High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 396 | 484 | 6705 | 17320 | 296.7 | 54.52 | 188.36 | 215.38 | 229 | 252 | 268 | 281 | 294 | 308 | 323 | 341 | 366 | 0.0651 | 1128 | 1.125 | 100.81 | 34.53 | 1 | 0.0374 | 251 | 0.0007 | 67.59 | 7.448 | 0.1401 | 90991.5 | 28800000 | 9420000000 | 3170000000000 | 0.4266 | 0.2263 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0098 | 0.0006 | 0.0495 | 0.0149 | 0.1217 | 0.0298 | 0.1315 | 0.0281 | 0.1657 | 0.0445 | 0.5202 | 0.8819 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0034 | 0.0005 | 0.0240 | 0.0123 | 0.0580 | 0.0227 | 0.0573 | 0.0162 | 0.0780 | 0.0241 | 0.7791 | 0.9240 | 0.0135 | 0.0226 | 0.0303 | 0.0376 | 0.0359 | 0.1053 | 0.1144 | 0.1805 | 0.1435 | 0.2030 | 0.1973 | 0.1729 | 0.1278 | 0.0977 | 0.1200 | 0.0602 | 0.2175 | 0.1203 | 0.0015 | 0.0031 | 0.0096 | 0.0383 | 0.0887 | 0.1279 | 0.1192 | 0.1440 | 0.4677 | 12 | 16 | 22 | 42 | 95 | 169 | 260 | 362 | 503 | 0.0312 | 34.76 | 5.776 | 0.4635 | 81864.7 | 47300000 | 32600000000 | 25500000000000 | 0.5378 | 0.1169 | 0.0484 | 0.0023 | 0.2080 | 0.0231 | 0.2597 | 0.1353 | 0.1473 | 0.1298 | 0.1053 | 0.1761 | 0.1040 | 0.2018 | 0.0536 | 0.1017 | 0.0523 | 0.0809 | 0.0213 | 0.1490 | 0.0004 | 0.0000 | 0.0012 | 0.0007 | 0.0020 | 0.0011 | 0.0082 | 0.0055 | 0.0496 | 0.0436 | 0.0956 | 0.0812 | 0.0682 | 0.0576 | 0.0952 | 0.0781 | 0.6795 | 0.7322 | 0.0003 | 0.0004 | 0.0026 | 0.0012 | 0.0036 | 0.0043 | 0.0123 | 0.0179 | 0.0625 | 0.0724 | 0.1204 | 0.1323 | 0.0904 | 0.0940 | 0.1169 | 0.1260 | 0.5908 | 0.5516 | 0.0002 | 0.0012 | 0.0024 | 0.0085 | 0.0599 | 0.1074 | 0.0784 | 0.1028 | 0.6392 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 844 | 729 | 5195 | 6746 | 513.2 | 118.34 | 131.41 | 201.76 | 374 | 422 | 455 | 484 | 509 | 533 | 559 | 598 | 663 | 0.1269 | 856 | 1.179 | 136.50 | 52.00 | 4 | 0.0670 | 348 | 0.0006 | 81.67 | 7.590 | 0.1403 | 277409.0 | 157000000 | 93300000000 | 57800000000000 | 0.4641 | 0.1828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0002 | 0.0187 | 0.0015 | 0.0728 | 0.0317 | 0.1260 | 0.0589 | 0.1091 | 0.0502 | 0.1534 | 0.0757 | 0.5108 | 0.7819 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0008 | 0.0387 | 0.0254 | 0.0701 | 0.0404 | 0.0576 | 0.0258 | 0.0831 | 0.0416 | 0.7456 | 0.8661 | 0.0059 | 0.0100 | 0.0118 | 0.0134 | 0.0178 | 0.0334 | 0.0675 | 0.1104 | 0.1349 | 0.1371 | 0.1527 | 0.1605 | 0.0982 | 0.1171 | 0.1396 | 0.1371 | 0.3716 | 0.2809 | 0.0012 | 0.0020 | 0.0083 | 0.0313 | 0.0944 | 0.1583 | 0.1035 | 0.1432 | 0.4578 | 7 | 9 | 11 | 15 | 30 | 63 | 128 | 229 | 416 | 0.1248 | 27.25 | 4.487 | 0.5729 | 57968.2 | 37400000 | 29800000000 | 27700000000000 | 0.6421 | 0.0717 | 0.0374 | 0.0045 | 0.1828 | 0.0269 | 0.3106 | 0.1256 | 0.1806 | 0.1469 | 0.1564 | 0.2096 | 0.0639 | 0.2096 | 0.0419 | 0.1188 | 0.0176 | 0.0953 | 0.0088 | 0.0628 | 0.0000 | 0.0004 | 0.0004 | 0.0024 | 0.0009 | 0.0028 | 0.0121 | 0.0108 | 0.0689 | 0.0667 | 0.1123 | 0.0895 | 0.0671 | 0.0667 | 0.0988 | 0.0927 | 0.6395 | 0.6681 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0028 | 0.0050 | 0.0213 | 0.0292 | 0.0786 | 0.0856 | 0.1296 | 0.1290 | 0.0836 | 0.0862 | 0.1072 | 0.1141 | 0.5758 | 0.5509 | 0.0000 | 0.0010 | 0.0035 | 0.0180 | 0.0721 | 0.1181 | 0.0756 | 0.1086 | 0.6031 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 501 | 504 | 10483 | 29050 | 333.7 | 87.79 | 177.85 | 262.57 | 236 | 272 | 293 | 313 | 331 | 350 | 372 | 400 | 442 | 0.0518 | 1504 | 0.386 | 149.64 | 20.59 | 5 | 0.0405 | 425 | 0.0005 | 88.21 | 7.897 | 0.1404 | 119081.0 | 44900000 | 17800000000 | 7380000000000 | 0.4581 | 0.1796 | 0.0000 | 0.0000 | 0.0012 | 0.0001 | 0.0040 | 0.0003 | 0.0124 | 0.0024 | 0.0524 | 0.0199 | 0.0976 | 0.0409 | 0.1048 | 0.0282 | 0.1371 | 0.0397 | 0.5905 | 0.8683 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0043 | 0.0009 | 0.0218 | 0.0129 | 0.0408 | 0.0249 | 0.0434 | 0.0140 | 0.0546 | 0.0203 | 0.8331 | 0.9269 | 0.0063 | 0.0043 | 0.0058 | 0.0029 | 0.0184 | 0.0200 | 0.0442 | 0.0428 | 0.0738 | 0.1056 | 0.1169 | 0.1469 | 0.1004 | 0.0984 | 0.1145 | 0.1213 | 0.5197 | 0.4579 | 0.0012 | 0.0029 | 0.0078 | 0.0171 | 0.0536 | 0.0699 | 0.0740 | 0.0962 | 0.6774 | 11 | 14 | 18 | 25 | 50 | 97 | 178 | 304 | 548 | 0.0648 | 33.20 | 5.292 | 0.5122 | 100572.0 | 82800000 | 82800000000 | 94100000000000 | 0.3716 | 0.2666 | 0.0296 | 0.0017 | 0.1361 | 0.0083 | 0.2160 | 0.0670 | 0.1652 | 0.1170 | 0.1568 | 0.1755 | 0.1326 | 0.1840 | 0.0774 | 0.1333 | 0.0483 | 0.1272 | 0.0380 | 0.1861 | 0.0001 | 0.0003 | 0.0009 | 0.0003 | 0.0034 | 0.0025 | 0.0112 | 0.0111 | 0.0428 | 0.0397 | 0.0676 | 0.0625 | 0.0535 | 0.0451 | 0.0718 | 0.0631 | 0.7487 | 0.7755 | 0.0005 | 0.0007 | 0.0015 | 0.0023 | 0.0044 | 0.0056 | 0.0156 | 0.0203 | 0.0529 | 0.0545 | 0.0833 | 0.0881 | 0.0667 | 0.0649 | 0.0827 | 0.0819 | 0.6924 | 0.6817 | 0.0002 | 0.0008 | 0.0029 | 0.0164 | 0.0438 | 0.0782 | 0.0630 | 0.0794 | 0.7154 | |||
