High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 1069 181 image if available 1596 20629 124.5 28.67 72.87 146.49 98 102 107 111 116 122 130 143 162 0.0438 904 0.809 207.96 60.42 1 0.3440 549 0.0093 6.72 5.134 0.4357 16321.0
2270000
339000000
54100000000
0.4382 0.2050 0.0064 0.0000 0.0064 0.0000 0.0091 0.0000 0.0246 0.0027 0.0665 0.0317 0.0938 0.0661 0.1084 0.0465 0.1321 0.0715 0.5528 0.7815 0.0051 0.0000 0.0044 0.0000 0.0066 0.0000 0.0139 0.0025 0.0285 0.0257 0.0446 0.0426 0.0599 0.0238 0.0833 0.0401 0.7538 0.8653 0.0000 0.0000 0.0037 0.0000 0.0111 0.0000 0.0406 0.0000 0.1144 0.0000 0.1476 0.0000 0.1144 0.0000 0.1255 0.0000 0.4428 0.0000 0.0016 0.0081 0.0049 0.0357 0.0535 0.1086 0.0729 0.1135 0.6013 7 9 11 12 13 15 19 61 281 0.2995 21.07 3.063 0.7088 26767.6
14200000
8950000000
6390000000000
0.3754 0.2426 0.1380 0.0048 0.3646 0.0530 0.2760 0.2133 0.1250 0.2337 0.0781 0.2422 0.0156 0.1627 0.0026 0.0590 0.0000 0.0217 0.0000 0.0096 0.0000 0.0000 0.0002 0.0000 0.0002 0.0005 0.0062 0.0050 0.0345 0.0311 0.0536 0.0493 0.0409 0.0369 0.0551 0.0516 0.8092 0.8256 0.0000 0.0000 0.0000 0.0006 0.0018 0.0030 0.0082 0.0075 0.0356 0.0413 0.0757 0.0865 0.0522 0.0543 0.0707 0.0848 0.7559 0.7221 0.0000 0.0003 0.0008 0.0058 0.0340 0.0678 0.0421 0.0646 0.7846
BT-20 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 1164 748 image if available 6717 22463 231.2 47.47 136.57 200.73 173 191 204 215 227 239 252 268 296 0.0526 1181 0.934 159.62 41.01 1 0.0582 391 0.0009 55.53 7.264 0.1600 55703.1
14000000
3650000000
990000000000
0.4604 0.1920 0.0000 0.0000 0.0000 0.0000 0.0026 0.0003 0.0127 0.0008 0.0689 0.0184 0.1261 0.0348 0.1510 0.0342 0.1834 0.0606 0.4552 0.8508 0.0000 0.0000 0.0000 0.0000 0.0016 0.0001 0.0050 0.0003 0.0314 0.0132 0.0557 0.0204 0.0683 0.0150 0.0944 0.0288 0.7437 0.9222 0.0094 0.0220 0.0122 0.0293 0.0300 0.0549 0.0880 0.1172 0.1451 0.2125 0.1751 0.1978 0.1170 0.1026 0.1517 0.1172 0.2715 0.1465 0.0006 0.0029 0.0095 0.0350 0.1008 0.1316 0.1272 0.1459 0.4464 8 10 11 13 17 50 153 289 440 0.1678 32.49 4.522 0.5734 58941.1
34500000
24900000000
22000000000000
0.4912 0.1551 0.1222 0.0039 0.3163 0.0380 0.3182 0.2866 0.1251 0.2349 0.0660 0.1696 0.0394 0.1194 0.0089 0.0653 0.0039 0.0443 0.0000 0.0380 0.0000 0.0000 0.0005 0.0001 0.0001 0.0002 0.0044 0.0063 0.0495 0.0387 0.0788 0.0683 0.0580 0.0512 0.1014 0.0836 0.7073 0.7515 0.0000 0.0003 0.0003 0.0005 0.0002 0.0016 0.0104 0.0097 0.0555 0.0675 0.1057 0.1099 0.0760 0.0890 0.1243 0.1280 0.6276 0.5934 0.0000 0.0006 0.0006 0.0083 0.0528 0.0884 0.0720 0.1141 0.6632
