High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 271 | 234 | | 4849 | 8509 | 138.5 | 37.61 | 168.08 | 116.27 | 97 | 108 | 116 | 125 | 133 | 143 | 153 | 166 | 185 | 0.0903 | 768 | 0.853 | 97.87 | 27.20 | 1 | 0.0524 | 254 | 0.0019 | 23.69 | 6.561 | 0.2428 | 20609.1 | 3310000 | 576000000 | 109000000000 | 0.4479 | 0.1970 | 0.0011 | 0.0000 | 0.0041 | 0.0000 | 0.0103 | 0.0007 | 0.0347 | 0.0030 | 0.0975 | 0.0240 | 0.1680 | 0.0552 | 0.1473 | 0.0550 | 0.1743 | 0.0965 | 0.3626 | 0.7657 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0030 | 0.0000 | 0.0123 | 0.0013 | 0.0355 | 0.0161 | 0.0695 | 0.0309 | 0.0711 | 0.0237 | 0.0993 | 0.0428 | 0.7066 | 0.8852 | 0.0042 | 0.0206 | 0.0084 | 0.0413 | 0.0190 | 0.0324 | 0.0685 | 0.1150 | 0.1496 | 0.1711 | 0.1707 | 0.1917 | 0.1201 | 0.1003 | 0.1465 | 0.0944 | 0.3130 | 0.2330 | 0.0009 | 0.0047 | 0.0117 | 0.0314 | 0.0835 | 0.1234 | 0.1183 | 0.1427 | 0.4833 | 38 | 66 | 89 | 113 | 143 | 180 | 216 | 263 | 330 | 0.0018 | 46.51 | 6.975 | 0.2588 | 41766.1 | 13000000 | 4740000000 | 1930000000000 | 0.4999 | 0.1620 | 0.0124 | 0.0018 | 0.0599 | 0.0036 | 0.1785 | 0.0173 | 0.2094 | 0.0574 | 0.1872 | 0.1344 | 0.1408 | 0.2044 | 0.0982 | 0.1652 | 0.0624 | 0.1709 | 0.0513 | 0.2450 | 0.0000 | 0.0005 | 0.0009 | 0.0009 | 0.0025 | 0.0038 | 0.0156 | 0.0096 | 0.0467 | 0.0356 | 0.0847 | 0.0597 | 0.0774 | 0.0637 | 0.1241 | 0.0957 | 0.6481 | 0.7305 | 0.0014 | 0.0023 | 0.0028 | 0.0064 | 0.0084 | 0.0138 | 0.0298 | 0.0527 | 0.0922 | 0.1087 | 0.1388 | 0.1577 | 0.1247 | 0.1220 | 0.1496 | 0.1298 | 0.4523 | 0.4067 | 0.0000 | 0.0008 | 0.0024 | 0.0176 | 0.0680 | 0.1114 | 0.0973 | 0.1403 | 0.5622 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1116 | 643 | | 4192 | 3538 | 101.2 | 30.48 | 158.91 | 113.21 | 66 | 76 | 84 | 91 | 97 | 104 | 112 | 125 | 141 | 0.1888 | 668 | 0.252 | 105.39 | 16.55 | 4 | 0.1069 | 448 | 0.0013 | 39.51 | 6.913 | 0.1929 | 11171.4 | 1340000 | 175000000 | 24600000000 | 0.4594 | 0.2026 | 0.0014 | 0.0000 | 0.0041 | 0.0009 | 0.0124 | 0.0023 | 0.0464 | 0.0096 | 0.1319 | 0.0422 | 0.1994 | 0.0776 | 0.1641 | 0.0774 | 0.1567 | 0.1235 | 0.2835 | 0.6665 | 0.0006 | 0.0000 | 0.0010 | 0.0005 | 0.0022 | 0.0010 | 0.0128 | 0.0053 | 0.0491 | 0.0264 | 0.0952 | 0.0467 | 0.0789 | 0.0345 | 0.1084 | 0.0632 | 0.6518 | 0.8224 | 0.0000 | 0.0073 | 0.0032 | 0.0218 | 0.0170 | 0.0291 | 0.0668 | 0.1065 | 0.1188 | 0.1574 | 0.1739 | 0.1695 | 0.1294 | 0.1283 | 0.1379 | 0.1259 | 0.3531 | 0.2542 | 0.0016 | 0.0037 | 0.0132 | 0.0390 | 0.0895 | 0.1311 | 0.1101 | 0.1411 | 0.4708 | 37 | 66 | 88 | 111 | 133 | 160 | 195 | 241 | 311 | 0.0052 | 18.73 | 5.833 | 0.3641 | 38065.2 | 12000000 | 4640000000 | 2080000000000 | 0.5210 | 0.1303 | 0.0169 | 0.0013 | 0.0663 | 0.0074 | 0.1808 | 0.0207 | 0.1873 | 0.0702 | 0.1625 | 0.1318 | 0.1443 | 0.1839 | 0.0845 | 0.1498 | 0.0754 | 0.1639 | 0.0819 | 0.2709 | 0.0000 | 0.0000 | 0.0027 | 0.0009 | 0.0038 | 0.0021 | 0.0279 | 0.0141 | 0.0681 | 0.0513 | 0.1217 | 0.0881 | 0.1045 | 0.0783 | 0.1436 | 0.1245 | 0.5279 | 0.6407 | 0.0009 | 0.0047 | 0.0000 | 0.0107 | 0.0119 | 0.0225 | 0.0574 | 0.0664 | 0.1240 | 0.1163 | 0.1559 | 0.1720 | 0.1276 | 0.1139 | 0.1586 | 0.1649 | 0.3637 | 0.3286 | 0.0014 | 0.0028 | 0.0104 | 0.0369 | 0.0828 | 0.1711 | 0.1113 | 0.1474 | 0.4360 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 309 | 735 | | 1819 | 14901 | 73.2 | 15.19 | 136.21 | 157.45 | 56 | 62 | 65 | 67 | 70 | 74 | 79 | 85 | 94 | 0.0571 | 851 | 0.961 | 66.85 | 20.22 | 3 | 0.0995 | 181 | 0.0042 | 13.83 | 5.799 | 0.2858 | 5584.7 | 444991 | 37000000 | 3220000000 | 0.5015 | 0.1554 | 0.0008 | 0.0000 | 0.0047 | 0.0006 | 0.0228 | 0.0012 | 0.0417 | 0.0140 | 0.1133 | 0.0450 | 0.1707 | 0.1040 | 0.1526 | 0.0900 | 0.1794 | 0.1244 | 0.3139 | 0.6209 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0069 | 0.0011 | 0.0202 | 0.0117 | 0.0656 | 0.0362 | 0.1040 | 0.0841 | 0.0807 | 0.0523 | 0.1230 | 0.0885 | 0.5984 | 0.7255 | 0.0095 | 0.0238 | 0.0063 | 0.0357 | 0.0381 | 0.1190 | 0.1175 | 0.2381 | 0.1460 | 0.1905 | 0.2190 | 0.1429 | 0.1238 | 0.0833 | 0.1143 | 0.0833 | 0.2254 | 0.0833 | 0.0025 | 0.0135 | 0.0197 | 0.0492 | 0.1095 | 0.1365 | 0.1267 | 0.1501 | 0.3924 | 14 | 17 | 23 | 40 | 73 | 110 | 160 | 243 | 367 | 0.0319 | 18.03 | 5.311 | 0.4923 | 43340.4 | 19300000 | 10300000000 | 6180000000000 | 0.4512 | 0.1992 | 0.0348 | 0.0006 | 0.1211 | 0.0135 | 0.2124 | 0.0737 | 0.1696 | 0.0995 | 0.1621 | 0.1575 | 0.1286 | 0.1894 | 0.0776 | 0.1317 | 0.0547 | 0.1357 | 0.0391 | 0.1983 | 0.0008 | 0.0000 | 0.0012 | 0.0006 | 0.0050 | 0.0021 | 0.0163 | 0.0107 | 0.0553 | 0.0478 | 0.0947 | 0.0811 | 0.0696 | 0.0552 | 0.0962 | 0.0929 | 0.6610 | 0.7096 | 0.0009 | 0.0008 | 0.0018 | 0.0024 | 0.0075 | 0.0050 | 0.0218 | 0.0214 | 0.0693 | 0.0833 | 0.1160 | 0.1303 | 0.0869 | 0.0844 | 0.1141 | 0.1295 | 0.5816 | 0.5430 | 0.0008 | 0.0010 | 0.0031 | 0.0189 | 0.0617 | 0.1060 | 0.0742 | 0.1094 | 0.6249 