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 724 | 2796 | 6922 | 1289.3 | 297.81 | 11.57 | 14.75 | 882 | 996 | 1126 | 1218 | 1314 | 1409 | 1473 | 1547 | 1666 | 0.1000 | 692 | 0.449 | 77.06 | 17.03 | 1 | 0.0898 | 251 | 0.0006 | 162.50 | 7.490 | 0.1405 | 1750000.0 | 2480000000 | 3640000000000 | 5.5E+15 | 0.4200 | 0.2151 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0006 | 0.0000 | 0.0150 | 0.0008 | 0.0807 | 0.0218 | 0.1502 | 0.0514 | 0.1120 | 0.0327 | 0.1352 | 0.0510 | 0.5063 | 0.8419 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0004 | 0.0334 | 0.0184 | 0.0621 | 0.0376 | 0.0375 | 0.0192 | 0.0570 | 0.0289 | 0.8086 | 0.8955 | 0.0036 | 0.0000 | 0.0125 | 0.0215 | 0.0179 | 0.0538 | 0.0339 | 0.1075 | 0.1179 | 0.1720 | 0.1732 | 0.2151 | 0.0875 | 0.1183 | 0.1304 | 0.1720 | 0.4232 | 0.1398 | 0.0000 | 0.0000 | 0.0007 | 0.0061 | 0.0509 | 0.1141 | 0.0645 | 0.0971 | 0.6667 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 16 | 0.1442 | 0.50 | 1.438 | 0.5109 | 351.5 | 25544.2 | 2750000 | 377000000 | 0.5711 | 0.1027 | 0.1170 | 0.0291 | 0.1623 | 0.0624 | 0.1857 | 0.0979 | 0.1798 | 0.1155 | 0.1535 | 0.1440 | 0.0892 | 0.1715 | 0.0738 | 0.1552 | 0.0322 | 0.1366 | 0.0066 | 0.0877 | 0.0708 | 0.0240 | 0.0893 | 0.0506 | 0.0777 | 0.0776 | 0.0796 | 0.0886 | 0.0949 | 0.1002 | 0.0888 | 0.1140 | 0.1000 | 0.1166 | 0.1124 | 0.1369 | 0.2864 | 0.2915 | 0.0290 | 0.0090 | 0.0139 | 0.0030 | 0.0189 | 0.0060 | 0.0391 | 0.0571 | 0.1009 | 0.1141 | 0.1072 | 0.1096 | 0.0971 | 0.1096 | 0.1299 | 0.1276 | 0.4641 | 0.4640 | 0.0730 | 0.0589 | 0.0518 | 0.0754 | 0.0761 | 0.0934 | 0.1013 | 0.0879 | 0.3823 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 876 | 4650 | 27974 | 298.2 | 83.39 | 212.92 | 186.19 | 196 | 225 | 246 | 269 | 291 | 315 | 341 | 374 | 413 | 0.0507 | 1418 | 1.135 | 46.75 | 17.00 | 6 | 0.0265 | 123 | 0.0006 | 64.25 | 7.641 | 0.1408 | 95900.4 | 32900000 | 11900000000 | 4530000000000 | 0.4875 | 0.1659 | 0.0004 | 0.0000 | 0.0022 | 0.0008 | 0.0057 | 0.0008 | 0.0284 | 0.0091 | 0.1091 | 0.0467 | 0.1916 | 0.0965 | 0.1414 | 0.0657 | 0.1689 | 0.1033 | 0.3522 | 0.6771 | 0.0000 | 0.0000 | 0.0009 | 0.0007 | 0.0020 | 0.0000 | 0.0128 | 0.0059 | 0.0483 | 0.0320 | 0.0762 | 0.0692 | 0.0556 | 0.0391 | 0.0829 | 0.0608 | 0.7213 | 0.7923 | 0.0017 | 0.0048 | 0.0035 | 0.0095 | 0.0096 | 0.0263 | 0.0192 | 0.0668 | 0.0925 | 0.1265 | 0.1187 | 0.1384 | 0.0855 | 0.1289 | 0.1309 | 0.1480 | 0.5384 | 0.3508 | 0.0014 | 0.0009 | 0.0059 | 0.0237 | 0.0702 | 0.0916 | 0.0766 | 0.0861 | 0.6436 | 27 | 52 | 83 | 117 | 157 | 208 | 270 | 356 | 482 | 0.0050 | 46.50 | 6.695 | 0.3231 | 79998.9 | 40100000 | 24000000000 | 16200000000000 | 0.4940 | 0.1623 | 0.0270 | 0.0010 | 0.1183 | 0.0111 | 0.2093 | 0.0488 | 0.1802 | 0.0945 | 0.1620 | 0.1643 | 0.1329 | 0.2010 | 0.0821 | 0.1517 | 0.0530 | 0.1382 | 0.0352 | 0.1895 | 0.0007 | 0.0001 | 0.0014 | 0.0010 | 0.0042 | 0.0026 | 0.0218 | 0.0137 | 0.0642 | 0.0508 | 0.1052 | 0.0828 | 0.0816 | 0.0668 | 0.1081 | 0.0927 | 0.6129 | 0.6894 | 0.0013 | 0.0016 | 0.0028 | 0.0069 | 0.0105 | 0.0144 | 0.0378 | 0.0507 | 0.0975 | 0.1038 | 0.1384 | 0.1575 | 0.1063 | 0.1060 | 0.1287 | 0.1379 | 0.4767 | 0.4212 | 0.0009 | 0.0024 | 0.0075 | 0.0292 | 0.0795 | 0.1238 | 0.0924 | 0.1217 | 0.5426 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 484 | 784 | 7556 | 23389 | 282.7 | 59.70 | 166.78 | 196.60 | 210 | 231 | 247 | 262 | 276 | 293 | 311 | 334 | 366 | 0.0490 | 1145 | 1.213 | 102.16 | 38.05 | 1 | 0.0335 | 253 | 0.0006 | 75.57 | 7.614 | 0.1408 | 83467.9 | 25700000 | 8220000000 | 2730000000000 | 0.4316 | 0.2191 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0020 | 0.0000 | 0.0170 | 0.0010 | 0.0677 | 0.0158 | 0.1511 | 0.0377 | 0.1521 | 0.0373 | 0.1708 | 0.0609 | 0.4384 | 0.8469 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0056 | 0.0004 | 0.0270 | 0.0106 | 0.0679 | 0.0232 | 0.0670 | 0.0160 | 0.0934 | 0.0265 | 0.7377 | 0.9233 | 0.0044 | 0.0233 | 0.0110 | 0.0233 | 0.0242 | 0.0631 | 0.0696 | 0.1728 | 0.1275 | 0.1960 | 0.1758 | 0.2060 | 0.1231 | 0.1063 | 0.1407 | 0.1296 | 0.3238 | 0.0797 | 0.0012 | 0.0035 | 0.0092 | 0.0372 | 0.0773 | 0.1330 | 0.1108 | 0.1304 | 0.4975 | 13 | 15 | 19 | 28 | 65 | 144 | 233 | 329 | 451 | 0.0382 | 38.04 | 5.638 | 0.4378 | 66466.3 | 34900000 | 21500000000 | 14900000000000 | 0.4729 | 0.1465 | 0.0850 | 0.0014 | 0.2309 | 0.0230 | 0.3225 | 0.1754 | 0.1274 | 0.1961 | 0.0928 | 0.2081 | 0.0531 | 0.1530 | 0.0330 | 0.0985 | 0.0279 | 0.0639 | 0.0274 | 0.0806 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0009 | 0.0009 | 0.0084 | 0.0061 | 0.0473 | 0.0406 | 0.0840 | 0.0716 | 0.0667 | 0.0537 | 0.1009 | 0.0862 | 0.6912 | 0.7406 | 0.0001 | 0.0001 | 0.0013 | 0.0011 | 0.0031 | 0.0056 | 0.0161 | 0.0217 | 0.0677 | 0.0724 | 0.1058 | 0.1268 | 0.0903 | 0.0954 | 0.1290 | 0.1366 | 0.5867 | 0.5403 | 0.0000 | 0.0011 | 0.0013 | 0.0122 | 0.0536 | 0.0968 | 0.0807 | 0.1121 | 0.6423 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1048 | 708 | 5142 | 24738 | 301.9 | 68.07 | 109.84 | 172.01 | 222 | 242 | 260 | 277 | 294 | 311 | 331 | 357 | 392 | 0.0388 | 959 | 0.968 | 116.28 | 25.18 | 1 | 0.0492 | 253 | 0.0006 | 71.96 | 7.550 | 0.1408 | 95756.4 | 31900000 | 11200000000 | 4100000000000 | 0.4570 | 0.1935 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0047 | 0.0000 | 0.0216 | 0.0019 | 0.0748 | 0.0214 | 0.1430 | 0.0387 | 0.1596 | 0.0406 | 0.1790 | 0.0601 | 0.4156 | 0.8373 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0082 | 0.0000 | 0.0378 | 0.0149 | 0.0692 | 0.0253 | 0.0736 | 0.0188 | 0.0862 | 0.0339 | 0.7226 | 0.9070 | 0.0043 | 0.0069 | 0.0096 | 0.0069 | 0.0246 | 0.0138 | 0.0769 | 0.0897 | 0.1143 | 0.1655 | 0.1357 | 0.1483 | 0.1026 | 0.1621 | 0.1303 | 0.1345 | 0.4017 | 0.2724 | 0.0009 | 0.0009 | 0.0082 | 0.0359 | 0.0848 | 0.1107 | 0.1086 | 0.1302 | 0.5199 | 8 | 9 | 10 | 12 | 15 | 23 | 92 | 222 | 376 | 0.2071 | 21.28 | 4.079 | 0.6284 | 41652.0 | 21000000 | 12200000000 | 7930000000000 | 0.5079 | 0.1266 | 0.0955 | 0.0067 | 0.2888 | 0.0516 | 0.2966 | 0.2331 | 0.1382 | 0.1992 | 0.0843 | 0.1815 | 0.0618 | 0.1415 | 0.0247 | 0.0705 | 0.0079 | 0.0494 | 0.0022 | 0.0666 | 0.0000 | 0.0001 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0081 | 0.0081 | 0.0426 | 0.0385 | 0.0742 | 0.0621 | 0.0481 | 0.0470 | 0.0763 | 0.0643 | 0.7492 | 0.7792 | 0.0003 | 0.0005 | 0.0011 | 0.0016 | 0.0032 | 0.0042 | 0.0113 | 0.0130 | 0.0493 | 0.0504 | 0.0852 | 0.0895 | 0.0569 | 0.0606 | 0.0833 | 0.0935 | 0.7095 | 0.6868 | 0.0003 | 0.0007 | 0.0018 | 0.0119 | 0.0426 | 0.0802 | 0.0555 | 0.0798 | 0.7272 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1162 | 503 | 2529 | 2344 | 126.3 | 43.34 | 188.90 | 122.03 | 73 | 88 | 100 | 110 | 122 | 133 | 145 | 162 | 185 | 0.1950 | 457 | 0.720 | 84.38 | 20.03 | 1 | 0.0834 | 211 | 0.0009 | 89.32 | 7.225 | 0.1409 | 17828.9 | 2770000 | 469000000 | 85100000000 | 0.4531 | 0.1879 | 0.0000 | 0.0000 | 0.0045 | 0.0021 | 0.0334 | 0.0032 | 0.0885 | 0.0117 | 0.1554 | 0.0573 | 0.2069 | 0.1183 | 0.1527 | 0.1210 | 0.1509 | 0.1666 | 0.2078 | 0.5199 | 0.0000 | 0.0000 | 0.0006 | 0.0013 | 0.0023 | 0.0018 | 0.0153 | 0.0081 | 0.0512 | 0.0346 | 0.0904 | 0.0606 | 0.0745 | 0.0454 | 0.0944 | 0.0718 | 0.6714 | 0.7764 | 0.0031 | 0.0088 | 0.0077 | 0.0263 | 0.0153 | 0.0351 | 0.0537 | 0.0906 | 0.1503 | 0.1579 | 0.1656 | 0.1813 | 0.1012 | 0.0906 | 0.1518 | 0.1579 | 0.3512 | 0.2515 | 0.0000 | 0.0009 | 0.0043 | 0.0282 | 0.1059 | 0.1443 | 0.1059 | 0.1460 | 0.4646 | 57 | 75 | 104 | 135 | 169 | 201 | 239 | 281 | 355 | 0.0049 | 19.35 | 5.900 | 0.3617 | 50569.7 | 17000000 | 6670000000 | 2960000000000 | 0.5121 | 0.1476 | 0.0119 | 0.0010 | 0.0889 | 0.0089 | 0.1976 | 0.0207 | 0.1621 | 0.0720 | 0.1581 | 0.1519 | 0.1561 | 0.2002 | 0.0870 | 0.1322 | 0.0870 | 0.1686 | 0.0514 | 0.2446 | 0.0000 | 0.0006 | 0.0008 | 0.0006 | 0.0093 | 0.0025 | 0.0202 | 0.0153 | 0.0644 | 0.0567 | 0.1149 | 0.0943 | 0.0901 | 0.0732 | 0.1335 | 0.1115 | 0.5668 | 0.6452 | 0.0013 | 0.0090 | 0.0064 | 0.0162 | 0.0153 | 0.0252 | 0.0435 | 0.0629 | 0.1228 | 0.1457 | 0.1662 | 0.1853 | 0.1368 | 0.1097 | 0.1675 | 0.1583 | 0.3402 | 0.2878 | 0.0000 | 0.0019 | 0.0135 | 0.0348 | 0.0890 | 0.1277 | 0.1180 | 0.1750 | 0.4400 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 211 | 348 | 4562 | 14662 | 292.1 | 59.07 | 135.81 | 209.30 | 220 | 241 | 258 | 274 | 289 | 304 | 320 | 340 | 367 | 0.0645 | 945 | 0.932 | 136.85 | 50.12 | 1 | 0.0855 | 390 | 0.0007 | 74.36 | 7.435 | 0.1412 | 88808.4 | 28100000 | 9250000000 | 3170000000000 | 0.4402 | 0.2161 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0029 | 0.0000 | 0.0167 | 0.0014 | 0.0694 | 0.0171 | 0.1478 | 0.0364 | 0.1491 | 0.0316 | 0.1825 | 0.0583 | 0.4299 | 0.8552 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0018 | 0.0000 | 0.0071 | 0.0004 | 0.0325 | 0.0141 | 0.0723 | 0.0270 | 0.0621 | 0.0175 | 0.0948 | 0.0314 | 0.7283 | 0.9096 | 0.0085 | 0.0305 | 0.0142 | 0.0534 | 0.0355 | 0.0763 | 0.1050 | 0.1374 | 0.1475 | 0.1527 | 0.2014 | 0.1450 | 0.1078 | 0.1145 | 0.1362 | 0.1069 | 0.2440 | 0.1832 | 0.0009 | 0.0045 | 0.0095 | 0.0345 | 0.0971 | 0.1324 | 0.1261 | 0.1515 | 0.4435 | 11 | 12 | 14 | 17 | 22 | 47 | 116 | 250 | 458 | 0.0764 | 33.39 | 4.749 | 0.5335 | 62246.8 | 39200000 | 28700000000 | 23200000000000 | 0.5235 | 