0.0054 | 0.0234 | 0.0163 | 0.0422 | 0.0217 | 0.0749 | 0.0761 | 0.1218 | 0.1848 | 0.1124 | 0.1902 | 0.1101 | 0.1196 | 0.1077 | 0.1413 | 0.4005 | 0.2446 | 0.0041 | 0.0033 | 0.0231 | 0.0430 | 0.1017 | 0.1479 | 0.1083 | 0.1380 | 0.4306 | 20 | 53 | 93 | 143 | 203 | 256 | 310 | 368 | 462 | 0.0047 | 47.42 | 6.617 | 0.2813 | 80370.2 | 35100000 | 17400000000 | 9480000000000 | 0.5310 | 0.1251 | 0.0062 | 0.0011 | 0.1040 | 0.0067 | 0.1996 | 0.0540 | 0.2100 | 0.1012 | 0.1580 | 0.1609 | 0.1393 | 0.2014 | 0.1123 | 0.1620 | 0.0499 | 0.1215 | 0.0208 | 0.1912 | 0.0000 | 0.0000 | 0.0007 | 0.0012 | 0.0033 | 0.0024 | 0.0127 | 0.0135 | 0.0560 | 0.0483 | 0.1133 | 0.0889 | 0.0833 | 0.0700 | 0.1227 | 0.0948 | 0.6080 | 0.6810 | 0.0000 | 0.0025 | 0.0010 | 0.0074 | 0.0059 | 0.0086 | 0.0285 | 0.0395 | 0.1050 | 0.1210 | 0.1501 | 0.1444 | 0.0991 | 0.1222 | 0.1511 | 0.1543 | 0.4593 | 0.4000 | 0.0008 | 0.0008 | 0.0032 | 0.0244 | 0.0630 | 0.1198 | 0.1072 | 0.1308 | 0.5500 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 547 | 120 | | 5210 | 7031 | 116.5 | 33.51 | 67.29 | 88.49 | 82 | 90 | 96 | 102 | 109 | 116 | 126 | 140 | 161 | 0.1074 | 755 | 0.962 | 86.27 | 33.84 | 2 | 0.0478 | 249 | 0.0029 | 20.97 | 6.262 | 0.2723 | 14702.5 | 2030000 | 306000000 | 50600000000 | 0.4062 | 0.2387 | 0.0018 | 0.0000 | 0.0032 | 0.0000 | 0.0093 | 0.0009 | 0.0370 | 0.0017 | 0.1025 | 0.0273 | 0.1787 | 0.0577 | 0.1630 | 0.0624 | 0.1798 | 0.0955 | 0.3247 | 0.7545 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0044 | 0.0004 | 0.0154 | 0.0008 | 0.0427 | 0.0160 | 0.0740 | 0.0248 | 0.0717 | 0.0220 | 0.1040 | 0.0419 | 0.6847 | 0.8941 | 0.0019 | 0.0042 | 0.0049 | 0.0166 | 0.0165 | 0.0374 | 0.0525 | 0.0832 | 0.1380 | 0.1933 | 0.1672 | 0.2121 | 0.1263 | 0.0894 | 0.1545 | 0.1538 | 0.3382 | 0.2100 | 0.0039 | 0.0048 | 0.0101 | 0.0400 | 0.0761 | 0.1094 | 0.1104 | 0.1359 | 0.5094 | 12 | 15 | 20 | 26 | 33 | 43 | 64 | 100 | 163 | 0.0295 | 19.01 | 4.722 | 0.5549 | 12357.0 | 4090000 | 1840000000 | 978000000000 | 0.7256 | 0.0616 | 0.0176 | 0.0062 | 0.0821 | 0.0241 | 0.1437 | 0.0469 | 0.1935 | 0.0841 | 0.1686 | 0.1496 | 0.1569 | 0.1695 | 0.0997 | 0.1447 | 0.0982 | 0.1371 | 0.0396 | 0.2378 | 0.0025 | 0.0024 | 0.0050 | 0.0041 | 0.0103 | 0.0111 | 0.0227 | 0.0199 | 0.0900 | 0.0827 | 0.1399 | 0.1253 | 0.0929 | 0.0918 | 0.1312 | 0.1236 | 0.5056 | 0.5392 | 0.0011 | 0.0020 | 0.0092 | 0.0033 | 0.0075 | 0.0139 | 0.0316 | 0.0463 | 0.1086 | 0.1026 | 0.1580 | 0.1794 | 0.1080 | 0.1112 | 0.1356 | 0.1456 | 0.4406 | 0.3958 | 0.0034 | 0.0034 | 0.0112 | 0.0244 | 0.0937 | 0.1541 | 0.0941 | 0.1332 | 0.4824 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 953 | 241 | | 4452 | 16651 | 514.3 | 202.79 | 16.75 | 22.48 | 264 | 314 | 365 | 425 | 496 | 574 | 650 | 721 | 776 | 0.0610 | 1016 | 0.831 | 150.81 | 30.46 | 9 | 0.0806 | 359 | 0.0007 | 46.67 | 7.524 | 0.1977 | 305620.0 | 203000000 | 146000000000 | 112000000000000 | 0.3891 | 0.2375 | 0.0008 | 0.0022 | 0.0000 | 0.0000 | 0.0142 | 0.0022 | 0.0334 | 0.0103 | 0.0943 | 0.0357 | 0.1060 | 0.0600 | 0.1018 | 0.0527 | 0.1277 | 0.0681 | 0.5217 | 0.7688 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0015 | 0.0003 | 0.0036 | 0.0052 | 0.0259 | 0.0196 | 0.0353 | 0.0304 | 0.0230 | 0.0232 | 0.0383 | 0.0312 | 0.8724 | 0.8898 | 0.0000 | 0.0000 | 0.0000 | 0.0044 | 0.0019 | 0.0044 | 0.0045 | 0.0166 | 0.0408 | 0.0376 | 0.0388 | 0.0564 | 0.0323 | 0.0431 | 0.0511 | 0.0818 | 0.8305 | 0.7558 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0262 | 0.0419 | 0.0295 | 0.0409 | 0.8548 | 6 | 7 | 8 | 9 | 11 | 14 | 17 | 22 | 30 | 0.1712 | 0.40 | 1.575 | 0.6158 | 785.9 | 143855 | 50100000 | 21000000000 | 0.6171 | 0.0868 | 0.0605 | 0.0488 | 0.0678 | 0.0590 | 0.0946 | 0.0585 | 0.1398 | 0.0738 | 0.1565 | 0.0814 | 0.1773 | 0.0904 | 0.1603 | 0.1323 | 0.1067 | 0.1903 | 0.0365 | 0.2655 | 0.0178 | 0.0287 | 0.0157 | 0.0319 | 0.0185 | 0.0277 | 0.0267 | 0.0319 | 0.0491 | 0.0406 | 0.0697 | 0.0463 | 0.0717 | 0.0582 | 0.1168 | 0.0921 | 0.6140 | 0.6425 | 0.0160 | 0.0168 | 0.0214 | 0.0291 | 0.0295 | 0.0412 | 0.0447 | 0.0496 | 0.0736 | 0.0814 | 0.0894 | 0.0941 | 0.1054 | 0.1129 | 0.1416 | 0.1313 | 0.4783 | 0.4436 | 0.0152 | 0.0164 | 0.0269 | 0.0290 | 0.0574 | 0.0696 | 0.0884 | 0.1384 | 0.5589 |