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 118 | 70 | | 1754 | 4174 | 82.7 | 19.21 | 183.51 | 192.01 | 60 | 66 | 71 | 76 | 81 | 86 | 92 | 98 | 108 | 0.1445 | 603 | 0.362 | 172.26 | 45.00 | 1 | 0.4025 | 706 | 0.0023 | 27.82 | 6.291 | 0.2092 | 7207.4 | 660678 | 63600000 | 6400000000 | 0.4497 | 0.1988 | 0.0009 | 0.0000 | 0.0066 | 0.0000 | 0.0161 | 0.0031 | 0.0530 | 0.0093 | 0.1258 | 0.0322 | 0.1542 | 0.0811 | 0.1987 | 0.0619 | 0.2271 | 0.1002 | 0.2176 | 0.7123 | 0.0000 | 0.0000 | 0.0036 | 0.0000 | 0.0065 | 0.0017 | 0.0210 | 0.0035 | 0.0564 | 0.0239 | 0.0694 | 0.0554 | 0.0845 | 0.0309 | 0.1185 | 0.0612 | 0.6402 | 0.8233 | 0.0183 | 0.0101 | 0.0367 | 0.0202 | 0.0765 | 0.0808 | 0.1009 | 0.2121 | 0.1407 | 0.2323 | 0.1529 | 0.2222 | 0.1315 | 0.0909 | 0.1070 | 0.0909 | 0.2355 | 0.0404 | 0.0024 | 0.0120 | 0.0240 | 0.0456 | 0.0948 | 0.1116 | 0.1273 | 0.1645 | 0.4178 | 24 | 30 | 42 | 62 | 105 | 161 | 244 | 333 | 444 | 0.0173 | 43.47 | 5.837 | 0.3746 | 70533.6 | 37800000 | 24900000000 | 19100000000000 | 0.4742 | 0.1698 | 0.1259 | 0.0058 | 0.2370 | 0.0559 | 0.2840 | 0.2328 | 0.1457 | 0.1420 | 0.0889 | 0.1700 | 0.0617 | 0.1455 | 0.0420 | 0.0873 | 0.0099 | 0.0733 | 0.0049 | 0.0873 | 0.0011 | 0.0010 | 0.0028 | 0.0020 | 0.0091 | 0.0024 | 0.0300 | 0.0215 | 0.0935 | 0.0842 | 0.1230 | 0.1214 | 0.0941 | 0.0773 | 0.1423 | 0.1214 | 0.5040 | 0.5688 | 0.0007 | 0.0000 | 0.0059 | 0.0051 | 0.0074 | 0.0144 | 0.0368 | 0.0405 | 0.1177 | 0.1267 | 0.1575 | 0.1976 | 0.1302 | 0.1351 | 0.1707 | 0.1520 | 0.3731 | 0.3285 | 0.0013 | 0.0026 | 0.0059 | 0.0300 | 0.1019 | 0.1457 | 0.1130 | 0.1470 | 0.4526 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 470 | 334 | | 17082 | 34713 | 121.5 | 40.86 | 150.26 | 149.90 | 78 | 87 | 96 | 104 | 113 | 124 | 137 | 153 | 176 | 0.0613 | 2127 | 0.917 | 53.45 | 21.26 | 5 | 0.0091 | 155 | 0.0008 | 47.08 | 7.438 | 0.1848 | 16426.1 | 2470000 | 412000000 | 75400000000 | 0.5115 | 0.1584 | 0.0012 | 0.0001 | 0.0040 | 0.0001 | 0.0120 | 0.0016 | 0.0473 | 0.0092 | 0.1219 | 0.0386 | 0.1808 | 0.0802 | 0.1691 | 0.0807 | 0.1727 | 0.1152 | 0.2911 | 0.6742 | 0.0005 | 0.0001 | 0.0019 | 0.0001 | 0.0033 | 0.0009 | 0.0140 | 0.0056 | 0.0416 | 0.0205 | 0.0689 | 0.0420 | 0.0618 | 0.0336 | 0.0900 | 0.0533 | 0.7179 | 0.8439 | 0.0012 | 0.0043 | 0.0043 | 0.0104 | 0.0127 | 0.0293 | 0.0437 | 0.0804 | 0.1009 | 0.1268 | 0.1386 | 0.1608 | 0.1105 | 0.1154 | 0.1410 | 0.1334 | 0.4469 | 0.3392 | 0.0011 | 0.0023 | 0.0098 | 0.0256 | 0.0655 | 0.1021 | 0.0917 | 0.1081 | 0.5939 | 13 | 20 | 40 | 73 | 109 | 146 | 192 | 255 | 354 | 0.0246 | 17.30 | 5.572 | 0.4804 | 45049.4 | 19600000 | 11700000000 | 9560000000000 | 0.5599 | 0.1198 | 0.0163 | 0.0018 | 0.0736 | 0.0061 | 0.1603 | 0.0328 | 0.1540 | 0.0660 | 0.1820 | 0.1370 | 0.1647 | 0.1862 | 0.1066 | 0.1461 | 0.0830 | 0.1520 | 0.0595 | 0.2718 | 0.0002 | 0.0004 | 0.0015 | 0.0006 | 0.0032 | 0.0019 | 0.0118 | 0.0080 | 0.0480 | 0.0350 | 0.0826 | 0.0652 | 0.0678 | 0.0531 | 0.0929 | 0.0754 | 0.6920 | 0.7604 | 0.0006 | 0.0013 | 0.0019 | 0.0026 | 0.0068 | 0.0081 | 0.0218 | 0.0295 | 0.0745 | 0.0894 | 0.1255 | 0.1446 | 0.0963 | 0.1068 | 0.1258 | 0.1351 | 0.5468 | 0.4826 | 0.0005 | 0.0014 | 0.0039 | 0.0169 | 0.0590 | 0.1040 | 0.0801 | 0.1148 | 0.6194 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 688 | 324 | | 13758 | 21485 | 122.6 | 40.36 | 202.58 | 231.30 | 76 | 90 | 98 | 107 | 117 | 128 | 141 | 156 | 178 | 0.0872 | 1874 | 0.692 | 86.83 | 17.09 | 4 | 0.0151 | 208 | 0.0009 | 37.58 | 7.369 | 0.2047 | 16661.6 | 2480000 | 400000000 | 69100000000 | 0.4692 | 0.2051 | 0.0024 | 0.0004 | 0.0062 | 0.0006 | 0.0139 | 0.0027 | 0.0405 | 0.0084 | 0.0991 | 0.0326 | 0.1598 | 0.0715 | 0.1633 | 0.0626 | 0.1771 | 0.0877 | 0.3378 | 0.7336 | 0.0011 | 0.0002 | 0.0029 | 0.0003 | 0.0047 | 0.0010 | 0.0145 | 0.0048 | 0.0370 | 0.0172 | 0.0555 | 0.0390 | 0.0585 | 0.0291 | 0.0729 | 0.0411 | 0.7528 | 0.8673 | 0.0020 | 0.0037 | 0.0072 | 0.0067 | 0.0133 | 0.0209 | 0.0372 | 0.0491 | 0.0847 | 0.1098 | 0.1175 | 0.1589 | 0.0893 | 0.1141 | 0.1233 | 0.1387 | 0.5255 | 0.3982 | 0.0010 | 0.0026 | 0.0073 | 0.0221 | 0.0578 | 0.0893 | 0.0766 | 0.1021 | 0.6413 | 15 | 20 | 31 | 57 | 109 | 182 | 259 | 358 | 545 | 0.0237 | 41.98 | 5.971 | 0.4277 | 94535.6 | 60700000 | 46900000000 | 41300000000000 | 0.5071 | 0.1526 | 0.0324 | 0.0022 | 0.1222 | 0.0156 | 0.1953 | 0.0725 | 0.1804 | 0.1085 | 0.1681 | 0.1619 | 0.1340 | 0.1825 | 0.0858 | 0.1314 | 0.0495 | 0.1367 | 0.0324 | 0.1888 | 0.0001 | 0.0005 | 0.0017 | 0.0015 | 0.0035 | 0.0027 | 0.0122 | 0.0106 | 0.0577 | 0.0494 | 0.0901 | 0.0778 | 0.0671 | 0.0552 | 0.0932 | 0.0791 | 0.6743 | 0.7233 | 0.0003 | 0.0010 | 0.0028 | 0.0034 | 0.0068 | 0.0100 | 0.0237 | 0.0359 | 0.0811 | 0.0934 | 0.1246 | 0.1344 | 0.0910 | 0.0879 | 0.1214 | 0.1091 | 0.5482 | 0.5250 | 0.0005 | 0.0019 | 0.0048 | 0.0175 | 0.0673 | 0.1061 | 0.0788 | 0.1115 | 0.6117 