0.1167 | 0.0898 | 0.0014 | 0.2511 | 0.0304 | 0.2735 | 0.1824 | 0.1276 | 0.2041 | 0.1024 | 0.2020 | 0.0589 | 0.1399 | 0.0449 | 0.0878 | 0.0337 | 0.0662 | 0.0182 | 0.0858 | 0.0002 | 0.0002 | 0.0002 | 0.0002 | 0.0026 | 0.0024 | 0.0088 | 0.0086 | 0.0505 | 0.0448 | 0.0827 | 0.0772 | 0.0569 | 0.0558 | 0.0882 | 0.0792 | 0.7098 | 0.7318 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0094 | 0.0111 | 0.0555 | 0.0599 | 0.0916 | 0.1008 | 0.0699 | 0.0806 | 0.1010 | 0.1079 | 0.6706 | 0.6378 | 0.0002 | 0.0015 | 0.0015 | 0.0077 | 0.0503 | 0.0907 | 0.0609 | 0.0912 | 0.6961 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1039 | 222 | 8267 | 22106 | 288.0 | 59.05 | 151.11 | 185.59 | 216 | 238 | 254 | 269 | 282 | 298 | 314 | 336 | 366 | 0.0470 | 1038 | 1.207 | 123.17 | 44.29 | 1 | 0.0368 | 304 | 0.0006 | 72.43 | 7.591 | 0.1414 | 86440.9 | 27000000 | 8770000000 | 2960000000000 | 0.4619 | 0.1920 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0001 | 0.0163 | 0.0014 | 0.0611 | 0.0158 | 0.1248 | 0.0327 | 0.1394 | 0.0332 | 0.1689 | 0.0503 | 0.4834 | 0.8666 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0049 | 0.0000 | 0.0290 | 0.0113 | 0.0560 | 0.0195 | 0.0638 | 0.0161 | 0.0864 | 0.0281 | 0.7592 | 0.9250 | 0.0044 | 0.0122 | 0.0059 | 0.0122 | 0.0344 | 0.0459 | 0.0659 | 0.0979 | 0.1553 | 0.2049 | 0.1919 | 0.2141 | 0.1114 | 0.1070 | 0.1495 | 0.1346 | 0.2813 | 0.1713 | 0.0026 | 0.0018 | 0.0099 | 0.0342 | 0.0861 | 0.1315 | 0.1084 | 0.1380 | 0.4874 | 12 | 15 | 17 | 24 | 55 | 118 | 196 | 294 | 424 | 0.0394 | 36.87 | 5.514 | 0.4378 | 57275.2 | 29300000 | 17900000000 | 12400000000000 | 0.4786 | 0.1762 | 0.0641 | 0.0023 | 0.1929 | 0.0255 | 0.2734 | 0.1224 | 0.1781 | 0.1756 | 0.1168 | 0.1948 | 0.0851 | 0.1693 | 0.0556 | 0.1219 | 0.0221 | 0.0910 | 0.0119 | 0.0973 | 0.0001 | 0.0000 | 0.0005 | 0.0005 | 0.0019 | 0.0008 | 0.0100 | 0.0091 | 0.0516 | 0.0439 | 0.0899 | 0.0793 | 0.0692 | 0.0605 | 0.0927 | 0.0806 | 0.6841 | 0.7253 | 0.0014 | 0.0005 | 0.0020 | 0.0011 | 0.0047 | 0.0047 | 0.0137 | 0.0179 | 0.0676 | 0.0722 | 0.1069 | 0.1192 | 0.0847 | 0.0896 | 0.1139 | 0.1168 | 0.6051 | 0.5781 | 0.0001 | 0.0011 | 0.0038 | 0.0118 | 0.0592 | 0.1021 | 0.0731 | 0.1069 | 0.6419 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1089 | 808 | 9170 | 24605 | 276.9 | 78.28 | 148.86 | 243.52 | 189 | 217 | 236 | 252 | 269 | 287 | 308 | 335 | 379 | 0.0478 | 1177 | 0.975 | 178.47 | 49.01 | 3 | 0.0484 | 444 | 0.0005 | 83.21 | 7.806 | 0.1414 | 82817.9 | 26600000 | 9120000000 | 3340000000000 | 0.3821 | 0.2526 | 0.0006 | 0.0000 | 0.0006 | 0.0003 | 0.0050 | 0.0006 | 0.0193 | 0.0027 | 0.0640 | 0.0215 | 0.1201 | 0.0404 | 0.1246 | 0.0400 | 0.1755 | 0.0620 | 0.4903 | 0.8326 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0081 | 0.0007 | 0.0235 | 0.0104 | 0.0451 | 0.0203 | 0.0512 | 0.0147 | 0.0759 | 0.0249 | 0.7939 | 0.9289 | 0.0042 | 0.0025 | 0.0052 | 0.0076 | 0.0157 | 0.0290 | 0.0408 | 0.0718 | 0.0963 | 0.1272 | 0.1387 | 0.1348 | 0.0994 | 0.1083 | 0.1251 | 0.1486 | 0.4746 | 0.3703 | 0.0014 | 0.0038 | 0.0107 | 0.0227 | 0.0568 | 0.0940 | 0.0838 | 0.1095 | 0.6172 | 10 | 13 | 15 | 19 | 31 | 61 | 125 | 239 | 462 | 0.0836 | 33.10 | 4.848 | 0.5636 | 81459.4 | 66300000 | 65000000000 | 71600000000000 | 0.3987 | 0.2387 | 0.0508 | 0.0023 | 0.1457 | 0.0182 | 0.2453 | 0.0872 | 0.1798 | 0.1196 | 0.1631 | 0.1870 | 0.1009 | 0.1877 | 0.0602 | 0.1413 | 0.0328 | 0.1066 | 0.0214 | 0.1501 | 0.0005 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0019 | 0.0118 | 0.0111 | 0.0408 | 0.0392 | 0.0780 | 0.0652 | 0.0537 | 0.0500 | 0.0809 | 0.0683 | 0.7301 | 0.7639 | 0.0008 | 0.0004 | 0.0010 | 0.0022 | 0.0038 | 0.0053 | 0.0155 | 0.0224 | 0.0573 | 0.0634 | 0.0994 | 0.0936 | 0.0692 | 0.0729 | 0.0878 | 0.0951 | 0.6653 | 0.6447 | 0.0003 | 0.0010 | 0.0025 | 0.0126 | 0.0505 | 0.0841 | 0.0681 | 0.0859 | 0.6949 | |||
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 472 | 365 | 10152 | 16333 | 306.6 | 57.54 | 224.30 | 196.37 | 237 | 256 | 271 | 285 | 301 | 317 | 336 | 357 | 386 | 0.0678 | 1107 | 0.822 | 136.62 | 44.05 | 1 | 0.0396 | 402 | 0.0006 | 77.66 | 7.651 | 0.1416 | 97320.9 | 31900000 | 10800000000 | 3780000000000 | 0.4559 | 0.2016 | 0.0007 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0001 | 0.0147 | 0.0006 | 0.0559 | 0.0105 | 0.1218 | 0.0272 | 0.1337 | 0.0260 | 0.1584 | 0.0428 | 0.5103 | 0.8928 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0036 | 0.0001 | 0.0257 | 0.0079 | 0.0578 | 0.0184 | 0.0582 | 0.0109 | 0.0841 | 0.0197 | 0.7693 | 0.9430 | 0.0025 | 0.0159 | 0.0101 | 0.0518 | 0.0297 | 0.0876 | 0.0802 | 0.2072 | 0.1723 | 0.1952 | 0.1799 | 0.1474 | 0.1187 | 0.1036 | 0.1503 | 0.0558 | 0.2563 | 0.1355 | 0.0008 | 0.0025 | 0.0127 | 0.0317 | 0.0909 | 0.1254 | 0.1094 | 0.1379 | 0.4885 | 22 | 46 | 83 | 125 | 173 | 229 | 295 | 376 | 500 | 0.0068 | 69.26 | 6.886 | 0.2834 | 88869.9 | 46400000 | 29000000000 | 20500000000000 | 0.5451 | 0.1262 | 0.0275 | 0.0020 | 0.1405 | 0.0066 | 0.2540 | 0.0553 | 0.1753 | 0.1106 | 0.1531 | 0.1890 | 0.1086 | 0.2034 | 0.0715 | 0.1379 | 0.0376 | 0.1361 | 0.0319 | 0.1591 | 0.0004 | 0.0006 | 0.0004 | 0.0007 | 0.0035 | 0.0023 | 0.0163 | 0.0094 | 0.0680 | 0.0540 | 0.1119 | 0.0867 | 0.0864 | 0.0698 | 0.1192 | 0.1056 | 0.5940 | 0.6708 | 0.0002 | 0.0013 | 0.0020 | 0.0036 | 0.0087 | 0.0107 | 0.0296 | 0.0330 | 0.1018 | 0.1162 | 0.1498 | 0.1759 | 0.1073 | 0.1119 | 0.1433 | 0.1478 | 0.4572 | 0.3996 | 0.0004 | 0.0016 | 0.0045 | 0.0181 | 0.0879 | 0.1310 | 0.0994 | 0.1385 | 0.5186 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | |||
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 766 | 509 | 21316 | 24107 | 152.8 | 47.18 | 163.56 | 211.64 | 92 | 112 | 127 | 140 | 153 | 165 | 177 | 192 | 213 | 0.1036 | 2498 | 0.827 | 32.25 | 8.06 | 7 | 0.0040 | 86 | 0.0005 | 77.74 | 7.966 | 0.1418 | 25560.0 | 4600000 | 879000000 | 178000000000 | 0.4877 | 0.1525 | 0.0009 | 0.0000 | 0.0037 | 0.0002 | 0.0149 | 0.0010 | 0.0428 | 0.0072 | 0.1047 | 0.0330 | 0.1809 | 0.0736 | 0.1588 | 0.0762 | 0.1780 | 0.0986 | 0.3152 | 0.7103 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0020 | 0.0004 | 0.0097 | 0.0036 | 0.0325 | 0.0180 | 0.0642 | 0.0375 | 0.0588 | 0.0332 | 0.0797 | 0.0428 | 0.7519 | 0.8643 | 0.0029 | 0.0050 | 0.0051 | 0.0208 | 0.0156 | 0.0337 | 0.0478 | 0.0972 | 0.1088 | 0.1622 | 0.1603 | 0.2009 | 0.1202 | 0.1275 | 0.1473 | 0.1314 | 0.3919 | 0.2212 | 0.0008 | 0.0017 | 0.0048 | 0.0220 | 0.0553 | 0.0994 | 0.0941 | 0.1118 | 0.6100 | 16 | 20 | 29 | 40 | 58 | 89 | 164 | 305 | 506 | 0.0680 | 12.41 | 4.640 | 0.6115 | 71539.6 | 42800000 | 29400000000 | 22000000000000 | 0.5538 | 0.1336 | 0.0351 | 0.0046 | 0.1280 | 0.0167 | 0.2120 | 0.0578 | 0.1783 | 0.0940 | 0.1652 | 0.1624 | 0.1225 | 0.1970 | 0.0736 | 0.1265 | 0.0427 | 0.1262 | 0.0427 | 0.2147 | 0.0004 | 0.0008 | 0.0014 | 0.0014 | 0.0027 | 0.0031 | 0.0150 | 0.0104 | 0.0386 | 0.0411 | 0.0622 | 0.0561 | 0.0522 | 0.0433 | 0.0703 | 0.0687 | 0.7572 | 0.7752 | 0.0009 | 0.0010 | 0.0030 | 0.0044 | 0.0068 | 0.0054 | 0.0149 | 0.0123 | 0.0452 | 0.0465 | 0.0647 | 0.0707 | 0.0588 | 0.0625 | 0.0807 | 0.0936 | 0.7250 | 0.7037 | 0.0003 | 0.0026 | 0.0046 | 0.0144 | 0.0427 | 0.0684 | 0.0512 | 0.0708 | 0.7451 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 855 | 295 | 10991 | 23655 | 262.5 | 76.92 | 158.35 | 201.26 | 177 | 198 | 216 | 232 | 250 | 269 | 292 | 321 | 366 | 0.0567 | 1341 | 1.156 | 118.61 | 44.10 | 2 | 0.0278 | 305 | 0.0005 | 81.23 | 7.822 | 0.1418 | 74835.2 | 23200000 | 7750000000 | 2800000000000 | 0.4804 | 0.1627 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0071 | 0.0009 | 0.0294 | 0.0045 | 0.0907 | 0.0256 | 0.1763 | 0.0635 | 0.1516 | 0.0562 | 0.1834 | 0.0790 | 0.3603 | 0.7703 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0004 | 0.0117 | 0.0023 | 0.0349 | 0.0146 | 0.0759 | 0.0366 | 0.0625 | 0.0262 | 0.0909 | 0.0372 | 0.7224 | 0.8828 | 0.0004 | 0.0038 | 0.0059 | 0.0084 | 0.0143 | 0.0188 | 0.0412 | 0.0619 | 0.1017 | 0.1210 | 0.1509 | 0.1642 | 0.1076 | 0.1098 | 0.1366 | 0.1407 | 0.4414 | 0.3715 | 0.0008 | 0.0036 | 0.0096 | 0.0273 | 0.0644 | 0.1087 | 0.0818 | 0.1101 | 0.5937 | 10 | 12 | 15 | 20 | 43 | 109 | 209 | 323 | 476 | 0.0700 | 31.05 | 5.286 | 0.4973 | 65578.9 | 35100000 | 21700000000 | 15000000000000 | 0.5467 | 0.1326 | 0.0587 | 0.0020 | 0.2015 | 0.0205 | 0.3009 | 0.1523 | 0.1628 | 0.1523 | 0.1274 | 0.1764 | 0.0861 | 0.1946 | 0.0327 | 0.1099 | 0.0254 | 0.0900 | 0.0047 | 0.1020 | 0.0002 | 0.0002 | 0.0004 | 0.0001 | 0.0015 | 0.0005 | 0.0054 | 0.0054 | 0.0421 | 0.0359 | 0.0826 | 0.0761 | 0.0556 | 0.0480 | 0.0768 | 0.0648 | 0.7354 | 0.7690 | 0.0001 | 0.0000 | 0.0009 | 0.0009 | 0.0029 | 0.0031 | 0.0107 | 0.0130 | 0.0544 | 0.0570 | 0.1019 | 0.1180 | 0.0672 | 0.0698 | 0.0986 | 0.1004 | 0.6631 | 0.6377 | 0.0001 | 0.0002 | 0.0014 | 0.0079 | 0.0478 | 0.0936 | 0.0584 | 0.0901 | 0.7003 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 921 | 862 | 6477 | 15065 | 403.9 | 109.37 | 121.63 | 165.75 | 277 | 309 | 337 | 363 | 389 | 418 | 449 | 490 | 551 | 0.0525 | 791 | 0.968 | 109.17 | 33.06 | 1 | 0.0426 | 276 | 0.0006 | 77.54 | 7.589 | 0.1419 | 175073.0 | 81300000 | 40400000000 | 21300000000000 | 0.4463 | 0.2101 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0155 | 0.0004 | 0.0348 | 0.0028 | 0.1035 | 0.0244 | 0.1860 | 0.0559 | 0.1699 | 0.0627 | 0.1719 | 0.0842 | 0.3162 | 0.7696 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0023 | 0.0002 | 0.0093 | 