Hs 578T Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 1262 191 image if available 1146 5093 90.2 37.96 173.01 291.74 37 56 70 80 89 98 108 122 139 0.1056 538 0.246 326.81 58.25 3 1.2321 1412 0.0022 29.57 6.284 0.2125 9584.0
1150000
154000000
22500000000
0.3879 0.2271 0.0045 0.0000 0.0182 0.0000 0.0795 0.0040 0.0932 0.0173 0.1295 0.0840 0.1705 0.1280 0.1705 0.1333 0.1955 0.1453 0.1386 0.4880 0.0000 0.0000 0.0000 0.0000 0.0025 0.0000 0.0064 0.0032 0.0446 0.0319 0.0841 0.0554 0.0828 0.0405 0.1338 0.0692 0.6459 0.7998 0.0000 0.0106 0.0087 0.0212 0.0203 0.0159 0.0580 0.0847 0.1130 0.2328 0.1652 0.2011 0.1275 0.1164 0.1739 0.1270 0.3333 0.1905 0.0035 0.0018 0.0089 0.0319 0.0904 0.1294 0.1188 0.1489 0.4663 14 16 18 21 25 39 104 323 583 0.0764 34.57 4.571 0.5346 115023.0
109000000
127000000000
170000000000000
0.7263 0.0444 0.0738 0.0122 0.3020 0.0550 0.3087 0.1498 0.1477 0.2385 0.1208 0.2599 0.0201 0.1346 0.0134 0.0642 0.0134 0.0367 0.0000 0.0489 0.0000 0.0007 0.0028 0.0013 0.0028 0.0033 0.0264 0.0209 0.0674 0.0712 0.1035 0.0935 0.0757 0.0745 0.1070 0.1085 0.6143 0.6261 0.0016 0.0000 0.0023 0.0025 0.0047 0.0183 0.0287 0.0241 0.0636 0.0665 0.1116 0.1155 0.0853 0.0840 0.1124 0.1139 0.5899 0.5752 0.0007 0.0029 0.0066 0.0269 0.0655 0.1077 0.0852 0.1033 0.6012
BT-20 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 1011 503 image if available 8099 27715 207.4 49.29 90.32 133.45 151 164 175 187 199 212 228 248 276 0.0437 1212 1.109 152.01 45.19 2 0.0436 353 0.0011 36.08 7.089 0.1990 45423.4
10500000
2560000000
657000000000
0.4089 0.2364 0.0004 0.0000 0.0023 0.0001 0.0071 0.0004 0.0235 0.0021 0.0760 0.0188 0.1336 0.0422 0.1525 0.0391 0.1806 0.0611 0.4239 0.8362 0.0002 0.0000 0.0014 0.0000 0.0033 0.0001 0.0108 0.0006 0.0290 0.0107 0.0546 0.0216 0.0625 0.0137 0.0784 0.0235 0.7599 0.9297 0.0031 0.0101 0.0081 0.0067 0.0219 0.0236 0.0663 0.0809 0.1006 0.1720 0.1644 0.1585 0.1294 0.1282 0.1413 0.1619 0.3650 0.2580 0.0019 0.0022 0.0111 0.0259 0.0674 0.1078 0.1033 0.1236 0.5567 7 8 10 11 15 35 93 181 284 0.1964 12.37 4.050 0.6366 25966.7
10500000
5130000000
2920000000000
0.4760 0.1582 0.0839 0.0025 0.2737 0.0194 0.3606 0.1699 0.1380 0.2452 0.0745 0.2308 0.0467 0.1602 0.0182 0.0849 0.0044 0.0541 0.0000 0.0330 0.0001 0.0000 0.0004 0.0000 0.0003 0.0003 0.0065 0.0072 0.0442 0.0379 0.0776 0.0649 0.0515 0.0468 0.0806 0.0673 0.7388 0.7756 0.0000 0.0001 0.0003 0.0006 0.0004 0.0007 0.0094 0.0113 0.0554 0.0601 0.1006 0.1144 0.0720 0.0756 0.1022 0.1029 0.6597 0.6343 0.0001 0.0000 0.0006 0.0064 0.0501 0.0888 0.0621 0.0936 0.6982
BT-20 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 895 609 image if available 4883 16388 528.4 82.82 129.28 239.46 424 462 486 505 525 545 568 595 639 0.0616 1009 0.725 104.48 25.55 1 0.0555 271 0.0023 18.30 6.393 0.2729 286071.0
158000000
89700000000
51900000000000
0.4173 0.2298 0.0003 0.0000 0.0003 0.0000 0.0016 0.0000 0.0054 0.0004 0.0293 0.0147 0.0673 0.0263 0.0671 0.0165 0.1041 0.0296 0.7248 0.9125 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0023 0.0004 0.0181 0.0138 0.0331 0.0232 0.0342 0.0135 0.0512 0.0220 0.8611 0.9271 0.0036 0.0000 0.0018 0.0000 0.0309 0.0882 0.0436 0.2353 0.1291 0.2941 0.1673 0.0882 0.0800 0.1765 0.1436 0.0882 0.4000 0.0294 0.0013 0.0051 0.0131 0.0300 0.0656 0.1016 0.0863 0.1121 0.5849 7 9 10 11 13 18 55 222 459 0.2514 33.66 3.796 0.6421 74049.5
59100000
55800000000
58800000000000
0.5654 0.1070 0.1457 0.0103 0.2870 0.0432 0.3576 0.2613 0.1369 0.2469 0.0397 0.2171 0.0221 0.1235 0.0110 0.0463 0.0000 0.0267 0.0000 0.0247 0.0000 0.0002 0.0000 0.0000 0.0009 0.0004 0.0085 0.0063 0.0461 0.0469 0.0811 0.0735 0.0507 0.0480 0.0726 0.0676 0.7401 0.7571 0.0000 0.0003 0.0005 0.0000 0.0013 0.0030 0.0108 0.0120 0.0569 0.0569 0.0857 0.0867 0.0607 0.0684 0.0810 0.0878 0.7031 0.6848 0.0000 0.0000 0.0005 0.0097 0.0508 0.0832 0.0557 0.0735 0.7266
BT-20 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 355 746 image if available 5178 14618 327.7 65.14 129.72 168.91 250 272 289 304 321 339 359 383 416 0.0483 706 1.223 132.20 48.33 1 0.0624 323 0.0006 79.47 7.577 0.1347 111643.0
39500000
14500000000
5500000000000
0.4016 0.2477 0.0000 0.0000 0.0011 0.0000 0.0020 0.0000 0.0124 0.0010 0.0615 0.0141 0.1154 0.0278 0.1391 0.0377 0.1708 0.0498 0.4976 0.8695 0.0000 0.0000 0.0002 0.0000 0.0009 0.0000 0.0048 0.0006 0.0275 0.0103 0.0562 0.0177 0.0558 0.0168 0.0767 0.0242 0.7779 0.9305 0.0000 0.0057 0.0082 0.0341 0.0411 0.0625 0.0799 0.1591 0.1246 0.1932 0.1669 0.1648 0.1269 0.1193 0.1504 0.1307 0.3020 0.1307 0.0025 0.0038 0.0046 0.0302 0.0772 0.1234 0.1083 0.1318 0.5183 11 13 15 20 32 75 158 264 389 0.0486 32.17 5.262 0.4801 45355.6
21000000
11400000000
6870000000000
0.5030 0.1599 0.1206 0.0006 0.3330 0.0356 0.3146 0.2808 0.1079 0.2475 0.0769 0.1991 0.0321 0.1068 0.0115 0.0595 0.0023 0.0473 0.0011 0.0228 0.0002 0.0000 0.0002 0.0003 0.0019 0.0009 0.0117 0.0095 0.0635 0.0521 0.0928 0.0937 0.0628 0.0577 0.1074 0.0968 0.6595 0.6891 0.0007 0.0007 0.0007 0.0015 0.0029 0.0020 0.0167 0.0162 0.0625 0.0729 0.1186 0.1226 0.0783 0.0896 0.1208 0.1300 0.5988 0.5646 0.0000 0.0002 0.0037 0.0165 0.0591 0.1021 0.0779 0.1118 0.6285
SK-BR-3 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 902 486 image if available 1571 8752 79.8 18.38 25.85 63.61 59 62 66 70 75 84 92 99 106 0.0978 856 0.759 104.01 24.21 3 0.1827 287 0.0137 2.82 4.627 0.5218 6709.4
592170
54600000
5230000000
0.4037 0.2309 0.0050 0.0000 0.0099 0.0000 0.0236 0.0000 0.0459 0.0067 0.0980 0.0299 0.1613 0.0552 0.1365 0.0579 0.1675 0.0685 0.3524 0.7818 0.0033 0.0000 0.0033 0.0000 0.0117 0.0000 0.0208 0.0045 0.0400 0.0248 0.0650 0.0446 0.0550 0.0299 0.0708 0.0350 0.7300 0.8611 0.0000 0.0299 0.0000 0.0746 0.0203 0.0597 0.0330 0.1642 0.0787 0.1045 0.1320 0.1493 0.1142 0.0746 0.1345 0.1194 0.4873 0.2239 0.0000 0.0057 0.0057 0.0213 0.0355 0.0682 0.0540 0.0753 0.7344 4 5 6 6 7 8 9 12 53 0.2949 7.14 2.200 0.6924 4714.0
1480000
590000000
281000000000
0.4076 0.1755 0.0603 0.0111 0.2915 0.0379 0.4824 0.1737 0.1407 0.2517 0.0101 0.2539 0.0101 0.1403 0.0050 0.0802 0.0000 0.0379 0.0000 0.0134 0.0008 0.0035 0.0041 0.0077 0.0154 0.0153 0.0170 0.0251 0.0519 0.0537 0.0787 0.0760 0.0463 0.0530 0.0779 0.0746 0.7078 0.6911 0.0019 0.0030 0.0039 0.0020 0.0048 0.0030 0.0087 0.0071 0.0571 0.0569 0.0871 0.0944 0.0600 0.0650 0.0794 0.0792 0.6970 0.6893 0.0018 0.0090 0.0045 0.0170 0.0502 0.0806 0.0556 0.0762 0.7052
Hs 578T A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1179 272 image if available 484 417 15.1 6.24 5.44 2.42 10 11 12 12 13 15 16 18 23 0.4964 207 0.834 37.74 12.04 0 0.2397 116 0.0096 14.01 4.972 0.3037 265.5
5621.95
142364
4170000
0.3690 0.2458 0.0041 0.0000 0.0207 0.0000 0.0664 0.0000 0.1660 0.0426 0.1618 0.0727 0.1826 0.1053 0.1826 0.1328 0.1369 0.1529 0.0788 0.4937 0.0000 0.0000 0.0146 0.0000 0.0292 0.0000 0.0437 0.0325 0.0787 0.0433 0.1108 0.0584 0.1224 0.0714 0.1866 0.0952 0.4140 0.6991 0.0392 0.0000 0.0392 0.0476 0.0686 0.0635 0.0490 0.0794 0.0784 0.1429 0.1961 0.1111 0.0980 0.1111 0.1275 0.1111 0.3039 0.3333 0.0051 0.0256 0.0718 0.0821 0.1026 0.1333 0.1385 0.1179 0.3231 3 3 4 5 5 7 7 7 9 0.0300 14.00 3.917 0.2952 35.4
257.772
2032.6
17052.4
0.3900 0.1941 0.1136 0.0290 0.2652 0.0773 0.2803 0.2174 0.1667 0.2560 0.0909 0.2029 0.0530 0.1353 0.0303 0.0628 0.0000 0.0145 0.0000 0.0048 0.0032 0.0000 0.0194 0.0079 0.0809 0.0159 0.1748 0.0714 0.2201 0.1720 0.2071 0.1746 0.1909 0.2302 0.0906 0.2169 0.0129 0.1111 0.0734 0.0760 0.1751 0.2047 0.3277 0.3392 0.2260 0.2222 0.1186 0.0877 0.0395 0.0292 0.0395 0.0409 0.0000 0.0000 0.0000 0.0000 0.0072 0.0433 0.1300 0.2202 0.2238 0.1805 0.1336 0.0542 0.0072
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1212 580 image if available 1103 14618 561.7 138.16 35.88 63.16 370 419 468 517 560 608 658 706 751 0.0501 732 0.997 49.98 12.04 3 0.1024 113 0.0028 12.27 6.069 0.2960 334620.0
209000000
136000000000
91500000000000
0.3419 0.2943 0.0000 0.0000 0.0000 0.0000 0.0057 0.0000 0.0170 0.0039 0.0679 0.0309 0.1434 0.0588 0.0830 0.0366 0.1264 0.0723 0.5566 0.7975 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0049 0.0019 0.0317 0.0272 0.0537 0.0497 0.0305 0.0244 0.0464 0.0384 0.8327 0.8585 0.0035 0.0667 0.0035 0.1000 0.0069 0.0667 0.0277 0.0667 0.0415 0.1667 0.1073 0.1667 0.0415 0.1000 0.0484 0.1333 0.7197 0.1333 0.0000 0.0000 0.0037 0.0147 0.0367 0.0606 0.0495 0.0495 0.7853 5 6 8 9 10 12 16 40 115 0.1429 1.10 2.444 0.5930 5276.5
1200000
317000000
92500000000
0.4895 0.1637 0.0684 0.0063 0.2928 0.0125 0.3403 0.0859 0.1521 0.2560 0.0665 0.3196 0.0418 0.1674 0.0209 0.0859 0.0114 0.0358 0.0057 0.0304 0.0003 0.0008 0.0006 0.0013 0.0015 0.0043 0.0150 0.0179 0.0479 0.0415 0.0814 0.0672 0.0568 0.0573 0.0912 0.0851 0.7054 0.7246 0.0000 0.0000 0.0000 0.0008 0.0043 0.0011 0.0149 0.0164 0.0532 0.0611 0.0987 0.1019 0.0664 0.0710 0.1015 0.1111 0.6610 0.6366 0.0000 0.0003 0.0036 0.0098 0.0577 0.0925 0.0584 0.1013 0.6764
MCF 10A Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 706 476 image if available 728 1022 96.1 32.97 217.29 252.33 64 70 76 81 87 93 104 119 143 0.2652 271 0.410 145.45 41.40 1 0.7843 571 0.0039 22.73 5.781 0.2516 10321.1
1250000
169000000
25300000000
0.4351 0.2119 0.0000 0.0000 0.0173 0.0066 0.0202 0.0099 0.0980 0.0066 0.2161 0.0724 0.2017 0.0938 0.2017 0.0674 0.1441 0.1628 0.1009 0.5806 0.0000 0.0000 0.0000 0.0000 0.0020 0.0000 0.0296 0.0029 0.1006 0.0471 0.1381 0.0799 0.1282 0.0428 0.1440 0.1084 0.4576 0.7190 0.0000 0.0215 0.0000 0.0000 0.0375 0.0000 0.0625 0.0753 0.1438 0.1183 0.1563 0.1720 0.1063 0.2151 0.1438 0.1398 0.3500 0.2581 0.0037 0.0000 0.0112 0.0669 0.1227 0.1450 0.0558 0.1004 0.4944 18 22 28 45 88 168 297 431 602 0.0497 49.53 4.975 0.4355 110822.0
73200000
55400000000
45800000000000
0.5813 0.0827 0.1029 0.0000 0.2500 0.0581 0.3971 0.1806 0.1324 0.2581 0.0735 0.2387 0.0147 0.1355 0.0294 0.0774 0.0000 0.0387 0.0000 0.0129 0.0000 0.0000 0.0050 0.0022 0.0074 0.0022 0.0074 0.0285 0.0695 0.0724 0.1390 0.1162 0.0893 0.0943 0.1216 0.1250 0.5608 0.5592 0.0000 0.0000 0.0000 0.0033 0.0090 0.0000 0.0090 0.0233 0.0746 0.0731 0.1731 0.1728 0.0836 0.1163 0.1313 0.1262 0.5194 0.4851 0.0000 0.0000 0.0028 0.0110 0.0579 0.1818 0.0661 0.1350 0.5455
Hs 578T Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 862 60 image if available 536 8372 94.9 38.62 150.81 294.15 38 55 70 85 97 109 121 135 146 0.0688 576 0.456 105.65 21.93 2 0.7705 413 0.0025 45.30 6.078 0.1747 10500.4
1270000
163000000
21700000000
0.3490 0.2577 0.0000 0.0032 0.0057 0.0000 0.0345 0.0000 0.1149 0.0097 0.1782 0.0968 0.1782 0.1452 0.1322 0.1161 0.1379 0.1613 0.2184 0.4677 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0137 0.0024 0.0521 0.0471 0.0493 0.0659 0.0548 0.0329 0.0740 0.0776 0.7562 0.7741 0.0000 0.0000 0.0052 0.0000 0.0052 0.0087 0.0209 0.0435 0.0995 0.1130 0.0785 0.1130 0.1099 0.1217 0.1152 0.1739 0.5654 0.4261 0.0000 0.0000 0.0035 0.0142 0.0745 0.0816 0.0780 0.0957 0.6525 15 18 20 22 25 32 64 197 482 0.1543 30.36 3.816 0.6306 109258.0
124000000
171000000000
266000000000000
0.6017 0.0867 0.1678 0.0032 0.3557 0.0852 0.2550 0.2981 0.1040 0.2618 0.0570 0.1467 0.0336 0.1073 0.0201 0.0442 0.0067 0.0331 0.0000 0.0205 0.0010 0.0004 0.0025 0.0018 0.0029 0.0031 0.0152 0.0161 0.0678 0.0629 0.1130 0.0915 0.0683 0.0683 0.1170 0.1071 0.6123 0.6488 0.0006 0.0006 0.0012 0.0006 0.0069 0.0056 0.0242 0.0311 0.0806 0.0840 0.1163 0.1319 0.0996 0.0989 0.1232 0.1319 0.5475 0.5152 0.0011 0.0021 0.0037 0.0144 0.0880 0.1077 0.0859 0.1189 0.5781
BT-20 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 312 733 image if available 7233 20217 523.9 88.32 192.73 354.08 412 444 470 496 519 544 571 604 641 0.0504 1018 1.154 114.98 42.58 1 0.0408 295 0.0018 19.88 6.575 0.2459 282245.0
156000000
88600000000
51500000000000
0.4172 0.2311 0.0002 0.0000 0.0000 0.0000 0.0022 0.0003 0.0114 0.0004 0.0461 0.0113 0.0920 0.0228 0.1143 0.0150 0.1514 0.0291 0.5824 0.9210 0.0000 0.0000 0.0000 0.0000 0.0005 0.0000 0.0046 0.0001 0.0219 0.0096 0.0442 0.0195 0.0517 0.0096 0.0720 0.0186 0.8052 0.9427 0.0032 0.0494 0.0085 0.0247 0.0481 0.0617 0.1068 0.2099 0.1474 0.1481 0.1699 0.1728 0.1453 0.1605 0.1271 0.1111 0.2436 0.0617 0.0014 0.0026 0.0072 0.0203 0.0629 0.1090 0.0973 0.1296 0.5697 10 12 14 16 19 32 110 339 644 0.1456 63.21 4.433 0.6015 162507.0
200000000
303000000000
525000000000000
0.5064 0.1533 0.1318 0.0049 0.3100 0.0323 0.3324 0.2391 0.1234 0.2742 0.0561 0.2167 0.0351 0.1220 0.0042 0.0617 0.0056 0.0358 0.0014 0.0133 0.0000 0.0000 0.0000 0.0002 0.0005 0.0003 0.0070 0.0065 0.0491 0.0410 0.0772 0.0740 0.0498 0.0478 0.0813 0.0702 0.7351 0.7600 0.0000 0.0000 0.0002 0.0002 0.0004 0.0017 0.0119 0.0114 0.0544 0.0623 0.0908 0.0925 0.0634 0.0717 0.0934 0.1071 0.6854 0.6531 0.0000 0.0002 0.0008 0.0084 0.0511 0.0851 0.0532 0.0876 0.7136
BT-20 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 179 861 image if available 6894 24993 432.7 77.04 123.09 229.52 337 363 385 406 427 448 470 497 536 0.0541 1352 1.247 106.10 42.20 2 0.0392 270 0.0024 14.62 6.292 0.2830 193164.0
88900000
42200000000
20600000000000
0.4573 0.1908 0.0002 0.0000 0.0008 0.0000 0.0034 0.0000 0.0121 0.0006 0.0472 0.0149 0.0960 0.0253 0.1212 0.0267 0.1545 0.0354 0.5647 0.8972 0.0002 0.0000 0.0003 0.0000 0.0017 0.0000 0.0065 0.0001 0.0253 0.0121 0.0467 0.0177 0.0549 0.0126 0.0783 0.0167 0.7863 0.9408 0.0053 0.0000 0.0160 0.0701 0.0299 0.0764 0.0812 0.1783 0.1335 0.1720 0.1656 0.1783 0.1186 0.1274 0.1346 0.0955 0.3152 0.1019 0.0009 0.0037 0.0079 0.0244 0.0711 0.1200 0.1053 0.1236 0.5430 8 10 12 13 16 23 63 188 422 0.2078 29.75 3.972 0.6370 67827.8
55500000
55600000000
63900000000000
0.4521 0.1694 0.1333 0.0042 0.3651 0.0371 0.3035 0.2123 0.1120 0.2751 0.0504 0.2537 0.0202 0.1124 0.0090 0.0570 0.0045 0.0314 0.0022 0.0167 0.0002 0.0000 0.0002 0.0003 0.0014 0.0008 0.0135 0.0108 0.0527 0.0490 0.0825 0.0789 0.0578 0.0500 0.0808 0.0738 0.7110 0.7365 0.0002 0.0004 0.0009 0.0010 0.0018 0.0029 0.0147 0.0130 0.0575 0.0617 0.0963 0.1072 0.0686 0.0675 0.0945 0.1032 0.6655 0.6432 0.0007 0.0005 0.0013 0.0119 0.0549 0.0931 0.0549 0.0860 0.6968
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1130 460 image if available 653 578 83.3 9.22 65.56 101.38 71 74 78 80 83 86 89 92 95 0.3910 226 0.478 77.79 11.31 1 0.3155 206 0.1159 0.55 2.394 0.7678 7017.7
598559
51600000
4510000000
0.4222 0.2132 0.0000 0.0000 0.0000 0.0000 0.0032 0.0000 0.0065 0.0015 0.0455 0.0352 0.0698 0.0674 0.0779 0.0260 0.1347 0.0475 0.6623 0.8224 0.0000 0.0000 0.0000 0.0000 0.0031 0.0000 0.0047 0.0015 0.0376 0.0352 0.0610 0.0674 0.0297 0.0260 0.0563 0.0475 0.8075 0.8224 0.1304 0.0000 0.3478 0.0000 0.2174 0.0000 0.1304 0.0000 0.0870 0.0000 0.0435 0.0000 0.0435 0.0000 0.0000 0.0000 0.0000 0.0000 0.0030 0.0151 0.0211 0.0452 0.0994 0.0964 0.1325 0.1687 0.4187 7 10 13 18 24 35 52 90 200 0.0809 31.27 3.431 0.5091 14559.2
5410000
2520000000
1320000000000
0.5610 0.0846 0.2727 0.0094 0.5000 0.0377 0.2273 0.4151 0.0000 0.3396 0.0000 0.1038 0.0000 0.0849 0.0000 0.0094 0.0000 0.0000 0.0000 0.0000 0.0000 0.0046 0.0405 0.0091 0.0173 0.0274 0.0347 0.0365 0.2023 0.1507 0.3410 0.3196 0.1676 0.1553 0.1850 0.1918 0.0116 0.1050 0.0155 0.0177 0.0233 0.0265 0.0698 0.0885 0.0853 0.0619 0.2636 0.3894 0.3488 0.3009 0.1860 0.1150 0.0078 0.0000 0.0000 0.0000 0.0134 0.0201 0.0336 0.0336 0.2282 0.3758 0.2013 0.0940 0.0000