High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 409 | 280 | 1210 | 12705 | 136.9 | 47.47 | 7.00 | 2.25 | 94 | 99 | 105 | 113 | 125 | 135 | 147 | 166 | 194 | 0.0692 | 879 | 1.125 | 43.57 | 14.76 | 1 | 0.0917 | 111 | 0.0334 | 1.77 | 3.937 | 0.6591 | 21001.6 | 3690000 | 750000000 | 175000000000 | 0.3856 | 0.2421 | 0.0019 | 0.0000 | 0.0038 | 0.0009 | 0.0076 | 0.0037 | 0.0284 | 0.0037 | 0.0739 | 0.0435 | 0.1155 | 0.0694 | 0.1098 | 0.0527 | 0.1553 | 0.0722 | 0.5038 | 0.7539 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0039 | 0.0017 | 0.0116 | 0.0033 | 0.0374 | 0.0315 | 0.0452 | 0.0497 | 0.0477 | 0.0339 | 0.0671 | 0.0464 | 0.7845 | 0.8336 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0157 | 0.0202 | 0.0315 | 0.0769 | 0.0945 | 0.1012 | 0.0945 | 0.0526 | 0.0945 | 0.1053 | 0.1102 | 0.6397 | 0.5591 | 0.0000 | 0.0021 | 0.0021 | 0.0170 | 0.0574 | 0.0894 | 0.0553 | 0.0830 | 0.6936 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.1326 | 0.46 | 0.972 | 0.3927 | 54.0 | 451.734 | 4043.45 | 38474.4 | 0.5298 | 0.1304 | 0.0062 | 0.0002 | 0.0387 | 0.0032 | 0.1097 | 0.0167 | 0.2018 | 0.0466 | 0.2471 | 0.1144 | 0.2141 | 0.2065 | 0.1330 | 0.2787 | 0.0443 | 0.2384 | 0.0050 | 0.0952 | 0.0003 | 0.0001 | 0.0037 | 0.0005 | 0.0155 | 0.0037 | 0.0453 | 0.0137 | 0.0937 | 0.0398 | 0.1649 | 0.1009 | 0.2199 | 0.1973 | 0.2501 | 0.3137 | 0.2066 | 0.3304 | 0.1155 | 0.2819 | 0.2058 | 0.2713 | 0.2077 | 0.1960 | 0.1816 | 0.1282 | 0.1344 | 0.0765 | 0.0859 | 0.0348 | 0.0478 | 0.0106 | 0.0186 | 0.0006 | 0.0028 | 0.0000 | 0.0087 | 0.0317 | 0.0841 | 0.1455 | 0.1982 | 0.2028 | 0.1646 | 0.1124 | 0.0521 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 373 | 297 | 8100 | 26881 | 413.8 | 80.21 | 134.66 | 112.18 | 311 | 343 | 368 | 389 | 410 | 432 | 457 | 483 | 520 | 0.0428 | 1150 | 1.063 | 121.84 | 35.38 | 1 | 0.0363 | 294 | 0.0012 | 29.87 | 6.930 | 0.2112 | 177657.0 | 78900000 | 36200000000 | 17100000000000 | 0.4441 | 0.2061 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0031 | 0.0001 | 0.0127 | 0.0006 | 0.0529 | 0.0119 | 0.1206 | 0.0278 | 0.1395 | 0.0227 | 0.1558 | 0.0414 | 0.5151 | 0.8954 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0005 | 0.0215 | 0.0096 | 0.0486 | 0.0211 | 0.0558 | 0.0122 | 0.0700 | 0.0216 | 0.7987 | 0.9350 | 0.0038 | 0.0471 | 0.0045 | 0.0059 | 0.0257 | 0.0941 | 0.0863 | 0.1588 | 0.1529 | 0.1412 | 0.2044 | 0.2118 | 0.1317 | 0.0647 | 0.1363 | 0.0706 | 0.2544 | 0.2059 | 0.0005 | 0.0013 | 0.0066 | 0.0247 | 0.0683 | 0.1268 | 0.1056 | 0.1298 | 0.5363 | 27 | 46 | 66 | 85 | 107 | 130 | 159 | 200 | 272 | 0.0091 | 10.68 | 5.490 | 0.4380 | 30717.4 | 10300000 | 4530000000 | 2410000000000 | 0.4651 | 0.1879 | 0.0107 | 0.0010 | 0.0569 | 0.0033 | 0.1502 | 0.0207 | 0.1620 | 0.0586 | 0.1808 | 0.1345 | 0.1705 | 0.1748 | 0.1171 | 0.1516 | 0.0871 | 0.1645 | 0.0646 | 0.2909 | 0.0008 | 0.0005 | 0.0020 | 0.0009 | 0.0061 | 0.0038 | 0.0179 | 0.0117 | 0.0589 | 0.0446 | 0.1034 | 0.0774 | 0.0837 | 0.0680 | 0.1176 | 0.1006 | 0.6097 | 0.6925 | 0.0016 | 0.0022 | 0.0055 | 0.0050 | 0.0095 | 0.0162 | 0.0356 | 0.0429 | 0.0832 | 0.1003 | 0.1356 | 0.1457 | 0.1111 | 0.1195 | 0.1349 | 0.1425 | 0.4830 | 0.4257 | 0.0007 | 0.0045 | 0.0076 | 0.0250 | 0.0755 | 0.1170 | 0.0983 | 0.1280 | 0.5435 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 77 | 299 | 362 | 804 | 84.7 | 13.26 | 9.06 | 3.12 | 65 | 72 | 78 | 84 | 87 | 90 | 93 | 96 | 100 | 0.2786 | 224 | 0.728 | 31.40 | 8.49 | 1 | 0.2459 | 89 | 0.0508 | 1.25 | 3.272 | 0.6191 | 7352.5 | 651714 | 58800000 | 5400000000 | 0.3674 | 0.2592 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0351 | 0.0028 | 0.0596 | 0.0442 | 0.1053 | 0.0912 | 0.1368 | 0.0276 | 0.1825 | 0.0608 | 0.4737 | 0.7735 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0000 | 0.0256 | 0.0028 | 0.0415 | 0.0442 | 0.0607 | 0.0912 | 0.0607 | 0.0276 | 0.0799 | 0.0608 | 0.7252 | 0.7735 | 0.0714 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.1429 | 0.0000 | 0.2143 | 0.0000 | 0.1786 | 0.0000 | 0.0357 | 0.0000 | 0.1071 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0242 | 0.0338 | 0.0725 | 0.0725 | 0.0966 | 0.1401 | 0.5556 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 0.0140 | 20.20 | 4.617 | 0.2555 | 91.8 | 1010.84 | 11937.1 | 150060 | 0.5369 | 0.1144 | 0.0442 | 0.0017 | 0.1633 | 0.0034 | 0.2449 | 0.0458 | 0.2415 | 0.1171 | 0.1565 | 0.1460 | 0.0884 | 0.2530 | 0.0476 | 0.2054 | 0.0102 | 0.1562 | 0.0034 | 0.0713 | 0.0018 | 0.0000 | 0.0235 | 0.0000 | 0.0470 | 0.0056 | 0.1302 | 0.0405 | 0.2061 | 0.1103 | 0.2188 | 0.1494 | 0.2116 | 0.1955 | 0.1157 | 0.2598 | 0.0452 | 0.2388 | 0.1042 | 0.3150 | 0.2008 | 0.3858 | 0.2124 | 0.2283 | 0.2432 | 0.0394 | 0.1236 | 0.0315 | 0.0811 | 0.0000 | 0.0270 | 0.0000 | 0.0077 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0424 | 0.1038 | 0.2076 | 0.2182 | 0.1801 | 0.1547 | 0.0657 | 0.0233 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | |||
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 640 | 505 | 7321 | 15664 | 132.9 | 24.36 | 203.28 | 114.00 | 103 | 113 | 120 | 126 | 131 | 137 | 144 | 152 | 164 | 0.0602 | 943 | 0.886 | 94.20 | 24.52 | 1 | 0.0328 | 240 | 0.0034 | 11.56 | 6.014 | 0.3124 | 18256.5 | 2590000 | 379000000 | 57200000000 | 0.4249 | 0.2269 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0031 | 0.0001 | 0.0107 | 0.0008 | 0.0451 | 0.0126 | 0.0959 | 0.0291 | 0.1106 | 0.0302 | 0.1519 | 0.0455 | 0.5827 | 0.8815 | 0.0000 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0006 | 0.0213 | 0.0113 | 0.0421 | 0.0206 | 0.0458 | 0.0151 | 0.0696 | 0.0214 | 0.8160 | 0.9308 | 0.0083 | 0.0311 | 0.0156 | 0.0497 | 0.0353 | 0.0807 | 0.1048 | 0.1491 | 0.1566 | 0.2609 | 0.1940 | 0.1677 | 0.1193 | 0.0621 | 0.1421 | 0.1429 | 0.2241 | 0.0559 | 0.0026 | 0.0048 | 0.0145 | 0.0318 | 0.0705 | 0.1166 | 0.1066 | 0.1362 | 0.5163 | 66 | 100 | 130 | 159 | 188 | 221 | 256 | 298 | 361 | 0.0013 | 36.57 | 7.039 | 0.2500 | 54319.8 | 17300000 | 6280000000 | 2520000000000 | 0.5417 | 0.1374 | 0.0116 | 0.0006 | 0.0610 | 0.0034 | 0.1692 | 0.0206 | 0.1815 | 0.0547 | 0.2027 | 0.1259 | 0.1727 | 0.1917 | 0.1056 | 0.1593 | 0.0625 | 0.1770 | 0.0330 | 0.2666 | 0.0005 | 0.0002 | 0.0016 | 0.0004 | 0.0064 | 0.0030 | 0.0191 | 0.0101 | 0.0584 | 0.0425 | 0.1194 | 0.0871 | 0.0931 | 0.0697 | 0.1203 | 0.1000 | 0.5810 | 0.6870 | 0.0025 | 0.0036 | 0.0078 | 0.0101 | 0.0228 | 0.0258 | 0.0457 | 0.0697 | 0.1071 | 0.1403 | 0.1660 | 0.1930 | 0.1333 | 0.1409 | 0.1465 | 0.1479 | 0.3682 | 0.2686 | 0.0013 | 0.0039 | 0.0104 | 0.0303 | 0.0787 | 0.1477 | 0.1131 | 0.1412 | 0.4735 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1026 | 526 | 1774 | 10377 | 333.7 | 82.77 | 7.07 | 6.95 | 228 | 252 | 275 | 299 | 328 | 356 | 381 | 404 | 456 | 0.0754 | 782 | 1.019 | 63.03 | 17.72 | 1 | 0.0902 | 160 | 0.0074 | 2.20 | 5.116 | 0.5219 | 118176.0 | 44200000 | 17400000000 | 7100000000000 | 0.3704 | 0.2523 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0044 | 0.0018 | 0.0196 | 0.0031 | 0.0480 | 0.0270 | 0.0981 | 0.0590 | 0.0960 | 0.0277 | 0.1156 | 0.0522 | 0.6161 | 0.8291 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0006 | 0.0077 | 0.0006 | 0.0216 | 0.0198 | 0.0448 | 0.0475 | 0.0309 | 0.0158 | 0.0394 | 0.0300 | 0.8533 | 0.8858 | 0.0000 | 0.0070 | 0.0026 | 0.0000 | 0.0159 | 0.0211 | 0.0265 | 0.0493 | 0.0688 | 0.0563 | 0.0688 | 0.0634 | 0.0794 | 0.1197 | 0.0926 | 0.1127 | 0.6455 | 0.5704 | 0.0000 | 0.0012 | 0.0035 | 0.0106 | 0.0307 | 0.0507 | 0.0460 | 0.0507 | 0.8066 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.0683 | 0.36 | 0.960 | 0.2803 | 98.4 | 3645.61 | 211535 | 13700000 | 0.5870 | 0.1077 | 0.0219 | 0.0000 | 0.0918 | 0.0034 | 0.2036 | 0.0218 | 0.2478 | 0.0615 | 0.2315 | 0.1441 | 0.1344 | 0.2346 | 0.0524 | 0.2632 | 0.0151 | 0.1992 | 0.0014 | 0.0723 | 0.0070 | 0.0001 | 0.0372 | 0.0017 | 0.1009 | 0.0115 | 0.1433 | 0.0351 | 0.1866 | 0.1006 | 0.1797 | 0.1701 | 0.1357 | 0.2256 | 0.0991 | 0.2326 | 0.1105 | 0.2226 | 0.2165 | 0.2377 | 0.1957 | 0.1575 | 0.1447 | 0.1137 | 0.0919 | 0.0699 | 0.0705 | 0.0657 | 0.0566 | 0.0428 | 0.0334 | 0.0323 | 0.0340 | 0.0396 | 0.1567 | 0.2409 | 0.0252 | 0.0972 | 0.1538 | 0.1674 | 0.1709 | 0.1299 | 0.1019 | 0.0664 | 0.0874 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 710 | 620 | 2360 | 11953 | 110.5 | 24.96 | 211.01 | 181.60 | 79 | 90 | 97 | 103 | 109 | 115 | 122 | 130 | 142 | 0.0590 | 705 | 0.447 | 155.82 | 21.02 | 1 | 0.1462 | 345 | 0.0035 | 13.00 | 5.933 | 0.3106 | 12827.3 | 1560000 | 199000000 | 26300000000 | 0.4832 | 0.1861 | 0.0020 | 0.0000 | 0.0067 | 0.0009 | 0.0153 | 0.0032 | 0.0313 | 0.0074 | 0.0825 | 0.0300 | 0.1297 | 0.0669 | 0.1457 | 0.0646 | 0.1816 | 0.0817 | 0.4052 | 0.7453 | 0.0000 | 0.0000 | 0.0021 | 0.0004 | 0.0046 | 0.0022 | 0.0108 | 0.0043 | 0.0344 | 0.0195 | 0.0729 | 0.0468 | 0.0667 | 0.0299 | 0.0959 | 0.0468 | 0.7127 | 0.8501 | 0.0135 | 0.0000 | 0.0202 | 0.0142 | 0.0314 | 0.0638 | 0.0695 | 0.1702 | 0.1457 | 0.2766 | 0.1570 | 0.2057 | 0.1771 | 0.1135 | 0.1592 | 0.0922 | 0.2265 | 0.0638 | 0.0026 | 0.0026 | 0.0105 | 0.0438 | 0.0771 | 0.1402 | 0.1174 | 0.1446 | 0.4610 | 19 | 35 | 72 | 116 | 165 | 219 | 291 | 373 | 476 | 0.0088 | 40.77 | 6.716 | 0.3192 | 77499.7 | 35900000 | 19100000000 | 11300000000000 | 0.4707 | 0.1858 | 0.0171 | 0.0021 | 0.0769 | 0.0036 | 0.2135 | 0.0261 | 0.1532 | 0.0751 | 0.1780 | 0.1641 | 0.1449 | 0.2033 | 0.1100 | 0.1570 | 0.0651 | 0.1501 | 0.0414 | 0.2187 | 0.0003 | 0.0006 | 0.0014 | 0.0012 | 0.0042 | 0.0020 | 0.0115 | 0.0070 | 0.0431 | 0.0341 | 0.0776 | 0.0678 | 0.0739 | 0.0548 | 0.0927 | 0.0836 | 0.6952 | 0.7490 | 0.0010 | 0.0009 | 0.0021 | 0.0014 | 0.0067 | 0.0080 | 0.0200 | 0.0233 | 0.0562 | 0.0639 | 0.0998 | 0.1198 | 0.0814 | 0.0974 | 0.1131 | 0.1263 | 0.6197 | 0.5591 | 0.0002 | 0.0010 | 0.0051 | 0.0156 | 0.0562 | 0.0902 | 0.0770 | 0.0984 | 0.6564 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1057 | 334 | 2802 | 7296 | 92.2 | 25.90 | 117.02 | 76.72 | 61 | 72 | 78 | 83 | 89 | 94 | 102 | 114 | 128 | 0.0968 | 706 | 0.875 | 120.79 | 34.99 | 2 | 0.1071 | 300 | 0.0040 | 10.09 | 5.865 | 0.3358 | 9174.8 | 979929 | 112000000 | 13500000000 | 0.4595 | 0.1918 | 0.0026 | 0.0000 | 0.0019 | 0.0000 | 0.0136 | 0.0034 | 0.0285 | 0.0107 | 0.0783 | 0.0390 | 0.1462 | 0.0642 | 0.1481 | 0.0723 | 0.1708 | 0.0985 | 0.4101 | 0.7119 | 0.0005 | 0.0000 | 0.0009 | 0.0000 | 0.0055 | 0.0027 | 0.0110 | 0.0050 | 0.0375 | 0.0249 | 0.0536 | 0.0345 | 0.0659 | 0.0383 | 0.0893 | 0.0509 | 0.7358 | 0.8437 | 0.0031 | 0.0036 | 0.0047 | 0.0182 | 0.0219 | 0.0400 | 0.0470 | 0.0800 | 0.0799 | 0.1091 | 0.1270 | 0.1564 | 0.0831 | 0.1273 | 0.1191 | 0.1309 | 0.5141 | 0.3345 | 0.0057 | 0.0123 | 0.0188 | 0.0286 | 0.0645 | 0.0989 | 0.0784 | 0.1078 | 0.5850 | 35 | 49 | 64 | 82 | 101 | 122 | 146 | 178 | 225 | 0.0071 | 10.21 | 5.520 | 0.4012 | 19579.1 | 4150000 | 1040000000 | 297000000000 | 0.5233 | 0.1494 | 0.0087 | 0.0019 | 0.0570 | 0.0036 | 0.1531 | 0.0185 | 0.1866 | 0.0588 | 0.2102 | 0.1426 | 0.1618 | 0.1929 | 0.1054 | 0.1643 | 0.0688 | 0.1647 | 0.0484 | 0.2527 | 0.0015 | 0.0006 | 0.0028 | 0.0017 | 0.0081 | 0.0062 | 0.0233 | 0.0159 | 0.0535 | 0.0453 | 0.0933 | 0.0805 | 0.0813 | 0.0620 | 0.1102 | 0.0836 | 0.6260 | 0.7042 | 0.0013 | 0.0023 | 0.0047 | 0.0085 | 0.0214 | 0.0194 | 0.0343 | 0.0461 | 0.0909 | 0.1071 | 0.1496 | 0.1720 | 0.1127 | 0.1236 | 0.1444 | 0.1384 | 0.4406 | 0.3827 | 0.0026 | 0.0058 | 0.0125 | 0.0295 | 0.0655 | 0.1210 | 0.1079 | 0.1339 | 0.5213 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 271 | 234 | 4849 | 8509 | 138.5 | 37.61 | 168.08 | 116.27 | 97 | 108 | 116 | 125 | 133 | 143 | 153 | 166 | 185 | 0.0903 | 768 | 0.853 | 97.87 | 27.20 | 1 | 0.0524 | 254 | 0.0019 | 23.69 | 6.561 | 0.2428 | 20609.1 | 3310000 | 576000000 | 109000000000 | 0.4479 | 0.1970 | 0.0011 | 0.0000 | 0.0041 | 0.0000 | 0.0103 | 0.0007 | 0.0347 | 0.0030 | 0.0975 | 0.0240 | 0.1680 | 0.0552 | 0.1473 | 0.0550 | 0.1743 | 0.0965 | 0.3626 | 0.7657 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0030 | 0.0000 | 0.0123 | 0.0013 | 0.0355 | 0.0161 | 0.0695 | 0.0309 | 0.0711 | 0.0237 | 0.0993 | 0.0428 | 0.7066 | 0.8852 | 0.0042 | 0.0206 | 0.0084 | 0.0413 | 0.0190 | 0.0324 | 0.0685 | 0.1150 | 0.1496 | 0.1711 | 0.1707 | 0.1917 | 0.1201 | 0.1003 | 0.1465 | 0.0944 | 0.3130 | 0.2330 | 0.0009 | 0.0047 | 0.0117 | 0.0314 | 0.0835 | 0.1234 | 0.1183 | 0.1427 | 0.4833 | 38 | 66 | 89 | 113 | 143 | 180 | 216 | 263 | 330 | 0.0018 | 46.51 | 6.975 | 0.2588 | 41766.1 | 13000000 | 4740000000 | 1930000000000 | 0.4999 | 0.1620 | 0.0124 | 0.0018 | 0.0599 | 0.0036 | 0.1785 | 0.0173 | 0.2094 | 0.0574 | 0.1872 | 0.1344 | 0.1408 | 0.2044 | 0.0982 | 0.1652 | 0.0624 | 0.1709 | 0.0513 | 0.2450 | 0.0000 | 0.0005 | 0.0009 | 0.0009 | 0.0025 | 0.0038 | 0.0156 | 0.0096 | 0.0467 | 0.0356 | 0.0847 | 0.0597 | 0.0774 | 0.0637 | 0.1241 | 0.0957 | 0.6481 | 0.7305 | 0.0014 | 0.0023 | 0.0028 | 0.0064 | 0.0084 | 0.0138 | 0.0298 | 0.0527 | 0.0922 | 0.1087 | 0.1388 | 0.1577 | 0.1247 | 0.1220 | 0.1496 | 0.1298 | 0.4523 | 0.4067 | 0.0000 | 0.0008 | 0.0024 | 0.0176 | 0.0680 | 0.1114 | 0.0973 | 0.1403 | 0.5622 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 317 | 690 | 3464 | 11834 | 342.0 | 75.63 | 178.33 | 204.51 | 250 | 275 | 296 | 316 | 334 | 353 | 374 | 407 | 449 | 0.0724 | 857 | 0.954 | 122.41 | 43.14 | 1 | 0.0944 | 327 | 0.0010 | 39.91 | 7.112 | 0.1793 | 122696.0 | 46100000 | 18100000000 | 7380000000000 | 0.3949 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0033 | 0.0000 | 0.0135 | 0.0025 | 0.0652 | 0.0246 | 0.1226 | 0.0467 | 0.1086 | 0.0418 | 0.1407 | 0.0563 | 0.5461 | 0.8278 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0061 | 0.0015 | 0.0275 | 0.0178 | 0.0582 | 0.0338 | 0.0453 | 0.0228 | 0.0735 | 0.0336 | 0.7874 | 0.8906 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0061 | 0.0000 | 0.0350 | 0.0000 | 0.1035 | 0.0000 | 0.1461 | 0.0000 | 0.0989 | 0.0000 | 0.1370 | 0.0000 | 0.4718 | 0.0000 | 0.0006 | 0.0025 | 0.0063 | 0.0151 | 0.0753 | 0.0834 | 0.0997 | 0.1173 | 0.5997 | 15 | 19 | 31 | 55 | 87 | 145 | 230 | 323 | 470 | 0.0227 | 19.50 | 5.564 | 0.4886 | 73621.5 | 41900000 | 28500000000 | 21900000000000 | 0.6117 | 0.0866 | 0.0329 | 0.0009 | 0.1078 | 0.0038 | 0.2187 | 0.0509 | 0.1920 | 0.0937 | 0.1694 | 0.1715 | 0.1283 | 0.2068 | 0.0688 | 0.1413 | 0.0431 | 0.1328 | 0.0390 | 0.1983 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0009 | 0.0090 | 0.0061 | 0.0363 | 0.0348 | 0.0722 | 0.0563 | 0.0539 | 0.0445 | 0.0705 | 0.0661 | 0.7557 | 0.7909 | 0.0003 | 0.0006 | 0.0018 | 0.0012 | 0.0021 | 0.0033 | 0.0127 | 0.0169 | 0.0496 | 0.0586 | 0.0939 | 0.1112 | 0.0702 | 0.0843 | 0.0915 | 0.0991 | 0.6779 | 0.6248 | 0.0000 | 0.0007 | 0.0017 | 0.0106 | 0.0439 | 0.0866 | 0.0599 | 0.0792 | 0.7175 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 331 | 718 | 6517 | 14109 | 121.3 | 38.02 | 212.08 | 139.30 | 76 | 89 | 98 | 106 | 116 | 126 | 139 | 154 | 173 | 0.0670 | 946 | 0.522 | 141.32 | 34.66 | 1 | 0.0758 | 494 | 0.0017 | 23.72 | 6.654 | 0.2362 | 16163.3 | 2350000 | 371000000 | 63300000000 | 0.4672 | 0.1926 | 0.0013 | 0.0002 | 0.0033 | 0.0000 | 0.0140 | 0.0028 | 0.0447 | 0.0100 | 0.1142 | 0.0351 | 0.1883 | 0.0820 | 0.1596 | 0.0767 | 0.1756 | 0.1199 | 0.2990 | 0.6732 | 0.0004 | 0.0002 | 0.0017 | 0.0000 | 0.0041 | 0.0012 | 0.0137 | 0.0047 | 0.0345 | 0.0203 | 0.0687 | 0.0391 | 0.0668 | 0.0281 | 0.0852 | 0.0555 | 0.7248 | 0.8511 | 0.0006 | 0.0027 | 0.0019 | 0.0190 | 0.0131 | 0.0244 | 0.0473 | 0.0799 | 0.1021 | 0.1721 | 0.1594 | 0.2033 | 0.1152 | 0.1179 | 0.1519 | 0.1518 | 0.4085 | 0.2290 | 0.0014 | 0.0024 | 0.0106 | 0.0294 | 0.0608 | 0.1086 | 0.0820 | 0.1134 | 0.5914 | 42 | 83 | 121 | 156 | 193 | 231 | 273 | 329 | 409 | 0.0025 | 30.32 | 6.672 | 0.2808 | 64379.2 | 23700000 | 9980000000 | 4630000000000 | 0.5768 | 0.1249 | 0.0132 | 0.0007 | 0.0829 | 0.0038 | 0.2244 | 0.0304 | 0.2064 | 0.0794 | 0.1855 | 0.1514 | 0.1565 | 0.2137 | 0.0868 | 0.1808 | 0.0344 | 0.1635 | 0.0100 | 0.1763 | 0.0005 | 0.0000 | 0.0010 | 0.0005 | 0.0062 | 0.0022 | 0.0221 | 0.0124 | 0.0612 | 0.0460 | 0.1242 | 0.0904 | 0.0972 | 0.0798 | 0.1246 | 0.1106 | 0.5630 | 0.6581 | 0.0029 | 0.0020 | 0.0062 | 0.0061 | 0.0179 | 0.0276 | 0.0458 | 0.0711 | 0.1142 | 0.1294 | 0.1552 | 0.1673 | 0.1257 | 0.1207 | 0.1490 | 0.1595 | 0.3830 | 0.3164 | 0.0008 | 0.0041 | 0.0099 | 0.0341 | 0.0887 | 0.1328 | 0.1162 | 0.1460 | 0.4674 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1098 | 160 | 13724 | 21102 | 109.6 | 32.03 | 139.67 | 113.32 | 75 | 84 | 91 | 97 | 104 | 112 | 121 | 133 | 152 | 0.0598 | 1262 | 0.543 | 155.77 | 38.28 | 1 | 0.0358 | 491 | 0.0012 | 36.99 | 7.099 | 0.2067 | 13040.5 | 1690000 | 237000000 | 36400000000 | 0.4757 | 0.1867 | 0.0010 | 0.0001 | 0.0041 | 0.0003 | 0.0130 | 0.0016 | 0.0426 | 0.0043 | 0.0995 | 0.0236 | 0.1665 | 0.0560 | 0.1630 | 0.0574 | 0.1878 | 0.0954 | 0.3226 | 0.7614 | 0.0005 | 0.0001 | 0.0013 | 0.0001 | 0.0034 | 0.0002 | 0.0125 | 0.0008 | 0.0402 | 0.0130 | 0.0734 | 0.0252 | 0.0716 | 0.0218 | 0.1009 | 0.0456 | 0.6963 | 0.8934 | 0.0044 | 0.0054 | 0.0078 | 0.0168 | 0.0271 | 0.0337 | 0.0640 | 0.0804 | 0.1118 | 0.1692 | 0.1406 | 0.1937 | 0.1349 | 0.1026 | 0.1386 | 0.1394 | 0.3707 | 0.2588 | 0.0024 | 0.0058 | 0.0129 | 0.0351 | 0.0814 | 0.1154 | 0.0950 | 0.1140 | 0.5380 | 25 | 40 | 60 | 83 | 110 | 142 | 177 | 222 | 298 | 0.0094 | 10.78 | 5.597 | 0.4544 | 32349.4 | 10000000 | 3730000000 | 1590000000000 | 0.5105 | 0.1695 | 0.0131 | 0.0019 | 0.0728 | 0.0040 | 0.1644 | 0.0224 | 0.1683 | 0.0713 | 0.1736 | 0.1476 | 0.1439 | 0.1890 | 0.1111 | 0.1477 | 0.0831 | 0.1506 | 0.0697 | 0.2653 | 0.0009 | 0.0007 | 0.0013 | 0.0014 | 0.0035 | 0.0034 | 0.0133 | 0.0126 | 0.0502 | 0.0386 | 0.0839 | 0.0657 | 0.0680 | 0.0578 | 0.1044 | 0.0854 | 0.6745 | 0.7344 | 0.0012 | 0.0013 | 0.0045 | 0.0041 | 0.0086 | 0.0141 | 0.0281 | 0.0380 | 0.0821 | 0.1031 | 0.1290 | 0.1509 | 0.1030 | 0.1107 | 0.1319 | 0.1375 | 0.5116 | 0.4403 | 0.0013 | 0.0019 | 0.0052 | 0.0196 | 0.0680 | 0.1022 | 0.0904 | 0.1250 | 0.5864 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 607 | 650 | 808 | 9723 | 822.7 | 285.42 | 10.47 | 10.85 | 493 | 549 | 610 | 675 | 765 | 856 | 972 | 1125 | 1261 | 0.0725 | 705 | 0.565 | 32.65 | 5.00 | 1 | 0.1114 | 90 | 0.0018 | 33.14 | 6.417 | 0.1590 | 758238.0 | 769000000 | 841000000000 | 970000000000000 | 0.3548 | 0.2711 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0038 | 0.0017 | 0.1057 | 0.0517 | 0.2453 | 0.1138 | 0.1057 | 0.0552 | 0.1811 | 0.0845 | 0.3585 | 0.6931 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0400 | 0.0332 | 0.0700 | 0.0622 | 0.0280 | 0.0249 | 0.0600 | 0.0443 | 0.8000 | 0.8340 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0681 | 0.0839 | 0.1021 | 0.1259 | 0.0340 | 0.0420 | 0.0681 | 0.0909 | 0.7277 | 0.6504 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0538 | 0.0595 | 0.0482 | 0.0680 | 0.7620 | 5 | 6 | 6 | 7 | 8 | 8 | 9 | 11 | 17 | 0.1294 | 0.43 | 1.360 | 0.4878 | 227.2 | 11518.1 | 951002 | 99400000 | 0.4627 | 0.1724 | 0.0445 | 0.0009 | 0.1116 | 0.0040 | 0.1533 | 0.0184 | 0.1904 | 0.0460 | 0.1793 | 0.1011 | 0.1539 | 0.1744 | 0.0974 | 0.2117 | 0.0526 | 0.2479 | 0.0170 | 0.1955 | 0.0262 | 0.0002 | 0.0614 | 0.0026 | 0.0785 | 0.0118 | 0.0849 | 0.0295 | 0.0861 | 0.0688 | 0.0922 | 0.1203 | 0.0968 | 0.1483 | 0.1240 | 0.1897 | 0.3498 | 0.4287 | 0.0345 | 0.0237 | 0.0367 | 0.0266 | 0.0434 | 0.0180 | 0.0579 | 0.0633 | 0.0880 | 0.0957 | 0.1030 | 0.1165 | 0.0935 | 0.1043 | 0.1253 | 0.1288 | 0.4176 | 0.4230 | 0.0560 | 0.0567 | 0.0599 | 0.0685 | 0.0868 | 0.0890 | 0.1015 | 0.1209 | 0.3606 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 764 | 823 | 6160 | 9088 | 204.9 | 44.54 | 210.61 | 171.66 | 152 | 168 | 179 | 190 | 200 | 211 | 223 | 239 | 264 | 0.0980 | 891 | 1.013 | 96.21 | 25.02 | 1 | 0.0381 | 235 | 0.0012 | 43.96 | 7.040 | 0.1905 | 43952.7 | 9880000 | 2330000000 | 576000000000 | 0.4516 | 0.2009 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0159 | 0.0009 | 0.0737 | 0.0187 | 0.1409 | 0.0415 | 0.1416 | 0.0468 | 0.1792 | 0.0731 | 0.4452 | 0.8191 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0049 | 0.0002 | 0.0318 | 0.0125 | 0.0631 | 0.0233 | 0.0618 | 0.0189 | 0.0953 | 0.0339 | 0.7420 | 0.9113 | 0.0039 | 0.0160 | 0.0106 | 0.0543 | 0.0299 | 0.0607 | 0.0781 | 0.1182 | 0.1408 | 0.1725 | 0.2064 | 0.2013 | 0.1225 | 0.1182 | 0.1524 | 0.1054 | 0.2555 | 0.1534 | 0.0025 | 0.0032 | 0.0104 | 0.0365 | 0.0879 | 0.1397 | 0.1065 | 0.1415 | 0.4718 | 39 | 68 | 97 | 128 | 165 | 210 | 263 | 332 | 440 | 0.0016 | 92.09 | 7.254 | 0.2167 | 73819.8 | 36000000 | 22600000000 | 17500000000000 | 0.5552 | 0.1172 | 0.0288 | 0.0009 | 0.1403 | 0.0040 | 0.2442 | 0.0581 | 0.1735 | 0.1210 | 0.1653 | 0.1922 | 0.1083 | 0.2065 | 0.0802 | 0.1390 | 0.0401 | 0.1287 | 0.0194 | 0.1496 | 0.0002 | 0.0002 | 0.0018 | 0.0009 | 0.0043 | 0.0038 | 0.0235 | 0.0144 | 0.0801 | 0.0642 | 0.1300 | 0.1163 | 0.1023 | 0.0810 | 0.1381 | 0.1164 | 0.5198 | 0.6028 | 0.0014 | 0.0031 | 0.0038 | 0.0031 | 0.0153 | 0.0206 | 0.0400 | 0.0601 | 0.1247 | 0.1250 | 0.1626 | 0.1737 | 0.1107 | 0.1123 | 0.1393 | 0.1368 | 0.4022 | 0.3654 | 0.0003 | 0.0006 | 0.0075 | 0.0304 | 0.1033 | 0.1536 | 0.1133 | 0.1467 | 0.4445 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 305 | 577 | 1224 | 107.4 | 19.71 | 5.63 | 1.94 | 82 | 89 | 96 | 101 | 108 | 113 | 118 | 125 | 133 | 0.2230 | 273 | 1.197 | 35.36 | 14.21 | 1 | 0.1664 | 96 | 0.0277 | 1.58 | 3.824 | 0.5880 | 11913.2 | 1360000 | 161000000 | 19400000000 | 0.3940 | 0.2372 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0051 | 0.0000 | 0.0304 | 0.0018 | 0.0658 | 0.0406 | 0.1392 | 0.0689 | 0.1342 | 0.0548 | 0.1519 | 0.0707 | 0.4709 | 0.7633 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0000 | 0.0000 | 0.0143 | 0.0017 | 0.0369 | 0.0399 | 0.0656 | 0.0624 | 0.0615 | 0.0295 | 0.0820 | 0.0503 | 0.7377 | 0.8163 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0968 | 0.6364 | 0.1290 | 0.1818 | 0.2796 | 0.0909 | 0.1075 | 0.0909 | 0.1398 | 0.0000 | 0.2473 | 0.0000 | 0.0034 | 0.0068 | 0.0169 | 0.0203 | 0.0811 | 0.0980 | 0.0743 | 0.0845 | 0.6149 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0263 | 7.62 | 3.939 | 0.3680 | 35.5 | 244.168 | 1810.28 | 14316.1 | 0.5714 | 0.1153 | 0.0047 | 0.0000 | 0.0712 | 0.0040 | 0.1377 | 0.0160 | 0.2389 | 0.0419 | 0.2358 | 0.1028 | 0.2294 | 0.1766 | 0.0585 | 0.2535 | 0.0190 | 0.2685 | 0.0047 | 0.1367 | 0.0000 | 0.0000 | 0.0154 | 0.0019 | 0.0475 | 0.0065 | 0.1342 | 0.0260 | 0.1853 | 0.0854 | 0.2601 | 0.1365 | 0.1936 | 0.2201 | 0.1211 | 0.2934 | 0.0428 | 0.2303 | 0.3190 | 0.5467 | 0.3667 | 0.3333 | 0.1571 | 0.1067 | 0.1238 | 0.0133 | 0.0286 | 0.0000 | 0.0048 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0280 | 0.1226 | 0.1559 | 0.1961 | 0.2259 | 0.1471 | 0.0753 | 0.0350 | 0.0140 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 395 | 909 | 589 | 5786 | 12.0 | 2.37 | 6.24 | 2.23 | 9 | 10 | 11 | 11 | 12 | 12 | 13 | 14 | 15 | 0.0990 | 573 | 0.731 | 73.43 | 17.00 | 0 | 0.3192 | 188 | 0.0185 | 6.32 | 4.289 | 0.3960 | 150.6 | 1953.66 | 26252.6 | 364792 | 0.3695 | 0.2656 | 0.0046 | 0.0000 | 0.0069 | 0.0018 | 0.0324 | 0.0036 | 0.0694 | 0.0164 | 0.1019 | 0.0455 | 0.1343 | 0.0764 | 0.1898 | 0.1218 | 0.1736 | 0.1818 | 0.2870 | 0.5527 | 0.0000 | 0.0000 | 0.0077 | 0.0000 | 0.0174 | 0.0017 | 0.0367 | 0.0156 | 0.0405 | 0.0363 | 0.0656 | 0.0554 | 0.1158 | 0.0606 | 0.1409 | 0.1125 | 0.5753 | 0.7180 | 0.0581 | 0.2857 | 0.0930 | 0.2500 | 0.1860 | 0.1071 | 0.1163 | 0.1786 | 0.1744 | 0.1071 | 0.1163 | 0.0714 | 0.0814 | 0.0000 | 0.1163 | 0.0000 | 0.0581 | 0.0000 | 0.0153 | 0.0337 | 0.0706 | 0.0982 | 0.1135 | 0.1350 | 0.1380 | 0.1503 | 0.2454 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0198 | 11.10 | 4.314 | 0.3248 | 43.9 | 336.777 | 2778.03 | 24382.5 | 0.5530 | 0.1191 | 0.0068 | 0.0000 | 0.0407 | 0.0041 | 0.1143 | 0.0182 | 0.2166 | 0.0597 | 0.2673 | 0.1261 | 0.2088 | 0.2311 | 0.1023 | 0.2725 | 0.0370 | 0.2133 | 0.0062 | 0.0750 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0121 | 0.0032 | 0.0364 | 0.0132 | 0.0907 | 0.0355 | 0.1684 | 0.0778 | 0.2678 | 0.1906 | 0.2778 | 0.3647 | 0.1454 | 0.3144 | 0.1144 | 0.2816 | 0.2397 | 0.3609 | 0.2950 | 0.2346 | 0.1896 | 0.0927 | 0.1073 | 0.0268 | 0.0392 | 0.0034 | 0.0141 | 0.0000 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0090 | 0.0356 | 0.0844 | 0.1569 | 0.2511 | 0.2490 | 0.1644 | 0.0477 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 873 | 826 | 3064 | 6137 | 665.1 | 116.47 | 15.42 | 8.04 | 492 | 567 | 616 | 649 | 680 | 707 | 733 | 763 | 800 | 0.0893 | 548 | 0.993 | 122.00 | 37.22 | 1 | 0.0979 | 300 | 0.0008 | 64.26 | 7.305 | 0.1764 | 455869.0 | 321000000 | 230000000000 | 169000000000000 | 0.4008 | 0.2360 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0026 | 0.0000 | 0.0061 | 0.0010 | 0.0299 | 0.0170 | 0.0464 | 0.0304 | 0.0438 | 0.0180 | 0.0520 | 0.0277 | 0.8189 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0010 | 0.0186 | 0.0166 | 0.0266 | 0.0282 | 0.0190 | 0.0159 | 0.0274 | 0.0239 | 0.9060 | 0.9143 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0031 | 0.0000 | 0.0563 | 0.0000 | 0.0875 | 0.0000 | 0.1125 | 0.0000 | 0.0906 | 0.0000 | 0.1125 | 0.0000 | 0.5313 | 0.0000 | 0.0006 | 0.0053 | 0.0029 | 0.0135 | 0.0224 | 0.0494 | 0.0371 | 0.0530 | 0.8158 | 9 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 25 | 0.3326 | 0.28 | 1.109 | 0.7287 | 302.3 | 7707.87 | 246475 | 9230000 | 0.5740 | 0.1078 | 0.0370 | 0.0041 | 0.0648 | 0.0041 | 0.1039 | 0.0126 | 0.1337 | 0.0236 | 0.1566 | 0.0577 | 0.1880 | 0.1004 | 0.1606 | 0.1497 | 0.1151 | 0.2427 | 0.0403 | 0.4050 | 0.0184 | 0.0004 | 0.0317 | 0.0011 | 0.0455 | 0.0041 | 0.0608 | 0.0114 | 0.0782 | 0.0408 | 0.0945 | 0.0788 | 0.0862 | 0.1063 | 0.1277 | 0.1658 | 0.4570 | 0.5914 | 0.0395 | 0.0410 | 0.0482 | 0.0420 | 0.0556 | 0.0400 | 0.0649 | 0.0470 | 0.0803 | 0.0561 | 0.0770 | 0.0681 | 0.0663 | 0.0681 | 0.1071 | 0.1692 | 0.4612 | 0.4685 | 0.0423 | 0.0379 | 0.0347 | 0.0520 | 0.0863 | 0.1089 | 0.1044 | 0.1262 | 0.4073 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 718 | 209 | 6919 | 20153 | 439.9 | 83.94 | 59.12 | 60.79 | 328 | 364 | 393 | 418 | 442 | 465 | 486 | 511 | 544 | 0.0555 | 1118 | 1.097 | 116.93 | 36.89 | 1 | 0.0405 | 280 | 0.0010 | 31.34 | 7.121 | 0.1942 | 200514.0 | 94500000 | 45900000000 | 23000000000000 | 0.3868 | 0.2525 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0112 | 0.0015 | 0.0437 | 0.0118 | 0.0766 | 0.0244 | 0.0951 | 0.0209 | 0.1280 | 0.0268 | 0.6427 | 0.9146 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0013 | 0.0171 | 0.0100 | 0.0281 | 0.0194 | 0.0344 | 0.0128 | 0.0426 | 0.0172 | 0.8730 | 0.9393 | 0.0040 | 0.0086 | 0.0081 | 0.0000 | 0.0424 | 0.0259 | 0.0727 | 0.2586 | 0.1354 | 0.0862 | 0.1687 | 0.1810 | 0.1343 | 0.1293 | 0.1384 | 0.0431 | 0.2960 | 0.2672 | 0.0003 | 0.0014 | 0.0020 | 0.0108 | 0.0519 | 0.0935 | 0.0896 | 0.1278 | 0.6227 | 8 | 10 | 14 | 25 | 40 | 57 | 76 | 99 | 135 | 0.0457 | 4.18 | 4.483 | 0.5799 | 7190.4 | 1330000 | 338000000 | 109000000000 | 0.4299 | 0.1814 | 0.0071 | 0.0015 | 0.0560 | 0.0042 | 0.1504 | 0.0171 | 0.2041 | 0.0543 | 0.2237 | 0.1277 | 0.1653 | 0.2005 | 0.1077 | 0.1668 | 0.0611 | 0.1704 | 0.0247 | 0.2575 | 0.0002 | 0.0001 | 0.0009 | 0.0008 | 0.0023 | 0.0018 | 0.0122 | 0.0087 | 0.0364 | 0.0271 | 0.0609 | 0.0475 | 0.0552 | 0.0389 | 0.0755 | 0.0611 | 0.7565 | 0.8141 | 0.0011 | 0.0011 | 0.0026 | 0.0037 | 0.0041 | 0.0073 | 0.0192 | 0.0257 | 0.0575 | 0.0690 | 0.0847 | 0.1021 | 0.0802 | 0.0802 | 0.1038 | 0.1182 | 0.6468 | 0.5927 | 0.0005 | 0.0010 | 0.0038 | 0.0132 | 0.0444 | 0.0754 | 0.0604 | 0.0891 | 0.7123 | |||
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 555 | 532 | 3465 | 14759 | 319.8 | 107.54 | 6.73 | 2.27 | 198 | 221 | 243 | 273 | 310 | 350 | 374 | 394 | 435 | 0.0700 | 1033 | 1.221 | 77.39 | 27.66 | 2 | 0.0543 | 188 | 0.0057 | 5.18 | 5.576 | 0.4523 | 113808.0 | 45100000 | 19800000000 | 9650000000000 | 0.4430 | 0.1901 | 0.0028 | 0.0000 | 0.0063 | 0.0000 | 0.0042 | 0.0017 | 0.0245 | 0.0068 | 0.0756 | 0.0345 | 0.1436 | 0.0519 | 0.1289 | 0.0420 | 0.1646 | 0.0615 | 0.4496 | 0.8016 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0004 | 0.0012 | 0.0105 | 0.0031 | 0.0285 | 0.0271 | 0.0558 | 0.0389 | 0.0378 | 0.0249 | 0.0470 | 0.0408 | 0.8187 | 0.8639 | 0.0106 | 0.0000 | 0.0153 | 0.0071 | 0.0188 | 0.0035 | 0.0259 | 0.0390 | 0.0506 | 0.0887 | 0.0576 | 0.0957 | 0.0682 | 0.0780 | 0.0988 | 0.0993 | 0.6541 | 0.5887 | 0.0000 | 0.0024 | 0.0018 | 0.0152 | 0.0328 | 0.0425 | 0.0334 | 0.0468 | 0.8251 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0844 | 0.35 | 0.898 | 0.3300 | 50.5 | 413.246 | 3661.4 | 35082.4 | 0.5392 | 0.1292 | 0.0068 | 0.0003 | 0.0451 | 0.0042 | 0.1067 | 0.0171 | 0.1894 | 0.0476 | 0.2341 | 0.0957 | 0.2205 | 0.1698 | 0.1356 | 0.2507 | 0.0525 | 0.2678 | 0.0093 | 0.1466 | 0.0014 | 0.0002 | 0.0128 | 0.0021 | 0.0344 | 0.0077 | 0.0739 | 0.0219 | 0.1043 | 0.0520 | 0.1474 | 0.0981 | 0.1623 | 0.1436 | 0.2138 | 0.2421 | 0.2497 | 0.4324 | 0.1133 | 0.1976 | 0.1372 | 0.2142 | 0.1664 | 0.1783 | 0.1654 | 0.1636 | 0.1518 | 0.1123 | 0.1186 | 0.0744 | 0.0801 | 0.0372 | 0.0458 | 0.0160 | 0.0213 | 0.0064 | 0.0167 | 0.0531 | 0.0922 | 0.1109 | 0.1310 | 0.1500 | 0.1506 | 0.1588 | 0.1366 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1178 | 674 | 5484 | 6809 | 143.9 | 34.02 | 169.15 | 111.62 | 106 | 116 | 124 | 131 | 139 | 147 | 156 | 168 | 188 | 0.1007 | 686 | 1.157 | 112.97 | 41.40 | 1 | 0.0514 | 282 | 0.0021 | 24.63 | 6.515 | 0.2364 | 21871.4 | 3520000 | 604000000 | 111000000000 | 0.4507 | 0.2018 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0058 | 0.0000 | 0.0260 | 0.0006 | 0.0901 | 0.0200 | 0.1435 | 0.0450 | 0.1588 | 0.0427 | 0.1805 | 0.0719 | 0.3939 | 0.8199 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0104 | 0.0000 | 0.0398 | 0.0138 | 0.0659 | 0.0247 | 0.0797 | 0.0192 | 0.1000 | 0.0332 | 0.7008 | 0.9092 | 0.0032 | 0.0155 | 0.0181 | 0.0217 | 0.0288 | 0.0342 | 0.0703 | 0.1025 | 0.1384 | 0.1460 | 0.1853 | 0.2267 | 0.1289 | 0.0932 | 0.1310 | 0.1211 | 0.2961 | 0.2391 | 0.0017 | 0.0041 | 0.0120 | 0.0398 | 0.0915 | 0.1441 | 0.1151 | 0.1416 | 0.4501 | 48 | 70 | 90 | 115 | 144 | 176 | 214 | 261 | 331 | 0.0020 | 39.25 | 6.753 | 0.2608 | 41068.8 | 12600000 | 4490000000 | 1800000000000 | 0.5577 | 0.1336 | 0.0189 | 0.0007 | 0.0769 | 0.0043 | 0.1858 | 0.0340 | 0.1829 | 0.0814 | 0.2010 | 0.1571 | 0.1647 | 0.2049 | 0.0885 | 0.1545 | 0.0508 | 0.1578 | 0.0305 | 0.2052 | 0.0008 | 0.0000 | 0.0022 | 0.0007 | 0.0047 | 0.0045 | 0.0230 | 0.0137 | 0.0604 | 0.0531 | 0.1187 | 0.0871 | 0.0787 | 0.0745 | 0.1281 | 0.1004 | 0.5833 | 0.6661 | 0.0022 | 0.0048 | 0.0049 | 0.0048 | 0.0153 | 0.0137 | 0.0431 | 0.0642 | 0.0969 | 0.1220 | 0.1620 | 0.1803 | 0.1184 | 0.1214 | 0.1463 | 0.1642 | 0.4109 | 0.3248 | 0.0017 | 0.0017 | 0.0098 | 0.0258 | 0.0834 | 0.1386 | 0.0988 | 0.1449 | 0.4951 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 343 | 200 | 878 | 6143 | 525.5 | 135.86 | 10.24 | 3.28 | 368 | 395 | 421 | 455 | 499 | 554 | 604 | 666 | 723 | 0.0754 | 463 | 0.604 | 47.54 | 9.06 | 1 | 0.1378 | 121 | 0.0024 | 16.27 | 6.196 | 0.2529 | 294575.0 | 175000000 | 110000000000 | 72000000000000 | 0.3830 | 0.2519 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0000 | 0.0375 | 0.0012 | 0.0725 | 0.0436 | 0.1350 | 0.0711 | 0.1250 | 0.0436 | 0.1575 | 0.0748 | 0.4600 | 0.7656 | 0.0016 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0194 | 0.0011 | 0.0387 | 0.0285 | 0.0452 | 0.0582 | 0.0516 | 0.0228 | 0.0613 | 0.0433 | 0.7774 | 0.8461 | 0.0000 | 0.0133 | 0.0000 | 0.0000 | 0.0091 | 0.0000 | 0.0136 | 0.0400 | 0.0500 | 0.1467 | 0.1045 | 0.0533 | 0.0409 | 0.1467 | 0.1000 | 0.1200 | 0.6818 | 0.4800 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0558 | 0.0685 | 0.0482 | 0.0635 | 0.7589 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 0.0096 | 13.75 | 5.010 | 0.2956 | 115.7 | 1428.61 | 19209.6 | 280803 | 0.4694 | 0.1709 | 0.0114 | 0.0012 | 0.0485 | 0.0043 | 0.1058 | 0.0137 | 0.1831 | 0.0308 | 0.2262 | 0.0599 | 0.2172 | 0.1118 | 0.1379 | 0.2167 | 0.0576 | 0.3023 | 0.0124 | 0.2592 | 0.0018 | 0.0000 | 0.0061 | 0.0002 | 0.0167 | 0.0017 | 0.0338 | 0.0093 | 0.0686 | 0.0222 | 0.1093 | 0.0398 | 0.1662 | 0.0718 | 0.2592 | 0.1976 | 0.3384 | 0.6574 | 0.0758 | 0.1652 | 0.1178 | 0.1845 | 0.1375 | 0.1674 | 0.1437 | 0.1330 | 0.1277 | 0.0848 | 0.1313 | 0.0730 | 0.0882 | 0.0655 | 0.0903 | 0.0612 | 0.0877 | 0.0655 | 0.0141 | 0.0392 | 0.0707 | 0.1082 | 0.1172 | 0.1593 | 0.1694 | 0.1593 | 0.1625 |