High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 77 | 299 | | 362 | 804 | 84.7 | 13.26 | 9.06 | 3.12 | 65 | 72 | 78 | 84 | 87 | 90 | 93 | 96 | 100 | 0.2786 | 224 | 0.728 | 31.40 | 8.49 | 1 | 0.2459 | 89 | 0.0508 | 1.25 | 3.272 | 0.6191 | 7352.5 | 651714 | 58800000 | 5400000000 | 0.3674 | 0.2592 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0351 | 0.0028 | 0.0596 | 0.0442 | 0.1053 | 0.0912 | 0.1368 | 0.0276 | 0.1825 | 0.0608 | 0.4737 | 0.7735 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0000 | 0.0256 | 0.0028 | 0.0415 | 0.0442 | 0.0607 | 0.0912 | 0.0607 | 0.0276 | 0.0799 | 0.0608 | 0.7252 | 0.7735 | 0.0714 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.1429 | 0.0000 | 0.2143 | 0.0000 | 0.1786 | 0.0000 | 0.0357 | 0.0000 | 0.1071 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0242 | 0.0338 | 0.0725 | 0.0725 | 0.0966 | 0.1401 | 0.5556 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 0.0140 | 20.20 | 4.617 | 0.2555 | 91.8 | 1010.84 | 11937.1 | 150060 | 0.5369 | 0.1144 | 0.0442 | 0.0017 | 0.1633 | 0.0034 | 0.2449 | 0.0458 | 0.2415 | 0.1171 | 0.1565 | 0.1460 | 0.0884 | 0.2530 | 0.0476 | 0.2054 | 0.0102 | 0.1562 | 0.0034 | 0.0713 | 0.0018 | 0.0000 | 0.0235 | 0.0000 | 0.0470 | 0.0056 | 0.1302 | 0.0405 | 0.2061 | 0.1103 | 0.2188 | 0.1494 | 0.2116 | 0.1955 | 0.1157 | 0.2598 | 0.0452 | 0.2388 | 0.1042 | 0.3150 | 0.2008 | 0.3858 | 0.2124 | 0.2283 | 0.2432 | 0.0394 | 0.1236 | 0.0315 | 0.0811 | 0.0000 | 0.0270 | 0.0000 | 0.0077 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0424 | 0.1038 | 0.2076 | 0.2182 | 0.1801 | 0.1547 | 0.0657 | 0.0233 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1047 | 808 | | 11793 | 29672 | 113.4 | 29.34 | 199.72 | 175.90 | 81 | 89 | 96 | 102 | 108 | 115 | 124 | 135 | 153 | 0.0534 | 1583 | 0.454 | 192.20 | 38.59 | 5 | 0.0484 | 571 | 0.0029 | 15.86 | 6.239 | 0.2893 | 13720.4 | 1780000 | 247000000 | 36900000000 | 0.5494 | 0.1414 | 0.0009 | 0.0000 | 0.0048 | 0.0002 | 0.0148 | 0.0015 | 0.0418 | 0.0067 | 0.0987 | 0.0255 | 0.1564 | 0.0610 | 0.1565 | 0.0585 | 0.1823 | 0.0902 | 0.3439 | 0.7563 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0052 | 0.0007 | 0.0169 | 0.0038 | 0.0447 | 0.0139 | 0.0787 | 0.0369 | 0.0757 | 0.0239 | 0.1044 | 0.0426 | 0.6722 | 0.8779 | 0.0055 | 0.0043 | 0.0115 | 0.0182 | 0.0243 | 0.0503 | 0.0545 | 0.1146 | 0.1261 | 0.1767 | 0.1530 | 0.1734 | 0.1129 | 0.1199 | 0.1500 | 0.1370 | 0.3622 | 0.2056 | 0.0035 | 0.0069 | 0.0125 | 0.0420 | 0.0881 | 0.1219 | 0.1128 | 0.1261 | 0.4861 | 21 | 40 | 70 | 109 | 156 | 208 | 264 | 334 | 444 | 0.0045 | 62.50 | 7.035 | 0.2736 | 70826.1 | 33200000 | 18700000000 | 12000000000000 | 0.4909 | 0.1748 | 0.0241 | 0.0016 | 0.1156 | 0.0080 | 0.2373 | 0.0460 | 0.1905 | 0.1069 | 0.1697 | 0.1785 | 0.1335 | 0.2098 | 0.0719 | 0.1527 | 0.0399 | 0.1470 | 0.0174 | 0.1495 | 0.0004 | 0.0002 | 0.0009 | 0.0011 | 0.0042 | 0.0023 | 0.0126 | 0.0094 | 0.0581 | 0.0468 | 0.1027 | 0.0856 | 0.0862 | 0.0727 | 0.1139 | 0.0958 | 0.6211 | 0.6861 | 0.0010 | 0.0011 | 0.0048 | 0.0062 | 0.0108 | 0.0147 | 0.0306 | 0.0373 | 0.0810 | 0.0966 | 0.1391 | 0.1521 | 0.1107 | 0.1138 | 0.1321 | 0.1356 | 0.4899 | 0.4427 | 0.0002 | 0.0024 | 0.0061 | 0.0189 | 0.0699 | 0.1259 | 0.0994 | 0.1257 | 0.5515 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 994 | 366 | | 5578 | 9502 | 439.0 | 109.23 | 7.27 | 7.81 | 292 | 342 | 380 | 410 | 440 | 471 | 499 | 532 | 577 | 0.0764 | 726 | 0.939 | 87.10 | 28.18 | 1 | 0.0446 | 249 | 0.0007 | 54.37 | 7.463 | 0.1610 | 204683.0 | 101000000 | 51800000000 | 27900000000000 | 0.4190 | 0.2212 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0035 | 0.0004 | 0.0227 | 0.0026 | 0.0796 | 0.0200 | 0.1332 | 0.0381 | 0.1486 | 0.0495 | 0.1674 | 0.0707 | 0.4438 | 0.8187 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0004 | 0.0055 | 0.0021 | 0.0249 | 0.0145 | 0.0386 | 0.0203 | 0.0420 | 0.0202 | 0.0598 | 0.0259 | 0.8277 | 0.9167 | 0.0025 | 0.0150 | 0.0083 | 0.0300 | 0.0108 | 0.0936 | 0.0717 | 0.1685 | 0.1350 | 0.1648 | 0.1983 | 0.1985 | 0.1250 | 0.0749 | 0.1433 | 0.0599 | 0.3050 | 0.1948 | 0.0011 | 0.0014 | 0.0018 | 0.0164 | 0.0513 | 0.0969 | 0.0840 | 0.1033 | 0.6439 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.3430 | 0.51 | 1.198 | 0.7294 | 113.9 | 6884.51 | 785459 | 106000000 | 0.5832 | 0.1225 | 0.0192 | 0.0019 | 0.0770 | 0.0156 | 0.1579 | 0.0462 | 0.2263 | 0.1039 | 0.2280 | 0.1979 | 0.1695 | 0.2473 | 0.0885 | 0.2176 | 0.0290 | 0.1308 | 0.0047 | 0.0389 | 0.0061 | 0.0001 | 0.0245 | 0.0052 | 0.0678 | 0.0214 | 0.1121 | 0.0524 | 0.1595 | 0.1246 | 0.1671 | 0.1799 | 0.1649 | 0.2137 | 0.1572 | 0.2103 | 0.1408 | 0.1925 | 0.1745 | 0.1950 | 0.1707 | 0.1376 | 0.1329 | 0.1217 | 0.1097 | 0.1088 | 0.0929 | 0.0945 | 0.0843 | 0.0801 | 0.0659 | 0.0748 | 0.0751 | 0.0786 | 0.0940 | 0.1088 | 0.0231 | 0.0695 | 0.1299 | 0.1560 | 0.1619 | 0.1493 | 0.1157 | 0.0965 | 0.0981 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 332 | 897 | | 4130 | 6420 | 525.0 | 190.33 | 45.50 | 77.20 | 256 | 314 | 388 | 474 | 542 | 599 | 659 | 716 | 767 | 0.1092 | 701 | 0.638 | 84.10 | 14.14 | 5 | 0.0482 | 199 | 0.0007 | 53.48 | 7.439 | 0.1929 | 311857.0 | 201000000 | 138000000000 | 98300000000000 | 0.3906 | 0.2301 | 0.0000 | 0.0015 | 0.0031 | 0.0011 | 0.0168 | 0.0011 | 0.0291 | 0.0083 | 0.1034 | 0.0496 | 0.1516 | 0.0931 | 0.1309 | 0.0644 | 0.1072 | 0.0966 | 0.4579 | 0.6842 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0018 | 0.0328 | 0.0255 | 0.0470 | 0.0436 | 0.0303 | 0.0252 | 0.0445 | 0.0370 | 0.8418 | 0.8670 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0021 | 0.0167 | 0.0104 | 0.0410 | 0.0494 | 0.0819 | 0.0626 | 0.1335 | 0.0494 | 0.1108 | 0.0745 | 0.1457 | 0.7516 | 0.4643 | 0.0000 | 0.0005 | 0.0005 | 0.0045 | 0.0352 | 0.0587 | 0.0352 | 0.0564 | 0.8090 | 8 | 10 | 13 | 15 | 17 | 22 | 31 | 60 | 119 | 0.0622 | 10.67 | 3.904 | 0.6364 | 8028.7 | 3400000 | 2280000000 | 1870000000000 | 0.5362 | 0.1440 | 0.0369 | 0.0169 | 0.0844 | 0.0226 | 0.1082 | 0.0463 | 0.1504 | 0.0993 | 0.1847 | 0.1366 | 0.1821 | 0.1061 | 0.1372 | 0.1163 | 0.0976 | 0.1558 | 0.0185 | 0.3002 | 0.0017 | 0.0057 | 0.0034 | 0.0076 | 0.0040 | 0.0086 | 0.0115 | 0.0195 | 0.0453 | 0.0437 | 0.0539 | 0.0518 | 0.0441 | 0.0456 | 0.0648 | 0.0699 | 0.7713 | 0.7476 | 0.0007 | 0.0025 | 0.0029 | 0.0016 | 0.0102 | 0.0074 | 0.0154 | 0.0164 | 0.0469 | 0.0402 | 0.0608 | 0.0731 | 0.0490 | 0.0484 | 0.0791 | 0.0649 | 0.7350 | 0.7455 | 0.0006 | 0.0051 | 0.0058 | 0.0135 | 0.0398 | 0.0630 | 0.0424 | 0.0694 | 0.7603 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1153 | 647 | | 7001 | 25505 | 556.6 | 122.04 | 346.05 | 471.05 | 401 | 439 | 476 | 515 | 554 | 594 | 633 | 670 | 719 | 0.0502 | 1281 | 1.091 | 94.40 | 31.32 | 2 | 0.0330 | 231 | 0.0008 | 49.47 | 7.389 | 0.1879 | 324688.0 | 198000000 | 125000000000 | 81200000000000 | 0.4396 | 0.2100 | 0.0007 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0002 | 0.0176 | 0.0008 | 0.0856 | 0.0167 | 0.1397 | 0.0345 | 0.1231 | 0.0336 | 0.1667 | 0.0500 | 0.4597 | 0.8643 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0003 | 0.0329 | 0.0127 | 0.0559 | 0.0246 | 0.0475 | 0.0180 | 0.0714 | 0.0252 | 0.7845 | 0.9193 | 0.0042 | 0.0190 | 0.0042 | 0.0521 | 0.0140 | 0.0474 | 0.0524 | 0.1232 | 0.1054 | 0.1943 | 0.1795 | 0.1848 | 0.1194 | 0.1327 | 0.1522 | 0.1137 | 0.3687 | 0.1327 | 0.0000 | 0.0026 | 0.0017 | 0.0185 | 0.0503 | 0.0888 | 0.0772 | 0.0943 | 0.6665 | 16 | 30 | 58 | 98 | 145 | 207 | 334 | 573 | 1040 | 0.0125 | 72.60 | 6.612 | 0.3697 | 341631.0 | 484000000 | 806000000000 | 1.47E+15 | 0.3657 | 0.3010 | 0.0271 | 0.0034 | 0.1024 | 0.0083 | 0.1982 | 0.0464 | 0.1992 | 0.1091 | 0.1937 | 0.1605 | 0.1274 | 0.2005 | 0.0763 | 0.1440 | 0.0457 | 0.1451 | 0.0301 | 0.1828 | 0.0006 | 0.0011 | 0.0022 | 0.0019 | 0.0049 | 0.0048 | 0.0175 | 0.0174 | 0.0458 | 0.0451 | 0.0736 | 0.0727 | 0.0584 | 0.0567 | 0.0751 | 0.0729 | 0.7219 | 0.7275 | 0.0005 | 0.0012 | 0.0032 | 0.0039 | 0.0065 | 0.0072 | 0.0159 | 0.0166 | 0.0490 | 0.0479 | 0.0772 | 0.0773 | 0.0599 | 0.0636 | 0.0830 | 0.0742 | 0.7047 | 0.7080 | 0.0005 | 0.0031 | 0.0048 | 0.0174 | 0.0468 | 0.0729 | 0.0592 | 0.0760 | 0.7193 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 140 | | 4015 | 11442 | 298.5 | 93.89 | 283.49 | 327.91 | 188 | 224 | 248 | 270 | 290 | 313 | 337 | 371 | 423 | 0.0718 | 821 | 0.641 | 110.89 | 16.16 | 3 | 0.0590 | 237 | 0.0005 | 119.77 | 7.721 | 0.1137 | 97912.3 | 34900000 | 13400000000 | 5490000000000 | 0.4228 | 0.1994 | 0.0000 | 0.0000 | 0.0005 | 0.0003 | 0.0078 | 0.0000 | 0.0352 | 0.0049 | 0.0906 | 0.0391 | 0.1684 | 0.0564 | 0.1361 | 0.0524 | 0.1522 | 0.0795 | 0.4092 | 0.7675 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0135 | 0.0016 | 0.0347 | 0.0237 | 0.0663 | 0.0307 | 0.0579 | 0.0234 | 0.0710 | 0.0373 | 0.7547 | 0.8833 | 0.0011 | 0.0093 | 0.0032 | 0.0023 | 0.0086 | 0.0163 | 0.0452 | 0.0629 | 0.0893 | 0.0979 | 0.1453 | 0.1375 | 0.0969 | 0.1235 | 0.1163 | 0.1142 | 0.4941 | 0.4359 | 0.0005 | 0.0005 | 0.0032 | 0.0244 | 0.0684 | 0.1087 | 0.0976 | 0.1124 | 0.5843 | 18 | 23 | 31 | 69 | 150 | 246 | 370 | 532 | 762 | 0.0260 | 64.88 | 6.232 | 0.4074 | 187886.0 | 166000000 | 173000000000 | 201000000000000 | 0.6183 | 0.1150 | 0.0315 | 0.0018 | 0.0954 | 0.0093 | 0.2028 | 0.0466 | 0.1778 | 0.0888 | 0.1759 | 0.1607 | 0.1389 | 0.1793 | 0.0880 | 0.1474 | 0.0528 | 0.1482 | 0.0370 | 0.2179 | 0.0008 | 0.0000 | 0.0015 | 0.0004 | 0.0054 | 0.0022 | 0.0149 | 0.0104 | 0.0492 | 0.0440 | 0.0677 | 0.0593 | 0.0620 | 0.0557 | 0.0989 | 0.0825 | 0.6996 | 0.7454 | 0.0014 | 0.0000 | 0.0038 | 0.0019 | 0.0049 | 0.0074 | 0.0181 | 0.0211 | 0.0585 | 0.0692 | 0.0937 | 0.0977 | 0.0766 | 0.0922 | 0.1110 | 0.1151 | 0.6320 | 0.5954 | 0.0005 | 0.0026 | 0.0062 | 0.0133 | 0.0554 | 0.0778 | 0.0700 | 0.1011 | 0.6730 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 307 | 284 | | 4454 | 15705 | 541.8 | 126.10 | 114.66 | 191.51 | 395 | 434 | 463 | 491 | 521 | 551 | 591 | 651 | 728 | 0.0554 | 870 | 1.060 | 102.88 | 27.59 | 2 | 0.0534 | 238 | 0.0008 | 82.33 | 7.369 | 0.1665 | 309466.0 | 186000000 | 118000000000 | 78000000000000 | 0.4066 | 0.2345 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0005 | 0.0157 | 0.0027 | 0.0737 | 0.0261 | 0.1377 | 0.0438 | 0.1448 | 0.0443 | 0.1534 | 0.0597 | 0.4611 | 0.8229 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0056 | 0.0002 | 0.0407 | 0.0161 | 0.0709 | 0.0258 | 0.0709 | 0.0192 | 0.0895 | 0.0269 | 0.7210 | 0.9117 | 0.0022 | 0.0032 | 0.0000 | 0.0160 | 0.0078 | 0.0415 | 0.0526 | 0.0927 | 0.0973 | 0.1629 | 0.1353 | 0.1502 | 0.0839 | 0.1086 | 0.1074 | 0.1438 | 0.5134 | 0.2812 | 0.0000 | 0.0031 | 0.0062 | 0.0333 | 0.0868 | 0.1149 | 0.1004 | 0.1108 | 0.5445 | 5 | 7 | 8 | 10 | 11 | 17 | 98 | 220 | 400 | 0.1818 | 28.75 | 4.115 | 0.6043 | 49820.4 | 29100000 | 19900000000 | 15300000000000 | 0.3528 | 0.2965 | 0.0222 | 0.0027 | 0.0974 | 0.0054 | 0.2530 | 0.0467 | 0.2085 | 0.0916 | 0.1880 | 0.2163 | 0.1333 | 0.2720 | 0.0496 | 0.1517 | 0.0222 | 0.1086 | 0.0256 | 0.1050 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0025 | 0.0028 | 0.0223 | 0.0206 | 0.0377 | 0.0307 | 0.0289 | 0.0256 | 0.0466 | 0.0365 | 0.8607 | 0.8834 | 0.0005 | 0.0003 | 0.0002 | 0.0005 | 0.0002 | 0.0005 | 0.0059 | 0.0071 | 0.0334 | 0.0374 | 0.0541 | 0.0695 | 0.0498 | 0.0450 | 0.0636 | 0.0730 | 0.7923 | 0.7666 | 0.0002 | 0.0000 | 0.0004 | 0.0042 | 0.0271 | 0.0491 | 0.0391 | 0.0560 | 0.8237 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 547 | 120 | | 5210 | 7031 | 116.5 | 33.51 | 67.29 | 88.49 | 82 | 90 | 96 | 102 | 109 | 116 | 126 | 140 | 161 | 0.1074 | 755 | 0.962 | 86.27 | 33.84 | 2 | 0.0478 | 249 | 0.0029 | 20.97 | 6.262 | 0.2723 | 14702.5 | 2030000 | 306000000 | 50600000000 | 0.4062 | 0.2387 | 0.0018 | 0.0000 | 0.0032 | 0.0000 | 0.0093 | 0.0009 | 0.0370 | 0.0017 | 0.1025 | 0.0273 | 0.1787 | 0.0577 | 0.1630 | 0.0624 | 0.1798 | 0.0955 | 0.3247 | 0.7545 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0044 | 0.0004 | 0.0154 | 0.0008 | 0.0427 | 0.0160 | 0.0740 | 0.0248 | 0.0717 | 0.0220 | 0.1040 | 0.0419 | 0.6847 | 0.8941 | 0.0019 | 0.0042 | 0.0049 | 0.0166 | 0.0165 | 0.0374 | 0.0525 | 0.0832 | 0.1380 | 0.1933 | 0.1672 | 0.2121 | 0.1263 | 0.0894 | 0.1545 | 0.1538 | 0.3382 | 0.2100 | 0.0039 | 0.0048 | 0.0101 | 0.0400 | 0.0761 | 0.1094 | 0.1104 | 0.1359 | 0.5094 | 12 | 15 | 20 | 26 | 33 | 43 | 64 | 100 | 163 | 0.0295 | 19.01 | 4.722 | 0.5549 | 12357.0 | 4090000 | 1840000000 | 978000000000 | 0.7256 | 0.0616 | 0.0176 | 0.0062 | 0.0821 | 0.0241 | 0.1437 | 0.0469 | 0.1935 | 0.0841 | 0.1686 | 0.1496 | 0.1569 | 0.1695 | 0.0997 | 0.1447 | 0.0982 | 0.1371 | 0.0396 | 0.2378 | 0.0025 | 0.0024 | 0.0050 | 0.0041 | 0.0103 | 0.0111 | 0.0227 | 0.0199 | 0.0900 | 0.0827 | 0.1399 | 0.1253 | 0.0929 | 0.0918 | 0.1312 | 0.1236 | 0.5056 | 0.5392 | 0.0011 | 0.0020 | 0.0092 | 0.0033 | 0.0075 | 0.0139 | 0.0316 | 0.0463 | 0.1086 | 0.1026 | 0.1580 | 0.1794 | 0.1080 | 0.1112 | 0.1356 | 0.1456 | 0.4406 | 0.3958 | 0.0034 | 0.0034 | 0.0112 | 0.0244 | 0.0937 | 0.1541 | 0.0941 | 0.1332 | 0.4824 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 441 | 830 | | 4757 | 10543 | 286.6 | 105.44 | 372.79 | 417.10 | 125 | 169 | 222 | 270 | 315 | 343 | 363 | 383 | 408 | 0.0672 | 708 | 1.208 | 96.84 | 36.89 | 2 | 0.0526 | 250 | 0.0009 | 30.90 | 7.255 | 0.1963 | 93264.4 | 32700000 | 12000000000 | 4520000000000 | 0.3736 | 0.2485 | 0.0021 | 0.0000 | 0.0078 | 0.0000 | 0.0135 | 0.0025 | 0.0526 | 0.0072 | 0.1294 | 0.0416 | 0.1585 | 0.0782 | 0.1407 | 0.0682 | 0.1819 | 0.1216 | 0.3134 | 0.6807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0046 | 0.0019 | 0.0255 | 0.0172 | 0.0304 | 0.0316 | 0.0264 | 0.0207 | 0.0350 | 0.0340 | 0.8780 | 0.8947 | 0.0022 | 0.0105 | 0.0022 | 0.0122 | 0.0092 | 0.0385 | 0.0189 | 0.0769 | 0.0415 | 0.1486 | 0.0739 | 0.1766 | 0.0922 | 0.1276 | 0.1305 | 0.1678 | 0.6295 | 0.2413 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0260 | 0.0290 | 0.0297 | 0.0405 | 0.8684 | 20 | 29 | 48 | 102 | 197 | 329 | 504 | 714 | 1008 | 0.0138 | 104.97 | 6.639 | 0.3555 | 312926.0 | 340000000 | 425000000000 | 584000000000000 | 0.4678 | 0.1840 | 0.0316 | 0.0015 | 0.1275 | 0.0045 | 0.2614 | 0.0469 | 0.1743 | 0.0888 | 0.1536 | 0.1997 | 0.1373 | 0.2093 | 0.0632 | 0.1533 | 0.0316 | 0.1241 | 0.0196 | 0.1720 | 0.0000 | 0.0002 | 0.0009 | 0.0002 | 0.0020 | 0.0002 | 0.0098 | 0.0050 | 0.0431 | 0.0439 | 0.0803 | 0.0605 | 0.0592 | 0.0447 | 0.0801 | 0.0768 | 0.7247 | 0.7686 | 0.0003 | 0.0003 | 0.0006 | 0.0029 | 0.0026 | 0.0052 | 0.0149 | 0.0147 | 0.0584 | 0.0700 | 0.1094 | 0.1201 | 0.0788 | 0.0851 | 0.1186 | 0.1378 | 0.6164 | 0.5638 | 0.0000 | 0.0005 | 0.0018 | 0.0084 | 0.0562 | 0.0893 | 0.0659 | 0.1043 | 0.6735 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 607 | 425 | | 710 | 2523 | 137.3 | 19.50 | 92.60 | 84.78 | 108 | 118 | 127 | 136 | 142 | 146 | 151 | 155 | 160 | 0.1550 | 391 | 0.898 | 77.52 | 25.50 | 1 | 0.3000 | 213 | 0.0194 | 2.48 | 4.222 | 0.5165 | 19229.6 | 2740000 | 397000000 | 58100000000 | 0.3917 | 0.2405 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0028 | 0.0547 | 0.0310 | 0.0547 | 0.0648 | 0.0813 | 0.0254 | 0.1360 | 0.0394 | 0.6617 | 0.8366 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0111 | 0.0028 | 0.0446 | 0.0310 | 0.0350 | 0.0648 | 0.0398 | 0.0254 | 0.0653 | 0.0394 | 0.8041 | 0.8366 | 0.1200 | 0.0000 | 0.2000 | 0.0000 | 0.3200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0290 | 0.0338 | 0.0531 | 0.0628 | 0.0773 | 0.7440 | 21 | 29 | 40 | 53 | 69 | 84 | 105 | 131 | 195 | 0.0217 | 5.49 | 4.593 | 0.5505 | 15759.1 | 4090000 | 1360000000 | 524000000000 | 0.5327 | 0.1397 | 0.0216 | 0.0021 | 0.0747 | 0.0164 | 0.0943 | 0.0472 | 0.1179 | 0.0626 | 0.1473 | 0.1067 | 0.1866 | 0.1456 | 0.1218 | 0.1292 | 0.1257 | 0.1518 | 0.1100 | 0.3385 | 0.0000 | 0.0014 | 0.0085 | 0.0041 | 0.0136 | 0.0135 | 0.0298 | 0.0230 | 0.0562 | 0.0594 | 0.1285 | 0.0939 | 0.0809 | 0.0689 | 0.1260 | 0.1060 | 0.5566 | 0.6300 | 0.0030 | 0.0099 | 0.0120 | 0.0059 | 0.0150 | 0.0198 | 0.0435 | 0.0435 | 0.0901 | 0.1087 | 0.1667 | 0.1601 | 0.0901 | 0.1186 | 0.1396 | 0.1719 | 0.4399 | 0.3617 | 0.0056 | 0.0134 | 0.0134 | 0.0335 | 0.0838 | 0.1173 | 0.1039 | 0.1363 | 0.4927 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 445 | 885 | | 6720 | 10576 | 145.0 | 36.97 | 295.37 | 234.47 | 104 | 115 | 123 | 131 | 139 | 148 | 158 | 172 | 194 | 0.1029 | 1088 | 0.626 | 198.72 | 50.01 | 1 | 0.0999 | 671 | 0.0017 | 31.55 | 6.712 | 0.2250 | 22380.3 | 3690000 | 653000000 | 124000000000 | 0.4622 | 0.1938 | 0.0005 | 0.0000 | 0.0030 | 0.0002 | 0.0103 | 0.0013 | 0.0323 | 0.0038 | 0.0867 | 0.0230 | 0.1608 | 0.0551 | 0.1817 | 0.0633 | 0.1822 | 0.0935 | 0.3425 | 0.7598 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0023 | 0.0009 | 0.0120 | 0.0021 | 0.0362 | 0.0137 | 0.0734 | 0.0334 | 0.0766 | 0.0241 | 0.1038 | 0.0442 | 0.6935 | 0.8815 | 0.0071 | 0.0081 | 0.0063 | 0.0444 | 0.0205 | 0.0282 | 0.0947 | 0.1290 | 0.1539 | 0.1673 | 0.1902 | 0.1714 | 0.1200 | 0.0968 | 0.1350 | 0.1310 | 0.2723 | 0.2238 | 0.0007 | 0.0044 | 0.0119 | 0.0408 | 0.0983 | 0.1353 | 