0.0018 | 0.0399 | 0.0117 | 0.0837 | 0.0302 | 0.0747 | 0.0280 | 0.0983 | 0.0411 | 0.6910 | 0.8871 | 0.0029 | 0.0053 | 0.0174 | 0.0106 | 0.0101 | 0.0301 | 0.0702 | 0.0816 | 0.1259 | 0.1667 | 0.1802 | 0.1613 | 0.0948 | 0.1241 | 0.1324 | 0.1436 | 0.3661 | 0.2766 | 0.0003 | 0.0010 | 0.0055 | 0.0331 | 0.0776 | 0.1479 | 0.1117 | 0.1317 | 0.4912 | 7 | 9 | 13 | 25 | 47 | 84 | 137 | 215 | 339 | 0.0659 | 15.12 | 4.966 | 0.5541 | 42265.8 | 22000000 | 14400000000 | 10800000000000 | 0.3883 | 0.2650 | 0.0173 | 0.0015 | 0.0965 | 0.0090 | 0.2033 | 0.0324 | 0.1790 | 0.0799 | 0.1931 | 0.1735 | 0.1468 | 0.2123 | 0.0950 | 0.1508 | 0.0502 | 0.1388 | 0.0188 | 0.2017 | 0.0002 | 0.0002 | 0.0013 | 0.0011 | 0.0020 | 0.0012 | 0.0089 | 0.0089 | 0.0379 | 0.0318 | 0.0609 | 0.0533 | 0.0508 | 0.0440 | 0.0713 | 0.0640 | 0.7668 | 0.7956 | 0.0000 | 0.0003 | 0.0007 | 0.0005 | 0.0044 | 0.0032 | 0.0125 | 0.0119 | 0.0504 | 0.0631 | 0.0900 | 0.0998 | 0.0666 | 0.0700 | 0.0928 | 0.1054 | 0.6826 | 0.6458 | 0.0002 | 0.0002 | 0.0026 | 0.0098 | 0.0427 | 0.0786 | 0.0642 | 0.0823 | 0.7195 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1189 | 718 | 4088 | 19318 | 453.0 | 106.58 | 96.23 | 99.59 | 325 | 357 | 386 | 412 | 441 | 469 | 504 | 546 | 607 | 0.0500 | 965 | 1.115 | 111.23 | 32.65 | 1 | 0.0624 | 255 | 0.0007 | 67.51 | 7.409 | 0.1424 | 216555.0 | 109000000 | 57400000000 | 31500000000000 | 0.4176 | 0.2368 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0042 | 0.0003 | 0.0275 | 0.0040 | 0.0803 | 0.0242 | 0.1695 | 0.0594 | 0.1357 | 0.0548 | 0.1682 | 0.0698 | 0.4134 | 0.7875 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0100 | 0.0017 | 0.0344 | 0.0160 | 0.0821 | 0.0397 | 0.0581 | 0.0242 | 0.0865 | 0.0410 | 0.7264 | 0.8774 | 0.0012 | 0.0071 | 0.0084 | 0.0000 | 0.0096 | 0.0249 | 0.0646 | 0.1068 | 0.0969 | 0.1459 | 0.1352 | 0.1851 | 0.1172 | 0.1281 | 0.1148 | 0.1637 | 0.4522 | 0.2384 | 0.0016 | 0.0043 | 0.0070 | 0.0290 | 0.0774 | 0.1198 | 0.0956 | 0.1263 | 0.5390 | 8 | 11 | 16 | 33 | 63 | 99 | 134 | 174 | 230 | 0.0320 | 16.16 | 5.428 | 0.4394 | 19177.9 | 5220000 | 1780000000 | 719000000000 | 0.4849 | 0.1488 | 0.0329 | 0.0012 | 0.1667 | 0.0102 | 0.2528 | 0.0730 | 0.1924 | 0.1400 | 0.1450 | 0.1900 | 0.1015 | 0.2083 | 0.0551 | 0.1299 | 0.0343 | 0.1220 | 0.0193 | 0.1254 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0020 | 0.0012 | 0.0104 | 0.0077 | 0.0520 | 0.0427 | 0.0878 | 0.0780 | 0.0668 | 0.0541 | 0.0945 | 0.0813 | 0.6857 | 0.7349 | 0.0007 | 0.0007 | 0.0022 | 0.0028 | 0.0048 | 0.0102 | 0.0188 | 0.0254 | 0.0667 | 0.0816 | 0.1172 | 0.1331 | 0.0893 | 0.0932 | 0.1224 | 0.1264 | 0.5778 | 0.5265 | 0.0004 | 0.0004 | 0.0035 | 0.0151 | 0.0545 | 0.1053 | 0.0729 | 0.1062 | 0.6416 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 571 | 922 | 4617 | 8322 | 491.0 | 95.75 | 198.40 | 274.48 | 372 | 405 | 431 | 459 | 485 | 511 | 541 | 573 | 621 | 0.0908 | 756 | 1.217 | 121.30 | 48.70 | 1 | 0.0682 | 315 | 0.0006 | 68.44 | 7.576 | 0.1426 | 250279.0 | 132000000 | 72100000000 | 40600000000000 | 0.4178 | 0.2313 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0025 | 0.0586 | 0.0169 | 0.1189 | 0.0373 | 0.1287 | 0.0263 | 0.1587 | 0.0443 | 0.5217 | 0.8725 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0064 | 0.0011 | 0.0309 | 0.0133 | 0.0554 | 0.0279 | 0.0492 | 0.0168 | 0.0717 | 0.0251 | 0.7855 | 0.9157 | 0.0040 | 0.0000 | 0.0081 | 0.0000 | 0.0256 | 0.0000 | 0.0823 | 0.0000 | 0.1107 | 0.0000 | 0.1741 | 0.0000 | 0.1039 | 0.0000 | 0.1323 | 0.0000 | 0.3590 | 0.0000 | 0.0005 | 0.0023 | 0.0059 | 0.0244 | 0.0765 | 0.1199 | 0.0851 | 0.1231 | 0.5624 | 15 | 20 | 25 | 38 | 68 | 118 | 188 | 348 | 633 | 0.0340 | 31.16 | 5.359 | 0.5201 | 114691.0 | 92700000 | 87100000000 | 90400000000000 | 0.3987 | 0.2243 | 0.0214 | 0.0007 | 0.1193 | 0.0152 | 0.2370 | 0.0550 | 0.1330 | 0.0774 | 0.1361 | 0.1527 | 0.1055 | 0.2069 | 0.0826 | 0.1122 | 0.0841 | 0.1165 | 0.0810 | 0.2634 | 0.0004 | 0.0003 | 0.0029 | 0.0015 | 0.0022 | 0.0021 | 0.0122 | 0.0114 | 0.0561 | 0.0418 | 0.0820 | 0.0749 | 0.0557 | 0.0523 | 0.0805 | 0.0737 | 0.7080 | 0.7419 | 0.0005 | 0.0000 | 0.0014 | 0.0010 | 0.0056 | 0.0031 | 0.0118 | 0.0118 | 0.0592 | 0.0536 | 0.0870 | 0.1050 | 0.0602 | 0.0551 | 0.0827 | 0.0881 | 0.6916 | 0.6823 | 0.0008 | 0.0017 | 0.0033 | 0.0124 | 0.0541 | 0.0880 | 0.0570 | 0.0843 | 0.6985 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 318 | 872 | 12186 | 25790 | 350.1 | 84.35 | 180.74 | 231.33 | 250 | 278 | 300 | 319 | 340 | 362 | 386 | 419 | 463 | 0.0459 | 1185 | 1.241 | 90.52 | 37.58 | 1 | 0.0197 | 240 | 0.0006 | 79.84 | 7.705 | 0.1428 | 129698.0 | 50800000 | 21000000000 | 9160000000000 | 0.4637 | 0.1985 | 0.0008 | 0.0000 | 0.0050 | 0.0002 | 0.0093 | 0.0019 | 0.0269 | 0.0039 | 0.0810 | 0.0184 | 0.1487 | 0.0417 | 0.1625 | 0.0489 | 0.1712 | 0.0732 | 0.3947 | 0.8118 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0020 | 0.0001 | 0.0091 | 0.0003 | 0.0330 | 0.0101 | 0.0662 | 0.0219 | 0.0745 | 0.0199 | 0.0941 | 0.0344 | 0.7203 | 0.9133 | 0.0050 | 0.0088 | 0.0083 | 0.0113 | 0.0190 | 0.0479 | 0.0690 | 0.1614 | 0.1467 | 0.1589 | 0.1789 | 0.2320 | 0.1149 | 0.1236 | 0.1471 | 0.1097 | 0.3112 | 0.1463 | 0.0009 | 0.0031 | 0.0086 | 0.0355 | 0.0810 | 0.1311 | 0.1118 | 0.1336 | 0.4943 | 10 | 15 | 25 | 45 | 80 | 130 | 204 | 324 | 514 | 0.0440 | 29.42 | 5.543 | 0.4890 | 86176.2 | 59000000 | 49700000000 | 48200000000000 | 0.4861 | 0.1546 | 0.0520 | 0.0023 | 0.1701 | 0.0129 | 0.2665 | 0.0966 | 0.1459 | 0.1378 | 0.1201 | 0.1935 | 0.1172 | 0.1886 | 0.0605 | 0.1155 | 0.0372 | 0.1007 | 0.0305 | 0.1521 | 0.0003 | 0.0004 | 0.0012 | 0.0006 | 0.0023 | 0.0023 | 0.0133 | 0.0093 | 0.0591 | 0.0486 | 0.0997 | 0.0816 | 0.0694 | 0.0558 | 0.1037 | 0.0915 | 0.6512 | 0.7099 | 0.0005 | 0.0003 | 0.0007 | 0.0026 | 0.0046 | 0.0032 | 0.0156 | 0.0218 | 0.0784 | 0.0855 | 0.1293 | 0.1333 | 0.0752 | 0.0852 | 0.1163 | 0.1277 | 0.5793 | 0.5404 | 0.0006 | 0.0014 | 0.0033 | 0.0161 | 0.0656 | 0.1205 | 0.0715 | 0.1126 | 0.6084 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 840 | 632 | 7599 | 25331 | 439.9 | 83.79 | 168.72 | 276.45 | 340 | 369 | 390 | 410 | 429 | 450 | 476 | 508 | 555 | 0.0492 | 1247 | 1.002 | 122.50 | 43.46 | 1 | 0.0425 | 323 | 0.0006 | 77.97 | 7.638 | 0.1430 | 200554.0 | 94700000 | 46300000000 | 23400000000000 | 0.4550 | 0.1957 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0026 | 0.0000 | 0.0094 | 0.0007 | 0.0535 | 0.0144 | 0.1165 | 0.0319 | 0.1324 | 0.0357 | 0.1602 | 0.0471 | 0.5253 | 0.8703 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0278 | 0.0111 | 0.0578 | 0.0182 | 0.0625 | 0.0137 | 0.0881 | 0.0211 | 0.7604 | 0.9358 | 0.0025 | 0.0077 | 0.0101 | 0.0193 | 0.0126 | 0.0386 | 0.0666 | 0.2278 | 0.1265 | 0.2162 | 0.1678 | 0.2355 | 0.1273 | 0.1042 | 0.1669 | 0.0965 | 0.3196 | 0.0541 | 0.0012 | 0.0026 | 0.0096 | 0.0417 | 0.0858 | 0.1214 | 0.1033 | 0.1219 | 0.5125 | 6 | 7 | 9 | 11 | 16 | 45 | 143 | 328 | 583 | 0.1315 | 51.22 | 4.587 | 0.5228 | 104886.0 | 87500000 | 85800000000 | 94300000000000 | 0.5042 | 0.1314 | 0.1174 | 0.0045 | 0.3070 | 0.0508 | 0.2798 | 0.2324 | 0.1277 | 0.2165 | 0.1108 | 0.1884 | 0.0404 | 0.1303 | 0.0113 | 0.0944 | 0.0038 | 0.0477 | 0.0019 | 0.0350 | 0.0001 | 0.0001 | 0.0012 | 0.0004 | 0.0026 | 0.0011 | 0.0093 | 0.0084 | 0.0522 | 0.0465 | 0.0772 | 0.0740 | 0.0532 | 0.0513 | 0.0848 | 0.0734 | 0.7194 | 0.7448 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0021 | 0.0027 | 0.0093 | 0.0091 | 0.0560 | 0.0627 | 0.0918 | 0.1001 | 0.0656 | 0.0705 | 0.1066 | 0.1206 | 0.6678 | 0.6332 | 0.0003 | 0.0015 | 0.0032 | 0.0089 | 0.0529 | 0.0819 | 0.0600 | 0.0898 | 0.7015 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1272 | 883 | 1150 | 8995 | 239.8 | 65.75 | 123.62 | 67.46 | 158 | 173 | 191 | 209 | 232 | 258 | 286 | 306 | 330 | 0.0845 | 760 | 0.982 | 95.52 | 25.18 | 3 | 0.2000 | 230 | 0.0013 | 67.56 | 6.741 | 0.1434 | 61808.3 | 17000000 | 4910000000 | 1480000000000 | 0.4669 | 0.1629 | 0.0043 | 0.0010 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0469 | 0.0068 | 0.1919 | 0.0476 | 0.2751 | 0.1322 | 0.1663 | 0.0787 | 0.1215 | 0.1351 | 0.1919 | 0.5986 | 0.0013 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0150 | 0.0045 | 0.0614 | 0.0303 | 0.0852 | 0.1025 | 0.0576 | 0.0357 | 0.0827 | 0.0677 | 0.6967 | 0.7585 | 0.0000 | 0.0108 | 0.0000 | 0.0323 | 0.0000 | 0.0538 | 0.0274 | 0.1720 | 0.1337 | 0.1398 | 0.1125 | 0.1613 | 0.1155 | 0.1720 | 0.1763 | 0.1075 | 0.4347 | 0.1505 | 0.0000 | 0.0000 | 0.0019 | 0.0242 | 0.0576 | 0.1022 | 0.0762 | 0.0929 | 0.6450 | 49 | 64 | 78 | 92 | 110 | 130 | 153 | 178 | 216 | 0.0036 | 19.57 | 6.129 | 0.3167 | 19833.3 | 3880000 | 886000000 | 230000000000 | 0.5219 | 0.1301 | 0.0186 | 0.0026 | 0.0971 | 0.0077 | 0.1631 | 0.0208 | 0.1817 | 0.0612 | 0.1719 | 0.1229 | 0.1524 | 0.1718 | 0.1115 | 0.1593 | 0.0678 | 0.1860 | 0.0358 | 0.2677 | 0.0012 | 0.0012 | 0.0034 | 0.0023 | 0.0078 | 0.0055 | 0.0254 | 0.0158 | 0.0730 | 0.0453 | 0.1045 | 0.0772 | 0.1015 | 0.0721 | 0.1389 | 0.1101 | 0.5443 | 0.6705 | 0.0011 | 0.0082 | 0.0102 | 0.0169 | 0.0186 | 0.0416 | 0.0629 | 0.0914 | 0.1265 | 0.1422 | 0.1757 | 0.1792 | 0.1409 | 0.1555 | 0.1452 | 0.1247 | 0.3188 | 0.2402 | 0.0018 | 0.0043 | 0.0128 | 0.0337 | 0.0856 | 0.1573 | 0.1206 | 0.1418 | 0.4421 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 619 | 317 | 7410 | 29983 | 364.7 | 86.29 | 152.06 | 265.97 | 260 | 289 | 313 | 336 | 358 | 380 | 405 | 434 | 477 | 0.0351 | 1051 | 1.206 | 108.37 | 43.84 | 1 | 0.0379 | 281 | 0.0006 | 87.06 | 7.645 | 0.1436 | 140416.0 | 57000000 | 24300000000 | 10900000000000 | 0.4464 | 0.2073 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0086 | 0.0001 | 0.0271 | 0.0018 | 0.0873 | 0.0187 | 0.1534 | 0.0482 | 0.1532 | 0.0439 | 0.1846 | 0.0654 | 0.3836 | 0.8218 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0081 | 0.0003 | 0.0365 | 0.0110 | 0.0711 | 0.0286 | 0.0684 | 0.0204 | 0.0949 | 0.0311 | 0.7198 | 0.9085 | 0.0050 | 0.0092 | 0.0093 | 0.0297 | 0.0328 | 0.0343 | 0.0734 | 0.0847 | 0.1290 | 0.1533 | 0.1917 | 0.2197 | 0.1226 | 0.1327 | 0.1347 | 0.1373 | 0.3015 | 0.1991 | 0.0006 | 0.0026 | 0.0110 | 0.0266 | 0.0747 | 0.1389 | 0.1155 | 0.1259 | 0.5043 | 7 | 9 | 11 | 13 | 20 | 43 | 110 | 258 | 517 | 0.1512 | 39.36 | 4.482 | 0.5817 | 93855.6 | 84800000 | 94200000000 | 120000000000000 | 0.4152 | 0.1980 | 0.0734 | 0.0021 | 0.2052 | 0.0259 | 0.2539 | 0.1687 | 0.1640 | 0.1542 | 0.1373 | 0.1932 | 0.0879 | 0.1763 | 0.0480 | 0.1107 | 0.0165 | 0.0824 | 0.0137 | 0.0866 | 0.0000 | 0.0002 | 0.0007 | 0.0005 | 0.0021 | 0.0003 | 0.0100 | 0.0059 | 0.0491 | 0.0469 | 0.0856 | 0.0756 | 0.0537 | 0.0477 | 0.0753 | 0.0702 | 0.7236 | 0.7526 | 0.0003 | 0.0001 | 0.0018 | 0.0006 | 0.0017 | 0.0025 | 0.0090 | 0.0096 | 0.0589 | 0.0634 | 0.0991 | 0.1035 | 0.0632 | 0.0706 | 0.0877 | 0.0978 | 0.6783 | 0.6519 | 0.0001 | 0.0011 | 0.0020 | 0.0119 | 0.0542 | 0.0904 | 0.0605 | 0.0819 | 0.6977 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 137 | 324 | 5641 | 20747 | 281.5 | 64.71 | 102.70 | 136.65 | 202 | 225 | 243 | 262 | 277 | 293 | 311 | 335 | 366 | 0.0556 | 1153 | 0.979 | 115.25 | 26.87 | 1 | 0.0456 | 257 | 0.0006 | 71.66 | 7.549 | 0.1440 | 83449.7 | 26000000 | 8510000000 | 2920000000000 | 0.4017 | 0.2486 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0000 | 0.0232 | 0.0027 | 0.0713 | 0.0198 | 0.1447 | 0.0392 | 0.1676 | 0.0472 | 0.1783 | 0.0677 | 0.4103 | 0.8235 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0102 | 0.0011 | 0.0291 | 0.0141 | 0.0555 | 0.0255 | 0.0700 | 0.0224 | 0.0851 | 0.0349 | 0.7483 | 0.9020 | 0.0009 | 0.0074 | 0.0085 | 0.0257 | 0.0180 | 0.0662 | 0.0722 | 0.1029 | 0.1472 | 0.1838 | 0.1918 | 0.1618 | 0.1149 | 0.1360 | 0.1434 | 0.1140 | 0.3029 | 0.2022 | 0.0023 | 0.0015 | 0.0072 | 0.0281 | 0.0795 | 0.1228 | 0.1049 | 0.1327 | 0.5209 | 11 | 14 | 17 | 23 | 35 | 63 | 115 | 185 | 286 | 0.0458 | 14.71 | 4.863 | 0.5260 | 29220.6 | 12900000 | 7580000000 | 5510000000000 | 0.5276 | 0.1342 | 0.0999 | 0.0045 | 0.3282 | 0.0294 | 0.3393 | 0.1714 | 0.1201 | 0.2314 | 0.0597 | 0.2369 | 0.0285 | 0.1756 | 0.0132 | 0.0762 | 0.0090 | 0.0458 | 0.0021 | 0.0287 | 0.0003 | 0.0002 | 0.0004 | 0.0007 | 0.0014 | 0.0014 | 0.0118 | 0.0117 | 0.0724 | 0.0573 | 0.1165 | 0.1003 | 0.0799 | 0.0698 | 0.1094 | 0.0976 | 0.6080 | 0.6610 | 0.0005 | 0.0006 | 0.0012 | 0.0025 | 0.0034 | 0.0047 | 0.0207 | 0.0211 | 0.0878 | 0.0967 | 0.1435 | 0.1663 | 0.0940 | 0.0978 | 0.1317 | 0.1352 | 0.5172 | 0.4752 | 0.0002 | 0.0006 | 0.0024 | 0.0191 | 0.0743 | 0.1338 | 0.0863 | 0.1178 | 0.5656 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 916 | 208 | 6312 | 22401 | 516.6 | 108.92 | 194.68 | 249.60 | 387 | 432 | 460 | 485 | 506 | 529 | 554 | 590 | 659 | 0.0487 | 1092 | 1.116 | 137.30 | 45.69 | 1 | 0.0535 | 338 | 0.0007 | 69.42 | 7.543 | 0.1440 | 278766.0 | 157000000 | 92800000000 | 57400000000000 | 0.4428 | 0.2109 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0104 | 0.0019 | 0.0576 | 0.0179 | 0.1165 | 0.0397 | 0.1247 | 0.0358 | 0.1680 | 0.0608 | 0.5208 | 0.8440 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0008 | 0.0320 | 0.0120 | 0.0592 | 0.0239 | 0.0665 | 0.0194 | 0.0912 | 0.0340 | 0.7446 | 0.9099 | 0.0077 | 0.0096 | 0.0132 | 0.0096 | 0.0252 | 0.0382 | 0.0614 | 0.0669 | 0.1107 | 0.1369 | 0.1590 | 0.2452 | 0.0998 | 0.1051 | 0.1239 | 0.1624 | 0.3991 | 0.2261 | 0.0021 | 0.0045 | 0.0156 | 0.0403 | 0.0904 | 0.1255 | 0.1172 | 0.1321 | 0.4722 | 8 | 11 | 15 | 29 | 79 | 153 | 245 | 373 | 559 | 0.0687 | 42.39 | 5.505 | 0.4513 | 100197.0 | 70500000 | 59900000000 | 58200000000000 | 0.4609 | 0.1681 | 0.0552 | 0.0013 | 0.1678 | 0.0137 | 0.2533 | 0.1058 | 0.1683 | 0.1355 | 0.1438 | 0.1985 | 0.1037 | 0.1961 | 0.0500 | 0.1334 | 0.0302 | 0.1063 | 0.0276 | 0.1095 | 0.0003 | 0.0001 | 0.0002 | 0.0003 | 0.0016 | 0.0011 | 0.0067 | 0.0064 | 0.0528 | 0.0424 | 0.0871 | 0.0742 | 0.0642 | 0.0559 | 0.0943 | 0.0845 | 0.6926 | 0.7352 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0026 | 0.0047 | 0.0182 | 0.0210 | 0.0633 | 0.0712 | 0.1119 | 0.1303 | 0.0840 | 0.0811 | 0.1128 | 0.1143 | 0.6064 | 0.5764 | 0.0003 | 0.0010 | 0.0028 | 0.0120 | 0.0577 | 0.0977 | 0.0730 | 0.1042 | 0.6513 |