High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 736 | 857 | | 16963 | 12738 | 140.2 | 47.70 | 284.47 | 272.42 | 86 | 103 | 115 | 125 | 135 | 146 | 159 | 175 | 199 | 0.1170 | 1490 | 0.454 | 104.36 | 26.02 | 3 | 0.0222 | 376 | 0.0013 | 28.58 | 7.013 | 0.2392 | 21921.8 | 3810000 | 736000000 | 159000000000 | 0.5138 | 0.1429 | 0.0011 | 0.0001 | 0.0046 | 0.0004 | 0.0190 | 0.0015 | 0.0417 | 0.0061 | 0.1096 | 0.0343 | 0.1753 | 0.0705 | 0.1648 | 0.0732 | 0.1725 | 0.1036 | 0.3113 | 0.7103 | 0.0003 | 0.0000 | 0.0016 | 0.0003 | 0.0030 | 0.0006 | 0.0086 | 0.0019 | 0.0379 | 0.0187 | 0.0685 | 0.0336 | 0.0683 | 0.0292 | 0.0917 | 0.0481 | 0.7201 | 0.8674 | 0.0029 | 0.0048 | 0.0072 | 0.0161 | 0.0144 | 0.0353 | 0.0503 | 0.0744 | 0.1120 | 0.1435 | 0.1511 | 0.1879 | 0.1142 | 0.0969 | 0.1336 | 0.1381 | 0.4144 | 0.3030 | 0.0010 | 0.0034 | 0.0085 | 0.0267 | 0.0777 | 0.1103 | 0.0988 | 0.1250 | 0.5485 | 17 | 30 | 70 | 134 | 213 | 299 | 394 | 506 | 659 | 0.0090 | 99.68 | 6.927 | 0.2797 | 155129.0 | 112000000 | 97700000000 | 101000000000000 | 0.5569 | 0.1416 | 0.0517 | 0.0052 | 0.1626 | 0.0189 | 0.2432 | 0.1060 | 0.1736 | 0.1157 | 0.1416 | 0.1826 | 0.1121 | 0.2064 | 0.0622 | 0.1365 | 0.0296 | 0.1148 | 0.0234 | 0.1139 | 0.0003 | 0.0000 | 0.0024 | 0.0010 | 0.0037 | 0.0030 | 0.0161 | 0.0098 | 0.0690 | 0.0611 | 0.1238 | 0.1119 | 0.0809 | 0.0760 | 0.1129 | 0.1040 | 0.5907 | 0.6331 | 0.0007 | 0.0011 | 0.0042 | 0.0032 | 0.0077 | 0.0122 | 0.0247 | 0.0416 | 0.0967 | 0.1108 | 0.1543 | 0.1728 | 0.1062 | 0.1147 | 0.1406 | 0.1433 | 0.4650 | 0.4004 | 0.0008 | 0.0013 | 0.0077 | 0.0199 | 0.0782 | 0.1419 | 0.0914 | 0.1252 | 0.5336 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 183 | | 11039 | 18903 | 371.9 | 102.23 | 380.94 | 449.84 | 242 | 284 | 315 | 342 | 366 | 390 | 419 | 454 | 501 | 0.0627 | 1185 | 0.969 | 171.70 | 54.42 | 2 | 0.0400 | 442 | 0.0005 | 88.34 | 7.910 | 0.1324 | 148751.0 | 63700000 | 29100000000 | 14200000000000 | 0.4490 | 0.2026 | 0.0005 | 0.0000 | 0.0023 | 0.0001 | 0.0082 | 0.0004 | 0.0272 | 0.0029 | 0.0918 | 0.0254 | 0.1600 | 0.0644 | 0.1476 | 0.0628 | 0.1698 | 0.0955 | 0.3925 | 0.7484 | 0.0000 | 0.0000 | 0.0014 | 0.0001 | 0.0014 | 0.0002 | 0.0061 | 0.0012 | 0.0305 | 0.0163 | 0.0618 | 0.0383 | 0.0559 | 0.0283 | 0.0817 | 0.0492 | 0.7612 | 0.8664 | 0.0017 | 0.0049 | 0.0075 | 0.0233 | 0.0200 | 0.0331 | 0.0553 | 0.1129 | 0.1226 | 0.1755 | 0.1816 | 0.1718 | 0.1131 | 0.1055 | 0.1463 | 0.1313 | 0.3520 | 0.2417 | 0.0010 | 0.0019 | 0.0072 | 0.0234 | 0.0705 | 0.1244 | 0.0974 | 0.1322 | 0.5419 | 14 | 21 | 36 | 86 | 184 | 326 | 510 | 738 | 1059 | 0.0281 | 91.44 | 6.434 | 0.3906 | 347456.0 | 416000000 | 584000000000 | 919000000000000 | 0.5129 | 0.1516 | 0.0334 | 0.0012 | 0.1468 | 0.0085 | 0.2688 | 0.0832 | 0.1754 | 0.1376 | 0.1420 | 0.1939 | 0.1025 | 0.2057 | 0.0710 | 0.1331 | 0.0413 | 0.1056 | 0.0188 | 0.1313 | 0.0004 | 0.0001 | 0.0005 | 0.0002 | 0.0010 | 0.0015 | 0.0098 | 0.0078 | 0.0487 | 0.0404 | 0.0789 | 0.0691 | 0.0535 | 0.0457 | 0.0867 | 0.0737 | 0.7204 | 0.7615 | 0.0003 | 0.0002 | 0.0010 | 0.0016 | 0.0018 | 0.0031 | 0.0173 | 0.0236 | 0.0629 | 0.0721 | 0.1053 | 0.1168 | 0.0686 | 0.0778 | 0.1103 | 0.1157 | 0.6324 | 0.5891 | 0.0001 | 0.0003 | 0.0021 | 0.0129 | 0.0563 | 0.0923 | 0.0627 | 0.0991 | 0.6741 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 634 | 828 | | 6200 | 7303 | 203.7 | 43.18 | 209.83 | 149.65 | 154 | 167 | 178 | 188 | 198 | 208 | 221 | 237 | 262 | 0.1191 | 870 | 1.113 | 92.59 | 26.68 | 1 | 0.0353 | 219 | 0.0012 | 41.78 | 7.014 | 0.1838 | 43340.5 | 9650000 | 2250000000 | 547000000000 | 0.4334 | 0.2122 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0003 | 0.0157 | 0.0007 | 0.0711 | 0.0174 | 0.1256 | 0.0376 | 0.1517 | 0.0398 | 0.1830 | 0.0615 | 0.4490 | 0.8428 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0066 | 0.0000 | 0.0335 | 0.0122 | 0.0534 | 0.0229 | 0.0720 | 0.0143 | 0.0964 | 0.0265 | 0.7359 | 0.9239 | 0.0059 | 0.0102 | 0.0088 | 0.0307 | 0.0137 | 0.0648 | 0.0715 | 0.1160 | 0.1538 | 0.1945 | 0.1851 | 0.1672 | 0.1303 | 0.1297 | 0.1538 | 0.1229 | 0.2772 | 0.1638 | 0.0025 | 0.0040 | 0.0087 | 0.0395 | 0.0938 | 0.1242 | 0.1177 | 0.1409 | 0.4687 | 40 | 70 | 103 | 137 | 177 | 225 | 280 | 343 | 426 | 0.0014 | 93.66 | 7.304 | 0.1920 | 66420.4 | 25900000 | 11500000000 | 5580000000000 | 0.5796 | 0.1202 | 0.0390 | 0.0023 | 0.1851 | 0.0148 | 0.2695 | 0.0760 | 0.1802 | 0.1442 | 0.1420 | 0.1832 | 0.1063 | 0.2186 | 0.0446 | 0.1454 | 0.0219 | 0.1134 | 0.0114 | 0.1021 | 0.0005 | 0.0007 | 0.0029 | 0.0009 | 0.0084 | 0.0050 | 0.0260 | 0.0176 | 0.0825 | 0.0686 | 0.1372 | 0.1114 | 0.1075 | 0.0997 | 0.1319 | 0.1233 | 0.5030 | 0.5729 | 0.0019 | 0.0034 | 0.0051 | 0.0059 | 0.0179 | 0.0206 | 0.0451 | 0.0677 | 0.1147 | 0.1290 | 0.1683 | 0.1986 | 0.1306 | 0.1226 | 0.1446 | 0.1466 | 0.3719 | 0.3055 | 0.0003 | 0.0064 | 0.0121 | 0.0359 | 0.0978 | 0.1547 | 0.1134 | 0.1556 | 0.4239 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 615 | 87 | | 3644 | 13644 | 486.1 | 117.15 | 117.91 | 188.35 | 319 | 379 | 428 | 463 | 490 | 516 | 545 | 579 | 629 | 0.0704 | 960 | 0.778 | 78.75 | 25.08 | 2 | 0.0645 | 235 | 0.0008 | 59.20 | 7.366 | 0.1629 | 250045.0 | 135000000 | 76400000000 | 45000000000000 | 0.3808 | 0.2634 | 0.0005 | 0.0003 | 0.0023 | 0.0006 | 0.0065 | 0.0012 | 0.0208 | 0.0024 | 0.0644 | 0.0260 | 0.1185 | 0.0474 | 0.1181 | 0.0477 | 0.1537 | 0.0608 | 0.5153 | 0.8136 | 0.0004 | 0.0003 | 0.0004 | 0.0006 | 0.0025 | 0.0009 | 0.0053 | 0.0017 | 0.0246 | 0.0206 | 0.0421 | 0.0342 | 0.0333 | 0.0284 | 0.0512 | 0.0353 | 0.8404 | 0.8781 | 0.0029 | 0.0165 | 0.0072 | 0.0110 | 0.0435 | 0.0165 | 0.0609 | 0.0824 | 0.1493 | 0.1319 | 0.1493 | 0.1648 | 0.1232 | 0.1044 | 0.1130 | 0.1154 | 0.3507 | 0.3571 | 0.0011 | 0.0005 | 0.0037 | 0.0186 | 0.0541 | 0.0981 | 0.1140 | 0.1352 | 0.5748 | 5 | 7 | 9 | 12 | 18 | 41 | 105 | 209 | 414 | 0.0925 | 12.28 | 4.224 | 0.5614 | 49376.8 | 28700000 | 20000000000 | 16200000000000 | 0.4378 | 0.2206 | 0.0432 | 0.0012 | 0.1512 | 0.0148 | 0.2160 | 0.0598 | 0.1677 | 0.1006 | 0.1423 | 0.1764 | 0.1017 | 0.1795 | 0.0839 | 0.1388 | 0.0597 | 0.1184 | 0.0343 | 0.2104 | 0.0002 | 0.0000 | 0.0007 | 0.0011 | 0.0035 | 0.0013 | 0.0091 | 0.0065 | 0.0424 | 0.0378 | 0.0666 | 0.0551 | 0.0544 | 0.0477 | 0.0811 | 0.0656 | 0.7419 | 0.7849 | 0.0006 | 0.0006 | 0.0023 | 0.0029 | 0.0046 | 0.0048 | 0.0126 | 0.0140 | 0.0584 | 0.0619 | 0.0822 | 0.0909 | 0.0664 | 0.0635 | 0.0908 | 0.0804 | 0.6821 | 0.6810 | 0.0000 | 0.0018 | 0.0028 | 0.0106 | 0.0536 | 0.0732 | 0.0590 | 0.0912 | 0.7077 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1055 | 275 | | 6493 | 11263 | 218.6 | 48.26 | 203.76 | 248.93 | 160 | 175 | 188 | 202 | 213 | 228 | 242 | 260 | 284 | 0.0805 | 907 | 1.214 | 109.13 | 46.40 | 1 | 0.0445 | 289 | 0.0010 | 41.92 | 7.174 | 0.1818 | 50116.4 | 12000000 | 3010000000 | 787000000000 | 0.4497 | 0.2024 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0071 | 0.0008 | 0.0185 | 0.0023 | 0.0843 | 0.0181 | 0.1430 | 0.0392 | 0.1440 | 0.0382 | 0.1793 | 0.0581 | 0.4215 | 0.8433 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0033 | 0.0006 | 0.0078 | 0.0012 | 0.0341 | 0.0120 | 0.0614 | 0.0246 | 0.0581 | 0.0156 | 0.0872 | 0.0283 | 0.7468 | 0.9177 | 0.0041 | 0.0101 | 0.0139 | 0.0270 | 0.0204 | 0.0642 | 0.0736 | 0.1182 | 0.1177 | 0.1959 | 0.1586 | 0.1791 | 0.1267 | 0.1115 | 0.1415 | 0.1149 | 0.3434 | 0.1791 | 0.0013 | 0.0037 | 0.0043 | 0.0266 | 0.0817 | 0.1116 | 0.0986 | 0.1305 | 0.5418 | 15 | 19 | 27 | 46 | 82 | 147 | 253 | 388 | 594 | 0.0226 | 54.69 | 5.986 | 0.4245 | 103479.0 | 70800000 | 56800000000 | 51000000000000 | 0.5176 | 0.1383 | 0.0392 | 0.0017 | 0.1105 | 0.0111 | 0.2280 | 0.0589 | 0.2245 | 0.1100 | 0.1425 | 0.1800 | 0.1140 | 0.2156 | 0.0784 | 0.1367 | 0.0439 | 0.1144 | 0.0190 | 0.1717 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0016 | 0.0012 | 0.0128 | 0.0072 | 0.0372 | 0.0364 | 0.0763 | 0.0706 | 0.0547 | 0.0455 | 0.0772 | 0.0701 | 0.7402 | 0.7678 | 0.0006 | 0.0007 | 0.0006 | 0.0000 | 0.0020 | 0.0030 | 0.0121 | 0.0115 | 0.0506 | 0.0603 | 0.0917 | 0.1121 | 0.0697 | 0.0752 | 0.0975 | 0.1124 | 0.6752 | 0.6248 | 0.0000 | 0.0005 | 0.0018 | 0.0083 | 0.0458 | 0.0871 | 0.0564 | 0.0843 | 0.7159 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1205 | 176 | | 372 | 2800 | 40.2 | 10.05 | 84.88 | 173.91 | 28 | 30 | 34 | 37 | 39 | 41 | 45 | 49 | 53 | 0.1139 | 319 | 0.581 | 191.64 | 52.00 | 2 | 1.5618 | 581 | 0.0086 | 8.20 | 4.933 | 0.3440 | 1713.9 | 77670.5 | 3730000 | 189000000 | 0.3953 | 0.2248 | 0.0051 | 0.0000 | 0.0154 | 0.0000 | 0.0359 | 0.0000 | 0.1333 | 0.0088 | 0.1744 | 0.0821 | 0.1897 | 0.0645 | 0.2154 | 0.1026 | 0.1333 | 0.1378 | 0.0974 | 0.6041 | 0.0036 | 0.0000 | 0.0108 | 0.0000 | 0.0108 | 0.0000 | 0.0502 | 0.0054 | 0.0681 | 0.0622 | 0.0681 | 0.0514 | 0.0968 | 0.0514 | 0.1147 | 0.0784 | 0.5771 | 0.7514 | 0.0000 | 0.0000 | 0.0357 | 0.0345 | 0.1190 | 0.0690 | 0.0238 | 0.2069 | 0.1786 | 0.1379 | 0.1667 | 0.0345 | 0.0952 | 0.2069 | 0.1548 | 0.1379 | 0.2262 | 0.1724 | 0.0056 | 0.0056 | 0.0222 | 0.0444 | 0.0778 | 0.0944 | 0.0889 | 0.1778 | 0.4833 | 15 | 17 | 19 | 21 | 23 | 27 | 32 | 79 | 241 | 0.2089 | 3.35 | 2.782 | 0.7521 | 37440.5 | 29600000 | 28700000000 | 30700000000000 | 0.7152 | 0.0493 | 0.0130 | 0.0061 | 0.1299 | 0.0242 | 0.2987 | 0.0242 | 0.1948 | 0.0848 | 0.1429 | 0.2061 | 0.0779 | 0.2485 | 0.0649 | 0.1333 | 0.0260 | 0.1455 | 0.0519 | 0.1273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0120 | 0.0126 | 0.0342 | 0.0346 | 0.0496 | 0.0362 | 0.0479 | 0.0472 | 0.0803 | 0.0849 | 0.7761 | 0.7799 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0021 | 0.0138 | 0.0085 | 0.0472 | 0.0446 | 0.0591 | 0.0807 | 0.0571 | 0.0573 | 0.1004 | 0.1083 | 0.7185 | 0.6985 | 0.0000 | 0.0000 | 0.0018 | 0.0091 | 0.0453 | 0.0507 | 0.0562 | 0.0888 | 0.7482 