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 274 | 223 | | 6457 | 17021 | 77.3 | 19.26 | 210.94 | 213.95 | 57 | 61 | 66 | 70 | 74 | 78 | 84 | 91 | 103 | 0.0644 | 1096 | 0.843 | 90.43 | 26.17 | 1 | 0.0367 | 237 | 0.0028 | 17.12 | 6.228 | 0.2745 | 6348.3 | 556064 | 52200000 | 5250000000 | 0.4510 | 0.1996 | 0.0010 | 0.0000 | 0.0056 | 0.0003 | 0.0133 | 0.0005 | 0.0380 | 0.0061 | 0.0745 | 0.0225 | 0.1425 | 0.0484 | 0.1711 | 0.0522 | 0.2152 | 0.0849 | 0.3389 | 0.7851 | 0.0004 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0000 | 0.0163 | 0.0020 | 0.0342 | 0.0138 | 0.0671 | 0.0273 | 0.0778 | 0.0218 | 0.1102 | 0.0414 | 0.6848 | 0.8935 | 0.0074 | 0.0130 | 0.0197 | 0.0216 | 0.0303 | 0.0670 | 0.0663 | 0.1058 | 0.1286 | 0.1685 | 0.1335 | 0.1598 | 0.1179 | 0.1102 | 0.1605 | 0.1102 | 0.3358 | 0.2441 | 0.0024 | 0.0094 | 0.0171 | 0.0447 | 0.0765 | 0.1024 | 0.1080 | 0.1279 | 0.5114 | 18 | 30 | 63 | 104 | 145 | 194 | 257 | 356 | 511 | 0.0108 | 28.47 | 6.188 | 0.3938 | 90266.1 | 55800000 | 45300000000 | 46700000000000 | 0.5019 | 0.1685 | 0.0158 | 0.0008 | 0.0801 | 0.0060 | 0.1780 | 0.0286 | 0.1711 | 0.0730 | 0.1885 | 0.1548 | 0.1561 | 0.2064 | 0.0991 | 0.1523 | 0.0752 | 0.1528 | 0.0360 | 0.2253 | 0.0009 | 0.0001 | 0.0013 | 0.0006 | 0.0042 | 0.0030 | 0.0144 | 0.0093 | 0.0568 | 0.0438 | 0.0954 | 0.0772 | 0.0796 | 0.0684 | 0.1057 | 0.0967 | 0.6416 | 0.7008 | 0.0013 | 0.0018 | 0.0031 | 0.0027 | 0.0098 | 0.0098 | 0.0233 | 0.0219 | 0.0729 | 0.0825 | 0.1141 | 0.1324 | 0.0873 | 0.0882 | 0.1187 | 0.1185 | 0.5694 | 0.5421 | 0.0022 | 0.0021 | 0.0062 | 0.0230 | 0.0643 | 0.1045 | 0.0826 | 0.1072 | 0.6079 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 701 | 856 | | 7996 | 17307 | 193.6 | 58.72 | 164.59 | 174.51 | 125 | 142 | 158 | 171 | 186 | 201 | 219 | 242 | 276 | 0.0699 | 1209 | 0.390 | 189.19 | 52.01 | 6 | 0.0969 | 775 | 0.0004 | 115.49 | 7.998 | 0.1188 | 40941.8 | 9380000 | 2310000000 | 607000000000 | 0.4229 | 0.2241 | 0.0005 | 0.0000 | 0.0018 | 0.0002 | 0.0094 | 0.0009 | 0.0411 | 0.0074 | 0.1168 | 0.0344 | 0.1900 | 0.0791 | 0.1790 | 0.0803 | 0.1954 | 0.1104 | 0.2659 | 0.6873 | 0.0003 | 0.0000 | 0.0010 | 0.0001 | 0.0019 | 0.0003 | 0.0127 | 0.0035 | 0.0368 | 0.0179 | 0.0736 | 0.0397 | 0.0694 | 0.0336 | 0.0989 | 0.0501 | 0.7053 | 0.8549 | 0.0011 | 0.0022 | 0.0058 | 0.0101 | 0.0132 | 0.0348 | 0.0529 | 0.0886 | 0.1242 | 0.1502 | 0.1564 | 0.1973 | 0.1036 | 0.1424 | 0.1416 | 0.1323 | 0.4012 | 0.2422 | 0.0011 | 0.0014 | 0.0067 | 0.0338 | 0.0799 | 0.1053 | 0.1028 | 0.1274 | 0.5416 | 12 | 17 | 27 | 57 | 103 | 156 | 220 | 301 | 416 | 0.0341 | 36.46 | 5.746 | 0.4218 | 57539.3 | 27000000 | 15300000000 | 10100000000000 | 0.6571 | 0.0586 | 0.0542 | 0.0031 | 0.1783 | 0.0167 | 0.2744 | 0.0940 | 0.1826 | 0.1421 | 0.1310 | 0.1851 | 0.0908 | 0.1972 | 0.0521 | 0.1171 | 0.0258 | 0.1158 | 0.0107 | 0.1290 | 0.0001 | 0.0001 | 0.0009 | 0.0003 | 0.0035 | 0.0017 | 0.0141 | 0.0100 | 0.0637 | 0.0508 | 0.1127 | 0.0947 | 0.0879 | 0.0669 | 0.1267 | 0.1070 | 0.5903 | 0.6684 | 0.0002 | 0.0012 | 0.0024 | 0.0030 | 0.0050 | 0.0089 | 0.0260 | 0.0344 | 0.0869 | 0.1000 | 0.1472 | 0.1606 | 0.1046 | 0.1172 | 0.1475 | 0.1538 | 0.4802 | 0.4209 | 0.0006 | 0.0016 | 0.0037 | 0.0192 | 0.0754 | 0.1313 | 0.0961 | 0.1295 | 0.5426 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 875 | 62 | | 1334 | 3820 | 91.9 | 21.30 | 105.54 | 80.69 | 68 | 74 | 80 | 85 | 90 | 95 | 100 | 106 | 117 | 0.1102 | 421 | 0.866 | 95.82 | 24.17 | 1 | 0.1807 | 241 | 0.0026 | 28.10 | 6.166 | 0.2282 | 8892.5 | 911642 | 99600000 | 11700000000 | 0.4476 | 0.2105 | 0.0034 | 0.0000 | 0.0056 | 0.0000 | 0.0213 | 0.0048 | 0.0369 | 0.0081 | 0.0884 | 0.0306 | 0.1432 | 0.0564 | 0.1454 | 0.0596 | 0.1946 | 0.0854 | 0.3613 | 0.7550 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0157 | 0.0023 | 0.0507 | 0.0235 | 0.1005 | 0.0454 | 0.0811 | 0.0310 | 0.1180 | 0.0613 | 0.6267 | 0.8365 | 0.0419 | 0.0125 | 0.0366 | 0.0375 | 0.0628 | 0.1000 | 0.0785 | 0.1000 | 0.1937 | 0.2125 | 0.2042 | 0.1000 | 0.0628 | 0.0750 | 0.0995 | 0.1375 | 0.2199 | 0.2250 | 0.0016 | 0.0128 | 0.0096 | 0.0465 | 0.1348 | 0.1750 | 0.1236 | 0.1637 | 0.3323 | 28 | 40 | 52 | 68 | 85 | 105 | 126 | 153 | 212 | 0.0130 | 7.64 | 5.068 | 0.4624 | 17649.0 | 4150000 | 1240000000 | 442000000000 | 0.4801 | 0.1727 | 0.0158 | 0.0013 | 0.0706 | 0.0076 | 0.1364 | 0.0297 | 0.1583 | 0.0607 | 0.1754 | 0.1208 | 0.1851 | 0.1720 | 0.1218 | 0.1562 | 0.0938 | 0.1720 | 0.0426 | 0.2796 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0067 | 0.0050 | 0.0249 | 0.0184 | 0.0716 | 0.0537 | 0.1095 | 0.0910 | 0.0851 | 0.0746 | 0.1183 | 0.1065 | 0.5817 | 0.6491 | 0.0036 | 0.0062 | 0.0099 | 0.0075 | 0.0172 | 0.0249 | 0.0506 | 0.0634 | 0.1112 | 0.1045 | 0.1546 | 0.1505 | 0.1103 | 0.1256 | 0.1338 | 0.1381 | 0.4087 | 0.3794 | 0.0013 | 0.0072 | 0.0118 | 0.0301 | 0.0740 | 0.1382 | 0.0950 | 0.1434 | 0.4990 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 733 | | 7026 | 3656 | 100.6 | 30.90 | 148.26 | 167.04 | 65 | 73 | 81 | 89 | 97 | 104 | 113 | 123 | 140 | 0.1726 | 631 | 0.377 | 167.26 | 48.09 | 2 | 0.0985 | 692 | 0.0015 | 26.60 | 6.822 | 0.2400 | 11071.8 | 1330000 | 176000000 | 25200000000 | 0.4612 | 0.1922 | 0.0011 | 0.0000 | 0.0014 | 0.0002 | 0.0100 | 0.0020 | 0.0292 | 0.0062 | 0.0812 | 0.0251 | 0.1558 | 0.0583 | 0.1552 | 0.0650 | 0.1918 | 0.0938 | 0.3742 | 0.7495 | 0.0008 | 0.0000 | 0.0002 | 0.0002 | 0.0038 | 0.0018 | 0.0100 | 0.0042 | 0.0318 | 0.0143 | 0.0552 | 0.0292 | 0.0538 | 0.0280 | 0.0766 | 0.0453 | 0.7678 | 0.8770 | 0.0020 | 0.0030 | 0.0087 | 0.0210 | 0.0113 | 0.0299 | 0.0533 | 0.0629 | 0.1119 | 0.1647 | 0.1519 | 0.1467 | 0.1119 | 0.0943 | 0.1446 | 0.1287 | 0.4044 | 0.3488 | 0.0003 | 0.0038 | 0.0060 | 0.0287 | 0.0581 | 0.0975 | 0.0988 | 0.1287 | 0.5781 | 12 | 15 | 21 | 45 | 85 | 132 | 183 | 263 | 396 | 0.0560 | 25.88 | 5.095 | 0.4821 | 49874.3 | 22900000 | 12600000000 | 7790000000000 | 0.5707 | 0.1133 | 0.0493 | 0.0024 | 0.1525 | 0.0214 | 0.1771 | 0.0688 | 0.1435 | 0.1234 | 0.1525 | 0.1637 | 0.1211 | 0.1827 | 0.0785 | 0.1210 | 0.0807 | 0.1257 | 0.0448 | 0.1910 | 0.0006 | 0.0000 | 0.0019 | 0.0028 | 0.0032 | 0.0022 | 0.0158 | 0.0139 | 0.0676 | 0.0565 | 0.1098 | 0.0925 | 0.0909 | 0.0637 | 0.1199 | 0.1163 | 0.5903 | 0.6521 | 0.0026 | 0.0010 | 0.0009 | 0.0073 | 0.0097 | 0.0114 | 0.0325 | 0.0291 | 0.0958 | 0.1112 | 0.1318 | 0.1424 | 0.1019 | 0.1019 | 0.1371 | 0.1486 | 0.4877 | 0.4470 | 0.0000 | 0.0007 | 0.0037 | 0.0214 | 0.0953 | 0.1071 | 0.0960 | 0.1344 | 0.5414 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1109 | 791 | | 9893 | 20116 | 97.3 | 34.99 | 152.25 | 139.00 | 59 | 71 | 78 | 85 | 92 | 100 | 109 | 122 | 142 | 0.0680 | 1367 | 0.691 | 64.66 | 21.00 | 2 | 0.0208 | 206 | 0.0011 | 48.57 | 7.180 | 0.2021 | 10687.4 | 1320000 | 184000000 | 28700000000 | 0.5283 | 0.1408 | 0.0017 | 0.0000 | 0.0030 | 0.0003 | 0.0286 | 0.0013 | 0.0650 | 0.0096 | 0.1374 | 0.0448 | 0.1825 | 0.0976 | 0.1668 | 0.0904 | 0.1696 | 0.1321 | 0.2454 | 0.6238 | 0.0009 | 0.0000 | 0.0010 | 0.0001 | 0.0048 | 0.0001 | 0.0158 | 0.0049 | 0.0504 | 0.0240 | 0.0807 | 0.0492 | 0.0728 | 0.0375 | 0.1094 | 0.0633 | 0.6642 | 0.8209 | 0.0008 | 0.0032 | 0.0055 | 0.0144 | 0.0152 | 0.0335 | 0.0601 | 0.0813 | 0.1261 | 0.1491 | 0.1582 | 0.1914 | 0.1290 | 0.1148 | 0.1472 | 0.1260 | 0.3579 | 0.2863 | 0.0016 | 0.0025 | 0.0094 | 0.0338 | 0.0912 | 0.1218 | 0.1065 | 0.1342 | 0.4990 | 16 | 34 | 57 | 83 | 111 | 147 | 192 | 251 | 344 | 0.0118 | 24.15 | 5.952 | 0.3916 | 42501.1 | 16300000 | 7740000000 | 4260000000000 | 0.4988 | 0.1607 | 0.0275 | 0.0011 | 0.1169 | 0.0097 | 0.2130 | 0.0538 | 0.1636 | 0.0856 | 0.1683 | 0.1643 | 0.1424 | 0.1882 | 0.0820 | 0.1427 | 0.0568 | 0.1438 | 0.0296 | 0.2107 | 0.0004 | 0.0003 | 0.0017 | 0.0007 | 0.0039 | 0.0041 | 0.0160 | 0.0085 | 0.0595 | 0.0462 | 0.1060 | 0.0850 | 0.0867 | 0.0678 | 0.1130 | 0.1003 | 0.6127 | 0.6871 | 0.0008 | 0.0017 | 0.0031 | 0.0057 | 0.0093 | 0.0109 | 0.0287 | 0.0382 | 0.0867 | 0.1002 | 0.1526 | 0.1644 | 0.1028 | 0.1095 | 0.1329 | 0.1367 | 0.4830 | 0.4326 | 0.0001 | 0.0023 | 0.0070 | 0.0206 | 0.0702 | 0.1325 | 0.0932 | 0.1236 | 0.5506 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 619 | 861 | | 3334 | 9894 | 194.2 | 63.45 | 194.29 | 151.46 | 124 | 139 | 154 | 168 | 183 | 201 | 221 | 246 | 280 | 0.0730 | 722 | 0.462 | 118.15 | 25.02 | 1 | 0.1041 | 347 | 0.0006 | 128.05 | 7.588 | 0.1119 | 41739.0 | 9880000 | 2560000000 | 721000000000 | 0.4295 | 0.2204 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0015 | 0.0524 | 0.0063 | 0.1427 | 0.0431 | 0.1999 | 0.0822 | 0.1730 | 0.0778 | 0.1675 | 0.1202 | 0.2426 | 0.6690 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0039 | 0.0000 | 0.0144 | 0.0039 | 0.0471 | 0.0228 | 0.0781 | 0.0449 | 0.0663 | 0.0308 | 0.0938 | 0.0555 | 0.6958 | 0.8421 | 0.0012 | 0.0050 | 0.0024 | 0.0050 | 0.0060 | 0.0298 | 0.0393 | 0.0720 | 0.1262 | 0.1687 | 0.1738 | 0.1687 | 0.0952 | 0.1092 | 0.1333 | 0.1365 | 0.4226 | 0.3052 | 0.0014 | 0.0014 | 0.0082 | 0.0199 | 0.0694 | 0.1223 | 0.0804 | 0.1154 | 0.5817 | 32 | 63 | 95 | 127 | 160 | 199 | 246 | 304 | 396 | 0.0037 | 29.49 | 6.429 | 0.2958 | 60686.3 | 25300000 | 12900000000 | 7630000000000 | 0.5774 | 0.1179 | 0.0296 | 0.0011 | 0.1266 | 0.0053 | 0.2181 | 0.0429 | 0.1967 | 0.0911 | 0.1622 | 0.1735 | 0.1184 | 0.2026 | 0.0789 | 0.1626 | 0.0488 | 0.1505 | 0.0208 | 0.1703 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0034 | 0.0016 | 0.0232 | 0.0134 | 0.0774 | 0.0517 | 0.1295 | 0.0963 | 0.1053 | 0.0884 | 0.1348 | 0.1199 | 0.5252 | 0.6283 | 0.0006 | 0.0032 | 0.0043 | 0.0073 | 0.0115 | 0.0218 | 0.0449 | 0.0638 | 0.1172 | 0.1344 | 0.1596 | 0.1707 | 0.1206 | 0.1287 | 0.1522 | 0.1493 | 0.3890 | 0.3208 | 0.0015 | 0.0027 | 0.0089 | 0.0332 | 0.0904 | 0.1524 | 0.1096 | 0.1362 | 0.4652 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 878 | 807 | | 10754 | 19812 | 116.0 | 43.13 | 194.64 | 157.60 | 65 | 82 | 93 | 102 | 112 | 123 | 135 | 149 | 172 | 0.0642 | 1271 | 0.701 | 121.38 | 37.80 | 4 | 0.0306 | 329 | 0.0008 | 52.90 | 7.469 | 0.1941 | 15319.9 | 2250000 | 364000000 | 64300000000 | 0.4765 | 0.1880 | 0.0006 | 0.0001 | 0.0032 | 0.0001 | 0.0194 | 0.0024 | 0.0533 | 0.0076 | 0.1280 | 0.0387 | 0.1883 | 0.0918 | 0.1576 | 0.0840 | 0.1783 | 0.1211 | 0.2713 | 0.6543 | 0.0003 | 0.0001 | 0.0008 | 0.0001 | 0.0029 | 0.0005 | 0.0110 | 0.0026 | 0.0381 | 0.0187 | 0.0691 | 0.0430 | 0.0531 | 0.0292 | 0.0794 | 0.0457 | 0.7453 | 0.8599 | 0.0010 | 0.0048 | 0.0042 | 0.0090 | 0.0143 | 0.0173 | 0.0422 | 0.0932 | 0.1110 | 0.1422 | 0.1679 | 0.1843 | 0.1051 | 0.1208 | 0.1383 | 0.1291 | 0.4159 | 0.2995 | 0.0004 | 0.0024 | 0.0040 | 0.0240 | 0.0640 | 0.1127 | 0.0981 | 0.1189 | 0.5757 | 24 | 54 | 87 | 120 | 156 | 197 | 250 | 321 | 421 | 0.0057 | 23.66 | 6.344 | 0.3471 | 62723.0 | 26200000 | 13000000000 | 7340000000000 | 0.4891 | 0.1628 | 0.0117 | 0.0010 | 0.0772 | 0.0052 | 0.1807 | 0.0303 | 0.1606 | 0.0730 | 0.1758 | 0.1427 | 0.1489 | 0.1946 | 0.1014 | 0.1392 | 0.0787 | 0.1429 | 0.0650 | 0.2710 | 0.0005 | 0.0002 | 0.0014 | 0.0012 | 0.0039 | 0.0026 | 0.0154 | 0.0096 | 0.0533 | 0.0411 | 0.0979 | 0.0799 | 0.0758 | 0.0604 | 0.1021 | 0.0889 | 0.6496 | 0.7162 | 0.0006 | 0.0008 | 0.0023 | 0.0046 | 0.0095 | 0.0083 | 0.0266 | 0.0319 | 0.0762 | 0.0896 | 0.1270 | 0.1474 | 0.0970 | 0.1083 | 0.1330 | 0.1455 | 0.5279 | 0.4636 | 0.0007 | 0.0024 | 0.0055 | 0.0189 | 0.0659 | 0.1138 | 0.0862 | 0.1177 | 0.5890 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1098 | 160 | | 13724 | 21102 | 109.6 | 32.03 | 139.67 | 113.32 | 75 | 84 | 91 | 97 | 104 | 112 | 121 | 133 | 152 | 0.0598 | 1262 | 0.543 | 155.77 | 38.28 | 1 | 0.0358 | 491 | 0.0012 | 36.99 | 7.099 | 0.2067 | 13040.5 | 1690000 | 237000000 | 36400000000 | 0.4757 | 0.1867 | 0.0010 | 0.0001 | 0.0041 | 0.0003 | 0.0130 | 0.0016 | 0.0426 | 0.0043 | 0.0995 | 0.0236 | 0.1665 | 0.0560 | 0.1630 | 0.0574 | 0.1878 | 0.0954 | 0.3226 | 0.7614 | 0.0005 | 0.0001 | 0.0013 | 0.0001 | 0.0034 | 0.0002 | 0.0125 | 0.0008 | 0.0402 | 0.0130 | 0.0734 | 0.0252 | 0.0716 | 0.0218 | 0.1009 | 0.0456 | 0.6963 | 0.8934 | 0.0044 | 0.0054 | 0.0078 | 0.0168 | 0.0271 | 0.0337 | 0.0640 | 0.0804 | 0.1118 | 0.1692 | 0.1406 | 0.1937 | 0.1349 | 0.1026 | 0.1386 | 0.1394 | 0.3707 | 0.2588 | 0.0024 | 0.0058 | 0.0129 | 0.0351 | 0.0814 | 0.1154 | 0.0950 | 0.1140 | 0.5380 | 25 | 40 | 60 | 83 | 110 | 142 | 177 | 222 | 298 | 0.0094 | 10.78 | 5.597 | 0.4544 | 32349.4 | 10000000 | 3730000000 | 1590000000000 | 0.5105 | 0.1695 | 0.0131 | 0.0019 | 0.0728 | 0.0040 | 0.1644 | 0.0224 | 0.1683 | 0.0713 | 0.1736 | 0.1476 | 0.1439 | 0.1890 | 0.1111 | 0.1477 | 0.0831 | 0.1506 | 0.0697 | 0.2653 | 0.0009 | 0.0007 | 0.0013 | 0.0014 | 0.0035 | 0.0034 | 0.0133 | 0.0126 | 0.0502 | 0.0386 | 0.0839 | 0.0657 | 0.0680 | 0.0578 | 0.1044 | 0.0854 | 0.6745 | 0.7344 | 0.0012 | 0.0013 | 0.0045 | 0.0041 | 0.0086 | 0.0141 | 0.0281 | 0.0380 | 0.0821 | 0.1031 | 0.1290 | 0.1509 | 0.1030 | 0.1107 | 0.1319 | 0.1375 | 0.5116 | 0.4403 | 0.0013 | 0.0019 | 0.0052 | 0.0196 | 0.0680 | 0.1022 | 0.0904 | 0.1250 | 0.5864 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 836 | 239 | | 7959 | 17179 | 111.4 | 30.75 | 133.54 | 119.53 | 79 | 87 | 93 | 99 | 105 | 113 | 122 | 134 | 152 | 0.0646 | 1109 | 0.889 | 111.63 | 30.02 | 1 | 0.0362 | 288 | 0.0014 | 37.17 | 6.950 | 0.2080 | 13344.8 | 1730000 | 244000000 | 37300000000 | 0.4636 | 0.2058 | 0.0004 | 0.0000 | 0.0029 | 0.0004 | 0.0141 | 0.0018 | 0.0306 | 0.0034 | 0.0937 | 0.0251 | 0.1737 | 0.0627 | 0.1673 | 0.0617 | 0.1958 | 0.0914 | 0.3214 | 0.7534 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0051 | 0.0005 | 0.0142 | 0.0017 | 0.0425 | 0.0148 | 0.0738 | 0.0327 | 0.0751 | 0.0242 | 0.1032 | 0.0422 | 0.6851 | 0.8836 | 0.0013 | 0.0058 | 0.0106 | 0.0101 | 0.0188 | 0.0361 | 0.0625 | 0.1111 | 0.1370 | 0.1789 | 0.1739 | 0.2136 | 0.1169 | 0.0823 | 0.1382 | 0.1270 | 0.3408 | 0.2352 | 0.0021 | 0.0050 | 0.0085 | 0.0349 | 0.0830 | 0.1306 | 0.1065 | 0.1317 | 0.4977 | 15 | 24 | 44 | 68 | 100 | 138 | 175 | 228 | 307 | 0.0163 | 13.12 | 5.549 | 0.4536 | 32119.0 | 10100000 | 3750000000 | 1560000000000 | 0.4503 | 0.2056 | 0.0225 | 0.0016 | 0.0936 | 0.0063 | 0.1855 | 0.0369 | 0.1578 | 0.0822 | 0.1606 | 0.1574 | 0.1341 | 0.1888 | 0.1020 | 0.1438 | 0.0831 | 0.1533 | 0.0606 | 0.2296 | 0.0006 | 0.0006 | 0.0006 | 0.0006 | 0.0026 | 0.0026 | 0.0117 | 0.0095 | 0.0448 | 0.0361 | 0.0845 | 0.0642 | 0.0655 | 0.0513 | 0.0979 | 0.0846 | 0.6919 | 0.7505 | 0.0012 | 0.0017 | 0.0042 | 0.0036 | 0.0080 | 0.0091 | 0.0245 | 0.0282 | 0.0726 | 0.0896 | 0.1213 | 0.1353 | 0.0980 | 0.1046 | 0.1294 | 0.1292 | 0.5407 | 0.4988 | 0.0004 | 0.0006 | 0.0042 | 0.0167 | 0.0586 | 0.0988 | 0.0853 | 0.1203 | 0.6151 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1021 | 289 | | 15480 | 20962 | 107.9 | 32.54 | 126.87 | 115.24 | 70 | 80 | 88 | 96 | 104 | 112 | 122 | 133 | 151 | 0.0665 | 1394 | 1.246 | 41.87 | 18.36 | 4 | 0.0075 | 116 | 0.0011 | 32.98 | 7.115 | 0.2122 | 12708.7 | 1630000 | 225000000 | 33600000000 | 0.4430 | 0.2071 | 0.0021 | 0.0002 | 0.0042 | 0.0005 | 0.0146 | 0.0012 | 0.0424 | 0.0071 | 0.1092 | 0.0273 | 0.1709 | 0.0639 | 0.1595 | 0.0673 | 0.1788 | 0.1076 | 0.3183 | 0.7248 | 0.0014 | 0.0002 | 0.0020 | 0.0003 | 0.0039 | 0.0009 | 0.0118 | 0.0037 | 0.0393 | 0.0149 | 0.0650 | 0.0333 | 0.0601 | 0.0290 | 0.0876 | 0.0504 | 0.7289 | 0.8672 | 0.0025 | 0.0080 | 0.0037 | 0.0173 | 0.0202 | 0.0306 | 0.0567 | 0.0766 | 0.1110 | 0.1671 | 0.1514 | 0.1598 | 0.1194 | 0.1152 | 0.1455 | 0.1418 | 0.3896 | 0.2836 | 0.0011 | 0.0021 | 0.0090 | 0.0274 | 0.0627 | 0.1065 | 0.0944 | 0.1225 | 0.5742 | 16 | 27 | 45 | 67 | 94 | 124 | 161 | 212 | 289 | 0.0159 | 8.96 | 5.332 | 0.5036 | 29376.6 | 9390000 | 3750000000 | 1790000000000 | 0.4948 | 0.1572 | 0.0112 | 0.0016 | 0.0613 | 0.0068 | 0.1433 | 0.0245 | 0.1682 | 0.0618 | 0.1919 | 0.1370 | 0.1645 | 0.1771 | 0.1051 | 0.1416 | 0.0836 | 0.1568 | 0.0709 | 0.2928 | 0.0008 | 0.0004 | 0.0011 | 0.0016 | 0.0035 | 0.0026 | 0.0133 | 0.0076 | 0.0489 | 0.0371 | 0.0788 | 0.0577 | 0.0640 | 0.0520 | 0.0930 | 0.0767 | 0.6966 | 0.7643 | 0.0006 | 0.0013 | 0.0028 | 0.0020 | 0.0070 | 0.0071 | 0.0249 | 0.0329 | 0.0705 | 0.0821 | 0.1139 | 0.1305 | 0.0891 | 0.1028 | 0.1163 | 0.1349 | 0.5748 | 0.5065 | 0.0001 | 0.0018 | 0.0055 | 0.0186 | 0.0602 | 0.0898 | 0.0819 | 0.1099 | 0.6321 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 834 | 433 | | 10028 | 23515 | 170.4 | 45.07 | 251.81 | 223.41 | 116 | 130 | 142 | 154 | 167 | 180 | 195 | 212 | 231 | 0.0643 | 1511 | 0.433 | 138.81 | 20.40 | 4 | 0.0343 | 344 | 0.0006 | 58.13 | 7.696 | 0.1518 | 31076.2 | 6010000 | 1230000000 | 261000000000 | 0.4626 | 0.2012 | 0.0014 | 0.0001 | 0.0014 | 0.0000 | 0.0051 | 0.0010 | 0.0350 | 0.0070 | 0.1108 | 0.0315 | 0.1699 | 0.0658 | 0.1503 | 0.0658 | 0.1738 | 0.0971 | 0.3522 | 0.7316 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0007 | 0.0127 | 0.0044 | 0.0411 | 0.0206 | 0.0636 | 0.0401 | 0.0541 | 0.0301 | 0.0732 | 0.0469 | 0.7527 | 0.8573 | 0.0016 | 0.0064 | 0.0036 | 0.0242 | 0.0121 | 0.0382 | 0.0395 | 0.1057 | 0.0999 | 0.1643 | 0.1386 | 0.1771 | 0.1185 | 0.1414 | 0.1350 | 0.1210 | 0.4512 | 0.2217 | 0.0013 | 0.0027 | 0.0055 | 0.0224 | 0.0554 | 0.0952 | 0.0829 | 0.1036 | 0.6310 | 27 | 65 | 104 | 142 | 188 | 246 | 318 | 410 | 550 | 0.0043 | 51.61 | 6.756 | 0.3199 | 113315.0 | 70500000 | 54700000000 | 49800000000000 | 0.5106 | 0.1551 | 0.0197 | 0.0009 | 0.0972 | 0.0050 | 0.2185 | 0.0351 | 0.1851 | 0.0833 | 0.1744 | 0.1635 | 0.1413 | 0.2193 | 0.0821 | 0.1599 | 0.0479 | 0.1407 | 0.0337 | 0.1922 | 0.0004 | 0.0003 | 0.0007 | 0.0007 | 0.0030 | 0.0032 | 0.0179 | 0.0117 | 0.0615 | 0.0449 | 0.0961 | 0.0795 | 0.0799 | 0.0637 | 0.0995 | 0.0868 | 0.6409 | 0.7092 | 0.0008 | 0.0013 | 0.0027 | 0.0038 | 0.0078 | 0.0110 | 0.0324 | 0.0428 | 0.0867 | 0.1042 | 0.1373 | 0.1566 | 0.0965 | 0.1074 | 0.1356 | 0.1445 | 0.5003 | 0.4284 | 0.0004 | 0.0017 | 0.0054 | 0.0273 | 0.0740 | 0.1165 | 0.0851 | 0.1169 | 0.5726 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 974 | 491 | | 2075 | 6138 | 79.2 | 16.85 | 226.62 | 224.68 | 59 | 65 | 70 | 74 | 77 | 82 | 86 | 93 | 102 | 0.0632 | 388 | 0.768 | 127.88 | 34.79 | 1 | 0.1566 | 325 | 0.0032 | 15.64 | 6.011 | 0.2726 | 6562.2 | 567309 | 51100000 | 4800000000 | 0.4688 | 0.1916 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0073 | 0.0005 | 0.0278 | 0.0010 | 0.0805 | 0.0234 | 0.1426 | 0.0426 | 0.1500 | 0.0483 | 0.2004 | 0.0701 | 0.3899 | 0.8141 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0063 | 0.0000 | 0.0322 | 0.0138 | 0.0679 | 0.0256 | 0.0621 | 0.0177 | 0.1059 | 0.0290 | 0.7238 | 0.9140 | 0.0081 | 0.0370 | 0.0270 | 0.0278 | 0.0377 | 0.0926 | 0.0916 | 0.0833 | 0.1456 | 0.1759 | 0.1806 | 0.2407 | 0.1294 | 0.1204 | 0.1240 | 0.1852 | 0.2561 | 0.0370 | 0.0030 | 0.0071 | 0.0163 | 0.0346 | 0.0925 | 0.1209 | 0.1189 | 0.1423 | 0.4644 | 24 | 43 | 68 | 98 | 138 | 204 | 294 | 397 | 550 | 0.0072 | 49.76 | 6.356 | 0.3422 | 101826.0 | 62200000 | 45000000000 | 36400000000000 | 0.4500 | 0.1910 | 0.0311 | 0.0000 | 0.1627 | 0.0071 | 0.2825 | 0.0767 | 0.1686 | 0.1526 | 0.1361 | 0.1859 | 0.1124 | 0.2314 | 0.0503 | 0.1313 | 0.0355 | 0.0987 | 0.0207 | 0.1164 | 0.0008 | 0.0000 | 0.0023 | 0.0013 | 0.0011 | 0.0016 | 0.0106 | 0.0107 | 0.0513 | 0.0417 | 0.1124 | 0.1059 | 0.0724 | 0.0672 | 0.1116 | 0.0820 | 0.6376 | 0.6897 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0056 | 0.0077 | 0.0192 | 0.0195 | 0.0709 | 0.0936 | 0.1478 | 0.1647 | 0.1063 | 0.1043 | 0.1184 | 0.1345 | 0.5314 | 0.4716 | 0.0004 | 0.0013 | 0.0053 | 0.0149 | 0.0605 | 0.1329 | 0.0925 | 0.1136 | 0.5785 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 993 | 394 | | 3513 | 2040 | 83.9 | 23.57 | 182.26 | 150.78 | 58 | 64 | 69 | 74 | 80 | 86 | 93 | 102 | 117 | 0.2098 | 428 | 0.610 | 126.40 | 36.89 | 1 | 0.1153 | 405 | 0.0023 | 17.58 | 6.355 | 0.2696 | 7588.6 | 740923 | 77800000 | 8750000000 | 0.4603 | 0.1930 | 0.0011 | 0.0000 | 0.0056 | 0.0007 | 0.0134 | 0.0026 | 0.0431 | 0.0082 | 0.0968 | 0.0264 | 0.1556 | 0.0541 | 0.1617 | 0.0463 | 0.1796 | 0.0825 | 0.3430 | 0.7792 | 0.0008 | 0.0000 | 0.0012 | 0.0003 | 0.0047 | 0.0003 | 0.0176 | 0.0029 | 0.0434 | 0.0159 | 0.0672 | 0.0308 | 0.0649 | 0.0238 | 0.0883 | 0.0443 | 0.7120 | 0.8816 | 0.0000 | 0.0059 | 0.0052 | 0.0059 | 0.0181 | 0.0265 | 0.0557 | 0.0649 | 0.0959 | 0.1150 | 0.1386 | 0.1593 | 0.1010 | 0.1062 | 0.1451 | 0.1386 | 0.4404 | 0.3776 | 0.0000 | 0.0059 | 0.0092 | 0.0301 | 0.0682 | 0.1009 | 0.0904 | 0.1193 | 0.5760 | 38 | 61 | 78 | 94 | 117 | 169 | 238 | 312 | 410 | 0.0064 | 25.03 | 5.822 | 0.3730 | 55941.1 | 22700000 | 10800000000 | 5710000000000 | 0.5146 | 0.1363 | 0.0251 | 0.0117 | 0.1967 | 0.0156 | 0.1799 | 0.0702 | 0.1674 | 0.1384 | 0.1632 | 0.2242 | 0.1297 | 0.1696 | 0.0795 | 0.1345 | 0.0418 | 0.1228 | 0.0167 | 0.1131 | 0.0011 | 0.0037 | 0.0055 | 0.0037 | 0.0033 | 0.0065 | 0.0199 | 0.0140 | 0.0719 | 0.0699 | 0.1062 | 0.0885 | 0.0752 | 0.0690 | 0.1195 | 0.1053 | 0.5973 | 0.6393 | 0.0000 | 0.0000 | 0.0015 | 0.0036 | 0.0075 | 0.0054 | 0.0256 | 0.0536 | 0.0902 | 0.1161 | 0.1504 | 0.1393 | 0.1158 | 0.1339 | 0.1504 | 0.1750 | 0.4586 | 0.3732 | 0.0000 | 0.0013 | 0.0051 | 0.0269 | 0.0654 | 0.1333 | 0.0885 | 0.1321 | 0.5474 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1223 | 452 | | 6155 | 9803 | 128.7 | 28.06 | 148.51 | 137.13 | 95 | 105 | 112 | 119 | 126 | 133 | 141 | 152 | 166 | 0.0870 | 853 | 0.535 | 195.17 | 41.62 | 2 | 0.0980 | 603 | 0.0012 | 37.11 | 6.972 | 0.1989 | 17339.8 | 2450000 | 361000000 | 55800000000 | 0.4378 | 0.2119 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0000 | 0.0219 | 0.0026 | 0.0706 | 0.0184 | 0.1443 | 0.0426 | 0.1512 | 0.0447 | 0.1856 | 0.0693 | 0.4192 | 0.8224 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0022 | 0.0000 | 0.0078 | 0.0007 | 0.0301 | 0.0139 | 0.0603 | 0.0269 | 0.0630 | 0.0203 | 0.0920 | 0.0328 | 0.7436 | 0.9054 | 0.0055 | 0.0231 | 0.0156 | 0.0423 | 0.0294 | 0.1000 | 0.0725 | 0.1577 | 0.1330 | 0.1577 | 0.1982 | 0.1731 | 0.1330 | 0.1269 | 0.1450 | 0.0885 | 0.2679 | 0.1308 | 0.0021 | 0.0067 | 0.0102 | 0.0376 | 0.0709 | 0.1254 | 0.1180 | 0.1394 | 0.4898 | 14 | 24 | 55 | 81 | 109 | 144 | 187 | 247 | 346 | 0.0183 | 16.97 | 5.620 | 0.4458 | 40857.3 | 15200000 | 6830000000 | 3500000000000 | 0.6750 | 0.0565 | 0.0233 | 0.0013 | 0.1047 | 0.0122 | 0.2115 | 0.0411 | 0.1937 | 0.0746 | 0.1814 | 0.1677 | 0.1513 | 0.1982 | 0.0767 | 0.1700 | 0.0431 | 0.1519 | 0.0144 | 0.1831 | 0.0004 | 0.0005 | 0.0002 | 0.0013 | 0.0026 | 0.0023 | 0.0199 | 0.0116 | 0.0656 | 0.0497 | 0.1179 | 0.0886 | 0.0905 | 0.0744 | 0.1297 | 0.1150 | 0.5731 | 0.6565 | 0.0000 | 0.0012 | 0.0016 | 0.0051 | 0.0090 | 0.0086 | 0.0347 | 0.0451 | 0.1006 | 0.1221 | 0.1546 | 0.1495 | 0.1060 | 0.1197 | 0.1375 | 0.1436 | 0.4560 | 0.4050 | 0.0003 | 0.0016 | 0.0047 | 0.0229 | 0.0938 | 0.1286 | 0.0967 | 0.1442 | 0.5071 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1098 | 496 | | 1949 | 1938 | 124.8 | 50.11 | 251.47 | 187.75 | 64 | 82 | 94 | 105 | 119 | 134 | 149 | 168 | 192 | 0.1858 | 360 | 0.821 | 96.77 | 26.42 | 1 | 0.1442 | 281 | 0.0008 | 114.59 | 7.204 | 0.1050 | 18080.3 | 2940000 | 523000000 | 100000000000 | 0.5094 | 0.1519 | 0.0015 | 0.0000 | 0.0073 | 0.0000 | 0.0601 | 0.0008 | 0.1246 | 0.0061 | 0.2463 | 0.0736 | 0.2625 | 0.1753 | 0.1540 | 0.1578 | 0.0748 | 0.1700 | 0.0689 | 0.4165 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0103 | 0.0036 | 0.0745 | 0.0379 | 0.1149 | 0.0752 | 0.0745 | 0.0578 | 0.1117 | 0.0848 | 0.6117 | 0.7407 | 0.0000 | 0.0000 | 0.0052 | 0.0058 | 0.0086 | 0.0116 | 0.0448 | 0.0785 | 0.1345 | 0.2006 | 0.2103 | 0.2209 | 0.0845 | 0.0930 | 0.1379 | 0.1483 | 0.3741 | 0.2413 | 0.0000 | 0.0022 | 0.0078 | 0.0201 | 0.0983 | 0.1497 | 0.0927 | 0.1352 | 0.4939 | 69 | 95 | 125 | 160 | 191 | 236 | 305 | 403 | 529 | 0.0029 | 36.15 | 6.309 | 0.2943 | 98467.7 | 51400000 | 32500000000 | 23600000000000 | 0.4492 | 0.1782 | 0.0235 | 0.0014 | 0.0882 | 0.0096 | 0.2235 | 0.0193 | 0.1559 | 0.0674 | 0.1500 | 0.1747 | 0.1118 | 0.1678 | 0.0941 | 0.1307 | 0.0735 | 0.1321 | 0.0794 | 0.2971 | 0.0022 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0033 | 0.0194 | 0.0124 | 0.0809 | 0.0521 | 0.1143 | 0.0884 | 0.0895 | 0.0711 | 0.1219 | 0.1207 | 0.5674 | 0.6521 | 0.0000 | 0.0000 | 0.0085 | 0.0083 | 0.0085 | 0.0145 | 0.0341 | 0.0311 | 0.0937 | 0.1284 | 0.1312 | 0.1139 | 0.1039 | 0.0911 | 0.1039 | 0.1304 | 0.5162 | 0.4824 | 0.0000 | 0.0027 | 0.0000 | 0.0396 | 0.0723 | 0.1432 | 0.0900 | 0.1050 | 0.5471 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 935 | 650 | | 4467 | 9610 | 94.8 | 24.92 | 207.00 | 159.98 | 69 | 75 | 80 | 84 | 89 | 95 | 102 | 111 | 128 | 0.0728 | 700 | 0.935 | 58.80 | 21.38 | 2 | 0.0374 | 167 | 0.0023 | 22.65 | 6.438 | 0.2515 | 9610.2 | 1050000 | 124000000 | 15700000000 | 0.4444 | 0.2134 | 0.0007 | 0.0000 | 0.0055 | 0.0010 | 0.0092 | 0.0005 | 0.0283 | 0.0039 | 0.0881 | 0.0217 | 0.1418 | 0.0440 | 0.1686 | 0.0426 | 0.1851 | 0.0733 | 0.3728 | 0.8130 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0048 | 0.0000 | 0.0127 | 0.0016 | 0.0469 | 0.0122 | 0.0720 | 0.0228 | 0.0813 | 0.0176 | 0.1042 | 0.0375 | 0.6764 | 0.9083 | 0.0098 | 0.0137 | 0.0147 | 0.0000 | 0.0244 | 0.0192 | 0.0452 | 0.0658 | 0.1345 | 0.1699 | 0.1516 | 0.2000 | 0.1186 | 0.1151 | 0.1528 | 0.1699 | 0.3484 | 0.2466 | 0.0039 | 0.0055 | 0.0171 | 0.0473 | 0.0892 | 0.1244 | 0.1007 | 0.1172 | 0.4948 | 54 | 84 | 111 | 137 | 168 | 203 | 242 | 303 | 400 | 0.0032 | 28.25 | 6.373 | 0.3196 | 68440.7 | 32700000 | 20600000000 | 15800000000000 | 0.5401 | 0.1476 | 0.0155 | 0.0007 | 0.0447 | 0.0007 | 0.1182 | 0.0190 | 0.1771 | 0.0542 | 0.2087 | 0.1259 | 0.1908 | 0.1667 | 0.1258 | 0.1621 | 0.0810 | 0.1828 | 0.0382 | 0.2878 | 0.0008 | 0.0002 | 0.0010 | 0.0003 | 0.0045 | 0.0026 | 0.0207 | 0.0082 | 0.0649 | 0.0465 | 0.1107 | 0.0798 | 0.0944 | 0.0796 | 0.1265 | 0.1118 | 0.5765 | 0.6712 | 0.0018 | 0.0019 | 0.0080 | 0.0062 | 0.0123 | 0.0162 | 0.0355 | 0.0380 | 0.0952 | 0.1102 | 0.1509 | 0.1501 | 0.0955 | 0.1083 | 0.1404 | 0.1406 | 0.4604 | 0.4285 | 0.0005 | 0.0013 | 0.0099 | 0.0259 | 0.0863 | 0.1255 | 0.0978 | 0.1408 | 0.5120 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 750 | 676 | | 11146 | 21855 | 106.6 | 28.30 | 189.51 | 171.91 | 74 | 83 | 90 | 97 | 103 | 110 | 118 | 128 | 143 | 0.0573 | 1252 | 0.886 | 106.10 | 29.53 | 1 | 0.0241 | 269 | 0.0014 | 32.07 | 6.896 | 0.2173 | 12166.0 | 1490000 | 200000000 | 29600000000 | 0.4458 | 0.2114 | 0.0009 | 0.0000 | 0.0026 | 0.0003 | 0.0096 | 0.0013 | 0.0300 | 0.0038 | 0.0861 | 0.0213 | 0.1508 | 0.0508 | 0.1608 | 0.0587 | 0.1819 | 0.0839 | 0.3773 | 0.7799 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0039 | 0.0003 | 0.0101 | 0.0021 | 0.0393 | 0.0133 | 0.0634 | 0.0258 | 0.0685 | 0.0231 | 0.0980 | 0.0366 | 0.7155 | 0.8988 | 0.0018 | 0.0088 | 0.0088 | 0.0164 | 0.0226 | 0.0582 | 0.0647 | 0.1239 | 0.1317 | 0.2010 | 0.1714 | 0.1795 | 0.1183 | 0.1163 | 0.1423 | 0.1277 | 0.3383 | 0.1681 | 0.0014 | 0.0032 | 0.0116 | 0.0332 | 0.0812 | 0.1162 | 0.1018 | 0.1287 | 0.5226 | 16 | 35 | 67 | 103 | 142 | 190 | 249 | 320 | 433 | 0.0120 | 37.39 | 6.296 | 0.3650 | 65463.6 | 30100000 | 16600000000 | 10400000000000 | 0.5497 | 0.1277 | 0.0358 | 0.0017 | 0.1299 | 0.0109 | 0.2197 | 0.0768 | 0.1613 | 0.1097 | 0.1616 | 0.1610 | 0.1328 | 0.1855 | 0.0738 | 0.1385 | 0.0543 | 0.1308 | 0.0308 | 0.1851 | 0.0000 | 0.0000 | 0.0012 | 0.0012 | 0.0025 | 0.0022 | 0.0135 | 0.0090 | 0.0598 | 0.0462 | 0.1069 | 0.0836 | 0.0781 | 0.0656 | 0.1195 | 0.1003 | 0.6185 | 0.6919 | 0.0006 | 0.0002 | 0.0018 | 0.0023 | 0.0045 | 0.0088 | 0.0267 | 0.0326 | 0.0915 | 0.1031 | 0.1477 | 0.1742 | 0.1100 | 0.1208 | 0.1446 | 0.1560 | 0.4726 | 0.4020 | 0.0002 | 0.0008 | 0.0031 | 0.0184 | 0.0746 | 0.1276 | 0.0976 | 0.1359 | 0.5419 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1035 | 628 | | 3458 | 8206 | 93.8 | 23.90 | 164.82 | 119.42 | 66 | 74 | 79 | 85 | 91 | 97 | 104 | 113 | 127 | 0.1078 | 885 | 0.355 | 97.08 | 18.11 | 4 | 0.0992 | 343 | 0.0017 | 31.62 | 6.627 | 0.2197 | 9369.6 | 995442 | 112000000 | 13400000000 | 0.5072 | 0.1581 | 0.0015 | 0.0000 | 0.0041 | 0.0003 | 0.0193 | 0.0026 | 0.0491 | 0.0078 | 0.1120 | 0.0342 | 0.1621 | 0.0785 | 0.1682 | 0.0691 | 0.1778 | 0.1092 | 0.3060 | 0.6983 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0049 | 0.0006 | 0.0154 | 0.0030 | 0.0566 | 0.0245 | 0.0779 | 0.0558 | 0.0738 | 0.0349 | 0.1124 | 0.0626 | 0.6576 | 0.8187 | 0.0000 | 0.0233 | 0.0158 | 0.0117 | 0.0288 | 0.0623 | 0.0806 | 0.1440 | 0.1568 | 0.1673 | 0.1683 | 0.1479 | 0.1094 | 0.1012 | 0.1540 | 0.1206 | 0.2863 | 0.2218 | 0.0013 | 0.0064 | 0.0160 | 0.0415 | 0.0958 | 0.1213 | 0.1232 | 0.1430 | 0.4515 | 25 | 62 | 87 | 112 | 142 | 175 | 210 | 257 | 327 | 0.0060 | 20.13 | 5.985 | 0.3796 | 41426.6 | 13400000 | 5300000000 | 2470000000000 | 0.5023 | 0.1523 | 0.0128 | 0.0015 | 0.0745 | 0.0055 | 0.1680 | 0.0312 | 0.1607 | 0.0802 | 0.1796 | 0.1311 | 0.1362 | 0.1697 | 0.1057 | 0.1489 | 0.0910 | 0.1507 | 0.0715 | 0.2812 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0048 | 0.0030 | 0.0166 | 0.0153 | 0.0547 | 0.0413 | 0.1021 | 0.0745 | 0.0780 | 0.0668 | 0.1117 | 0.0947 | 0.6316 | 0.7023 | 0.0011 | 0.0014 | 0.0047 | 0.0048 | 0.0131 | 0.0106 | 0.0367 | 0.0476 | 0.0956 | 0.1264 | 0.1425 | 0.1563 | 0.1142 | 0.1317 | 0.1455 | 0.1582 | 0.4465 | 0.3630 | 0.0000 | 0.0011 | 0.0056 | 0.0240 | 0.0760 | 0.1185 | 0.0978 | 0.1440 | 0.5328 |