0.1272 | 0.1452 | 0.4362 | 37 | 76 | 126 | 181 | 247 | 316 | 392 | 484 | 624 | 0.0023 | 85.50 | 7.315 | 0.2151 | 142212.0 | 87400000 | 63000000000 | 51000000000000 | 0.5432 | 0.1364 | 0.0279 | 0.0023 | 0.1381 | 0.0113 | 0.2587 | 0.0476 | 0.1904 | 0.1232 | 0.1774 | 0.1886 | 0.1211 | 0.2083 | 0.0551 | 0.1398 | 0.0244 | 0.1359 | 0.0068 | 0.1429 | 0.0004 | 0.0002 | 0.0022 | 0.0026 | 0.0044 | 0.0034 | 0.0196 | 0.0138 | 0.0714 | 0.0585 | 0.1250 | 0.1079 | 0.1052 | 0.0792 | 0.1248 | 0.1135 | 0.5471 | 0.6207 | 0.0022 | 0.0031 | 0.0054 | 0.0083 | 0.0165 | 0.0211 | 0.0326 | 0.0418 | 0.0979 | 0.1017 | 0.1600 | 0.1663 | 0.1128 | 0.1228 | 0.1279 | 0.1459 | 0.4447 | 0.3890 | 0.0009 | 0.0046 | 0.0110 | 0.0265 | 0.0867 | 0.1423 | 0.1125 | 0.1244 | 0.4912 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1121 | 451 | | 6463 | 8308 | 92.4 | 21.14 | 64.20 | 58.22 | 68 | 75 | 80 | 85 | 90 | 96 | 102 | 109 | 121 | 0.1133 | 941 | 0.502 | 162.61 | 33.73 | 3 | 0.0791 | 511 | 0.0045 | 8.67 | 5.719 | 0.3500 | 8980.8 | 917146 | 98200000 | 11000000000 | 0.4709 | 0.1844 | 0.0005 | 0.0000 | 0.0056 | 0.0000 | 0.0071 | 0.0007 | 0.0282 | 0.0044 | 0.0803 | 0.0230 | 0.1265 | 0.0487 | 0.1496 | 0.0470 | 0.1916 | 0.0838 | 0.4105 | 0.7925 | 0.0004 | 0.0000 | 0.0034 | 0.0000 | 0.0032 | 0.0003 | 0.0129 | 0.0024 | 0.0336 | 0.0144 | 0.0546 | 0.0290 | 0.0643 | 0.0214 | 0.0936 | 0.0415 | 0.7341 | 0.8910 | 0.0041 | 0.0140 | 0.0156 | 0.0420 | 0.0303 | 0.0812 | 0.0705 | 0.0980 | 0.1115 | 0.1765 | 0.1566 | 0.2185 | 0.1393 | 0.1176 | 0.1377 | 0.1289 | 0.3344 | 0.1232 | 0.0042 | 0.0088 | 0.0152 | 0.0412 | 0.0629 | 0.0960 | 0.0973 | 0.1255 | 0.5490 | 12 | 17 | 24 | 31 | 41 | 58 | 79 | 110 | 150 | 0.0333 | 4.43 | 4.417 | 0.5777 | 7511.6 | 1200000 | 227000000 | 48400000000 | 0.5963 | 0.1028 | 0.0286 | 0.0119 | 0.1026 | 0.0162 | 0.1765 | 0.0476 | 0.1913 | 0.1232 | 0.1647 | 0.1645 | 0.1479 | 0.1992 | 0.1016 | 0.1403 | 0.0572 | 0.1417 | 0.0296 | 0.1555 | 0.0025 | 0.0049 | 0.0042 | 0.0042 | 0.0053 | 0.0084 | 0.0181 | 0.0298 | 0.0577 | 0.0498 | 0.0936 | 0.0780 | 0.0747 | 0.0703 | 0.1234 | 0.1059 | 0.6206 | 0.6487 | 0.0019 | 0.0023 | 0.0058 | 0.0027 | 0.0089 | 0.0119 | 0.0314 | 0.0337 | 0.0823 | 0.0958 | 0.1366 | 0.1500 | 0.1029 | 0.1031 | 0.1300 | 0.1404 | 0.5000 | 0.4601 | 0.0019 | 0.0010 | 0.0088 | 0.0237 | 0.0703 | 0.1144 | 0.0930 | 0.1433 | 0.5436 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1152 | 223 | | 1691 | 12352 | 99.2 | 17.11 | 46.92 | 69.30 | 79 | 84 | 88 | 92 | 96 | 101 | 107 | 114 | 124 | 0.0508 | 627 | 1.190 | 91.98 | 34.23 | 1 | 0.1366 | 231 | 0.0065 | 7.72 | 5.324 | 0.3702 | 10134.8 | 1070000 | 116000000 | 12900000000 | 0.3875 | 0.2575 | 0.0008 | 0.0000 | 0.0040 | 0.0000 | 0.0127 | 0.0000 | 0.0343 | 0.0024 | 0.0741 | 0.0253 | 0.1076 | 0.0519 | 0.1139 | 0.0404 | 0.1777 | 0.0821 | 0.4749 | 0.7978 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0047 | 0.0000 | 0.0206 | 0.0018 | 0.0419 | 0.0231 | 0.0599 | 0.0420 | 0.0573 | 0.0213 | 0.0879 | 0.0390 | 0.7264 | 0.8729 | 0.0121 | 0.1176 | 0.0040 | 0.1765 | 0.0526 | 0.2353 | 0.0931 | 0.2941 | 0.1336 | 0.1176 | 0.1903 | 0.0588 | 0.1579 | 0.0000 | 0.1741 | 0.0000 | 0.1822 | 0.0000 | 0.0039 | 0.0065 | 0.0310 | 0.0233 | 0.0802 | 0.1125 | 0.1035 | 0.1475 | 0.4916 | 7 | 10 | 13 | 17 | 23 | 32 | 44 | 64 | 112 | 0.0318 | 9.40 | 4.580 | 0.5581 | 7003.8 | 2350000 | 1290000000 | 919000000000 | 0.6011 | 0.1309 | 0.0239 | 0.0061 | 0.0710 | 0.0163 | 0.1253 | 0.0476 | 0.1857 | 0.0850 | 0.1744 | 0.1282 | 0.1459 | 0.1473 | 0.1187 | 0.1486 | 0.1054 | 0.1514 | 0.0497 | 0.2694 | 0.0028 | 0.0028 | 0.0058 | 0.0052 | 0.0106 | 0.0099 | 0.0311 | 0.0268 | 0.0659 | 0.0579 | 0.0954 | 0.0806 | 0.0809 | 0.0798 | 0.1143 | 0.1059 | 0.5934 | 0.6311 | 0.0056 | 0.0063 | 0.0141 | 0.0117 | 0.0159 | 0.0184 | 0.0286 | 0.0284 | 0.0766 | 0.0755 | 0.1048 | 0.1172 | 0.0886 | 0.0893 | 0.1172 | 0.1247 | 0.5485 | 0.5286 | 0.0026 | 0.0105 | 0.0228 | 0.0324 | 0.0762 | 0.0964 | 0.0836 | 0.1155 | 0.5599 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 816 | 393 | | 5950 | 11342 | 117.6 | 33.32 | 249.29 | 173.91 | 81 | 90 | 98 | 105 | 112 | 120 | 129 | 141 | 162 | 0.0886 | 1005 | 0.628 | 179.79 | 48.30 | 1 | 0.0987 | 587 | 0.0027 | 14.82 | 6.257 | 0.2986 | 14935.3 | 2060000 | 