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 646 | 630 | | 4918 | 16500 | 250.8 | 54.45 | 183.21 | 159.38 | 187 | 204 | 216 | 230 | 243 | 258 | 275 | 294 | 325 | 0.0553 | 912 | 1.082 | 114.59 | 36.69 | 1 | 0.0567 | 279 | 0.0010 | 47.80 | 7.180 | 0.1740 | 65866.1 | 18100000 | 5220000000 | 1580000000000 | 0.3928 | 0.2565 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0047 | 0.0000 | 0.0187 | 0.0019 | 0.0548 | 0.0194 | 0.1246 | 0.0446 | 0.1390 | 0.0381 | 0.1798 | 0.0538 | 0.4774 | 0.8422 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0081 | 0.0010 | 0.0259 | 0.0120 | 0.0548 | 0.0269 | 0.0577 | 0.0141 | 0.0883 | 0.0210 | 0.7634 | 0.9249 | 0.0059 | 0.0039 | 0.0012 | 0.0116 | 0.0190 | 0.0814 | 0.0853 | 0.1357 | 0.1291 | 0.1667 | 0.1623 | 0.1744 | 0.1232 | 0.1202 | 0.1374 | 0.1279 | 0.3365 | 0.1783 | 0.0009 | 0.0023 | 0.0064 | 0.0273 | 0.0792 | 0.1152 | 0.1184 | 0.1211 | 0.5291 | 18 | 33 | 60 | 103 | 150 | 198 | 247 | 309 | 400 | 0.0089 | 24.20 | 6.264 | 0.3693 | 58965.6 | 24900000 | 12800000000 | 7660000000000 | 0.5028 | 0.1524 | 0.0298 | 0.0012 | 0.1446 | 0.0060 | 0.2626 | 0.0670 | 0.1569 | 0.1200 | 0.1430 | 0.1772 | 0.1184 | 0.1974 | 0.0763 | 0.1242 | 0.0453 | 0.1282 | 0.0230 | 0.1788 | 0.0001 | 0.0000 | 0.0006 | 0.0004 | 0.0025 | 0.0008 | 0.0117 | 0.0094 | 0.0594 | 0.0454 | 0.1105 | 0.0804 | 0.0780 | 0.0631 | 0.1181 | 0.0977 | 0.6190 | 0.7028 | 0.0007 | 0.0013 | 0.0026 | 0.0028 | 0.0058 | 0.0118 | 0.0286 | 0.0350 | 0.0883 | 0.1071 | 0.1510 | 0.1803 | 0.1152 | 0.1150 | 0.1405 | 0.1436 | 0.4674 | 0.4032 | 0.0003 | 0.0018 | 0.0020 | 0.0202 | 0.0756 | 0.1282 | 0.0992 | 0.1368 | 0.5359 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 841 | 100 | | 7377 | 24941 | 386.3 | 96.75 | 88.88 | 190.82 | 262 | 298 | 330 | 360 | 385 | 408 | 433 | 466 | 515 | 0.0500 | 1246 | 0.563 | 94.76 | 26.17 | 2 | 0.0409 | 302 | 0.0008 | 47.55 | 7.415 | 0.1751 | 158588.0 | 68800000 | 31400000000 | 15000000000000 | 0.4311 | 0.2177 | 0.0002 | 0.0000 | 0.0031 | 0.0005 | 0.0070 | 0.0012 | 0.0283 | 0.0041 | 0.0813 | 0.0252 | 0.1505 | 0.0529 | 0.1401 | 0.0558 | 0.1607 | 0.0799 | 0.4286 | 0.7805 | 0.0000 | 0.0000 | 0.0011 | 0.0001 | 0.0023 | 0.0003 | 0.0099 | 0.0018 | 0.0340 | 0.0163 | 0.0593 | 0.0332 | 0.0508 | 0.0272 | 0.0661 | 0.0402 | 0.7764 | 0.8808 | 0.0040 | 0.0130 | 0.0066 | 0.0238 | 0.0139 | 0.0563 | 0.0615 | 0.0909 | 0.1315 | 0.1970 | 0.1606 | 0.1710 | 0.1269 | 0.1255 | 0.1401 | 0.1299 | 0.3549 | 0.1926 | 0.0005 | 0.0014 | 0.0043 | 0.0220 | 0.0674 | 0.1016 | 0.1003 | 0.1272 | 0.5753 | 4 | 5 | 7 | 8 | 10 | 12 | 18 | 103 | 322 | 0.1971 | 13.23 | 3.393 | 0.6457 | 44309.3 | 31100000 | 25500000000 | 23000000000000 | 0.4510 | 0.1554 | 0.0309 | 0.0028 | 0.1373 | 0.0130 | 0.2921 | 0.0763 | 0.2205 | 0.1516 | 0.1431 | 0.2140 | 0.0986 | 0.1898 | 0.0271 | 0.1395 | 0.0213 | 0.1116 | 0.0290 | 0.1014 | 0.0000 | 0.0003 | 0.0009 | 0.0005 | 0.0007 | 0.0016 | 0.0037 | 0.0063 | 0.0213 | 0.0191 | 0.0374 | 0.0318 | 0.0250 | 0.0278 | 0.0407 | 0.0377 | 0.8703 | 0.8748 | 0.0000 | 0.0002 | 0.0008 | 0.0004 | 0.0004 | 0.0019 | 0.0063 | 0.0064 | 0.0259 | 0.0282 | 0.0468 | 0.0526 | 0.0377 | 0.0404 | 0.0539 | 0.0614 | 0.8281 | 0.8084 | 0.0000 | 0.0004 | 0.0008 | 0.0042 | 0.0213 | 0.0423 | 0.0293 | 0.0477 | 0.8540 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 608 | 285 | | 12711 | 40214 | 295.5 | 67.78 | 143.73 | 163.15 | 209 | 239 | 260 | 277 | 293 | 309 | 328 | 350 | 384 | 0.0353 | 1418 | 1.016 | 119.62 | 46.69 | 2 | 0.0271 | 344 | 0.0013 | 26.32 | 6.921 | 0.2277 | 91894.8 | 30000000 | 10200000000 | 3620000000000 | 0.4370 | 0.2187 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0006 | 0.0194 | 0.0020 | 0.0643 | 0.0160 | 0.1388 | 0.0422 | 0.1306 | 0.0429 | 0.1606 | 0.0610 | 0.4809 | 0.8354 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0053 | 0.0011 | 0.0274 | 0.0105 | 0.0590 | 0.0245 | 0.0510 | 0.0194 | 0.0701 | 0.0291 | 0.7861 | 0.9154 | 0.0071 | 0.0128 | 0.0075 | 0.0192 | 0.0179 | 0.0417 | 0.0613 | 0.1330 | 0.1289 | 0.1875 | 0.1811 | 0.2051 | 0.1097 | 0.0865 | 0.1506 | 0.1330 | 0.3358 | 0.1811 | 0.0008 | 0.0024 | 0.0064 | 0.0265 | 0.0750 | 0.1260 | 0.1010 | 0.1299 | 0.5321 | 11 | 17 | 28 | 49 | 80 | 122 | 178 | 254 | 371 | 0.0435 | 17.85 | 5.232 | 0.4864 | 47276.4 | 22300000 | 13100000000 | 8910000000000 | 0.4347 | 0.1843 | 0.0559 | 0.0013 | 0.1725 | 0.0173 | 0.2681 | 0.1183 | 0.1475 | 0.1465 | 0.1431 | 0.1771 | 0.0944 | 0.1809 | 0.0533 | 0.1241 | 0.0376 | 0.1058 | 0.0276 | 0.1288 | 0.0001 | 0.0001 | 0.0004 | 0.0006 | 0.0019 | 0.0015 | 0.0116 | 0.0097 | 0.0649 | 0.0509 | 0.1109 | 0.0898 | 0.0752 | 0.0672 | 0.1098 | 0.0956 | 0.6253 | 0.6846 | 0.0006 | 0.0007 | 0.0011 | 0.0013 | 0.0036 | 0.0075 | 0.0213 | 0.0276 | 0.0840 | 0.0988 | 0.1417 | 0.1531 | 0.0910 | 0.0952 | 0.1254 | 0.1330 | 0.5313 | 0.4828 | 0.0003 | 0.0013 | 0.0032 | 0.0164 | 0.0787 | 0.1225 | 0.0861 | 0.1208 | 0.5707 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 861 | 186 | | 12331 | 15671 | 289.1 | 82.48 | 116.02 | 160.19 | 201 | 225 | 243 | 260 | 276 | 292 | 314 | 345 | 400 | 0.0849 | 1331 | 0.663 | 177.34 | 56.46 | 4 | 0.0431 | 532 | 0.0008 | 58.20 | 7.495 | 0.1717 | 90380.5 | 30600000 | 11200000000 | 4470000000000 | 0.4343 | 0.2144 | 0.0007 | 0.0000 | 0.0013 | 0.0002 | 0.0081 | 0.0007 | 0.0252 | 0.0037 | 0.0800 | 0.0238 | 0.1386 | 0.0531 | 0.1412 | 0.0533 | 0.1670 | 0.0739 | 0.4380 | 0.7912 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0079 | 0.0009 | 0.0344 | 0.0131 | 0.0694 | 0.0240 | 0.0655 | 0.0205 | 0.0934 | 0.0333 | 0.7273 | 0.9081 | 0.0029 | 0.0034 | 0.0074 | 0.0068 | 0.0153 | 0.0316 | 0.0422 | 0.0769 | 0.1071 | 0.1435 | 0.1468 | 0.1973 | 0.1038 | 0.0991 | 0.1443 | 0.1307 | 0.4301 | 0.3108 | 0.0013 | 0.0040 | 0.0106 | 0.0361 | 0.0748 | 0.1272 | 0.0958 | 0.1105 | 0.5396 | 7 | 10 | 13 | 22 | 43 | 73 | 127 | 212 | 335 | 0.0704 | 13.83 | 4.641 | 0.5316 | 39120.6 | 20200000 | 14100000000 | 12400000000000 | 0.5640 | 0.1235 | 0.0406 | 0.0033 | 0.1589 | 0.0200 | 0.2525 | 0.0850 | 0.1954 | 0.1426 | 0.1432 | 0.1904 | 0.1043 | 0.1814 | 0.0579 | 0.1368 | 0.0281 | 0.1111 | 0.0190 | 0.1295 | 0.0000 | 0.0006 | 0.0009 | 0.0012 | 0.0034 | 0.0027 | 0.0101 | 0.0123 | 0.0575 | 0.0454 | 0.0885 | 0.0709 | 0.0600 | 0.0580 | 0.0942 | 0.0801 | 0.6855 | 0.7288 | 0.0002 | 0.0005 | 0.0009 | 0.0015 | 0.0041 | 0.0040 | 0.0175 | 0.0184 | 0.0723 | 0.0875 | 0.1159 | 0.1187 | 0.0771 | 0.0804 | 0.1104 | 0.1200 | 0.6016 | 0.5689 | 0.0000 | 0.0012 | 0.0028 | 0.0153 | 0.0630 | 0.1041 | 0.0675 | 0.1093 | 0.6367 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 656 | 535 | | 6091 | 20546 | 242.4 | 44.53 | 137.26 | 192.39 | 187 | 203 | 216 | 228 | 239 | 251 | 264 | 280 | 303 | 0.0476 | 979 | 1.098 | 86.73 | 30.00 | 1 | 0.0368 | 224 | 0.0009 | 51.40 | 7.200 | 0.1626 | 60738.6 | 15700000 | 4190000000 | 1150000000000 | 0.4279 | 0.2267 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0124 | 0.0005 | 0.0636 | 0.0142 | 0.1292 | 0.0326 | 0.1368 | 0.0323 | 0.1768 | 0.0541 | 0.4789 | 0.8663 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0008 | 0.0000 | 0.0040 | 0.0002 | 0.0280 | 0.0117 | 0.0548 | 0.0216 | 0.0579 | 0.0143 | 0.0777 | 0.0241 | 0.7764 | 0.9281 | 0.0078 | 0.0464 | 0.0056 | 0.0265 | 0.0468 | 0.1126 | 0.1158 | 0.2649 | 0.1815 | 0.2119 | 0.2305 | 0.1854 | 0.1236 | 0.0795 | 0.1336 | 0.0530 | 0.1548 | 0.0199 | 0.0003 | 0.0010 | 0.0075 | 0.0369 | 0.0799 | 0.1438 | 0.1237 | 0.1565 | 0.4503 | 10 | 11 | 13 | 16 | 25 | 62 | 149 | 281 | 445 | 0.1040 | 21.77 | 4.771 | 0.5558 | 55854.0 | 29600000 | 17800000000 | 11700000000000 | 0.5221 | 0.1170 | 0.0474 | 0.0028 | 0.1966 | 0.0109 | 0.3034 | 0.1095 | 0.1798 | 0.1664 | 0.1433 | 0.2227 | 0.0870 | 0.1986 | 0.0267 | 0.1227 | 0.0128 | 0.0858 | 0.0030 | 0.0806 | 0.0003 | 0.0003 | 0.0009 | 0.0003 | 0.0017 | 0.0020 | 0.0094 | 0.0084 | 0.0422 | 0.0385 | 0.0682 | 0.0630 | 0.0444 | 0.0432 | 0.0669 | 0.0635 | 0.7660 | 0.7808 | 0.0002 | 0.0002 | 0.0002 | 0.0009 | 0.0014 | 0.0024 | 0.0088 | 0.0122 | 0.0505 | 0.0500 | 0.0741 | 0.0794 | 0.0549 | 0.0568 | 0.0763 | 0.0835 | 0.7338 | 0.7146 | 0.0005 | 0.0006 | 0.0024 | 0.0080 | 0.0436 | 0.0706 | 0.0510 | 0.0733 | 0.7499 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1218 | 150 | | 8328 | 20825 | 278.7 | 60.80 | 290.87 | 439.80 | 204 | 240 | 258 | 272 | 285 | 298 | 311 | 327 | 347 | 0.0520 | 1082 | 0.814 | 131.22 | 25.94 | 2 | 0.0359 | 299 | 0.0015 | 25.68 | 6.861 | 0.2311 | 81369.2 | 24600000 | 7610000000 | 2410000000000 | 0.4056 | 0.2353 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0106 | 0.0006 | 0.0413 | 0.0112 | 0.0811 | 0.0241 | 0.0864 | 0.0135 | 0.1377 | 0.0258 | 0.6381 | 0.9247 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0001 | 0.0143 | 0.0100 | 0.0289 | 0.0185 | 0.0247 | 0.0084 | 0.0466 | 0.0146 | 0.8830 | 0.9483 | 0.0055 | 0.0364 | 0.0234 | 0.0182 | 0.0343 | 0.0455 | 0.0810 | 0.1273 | 0.1262 | 0.1364 | 0.1752 | 0.3091 | 0.1371 | 0.0909 | 0.1269 | 0.0727 | 0.2905 | 0.1636 | 0.0015 | 0.0033 | 0.0074 | 0.0220 | 0.0435 | 0.0863 | 0.0844 | 0.1177 | 0.6340 | 7 | 10 | 13 | 17 | 28 | 115 | 308 | 594 | 1020 | 0.0848 | 69.35 | 5.353 | 0.4886 | 278017.0 | 336000000 | 456000000000 | 669000000000000 | 0.5138 | 0.1645 | 0.0468 | 0.0052 | 0.1680 | 0.0170 | 0.2305 | 0.1168 | 0.1460 | 0.1394 | 0.1433 | 0.1748 | 0.1148 | 0.1667 | 0.0661 | 0.1295 | 0.0487 | 0.1130 | 0.0358 | 0.1375 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0009 | 0.0078 | 0.0073 | 0.0402 | 0.0330 | 0.0717 | 0.0659 | 0.0532 | 0.0476 | 0.0763 | 0.0708 | 0.7497 | 0.7740 | 0.0002 | 0.0011 | 0.0003 | 0.0020 | 0.0034 | 0.0050 | 0.0145 | 0.0131 | 0.0489 | 0.0487 | 0.0799 | 0.0830 | 0.0597 | 0.0625 | 0.0824 | 0.0882 | 0.7106 | 0.6963 | 0.0002 | 0.0002 | 0.0019 | 0.0108 | 0.0438 | 0.0821 | 0.0547 | 0.0780 | 0.7283 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 652 | 166 | | 1359 | 6119 | 428.9 | 60.31 | 32.37 | 70.62 | 351 | 373 | 390 | 405 | 426 | 446 | 465 | 483 | 508 | 0.0709 | 434 | 0.794 | 97.08 | 19.70 | 1 | 0.1670 | 227 | 0.0023 | 22.07 | 6.272 | 0.2405 | 187585.0 | 83600000 | 38000000000 | 17500000000000 | 0.4204 | 0.2216 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0061 | 0.0000 | 0.0462 | 0.0221 | 0.0688 | 0.0324 | 0.0592 | 0.0191 | 0.0897 | 0.0316 | 0.7265 | 0.8948 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0016 | 0.0000 | 0.0293 | 0.0221 | 0.0443 | 0.0324 | 0.0332 | 0.0191 | 0.0546 | 0.0316 | 0.8347 | 0.8948 | 0.0259 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0776 | 0.0000 | 0.1638 | 0.0000 | 0.1983 | 0.0000 | 0.1207 | 0.0000 | 0.1379 | 0.0000 | 0.2759 | 0.0000 | 0.0000 | 0.0046 | 0.0077 | 0.0107 | 0.0475 | 0.0644 | 0.0706 | 0.0982 | 0.6963 | 6 | 8 | 9 | 10 | 11 | 13 | 15 | 23 | 79 | 0.3514 | 3.58 | 2.313 | 0.8106 | 6034.5 | 2460000 | 1350000000 | 863000000000 | 0.6003 | 0.1052 | 0.0807 | 0.0227 | 0.0807 | 0.0644 | 0.1211 | 0.0814 | 0.2870 | 0.1458 | 0.1435 | 0.1496 | 0.1480 | 0.1458 | 0.0762 | 0.1326 | 0.0583 | 0.1307 | 0.0045 | 0.1269 | 0.0088 | 0.0079 | 0.0044 | 0.0186 | 0.0071 | 0.0193 | 0.0274 | 0.0336 | 0.0398 | 0.0480 | 0.0548 | 0.0523 | 0.0610 | 0.0651 | 0.0839 | 0.0938 | 0.7129 | 0.6614 | 0.0000 | 0.0000 | 0.0044 | 0.0023 | 0.0055 | 0.0046 | 0.0143 | 0.0161 | 0.0539 | 0.0506 | 0.0462 | 0.0598 | 0.0616 | 0.0529 | 0.0935 | 0.0978 | 0.7206 | 0.7158 | 0.0020 | 0.0050 | 0.0090 | 0.0160 | 0.0548 | 0.0439 | 0.0499 | 0.1017 | 0.7178 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 916 | 208 | | 6312 | 22401 | 516.6 | 108.92 | 194.68 | 249.60 | 387 | 432 | 460 | 485 | 506 | 529 | 554 | 590 | 659 | 0.0487 | 1092 | 1.116 | 137.30 | 45.69 | 1 | 0.0535 | 338 | 0.0007 | 69.42 | 7.543 | 0.1440 | 278766.0 | 157000000 | 92800000000 | 57400000000000 | 0.4428 | 0.2109 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0104 | 0.0019 | 0.0576 | 0.0179 | 0.1165 | 0.0397 | 0.1247 | 0.0358 | 0.1680 | 0.0608 | 0.5208 | 0.8440 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0008 | 0.0320 | 0.0120 | 0.0592 | 0.0239 | 0.0665 | 0.0194 | 0.0912 | 0.0340 | 0.7446 | 0.9099 | 0.0077 | 0.0096 | 0.0132 | 0.0096 | 0.0252 | 0.0382 | 0.0614 | 0.0669 | 0.1107 | 0.1369 | 0.1590 | 0.2452 | 0.0998 | 0.1051 | 0.1239 | 0.1624 | 0.3991 | 0.2261 | 0.0021 | 0.0045 | 0.0156 | 0.0403 | 0.0904 | 0.1255 | 0.1172 | 0.1321 | 0.4722 | 8 | 11 | 15 | 29 | 79 | 153 | 245 | 373 | 559 | 0.0687 | 42.39 | 5.505 | 0.4513 | 100197.0 | 70500000 | 59900000000 | 58200000000000 | 0.4609 | 0.1681 | 0.0552 | 0.0013 | 0.1678 | 0.0137 | 0.2533 | 0.1058 | 0.1683 | 0.1355 | 0.1438 | 0.1985 | 0.1037 | 0.1961 | 0.0500 | 0.1334 | 0.0302 | 0.1063 | 0.0276 | 0.1095 | 0.0003 | 0.0001 | 0.0002 | 0.0003 | 0.0016 | 0.0011 | 0.0067 | 0.0064 | 0.0528 | 0.0424 | 0.0871 | 0.0742 | 0.0642 | 0.0559 | 0.0943 | 0.0845 | 0.6926 | 0.7352 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0026 | 0.0047 | 0.0182 | 0.0210 | 0.0633 | 0.0712 | 0.1119 | 0.1303 | 0.0840 | 0.0811 | 0.1128 | 0.1143 | 0.6064 | 0.5764 | 0.0003 | 0.0010 | 0.0028 | 0.0120 | 0.0577 | 0.0977 | 0.0730 | 0.1042 | 0.6513 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 566 | 807 | | 4751 | 7725 | 404.9 | 192.17 | 127.70 | 196.98 | 142 | 186 | 268 | 341 | 396 | 464 | 540 | 611 | 670 | 0.1111 | 858 | 1.078 | 54.04 | 18.87 | 1 | 0.0280 | 133 | 0.0027 | 8.16 | 6.352 | 0.3795 | 200834.0 | 112000000 | 66500000000 | 41200000000000 | 0.3420 | 0.2744 | 0.0000 | 0.0005 | 0.0008 | 0.0005 | 0.0016 | 0.0005 | 0.0219 | 0.0064 | 0.0926 | 0.0401 | 0.1300 | 0.0724 | 0.1024 | 0.0519 | 0.1446 | 0.0738 | 0.5061 | 0.7540 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0003 | 0.0189 | 0.0153 | 0.0314 | 0.0269 | 0.0245 | 0.0136 | 0.0453 | 0.0266 | 0.8762 | 0.9173 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0011 | 0.0008 | 0.0050 | 0.0111 | 0.0296 | 0.0325 | 0.0369 | 0.0507 | 0.0335 | 0.0428 | 0.0464 | 0.0642 | 0.8475 | 0.7971 | 0.0000 | 0.0004 | 0.0000 | 0.0104 | 0.0265 | 0.0370 | 0.0313 | 0.0487 | 0.8456 | 7 | 9 | 11 | 16 | 28 | 63 | 121 | 222 | 412 | 0.0706 | 13.58 | 4.145 | 0.5200 | 55103.2 | 34600000 | 26500000000 | 23100000000000 | 0.6752 | 0.0630 | 0.0314 | 0.0009 | 0.1458 | 0.0204 | 0.2288 | 0.0814 | 0.1513 | 0.1230 | 0.1439 | 0.1748 | 0.1328 | 0.1832 | 0.0627 | 0.1221 | 0.0424 | 0.1240 | 0.0609 | 0.1702 | 0.0008 | 0.0000 | 0.0008 | 0.0003 | 0.0020 | 0.0007 | 0.0106 | 0.0115 | 0.0701 | 0.0687 | 0.1133 | 0.0965 | 0.0830 | 0.0767 | 0.1251 | 0.1154 | 0.5943 | 0.6302 | 0.0015 | 0.0000 | 0.0035 | 0.0028 | 0.0095 | 0.0084 | 0.0160 | 0.0302 | 0.0845 | 0.0878 | 0.1191 | 0.1270 | 0.1046 | 0.1079 | 0.1251 | 0.1208 | 0.5363 | 0.5151 | 0.0000 | 0.0013 | 0.0013 | 0.0191 | 0.0756 | 0.1250 | 0.0894 | 0.1299 | 0.5583 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 963 | 51 | | 463 | 2383 | 135.5 | 54.95 | 285.62 | 357.76 | 57 | 79 | 96 | 118 | 140 | 159 | 176 | 191 | 206 | 0.1389 | 331 | 0.806 | 83.49 | 17.80 | 1 | 0.4125 | 191 | 0.0030 | 40.37 | 5.894 | 0.2035 | 21382.7 | 3690000 | 675000000 | 128000000000 | 0.3277 | 0.2693 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0794 | 0.0000 | 0.2063 | 0.0037 | 0.3016 | 0.0967 | 0.2381 | 0.2528 | 0.0952 | 0.1413 | 0.0635 | 0.1450 | 0.0159 | 0.3606 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0066 | 0.0027 | 0.0459 | 0.0495 | 0.1180 | 0.1016 | 0.0525 | 0.0330 | 0.0721 | 0.0549 | 0.7049 | 0.7582 | 0.0000 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0000 | 0.0168 | 0.0947 | 0.0726 | 0.1053 | 0.2123 | 0.2947 | 0.0894 | 0.0526 | 0.1285 | 0.1053 | 0.4804 | 0.3368 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0664 | 0.1286 | 0.0747 | 0.1079 | 0.6100 | 17 | 24 | 32 | 51 | 103 | 203 | 340 | 571 | 860 | 0.0209 | 106.06 | 5.674 | 0.3655 | 209519.0 | 201000000 | 220000000000 | 261000000000000 | 0.5461 | 0.1235 | 0.1000 | 0.0053 | 0.1944 | 0.0317 | 0.2833 | 0.1504 | 0.1389 | 0.1926 | 0.1444 | 0.1636 | 0.0833 | 0.1900 | 0.0444 | 0.0765 | 0.0056 | 0.1187 | 0.0056 | 0.0712 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0169 | 0.0137 | 0.0349 | 0.0235 | 0.0992 | 0.0832 | 0.1680 | 0.1566 | 0.0891 | 0.0861 | 0.1184 | 0.1252 | 0.4724 | 0.5117 | 0.0057 | 0.0016 | 0.0127 | 0.0109 | 0.0255 | 0.0264 | 0.0368 | 0.0358 | 0.0990 | 0.0995 | 0.1457 | 0.1384 | 0.0905 | 0.1151 | 0.1132 | 0.1073 | 0.4710 | 0.4650 | 0.0012 | 0.0037 | 0.0224 | 0.0387 | 0.1110 | 0.1459 | 0.1010 | 0.1035 | 0.4726 | ||
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 980 | 154 | | 9107 | 15265 | 478.7 | 85.92 | 198.56 | 276.33 | 358 | 401 | 437 | 463 | 485 | 506 | 527 | 552 | 588 | 0.0735 | 1122 | 0.982 | 84.40 | 29.43 | 4 | 0.0254 | 231 | 0.0010 | 22.23 | 7.221 | 0.2396 | 236580.0 | 120000000 | 62600000000 | 33300000000000 | 0.4434 | 0.2060 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0001 | 0.0113 | 0.0006 | 0.0270 | 0.0119 | 0.0415 | 0.0194 | 0.0463 | 0.0139 | 0.0694 | 0.0222 | 0.7980 | 0.9319 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0000 | 0.0040 | 0.0006 | 0.0131 | 0.0117 | 0.0209 | 0.0179 | 0.0208 | 0.0114 | 0.0297 | 0.0180 | 0.9101 | 0.9405 | 0.0083 | 0.0294 | 0.0173 | 0.0588 | 0.0273 | 0.0882 | 0.0380 | 0.2059 | 0.0512 | 0.2353 | 0.0760 | 0.1471 | 0.0950 | 0.1471 | 0.1230 | 0.0588 | 0.5640 | 0.0294 | 0.0010 | 0.0031 | 0.0072 | 0.0149 | 0.0256 | 0.0345 | 0.0450 | 0.0565 | 0.8122 | 11 | 14 | 19 | 34 | 73 | 133 | 224 | 349 | 565 | 0.0491 | 47.73 | 5.568 | 0.4783 | 115779.0 | 101000000 | 112000000000 | 147000000000000 | 0.3844 | 0.2395 | 0.0410 | 0.0015 | 0.1640 | 0.0173 | 0.2243 | 0.0857 | 0.1640 | 0.1357 | 0.1446 | 0.1765 | 0.1106 | 0.1922 | 0.0789 | 0.1361 | 0.0472 | 0.1023 | 0.0255 | 0.1526 | 0.0004 | 0.0003 | 0.0011 | 0.0014 | 0.0023 | 0.0048 | 0.0151 | 0.0114 | 0.0519 | 0.0457 | 0.0774 | 0.0628 | 0.0614 | 0.0517 | 0.0854 | 0.0750 | 0.7052 | 0.7469 | 0.0002 | 0.0005 | 0.0018 | 0.0031 | 0.0067 | 0.0089 | 0.0220 | 0.0270 | 0.0687 | 0.0786 | 0.1061 | 0.1226 | 0.0859 | 0.0881 | 0.1079 | 0.1098 | 0.6006 | 0.5613 | 0.0004 | 0.0012 | 0.0052 | 0.0181 | 0.0596 | 0.0890 | 0.0721 | 0.1031 | 0.6512 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 279 | 429 | | 995 | 12586 | 70.7 | 14.90 | 155.58 | 186.93 | 55 | 59 | 63 | 66 | 69 | 72 | 76 | 81 | 90 | 0.0678 | 853 | 0.399 | 137.53 | 31.00 | 1 | 0.5668 | 564 | 0.0090 | 7.28 | 5.031 | 0.3913 | 5218.8 | 403150 | 32700000 | 2780000000 | 0.5290 | 0.1303 | 0.0014 | 0.0000 | 0.0041 | 0.0000 | 0.0218 | 0.0032 | 0.0476 | 0.0139 | 0.1252 | 0.0586 | 0.1823 | 0.1471 | 0.1469 | 0.0768 | 0.1524 | 0.1333 | 0.3184 | 0.5672 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0020 | 0.0207 | 0.0061 | 0.0794 | 0.0499 | 0.1427 | 0.1314 | 0.0863 | 0.0540 | 0.1116 | 0.0967 | 0.5524 | 0.6599 | 0.0149 | 0.0455 | 0.0149 | 0.0000 | 0.0522 | 0.1136 | 0.1343 | 0.1136 | 0.2015 | 0.2955 | 0.2015 | 0.2045 | 0.1119 | 0.0227 | 0.1269 | 0.1818 | 0.1418 | 0.0227 | 0.0068 | 0.0158 | 0.0158 | 0.0813 | 0.1512 | 0.1558 | 0.1129 | 0.1490 | 0.3115 | 16 | 20 | 30 | 53 | 84 | 116 | 167 | 264 | 418 | 0.0235 | 46.09 | 5.759 | 0.4355 | 59144.7 | 33000000 | 22700000000 | 17700000000000 | 0.5490 | 0.1235 | 0.0353 | 0.0025 | 0.1470 | 0.0151 | 0.2292 | 0.0792 | 0.1425 | 0.1235 | 0.1447 | 0.1704 | 0.1190 | 0.1746 | 0.0816 | 0.1179 | 0.0654 | 0.1193 | 0.0353 | 0.1975 | 0.0004 | 0.0007 | 0.0004 | 0.0019 | 0.0042 | 0.0029 | 0.0129 | 0.0102 | 0.0601 | 0.0507 | 0.1106 | 0.0865 | 0.0811 | 0.0676 | 0.1162 | 0.1025 | 0.6141 | 0.6771 | 0.0009 | 0.0010 | 0.0023 | 0.0017 | 0.0032 | 0.0023 | 0.0227 | 0.0252 | 0.0827 | 0.1026 | 0.1474 | 0.1437 | 0.0903 | 0.1010 | 0.1282 | 0.1400 | 0.5223 | 0.4826 | 0.0002 | 0.0015 | 0.0037 | 0.0187 | 0.0791 | 0.1231 | 0.0843 | 0.1271 | 0.5622 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 717 | 772 | | 5044 | 13779 | 301.7 | 59.20 | 210.76 | 220.75 | 231 | 249 | 265 | 280 | 295 | 312 | 331 | 354 | 385 | 0.0589 | 812 | 0.776 | 118.60 | 32.65 | 1 | 0.0632 | 319 | 0.0007 | 72.96 | 7.469 | 0.1451 | 94502.0 | 30700000 | 10300000000 | 3580000000000 | 0.4636 | 0.1931 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0000 | 0.0145 | 0.0006 | 0.0751 | 0.0121 | 0.1252 | 0.0311 | 0.1304 | 0.0313 | 0.1693 | 0.0459 | 0.4797 | 0.8791 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0044 | 0.0000 | 0.0323 | 0.0096 | 0.0650 | 0.0212 | 0.0617 | 0.0156 | 0.0939 | 0.0258 | 0.7425 | 0.9278 | 0.0060 | 0.0074 | 0.0072 | 0.0148 | 0.0241 | 0.0889 | 0.0869 | 0.1778 | 0.1351 | 0.1926 | 0.1966 | 0.2296 | 0.1230 | 0.1037 | 0.1460 | 0.1185 | 0.2750 | 0.0667 | 0.0004 | 0.0009 | 0.0051 | 0.0381 | 0.0908 | 0.1422 | 0.0934 | 0.1285 | 0.5004 | 12 | 16 | 29 | 71 | 138 | 216 | 302 | 388 | 517 | 0.0184 | 66.02 | 6.381 | 0.3575 | 93147.7 | 54300000 | 38200000000 | 31100000000000 | 0.5593 | 0.0982 | 0.0360 | 0.0028 | 0.1517 | 0.0183 | 0.2992 | 0.0785 | 0.1891 | 0.1391 | 0.1447 | 0.1813 | 0.0976 | 0.2120 | 0.0429 | 0.1411 | 0.0277 | 0.1141 | 0.0111 | 0.1128 | 0.0005 | 0.0000 | 0.0006 | 0.0013 | 0.0024 | 0.0029 | 0.0090 | 0.0067 | 0.0485 | 0.0391 | 0.0883 | 0.0705 | 0.0680 | 0.0561 | 0.1104 | 0.0882 | 0.6724 | 0.7352 | 0.0002 | 0.0007 | 0.0010 | 0.0007 | 0.0043 | 0.0064 | 0.0151 | 0.0203 | 0.0661 | 0.0835 | 0.1350 | 0.1546 | 0.0965 | 0.1018 | 0.1321 | 0.1450 | 0.5497 | 0.4870 | 0.0002 | 0.0009 | 0.0032 | 0.0112 | 0.0580 | 0.1055 | 0.0852 | 0.1259 | 0.6100 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1097 | 401 | | 5619 | 10511 | 100.4 | 25.69 | 150.94 | 167.26 | 71 | 79 | 86 | 92 | 97 | 103 | 110 | 119 | 132 | 0.0786 | 826 | 0.983 | 96.05 | 27.31 | 1 | 0.0418 | 235 | 0.0033 | 15.27 | 6.069 | 0.2967 | 10734.1 | 1230000 | 151000000 | 19900000000 | 0.4514 | 0.2026 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0093 | 0.0000 | 0.0335 | 0.0025 | 0.0924 | 0.0231 | 0.1475 | 0.0450 | 0.1673 | 0.0550 | 0.1991 | 0.0865 | 0.3487 | 0.7879 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0000 | 0.0089 | 0.0002 | 0.0392 | 0.0149 | 0.0643 | 0.0223 | 0.0770 | 0.0225 | 0.1061 | 0.0415 | 0.7020 | 0.8987 | 0.0103 | 0.0074 | 0.0197 | 0.0245 | 0.0310 | 0.0515 | 0.0874 | 0.0711 | 0.1400 | 0.1985 | 0.1805 | 0.1642 | 0.1184 | 0.1201 | 0.1391 | 0.1569 | 0.2735 | 0.2059 | 0.0012 | 0.0051 | 0.0125 | 0.0446 | 0.0896 | 0.1405 | 0.1151 | 0.1526 | 0.4387 | 11 | 17 | 32 | 53 | 79 | 117 | 181 | 290 | 415 | 0.0097 | 71.41 | 6.470 | 0.3608 | 50757.6 | 22700000 | 11700000000 | 6580000000000 | 0.5255 | 0.1681 | 0.0205 | 0.0024 | 0.1212 | 0.0122 | 0.2269 | 0.0538 | 0.1561 | 0.1204 | 0.1448 | 0.1703 | 0.1458 | 0.1689 | 0.0791 | 0.1385 | 0.0565 | 0.1434 | 0.0493 | 0.1899 | 0.0005 | 0.0004 | 0.0015 | 0.0008 | 0.0056 | 0.0018 | 0.0121 | 0.0135 | 0.0522 | 0.0488 | 0.0869 | 0.0725 | 0.0689 | 0.0674 | 0.0959 | 0.0926 | 0.6765 | 0.7021 | 0.0000 | 0.0007 | 0.0022 | 0.0011 | 0.0060 | 0.0049 | 0.0133 | 0.0226 | 0.0616 | 0.0560 | 0.1042 | 0.1173 | 0.0801 | 0.0920 | 0.1087 | 0.1117 | 0.6238 | 0.5937 | 0.0014 | 0.0025 | 0.0061 | 0.0150 | 0.0574 | 0.0872 | 0.0738 | 0.0955 | 0.6611 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1189 | 718 | | 4088 | 19318 | 453.0 | 106.58 | 96.23 | 99.59 | 325 | 357 | 386 | 412 | 441 | 469 | 504 | 546 | 607 | 0.0500 | 965 | 1.115 | 111.23 | 32.65 | 1 | 0.0624 | 255 | 0.0007 | 67.51 | 7.409 | 0.1424 | 216555.0 | 109000000 | 57400000000 | 31500000000000 | 0.4176 | 0.2368 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0042 | 0.0003 | 0.0275 | 0.0040 | 0.0803 | 0.0242 | 0.1695 | 0.0594 | 0.1357 | 0.0548 | 0.1682 | 0.0698 | 0.4134 | 0.7875 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0100 | 0.0017 | 0.0344 | 0.0160 | 0.0821 | 0.0397 | 0.0581 | 0.0242 | 0.0865 | 0.0410 | 0.7264 | 0.8774 | 0.0012 | 0.0071 | 0.0084 | 0.0000 | 0.0096 | 0.0249 | 0.0646 | 0.1068 | 0.0969 | 0.1459 | 0.1352 | 0.1851 | 0.1172 | 0.1281 | 0.1148 | 0.1637 | 0.4522 | 0.2384 | 0.0016 | 0.0043 | 0.0070 | 0.0290 | 0.0774 | 0.1198 | 0.0956 | 0.1263 | 0.5390 | 8 | 11 | 16 | 33 | 63 | 99 | 134 | 174 | 230 | 0.0320 | 16.16 | 5.428 | 0.4394 | 19177.9 | 5220000 | 1780000000 | 719000000000 | 0.4849 | 0.1488 | 0.0329 | 0.0012 | 0.1667 | 0.0102 | 0.2528 | 0.0730 | 0.1924 | 0.1400 | 0.1450 | 0.1900 | 0.1015 | 0.2083 | 0.0551 | 0.1299 | 0.0343 | 0.1220 | 0.0193 | 0.1254 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0020 | 0.0012 | 0.0104 | 0.0077 | 0.0520 | 0.0427 | 0.0878 | 0.0780 | 0.0668 | 0.0541 | 0.0945 | 0.0813 | 0.6857 | 0.7349 | 0.0007 | 0.0007 | 0.0022 | 0.0028 | 0.0048 | 0.0102 | 0.0188 | 0.0254 | 0.0667 | 0.0816 | 0.1172 | 0.1331 | 0.0893 | 0.0932 | 0.1224 | 0.1264 | 0.5778 | 0.5265 | 0.0004 | 0.0004 | 0.0035 | 0.0151 | 0.0545 | 0.1053 | 0.0729 | 0.1062 | 0.6416 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 927 | 887 | | 3637 | 16754 | 208.9 | 92.53 | 65.01 | 116.76 | 121 | 135 | 144 | 158 | 179 | 205 | 235 | 270 | 358 | 0.0556 | 932 | 0.834 | 150.33 | 54.74 | 2 | 0.1270 | 462 | 0.0037 | 12.92 | 6.141 | 0.3836 | 52205.7 | 15500000 | 5250000000 | 1970000000000 | 0.4763 | 0.1819 | 0.0019 | 0.0015 | 0.0029 | 0.0023 | 0.0229 | 0.0034 | 0.0381 | 0.0138 | 0.0705 | 0.0356 | 0.0896 | 0.0521 | 0.0925 | 0.0502 | 0.1211 | 0.0705 | 0.5605 | 0.7705 | 0.0010 | 0.0013 | 0.0010 | 0.0016 | 0.0050 | 0.0022 | 0.0076 | 0.0094 | 0.0222 | 0.0216 | 0.0443 | 0.0388 | 0.0267 | 0.0297 | 0.0489 | 0.0503 | 0.8433 | 0.8452 | 0.0021 | 0.0000 | 0.0011 | 0.0068 | 0.0064 | 0.0034 | 0.0139 | 0.0051 | 0.0502 | 0.0425 | 0.0694 | 0.0969 | 0.0491 | 0.0459 | 0.0780 | 0.0986 | 0.7297 | 0.7007 | 0.0014 | 0.0021 | 0.0014 | 0.0057 | 0.0291 | 0.0704 | 0.0455 | 0.0824 | 0.7619 | 5 | 7 | 8 | 10 | 13 | 21 | 44 | 90 | 198 | 0.1255 | 5.70 | 3.389 | 0.6022 | 17857.4 | 7770000 | 4140000000 | 2500000000000 | 0.4976 | 0.1519 | 0.0344 | 0.0046 | 0.1527 | 0.0207 | 0.2796 | 0.0718 | 0.1989 | 0.1314 | 0.1452 | 0.1840 | 0.0882 | 0.2058 | 0.0527 | 0.1436 | 0.0312 | 0.1193 | 0.0172 | 0.1188 | 0.0002 | 0.0009 | 0.0019 | 0.0019 | 0.0043 | 0.0024 | 0.0143 | 0.0145 | 0.0517 | 0.0443 | 0.0853 | 0.0765 | 0.0530 | 0.0575 | 0.0866 | 0.0815 | 0.7027 | 0.7204 | 0.0003 | 0.0012 | 0.0024 | 0.0039 | 0.0053 | 0.0051 | 0.0173 | 0.0170 | 0.0587 | 0.0670 | 0.1025 | 0.1053 | 0.0672 | 0.0804 | 0.1014 | 0.1071 | 0.6449 | 0.6130 | 0.0012 | 0.0022 | 0.0050 | 0.0146 | 0.0566 | 0.0853 | 0.0609 | 0.1035 | 0.6707 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 284 | 471 | | 1555 | 4253 | 401.1 | 47.90 | 19.31 | 18.63 | 332 | 364 | 381 | 394 | 406 | 416 | 429 | 441 | 459 | 0.0997 | 424 | 1.147 | 61.20 | 22.02 | 1 | 0.1016 | 158 | 0.0027 | 20.18 | 6.139 | 0.2451 | 163138.0 | 67200000 | 28000000000 | 11800000000000 | 0.4443 | 0.1979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0006 | 0.0285 | 0.0239 | 0.0463 | 0.0303 | 0.0484 | 0.0232 | 0.0855 | 0.0342 | 0.7877 | 0.8877 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0006 | 0.0241 | 0.0239 | 0.0345 | 0.0303 | 0.0241 | 0.0232 | 0.0427 | 0.0342 | 0.8711 | 0.8877 | 0.0426 | 0.0000 | 0.1064 | 0.0000 | 0.1064 | 0.0000 | 0.1277 | 0.0000 | 0.2340 | 0.0000 | 0.1702 | 0.0000 | 0.0638 | 0.0000 | 0.1064 | 0.0000 | 0.0426 | 0.0000 | 0.0000 | 0.0060 | 0.0072 | 0.0358 | 0.0656 | 0.1144 | 0.1085 | 0.1323 | 0.5304 | 8 | 10 | 11 | 13 | 14 | 16 | 18 | 23 | 33 | 0.2369 | 0.56 | 2.092 | 0.8275 | 719.8 | 57928.3 | 7540000 | 1230000000 | 0.5877 | 0.1129 | 0.1023 | 0.0171 | 0.1338 | 0.0274 | 0.1250 | 0.0499 | 0.1439 | 0.0846 | 0.1452 | 0.1170 | 0.1351 | 0.1471 | 0.1225 | 0.1498 | 0.0682 | 0.1619 | 0.0240 | 0.2452 | 0.0447 | 0.0107 | 0.0494 | 0.0169 | 0.0353 | 0.0331 | 0.0358 | 0.0562 | 0.0529 | 0.0841 | 0.0764 | 0.1041 | 0.0781 | 0.1013 | 0.1193 | 0.1162 | 0.5082 | 0.4774 | 0.0132 | 0.0162 | 0.0154 | 0.0310 | 0.0209 | 0.0398 | 0.0473 | 0.0516 | 0.0780 | 0.0634 | 0.0978 | 0.1165 | 0.1022 | 0.0870 | 0.1516 | 0.1608 | 0.4736 | 0.4336 | 0.0277 | 0.0317 | 0.0222 | 0.0301 | 0.0586 | 0.0705 | 0.0777 | 0.1474 | 0.5341 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1098 | 245 | | 11985 | 25048 | 84.9 | 24.68 | 210.46 | 174.39 | 57 | 66 | 72 | 78 | 83 | 89 | 96 | 104 | 117 | 0.0493 | 1235 | 1.212 | 170.77 | 60.46 | 3 | 0.0339 | 406 | 0.0035 | 11.99 | 6.022 | 0.3238 | 7822.1 | 773291 | 81600000 | 9180000000 | 0.4646 | 0.2016 | 0.0015 | 0.0001 | 0.0035 | 0.0002 | 0.0189 | 0.0013 | 0.0497 | 0.0060 | 0.0986 | 0.0268 | 0.1577 | 0.0599 | 0.1701 | 0.0693 | 0.1916 | 0.1035 | 0.3083 | 0.7329 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0039 | 0.0001 | 0.0150 | 0.0019 | 0.0339 | 0.0136 | 0.0662 | 0.0303 | 0.0676 | 0.0255 | 0.0968 | 0.0435 | 0.7150 | 0.8851 | 0.0033 | 0.0121 | 0.0080 | 0.0260 | 0.0256 | 0.0419 | 0.0756 | 0.1200 | 0.1388 | 0.1842 | 0.1465 | 0.1777 | 0.1385 | 0.1284 | 0.1600 | 0.1265 | 0.3036 | 0.1833 | 0.0009 | 0.0050 | 0.0135 | 0.0414 | 0.0740 | 0.1119 | 0.1069 | 0.1367 | 0.5097 | 27 | 50 | 85 | 129 | 174 | 220 | 274 | 342 | 444 | 0.0030 | 74.43 | 7.191 | 0.2347 | 74701.9 | 35300000 | 20500000000 | 14000000000000 | 0.4914 | 0.1942 | 0.0341 | 0.0005 | 0.1480 | 0.0067 | 0.2568 | 0.0741 | 0.1712 | 0.1263 | 0.1455 | 0.1772 | 0.1169 | 0.1937 | 0.0654 | 0.1449 | 0.0389 | 0.1300 | 0.0232 | 0.1465 | 0.0003 | 0.0001 | 0.0016 | 0.0005 | 0.0037 | 0.0012 | 0.0153 | 0.0094 | 0.0721 | 0.0542 | 0.1302 | 0.1070 | 0.0998 | 0.0805 | 0.1378 | 0.1181 | 0.5392 | 0.6290 | 0.0009 | 0.0021 | 0.0040 | 0.0065 | 0.0122 | 0.0178 | 0.0377 | 0.0512 | 0.1055 | 0.1206 | 0.1719 | 0.1793 | 0.1135 | 0.1149 | 0.1437 | 0.1477 | 0.4105 | 0.3599 | 0.0007 | 0.0020 | 0.0080 | 0.0239 | 0.0873 | 0.1563 | 0.1162 | 0.1382 | 0.4675 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 |