High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1060 | 312 | | 8531 | 15239 | 406.2 | 51.13 | 226.15 | 245.25 | 342 | 364 | 380 | 392 | 404 | 416 | 431 | 449 | 474 | 0.0668 | 1018 | 0.868 | 57.87 | 17.89 | 1 | 0.0178 | 152 | 0.0013 | 38.37 | 6.954 | 0.1978 | 167626.0 | 70200000 | 29900000000 | 12900000000000 | 0.4561 | 0.1965 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0042 | 0.0000 | 0.0191 | 0.0097 | 0.0469 | 0.0162 | 0.0566 | 0.0088 | 0.0892 | 0.0171 | 0.7825 | 0.9482 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0126 | 0.0097 | 0.0255 | 0.0162 | 0.0268 | 0.0088 | 0.0439 | 0.0152 | 0.8900 | 0.9501 | 0.0146 | 1.0000 | 0.0419 | 0.0000 | 0.0419 | 0.0000 | 0.1129 | 0.0000 | 0.1548 | 0.0000 | 0.1876 | 0.0000 | 0.1220 | 0.0000 | 0.1275 | 0.0000 | 0.1967 | 0.0000 | 0.0026 | 0.0043 | 0.0115 | 0.0412 | 0.0740 | 0.1178 | 0.1135 | 0.1283 | 0.5068 | 15 | 19 | 31 | 68 | 137 | 220 | 311 | 421 | 569 | 0.0214 | 62.72 | 6.209 | 0.3748 | 111286.0 | 74000000 | 60400000000 | 58100000000000 | 0.5099 | 0.1391 | 0.0526 | 0.0022 | 0.1940 | 0.0114 | 0.2544 | 0.1134 | 0.1674 | 0.1438 | 0.1298 | 0.1878 | 0.1032 | 0.1837 | 0.0545 | 0.1188 | 0.0292 | 0.1096 | 0.0149 | 0.1292 | 0.0000 | 0.0001 | 0.0001 | 0.0004 | 0.0007 | 0.0003 | 0.0079 | 0.0047 | 0.0500 | 0.0399 | 0.0844 | 0.0694 | 0.0697 | 0.0522 | 0.1028 | 0.0844 | 0.6841 | 0.7486 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0027 | 0.0049 | 0.0148 | 0.0281 | 0.0769 | 0.0926 | 0.1317 | 0.1530 | 0.1039 | 0.1070 | 0.1377 | 0.1459 | 0.5322 | 0.4672 | 0.0000 | 0.0000 | 0.0020 | 0.0090 | 0.0602 | 0.1073 | 0.0860 | 0.1254 | 0.6102 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 861 | 186 | | 12331 | 15671 | 289.1 | 82.48 | 116.02 | 160.19 | 201 | 225 | 243 | 260 | 276 | 292 | 314 | 345 | 400 | 0.0849 | 1331 | 0.663 | 177.34 | 56.46 | 4 | 0.0431 | 532 | 0.0008 | 58.20 | 7.495 | 0.1717 | 90380.5 | 30600000 | 11200000000 | 4470000000000 | 0.4343 | 0.2144 | 0.0007 | 0.0000 | 0.0013 | 0.0002 | 0.0081 | 0.0007 | 0.0252 | 0.0037 | 0.0800 | 0.0238 | 0.1386 | 0.0531 | 0.1412 | 0.0533 | 0.1670 | 0.0739 | 0.4380 | 0.7912 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0079 | 0.0009 | 0.0344 | 0.0131 | 0.0694 | 0.0240 | 0.0655 | 0.0205 | 0.0934 | 0.0333 | 0.7273 | 0.9081 | 0.0029 | 0.0034 | 0.0074 | 0.0068 | 0.0153 | 0.0316 | 0.0422 | 0.0769 | 0.1071 | 0.1435 | 0.1468 | 0.1973 | 0.1038 | 0.0991 | 0.1443 | 0.1307 | 0.4301 | 0.3108 | 0.0013 | 0.0040 | 0.0106 | 0.0361 | 0.0748 | 0.1272 | 0.0958 | 0.1105 | 0.5396 | 7 | 10 | 13 | 22 | 43 | 73 | 127 | 212 | 335 | 0.0704 | 13.83 | 4.641 | 0.5316 | 39120.6 | 20200000 | 14100000000 | 12400000000000 | 0.5640 | 0.1235 | 0.0406 | 0.0033 | 0.1589 | 0.0200 | 0.2525 | 0.0850 | 0.1954 | 0.1426 | 0.1432 | 0.1904 | 0.1043 | 0.1814 | 0.0579 | 0.1368 | 0.0281 | 0.1111 | 0.0190 | 0.1295 | 0.0000 | 0.0006 | 0.0009 | 0.0012 | 0.0034 | 0.0027 | 0.0101 | 0.0123 | 0.0575 | 0.0454 | 0.0885 | 0.0709 | 0.0600 | 0.0580 | 0.0942 | 0.0801 | 0.6855 | 0.7288 | 0.0002 | 0.0005 | 0.0009 | 0.0015 | 0.0041 | 0.0040 | 0.0175 | 0.0184 | 0.0723 | 0.0875 | 0.1159 | 0.1187 | 0.0771 | 0.0804 | 0.1104 | 0.1200 | 0.6016 | 0.5689 | 0.0000 | 0.0012 | 0.0028 | 0.0153 | 0.0630 | 0.1041 | 0.0675 | 0.1093 | 0.6367 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1132 | 783 | | 5806 | 15602 | 539.4 | 203.19 | 87.63 | 159.39 | 237 | 320 | 418 | 529 | 593 | 630 | 664 | 708 | 771 | 0.0657 | 1025 | 0.615 | 160.90 | 32.02 | 5 | 0.0725 | 421 | 0.0005 | 70.80 | 7.812 | 0.1691 | 332268.0 | 221000000 | 155000000000 | 113000000000000 | 0.4107 | 0.2133 | 0.0000 | 0.0000 | 0.0015 | 0.0005 | 0.0067 | 0.0003 | 0.0370 | 0.0061 | 0.1090 | 0.0389 | 0.1697 | 0.0718 | 0.1398 | 0.0509 | 0.1506 | 0.0799 | 0.3856 | 0.7517 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0013 | 0.0213 | 0.0203 | 0.0424 | 0.0428 | 0.0263 | 0.0197 | 0.0354 | 0.0324 | 0.8711 | 0.8834 | 0.0015 | 0.0000 | 0.0078 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0000 | 0.0553 | 0.0000 | 0.0852 | 0.0000 | 0.0715 | 0.0000 | 0.0832 | 0.0000 | 0.6681 | 1.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0038 | 0.0262 | 0.0487 | 0.0324 | 0.0461 | 0.8422 | 6 | 8 | 9 | 11 | 14 | 23 | 51 | 120 | 297 | 0.1136 | 5.25 | 3.423 | 0.5908 | 33081.1 | 18000000 | 11400000000 | 7790000000000 | 0.5377 | 0.1183 | 0.0619 | 0.0026 | 0.1417 | 0.0166 | 0.2366 | 0.0806 | 0.1761 | 0.1157 | 0.1747 | 0.1905 | 0.0894 | 0.2027 | 0.0688 | 0.1381 | 0.0303 | 0.1234 | 0.0206 | 0.1298 | 0.0010 | 0.0002 | 0.0007 | 0.0002 | 0.0020 | 0.0017 | 0.0110 | 0.0119 | 0.0483 | 0.0430 | 0.0841 | 0.0733 | 0.0507 | 0.0497 | 0.0741 | 0.0696 | 0.7281 | 0.7502 | 0.0003 | 0.0007 | 0.0012 | 0.0036 | 0.0056 | 0.0029 | 0.0148 | 0.0180 | 0.0545 | 0.0546 | 0.0898 | 0.0971 | 0.0634 | 0.0605 | 0.0756 | 0.0840 | 0.6947 | 0.6788 | 0.0003 | 0.0005 | 0.0038 | 0.0110 | 0.0513 | 0.0880 | 0.0548 | 0.0784 | 0.7120 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 693 | | 1758 | 9747 | 194.5 | 65.03 | 7.39 | 2.56 | 126 | 140 | 153 | 164 | 173 | 189 | 216 | 254 | 297 | 0.0806 | 786 | 1.223 | 29.83 | 11.66 | 2 | 0.0438 | 77 | 0.0089 | 2.56 | 5.059 | 0.5219 | 42048.1 | 10100000 | 2640000000 | 742000000000 | 0.3576 | 0.2730 | 0.0013 | 0.0000 | 0.0053 | 0.0007 | 0.0093 | 0.0043 | 0.0200 | 0.0100 | 0.0787 | 0.0400 | 0.1267 | 0.0557 | 0.1067 | 0.0550 | 0.1440 | 0.0764 | 0.5080 | 0.7580 | 0.0008 | 0.0000 | 0.0034 | 0.0006 | 0.0050 | 0.0024 | 0.0101 | 0.0078 | 0.0378 | 0.0269 | 0.0512 | 0.0305 | 0.0419 | 0.0335 | 0.0680 | 0.0449 | 0.7819 | 0.8533 | 0.0023 | 0.0037 | 0.0000 | 0.0037 | 0.0000 | 0.0000 | 0.0090 | 0.0186 | 0.0498 | 0.0520 | 0.0611 | 0.0892 | 0.0452 | 0.0520 | 0.0656 | 0.0743 | 0.7670 | 0.7063 | 0.0000 | 0.0000 | 0.0030 | 0.0076 | 0.0318 | 0.0636 | 0.0394 | 0.0561 | 0.7985 | 4 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0172 | 8.20 | 4.461 | 0.3585 | 61.1 | 562.508 | 5723.84 | 64032.1 | 0.4837 | 0.1687 | 0.0143 | 0.0020 | 0.0491 | 0.0072 | 0.1154 | 0.0186 | 0.1968 | 0.0459 | 0.2244 | 0.0938 | 0.2015 | 0.1724 | 0.1356 | 0.2637 | 0.0542 | 0.2652 | 0.0087 | 0.1312 | 0.0012 | 0.0000 | 0.0093 | 0.0006 | 0.0270 | 0.0038 | 0.0627 | 0.0130 | 0.1007 | 0.0342 | 0.1357 | 0.0750 | 0.1749 | 0.1500 | 0.2022 | 0.2720 | 0.2862 | 0.4515 | 0.1173 | 0.1778 | 0.1454 | 0.1541 | 0.1396 | 0.1171 | 0.1150 | 0.1141 | 0.1015 | 0.0801 | 0.0904 | 0.0898 | 0.0869 | 0.0746 | 0.0800 | 0.0728 | 0.1238 | 0.1195 | 0.0077 | 0.0301 | 0.0649 | 0.1143 | 0.1463 | 0.1559 | 0.1546 | 0.1313 | 0.1950 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 183 | | 11039 | 18903 | 371.9 | 102.23 | 380.94 | 449.84 | 242 | 284 | 315 | 342 | 366 | 390 | 419 | 454 | 501 | 0.0627 | 1185 | 0.969 | 171.70 | 54.42 | 2 | 0.0400 | 442 | 0.0005 | 88.34 | 7.910 | 0.1324 | 148751.0 | 63700000 | 29100000000 | 14200000000000 | 0.4490 | 0.2026 | 0.0005 | 0.0000 | 0.0023 | 0.0001 | 0.0082 | 0.0004 | 0.0272 | 0.0029 | 0.0918 | 0.0254 | 0.1600 | 0.0644 | 0.1476 | 0.0628 | 0.1698 | 0.0955 | 0.3925 | 0.7484 | 0.0000 | 0.0000 | 0.0014 | 0.0001 | 0.0014 | 0.0002 | 0.0061 | 0.0012 | 0.0305 | 0.0163 | 0.0618 | 0.0383 | 0.0559 | 0.0283 | 0.0817 | 0.0492 | 0.7612 | 0.8664 | 0.0017 | 0.0049 | 0.0075 | 0.0233 | 0.0200 | 0.0331 | 0.0553 | 0.1129 | 0.1226 | 0.1755 | 0.1816 | 0.1718 | 0.1131 | 0.1055 | 0.1463 | 0.1313 | 0.3520 | 0.2417 | 0.0010 | 0.0019 | 0.0072 | 0.0234 | 0.0705 | 0.1244 | 0.0974 | 0.1322 | 0.5419 | 14 | 21 | 36 | 86 | 184 | 326 | 510 | 738 | 1059 | 0.0281 | 91.44 | 6.434 | 0.3906 | 347456.0 | 416000000 | 584000000000 | 919000000000000 | 0.5129 | 0.1516 | 0.0334 | 0.0012 | 0.1468 | 0.0085 | 0.2688 | 0.0832 | 0.1754 | 0.1376 | 0.1420 | 0.1939 | 0.1025 | 0.2057 | 0.0710 | 0.1331 | 0.0413 | 0.1056 | 0.0188 | 0.1313 | 0.0004 | 0.0001 | 0.0005 | 0.0002 | 0.0010 | 0.0015 | 0.0098 | 0.0078 | 0.0487 | 0.0404 | 0.0789 | 0.0691 | 0.0535 | 0.0457 | 0.0867 | 0.0737 | 0.7204 | 0.7615 | 0.0003 | 0.0002 | 0.0010 | 0.0016 | 0.0018 | 0.0031 | 0.0173 | 0.0236 | 0.0629 | 0.0721 | 0.1053 | 0.1168 | 0.0686 | 0.0778 | 0.1103 | 0.1157 | 0.6324 | 0.5891 | 0.0001 | 0.0003 | 0.0021 | 0.0129 | 0.0563 | 