307000000 | 49700000000 | 0.4437 | 0.2043 | 0.0009 | 0.0002 | 0.0033 | 0.0000 | 0.0082 | 0.0002 | 0.0331 | 0.0046 | 0.0759 | 0.0228 | 0.1588 | 0.0532 | 0.1527 | 0.0566 | 0.1907 | 0.0777 | 0.3764 | 0.7848 | 0.0005 | 0.0002 | 0.0014 | 0.0000 | 0.0036 | 0.0002 | 0.0167 | 0.0016 | 0.0351 | 0.0130 | 0.0689 | 0.0288 | 0.0680 | 0.0227 | 0.0975 | 0.0363 | 0.7084 | 0.8972 | 0.0052 | 0.0056 | 0.0070 | 0.0056 | 0.0235 | 0.0206 | 0.0506 | 0.0882 | 0.0950 | 0.1689 | 0.1578 | 0.1388 | 0.1046 | 0.1107 | 0.1290 | 0.1370 | 0.4272 | 0.3246 | 0.0020 | 0.0051 | 0.0094 | 0.0279 | 0.0822 | 0.1188 | 0.0917 | 0.1200 | 0.5429 | 40 | 81 | 128 | 176 | 225 | 279 | 333 | 394 | 483 | 0.0016 | 78.48 | 7.365 | 0.2033 | 92387.6 | 42200000 | 22200000000 | 13200000000000 | 0.4848 | 0.1839 | 0.0286 | 0.0012 | 0.1297 | 0.0127 | 0.2654 | 0.0476 | 0.1826 | 0.1174 | 0.1568 | 0.1874 | 0.1170 | 0.2093 | 0.0749 | 0.1488 | 0.0314 | 0.1305 | 0.0136 | 0.1451 | 0.0005 | 0.0000 | 0.0003 | 0.0013 | 0.0040 | 0.0026 | 0.0198 | 0.0140 | 0.0727 | 0.0554 | 0.1270 | 0.1033 | 0.1058 | 0.0836 | 0.1312 | 0.1196 | 0.5388 | 0.6202 | 0.0012 | 0.0026 | 0.0065 | 0.0077 | 0.0102 | 0.0148 | 0.0349 | 0.0586 | 0.1118 | 0.1501 | 0.1780 | 0.1978 | 0.1268 | 0.1369 | 0.1581 | 0.1553 | 0.3725 | 0.2761 | 0.0002 | 0.0031 | 0.0062 | 0.0306 | 0.0849 | 0.1491 | 0.1161 | 0.1500 | 0.4598 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 162 | 234 | | 7241 | 33553 | 311.8 | 96.47 | 118.63 | 162.69 | 187 | 201 | 237 | 287 | 318 | 345 | 372 | 400 | 436 | 0.0350 | 1175 | 0.651 | 97.19 | 15.30 | 2 | 0.0305 | 221 | 0.0011 | 37.81 | 7.274 | 0.2128 | 106500.0 | 39100000 | 15200000000 | 6200000000000 | 0.4774 | 0.1776 | 0.0004 | 0.0012 | 0.0025 | 0.0024 | 0.0078 | 0.0057 | 0.0252 | 0.0134 | 0.0900 | 0.0431 | 0.1460 | 0.0745 | 0.1488 | 0.0709 | 0.1729 | 0.1150 | 0.4064 | 0.6737 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0012 | 0.0045 | 0.0020 | 0.0085 | 0.0163 | 0.0263 | 0.0285 | 0.0387 | 0.0281 | 0.0343 | 0.0386 | 0.0461 | 0.8853 | 0.8385 | 0.0024 | 0.0155 | 0.0043 | 0.0127 | 0.0119 | 0.0325 | 0.0396 | 0.0876 | 0.0835 | 0.1441 | 0.1098 | 0.1935 | 0.1150 | 0.1483 | 0.1394 | 0.1384 | 0.4940 | 0.2274 | 0.0000 | 0.0011 | 0.0029 | 0.0135 | 0.0296 | 0.0630 | 0.0643 | 0.0849 | 0.7407 | 9 | 11 | 14 | 19 | 34 | 73 | 138 | 222 | 342 | 0.1019 | 11.63 | 4.467 | 0.5909 | 40541.7 | 20200000 | 12600000000 | 9300000000000 | 0.3536 | 0.3217 | 0.0195 | 0.0035 | 0.1006 | 0.0081 | 0.1840 | 0.0477 | 0.1733 | 0.1043 | 0.1800 | 0.1722 | 0.1418 | 0.1779 | 0.1082 | 0.1344 | 0.0594 | 0.1368 | 0.0332 | 0.2151 | 0.0001 | 0.0006 | 0.0006 | 0.0005 | 0.0020 | 0.0011 | 0.0085 | 0.0076 | 0.0341 | 0.0295 | 0.0563 | 0.0485 | 0.0428 | 0.0362 | 0.0619 | 0.0541 | 0.7937 | 0.8219 | 0.0001 | 0.0002 | 0.0013 | 0.0015 | 0.0028 | 0.0035 | 0.0110 | 0.0135 | 0.0448 | 0.0478 | 0.0745 | 0.0869 | 0.0567 | 0.0645 | 0.0842 | 0.0980 | 0.7246 | 0.6843 | 0.0002 | 0.0009 | 0.0028 | 0.0099 | 0.0385 | 0.0629 | 0.0519 | 0.0705 | 0.7623 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 219 | 745 | | 5417 | 7682 | 459.9 | 105.22 | 163.49 | 154.87 | 337 | 370 | 397 | 421 | 446 | 473 | 502 | 541 | 606 | 0.1009 | 775 | 0.952 | 103.82 | 28.00 | 1 | 0.0462 | 250 | 0.0007 | 65.25 | 7.472 | 0.1512 | 222541.0 | 113000000 | 60600000000 | 34000000000000 | 0.4352 | 0.2219 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0012 | 0.0002 | 0.0160 | 0.0018 | 0.0690 | 0.0207 | 0.1406 | 0.0417 | 0.1432 | 0.0435 | 0.1788 | 0.0688 | 0.4498 | 0.8231 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0073 | 0.0006 | 0.0381 | 0.0131 | 0.0709 | 0.0252 | 0.0628 | 0.0204 | 0.0986 | 0.0385 | 0.7212 | 0.9023 | 0.0061 | 0.0059 | 0.0163 | 0.0088 | 0.0132 | 0.0147 | 0.0499 | 0.1003 | 0.0957 | 0.1504 | 0.1232 | 0.1681 | 0.0896 | 0.1386 | 0.0998 | 0.1534 | 0.5061 | 0.2596 | 0.0016 | 0.0041 | 0.0086 | 0.0345 | 0.0858 | 0.1248 | 0.0998 | 0.1281 | 0.5127 | 16 | 24 | 47 | 80 | 120 | 162 | 209 | 275 | 401 | 0.0119 | 39.04 | 6.336 | 0.3337 | 50710.0 | 20800000 | 10000000000 | 5380000000000 | 0.5608 | 0.1109 | 0.0360 | 0.0009 | 0.1274 | 0.0147 | 0.1801 | 0.0477 | 0.1670 | 0.1198 | 0.1511 | 0.1590 | 0.1292 | 0.1862 | 0.1002 | 0.1203 | 0.0712 | 0.1323 | 0.0378 | 0.2192 | 0.0008 | 0.0002 | 0.0011 | 0.0005 | 0.0016 | 0.0021 | 0.0153 | 0.0143 | 0.0629 | 0.0509 | 0.1018 | 0.0835 | 0.0862 | 0.0685 | 0.1314 | 0.1042 | 0.5988 | 0.6757 | 0.0020 | 0.0020 | 0.0016 | 0.0045 | 0.0115 | 0.0109 | 0.0262 | 0.0377 | 0.0994 | 0.0942 | 0.1224 | 0.1413 | 0.0970 | 0.0932 | 0.1431 | 0.1413 | 0.4968 | 0.4750 | 0.0000 | 0.0010 | 0.0056 | 0.0203 | 0.0811 | 0.1353 | 0.0889 | 0.1366 | 0.5312 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1211 | 933 | | 5107 | 8578 | 147.2 | 34.74 | 108.58 | 88.65 | 103 | 115 | 125 | 137 | 146 | 155 | 166 | 176 | 193 | 0.1170 | 1004 | 0.693 | 160.95 | 32.02 | 2 | 0.0770 | 393 | 0.0018 | 21.51 | 6.568 | 0.2519 | 22877.6 | 3740000 | 639000000 | 114000000000 | 0.4445 | 0.2126 | 0.0014 | 0.0000 | 0.0027 | 0.0000 | 0.0102 | 0.0013 | 0.0287 | 0.0064 | 0.0997 | 0.0227 | 0.1387 | 0.0646 | 0.1499 | 0.0612 | 0.1899 | 0.0939 | 0.3788 | 0.7501 | 0.0008 | 0.0000 | 0.0013 | 0.0000 | 0.0046 | 0.0010 | 0.0074 | 0.0038 | 0.0378 | 0.0178 | 0.0555 | 0.0427 | 0.0558 | 0.0299 | 0.0804 | 0.0465 | 0.7565 | 0.8583 | 0.0089 | 0.0213 | 0.0138 | 0.0390 | 0.0296 | 0.0496 | 0.0847 | 0.1277 | 0.1182 | 0.2163 | 0.1665 | 0.1986 | 0.1369 | 0.0957 | 0.1567 | 0.1454 | 0.2847 | 0.1064 | 0.0012 | 0.0048 | 0.0056 | 0.0306 | 0.0692 | 0.1018 | 0.1078 | 0.1301 | 0.5489 | 25 | 38 | 50 | 65 | 83 | 105 | 133 | 168 | 225 | 0.0092 | 9.19 | 5.417 | 0.4488 | 19647.3 | 5050000 | 1670000000 | 658000000000 | 0.5401 | 0.1235 | 0.0262 | 0.0039 | 0.1077 | 0.0159 | 0.2003 | 0.0478 | 0.1830 | 0.0994 | 0.1727 | 0.1452 | 0.1312 | 0.1800 | 0.0932 | 0.1462 | 0.0559 | 0.1481 | 0.0297 | 0.2135 | 0.0012 | 0.0014 | 0.0039 | 0.0039 | 0.0105 | 0.0082 | 0.0233 | 0.0227 | 0.0730 | 0.0560 | 0.1166 | 0.0957 | 0.0997 | 0.0877 | 0.1274 | 0.1094 | 0.5443 | 0.6150 | 0.0027 | 0.0059 | 0.0080 | 0.0113 | 0.0239 | 0.0231 | 0.0448 | 0.0458 | 0.0964 | 0.1241 | 0.1511 | 0.1571 | 0.1120 | 0.1108 | 0.1257 | 0.1349 | 0.4355 | 0.3870 | 0.0018 | 0.0066 | 0.0123 | 0.0361 | 0.0866 | 0.1372 | 0.1032 | 0.1351 | 0.4810 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 141 | 699 | | 7154 | 15239 | 575.9 | 95.31 | 29.74 | 48.68 | 449 | 502 | 533 | 558 | 579 | 601 | 622 | 652 | 696 | 0.0671 | 1023 | 0.931 | 90.61 | 28.60 | 3 | 0.0352 | 252 | 0.0011 | 31.86 | 7.150 | 0.2308 | 340741.0 | 207000000 | 128000000000 | 80800000000000 | 0.4150 | 0.2161 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0061 | 0.0006 | 0.0245 | 0.0127 | 0.0495 | 0.0227 | 0.0463 | 0.0142 | 0.0702 | 0.0222 | 0.8014 | 0.9276 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0025 | 0.0003 | 0.0155 | 0.0122 | 0.0287 | 0.0212 | 0.0234 | 0.0112 | 0.0340 | 0.0164 | 0.8955 | 0.9387 | 0.0066 | 0.0313 | 0.0131 | 0.1875 | 0.0210 | 0.0938 | 0.0329 | 0.1250 | 0.0631 | 0.1875 | 0.0972 | 0.1250 | 0.0907 | 0.0938 | 0.1196 | 0.1250 | 0.5558 | 0.0313 | 0.0011 | 0.0046 | 0.0060 | 0.0179 | 0.0447 | 0.0660 | 0.0690 | 0.0842 | 0.7066 | 6 | 8 | 9 | 10 | 12 | 15 | 21 | 33 | 71 | 0.1972 | 1.48 | 2.529 | 0.7147 | 3254.2 | 656547 | 165000000 | 46700000000 | 0.5056 | 0.1413 | 0.0414 | 0.0294 | 0.0670 | 0.0284 | 0.1535 | 0.0479 | 0.1859 | 0.0812 | 0.1934 | 0.1171 | 0.1618 | 0.1309 | 0.1106 | 0.1486 | 0.0640 | 0.2072 | 0.0226 | 0.2093 | 0.0062 | 0.0147 | 0.0081 | 0.0103 | 0.0180 | 0.0156 | 0.0240 | 0.0182 | 0.0531 | 0.0425 | 0.0837 | 0.0718 | 0.0721 | 0.0609 | 0.0963 | 0.1079 | 0.6385 | 0.6580 | 0.0031 | 0.0036 | 0.0076 | 0.0056 | 0.0132 | 0.0156 | 0.0287 | 0.0324 | 0.0651 | 0.0720 | 0.0970 | 0.0980 | 0.0707 | 0.0720 | 0.1050 | 0.1032 | 0.6096 | 0.5974 | 0.0052 | 0.0084 | 0.0102 | 0.0335 | 0.0664 | 0.0836 | 0.0740 | 0.0976 | 0.6210 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 343 | 266 | | 9188 | 10970 | 380.5 | 50.11 | 368.80 | 331.03 | 317 | 338 | 353 | 366 | 379 | 392 | 407 | 423 | 446 | 0.0837 | 918 | 1.098 | 128.97 | 29.02 | 1 | 0.0293 | 269 | 0.0014 | 32.93 | 6.904 | 0.2140 | 147263.0 | 58000000 | 23200000000 | 9410000000000 | 0.4808 | 0.1754 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0002 | 0.0250 | 0.0095 | 0.0514 | 0.0210 | 0.0529 | 0.0104 | 0.0987 | 0.0165 | 0.7665 | 0.9424 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0001 | 0.0138 | 0.0095 | 0.0278 | 0.0207 | 0.0261 | 0.0093 | 0.0415 | 0.0143 | 0.8895 | 0.9462 | 0.0218 | 0.0000 | 0.0328 | 0.0000 | 0.0593 | 0.0000 | 0.0874 | 0.0000 | 0.1732 | 0.0000 | 0.1841 | 0.0000 | 0.1435 | 0.0000 | 0.1388 | 0.0000 | 0.1591 | 0.0000 | 0.0011 | 0.0040 | 0.0097 | 0.0303 | 0.0725 | 0.1067 | 0.1129 | 0.1309 | 0.5320 | 26 | 44 | 103 | 182 | 274 | 391 | 529 | 679 | 850 | 0.0115 | 87.23 | 6.899 | 0.3039 | 245585.0 | 203000000 | 190000000000 | 195000000000000 | 0.5450 | 0.1332 | 0.0240 | 0.0019 | 0.1159 | 0.0052 | 0.2589 | 0.0480 | 0.1785 | 0.1152 | 0.1414 | 0.1989 | 0.1291 | 0.2063 | 0.0765 | 0.1279 | 0.0433 | 0.1290 | 0.0325 | 0.1677 | 0.0004 | 0.0003 | 0.0015 | 0.0005 | 0.0044 | 0.0031 | 0.0158 | 0.0085 | 0.0472 | 0.0440 | 0.0846 | 0.0769 | 0.0584 | 0.0516 | 0.0824 | 0.0766 | 0.7053 | 0.7384 | 0.0003 | 0.0009 | 0.0025 | 0.0032 | 0.0058 | 0.0059 | 0.0156 | 0.0215 | 0.0666 | 0.0792 | 0.1115 | 0.1340 | 0.0860 | 0.1022 | 0.1267 | 0.1240 | 0.5849 | 0.5290 | 0.0000 | 0.0026 | 0.0050 | 0.0109 | 0.0579 | 0.0934 | 0.0690 | 0.0986 | 0.6626 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 121 | 590 | | 6826 | 22797 | 692.3 | 141.16 | 184.25 | 147.65 | 524 | 569 | 603 | 636 | 672 | 711 | 754 | 812 | 894 | 0.0504 | 1149 | 1.195 | 96.01 | 36.50 | 1 | 0.0355 | 242 | 0.0006 | 74.81 | 7.679 | 0.1333 | 499160.0 | 375000000 | 293000000000 | 238000000000000 | 0.4097 | 0.2333 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0033 | 0.0000 | 0.0134 | 0.0015 | 0.0541 | 0.0141 | 0.1179 | 0.0327 | 0.1221 | 0.0242 | 0.1447 | 0.0447 | 0.5439 | 0.8825 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0001 | 0.0244 | 0.0100 | 0.0560 | 0.0208 | 0.0529 | 0.0091 | 0.0796 | 0.0171 | 0.7802 | 0.9428 | 0.0000 | 0.0210 | 0.0059 | 0.0385 | 0.0245 | 0.0559 | 0.0422 | 0.0594 | 0.1114 | 0.1713 | 0.1401 | 0.1608 | 0.1241 | 0.1014 | 0.1595 | 0.1399 | 0.3924 | 0.2517 | 0.0007 | 0.0033 | 0.0052 | 0.0244 | 0.0711 | 0.1157 | 0.0949 | 0.1252 | 0.5596 | 31 | 53 | 80 | 111 | 147 | 188 | 236 | 298 | 396 | 0.0053 | 17.90 | 6.140 | 0.3553 | 55747.2 | 22400000 | 11300000000 | 7040000000000 | 0.4802 | 0.1654 | 0.0189 | 0.0009 | 0.1045 | 0.0065 | 0.1943 | 0.0481 | 0.1712 | 0.0929 | 0.1772 | 0.1570 | 0.1568 | 0.1982 | 0.0804 | 0.1530 | 0.0592 | 0.1463 | 0.0375 | 0.1971 | 0.0006 | 0.0003 | 0.0018 | 0.0010 | 0.0062 | 0.0037 | 0.0214 | 0.0144 | 0.0636 | 0.0533 | 0.1041 | 0.0946 | 0.0826 | 0.0723 | 0.1081 | 0.1001 | 0.6117 | 0.6604 | 0.0021 | 0.0022 | 0.0055 | 0.0077 | 0.0141 | 0.0176 | 0.0366 | 0.0471 | 0.0854 | 0.0843 | 0.1155 | 0.1211 | 0.0905 | 0.0961 | 0.1101 | 0.1108 | 0.5402 | 0.5131 | 0.0011 | 0.0033 | 0.0088 | 0.0271 | 0.0757 | 0.1130 | 0.0967 | 0.1074 | 0.5670 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1119 | 214 | | 5751 | 20046 | 238.3 | 49.59 | 123.21 | 136.16 | 178 | 195 | 208 | 220 | 233 | 246 | 261 | 280 | 308 | 0.0535 | 1073 | 0.956 | 183.13 | 46.27 | 1 | 0.0753 | 433 | 0.0009 | 46.08 | 7.198 | 0.1709 | 59261.6 | 15400000 | 4150000000 | 1160000000000 | 0.4175 | 0.2356 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0005 | 0.0192 | 0.0024 | 0.0653 | 0.0160 | 0.1455 | 0.0388 | 0.1466 | 0.0377 | 0.1807 | 0.0616 | 0.4387 | 0.8430 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0005 | 0.0067 | 0.0007 | 0.0275 | 0.0110 | 0.0670 | 0.0243 | 0.0630 | 0.0150 | 0.0867 | 0.0246 | 0.7466 | 0.9238 | 0.0059 | 0.0172 | 0.0109 | 0.0515 | 0.0158 | 0.1030 | 0.0732 | 0.1373 | 0.1464 | 0.2232 | 0.1771 | 0.1588 | 0.1207 | 0.0944 | 0.1563 | 0.0987 | 0.2938 | 0.1159 | 0.0023 | 0.0026 | 0.0079 | 0.0350 | 0.0801 | 0.1287 | 0.1072 | 0.1317 | 0.5045 | 9 | 12 | 16 | 32 | 68 | 116 | 169 | 230 | 320 | 0.0565 | 15.55 | 5.256 | 0.4785 | 33719.5 | 12300000 | 5330000000 | 2640000000000 | 0.4071 | 0.2119 | 0.0276 | 0.0010 | 0.1314 | 0.0064 | 0.2324 | 0.0484 | 0.2178 | 0.1001 | 0.1708 | 0.1763 | 0.1189 | 0.2178 | 0.0605 | 0.1609 | 0.0281 | 0.1323 | 0.0124 | 0.1568 | 0.0001 | 0.0000 | 0.0005 | 0.0005 | 0.0020 | 0.0009 | 0.0121 | 0.0082 | 0.0395 | 0.0341 | 0.0660 | 0.0575 | 0.0579 | 0.0452 | 0.0777 | 0.0695 | 0.7443 | 0.7842 | 0.0004 | 0.0007 | 0.0012 | 0.0015 | 0.0041 | 0.0051 | 0.0158 | 0.0229 | 0.0539 | 0.0569 | 0.0854 | 0.0956 | 0.0750 | 0.0817 | 0.1018 | 0.1010 | 0.6624 | 0.6347 | 0.0003 | 0.0013 | 0.0027 | 0.0126 | 0.0464 | 0.0749 | 0.0671 | 0.0897 | 0.7050 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |