High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 140 | | 4015 | 11442 | 298.5 | 93.89 | 283.49 | 327.91 | 188 | 224 | 248 | 270 | 290 | 313 | 337 | 371 | 423 | 0.0718 | 821 | 0.641 | 110.89 | 16.16 | 3 | 0.0590 | 237 | 0.0005 | 119.77 | 7.721 | 0.1137 | 97912.3 | 34900000 | 13400000000 | 5490000000000 | 0.4228 | 0.1994 | 0.0000 | 0.0000 | 0.0005 | 0.0003 | 0.0078 | 0.0000 | 0.0352 | 0.0049 | 0.0906 | 0.0391 | 0.1684 | 0.0564 | 0.1361 | 0.0524 | 0.1522 | 0.0795 | 0.4092 | 0.7675 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0135 | 0.0016 | 0.0347 | 0.0237 | 0.0663 | 0.0307 | 0.0579 | 0.0234 | 0.0710 | 0.0373 | 0.7547 | 0.8833 | 0.0011 | 0.0093 | 0.0032 | 0.0023 | 0.0086 | 0.0163 | 0.0452 | 0.0629 | 0.0893 | 0.0979 | 0.1453 | 0.1375 | 0.0969 | 0.1235 | 0.1163 | 0.1142 | 0.4941 | 0.4359 | 0.0005 | 0.0005 | 0.0032 | 0.0244 | 0.0684 | 0.1087 | 0.0976 | 0.1124 | 0.5843 | 18 | 23 | 31 | 69 | 150 | 246 | 370 | 532 | 762 | 0.0260 | 64.88 | 6.232 | 0.4074 | 187886.0 | 166000000 | 173000000000 | 201000000000000 | 0.6183 | 0.1150 | 0.0315 | 0.0018 | 0.0954 | 0.0093 | 0.2028 | 0.0466 | 0.1778 | 0.0888 | 0.1759 | 0.1607 | 0.1389 | 0.1793 | 0.0880 | 0.1474 | 0.0528 | 0.1482 | 0.0370 | 0.2179 | 0.0008 | 0.0000 | 0.0015 | 0.0004 | 0.0054 | 0.0022 | 0.0149 | 0.0104 | 0.0492 | 0.0440 | 0.0677 | 0.0593 | 0.0620 | 0.0557 | 0.0989 | 0.0825 | 0.6996 | 0.7454 | 0.0014 | 0.0000 | 0.0038 | 0.0019 | 0.0049 | 0.0074 | 0.0181 | 0.0211 | 0.0585 | 0.0692 | 0.0937 | 0.0977 | 0.0766 | 0.0922 | 0.1110 | 0.1151 | 0.6320 | 0.5954 | 0.0005 | 0.0026 | 0.0062 | 0.0133 | 0.0554 | 0.0778 | 0.0700 | 0.1011 | 0.6730 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 216 | 528 | | 5345 | 6687 | 126.2 | 29.45 | 246.37 | 196.30 | 92 | 102 | 109 | 116 | 122 | 129 | 137 | 148 | 166 | 0.1069 | 715 | 0.821 | 98.35 | 24.08 | 1 | 0.0462 | 247 | 0.0025 | 20.42 | 6.327 | 0.2607 | 16786.6 | 2360000 | 350000000 | 54900000000 | 0.4217 | 0.2280 | 0.0006 | 0.0000 | 0.0020 | 0.0002 | 0.0049 | 0.0002 | 0.0260 | 0.0037 | 0.0795 | 0.0242 | 0.1393 | 0.0480 | 0.1549 | 0.0494 | 0.1980 | 0.0730 | 0.3948 | 0.8015 | 0.0002 | 0.0000 | 0.0014 | 0.0002 | 0.0025 | 0.0000 | 0.0114 | 0.0013 | 0.0377 | 0.0144 | 0.0616 | 0.0276 | 0.0705 | 0.0203 | 0.1045 | 0.0325 | 0.7102 | 0.9036 | 0.0065 | 0.0029 | 0.0043 | 0.0324 | 0.0293 | 0.0412 | 0.0759 | 0.1265 | 0.1605 | 0.1765 | 0.1811 | 0.1882 | 0.1215 | 0.1500 | 0.1443 | 0.1412 | 0.2766 | 0.1412 | 0.0037 | 0.0058 | 0.0146 | 0.0379 | 0.0853 | 0.1328 | 0.1087 | 0.1424 | 0.4688 | 29 | 68 | 108 | 156 | 206 | 258 | 323 | 400 | 511 | 0.0020 | 102.03 | 7.263 | 0.2296 | 99223.3 | 51700000 | 32100000000 | 22600000000000 | 0.4373 | 0.2354 | 0.0192 | 0.0026 | 0.0936 | 0.0096 | 0.1554 | 0.0379 | 0.1930 | 0.0889 | 0.1696 | 0.1612 | 0.1637 | 0.1886 | 0.0952 | 0.1468 | 0.0693 | 0.1476 | 0.0409 | 0.2169 | 0.0003 | 0.0010 | 0.0017 | 0.0010 | 0.0063 | 0.0027 | 0.0199 | 0.0129 | 0.0515 | 0.0493 | 0.1085 | 0.0818 | 0.0863 | 0.0592 | 0.1102 | 0.0896 | 0.6153 | 0.7027 | 0.0000 | 0.0000 | 0.0026 | 0.0055 | 0.0110 | 0.0197 | 0.0408 | 0.0466 | 0.0891 | 0.1102 | 0.1414 | 0.1694 | 0.1137 | 0.1190 | 0.1378 | 0.1464 | 0.4636 | 0.3832 | 0.0007 | 0.0028 | 0.0067 | 0.0245 | 0.0823 | 0.1199 | 0.0986 | 0.1341 | 0.5303 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 786 | 723 | | 4403 | 10505 | 156.8 | 37.21 | 158.32 | 156.07 | 111 | 125 | 136 | 145 | 154 | 163 | 173 | 187 | 207 | 0.0730 | 767 | 1.082 | 105.15 | 39.01 | 1 | 0.0620 | 273 | 0.0017 | 27.23 | 6.665 | 0.2280 | 25980.4 | 4530000 | 831000000 | 159000000000 | 0.4286 | 0.2358 | 0.0007 | 0.0000 | 0.0045 | 0.0003 | 0.0138 | 0.0018 | 0.0302 | 0.0040 | 0.0832 | 0.0260 | 0.1542 | 0.0510 | 0.1486 | 0.0545 | 0.1725 | 0.0808 | 0.3923 | 0.7817 | 0.0000 | 0.0000 | 0.0009 | 0.0002 | 0.0009 | 0.0002 | 0.0068 | 0.0009 | 0.0392 | 0.0176 | 0.0717 | 0.0309 | 0.0697 | 0.0248 | 0.0958 | 0.0405 | 0.7151 | 0.8849 | 0.0024 | 0.0182 | 0.0155 | 0.0146 | 0.0274 | 0.0474 | 0.0764 | 0.1314 | 0.1372 | 0.1788 | 0.2076 | 0.2336 | 0.1313 | 0.0985 | 0.1396 | 0.1314 | 0.2625 | 0.1460 | 0.0024 | 0.0015 | 0.0068 | 0.0336 | 0.0973 | 0.1357 | 0.1051 | 0.1367 | 0.4810 | 15 | 27 | 45 | 75 | 110 | 150 | 199 | 265 | 380 | 0.0051 | 65.67 | 6.760 | 0.3104 | 49420.1 | 21200000 | 11000000000 | 6460000000000 | 0.5076 | 0.1389 | 0.0172 | 0.0010 | 0.0968 | 0.0078 | 0.2177 | 0.0413 | 0.1765 | 0.0889 | 0.1820 | 0.1633 | 0.1360 | 0.1965 | 0.0859 | 0.1508 | 0.0522 | 0.1403 | 0.0357 | 0.2100 | 0.0006 | 0.0000 | 0.0015 | 0.0009 | 0.0038 | 0.0042 | 0.0125 | 0.0116 | 0.0563 | 0.0446 | 0.0987 | 0.0767 | 0.0747 | 0.0616 | 0.1081 | 0.0892 | 0.6439 | 0.7113 | 0.0009 | 0.0015 | 0.0030 | 0.0036 | 0.0093 | 0.0109 | 0.0246 | 0.0318 | 0.0818 | 0.0982 | 0.1325 | 0.1383 | 0.0971 | 0.0985 | 0.1250 | 0.1438 | 0.5259 | 0.4734 | 0.0002 | 0.0017 | 0.0057 | 0.0214 | 0.0664 | 0.1176 | 0.0927 | 0.1161 | 0.5782 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 541 | 522 | | 7538 | 10729 | 182.1 | 53.16 | 151.55 | 105.15 | 123 | 138 | 150 | 162 | 173 | 185 | 200 | 220 | 253 | 0.0842 | 903 | 1.033 | 124.56 | 28.32 | 1 | 0.0358 | 270 | 0.0011 | 47.33 | 7.166 | 0.1859 | 35971.8 | 7740000 | 1820000000 | 464000000000 | 0.4607 | 0.1986 | 0.0008 | 0.0002 | 0.0033 | 0.0003 | 0.0110 | 0.0014 | 0.0358 | 0.0038 | 0.1099 | 0.0259 | 0.1983 | 0.0649 | 0.1693 | 0.0640 | 0.1888 | 0.0978 | 0.2827 | 0.7419 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0075 | 0.0010 | 0.0464 | 0.0143 | 0.0907 | 0.0329 | 0.0762 | 0.0285 | 0.1180 | 0.0474 | 0.6588 | 0.8759 | 0.0038 | 0.0055 | 0.0070 | 0.0083 | 0.0203 | 0.0290 | 0.0725 | 0.0981 | 0.1462 | 0.1630 | 0.1697 | 0.2003 | 0.1132 | 0.1077 | 0.1373 | 0.1436 | 0.3299 | 0.2445 | 0.0003 | 0.0050 | 0.0050 | 0.0400 | 0.1026 | 0.1488 | 0.1079 | 0.1417 | 0.4487 | 38 | 59 | 80 | 102 | 128 | 157 | 190 | 236 | 297 | 0.0020 | 46.88 | 6.872 | 0.2760 | 34024.8 | 9800000 | 3360000000 | 1320000000000 | 0.5574 | 0.1310 | 0.0165 | 0.0000 | 0.1056 | 0.0050 | 0.2130 | 0.0382 | 0.1703 | 0.0893 | 0.1387 | 0.1551 | 0.1488 | 0.2086 | 0.0826 | 0.1535 | 0.0716 | 0.1259 | 0.0528 | 0.2244 | 0.0005 | 0.0000 | 0.0002 | 0.0006 | 0.0020 | 0.0016 | 0.0138 | 0.0112 | 0.0620 | 0.0424 | 0.1227 | 0.0865 | 0.0888 | 0.0730 | 0.1299 | 0.1037 | 0.5802 | 0.6811 | 0.0006 | 0.0004 | 0.0029 | 0.0049 | 0.0119 | 0.0162 | 0.0365 | 0.0503 | 0.1192 | 0.1521 | 0.1812 | 0.1923 | 0.1190 | 0.1367 | 0.1520 | 0.1559 | 0.3768 | 0.2911 | 0.0002 | 0.0009 | 0.0049 | 0.0238 | 0.0980 | 0.1462 | 0.1128 | 0.1557 | 0.4576 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 825 | 684 | | 7651 | 20186 | 434.9 | 80.92 | 100.21 | 97.16 | 337 | 366 | 390 | 409 | 429 | 448 | 471 | 501 | 545 | 0.0502 | 1013 | 1.138 | 102.84 | 33.06 | 1 | 0.0322 | 246 | 0.0009 | 43.02 | 7.234 | 0.1788 | 195716.0 | 91000000 | 43700000000 | 21700000000000 | 0.4528 | 0.2044 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0003 | 0.0109 | 0.0004 | 0.0464 | 0.0156 | 0.1085 | 0.0248 | 0.1193 | 0.0267 | 0.1502 | 0.0416 | 0.5632 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0047 | 0.0004 | 0.0241 | 0.0132 | 0.0533 | 0.0176 | 0.0554 | 0.0141 | 0.0757 | 0.0217 | 0.7862 | 0.9330 | 0.0026 | 0.0221 | 0.0123 | 0.0608 | 0.0202 | 0.0663 | 0.0792 | 0.1381 | 0.1206 | 0.1547 | 0.1637 | 0.1381 | 0.1021 | 0.1105 | 0.1144 | 0.1050 | 0.3847 | 0.2044 | 0.0011 | 0.0050 | 0.0089 | 0.0319 | 0.0727 | 0.1248 | 0.1040 | 0.1262 | 0.5255 | 9 | 12 | 22 | 46 | 73 | 101 | 133 | 177 | 238 | 0.0261 | 11.79 | 5.435 | 0.4724 | 19482.1 | 5010000 | 1530000000 | 533000000000 | 0.4602 | 0.1900 | 0.0169 | 0.0009 | 0.0928 | 0.0052 | 0.1893 | 0.0424 | 0.1626 | 0.0894 | 0.1630 | 0.1492 | 0.1587 | 0.1861 | 0.0954 | 0.1402 | 0.0745 | 0.1464 | 0.0468 | 0.2402 | 0.0006 | 0.0001 | 0.0007 | 0.0006 | 0.0017 | 0.0015 | 0.0093 | 0.0072 | 0.0425 | 0.0340 | 0.0820 | 0.0612 | 0.0679 | 0.0521 | 0.0976 | 0.0811 | 0.6977 | 0.7621 | 0.0009 | 0.0007 | 0.0013 | 0.0023 | 0.0028 | 0.0042 | 0.0180 | 0.0214 | 0.0688 | 0.0820 | 0.1143 | 0.1324 | 0.0930 | 0.0958 | 0.1199 | 0.1291 | 0.5810 | 0.5321 | 0.0007 | 0.0011 | 0.0034 | 0.0138 | 0.0527 | 0.0963 | 0.0820 | 0.1141 | 0.6359 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 593 | 809 | | 9054 | 36760 | 386.6 | 78.38 | 181.80 | 168.48 | 283 | 319 | 345 | 368 | 389 | 408 | 428 | 453 | 485 | 0.0343 | 1261 | 1.172 | 117.32 | 46.07 | 2 | 0.0357 | 323 | 0.0013 | 28.99 | 6.930 | 0.2068 | 155613.0 | 64900000 | 28000000000 | 12400000000000 | 0.4514 | 0.1993 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0031 | 0.0000 | 0.0122 | 0.0006 | 0.0609 | 0.0126 | 0.1366 | 0.0323 | 0.1416 | 0.0335 | 0.1674 | 0.0533 | 0.4776 | 0.8677 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0025 | 0.0000 | 0.0256 | 0.0110 | 0.0577 | 0.0252 | 0.0556 | 0.0184 | 0.0717 | 0.0277 | 0.7858 | 0.9178 | 0.0076 | 0.0205 | 0.0124 | 0.1231 | 0.0275 | 0.0923 | 0.0927 | 0.1282 | 0.1683 | 0.1692 | 0.1999 | 0.1538 | 0.1484 | 0.0974 | 0.1374 | 0.1077 | 0.2060 | 0.1077 | 0.0006 | 0.0009 | 0.0039 | 0.0214 | 0.0744 | 0.1309 | 0.1084 | 0.1493 | 0.5102 | 20 | 40 | 70 | 101 | 134 | 175 | 226 | 293 | 410 | 0.0090 | 24.30 | 6.122 | 0.3733 | 61436.3 | 29700000 | 18600000000 | 14600000000000 | 0.4309 | 0.1918 | 0.0224 | 0.0007 | 0.1034 | 0.0058 | 0.2259 | 0.0487 | 0.1796 | 0.0900 | 0.1556 | 0.1611 | 0.1385 | 0.1955 | 0.0838 | 0.1496 | 0.0540 | 0.1427 | 0.0368 | 0.2058 | 0.0002 | 0.0003 | 0.0014 | 0.0006 | 0.0040 | 0.0027 | 0.0165 | 0.0104 | 0.0562 | 0.0443 | 0.1108 | 0.0905 | 0.0855 | 0.0719 | 0.1171 | 0.1021 | 0.6083 | 0.6773 | 0.0012 | 0.0016 | 0.0027 | 0.0043 | 0.0087 | 0.0124 | 0.0274 | 0.0393 | 0.0838 | 0.0961 | 0.1402 | 0.1499 | 0.1102 | 0.1133 | 0.1381 | 0.1378 | 0.4877 | 0.4453 | 0.0006 | 0.0015 | 0.0052 | 0.0174 | 0.0731 | 0.1259 | 0.1003 | 0.1286 | 0.5475 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 266 | 832 | | 5052 | 10241 | 147.7 | 42.12 | 164.11 | 146.78 | 101 | 114 | 123 | 132 | 141 | 151 | 163 | 178 | 201 | 0.0842 | 862 | 1.052 | 93.96 | 28.02 | 1 | 0.0449 | 227 | 0.0015 | 34.75 | 6.782 | 0.2136 | 23601.0 | 4100000 | 775000000 | 160000000000 | 0.4351 | 0.2145 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0119 | 0.0004 | 0.0418 | 0.0025 | 0.1162 | 0.0275 | 0.1757 | 0.0555 | 0.1934 | 0.0737 | 0.1916 | 0.1095 | 0.2680 | 0.7309 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0152 | 0.0008 | 0.0452 | 0.0174 | 0.0714 | 0.0304 | 0.0903 | 0.0289 | 0.1092 | 0.0521 | 0.6665 | 0.8702 | 0.0029 | 0.0073 | 0.0164 | 0.0171 | 0.0299 | 0.0465 | 0.0598 | 0.1345 | 0.1583 | 0.1736 | 0.1631 | 0.1760 | 0.1361 | 0.1100 | 0.1544 | 0.1271 | 0.2790 | 0.2078 | 0.0023 | 0.0041 | 0.0120 | 0.0322 | 0.0989 | 0.1427 | 0.1141 | 0.1542 | 0.4395 | 13 | 30 | 59 | 89 | 123 | 168 | 218 | 280 | 374 | 0.0051 | 65.13 | 6.912 | 0.2905 | 48476.3 | 18800000 | 8740000000 | 4630000000000 | 0.4979 | 0.1489 | 0.0225 | 0.0023 | 0.1359 | 0.0100 | 0.2239 | 0.0492 | 0.1838 | 0.0904 | 0.1746 | 0.1755 | 0.1352 | 0.2178 | 0.0803 | 0.1586 | 0.0331 | 0.1509 | 0.0106 | 0.1453 | 0.0000 | 0.0002 | 0.0014 | 0.0012 | 0.0045 | 0.0043 | 0.0163 | 0.0104 | 0.0593 | 0.0502 | 0.0964 | 0.0849 | 0.0821 | 0.0672 | 0.1055 | 0.0971 | 0.6345 | 0.6846 | 0.0014 | 0.0028 | 0.0029 | 0.0077 | 0.0063 | 0.0120 | 0.0284 | 0.0359 | 0.0831 | 0.0921 | 0.1287 | 0.1354 | 0.1006 | 0.1051 | 0.1284 | 0.1343 | 0.5201 | 0.4747 | 0.0002 | 0.0029 | 0.0059 | 0.0176 | 0.0699 | 0.1148 | 0.0813 | 0.1176 | 0.5899 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 619 | 861 | | 3334 | 9894 | 194.2 | 63.45 | 194.29 | 151.46 | 124 | 139 | 154 | 168 | 183 | 201 | 221 | 246 | 280 | 0.0730 | 722 | 0.462 | 118.15 | 25.02 | 1 | 0.1041 | 347 | 0.0006 | 128.05 | 7.588 | 0.1119 | 41739.0 | 9880000 | 2560000000 | 721000000000 | 0.4295 | 0.2204 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0015 | 0.0524 | 0.0063 | 0.1427 | 0.0431 | 0.1999 | 0.0822 | 0.1730 | 0.0778 | 0.1675 | 0.1202 | 0.2426 | 0.6690 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0039 | 0.0000 | 0.0144 | 0.0039 | 0.0471 | 0.0228 | 0.0781 | 0.0449 | 0.0663 | 0.0308 | 0.0938 | 0.0555 | 0.6958 | 0.8421 | 0.0012 | 0.0050 | 0.0024 | 0.0050 | 0.0060 | 0.0298 | 0.0393 | 0.0720 | 0.1262 | 0.1687 | 0.1738 | 0.1687 | 0.0952 | 0.1092 | 0.1333 | 0.1365 | 0.4226 | 0.3052 | 0.0014 | 0.0014 | 0.0082 | 0.0199 | 0.0694 | 0.1223 | 0.0804 | 0.1154 | 0.5817 | 32 | 63 | 95 | 127 | 160 | 199 | 246 | 304 | 396 | 0.0037 | 29.49 | 6.429 | 0.2958 | 60686.3 | 25300000 | 12900000000 | 7630000000000 | 0.5774 | 0.1179 | 0.0296 | 0.0011 | 0.1266 | 0.0053 | 0.2181 | 0.0429 | 0.1967 | 0.0911 | 0.1622 | 0.1735 | 0.1184 | 0.2026 | 0.0789 | 0.1626 | 0.0488 | 0.1505 | 0.0208 | 0.1703 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0034 | 0.0016 | 0.0232 | 0.0134 | 0.0774 | 0.0517 | 0.1295 | 0.0963 | 0.1053 | 0.0884 | 0.1348 | 0.1199 | 0.5252 | 0.6283 | 0.0006 | 0.0032 | 0.0043 | 0.0073 | 0.0115 | 0.0218 | 0.0449 | 0.0638 | 0.1172 | 0.1344 | 0.1596 | 0.1707 | 0.1206 | 0.1287 | 0.1522 | 0.1493 | 0.3890 | 0.3208 | 0.0015 | 0.0027 | 0.0089 | 0.0332 | 0.0904 | 0.1524 | 0.1096 | 0.1362 | 0.4652 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 518 | 503 | | 15648 | 56021 | 320.9 | 59.50 | 142.33 | 181.99 | 244 | 279 | 299 | 315 | 329 | 341 | 354 | 368 | 389 | 0.0239 | 1341 | 0.987 | 126.85 | 36.01 | 1 | 0.0202 | 316 | 0.0015 | 21.65 | 6.855 | 0.2488 | 106538.0 | 36300000 | 12600000000 | 4480000000000 | 0.4413 | 0.2040 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0079 | 0.0003 | 0.0295 | 0.0078 | 0.0562 | 0.0157 | 0.0615 | 0.0104 | 0.0915 | 0.0162 | 0.7503 | 0.9496 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0109 | 0.0075 | 0.0242 | 0.0143 | 0.0210 | 0.0081 | 0.0316 | 0.0119 | 0.9098 | 0.9580 | 0.0090 | 0.0536 | 0.0157 | 0.0179 | 0.0336 | 0.1429 | 0.0745 | 0.2143 | 0.1272 | 0.1429 | 0.1557 | 0.1607 | 0.1429 | 0.1071 | 0.1597 | 0.0357 | 0.2818 | 0.1250 | 0.0008 | 0.0025 | 0.0050 | 0.0158 | 0.0410 | 0.0684 | 0.0815 | 0.0977 | 0.6873 | 8 | 10 | 12 | 18 | 51 | 108 | 178 | 269 | 424 | 0.1076 | 16.66 | 4.969 | 0.5393 | 53375.8 | 26600000 | 15300000000 | 9680000000000 | 0.3694 | 0.2725 | 0.0166 | 0.0013 | 0.1012 | 0.0060 | 0.2168 | 0.0361 | 0.1910 | 0.0912 | 0.1770 | 0.1724 | 0.1403 | 0.2115 | 0.0824 | 0.1547 | 0.0457 | 0.1475 | 0.0291 | 0.1792 | 0.0006 | 0.0002 | 0.0006 | 0.0006 | 0.0027 | 0.0015 | 0.0085 | 0.0065 | 0.0354 | 0.0299 | 0.0682 | 0.0565 | 0.0555 | 0.0459 | 0.0719 | 0.0641 | 0.7567 | 0.7947 | 0.0005 | 0.0005 | 0.0022 | 0.0022 | 0.0040 | 0.0048 | 0.0126 | 0.0154 | 0.0463 | 0.0551 | 0.0837 | 0.0934 | 0.0695 | 0.0743 | 0.0862 | 0.0911 | 0.6950 | 0.6633 | 0.0005 | 0.0017 | 0.0041 | 0.0114 | 0.0416 | 0.0737 | 0.0613 | 0.0797 | 0.7260 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 307 | 284 | | 4454 | 15705 | 541.8 | 126.10 | 114.66 | 191.51 | 395 | 434 | 463 | 491 | 521 | 551 | 591 | 651 | 728 | 0.0554 | 870 | 1.060 | 102.88 | 27.59 | 2 | 0.0534 | 238 | 0.0008 | 82.33 | 7.369 | 0.1665 | 309466.0 | 186000000 | 118000000000 | 78000000000000 | 0.4066 | 0.2345 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0005 | 0.0157 | 0.0027 | 0.0737 | 0.0261 | 0.1377 | 0.0438 | 0.1448 | 0.0443 | 0.1534 | 0.0597 | 0.4611 | 0.8229 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0056 | 0.0002 | 0.0407 | 0.0161 | 0.0709 | 0.0258 | 0.0709 | 0.0192 | 0.0895 | 0.0269 | 0.7210 | 0.9117 | 0.0022 | 0.0032 | 0.0000 | 0.0160 | 0.0078 | 0.0415 | 0.0526 | 0.0927 | 0.0973 | 0.1629 | 0.1353 | 0.1502 | 0.0839 | 0.1086 | 0.1074 | 0.1438 | 0.5134 | 0.2812 | 0.0000 | 0.0031 | 0.0062 | 0.0333 | 0.0868 | 0.1149 | 0.1004 | 0.1108 | 0.5445 | 5 | 7 | 8 | 10 | 11 | 17 | 98 | 220 | 400 | 0.1818 | 28.75 | 4.115 | 0.6043 | 49820.4 | 29100000 | 19900000000 | 15300000000000 | 0.3528 | 0.2965 | 0.0222 | 0.0027 | 0.0974 | 0.0054 | 0.2530 | 0.0467 | 0.2085 | 0.0916 | 0.1880 | 0.2163 | 0.1333 | 0.2720 | 0.0496 | 0.1517 | 0.0222 | 0.1086 | 0.0256 | 0.1050 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0025 | 0.0028 | 0.0223 | 0.0206 | 0.0377 | 0.0307 | 0.0289 | 0.0256 | 0.0466 | 0.0365 | 0.8607 | 0.8834 | 0.0005 | 0.0003 | 0.0002 | 0.0005 | 0.0002 | 0.0005 | 0.0059 | 0.0071 | 0.0334 | 0.0374 | 0.0541 | 0.0695 | 0.0498 | 0.0450 | 0.0636 | 0.0730 | 0.7923 | 0.7666 | 0.0002 | 0.0000 | 0.0004 | 0.0042 | 0.0271 | 0.0491 | 0.0391 | 0.0560 | 0.8237 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 402 | 281 | | 5163 | 11094 | 132.9 | 31.75 | 204.40 | 192.72 | 98 | 107 | 114 | 120 | 127 | 135 | 144 | 156 | 174 | 0.0753 | 835 | 1.001 | 90.14 | 24.74 | 1 | 0.0424 | 219 | 0.0024 | 20.29 | 6.351 | 0.2592 | 18683.1 | 2790000 | 443000000 | 75300000000 | 0.4578 | 0.1909 | 0.0003 | 0.0000 | 0.0025 | 0.0000 | 0.0034 | 0.0002 | 0.0224 | 0.0012 | 0.0771 | 0.0208 | 0.1572 | 0.0445 | 0.1683 | 0.0420 | 0.1981 | 0.0794 | 0.3707 | 0.8120 | 0.0002 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0091 | 0.0000 | 0.0343 | 0.0121 | 0.0698 | 0.0263 | 0.0770 | 0.0152 | 0.1062 | 0.0349 | 0.6996 | 0.9115 | 0.0044 | 0.0126 | 0.0142 | 0.0158 | 0.0230 | 0.0536 | 0.0678 | 0.1073 | 0.1497 | 0.1956 | 0.1913 | 0.1546 | 0.1049 | 0.1577 | 0.1355 | 0.1325 | 0.3093 | 0.1703 | 0.0031 | 0.0040 | 0.0108 | 0.0333 | 0.0787 | 0.1393 | 0.1016 | 0.1326 | 0.4966 | 20 | 34 | 61 | 100 | 147 | 198 | 262 | 353 | 492 | 0.0054 | 71.93 | 6.900 | 0.2998 | 78916.5 | 40300000 | 24100000000 | 16000000000000 | 0.4531 | 0.1995 | 0.0210 | 0.0003 | 0.1004 | 0.0108 | 0.2033 | 0.0378 | 0.1881 | 0.0917 | 0.1512 | 0.1677 | 0.1595 | 0.2108 | 0.0921 | 0.1540 | 0.0508 | 0.1423 | 0.0337 | 0.1847 | 0.0004 | 0.0002 | 0.0012 | 0.0020 | 0.0031 | 0.0030 | 0.0172 | 0.0109 | 0.0545 | 0.0442 | 0.0980 | 0.0771 | 0.0764 | 0.0584 | 0.1021 | 0.0867 | 0.6471 | 0.7176 | 0.0011 | 0.0020 | 0.0011 | 0.0023 | 0.0078 | 0.0106 | 0.0300 | 0.0381 | 0.0728 | 0.0866 | 0.1296 | 0.1333 | 0.0923 | 0.0899 | 0.1143 | 0.1148 | 0.5510 | 0.5224 | 0.0007 | 0.0014 | 0.0067 | 0.0219 | 0.0631 | 0.1112 | 0.0841 | 0.1170 | 0.5940 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 655 | 519 | | 12431 | 24620 | 390.0 | 70.08 | 73.02 | 145.52 | 287 | 322 | 350 | 376 | 398 | 418 | 437 | 454 | 476 | 0.0531 | 1307 | 0.717 | 116.71 | 35.11 | 3 | 0.0323 | 401 | 0.0014 | 13.24 | 6.814 | 0.3028 | 157023.0 | 65000000 | 27500000000 | 11900000000000 | 0.4378 | 0.1981 | 0.0007 | 0.0000 | 0.0029 | 0.0000 | 0.0055 | 0.0000 | 0.0115 | 0.0009 | 0.0276 | 0.0098 | 0.0447 | 0.0175 | 0.0492 | 0.0111 | 0.0732 | 0.0171 | 0.7847 | 0.9436 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0000 | 0.0037 | 0.0009 | 0.0122 | 0.0098 | 0.0195 | 0.0175 | 0.0178 | 0.0105 | 0.0271 | 0.0152 | 0.9168 | 0.9461 | 0.0102 | 1.0000 | 0.0215 | 0.0000 | 0.0269 | 0.0000 | 0.0449 | 0.0000 | 0.0682 | 0.0000 | 0.0922 | 0.0000 | 0.0999 | 0.0000 | 0.1191 | 0.0000 | 0.5171 | 0.0000 | 0.0007 | 0.0036 | 0.0042 | 0.0104 | 0.0227 | 0.0348 | 0.0407 | 0.0547 | 0.8282 | 8 | 10 | 11 | 13 | 15 | 20 | 33 | 82 | 218 | 0.1379 | 2.58 | 2.741 | 0.6004 | 26508.4 | 16200000 | 12600000000 | 11400000000000 | 0.6289 | 0.0769 | 0.0413 | 0.0027 | 0.1013 | 0.0182 | 0.1888 | 0.0633 | 0.1750 | 0.0919 | 0.1721 | 0.1461 | 0.1327 | 0.1875 | 0.1013 | 0.1379 | 0.0560 | 0.1347 | 0.0315 | 0.2176 | 0.0002 | 0.0005 | 0.0007 | 0.0006 | 0.0016 | 0.0015 | 0.0123 | 0.0101 | 0.0446 | 0.0428 | 0.0768 | 0.0683 | 0.0519 | 0.0466 | 0.0718 | 0.0703 | 0.7402 | 0.7592 | 0.0004 | 0.0009 | 0.0008 | 0.0018 | 0.0023 | 0.0018 | 0.0159 | 0.0140 | 0.0529 | 0.0605 | 0.0898 | 0.0918 | 0.0567 | 0.0628 | 0.0814 | 0.0868 | 0.6997 | 0.6794 | 0.0004 | 0.0000 | 0.0015 | 0.0114 | 0.0529 | 0.0806 | 0.0550 | 0.0825 | 0.7157 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 824 | 149 | | 3095 | 1375 | 156.7 | 47.45 | 110.15 | 90.82 | 105 | 115 | 124 | 134 | 145 | 160 | 176 | 196 | 227 | 0.3382 | 465 | 1.062 | 83.41 | 29.00 | 1 | 0.0666 | 206 | 0.0014 | 36.35 | 6.808 | 0.1956 | 26798.4 | 4990000 | 1010000000 | 217000000000 | 0.4010 | 0.2369 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0164 | 0.0004 | 0.0622 | 0.0073 | 0.1630 | 0.0383 | 0.2209 | 0.0865 | 0.1773 | 0.0930 | 0.1651 | 0.1290 | 0.1937 | 0.6455 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0066 | 0.0003 | 0.0164 | 0.0033 | 0.0564 | 0.0210 | 0.0986 | 0.0440 | 0.0737 | 0.0367 | 0.1015 | 0.0660 | 0.6458 | 0.8286 | 0.0014 | 0.0026 | 0.0014 | 0.0104 | 0.0096 | 0.0181 | 0.0493 | 0.0907 | 0.1315 | 0.1684 | 0.1685 | 0.1813 | 0.1055 | 0.1192 | 0.1425 | 0.1684 | 0.3904 | 0.2409 | 0.0008 | 0.0000 | 0.0046 | 0.0245 | 0.0772 | 0.1376 | 0.1009 | 0.1223 | 0.5321 | 23 | 34 | 49 | 66 | 79 | 101 | 130 | 181 | 247 | 0.0068 | 27.40 | 5.667 | 0.3730 | 20376.5 | 5090000 | 1510000000 | 502000000000 | 0.4253 | 0.1878 | 0.0226 | 0.0041 | 0.1584 | 0.0225 | 0.2443 | 0.0736 | 0.1493 | 0.0920 | 0.1946 | 0.2086 | 0.1584 | 0.2658 | 0.0588 | 0.1411 | 0.0136 | 0.1022 | 0.0000 | 0.0900 | 0.0000 | 0.0000 | 0.0112 | 0.0048 | 0.0128 | 0.0060 | 0.0400 | 0.0290 | 0.1808 | 0.1351 | 0.2208 | 0.2268 | 0.1120 | 0.1218 | 0.1408 | 0.1375 | 0.2816 | 0.3390 | 0.0050 | 0.0118 | 0.0099 | 0.0147 | 0.0347 | 0.0265 | 0.0743 | 0.0588 | 0.1535 | 0.1971 | 0.2153 | 0.1971 | 0.0990 | 0.1088 | 0.1361 | 0.1412 | 0.2723 | 0.2441 | 0.0039 | 0.0137 | 0.0333 | 0.0412 | 0.1902 | 0.2039 | 0.1000 | 0.1294 | 0.2843 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 715 | 284 | | 4349 | 24088 | 89.5 | 13.78 | 5.43 | 2.07 | 73 | 77 | 80 | 84 | 87 | 91 | 97 | 103 | 109 | 0.0418 | 1008 | 0.588 | 324.65 | 84.85 | 1 | 0.2175 | 946 | 0.0394 | 0.86 | 3.496 | 0.6959 | 8200.8 | 769285 | 73900000 | 7250000000 | 0.4494 | 0.2031 | 0.0008 | 0.0000 | 0.0051 | 0.0000 | 0.0102 | 0.0007 | 0.0254 | 0.0044 | 0.0392 | 0.0120 | 0.0621 | 0.0294 | 0.0708 | 0.0204 | 0.1033 | 0.0328 | 0.6830 | 0.9003 | 0.0005 | 0.0000 | 0.0027 | 0.0000 | 0.0056 | 0.0007 | 0.0144 | 0.0037 | 0.0237 | 0.0115 | 0.0345 | 0.0283 | 0.0362 | 0.0170 | 0.0511 | 0.0255 | 0.8312 | 0.9133 | 0.0183 | 0.0800 | 0.0220 | 0.0800 | 0.0661 | 0.0000 | 0.0771 | 0.2400 | 0.0789 | 0.1600 | 0.0881 | 0.0400 | 0.0844 | 0.2800 | 0.1101 | 0.0400 | 0.4550 | 0.0800 | 0.0079 | 0.0173 | 0.0283 | 0.0336 | 0.0378 | 0.0420 | 0.0535 | 0.0991 | 0.6807 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.5147 | 0.30 | 0.895 | 0.8351 | 33.8 | 231.792 | 1719.99 | 13657.8 | 0.5085 | 0.1610 | 0.0301 | 0.0016 | 0.0914 | 0.0107 | 0.1790 | 0.0368 | 0.2367 | 0.0927 | 0.2312 | 0.1792 | 0.1506 | 0.2518 | 0.0667 | 0.2459 | 0.0126 | 0.1425 | 0.0017 | 0.0387 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0019 | 0.0004 | 0.0124 | 0.0041 | 0.0401 | 0.0133 | 0.1042 | 0.0327 | 0.2310 | 0.0785 | 0.3474 | 0.2650 | 0.2627 | 0.6059 | 0.0142 | 0.0719 | 0.0704 | 0.1807 | 0.1551 | 0.2535 | 0.2061 | 0.2209 | 0.2091 | 0.1486 | 0.1568 | 0.0748 | 0.1088 | 0.0355 | 0.0596 | 0.0115 | 0.0198 | 0.0026 | 0.0004 | 0.0054 | 0.0302 | 0.0848 | 0.1735 | 0.2508 | 0.2509 | 0.1550 | 0.0492 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 121 | 590 | | 6826 | 22797 | 692.3 | 141.16 | 184.25 | 147.65 | 524 | 569 | 603 | 636 | 672 | 711 | 754 | 812 | 894 | 0.0504 | 1149 | 1.195 | 96.01 | 36.50 | 1 | 0.0355 | 242 | 0.0006 | 74.81 | 7.679 | 0.1333 | 499160.0 | 375000000 | 293000000000 | 238000000000000 | 0.4097 | 0.2333 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0033 | 0.0000 | 0.0134 | 0.0015 | 0.0541 | 0.0141 | 0.1179 | 0.0327 | 0.1221 | 0.0242 | 0.1447 | 0.0447 | 0.5439 | 0.8825 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0001 | 0.0244 | 0.0100 | 0.0560 | 0.0208 | 0.0529 | 0.0091 | 0.0796 | 0.0171 | 0.7802 | 0.9428 | 0.0000 | 0.0210 | 0.0059 | 0.0385 | 0.0245 | 0.0559 | 0.0422 | 0.0594 | 0.1114 | 0.1713 | 0.1401 | 0.1608 | 0.1241 | 0.1014 | 0.1595 | 0.1399 | 0.3924 | 0.2517 | 0.0007 | 0.0033 | 0.0052 | 0.0244 | 0.0711 | 0.1157 | 0.0949 | 0.1252 | 0.5596 | 31 | 53 | 80 | 111 | 147 | 188 | 236 | 298 | 396 | 0.0053 | 17.90 | 6.140 | 0.3553 | 55747.2 | 22400000 | 11300000000 | 7040000000000 | 0.4802 | 0.1654 | 0.0189 | 0.0009 | 0.1045 | 0.0065 | 0.1943 | 0.0481 | 0.1712 | 0.0929 | 0.1772 | 0.1570 | 0.1568 | 0.1982 | 0.0804 | 0.1530 | 0.0592 | 0.1463 | 0.0375 | 0.1971 | 0.0006 | 0.0003 | 0.0018 | 0.0010 | 0.0062 | 0.0037 | 0.0214 | 0.0144 | 0.0636 | 0.0533 | 0.1041 | 0.0946 | 0.0826 | 0.0723 | 0.1081 | 0.1001 | 0.6117 | 0.6604 | 0.0021 | 0.0022 | 0.0055 | 0.0077 | 0.0141 | 0.0176 | 0.0366 | 0.0471 | 0.0854 | 0.0843 | 0.1155 | 0.1211 | 0.0905 | 0.0961 | 0.1101 | 0.1108 | 0.5402 | 0.5131 | 0.0011 | 0.0033 | 0.0088 | 0.0271 | 0.0757 | 0.1130 | 0.0967 | 0.1074 | 0.5670 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 166 | 253 | | 6270 | 6263 | 146.8 | 53.83 | 210.83 | 195.38 | 91 | 105 | 116 | 126 | 136 | 148 | 163 | 183 | 214 | 0.1284 | 804 | 0.784 | 97.01 | 20.88 | 2 | 0.0364 | 228 | 0.0012 | 46.26 | 7.074 | 0.1935 | 24453.4 | 4680000 | 1040000000 | 271000000000 | 0.4725 | 0.1765 | 0.0007 | 0.0000 | 0.0042 | 0.0002 | 0.0251 | 0.0014 | 0.0639 | 0.0074 | 0.1432 | 0.0380 | 0.2040 | 0.0897 | 0.1788 | 0.0986 | 0.1596 | 0.1272 | 0.2204 | 0.6374 | 0.0005 | 0.0000 | 0.0007 | 0.0002 | 0.0037 | 0.0007 | 0.0128 | 0.0035 | 0.0536 | 0.0227 | 0.0951 | 0.0435 | 0.0820 | 0.0411 | 0.1203 | 0.0647 | 0.6313 | 0.8237 | 0.0000 | 0.0027 | 0.0028 | 0.0199 | 0.0231 | 0.0292 | 0.0651 | 0.1089 | 0.1254 | 0.1169 | 0.1779 | 0.2058 | 0.1036 | 0.0943 | 0.1359 | 0.1262 | 0.3662 | 0.2961 | 0.0012 | 0.0042 | 0.0089 | 0.0386 | 0.0981 | 0.1463 | 0.1035 | 0.1332 | 0.4660 | 38 | 58 | 81 | 110 | 146 | 193 | 254 | 331 | 478 | 0.0038 | 52.97 | 6.523 | 0.2940 | 82615.2 | 46500000 | 32400000000 | 25600000000000 | 0.5390 | 0.1222 | 0.0251 | 0.0021 | 0.1137 | 0.0098 | 0.2109 | 0.0602 | 0.1891 | 0.0932 | 0.1683 | 0.1720 | 0.1311 | 0.1941 | 0.0678 | 0.1478 | 0.0612 | 0.1313 | 0.0328 | 0.1895 | 0.0004 | 0.0003 | 0.0021 | 0.0012 | 0.0039 | 0.0043 | 0.0189 | 0.0162 | 0.0754 | 0.0638 | 0.1190 | 0.1070 | 0.0829 | 0.0786 | 0.1187 | 0.1041 | 0.5786 | 0.6246 | 0.0011 | 0.0013 | 0.0016 | 0.0040 | 0.0080 | 0.0153 | 0.0366 | 0.0477 | 0.1115 | 0.1194 | 0.1476 | 0.1472 | 0.1041 | 0.1154 | 0.1391 | 0.1366 | 0.4503 | 0.4131 | 0.0009 | 0.0004 | 0.0043 | 0.0272 | 0.0858 | 0.1337 | 0.0923 | 0.1251 | 0.5302 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 438 | 881 | | 789 | 8063 | 74.1 | 31.85 | 47.97 | 131.71 | 30 | 40 | 55 | 65 | 73 | 81 | 92 | 101 | 116 | 0.0633 | 510 | 0.386 | 127.58 | 22.47 | 2 | 0.5982 | 472 | 0.0024 | 38.72 | 6.180 | 0.1858 | 6504.0 | 641928 | 68900000 | 7880000000 | 0.3632 | 0.2507 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0538 | 0.0043 | 0.1000 | 0.0172 | 0.2115 | 0.0948 | 0.1808 | 0.1401 | 0.1846 | 0.1185 | 0.1692 | 0.1789 | 0.0962 | 0.4461 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0135 | 0.0049 | 0.0558 | 0.0395 | 0.0673 | 0.0543 | 0.0635 | 0.0329 | 0.0885 | 0.0625 | 0.7115 | 0.8059 | 0.0000 | 0.0000 | 0.0154 | 0.0139 | 0.0077 | 0.0625 | 0.0346 | 0.0694 | 0.0962 | 0.1319 | 0.1269 | 0.1667 | 0.1038 | 0.1528 | 0.1692 | 0.1250 | 0.4462 | 0.2778 | 0.0026 | 0.0000 | 0.0026 | 0.0179 | 0.0742 | 0.0818 | 0.1023 | 0.1560 | 0.5627 | 11 | 13 | 15 | 16 | 18 | 20 | 22 | 26 | 61 | 0.4823 | 4.88 | 1.769 | 0.8585 | 19647.5 | 17700000 | 20000000000 | 25500000000000 | 0.6771 | 0.1020 | 0.0533 | 0.0311 | 0.1557 | 0.0251 | 0.2172 | 0.0621 | 0.2377 | 0.0932 | 0.2008 | 0.1657 | 0.0820 | 0.2027 | 0.0287 | 0.1686 | 0.0164 | 0.1198 | 0.0082 | 0.1317 | 0.0000 | 0.0147 | 0.0009 | 0.0077 | 0.0046 | 0.0105 | 0.0352 | 0.0252 | 0.0897 | 0.0617 | 0.1175 | 0.0870 | 0.1027 | 0.1024 | 0.1036 | 0.1080 | 0.5458 | 0.5827 | 0.0012 | 0.0013 | 0.0036 | 0.0027 | 0.0060 | 0.0080 | 0.0239 | 0.0213 | 0.1004 | 0.1120 | 0.1470 | 0.1600 | 0.1016 | 0.0973 | 0.1147 | 0.1307 | 0.5018 | 0.4667 | 0.0000 | 0.0011 | 0.0074 | 0.0253 | 0.1077 | 0.1267 | 0.0940 | 0.1109 | 0.5269 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 347 | | 5602 | 6122 | 469.4 | 79.21 | 27.49 | 47.62 | 357 | 396 | 427 | 455 | 479 | 496 | 513 | 531 | 559 | 0.1042 | 638 | 0.998 | 133.18 | 37.86 | 1 | 0.0605 | 339 | 0.0017 | 16.11 | 6.642 | 0.3084 | 226643.0 | 112000000 | 57000000000 | 29500000000000 | 0.4201 | 0.2305 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0000 | 0.0068 | 0.0007 | 0.0224 | 0.0104 | 0.0352 | 0.0294 | 0.0373 | 0.0137 | 0.0623 | 0.0225 | 0.8308 | 0.9233 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0025 | 0.0000 | 0.0042 | 0.0005 | 0.0136 | 0.0097 | 0.0247 | 0.0272 | 0.0207 | 0.0098 | 0.0262 | 0.0177 | 0.9067 | 0.9351 | 0.0187 | 0.0000 | 0.0093 | 0.0541 | 0.0093 | 0.0811 | 0.0318 | 0.1622 | 0.0486 | 0.1892 | 0.0542 | 0.1892 | 0.0710 | 0.0811 | 0.0841 | 0.1351 | 0.6729 | 0.1081 | 0.0000 | 0.0020 | 0.0049 | 0.0120 | 0.0273 | 0.0462 | 0.0524 | 0.0908 | 0.7645 | 8 | 10 | 12 | 14 | 15 | 17 | 20 | 29 | 50 | 0.3237 | 1.45 | 2.056 | 0.8309 | 3023.4 | 1020000 | 532000000 | 337000000000 | 0.5358 | 0.1270 | 0.0965 | 0.0392 | 0.0856 | 0.0530 | 0.0911 | 0.0723 | 0.1111 | 0.0933 | 0.1840 | 0.1154 | 0.1858 | 0.1198 | 0.1056 | 0.1375 | 0.1093 | 0.1452 | 0.0310 | 0.2242 | 0.0300 | 0.0239 | 0.0257 | 0.0316 | 0.0178 | 0.0421 | 0.0165 | 0.0541 | 0.0484 | 0.0733 | 0.0772 | 0.0824 | 0.0502 | 0.0798 | 0.0876 | 0.0900 | 0.6467 | 0.5229 | 0.0018 | 0.0011 | 0.0092 | 0.0063 | 0.0111 | 0.0138 | 0.0129 | 0.0180 | 0.0563 | 0.0624 | 0.0969 | 0.0963 | 0.0572 | 0.0709 | 0.0895 | 0.1270 | 0.6651 | 0.6042 | 0.0092 | 0.0077 | 0.0061 | 0.0146 | 0.0452 | 0.0958 | 0.0598 | 0.0782 | 0.6835 |