0.0923 | 0.0627 | 0.0991 | 0.6741 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 900 | 171 | | 3930 | 11298 | 497.7 | 103.96 | 94.40 | 173.19 | 316 | 409 | 476 | 500 | 521 | 540 | 560 | 583 | 613 | 0.0641 | 724 | 0.847 | 112.54 | 33.02 | 4 | 0.0832 | 327 | 0.0011 | 32.58 | 7.096 | 0.2211 | 258499.0 | 139000000 | 76000000000 | 42400000000000 | 0.3874 | 0.2511 | 0.0008 | 0.0003 | 0.0015 | 0.0000 | 0.0057 | 0.0000 | 0.0069 | 0.0008 | 0.0413 | 0.0186 | 0.0462 | 0.0251 | 0.0569 | 0.0178 | 0.0810 | 0.0276 | 0.7597 | 0.9099 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0197 | 0.0186 | 0.0188 | 0.0251 | 0.0172 | 0.0178 | 0.0260 | 0.0276 | 0.9179 | 0.9099 | 0.0052 | 0.0000 | 0.0140 | 0.0000 | 0.0315 | 0.0000 | 0.0542 | 0.0000 | 0.0717 | 0.0000 | 0.0944 | 0.0000 | 0.1119 | 0.0000 | 0.1556 | 0.0000 | 0.4615 | 0.0000 | 0.0012 | 0.0042 | 0.0037 | 0.0108 | 0.0279 | 0.0396 | 0.0500 | 0.0629 | 0.7997 | 6 | 7 | 9 | 10 | 14 | 24 | 52 | 125 | 339 | 0.1266 | 21.37 | 4.235 | 0.6154 | 38902.8 | 22700000 | 15400000000 | 11500000000000 | 0.5106 | 0.1373 | 0.0416 | 0.0018 | 0.1323 | 0.0210 | 0.2420 | 0.0602 | 0.1739 | 0.1267 | 0.1815 | 0.2124 | 0.1361 | 0.2042 | 0.0586 | 0.1258 | 0.0265 | 0.1167 | 0.0076 | 0.1313 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0031 | 0.0015 | 0.0097 | 0.0106 | 0.0497 | 0.0439 | 0.0660 | 0.0569 | 0.0453 | 0.0375 | 0.0729 | 0.0623 | 0.7530 | 0.7860 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0018 | 0.0139 | 0.0172 | 0.0499 | 0.0548 | 0.0820 | 0.0743 | 0.0465 | 0.0535 | 0.0714 | 0.0729 | 0.7342 | 0.7254 | 0.0008 | 0.0000 | 0.0015 | 0.0131 | 0.0528 | 0.0670 | 0.0466 | 0.0751 | 0.7432 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 438 | 881 | | 789 | 8063 | 74.1 | 31.85 | 47.97 | 131.71 | 30 | 40 | 55 | 65 | 73 | 81 | 92 | 101 | 116 | 0.0633 | 510 | 0.386 | 127.58 | 22.47 | 2 | 0.5982 | 472 | 0.0024 | 38.72 | 6.180 | 0.1858 | 6504.0 | 641928 | 68900000 | 7880000000 | 0.3632 | 0.2507 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0538 | 0.0043 | 0.1000 | 0.0172 | 0.2115 | 0.0948 | 0.1808 | 0.1401 | 0.1846 | 0.1185 | 0.1692 | 0.1789 | 0.0962 | 0.4461 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0135 | 0.0049 | 0.0558 | 0.0395 | 0.0673 | 0.0543 | 0.0635 | 0.0329 | 0.0885 | 0.0625 | 0.7115 | 0.8059 | 0.0000 | 0.0000 | 0.0154 | 0.0139 | 0.0077 | 0.0625 | 0.0346 | 0.0694 | 0.0962 | 0.1319 | 0.1269 | 0.1667 | 0.1038 | 0.1528 | 0.1692 | 0.1250 | 0.4462 | 0.2778 | 0.0026 | 0.0000 | 0.0026 | 0.0179 | 0.0742 | 0.0818 | 0.1023 | 0.1560 | 0.5627 | 11 | 13 | 15 | 16 | 18 | 20 | 22 | 26 | 61 | 0.4823 | 4.88 | 1.769 | 0.8585 | 19647.5 | 17700000 | 20000000000 | 25500000000000 | 0.6771 | 0.1020 | 0.0533 | 0.0311 | 0.1557 | 0.0251 | 0.2172 | 0.0621 | 0.2377 | 0.0932 | 0.2008 | 0.1657 | 0.0820 | 0.2027 | 0.0287 | 0.1686 | 0.0164 | 0.1198 | 0.0082 | 0.1317 | 0.0000 | 0.0147 | 0.0009 | 0.0077 | 0.0046 | 0.0105 | 0.0352 | 0.0252 | 0.0897 | 0.0617 | 0.1175 | 0.0870 | 0.1027 | 0.1024 | 0.1036 | 0.1080 | 0.5458 | 0.5827 | 0.0012 | 0.0013 | 0.0036 | 0.0027 | 0.0060 | 0.0080 | 0.0239 | 0.0213 | 0.1004 | 0.1120 | 0.1470 | 0.1600 | 0.1016 | 0.0973 | 0.1147 | 0.1307 | 0.5018 | 0.4667 | 0.0000 | 0.0011 | 0.0074 | 0.0253 | 0.1077 | 0.1267 | 0.0940 | 0.1109 | 0.5269 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1078 | 76 | | 3929 | 6047 | 161.4 | 44.19 | 132.87 | 179.68 | 115 | 126 | 135 | 144 | 153 | 164 | 177 | 192 | 220 | 0.1057 | 639 | 1.011 | 168.43 | 62.07 | 1 | 0.1168 | 459 | 0.0015 | 39.33 | 6.819 | 0.1959 | 28002.9 | 5250000 | 1070000000 | 240000000000 | 0.4412 | 0.2076 | 0.0013 | 0.0000 | 0.0035 | 0.0003 | 0.0083 | 0.0017 | 0.0372 | 0.0034 | 0.0959 | 0.0278 | 0.1713 | 0.0613 | 0.1827 | 0.0573 | 0.1866 | 0.0994 | 0.3132 | 0.7487 | 0.0010 | 0.0000 | 0.0007 | 0.0003 | 0.0023 | 0.0003 | 0.0128 | 0.0000 | 0.0437 | 0.0177 | 0.0801 | 0.0303 | 0.0782 | 0.0230 | 0.1120 | 0.0483 | 0.6693 | 0.8803 | 0.0066 | 0.0058 | 0.0092 | 0.0203 | 0.0328 | 0.0407 | 0.0814 | 0.0872 | 0.1273 | 0.1802 | 0.1654 | 0.2122 | 0.1247 | 0.1105 | 0.1535 | 0.1337 | 0.2992 | 0.2093 | 0.0035 | 0.0035 | 0.0106 | 0.0388 | 0.1052 | 0.1240 | 0.1217 | 0.1499 | 0.4427 | 9 | 12 | 16 | 25 | 49 | 95 | 150 | 233 | 366 | 0.0201 | 68.11 | 5.908 | 0.3842 | 49932.6 | 27200000 | 17800000000 | 13000000000000 | 0.5438 | 0.1149 | 0.0657 | 0.0029 | 0.2044 | 0.0115 | 0.2117 | 0.1319 | 0.1387 | 0.1616 | 0.1515 | 0.2122 | 0.0985 | 0.1539 | 0.0511 | 0.1023 | 0.0547 | 0.0918 | 0.0237 | 0.1319 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0009 | 0.0031 | 0.0234 | 0.0147 | 0.0661 | 0.0570 | 0.0974 | 0.0892 | 0.0793 | 0.0694 | 0.1058 | 0.0927 | 0.6249 | 0.6735 | 0.0017 | 0.0007 | 0.0006 | 0.0000 | 0.0076 | 0.0046 | 0.0285 | 0.0359 | 0.0802 | 0.0894 | 0.1197 | 0.1305 | 0.0953 | 0.0868 | 0.1104 | 0.1194 | 0.5561 | 0.5329 | 0.0010 | 0.0030 | 0.0081 | 0.0186 | 0.0756 | 0.1149 | 0.0832 | 0.1144 | 0.5811 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 394 | 413 | | 10632 | 28722 | 169.7 | 54.58 | 192.66 | 182.13 | 104 | 123 | 136 | 150 | 164 | 180 | 197 | 216 | 243 | 0.0521 | 1497 | 0.576 | 118.81 | 23.02 | 3 | 0.0271 | 288 | 0.0008 | 43.75 | 7.350 | 0.1857 | 31777.4 | 6480000 | 1420000000 | 333000000000 | 0.4827 | 0.1836 | 0.0013 | 0.0000 | 0.0034 | 0.0005 | 0.0185 | 0.0025 | 0.0583 | 0.0094 | 0.1357 | 0.0376 | 0.2026 | 0.0859 | 0.1755 | 0.0911 | 0.1662 | 0.1246 | 0.2386 | 0.6485 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0027 | 0.0009 | 0.0142 | 0.0049 | 0.0416 | 0.0211 | 0.0761 | 0.0422 | 0.0667 | 0.0367 | 0.0911 | 0.0553 | 0.7060 | 0.8389 | 0.0022 | 0.0080 | 0.0032 | 0.0048 | 0.0097 | 0.0177 | 0.0479 | 0.1054 | 0.1186 | 0.1826 | 0.1586 | 0.1955 | 0.1287 | 0.1086 | 0.1536 | 0.1561 | 0.3774 | 0.2212 | 0.0008 | 0.0036 | 0.0069 | 0.0223 | 0.0674 | 0.1032 | 0.0931 | 0.1210 | 0.5817 | 24 | 38 | 60 | 93 | 133 | 183 | 247 | 329 | 451 | 0.0090 | 53.03 | 6.503 | 0.3348 | 70288.5 | 35100000 | 21300000000 | 14900000000000 | 0.4473 | 0.2023 | 0.0513 | 0.0009 | 0.1890 | 0.0115 | 0.2553 | 0.1069 | 0.1609 | 0.1443 | 0.1281 | 0.1866 | 0.0945 | 0.1921 | 0.0604 | 0.1246 | 0.0377 | 0.1011 | 0.0229 | 0.1320 | 0.0004 | 0.0002 | 0.0008 | 0.0006 | 0.0033 | 0.0030 | 0.0171 | 0.0128 | 0.0759 | 0.0579 | 0.1188 | 0.0951 | 0.0890 | 0.0750 | 0.1298 | 0.1102 | 0.5649 | 0.6452 | 0.0008 | 0.0009 | 0.0019 | 0.0028 | 0.0069 | 0.0116 | 0.0329 | 0.0449 | 0.1100 | 0.1226 | 0.1619 | 0.1747 | 0.1106 | 0.1143 | 0.1454 | 0.1490 | 0.4295 | 0.3791 | 0.0003 | 0.0015 | 0.0048 | 0.0246 | 0.0931 | 0.1422 | 0.1029 | 0.1420 | 0.4886 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 617 | 741 | | 9928 | 9082 | 316.0 | 86.06 | 173.78 | 141.29 | 208 | 240 | 266 | 289 | 311 | 334 | 358 | 388 | 431 | 0.1070 | 972 | 1.101 | 126.49 | 42.11 | 1 | 0.0306 | 304 | 0.0003 | 132.65 | 8.162 | 0.1061 | 107236.0 | 38800000 | 14800000000 | 5960000000000 | 0.4826 | 0.1778 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0107 | 0.0001 | 0.0379 | 0.0016 | 0.1130 | 0.0261 | 0.1926 | 0.0663 | 0.1636 | 0.0767 | 0.1676 | 0.1002 | 0.3147 | 0.7290 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0065 | 0.0006 | 0.0383 | 0.0157 | 0.0809 | 0.0357 | 0.0693 | 0.0321 | 0.0909 | 0.0473 | 0.7140 | 0.8686 | 0.0031 | 0.0012 | 0.0040 | 0.0112 | 0.0058 | 0.0423 | 0.0590 | 0.1270 | 0.1709 | 0.2067 | 0.1789 | 0.1806 | 0.1079 | 0.1071 | 0.1514 | 0.1345 | 0.3191 | 0.1893 | 0.0000 | 0.0013 | 0.0023 | 0.0190 | 0.0877 | 0.1367 | 0.1063 | 0.1354 | 0.5113 | 20 | 36 | 65 | 103 | 143 | 189 | 238 | 298 | 377 | 0.0070 | 34.03 | 6.359 | 0.3017 | 50160.7 | 18200000 | 7670000000 | 3630000000000 | 0.5655 | 0.1272 | 0.0383 | 0.0004 | 0.1678 | 0.0090 | 0.2690 | 0.0860 | 0.1670 | 0.1530 | 0.1338 | 0.1699 | 0.1077 | 0.2023 | 0.0600 | 0.1264 | 0.0304 | 0.1210 | 0.0260 | 0.1321 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0032 | 0.0011 | 0.0134 | 0.0098 | 0.0646 | 0.0510 | 0.1245 | 0.0968 | 0.0862 | 0.0748 | 0.1433 | 0.1256 | 0.5643 | 0.6408 | 0.0015 | 0.0008 | 0.0012 | 0.0011 | 0.0071 | 0.0072 | 0.0253 | 0.0459 | 0.1085 | 0.1206 | 0.1520 | 0.1714 | 0.1027 | 0.1251 | 0.1640 | 0.1524 | 0.4377 | 0.3754 | 0.0003 | 0.0003 | 0.0053 | 0.0204 | 0.0876 | 0.1385 | 0.1010 | 0.1491 | 0.4976 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 592 | 447 | | 14268 | 31171 | 276.5 | 63.92 | 156.47 | 200.54 | 198 | 221 | 239 | 256 | 272 | 288 | 306 | 329 | 363 | 0.0479 | 1493 | 1.112 | 122.50 | 42.44 | 2 | 0.0226 | 322 | 0.0005 | 82.25 | 7.811 | 0.1476 | 80557.2 | 24600000 | 7880000000 | 2630000000000 | 0.4955 | 0.1599 | 0.0002 | 0.0001 | 0.0005 | 0.0001 | 0.0060 | 0.0004 | 0.0222 | 0.0013 | 0.0747 | 0.0210 | 0.1425 | 0.0397 | 0.1357 | 0.0415 | 0.1626 | 0.0645 | 0.4556 | 0.8315 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0051 | 0.0007 | 0.0308 | 0.0126 | 0.0628 | 0.0213 | 0.0597 | 0.0187 | 0.0832 | 0.0292 | 0.7574 | 0.9174 | 0.0026 | 0.0113 | 0.0079 | 0.0213 | 0.0229 | 0.0464 | 0.0649 | 0.1004 | 0.1302 | 0.1757 | 0.1868 | 0.2045 | 0.1028 | 0.1142 | 0.1388 | 0.1380 | 0.3432 | 0.1882 | 0.0004 | 0.0016 | 0.0070 | 0.0240 | 0.0851 | 0.1323 | 0.0987 | 0.1321 | 0.5187 | 11 | 14 | 18 | 26 | 57 | 113 | 187 | 292 | 453 | 0.0385 | 36.22 | 5.629 | 0.4704 | 64696.1 | 37000000 | 25200000000 | 19300000000000 | 0.4742 | 0.1836 | 0.0255 | 0.0014 | 0.1594 | 0.0110 | 0.2636 | 0.0618 | 0.1760 | 0.1240 | 0.1590 | 0.2011 | 0.1042 | 0.2139 | 0.0552 | 0.1298 | 0.0320 | 0.1236 | 0.0251 | 0.1333 | 0.0001 | 0.0001 | 0.0011 | 0.0007 | 0.0017 | 0.0016 | 0.0083 | 0.0060 | 0.0509 | 0.0418 | 0.0820 | 0.0672 | 0.0623 | 0.0538 | 0.0920 | 0.0797 | 0.7017 | 0.7491 | 0.0003 | 0.0008 | 0.0022 | 0.0016 | 0.0045 | 0.0054 | 0.0174 | 0.0185 | 0.0624 | 0.0667 | 0.0988 | 0.1125 | 0.0795 | 0.0787 | 0.1028 | 0.1074 | 0.6320 | 0.6083 | 0.0001 | 0.0006 | 0.0031 | 0.0120 | 0.0572 | 0.0936 | 0.0702 | 0.0963 | 0.6669 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 382 | 482 | | 6733 | 6438 | 43.2 | 12.21 | 112.41 | 165.59 | 28 | 32 | 35 | 39 | 42 | 46 | 50 | 54 | 60 | 0.1785 | 1149 | 1.039 | 54.34 | 16.16 | 3 | 0.0192 | 129 | 0.0360 | 0.84 | 3.592 | 0.6983 | 2014.6 | 100311 | 5270000 | 290000000 | 0.3887 | 0.2344 | 0.0060 | 0.0014 | 0.0139 | 0.0039 | 0.0220 | 0.0043 | 0.0460 | 0.0107 | 0.0794 | 0.0318 | 0.1389 | 0.0469 | 0.1480 | 0.0529 | 0.1880 | 0.0959 | 0.3578 | 0.7522 | 0.0027 | 0.0005 | 0.0041 | 0.0010 | 0.0078 | 0.0010 | 0.0188 | 0.0052 | 0.0347 | 0.0229 | 0.0580 | 0.0316 | 0.0586 | 0.0321 | 0.0858 | 0.0495 | 0.7295 | 0.8563 | 0.0070 | 0.0313 | 0.0186 | 0.0224 | 0.0256 | 0.0328 | 0.0413 | 0.0627 | 0.0721 | 0.0687 | 0.0809 | 0.1224 | 0.0878 | 0.1328 | 0.1268 | 0.1597 | 0.5398 | 0.3672 | 0.0033 | 0.0090 | 0.0189 | 0.0269 | 0.0452 | 0.0619 | 0.0736 | 0.0984 | 0.6628 | 7 | 8 | 10 | 12 | 19 | 48 | 124 | 221 | 345 | 0.0718 | 6.66 | 3.779 | 0.5031 | 40050.5 | 19600000 | 11300000000 | 7260000000000 | 0.4549 | 0.1859 | 0.0359 | 0.0046 | 0.1257 | 0.0170 | 0.2036 | 0.0880 | 0.1916 | 0.1173 | 0.1796 | 0.1867 | 0.1168 | 0.1929 | 0.0778 | 0.1312 | 0.0539 | 0.1281 | 0.0150 | 0.1343 | 0.0005 | 0.0008 | 0.0014 | 0.0021 | 0.0023 | 0.0008 | 0.0087 | 0.0068 | 0.0407 | 0.0343 | 0.0535 | 0.0525 | 0.0512 | 0.0423 | 0.0699 | 0.0728 | 0.7719 | 0.7875 | 0.0005 | 0.0000 | 0.0000 | 0.0012 | 0.0022 | 0.0041 | 0.0097 | 0.0146 | 0.0529 | 0.0578 | 0.0707 | 0.0776 | 0.0723 | 0.0712 | 0.0960 | 0.0968 | 0.6958 | 0.6768 | 0.0000 | 0.0010 | 0.0035 | 0.0144 | 0.0416 | 0.0575 | 0.0615 | 0.0878 | 0.7328 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 646 | 621 | | 554 | 3317 | 275.3 | 19.34 | 19.44 | 28.31 | 251 | 261 | 267 | 272 | 276 | 281 | 286 | 292 | 299 | 0.1007 | 334 | 0.832 | 128.55 | 29.97 | 1 | 0.5108 | 283 | 0.0078 | 11.20 | 5.111 | 0.3312 | 76161.1 | 21200000 | 5910000000 | 1660000000000 | 0.3922 | 0.2458 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0453 | 0.0451 | 0.0652 | 0.0650 | 0.0380 | 0.0307 | 0.0580 | 0.0469 | 0.7935 | 0.8123 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0453 | 0.0451 | 0.0652 | 0.0650 | 0.0380 | 0.0307 | 0.0580 | 0.0469 | 0.7935 | 0.8123 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0100 | 0.0300 | 0.0533 | 0.0900 | 0.1667 | 0.1333 | 0.1567 | 0.3533 | 7 | 8 | 9 | 9 | 11 | 12 | 15 | 22 | 33 | 0.0979 | 0.55 | 1.508 | 0.4506 | 1178.9 | 161332 | 29100000 | 5860000000 | 0.5686 | 0.1153 | 0.0480 | 0.0687 | 0.1051 | 0.0634 | 0.1471 | 0.0569 | 0.1952 | 0.0838 | 0.2462 | 0.0967 | 0.1532 | 0.1267 | 0.0811 | 0.1590 | 0.0210 | 0.2105 | 0.0030 | 0.1343 | 0.0121 | 0.0433 | 0.0141 | 0.0377 | 0.0121 | 0.0314 | 0.0313 | 0.0328 | 0.0555 | 0.0370 | 0.0757 | 0.0656 | 0.0858 | 0.0628 | 0.1171 | 0.1172 | 0.5964 | 0.5722 | 0.0091 | 0.0139 | 0.0106 | 0.0239 | 0.0152 | 0.0359 | 0.0410 | 0.0478 | 0.0699 | 0.0896 | 0.1307 | 0.1116 | 0.1185 | 0.1116 | 0.1413 | 0.1434 | 0.4635 | 0.4223 | 0.0059 | 0.0059 | 0.0118 | 0.0403 | 0.0557 | 0.0853 | 0.0936 | 0.1256 | 0.5758 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1038 | 275 | | 2549 | 7083 | 109.6 | 30.68 | 184.05 | 241.54 | 75 | 84 | 91 | 98 | 105 | 112 | 121 | 136 | 154 | 0.0947 | 671 | 1.027 | 25.30 | 7.21 | 3 | 0.0259 | 66 | 0.0014 | 42.86 | 6.822 | 0.1813 | 12951.7 | 1640000 | 223000000 | 32000000000 | 0.4118 | 0.2282 | 0.0015 | 0.0000 | 0.0022 | 0.0005 | 0.0133 | 0.0014 | 0.0517 | 0.0115 | 0.1123 | 0.0460 | 0.1477 | 0.0815 | 0.1388 | 0.0847 | 0.1736 | 0.1119 | 0.3589 | 0.6625 | 0.0010 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0000 | 0.0172 | 0.0078 | 0.0406 | 0.0271 | 0.0630 | 0.0427 | 0.0734 | 0.0447 | 0.0963 | 0.0554 | 0.7033 | 0.8223 | 0.0035 | 0.0038 | 0.0071 | 0.0038 | 0.0088 | 0.0530 | 0.0511 | 0.0758 | 0.0935 | 0.1818 | 0.1587 | 0.2121 | 0.1481 | 0.1326 | 0.1393 | 0.1477 | 0.3898 | 0.1894 | 0.0018 | 0.0083 | 0.0110 | 0.0486 | 0.0734 | 0.1174 | 0.1119 | 0.1321 | 0.4954 | 18 | 22 | 27 | 38 | 68 | 125 | 209 | 326 | 518 | 0.0589 | 18.80 | 4.871 | 0.5443 | 92206.1 | 68200000 | 62400000000 | 65700000000000 | 0.6387 | 0.0776 | 0.0420 | 0.0017 | 0.1714 | 0.0247 | 0.2454 | 0.0945 | 0.1765 | 0.1218 | 0.1513 | 0.1891 | 0.1143 | 0.2121 | 0.0588 | 0.1175 | 0.0303 | 0.1039 | 0.0101 | 0.1346 | 0.0008 | 0.0003 | 0.0004 | 0.0020 | 0.0030 | 0.0020 | 0.0114 | 0.0095 | 0.0568 | 0.0446 | 0.0936 | 0.0936 | 0.0720 | 0.0554 | 0.1258 | 0.1065 | 0.6364 | 0.6860 | 0.0010 | 0.0011 | 0.0020 | 0.0028 | 0.0064 | 0.0073 | 0.0210 | 0.0196 | 0.0787 | 0.0896 | 0.1232 | 0.1328 | 0.0914 | 0.0980 | 0.1355 | 0.1434 | 0.5408 | 0.5053 | 0.0000 | 0.0013 | 0.0022 | 0.0176 | 0.0693 | 0.1015 | 0.0942 | 0.1321 | 0.5818 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1081 | 145 | | 2712 | 9282 | 475.3 | 160.24 | 36.97 | 64.65 | 263 | 299 | 347 | 418 | 487 | 542 | 587 | 633 | 688 | 0.0873 | 810 | 0.985 | 77.18 | 22.00 | 2 | 0.0686 | 186 | 0.0012 | 27.59 | 6.989 | 0.2409 | 251625.0 | 144000000 | 87200000000 | 54900000000000 | 0.3991 | 0.2354 | 0.0000 | 0.0005 | 0.0023 | 0.0016 | 0.0047 | 0.0016 | 0.0280 | 0.0111 | 0.1145 | 0.0379 | 0.1857 | 0.0779 | 0.1449 | 0.0600 | 0.1694 | 0.0937 | 0.3505 | 0.7158 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0013 | 0.0028 | 0.0039 | 0.0289 | 0.0210 | 0.0425 | 0.0394 | 0.0289 | 0.0262 | 0.0408 | 0.0398 | 0.8556 | 0.8675 | 0.0011 | 0.0026 | 0.0000 | 0.0078 | 0.0066 | 0.0129 | 0.0198 | 0.0388 | 0.0484 | 0.0775 | 0.0934 | 0.1318 | 0.0780 | 0.1008 | 0.0868 | 0.1421 | 0.6659 | 0.4858 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0348 | 0.0604 | 0.0434 | 0.0519 | 0.8038 | 5 | 6 | 8 | 10 | 12 | 16 | 25 | 47 | 110 | 0.1009 | 8.52 | 3.705 | 0.6389 | 5545.8 | 1750000 | 914000000 | 650000000000 | 0.5399 | 0.1305 | 0.0775 | 0.0094 | 0.1135 | 0.0353 | 0.1658 | 0.0831 | 0.2036 | 0.1160 | 0.1766 | 0.1599 | 0.1423 | 0.1513 | 0.0811 | 0.1528 | 0.0378 | 0.1567 | 0.0018 | 0.1356 | 0.0032 | 0.0027 | 0.0041 | 0.0056 | 0.0105 | 0.0133 | 0.0215 | 0.0245 | 0.0616 | 0.0553 | 0.0859 | 0.0726 | 0.0656 | 0.0709 | 0.0846 | 0.0968 | 0.6630 | 0.6584 | 0.0016 | 0.0017 | 0.0026 | 0.0029 | 0.0078 | 0.0052 | 0.0246 | 0.0310 | 0.0679 | 0.0700 | 0.0878 | 0.0947 | 0.0669 | 0.0729 | 0.0940 | 0.0884 | 0.6468 | 0.6332 | 0.0023 | 0.0023 | 0.0088 | 0.0236 | 0.0634 | 0.0842 | 0.0648 | 0.0851 | 0.6654 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 477 | 426 | | 5377 | 19317 | 581.1 | 160.29 | 136.17 | 209.41 | 425 | 459 | 484 | 509 | 534 | 566 | 617 | 705 | 822 | 0.0467 | 902 | 1.031 | 97.32 | 27.29 | 2 | 0.0433 | 233 | 0.0008 | 63.73 | 7.412 | 0.1708 | 363397.0 | 246000000 | 181000000000 | 144000000000000 | 0.3855 | 0.2619 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0029 | 0.0002 | 0.0165 | 0.0025 | 0.0836 | 0.0253 | 0.1454 | 0.0498 | 0.1535 | 0.0451 | 0.1707 | 0.0641 | 0.4266 | 0.8129 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0048 | 0.0002 | 0.0452 | 0.0152 | 0.0767 | 0.0238 | 0.0829 | 0.0208 | 0.1093 | 0.0315 | 0.6802 | 0.9084 | 0.0018 | 0.0000 | 0.0018 | 0.0068 | 0.0063 | 0.0068 | 0.0288 | 0.0342 | 0.0728 | 0.1182 | 0.1150 | 0.1541 | 0.0584 | 0.0908 | 0.0988 | 0.1404 | 0.6164 | 0.4486 | 0.0015 | 0.0026 | 0.0128 | 0.0271 | 0.0767 | 0.1048 | 0.0772 | 0.0905 | 0.6069 | 6 | 8 | 9 | 12 | 19 | 59 | 148 | 254 | 436 | 0.1238 | 34.07 | 4.718 | 0.5673 | 62391.7 | 40700000 | 33200000000 | 32300000000000 | 0.4255 | 0.1972 | 0.0345 | 0.0023 | 0.1373 | 0.0110 | 0.2596 | 0.0799 | 0.2092 | 0.1106 | 0.1690 | 0.2037 | 0.1018 | 0.1992 | 0.0495 | 0.1293 | 0.0271 | 0.1275 | 0.0121 | 0.1366 | 0.0003 | 0.0000 | 0.0005 | 0.0001 | 0.0009 | 0.0000 | 0.0059 | 0.0038 | 0.0367 | 0.0320 | 0.0589 | 0.0488 | 0.0443 | 0.0411 | 0.0677 | 0.0553 | 0.7847 | 0.8190 | 0.0002 | 0.0002 | 0.0002 | 0.0014 | 0.0007 | 0.0008 | 0.0100 | 0.0122 | 0.0407 | 0.0531 | 0.0851 | 0.0882 | 0.0557 | 0.0635 | 0.0838 | 0.0904 | 0.7235 | 0.6902 | 0.0000 | 0.0000 | 0.0005 | 0.0065 | 0.0403 | 0.0668 | 0.0522 | 0.0737 | 0.7600 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 305 | | 577 | 1224 | 107.4 | 19.71 | 5.63 | 1.94 | 82 | 89 | 96 | 101 | 108 | 113 | 118 | 125 | 133 | 0.2230 | 273 | 1.197 | 35.36 | 14.21 | 1 | 0.1664 | 96 | 0.0277 | 1.58 | 3.824 | 0.5880 | 11913.2 | 1360000 | 161000000 | 19400000000 | 0.3940 | 0.2372 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0051 | 0.0000 | 0.0304 | 0.0018 | 0.0658 | 0.0406 | 0.1392 | 0.0689 | 0.1342 | 0.0548 | 0.1519 | 0.0707 | 0.4709 | 0.7633 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0000 | 0.0000 | 0.0143 | 0.0017 | 0.0369 | 0.0399 | 0.0656 | 0.0624 | 0.0615 | 0.0295 | 0.0820 | 0.0503 | 0.7377 | 0.8163 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0968 | 0.6364 | 0.1290 | 0.1818 | 0.2796 | 0.0909 | 0.1075 | 0.0909 | 0.1398 | 0.0000 | 0.2473 | 0.0000 | 0.0034 | 0.0068 | 0.0169 | 0.0203 | 0.0811 | 0.0980 | 0.0743 | 0.0845 | 0.6149 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0263 | 7.62 | 3.939 | 0.3680 | 35.5 | 244.168 | 1810.28 | 14316.1 | 0.5714 | 0.1153 | 0.0047 | 0.0000 | 0.0712 | 0.0040 | 0.1377 | 0.0160 | 0.2389 | 0.0419 | 0.2358 | 0.1028 | 0.2294 | 0.1766 | 0.0585 | 0.2535 | 0.0190 | 0.2685 | 0.0047 | 0.1367 | 0.0000 | 0.0000 | 0.0154 | 0.0019 | 0.0475 | 0.0065 | 0.1342 | 0.0260 | 0.1853 | 0.0854 | 0.2601 | 0.1365 | 0.1936 | 0.2201 | 0.1211 | 0.2934 | 0.0428 | 0.2303 | 0.3190 | 0.5467 | 0.3667 | 0.3333 | 0.1571 | 0.1067 | 0.1238 | 0.0133 | 0.0286 | 0.0000 | 0.0048 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0280 | 0.1226 | 0.1559 | 0.1961 | 0.2259 | 0.1471 | 0.0753 | 0.0350 | 0.0140 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 680 | 628 | | 3358 | 11383 | 103.9 | 36.00 | 189.92 | 222.69 | 55 | 73 | 87 | 96 | 104 | 113 | 121 | 132 | 150 | 0.0693 | 789 | 0.744 | 53.00 | 13.15 | 2 | 0.0408 | 137 | 0.0010 | 53.73 | 7.119 | 0.1747 | 12086.9 | 1530000 | 208000000 | 30200000000 | 0.4241 | 0.1918 | 0.0000 | 0.0000 | 0.0045 | 0.0012 | 0.0166 | 0.0028 | 0.0487 | 0.0107 | 0.1236 | 0.0396 | 0.1818 | 0.0832 | 0.1639 | 0.0788 | 0.1748 | 0.1097 | 0.2862 | 0.6739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0065 | 0.0034 | 0.0352 | 0.0250 | 0.0660 | 0.0370 | 0.0567 | 0.0301 | 0.0895 | 0.0510 | 0.7456 | 0.8534 | 0.0011 | 0.0025 | 0.0066 | 0.0127 | 0.0287 | 0.0253 | 0.0562 | 0.0911 | 0.1257 | 0.1671 | 0.1312 | 0.1873 | 0.1125 | 0.1013 | 0.1389 | 0.1646 | 0.3991 | 0.2481 | 0.0023 | 0.0006 | 0.0053 | 0.0299 | 0.0679 | 0.1066 | 0.0978 | 0.1101 | 0.5796 | 14 | 17 | 23 | 40 | 82 | 156 | 248 | 368 | 533 | 0.0760 | 19.94 | 5.078 | 0.5051 | 85655.4 | 51000000 | 35300000000 | 27300000000000 | 0.6172 | 0.0984 | 0.0318 | 0.0041 | 0.1500 | 0.0191 | 0.2403 | 0.0909 | 0.1748 | 0.1415 | 0.1639 | 0.1829 | 0.1281 | 0.1921 | 0.0616 | 0.1271 | 0.0318 | 0.1054 | 0.0179 | 0.1369 | 0.0002 | 0.0006 | 0.0011 | 0.0010 | 0.0067 | 0.0019 | 0.0132 | 0.0101 | 0.0529 | 0.0477 | 0.1008 | 0.0924 | 0.0697 | 0.0570 | 0.0934 | 0.0891 | 0.6621 | 0.7003 | 0.0014 | 0.0009 | 0.0047 | 0.0046 | 0.0143 | 0.0118 | 0.0201 | 0.0236 | 0.0593 | 0.0611 | 0.1023 | 0.1045 | 0.0662 | 0.0856 | 0.1017 | 0.1135 | 0.6300 | 0.5945 | 0.0005 | 0.0017 | 0.0083 | 0.0225 | 0.0605 | 0.1037 | 0.0722 | 0.0930 | 0.6376 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 153 | 736 | | 17577 | 32431 | 213.5 | 66.22 | 119.98 | 191.83 | 136 | 158 | 175 | 190 | 206 | 224 | 243 | 267 | 300 | 0.0595 | 1929 | 0.787 | 314.94 | 107.02 | 13 | 0.0531 | 934 | 0.0006 | 60.12 | 7.718 | 0.1576 | 49951.2 | 12700000 | 3480000000 | 1030000000000 | 0.4279 | 0.2038 | 0.0008 | 0.0001 | 0.0017 | 0.0000 | 0.0105 | 0.0012 | 0.0391 | 0.0061 | 0.0988 | 0.0278 | 0.1631 | 0.0552 | 0.1671 | 0.0671 | 0.1808 | 0.0927 | 0.3382 | 0.7498 | 0.0004 | 0.0001 | 0.0009 | 0.0000 | 0.0031 | 0.0002 | 0.0119 | 0.0026 | 0.0325 | 0.0130 | 0.0602 | 0.0251 | 0.0610 | 0.0279 | 0.0802 | 0.0411 | 0.7497 | 0.8899 | 0.0021 | 0.0077 | 0.0056 | 0.0131 | 0.0162 | 0.0219 | 0.0440 | 0.0848 | 0.0899 | 0.1297 | 0.1362 | 0.1822 | 0.1144 | 0.1160 | 0.1320 | 0.1510 | 0.4596 | 0.2938 | 0.0007 | 0.0020 | 0.0072 | 0.0280 | 0.0589 | 0.0957 | 0.0855 | 0.1131 | 0.6090 | 12 | 15 | 17 | 19 | 25 | 43 | 91 | 197 | 387 | 0.1336 | 21.39 | 4.248 | 0.6174 | 51191.5 | 32500000 | 25000000000 | 21700000000000 | 0.5704 | 0.1134 | 0.0562 | 0.0029 | 0.1967 | 0.0294 | 0.2199 | 0.1289 | 0.1503 | 0.1471 | 0.1472 | 0.1759 | 0.1038 | 0.1638 | 0.0562 | 0.1096 | 0.0452 | 0.1055 | 0.0244 | 0.1370 | 0.0001 | 0.0003 | 0.0006 | 0.0007 | 0.0023 | 0.0022 | 0.0121 | 0.0103 | 0.0469 | 0.0439 | 0.0761 | 0.0620 | 0.0514 | 0.0494 | 0.0790 | 0.0736 | 0.7315 | 0.7577 | 0.0001 | 0.0003 | 0.0009 | 0.0010 | 0.0024 | 0.0040 | 0.0148 | 0.0174 | 0.0598 | 0.0709 | 0.0992 | 0.1012 | 0.0685 | 0.0794 | 0.1031 | 0.1055 | 0.6513 | 0.6204 | 0.0001 | 0.0002 | 0.0016 | 0.0130 | 0.0555 | 0.0840 | 0.0645 | 0.0934 | 0.6877 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1218 | 150 | | 8328 | 20825 | 278.7 | 60.80 | 290.87 | 439.80 | 204 | 240 | 258 | 272 | 285 | 298 | 311 | 327 | 347 | 0.0520 | 1082 | 0.814 | 131.22 | 25.94 | 2 | 0.0359 | 299 | 0.0015 | 25.68 | 6.861 | 0.2311 | 81369.2 | 24600000 | 7610000000 | 2410000000000 | 0.4056 | 0.2353 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0106 | 0.0006 | 0.0413 | 0.0112 | 0.0811 | 0.0241 | 0.0864 | 0.0135 | 0.1377 | 0.0258 | 0.6381 | 0.9247 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0001 | 0.0143 | 0.0100 | 0.0289 | 0.0185 | 0.0247 | 0.0084 | 0.0466 | 0.0146 | 0.8830 | 0.9483 | 0.0055 | 0.0364 | 0.0234 | 0.0182 | 0.0343 | 0.0455 | 0.0810 | 0.1273 | 0.1262 | 0.1364 | 0.1752 | 0.3091 | 0.1371 | 0.0909 | 0.1269 | 0.0727 | 0.2905 | 0.1636 | 0.0015 | 0.0033 | 0.0074 | 0.0220 | 0.0435 | 0.0863 | 0.0844 | 0.1177 | 0.6340 | 7 | 10 | 13 | 17 | 28 | 115 | 308 | 594 | 1020 | 0.0848 | 69.35 | 5.353 | 0.4886 | 278017.0 | 336000000 | 456000000000 | 669000000000000 | 0.5138 | 0.1645 | 0.0468 | 0.0052 | 0.1680 | 0.0170 | 0.2305 | 0.1168 | 0.1460 | 0.1394 | 0.1433 | 0.1748 | 0.1148 | 0.1667 | 0.0661 | 0.1295 | 0.0487 | 0.1130 | 0.0358 | 0.1375 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0009 | 0.0078 | 0.0073 | 0.0402 | 0.0330 | 0.0717 | 0.0659 | 0.0532 | 0.0476 | 0.0763 | 0.0708 | 0.7497 | 0.7740 | 0.0002 | 0.0011 | 0.0003 | 0.0020 | 0.0034 | 0.0050 | 0.0145 | 0.0131 | 0.0489 | 0.0487 | 0.0799 | 0.0830 | 0.0597 | 0.0625 | 0.0824 | 0.0882 | 0.7106 | 0.6963 | 0.0002 | 0.0002 | 0.0019 | 0.0108 | 0.0438 | 0.0821 | 0.0547 | 0.0780 | 0.7283 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |