High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 919 900 image if available 2948 8244 666.3 129.72 46.17 98.68 485 545 590 628 667 705 744 787 840 0.0761 627 1.113 69.64 24.02 1 0.0580 171 0.0007 51.40 7.349 0.1601 460748.0
329000000
243000000000
184000000000000
0.3935 0.2423 0.0000 0.0000 0.0016 0.0000 0.0016 0.0000 0.0110 0.0014 0.0460 0.0183 0.0826 0.0341 0.0727 0.0251 0.1130 0.0389 0.6715 0.8822 0.0000 0.0000 0.0004 0.0000 0.0000 0.0000 0.0041 0.0007 0.0202 0.0156 0.0326 0.0302 0.0223 0.0156 0.0396 0.0282 0.8808 0.9097 0.0019 0.0000 0.0039 0.0476 0.0273 0.0476 0.0253 0.1905 0.0916 0.2857 0.1443 0.1190 0.1033 0.2381 0.1618 0.0714 0.4405 0.0000 0.0007 0.0007 0.0027 0.0115 0.0392 0.0635 0.0581 0.0878 0.7360 9 11 12 14 16 21 28 43 87 0.1378 4.69 3.060 0.7458 11867.4
6550000
4590000000
3630000000000
0.6519 0.0809 0.0058 0.0114 0.0378 0.0178 0.0683 0.0242 0.1541 0.0604 0.1788 0.0768 0.1788 0.1230 0.1541 0.1393 0.1424 0.1628 0.0799 0.3845 0.0010 0.0064 0.0066 0.0092 0.0082 0.0104 0.0255 0.0249 0.0541 0.0385 0.0745 0.0686 0.0760 0.0735 0.1102 0.0951 0.6439 0.6732 0.0008 0.0018 0.0063 0.0055 0.0181 0.0101 0.0291 0.0194 0.0708 0.0738 0.0904 0.1042 0.0818 0.0821 0.1344 0.1245 0.5684 0.5784 0.0032 0.0051 0.0154 0.0199 0.0656 0.0836 0.0855 0.1215 0.6000
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 340 406 image if available 471 6514 857.4 228.67 9.61 2.99 549 627 690 770 842 920 1002 1103 1189 0.0711 463 1.310 25.32 10.63 1 0.1423 67 0.0025 78.35 6.025 0.1012 787377.0
767000000
784000000000
832000000000000
0.3659 0.2545 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0099 0.0024 0.1034 0.0622 0.2512 0.0909 0.1281 0.0646 0.1823 0.0933 0.3251 0.6866 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0061 0.0022 0.0515 0.0500 0.0879 0.0609 0.0424 0.0391 0.0515 0.0543 0.7606 0.7935 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0079 0.0476 0.0787 0.1667 0.1496 0.1667 0.0315 0.0952 0.1260 0.1667 0.6063 0.3571 0.0000 0.0000 0.0000 0.0089 0.0536 0.1161 0.0402 0.0714 0.7098 6 7 8 9 9 10 11 12 13 0.0120 10.83 4.800 0.3191 101.2
1165.12
14657.4
201923
0.4760 0.1625 0.0062 0.0009 0.0309 0.0025 0.0752 0.0063 0.1498 0.0201 0.2096 0.0366 0.2372 0.0807 0.1938 0.1532 0.0783 0.3133 0.0190 0.3862 0.0016 0.0000 0.0096 0.0007 0.0200 0.0031 0.0446 0.0111 0.0824 0.0214 0.1177 0.0415 0.1815 0.0663 0.2235 0.1853 0.3192 0.6707 0.1143 0.2295 0.1414 0.1525 0.1455 0.1311 0.1299 0.0803 0.1225 0.0738 0.1049 0.0754 0.0683 0.0623 0.0751 0.1049 0.0981 0.0902 0.0313 0.0568 0.1064 0.1471 0.1279 0.1328 0.1432 0.1233 0.1312
MCF 10A A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 1039 381 image if available 3800 9893 128.9 35.24 177.58 105.97 91 99 107 113 121 131 142 156 177 0.0668 661 1.078 92.18 30.89 1 0.0611 232 0.0025 19.96 6.337 0.2693 17862.2
2670000
431000000
74800000000
0.4064 0.2310 0.0020 0.0000 0.0049 0.0000 0.0133 0.0003 0.0405 0.0023 0.0968 0.0290 0.1532 0.0582 0.1502 0.0603 0.1789 0.0892 0.3602 0.7607 0.0007 0.0000 0.0028 0.0000 0.0032 0.0000 0.0142 0.0011 0.0383 0.0165 0.0663 0.0315 0.0670 0.0221 0.1018 0.0464 0.7057 0.8824 0.0013 0.0000 0.0025 0.0150 0.0226 0.0240 0.0477 0.1201 0.1206 0.1592 0.1520 0.1742 0.1244 0.1171 0.1595 0.1411 0.3693 0.2492 0.0019 0.0038 0.0107 0.0239 0.0704 0.1157 0.0855 0.1157 0.5723 56 84 110 137 161 189 217 254 321 0.0018 32.40 6.743 0.2735 42762.9
12800000
4530000000
1830000000000
0.5224 0.1428 0.0069 0.0004 0.0360 0.0032 0.1033 0.0123 0.1645 0.0379 0.1920 0.0917 0.1882 0.1453 0.1446 0.1523 0.1037 0.1707 0.0608 0.3863 0.0007 0.0000 0.0011 0.0007 0.0051 0.0014 0.0161 0.0074 0.0562 0.0314 0.0904 0.0636 0.0907 0.0624 0.1212 0.0865 0.6186 0.7466 0.0019 0.0053 0.0061 0.0144 0.0200 0.0202 0.0517 0.0554 0.0950 0.1391 0.1363 0.1464 0.1266 0.1165 0.1315 0.1310 0.4309 0.3717 0.0011 0.0046 0.0090 0.0264 0.0790 0.1152 0.1061 0.1299 0.5287
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 472 429 image if available 2702 12483 298.7 39.90 33.75 65.19 243 264 280 292 303 312 321 330 347 0.0569 710 0.587 156.06 44.65 2 0.1991 538 0.0038 12.01 5.909 0.3178 90794.9
28100000
8800000000
2800000000000
0.4181 0.2189 0.0000 0.0000 0.0000 0.0000 0.0004 0.0000 0.0082 0.0004 0.0381 0.0222 0.0559 0.0359 0.0563 0.0200 0.0858 0.0333 0.7552 0.8882 0.0000 0.0000 0.0000 0.0000 0.0004 0.0000 0.0045 0.0004 0.0288 0.0222 0.0365 0.0359 0.0337 0.0200 0.0483 0.0333 0.8479 0.8882 0.0064 0.0000 0.0446 0.0000 0.0318 0.0000 0.1019 0.0000 0.1338 0.0000 0.1656 0.0000 0.1529 0.0000 0.1338 0.0000 0.2293 0.0000 0.0000 0.0014 0.0095 0.0210 0.0535 0.0947 0.0947 0.1238 0.6015 7 9 10 11 13 16 21 29 72 0.2585 2.84 2.563 0.8124 5388.1
1890000
937000000
558000000000
0.6147 0.0974 0.0312 0.0161 0.0775 0.0194 0.0763 0.0317 0.1329 0.0506 0.1699 0.1013 0.1642 0.1079 0.1780 0.1240 0.1202 0.1614 0.0497 0.3876 0.0063 0.0091 0.0118 0.0101 0.0074 0.0133 0.0221 0.0195 0.0505 0.0405 0.0660 0.0549 0.0705 0.0613 0.0989 0.0965 0.6665 0.6947 0.0038 0.0000 0.0065 0.0043 0.0076 0.0049 0.0244 0.0232 0.0455 0.0452 0.0764 0.0757 0.0585 0.0550 0.0748 0.0794 0.7026 0.7123 0.0014 0.0082 0.0096 0.0227 0.0537 0.0719 0.0637 0.0928 0.6761
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 354 420 image if available 1298 8819 703.5 137.06 40.06 42.60 498 566 622 685 723 762 800 837 868 0.0693 611 0.939 34.21 8.06 4 0.0624 81 0.0013 60.83 6.801 0.1510 513652.0
387000000
299000000000
236000000000000
0.4003 0.2202 0.0000 0.0000 0.0012 0.0000 0.0012 0.0000 0.0085 0.0008 0.0932 0.0281 0.1538 0.0532 0.1356 0.0258 0.1586 0.0446 0.4479 0.8475 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0019 0.0008 0.0458 0.0281 0.0715 0.0532 0.0372 0.0258 0.0696 0.0446 0.7741 0.8475 0.0045 0.0000 0.0135 0.0000 0.0269 0.0000 0.0628 0.0000 0.1704 0.0000 0.1883 0.0000 0.1390 0.0000 0.1749 0.0000 0.2197 0.0000 0.0000 0.0000 0.0014 0.0124 0.0634 0.1007 0.0703 0.1131 0.6386 12 14 16 19 24 30 39 56 96 0.0579 5.04 3.928 0.6486 3419.8
510086
108000000
28300000000
0.4195 0.2154 0.0197 0.0099 0.0599 0.0129 0.1125 0.0254 0.1289 0.0420 0.1724 0.0884 0.1634 0.1256 0.1330 0.1219 0.1371 0.1819 0.0731 0.3921 0.0057 0.0056 0.0106 0.0065 0.0157 0.0127 0.0205 0.0169 0.0410 0.0340 0.0651 0.0498 0.0576 0.0514 0.0923 0.0910 0.6916 0.7322 0.0014 0.0017 0.0062 0.0028 0.0105 0.0062 0.0253 0.0258 0.0581 0.0624 0.0781 0.0983 0.0696 0.0736 0.0948 0.0893 0.6560 0.6399 0.0019 0.0054 0.0101 0.0260 0.0490 0.0707 0.0634 0.1014 0.6720
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 873 826 image if available 3064 6137 665.1 116.47 15.42 8.04 492 567 616 649 680 707 733 763 800 0.0893 548 0.993 122.00 37.22 1 0.0979 300 0.0008 64.26 7.305 0.1764 455869.0
321000000
230000000000
169000000000000
0.4008 0.2360 0.0000 0.0000 0.0004 0.0003 0.0026 0.0000 0.0061 0.0010 0.0299 0.0170 0.0464 0.0304 0.0438 0.0180 0.0520 0.0277 0.8189 0.9056 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0023 0.0010 0.0186 0.0166 0.0266 0.0282 0.0190 0.0159 0.0274 0.0239 0.9060 0.9143 0.0000 0.0000 0.0063 0.0000 0.0031 0.0000 0.0563 0.0000 0.0875 0.0000 0.1125 0.0000 0.0906 0.0000 0.1125 0.0000 0.5313 0.0000 0.0006 0.0053 0.0029 0.0135 0.0224 0.0494 0.0371 0.0530 0.8158 9 10 11 12 13 15 16 19 25 0.3326 0.28 1.109 0.7287 302.3
7707.87
246475
9230000
0.5740 0.1078 0.0370 0.0041 0.0648 0.0041 0.1039 0.0126 0.1337 0.0236 0.1566 0.0577 0.1880 0.1004 0.1606 0.1497 0.1151 0.2427 0.0403 0.4050 0.0184 0.0004 0.0317 0.0011 0.0455 0.0041 0.0608 0.0114 0.0782 0.0408 0.0945 0.0788 0.0862 0.1063 0.1277 0.1658 0.4570 0.5914 0.0395 0.0410 0.0482 0.0420 0.0556 0.0400 0.0649 0.0470 0.0803 0.0561 0.0770 0.0681 0.0663 0.0681 0.1071 0.1692 0.4612 0.4685 0.0423 0.0379 0.0347 0.0520 0.0863 0.1089 0.1044 0.1262 0.4073
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 125 813 image if available 4044 8852 602.6 91.52 41.19 63.75 467 546 581 603 621 637 653 670 697 0.0916 811 0.861 103.18 25.63 4 0.0601 243 0.0019 32.85 6.649 0.2422 371488.0
233000000
149000000000
95900000000000
0.4344 0.2018 0.0000 0.0000 0.0000 0.0000 0.0006 0.0000 0.0029 0.0008 0.0262 0.0168 0.0455 0.0300 0.0385 0.0173 0.0691 0.0297 0.8172 0.9055 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0011 0.0008 0.0201 0.0167 0.0321 0.0289 0.0201 0.0157 0.0338 0.0282 0.8928 0.9097 0.0279 0.0000 0.0391 0.0000 0.0615 0.1429 0.1006 0.2857 0.1006 0.2857 0.1564 0.2857 0.1229 0.0000 0.0950 0.0000 0.2961 0.0000 0.0008 0.0021 0.0062 0.0181 0.0402 0.0743 0.0812 0.0952 0.6820 9 11 14 16 19 24 32 45 88 0.0559 3.74 3.856 0.6364 5760.6
1520000
505000000
191000000000
0.4879 0.1680 0.0222 0.0179 0.0677 0.0335 0.0812 0.0288 0.1141 0.0594 0.1460 0.0957 0.1470 0.0868 0.1692 0.1094 0.1335 0.1627 0.1190 0.4059 0.0058 0.0099 0.0173 0.0192 0.0142 0.0128 0.0242 0.0271 0.0468 0.0434 0.0560 0.0449 0.0629 0.0545 0.0844 0.0813 0.6884 0.7067 0.0032 0.0069 0.0153 0.0122 0.0159 0.0130 0.0312 0.0298 0.0503 0.0519 0.0751 0.0833 0.0649 0.0596 0.0808 0.0795 0.6635 0.6639 0.0049 0.0113 0.0157 0.0300 0.0458 0.0679 0.0684 0.0915 0.6644
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 524 311 image if available 7833 16316 159.4 129.05 84.65 174.06 65 76 86 97 114 131 150 185 382 0.0834 1360 1.188 60.96 23.71 5 0.0200 157 0.0057 7.18 5.903 0.4831 42052.4
16100000
7440000000
3750000000000
0.4134 0.2024 0.0022 0.0044 0.0039 0.0032 0.0061 0.0041 0.0335 0.0116 0.0754 0.0367 0.0972 0.0576 0.0972 0.0547 0.1056 0.0789 0.5788 0.7488 0.0012 0.0031 0.0021 0.0023 0.0027 0.0029 0.0140 0.0079 0.0273 0.0211 0.0334 0.0280 0.0404 0.0320 0.0507 0.0445 0.8282 0.8580 0.0007 0.0000 0.0007 0.0000 0.0033 0.0000 0.0086 0.0022 0.0213 0.0230 0.0452 0.0445 0.0219 0.0208 0.0359 0.0408 0.8625 0.8687 0.0005 0.0039 0.0043 0.0096 0.0294 0.0487 0.0352 0.0545 0.8140 8 10 12 15 18 24 39 87 242 0.1992 8.64 2.988 0.7068 37461.6
26400000
22100000000
20600000000000
0.5330 0.1352 0.0090 0.0029 0.0336 0.0070 0.0493 0.0187 0.1087 0.0531 0.1659 0.0904 0.1839 0.1376 0.1390 0.1405 0.1312 0.1359 0.1794 0.4140 0.0005 0.0009 0.0029 0.0023 0.0029 0.0042 0.0098 0.0168 0.0383 0.0349 0.0554 0.0519 0.0449 0.0496 0.0660 0.0575 0.7794 0.7817 0.0021 0.0004 0.0017 0.0035 0.0045 0.0047 0.0141 0.0116 0.0497 0.0520 0.0783 0.0849 0.0583 0.0621 0.0852 0.0791 0.7060 0.7017 0.0009 0.0033 0.0045 0.0117 0.0415 0.0667 0.0505 0.0739 0.7471
BT-20
0
DRAQ5 1 TMRE 2 2 2 1 866 124 image if available 7868 18298 509.3 103.27 71.24 63.85 380 418 450 475 502 530 561 596 645 0.0624 1141 1.024 98.60 36.00 1 0.0336 264 0.0007 43.87 7.460 0.1703 270039.0
149000000
85000000000
50300000000000
0.4294 0.2140 0.0004 0.0000 0.0011 0.0001 0.0029 0.0005 0.0116 0.0009 0.0506 0.0141 0.0958 0.0303 0.1076 0.0255 0.1326 0.0412 0.5975 0.8874 0.0000 0.0000 0.0005 0.0000 0.0014 0.0001 0.0044 0.0005 0.0218 0.0097 0.0421 0.0212 0.0456 0.0141 0.0611 0.0214 0.8231 0.9329 0.0015 0.0151 0.0115 0.0075 0.0137 0.0491 0.0634 0.0943 0.0977 0.1698 0.1504 0.1698 0.1107 0.1132 0.1427 0.1208 0.4084 0.2604 0.0005 0.0021 0.0061 0.0192 0.0541 0.0908 0.0842 0.1111 0.6320 12 20 32 44 56 67 82 103 155 0.0160 5.43 4.946 0.5259 9151.3
1720000
410000000
113000000000
0.3977 0.2161 0.0063 0.0014 0.0287 0.0034 0.0848 0.0127 0.1175 0.0402 0.1734 0.0962 0.1759 0.1181 0.1582 0.1348 0.1455 0.1664 0.1097 0.4269 0.0011 0.0006 0.0036 0.0013 0.0059 0.0046 0.0190 0.0127 0.0462 0.0332 0.0641 0.0471 0.0697 0.0516 0.0984 0.0760 0.6920 0.7730 0.0018 0.0028 0.0049 0.0062 0.0101 0.0130 0.0352 0.0370 0.0677 0.0795 0.0948 0.0956 0.0883 0.0857 0.1176 0.1134 0.5795 0.5667 0.0029 0.0063 0.0092 0.0245 0.0550 0.0789 0.0782 0.1114 0.6337
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 886 459 image if available 3618 10342 579.4 120.00 16.41 14.61 402 502 541 570 596 621 644 667 707 0.0617 638 0.872 72.47 21.02 4 0.0506 183 0.0010 57.19 7.152 0.1994 350122.0
218000000
140000000000
91900000000000
0.4429 0.2126 0.0004 0.0000 0.0000 0.0003 0.0008 0.0006 0.0086 0.0012 0.0409 0.0173 0.0601 0.0352 0.0530 0.0212 0.0823 0.0391 0.7539 0.8852 0.0000 0.0000 0.0000 0.0003 0.0000 0.0006 0.0013 0.0009 0.0167 0.0167 0.0279 0.0301 0.0196 0.0140 0.0382 0.0289 0.8963 0.9084 0.0088 0.0000 0.0044 0.0980 0.0199 0.0000 0.0508 0.0980 0.1258 0.1569 0.1523 0.1765 0.1192 0.0588 0.1501 0.1373 0.3687 0.2745 0.0000 0.0005 0.0063 0.0146 0.0466 0.0777 0.0670 0.0869 0.7005 6 8 9 11 13 15 17 20 29 0.2798 0.41 1.932 0.8610 482.7
28156.6
2820000
388000000
0.4309 0.2072 0.0435 0.0205 0.0470 0.0372 0.0509 0.0455 0.0895 0.0516 0.1126 0.0612 0.1545 0.0846 0.2073 0.1008 0.1905 0.1706 0.1043 0.4280 0.0225 0.0151 0.0206 0.0257 0.0213 0.0301 0.0324 0.0319 0.0506 0.0421 0.0689 0.0635 0.0845 0.0648 0.1386 0.1026 0.5606 0.6242 0.0382 0.0267 0.0326 0.0130 0.0336 0.0298 0.0424 0.0360 0.0559 0.0477 0.0634 0.0701 0.0662 0.0775 0.1058 0.0967 0.5620 0.6026 0.0209 0.0300 0.0386 0.0551 0.0695 0.0973 0.0921 0.1086 0.4879
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 273 873 image if available 959 20054 113.6 15.41 28.35 38.32 95 99 103 107 113 117 121 127 135 0.0524 1050 1.034 39.40 13.04 0 0.1064 102 0.0763 0.50 2.832 0.7708 13136.1
1550000
186000000
22800000000
0.4056 0.2400 0.0012 0.0000 0.0036 0.0010 0.0083 0.0031 0.0154 0.0073 0.0473 0.0241 0.0746 0.0640 0.0734 0.0325 0.1006 0.0598 0.6757 0.8080 0.0011 0.0000 0.0032 0.0010 0.0076 0.0031 0.0108 0.0073 0.0314 0.0229 0.0541 0.0615 0.0400 0.0250 0.0639 0.0532 0.7879 0.8259 0.0000 0.0000 0.0127 0.1667 0.0506 0.0000 0.1013 0.5000 0.1266 0.3333 0.1392 0.0000 0.1266 0.0000 0.1266 0.0000 0.3165 0.0000 0.0022 0.0043 0.0152 0.0260 0.0390 0.0758 0.0736 0.1017 0.6623 11 13 15 17 20 22 26 31 40 0.3245 0.91 1.880 0.8551 2272.4
507754
174000000
71000000000
0.5696 0.1296 0.0433 0.0176 0.0600 0.0218 0.0785 0.0264 0.1039 0.0386 0.1265 0.0642 0.1678 0.0809 0.1887 0.1079 0.1421 0.1846 0.0893 0.4581 0.0240 0.0144 0.0282 0.0178 0.0330 0.0204 0.0353 0.0280 0.0502 0.0467 0.0618 0.0603 0.0746 0.0721 0.1061 0.1150 0.5867 0.6253 0.0284 0.0348 0.0315 0.0221 0.0495 0.0172 0.0486 0.0255 0.0769 0.0594 0.0874 0.0790 0.0867 0.0795 0.1126 0.1286 0.4784 0.5540 0.0222 0.0261 0.0286 0.0380 0.0551 0.0752 0.0968 0.1505 0.5076
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 458 196 image if available 2487 4852 502.4 108.13 28.97 67.04 323 396 462 498 525 549 572 595 625 0.1008 489 1.136 122.50 41.00 3 0.1186 295 0.0011 45.67 6.999 0.1815 264107.0
144000000
80400000000
45900000000000
0.4074 0.2236 0.0000 0.0000 0.0007 0.0017 0.0013 0.0017 0.0137 0.0038 0.0586 0.0196 0.1036 0.0325 0.0971 0.0282 0.1153 0.0440 0.6098 0.8684 0.0000 0.0000 0.0000 0.0017 0.0000 0.0017 0.0036 0.0038 0.0214 0.0196 0.0300 0.0311 0.0254 0.0230 0.0376 0.0358 0.8821 0.8834 0.0000 0.0000 0.0093 0.5000 0.0231 0.5000 0.0579 0.0000 0.1435 0.0000 0.2176 0.0000 0.0995 0.0000 0.1435 0.0000 0.3056 0.0000 0.0000 0.0021 0.0027 0.0103 0.0397 0.0637 0.0582 0.0794 0.7440 7 9 10 12 13 16 20 25 39 0.2290 1.64 2.351 0.8187 5332.5
2350000
1240000000
703000000000
0.6224 0.1004 0.0481 0.0325 0.0611 0.0293 0.0722 0.0357 0.0907 0.0325 0.1389 0.0523 0.1889 0.0722 0.1611 0.1094 0.1333 0.1665 0.1056 0.4695 0.0208 0.0226 0.0271 0.0203 0.0253 0.0231 0.0316 0.0220 0.0479 0.0365 0.0949 0.0602 0.0723 0.0747 0.1102 0.1169 0.5700 0.6238 0.0212 0.0086 0.0194 0.0107 0.0212 0.0086 0.0300 0.0193 0.0423 0.0428 0.0758 0.0600 0.0406 0.0450 0.0882 0.0878 0.6614 0.7173 0.0202 0.0265 0.0277 0.0429 0.0542 0.0845 0.0605 0.0782 0.6053
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 365 353 image if available 5969 9686 532.6 131.58 28.76 57.02 329 402 483 536 572 597 619 644 676 0.0840 814 1.039 109.33 39.70 3 0.0476 284 0.0007 61.44 7.562 0.1890 300963.0
177000000
107000000000
65900000000000
0.4153 0.2188 0.0006 0.0000 0.0018 0.0000 0.0036 0.0002 0.0109 0.0011 0.0555 0.0200 0.0772 0.0344 0.0832 0.0215 0.1212 0.0340 0.6460 0.8888 0.0000 0.0000 0.0000 0.0000 0.0002 0.0002 0.0015 0.0011 0.0246 0.0200 0.0316 0.0336 0.0250 0.0204 0.0396 0.0310 0.8774 0.8937 0.0055 0.0000 0.0071 0.0000 0.0188 1.0000 0.0290 0.0000 0.0565 0.0000 0.0863 0.0000 0.0847 0.0000 0.1145 0.0000 0.5976 0.0000 0.0003 0.0000 0.0019 0.0047 0.0314 0.0394 0.0411 0.0607 0.8205 8 10 11 13 16 21 27 36 51 0.1769 0.75 1.769 0.6861 4078.2
2130000
1520000000
1200000000000
0.5279 0.1420 0.0341 0.0214 0.0384 0.0239 0.0803 0.0306 0.0852 0.0415 0.1165 0.0580 0.1541 0.0685 0.1925 0.0928 0.1996 0.1557 0.0994 0.5076 0.0086 0.0112 0.0106 0.0098 0.0185 0.0121 0.0222 0.0179 0.0376 0.0331 0.0539 0.0414 0.0587 0.0485 0.0952 0.0713 0.6946 0.7548 0.0124 0.0117 0.0133 0.0123 0.0143 0.0178 0.0219 0.0270 0.0505 0.0596 0.0657 0.0713 0.0634 0.0774 0.0991 0.1167 0.6594 0.6063 0.0141 0.0137 0.0213 0.0260 0.0416 0.0513 0.0604 0.0853 0.6863
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 797 276 image if available 3081 14857 257.1 73.60 95.99 124.19 175 187 202 218 241 266 296 325 367 0.0703 1045 0.709 60.54 16.03 2 0.0568 175 0.0097 3.01 5.047 0.5308 71538.3
21500000
6880000000
2330000000000
0.3683 0.2682 0.0023 0.0000 0.0053 0.0000 0.0107 0.0015 0.0328 0.0041 0.0710 0.0354 0.1154 0.0479 0.1054 0.0420 0.1398 0.0593 0.5172 0.8099 0.0014 0.0000 0.0019 0.0000 0.0043 0.0007 0.0125 0.0013 0.0288 0.0202 0.0389 0.0276 0.0408 0.0189 0.0504 0.0315 0.8209 0.8998 0.0013 0.0000 0.0000 0.0111 0.0090 0.0028 0.0168 0.0306 0.0530 0.0889 0.0917 0.1306 0.0646 0.1139 0.0904 0.1500 0.6731 0.4722 0.0015 0.0015 0.0052 0.0126 0.0238 0.0535 0.0416 0.0558 0.8045 12 19 29 42 54 70 95 135 230 0.0663 4.54 3.869 0.7237 24635.6
11400000
7270000000
5520000000000
0.4425 0.1810 0.0092 0.0039 0.0252 0.0102 0.0406 0.0158 0.0729 0.0304 0.1237 0.0621 0.1566 0.0900 0.1494 0.0954 0.1869 0.1280 0.2356 0.5641 0.0025 0.0017 0.0033 0.0049 0.0040 0.0052 0.0113 0.0100 0.0302 0.0240 0.0458 0.0344 0.0473 0.0408 0.0691 0.0611 0.7864 0.8179 0.0008 0.0007 0.0034 0.0027 0.0059 0.0050 0.0163 0.0174 0.0487 0.0557 0.0704 0.0795 0.0637 0.0651 0.0789 0.0849 0.7118 0.6890 0.0011 0.0052 0.0059 0.0142 0.0363 0.0542 0.0582 0.0716 0.7533