High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 404 | 381 | 364 | 11109 | 91.1 | 12.14 | 8.23 | 2.31 | 76 | 80 | 84 | 87 | 91 | 94 | 97 | 101 | 107 | 0.0564 | 627 | 0.370 | 126.83 | 26.31 | 1 | 1.2060 | 439 | 0.0718 | 0.71 | 2.815 | 0.7088 | 8437.9 | 795470 | 76300000 | 7430000000 | 0.3908 | 0.2100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0192 | 0.0055 | 0.0895 | 0.0714 | 0.1789 | 0.1099 | 0.1278 | 0.0604 | 0.1917 | 0.1044 | 0.3930 | 0.6484 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0117 | 0.0055 | 0.0787 | 0.0714 | 0.1254 | 0.1099 | 0.0671 | 0.0604 | 0.1195 | 0.1044 | 0.5977 | 0.6484 | 0.0333 | 0.0000 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.1333 | 0.0000 | 0.2000 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.0055 | 0.0055 | 0.0055 | 0.0546 | 0.1421 | 0.1694 | 0.1038 | 0.1639 | 0.3497 | 5 | 6 | 7 | 8 | 8 | 9 | 9 | 10 | 11 | 0.2651 | 0.45 | 1.038 | 0.6298 | 73.1 | 692.301 | 6934.55 | 73026.4 | 0.5150 | 0.1470 | 0.0084 | 0.0000 | 0.0454 | 0.0006 | 0.1209 | 0.0027 | 0.2055 | 0.0101 | 0.2489 | 0.0293 | 0.2133 | 0.0743 | 0.1150 | 0.1788 | 0.0368 | 0.3510 | 0.0059 | 0.3532 | 0.0002 | 0.0000 | 0.0024 | 0.0000 | 0.0090 | 0.0002 | 0.0345 | 0.0025 | 0.0902 | 0.0128 | 0.1613 | 0.0328 | 0.2251 | 0.0673 | 0.2757 | 0.2320 | 0.2014 | 0.6524 | 0.0871 | 0.3913 | 0.1762 | 0.3337 | 0.2103 | 0.1554 | 0.1847 | 0.0633 | 0.1500 | 0.0368 | 0.1089 | 0.0161 | 0.0537 | 0.0035 | 0.0237 | 0.0000 | 0.0054 | 0.0000 | 0.0034 | 0.0150 | 0.0465 | 0.1072 | 0.1765 | 0.2248 | 0.1975 | 0.1520 | 0.0770 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 935 | 650 | 4467 | 9610 | 94.8 | 24.92 | 207.00 | 159.98 | 69 | 75 | 80 | 84 | 89 | 95 | 102 | 111 | 128 | 0.0728 | 700 | 0.935 | 58.80 | 21.38 | 2 | 0.0374 | 167 | 0.0023 | 22.65 | 6.438 | 0.2515 | 9610.2 | 1050000 | 124000000 | 15700000000 | 0.4444 | 0.2134 | 0.0007 | 0.0000 | 0.0055 | 0.0010 | 0.0092 | 0.0005 | 0.0283 | 0.0039 | 0.0881 | 0.0217 | 0.1418 | 0.0440 | 0.1686 | 0.0426 | 0.1851 | 0.0733 | 0.3728 | 0.8130 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0048 | 0.0000 | 0.0127 | 0.0016 | 0.0469 | 0.0122 | 0.0720 | 0.0228 | 0.0813 | 0.0176 | 0.1042 | 0.0375 | 0.6764 | 0.9083 | 0.0098 | 0.0137 | 0.0147 | 0.0000 | 0.0244 | 0.0192 | 0.0452 | 0.0658 | 0.1345 | 0.1699 | 0.1516 | 0.2000 | 0.1186 | 0.1151 | 0.1528 | 0.1699 | 0.3484 | 0.2466 | 0.0039 | 0.0055 | 0.0171 | 0.0473 | 0.0892 | 0.1244 | 0.1007 | 0.1172 | 0.4948 | 54 | 84 | 111 | 137 | 168 | 203 | 242 | 303 | 400 | 0.0032 | 28.25 | 6.373 | 0.3196 | 68440.7 | 32700000 | 20600000000 | 15800000000000 | 0.5401 | 0.1476 | 0.0155 | 0.0007 | 0.0447 | 0.0007 | 0.1182 | 0.0190 | 0.1771 | 0.0542 | 0.2087 | 0.1259 | 0.1908 | 0.1667 | 0.1258 | 0.1621 | 0.0810 | 0.1828 | 0.0382 | 0.2878 | 0.0008 | 0.0002 | 0.0010 | 0.0003 | 0.0045 | 0.0026 | 0.0207 | 0.0082 | 0.0649 | 0.0465 | 0.1107 | 0.0798 | 0.0944 | 0.0796 | 0.1265 | 0.1118 | 0.5765 | 0.6712 | 0.0018 | 0.0019 | 0.0080 | 0.0062 | 0.0123 | 0.0162 | 0.0355 | 0.0380 | 0.0952 | 0.1102 | 0.1509 | 0.1501 | 0.0955 | 0.1083 | 0.1404 | 0.1406 | 0.4604 | 0.4285 | 0.0005 | 0.0013 | 0.0099 | 0.0259 | 0.0863 | 0.1255 | 0.0978 | 0.1408 | 0.5120 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 462 | 109 | 459 | 1169 | 64.3 | 13.23 | 8.02 | 2.47 | 48 | 52 | 57 | 61 | 64 | 67 | 71 | 74 | 79 | 0.2515 | 294 | 0.892 | 64.33 | 20.81 | 1 | 0.3791 | 174 | 0.0526 | 1.06 | 3.212 | 0.6390 | 4308.5 | 301320 | 22000000 | 1690000000 | 0.4020 | 0.2263 | 0.0000 | 0.0000 | 0.0063 | 0.0023 | 0.0094 | 0.0068 | 0.0408 | 0.0068 | 0.0940 | 0.0502 | 0.1160 | 0.1073 | 0.1473 | 0.0662 | 0.2508 | 0.0936 | 0.3354 | 0.6667 | 0.0000 | 0.0000 | 0.0026 | 0.0022 | 0.0026 | 0.0066 | 0.0238 | 0.0044 | 0.0556 | 0.0462 | 0.0635 | 0.0879 | 0.0714 | 0.0505 | 0.1111 | 0.0725 | 0.6693 | 0.7297 | 0.0678 | 0.0000 | 0.0508 | 0.0000 | 0.1356 | 0.0588 | 0.0339 | 0.1176 | 0.2034 | 0.2941 | 0.1186 | 0.1176 | 0.0678 | 0.1176 | 0.1356 | 0.2353 | 0.1864 | 0.0588 | 0.0041 | 0.0041 | 0.0245 | 0.0245 | 0.0735 | 0.0939 | 0.0898 | 0.1796 | 0.5061 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0200 | 12.70 | 4.330 | 0.3019 | 70.5 | 664.57 | 6651.59 | 70129.1 | 0.5248 | 0.1240 | 0.0136 | 0.0000 | 0.0492 | 0.0010 | 0.1121 | 0.0149 | 0.2462 | 0.0378 | 0.2394 | 0.0746 | 0.2190 | 0.1303 | 0.1002 | 0.2139 | 0.0187 | 0.2806 | 0.0017 | 0.2468 | 0.0000 | 0.0000 | 0.0099 | 0.0009 | 0.0221 | 0.0027 | 0.0585 | 0.0220 | 0.1170 | 0.0577 | 0.2064 | 0.0843 | 0.2274 | 0.1357 | 0.2506 | 0.2878 | 0.1082 | 0.4088 | 0.1199 | 0.5814 | 0.2461 | 0.2907 | 0.2366 | 0.0814 | 0.1924 | 0.0349 | 0.1293 | 0.0116 | 0.0536 | 0.0000 | 0.0158 | 0.0000 | 0.0032 | 0.0000 | 0.0032 | 0.0000 | 0.0126 | 0.0535 | 0.1258 | 0.2013 | 0.2186 | 0.1714 | 0.1336 | 0.0708 | 0.0126 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 765 | 448 | 1036 | 4704 | 600.2 | 210.48 | 6.20 | 1.84 | 332 | 391 | 444 | 509 | 577 | 659 | 743 | 818 | 904 | 0.0897 | 422 | 1.225 | 53.31 | 21.95 | 1 | 0.1332 | 138 | 0.0016 | 24.08 | 6.554 | 0.2404 | 404516.0 | 298000000 | 234000000000 | 192000000000000 | 0.3419 | 0.2894 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0031 | 0.0043 | 0.1242 | 0.0558 | 0.2329 | 0.1016 | 0.1304 | 0.0629 | 0.1739 | 0.0801 | 0.3354 | 0.6938 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0392 | 0.0339 | 0.0633 | 0.0532 | 0.0271 | 0.0271 | 0.0542 | 0.0407 | 0.8163 | 0.8439 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0324 | 0.0585 | 0.0649 | 0.0848 | 0.1135 | 0.0409 | 0.0757 | 0.0673 | 0.0811 | 0.7427 | 0.6324 | 0.0000 | 0.0000 | 0.0021 | 0.0062 | 0.0374 | 0.0811 | 0.0395 | 0.0457 | 0.7879 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 0.0274 | 6.20 | 3.980 | 0.3875 | 41.8 | 302.145 | 2320.55 | 18932.6 | 0.4537 | 0.1856 | 0.0023 | 0.0005 | 0.0113 | 0.0013 | 0.0441 | 0.0090 | 0.1027 | 0.0249 | 0.1782 | 0.0542 | 0.2398 | 0.1111 | 0.2262 | 0.2325 | 0.1613 | 0.3262 | 0.0341 | 0.2402 | 0.0000 | 0.0000 | 0.0017 | 0.0005 | 0.0047 | 0.0016 | 0.0231 | 0.0099 | 0.0540 | 0.0309 | 0.1005 | 0.0574 | 0.1816 | 0.1030 | 0.3028 | 0.2870 | 0.3314 | 0.5097 | 0.1740 | 0.3416 | 0.2290 | 0.2805 | 0.1980 | 0.1584 | 0.1530 | 0.1041 | 0.1140 | 0.0679 | 0.0770 | 0.0181 | 0.0260 | 0.0158 | 0.0230 | 0.0090 | 0.0060 | 0.0045 | 0.0029 | 0.0141 | 0.0417 | 0.0959 | 0.1617 | 0.2172 | 0.2159 | 0.1543 | 0.0962 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 897 | 352 | 491 | 10165 | 31.2 | 10.66 | 5.57 | 2.04 | 21 | 23 | 24 | 26 | 27 | 30 | 34 | 40 | 49 | 0.0858 | 872 | 0.813 | 87.21 | 20.59 | 5 | 0.4073 | 200 | 0.0618 | 0.76 | 3.150 | 0.6872 | 1083.9 | 42132.6 | 1810000 | 83600000 | 0.3481 | 0.2731 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0187 | 0.0025 | 0.0561 | 0.0150 | 0.1168 | 0.0848 | 0.2336 | 0.0798 | 0.1963 | 0.0873 | 0.1869 | 0.1446 | 0.1729 | 0.5860 | 0.0061 | 0.0000 | 0.0061 | 0.0000 | 0.0122 | 0.0021 | 0.0334 | 0.0125 | 0.0608 | 0.0582 | 0.0912 | 0.0353 | 0.0821 | 0.0561 | 0.1003 | 0.0811 | 0.6079 | 0.7547 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0348 | 0.0625 | 0.0609 | 0.0500 | 0.1391 | 0.1625 | 0.0609 | 0.1125 | 0.1043 | 0.0750 | 0.6000 | 0.5375 | 0.0000 | 0.0107 | 0.0000 | 0.0481 | 0.0428 | 0.1070 | 0.0695 | 0.1016 | 0.6203 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0061 | 0.11 | 0.381 | 0.0699 | 35.2 | 247.481 | 1925.98 | 16644.2 | 0.5163 | 0.1494 | 0.0075 | 0.0004 | 0.0317 | 0.0014 | 0.1096 | 0.0083 | 0.1889 | 0.0233 | 0.2557 | 0.0515 | 0.2310 | 0.1180 | 0.1247 | 0.2326 | 0.0447 | 0.3477 | 0.0060 | 0.2168 | 0.0016 | 0.0000 | 0.0075 | 0.0002 | 0.0348 | 0.0045 | 0.0908 | 0.0154 | 0.1571 | 0.0325 | 0.2323 | 0.0692 | 0.2275 | 0.1499 | 0.1597 | 0.3269 | 0.0887 | 0.4014 | 0.2469 | 0.4372 | 0.2984 | 0.2271 | 0.1850 | 0.0804 | 0.0888 | 0.0635 | 0.0564 | 0.0536 | 0.0355 | 0.0409 | 0.0392 | 0.0381 | 0.0282 | 0.0381 | 0.0214 | 0.0212 | 0.0197 | 0.0760 | 0.1532 | 0.2101 | 0.1844 | 0.1602 | 0.1001 | 0.0600 | 0.0363 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 181 | 254 | 1614 | 11324 | 1117.5 | 296.73 | 9.91 | 3.01 | 735 | 828 | 914 | 1000 | 1089 | 1176 | 1265 | 1423 | 1565 | 0.0770 | 872 | 1.072 | 79.08 | 22.56 | 2 | 0.1121 | 181 | 0.0011 | 52.02 | 6.977 | 0.1957 | 1340000.0 | 1700000000 | 2270000000000 | 3.16E+15 | 0.3925 | 0.2330 | 0.0013 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0043 | 0.0090 | 0.0078 | 0.0859 | 0.0456 | 0.1538 | 0.0820 | 0.1013 | 0.0520 | 0.1115 | 0.0834 | 0.5372 | 0.7242 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0043 | 0.0058 | 0.0445 | 0.0358 | 0.0676 | 0.0588 | 0.0360 | 0.0371 | 0.0668 | 0.0543 | 0.7800 | 0.8056 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0124 | 0.0103 | 0.0248 | 0.0490 | 0.0745 | 0.0979 | 0.1242 | 0.0515 | 0.0745 | 0.0670 | 0.1304 | 0.7242 | 0.5528 | 0.0000 | 0.0000 | 0.0013 | 0.0066 | 0.0584 | 0.0717 | 0.0491 | 0.0704 | 0.7424 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 12 | 14 | 0.4427 | 0.33 | 0.894 | 0.7893 | 107.3 | 1247.66 | 15428.7 | 201459 | 0.5329 | 0.1343 | 0.0090 | 0.0001 | 0.0432 | 0.0015 | 0.1219 | 0.0064 | 0.2092 | 0.0237 | 0.2630 | 0.0647 | 0.2046 | 0.1320 | 0.1129 | 0.2428 | 0.0316 | 0.3164 | 0.0048 | 0.2124 | 0.0001 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0008 | 0.0360 | 0.0079 | 0.0843 | 0.0254 | 0.1595 | 0.0409 | 0.2364 | 0.0926 | 0.2711 | 0.2669 | 0.1995 | 0.5654 | 0.0875 | 0.2991 | 0.1970 | 0.2991 | 0.2239 | 0.2057 | 0.2071 | 0.1218 | 0.1517 | 0.0503 | 0.0847 | 0.0160 | 0.0376 | 0.0044 | 0.0092 | 0.0036 | 0.0012 | 0.0000 | 0.0072 | 0.0439 | 0.0969 | 0.1605 | 0.2046 | 0.1989 | 0.1608 | 0.0959 | 0.0313 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 402 | 136 | 3297 | 12148 | 98.0 | 18.33 | 8.19 | 2.60 | 74 | 80 | 85 | 92 | 97 | 103 | 108 | 114 | 123 | 0.0740 | 899 | 0.685 | 83.76 | 26.42 | 1 | 0.0746 | 246 | 0.0399 | 0.86 | 3.490 | 0.6974 | 9940.2 | 1040000 | 113000000 | 12600000000 | 0.4461 | 0.1984 | 0.0050 | 0.0003 | 0.0077 | 0.0000 | 0.0149 | 0.0019 | 0.0398 | 0.0046 | 0.0430 | 0.0207 | 0.0742 | 0.0377 | 0.0972 | 0.0303 | 0.1470 | 0.0585 | 0.5712 | 0.8460 | 0.0026 | 0.0000 | 0.0018 | 0.0000 | 0.0048 | 0.0015 | 0.0183 | 0.0033 | 0.0202 | 0.0176 | 0.0352 | 0.0303 | 0.0421 | 0.0218 | 0.0546 | 0.0331 | 0.8204 | 0.8923 | 0.0251 | 0.0625 | 0.0309 | 0.0625 | 0.0502 | 0.1719 | 0.0598 | 0.1563 | 0.0927 | 0.1875 | 0.1544 | 0.1406 | 0.1216 | 0.0938 | 0.1564 | 0.0781 | 0.3089 | 0.0469 | 0.0024 | 0.0036 | 0.0134 | 0.0243 | 0.0389 | 0.0584 | 0.0833 | 0.1217 | 0.6539 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0144 | 12.37 | 4.643 | 0.3155 | 73.9 | 721.847 | 7566.38 | 84525.8 | 0.5238 | 0.1413 | 0.0153 | 0.0002 | 0.0771 | 0.0016 | 0.1639 | 0.0070 | 0.2274 | 0.0223 | 0.2309 | 0.0551 | 0.1655 | 0.1102 | 0.0864 | 0.1993 | 0.0283 | 0.3127 | 0.0052 | 0.2916 | 0.0011 | 0.0000 | 0.0072 | 0.0003 | 0.0296 | 0.0015 | 0.0604 | 0.0068 | 0.1020 | 0.0189 | 0.1625 | 0.0400 | 0.2241 | 0.0871 | 0.2509 | 0.2788 | 0.1621 | 0.5666 | 0.0905 | 0.3211 | 0.1651 | 0.2629 | 0.2052 | 0.1761 | 0.1949 | 0.1076 | 0.1565 | 0.0717 | 0.0987 | 0.0351 | 0.0583 | 0.0215 | 0.0222 | 0.0032 | 0.0085 | 0.0008 | 0.0051 | 0.0284 | 0.0735 | 0.1320 | 0.1649 | 0.1938 | 0.1874 | 0.1443 | 0.0706 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 287 | 523 | 301 | 5124 | 89.9 | 7.90 | 7.40 | 2.14 | 79 | 82 | 86 | 88 | 90 | 93 | 95 | 97 | 100 | 0.0720 | 369 | 0.946 | 37.36 | 10.77 | 0 | 0.3223 | 97 | 0.1482 | 0.45 | 2.153 | 0.7860 | 8141.3 | 742840 | 68300000 | 6310000000 | 0.3690 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0120 | 0.0120 | 0.0542 | 0.0482 | 0.0783 | 0.1205 | 0.1084 | 0.5663 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1708 | 0.51 | 1.021 | 0.4581 | 59.3 | 508.117 | 4604.6 | 43888.8 | 0.4666 | 0.2005 | 0.0058 | 0.0003 | 0.0341 | 0.0016 | 0.0942 | 0.0123 | 0.1790 | 0.0503 | 0.2344 | 0.1168 | 0.2308 | 0.1953 | 0.1477 | 0.2794 | 0.0651 | 0.2535 | 0.0090 | 0.0906 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0070 | 0.0015 | 0.0224 | 0.0088 | 0.0627 | 0.0354 | 0.1193 | 0.0626 | 0.1833 | 0.1375 | 0.3291 | 0.3390 | 0.2756 | 0.4152 | 0.0900 | 0.2589 | 0.1985 | 0.3018 | 0.2363 | 0.2417 | 0.2038 | 0.1227 | 0.1456 | 0.0577 | 0.0887 | 0.0135 | 0.0278 | 0.0025 | 0.0093 | 0.0012 | 0.0000 | 0.0000 | 0.0003 | 0.0097 | 0.0436 | 0.0951 | 0.1730 | 0.2360 | 0.2304 | 0.1642 | 0.0477 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 477 | 785 | 2057 | 7126 | 15.8 | 5.35 | 5.58 | 1.94 | 10 | 11 | 13 | 14 | 15 | 16 | 18 | 20 | 22 | 0.1343 | 957 | 1.077 | 39.62 | 14.00 | 0 | 0.0501 | 103 | 0.0083 | 6.76 | 5.098 | 0.3940 | 278.8 | 5536.95 | 125712 | 3300000 | 0.3803 | 0.2578 | 0.0068 | 0.0000 | 0.0241 | 0.0017 | 0.0395 | 0.0081 | 0.0656 | 0.0237 | 0.1070 | 0.0317 | 0.1466 | 0.0531 | 0.1688 | 0.1073 | 0.2054 | 0.1604 | 0.2363 | 0.6140 | 0.0048 | 0.0000 | 0.0131 | 0.0010 | 0.0220 | 0.0068 | 0.0275 | 0.0167 | 0.0440 | 0.0256 | 0.0557 | 0.0329 | 0.0688 | 0.0605 | 0.0922 | 0.0924 | 0.6717 | 0.7641 | 0.0168 | 0.0437 | 0.0216 | 0.0437 | 0.0481 | 0.0328 | 0.0793 | 0.0656 | 0.0865 | 0.1038 | 0.1346 | 0.1093 | 0.1298 | 0.0710 | 0.1394 | 0.1749 | 0.3438 | 0.3552 | 0.0178 | 0.0231 | 0.0241 | 0.0409 | 0.0409 | 0.0682 | 0.0860 | 0.1091 | 0.5897 | 3 | 4 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0254 | 8.33 | 4.093 | 0.3635 | 34.9 | 237.89 | 1743 | 13611.8 | 0.5441 | 0.1416 | 0.0029 | 0.0002 | 0.0262 | 0.0017 | 0.0867 | 0.0113 | 0.1633 | 0.0354 | 0.2318 | 0.0789 | 0.2315 | 0.1447 | 0.1584 | 0.2575 | 0.0821 | 0.2968 | 0.0170 | 0.1734 | 0.0004 | 0.0002 | 0.0045 | 0.0006 | 0.0189 | 0.0043 | 0.0680 | 0.0220 | 0.1231 | 0.0509 | 0.2194 | 0.0876 | 0.2719 | 0.1709 | 0.2172 | 0.3403 | 0.0767 | 0.3232 | 0.2384 | 0.4990 | 0.3216 | 0.3638 | 0.2659 | 0.1113 | 0.1235 | 0.0258 | 0.0369 | 0.0000 | 0.0129 | 0.0000 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0115 | 0.0662 | 0.1649 | 0.2477 | 0.2359 | 0.1587 | 0.0825 | 0.0266 | 0.0059 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 448 | 583 | 4870 | 11803 | 145.2 | 35.55 | 166.28 | 141.22 | 106 | 119 | 129 | 136 | 143 | 150 | 157 | 166 | 182 | 0.0848 | 1001 | 1.080 | 90.80 | 26.02 | 1 | 0.0448 | 218 | 0.0023 | 21.25 | 6.376 | 0.2593 | 22352.9 | 3700000 | 674000000 | 140000000000 | 0.5233 | 0.1537 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0063 | 0.0020 | 0.0186 | 0.0059 | 0.0714 | 0.0204 | 0.1461 | 0.0576 | 0.1467 | 0.0492 | 0.1833 | 0.0730 | 0.4263 | 0.7916 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0017 | 0.0013 | 0.0087 | 0.0044 | 0.0397 | 0.0176 | 0.0788 | 0.0439 | 0.0694 | 0.0279 | 0.1031 | 0.0468 | 0.6983 | 0.8580 | 0.0071 | 0.0138 | 0.0228 | 0.0276 | 0.0342 | 0.0369 | 0.1198 | 0.1244 | 0.1641 | 0.1982 | 0.1897 | 0.1935 | 0.1227 | 0.0599 | 0.1098 | 0.1152 | 0.2297 | 0.2304 | 0.0030 | 0.0056 | 0.0155 | 0.0494 | 0.0975 | 0.1375 | 0.1224 | 0.1538 | 0.4154 | 18 | 39 | 68 | 100 | 133 | 170 | 213 | 270 | 362 | 0.0037 | 57.89 | 6.920 | 0.2988 | 47591.3 | 18100000 | 8370000000 | 4450000000000 | 0.4521 | 0.1774 | 0.0099 | 0.0010 | 0.0727 | 0.0018 | 0.1824 | 0.0223 | 0.1760 | 0.0674 | 0.2042 | 0.1490 | 0.1715 | 0.2039 | 0.0989 | 0.1663 | 0.0578 | 0.1655 | 0.0267 | 0.2229 | 0.0002 | 0.0000 | 0.0010 | 0.0008 | 0.0039 | 0.0034 | 0.0108 | 0.0072 | 0.0510 | 0.0340 | 0.0877 | 0.0683 | 0.0730 | 0.0617 | 0.1087 | 0.0831 | 0.6637 | 0.7415 | 0.0013 | 0.0019 | 0.0013 | 0.0061 | 0.0077 | 0.0145 | 0.0286 | 0.0352 | 0.0848 | 0.1044 | 0.1358 | 0.1322 | 0.1054 | 0.1131 | 0.1247 | 0.1251 | 0.5106 | 0.4674 | 0.0006 | 0.0029 | 0.0045 | 0.0181 | 0.0642 | 0.1082 | 0.0990 | 0.1199 | 0.5826 | |||
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 835 | 674 | 1286 | 9006 | 107.9 | 35.92 | 236.20 | 179.35 | 71 | 83 | 90 | 96 | 102 | 108 | 115 | 126 | 148 | 0.0815 | 734 | 0.834 | 60.64 | 18.97 | 2 | 0.1260 | 162 | 0.0037 | 21.25 | 5.914 | 0.2852 | 12925.5 | 1750000 | 272000000 | 48100000000 | 0.4873 | 0.1534 | 0.0027 | 0.0000 | 0.0054 | 0.0036 | 0.0308 | 0.0055 | 0.0496 | 0.0173 | 0.1300 | 0.0656 | 0.1662 | 0.0911 | 0.1421 | 0.0647 | 0.1568 | 0.1047 | 0.3164 | 0.6475 | 0.0000 | 0.0000 | 0.0031 | 0.0016 | 0.0134 | 0.0033 | 0.0237 | 0.0124 | 0.0792 | 0.0437 | 0.1132 | 0.0766 | 0.0792 | 0.0445 | 0.1091 | 0.0807 | 0.5792 | 0.7372 | 0.0088 | 0.0086 | 0.0088 | 0.0172 | 0.0265 | 0.0172 | 0.0929 | 0.0862 | 0.1106 | 0.1034 | 0.1593 | 0.1724 | 0.0885 | 0.0690 | 0.1283 | 0.1379 | 0.3761 | 0.3879 | 0.0038 | 0.0095 | 0.0302 | 0.0624 | 0.1078 | 0.1229 | 0.1096 | 0.1153 | 0.4386 | 21 | 54 | 101 | 156 | 212 | 269 | 324 | 398 | 492 | 0.0054 | 44.25 | 6.916 | 0.2857 | 87951.8 | 39600000 | 20100000000 | 11200000000000 | 0.5258 | 0.1424 | 0.0084 | 0.0013 | 0.0560 | 0.0023 | 0.1925 | 0.0179 | 0.2183 | 0.0737 | 0.2022 | 0.1661 | 0.1481 | 0.2268 | 0.0959 | 0.1657 | 0.0541 | 0.1561 | 0.0245 | 0.1900 | 0.0002 | 0.0002 | 0.0010 | 0.0009 | 0.0047 | 0.0025 | 0.0137 | 0.0101 | 0.0490 | 0.0402 | 0.0890 | 0.0809 | 0.0733 | 0.0592 | 0.1002 | 0.0870 | 0.6689 | 0.7190 | 0.0012 | 0.0019 | 0.0030 | 0.0054 | 0.0075 | 0.0103 | 0.0251 | 0.0387 | 0.0681 | 0.0831 | 0.1282 | 0.1543 | 0.1091 | 0.1091 | 0.1372 | 0.1313 | 0.5206 | 0.4659 | 0.0007 | 0.0036 | 0.0053 | 0.0177 | 0.0540 | 0.1087 | 0.0856 | 0.1201 | 0.6042 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 176 | 439 | 2149 | 10252 | 192.6 | 59.91 | 8.87 | 3.44 | 120 | 133 | 148 | 165 | 184 | 205 | 228 | 254 | 283 | 0.0694 | 712 | 0.822 | 57.98 | 20.03 | 1 | 0.0814 | 175 | 0.0084 | 2.12 | 4.986 | 0.5414 | 40700.9 | 9310000 | 2270000000 | 578000000000 | 0.3740 | 0.2645 | 0.0013 | 0.0012 | 0.0076 | 0.0030 | 0.0076 | 0.0041 | 0.0278 | 0.0100 | 0.0682 | 0.0349 | 0.1174 | 0.0573 | 0.1023 | 0.0473 | 0.1452 | 0.0810 | 0.5227 | 0.7612 | 0.0000 | 0.0010 | 0.0043 | 0.0020 | 0.0021 | 0.0030 | 0.0100 | 0.0070 | 0.0242 | 0.0214 | 0.0356 | 0.0349 | 0.0342 | 0.0244 | 0.0456 | 0.0449 | 0.8439 | 0.8614 | 0.0000 | 0.0064 | 0.0000 | 0.0032 | 0.0065 | 0.0127 | 0.0196 | 0.0255 | 0.0344 | 0.0541 | 0.0687 | 0.0637 | 0.0507 | 0.0732 | 0.0589 | 0.0669 | 0.7610 | 0.6943 | 0.0000 | 0.0000 | 0.0072 | 0.0196 | 0.0319 | 0.0330 | 0.0484 | 0.0649 | 0.7951 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 0.0123 | 12.27 | 4.870 | 0.3144 | 90.5 | 1065.26 | 14510.9 | 227463 | 0.4586 | 0.1831 | 0.0295 | 0.0009 | 0.1028 | 0.0024 | 0.1962 | 0.0094 | 0.2565 | 0.0319 | 0.2244 | 0.0719 | 0.1268 | 0.1660 | 0.0511 | 0.2677 | 0.0112 | 0.2954 | 0.0016 | 0.1543 | 0.0050 | 0.0000 | 0.0247 | 0.0004 | 0.0691 | 0.0026 | 0.1247 | 0.0146 | 0.1520 | 0.0414 | 0.1628 | 0.1000 | 0.1487 | 0.1803 | 0.1348 | 0.2780 | 0.1782 | 0.3828 | 0.1256 | 0.1981 | 0.1426 | 0.1338 | 0.1343 | 0.1060 | 0.1181 | 0.0730 | 0.1121 | 0.0782 | 0.0895 | 0.0773 | 0.0642 | 0.0695 | 0.0701 | 0.0712 | 0.1434 | 0.1929 | 0.0242 | 0.0702 | 0.1099 | 0.1423 | 0.1381 | 0.1306 | 0.1204 | 0.1069 | 0.1574 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 227 | 700 | 2457 | 15737 | 289.2 | 101.50 | 9.59 | 3.09 | 185 | 205 | 224 | 243 | 262 | 282 | 308 | 358 | 452 | 0.0555 | 874 | 1.038 | 40.80 | 14.42 | 1 | 0.0456 | 112 | 0.0046 | 7.54 | 5.814 | 0.3959 | 93934.6 | 34400000 | 14000000000 | 6220000000000 | 0.3996 | 0.2284 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0010 | 0.0200 | 0.0095 | 0.0763 | 0.0322 | 0.1117 | 0.0548 | 0.0981 | 0.0497 | 0.1154 | 0.0724 | 0.5722 | 0.7804 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0008 | 0.0110 | 0.0064 | 0.0318 | 0.0187 | 0.0434 | 0.0314 | 0.0446 | 0.0263 | 0.0532 | 0.0403 | 0.8128 | 0.8760 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0019 | 0.0027 | 0.0206 | 0.0247 | 0.0468 | 0.0630 | 0.0880 | 0.0904 | 0.0637 | 0.0685 | 0.0787 | 0.0986 | 0.6966 | 0.6521 | 0.0011 | 0.0022 | 0.0043 | 0.0183 | 0.0539 | 0.0766 | 0.0583 | 0.0798 | 0.7055 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 12 | 14 | 0.0103 | 12.47 | 4.932 | 0.3085 | 101.5 | 1173.91 | 14746.7 | 200713 | 0.4806 | 0.1663 | 0.0121 | 0.0008 | 0.0519 | 0.0024 | 0.1150 | 0.0081 | 0.1984 | 0.0215 | 0.2311 | 0.0482 | 0.1959 | 0.0974 | 0.1331 | 0.1901 | 0.0517 | 0.3239 | 0.0108 | 0.3077 | 0.0032 | 0.0001 | 0.0147 | 0.0004 | 0.0283 | 0.0024 | 0.0519 | 0.0078 | 0.0814 | 0.0224 | 0.1134 | 0.0398 | 0.1727 | 0.0801 | 0.2397 | 0.2135 | 0.2946 | 0.6336 | 0.0921 | 0.2202 | 0.1323 | 0.1939 | 0.1418 | 0.1653 | 0.1471 | 0.1289 | 0.1473 | 0.1008 | 0.1225 | 0.0776 | 0.0936 | 0.0519 | 0.0695 | 0.0328 | 0.0537 | 0.0286 | 0.0234 | 0.0575 | 0.0810 | 0.1141 | 0.1428 | 0.1680 | 0.1726 | 0.1435 | 0.0970 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 340 | 406 | 471 | 6514 | 857.4 | 228.67 | 9.61 | 2.99 | 549 | 627 | 690 | 770 | 842 | 920 | 1002 | 1103 | 1189 | 0.0711 | 463 | 1.310 | 25.32 | 10.63 | 1 | 0.1423 | 67 | 0.0025 | 78.35 | 6.025 | 0.1012 | 787377.0 | 767000000 | 784000000000 | 832000000000000 | 0.3659 | 0.2545 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0099 | 0.0024 | 0.1034 | 0.0622 | 0.2512 | 0.0909 | 0.1281 | 0.0646 | 0.1823 | 0.0933 | 0.3251 | 0.6866 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0022 | 0.0515 | 0.0500 | 0.0879 | 0.0609 | 0.0424 | 0.0391 | 0.0515 | 0.0543 | 0.7606 | 0.7935 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0476 | 0.0787 | 0.1667 | 0.1496 | 0.1667 | 0.0315 | 0.0952 | 0.1260 | 0.1667 | 0.6063 | 0.3571 | 0.0000 | 0.0000 | 0.0000 | 0.0089 | 0.0536 | 0.1161 | 0.0402 | 0.0714 | 0.7098 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 12 | 13 | 0.0120 | 10.83 | 4.800 | 0.3191 | 101.2 | 1165.12 | 14657.4 | 201923 | 0.4760 | 0.1625 | 0.0062 | 0.0009 | 0.0309 | 0.0025 | 0.0752 | 0.0063 | 0.1498 | 0.0201 | 0.2096 | 0.0366 | 0.2372 | 0.0807 | 0.1938 | 0.1532 | 0.0783 | 0.3133 | 0.0190 | 0.3862 | 0.0016 | 0.0000 | 0.0096 | 0.0007 | 0.0200 | 0.0031 | 0.0446 | 0.0111 | 0.0824 | 0.0214 | 0.1177 | 0.0415 | 0.1815 | 0.0663 | 0.2235 | 0.1853 | 0.3192 | 0.6707 | 0.1143 | 0.2295 | 0.1414 | 0.1525 | 0.1455 | 0.1311 | 0.1299 | 0.0803 | 0.1225 | 0.0738 | 0.1049 | 0.0754 | 0.0683 | 0.0623 | 0.0751 | 0.1049 | 0.0981 | 0.0902 | 0.0313 | 0.0568 | 0.1064 | 0.1471 | 0.1279 | 0.1328 | 0.1432 | 0.1233 | 0.1312 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 389 | 150 | 4606 | 15170 | 424.9 | 103.36 | 120.09 | 186.60 | 306 | 339 | 363 | 386 | 408 | 432 | 458 | 507 | 588 | 0.0560 | 850 | 1.111 | 95.13 | 27.89 | 1 | 0.0480 | 221 | 0.0012 | 30.61 | 6.994 | 0.2232 | 191216.0 | 91000000 | 45700000000 | 24100000000000 | 0.4331 | 0.2087 | 0.0004 | 0.0000 | 0.0014 | 0.0005 | 0.0043 | 0.0024 | 0.0159 | 0.0046 | 0.0524 | 0.0246 | 0.1229 | 0.0476 | 0.1175 | 0.0410 | 0.1431 | 0.0659 | 0.5421 | 0.8134 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0002 | 0.0087 | 0.0013 | 0.0278 | 0.0148 | 0.0578 | 0.0278 | 0.0602 | 0.0168 | 0.0801 | 0.0354 | 0.7618 | 0.9036 | 0.0011 | 0.0118 | 0.0078 | 0.0024 | 0.0111 | 0.0118 | 0.0277 | 0.0729 | 0.0632 | 0.0965 | 0.1164 | 0.1412 | 0.0510 | 0.1529 | 0.0854 | 0.1506 | 0.6364 | 0.3600 | 0.0035 | 0.0025 | 0.0122 | 0.0294 | 0.0704 | 0.1160 | 0.0821 | 0.1013 | 0.5826 | 7 | 9 | 12 | 15 | 24 | 53 | 116 | 205 | 380 | 0.0719 | 21.43 | 4.823 | 0.5539 | 49238.9 | 29200000 | 20700000000 | 16600000000000 | 0.4072 | 0.2209 | 0.0112 | 0.0005 | 0.0637 | 0.0029 | 0.1751 | 0.0280 | 0.2032 | 0.0619 | 0.1751 | 0.1581 | 0.1526 | 0.2116 | 0.1058 | 0.1654 | 0.0702 | 0.1537 | 0.0431 | 0.2180 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0014 | 0.0014 | 0.0111 | 0.0059 | 0.0296 | 0.0273 | 0.0544 | 0.0427 | 0.0464 | 0.0368 | 0.0657 | 0.0505 | 0.7911 | 0.8351 | 0.0010 | 0.0008 | 0.0003 | 0.0006 | 0.0025 | 0.0025 | 0.0113 | 0.0139 | 0.0420 | 0.0541 | 0.0795 | 0.0889 | 0.0566 | 0.0606 | 0.0881 | 0.0878 | 0.7186 | 0.6907 | 0.0004 | 0.0020 | 0.0047 | 0.0105 | 0.0368 | 0.0616 | 0.0504 | 0.0780 | 0.7555 | |||
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 844 | 2908 | 15413 | 16.0 | 5.68 | 6.17 | 2.21 | 10 | 12 | 13 | 14 | 15 | 16 | 18 | 19 | 22 | 0.0804 | 1239 | 1.278 | 24.04 | 7.81 | 0 | 0.0193 | 56 | 0.0081 | 8.98 | 5.211 | 0.3653 | 289.8 | 6020.69 | 146883 | 4220000 | 0.4199 | 0.2102 | 0.0085 | 0.0004 | 0.0216 | 0.0036 | 0.0385 | 0.0085 | 0.0745 | 0.0222 | 0.1137 | 0.0287 | 0.1476 | 0.0534 | 0.2149 | 0.0825 | 0.2097 | 0.1756 | 0.1711 | 0.6250 | 0.0052 | 0.0000 | 0.0124 | 0.0018 | 0.0204 | 0.0040 | 0.0261 | 0.0141 | 0.0461 | 0.0196 | 0.0518 | 0.0236 | 0.0969 | 0.0460 | 0.1330 | 0.0873 | 0.6081 | 0.8036 | 0.0279 | 0.0590 | 0.0540 | 0.0729 | 0.0714 | 0.0521 | 0.0976 | 0.0486 | 0.1063 | 0.0972 | 0.0871 | 0.1632 | 0.1080 | 0.1042 | 0.1307 | 0.1250 | 0.3171 | 0.2778 | 0.0127 | 0.0202 | 0.0254 | 0.0419 | 0.0538 | 0.0695 | 0.1046 | 0.1674 | 0.5045 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0174 | 10.89 | 4.353 | 0.3184 | 42.9 | 326.59 | 2675.72 | 23343.4 | 0.5105 | 0.1490 | 0.0093 | 0.0007 | 0.0467 | 0.0029 | 0.1332 | 0.0168 | 0.2261 | 0.0557 | 0.2649 | 0.1187 | 0.2015 | 0.1957 | 0.0932 | 0.2556 | 0.0225 | 0.2405 | 0.0026 | 0.1134 | 0.0005 | 0.0000 | 0.0014 | 0.0005 | 0.0117 | 0.0029 | 0.0395 | 0.0124 | 0.0975 | 0.0337 | 0.1985 | 0.0723 | 0.2678 | 0.1849 | 0.2578 | 0.3562 | 0.1253 | 0.3371 | 0.1026 | 0.2983 | 0.2437 | 0.3365 | 0.2794 | 0.2278 | 0.2269 | 0.0988 | 0.1028 | 0.0292 | 0.0369 | 0.0090 | 0.0071 | 0.0004 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0196 | 0.0575 | 0.1217 | 0.1919 | 0.2514 | 0.2092 | 0.1174 | 0.0298 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 352 | 145 | 6842 | 23190 | 516.1 | 88.93 | 82.73 | 76.82 | 394 | 442 | 473 | 497 | 519 | 540 | 560 | 588 | 626 | 0.0471 | 1092 | 1.217 | 112.40 | 44.05 | 1 | 0.0417 | 285 | 0.0008 | 51.79 | 7.367 | 0.1654 | 274282.0 | 150000000 | 83800000000 | 48000000000000 | 0.4133 | 0.2357 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0068 | 0.0009 | 0.0395 | 0.0128 | 0.0867 | 0.0244 | 0.0880 | 0.0204 | 0.1257 | 0.0318 | 0.6515 | 0.9098 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0001 | 0.0219 | 0.0112 | 0.0469 | 0.0212 | 0.0429 | 0.0121 | 0.0560 | 0.0240 | 0.8305 | 0.9315 | 0.0064 | 0.0000 | 0.0244 | 0.0385 | 0.0450 | 0.1538 | 0.0720 | 0.1795 | 0.1362 | 0.1538 | 0.1542 | 0.1923 | 0.1105 | 0.1538 | 0.1041 | 0.0769 | 0.3470 | 0.0513 | 0.0006 | 0.0014 | 0.0071 | 0.0246 | 0.0801 | 0.1194 | 0.1251 | 0.1398 | 0.5020 | 13 | 21 | 33 | 47 | 63 | 80 | 100 | 127 | 174 | 0.0136 | 7.65 | 5.221 | 0.4945 | 12746.0 | 3030000 | 998000000 | 416000000000 | 0.4776 | 0.1511 | 0.0127 | 0.0009 | 0.0661 | 0.0029 | 0.1634 | 0.0253 | 0.1896 | 0.0621 | 0.2119 | 0.1354 | 0.1531 | 0.1850 | 0.1031 | 0.1644 | 0.0654 | 0.1703 | 0.0348 | 0.2537 | 0.0006 | 0.0001 | 0.0017 | 0.0006 | 0.0053 | 0.0027 | 0.0178 | 0.0129 | 0.0589 | 0.0423 | 0.0902 | 0.0637 | 0.0775 | 0.0651 | 0.1124 | 0.0898 | 0.6356 | 0.7229 | 0.0024 | 0.0026 | 0.0024 | 0.0051 | 0.0088 | 0.0130 | 0.0336 | 0.0403 | 0.0825 | 0.0987 | 0.1329 | 0.1479 | 0.1037 | 0.1076 | 0.1323 | 0.1377 | 0.5013 | 0.4472 | 0.0009 | 0.0038 | 0.0065 | 0.0246 | 0.0676 | 0.1127 | 0.0949 | 0.1192 | 0.5699 | |||
MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 165 | 346 | 2161 | 4173 | 394.6 | 54.04 | 116.71 | 168.59 | 331 | 354 | 368 | 382 | 402 | 418 | 431 | 442 | 455 | 0.1006 | 420 | 1.034 | 84.17 | 27.73 | 4 | 0.0995 | 215 | 0.0035 | 8.75 | 5.908 | 0.3537 | 158617.0 | 64700000 | 26800000000 | 11200000000000 | 0.4254 | 0.2146 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0025 | 0.0000 | 0.0051 | 0.0028 | 0.0275 | 0.0151 | 0.0499 | 0.0420 | 0.0403 | 0.0193 | 0.0780 | 0.0297 | 0.7961 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0010 | 0.0000 | 0.0025 | 0.0028 | 0.0218 | 0.0151 | 0.0412 | 0.0420 | 0.0233 | 0.0193 | 0.0377 | 0.0297 | 0.8724 | 0.8906 | 0.0962 | 0.0000 | 0.2115 | 0.0000 | 0.2115 | 0.0000 | 0.1346 | 0.0000 | 0.1731 | 0.0000 | 0.0962 | 0.0000 | 0.0577 | 0.0000 | 0.0192 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0034 | 0.0034 | 0.0145 | 0.0298 | 0.0375 | 0.0486 | 0.0520 | 0.8090 | 14 | 17 | 20 | 25 | 38 | 61 | 108 | 180 | 346 | 0.1096 | 12.03 | 4.053 | 0.6346 | 42038.0 | 22900000 | 14900000000 | 10800000000000 | 0.3901 | 0.2553 | 0.0117 | 0.0015 | 0.0731 | 0.0030 | 0.2251 | 0.0345 | 0.1842 | 0.0811 | 0.1754 | 0.1532 | 0.1023 | 0.2387 | 0.0877 | 0.1517 | 0.0614 | 0.1276 | 0.0789 | 0.2087 | 0.0000 | 0.0006 | 0.0015 | 0.0000 | 0.0037 | 0.0019 | 0.0110 | 0.0146 | 0.0389 | 0.0285 | 0.0946 | 0.0856 | 0.0484 | 0.0463 | 0.0748 | 0.0533 | 0.7273 | 0.7692 | 0.0000 | 0.0000 | 0.0029 | 0.0022 | 0.0039 | 0.0011 | 0.0157 | 0.0176 | 0.0695 | 0.0812 | 0.1282 | 0.1405 | 0.0744 | 0.0768 | 0.1018 | 0.1098 | 0.6037 | 0.5708 | 0.0000 | 0.0017 | 0.0042 | 0.0135 | 0.0581 | 0.1053 | 0.0699 | 0.1003 | 0.6470 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 564 | 431 | 338 | 1164 | 102.2 | 15.22 | 7.58 | 3.30 | 84 | 88 | 92 | 95 | 102 | 108 | 112 | 115 | 121 | 0.2259 | 263 | 0.523 | 92.70 | 19.72 | 2 | 0.8195 | 277 | 0.0741 | 0.65 | 2.916 | 0.7228 | 10676.7 | 1140000 | 124000000 | 13800000000 | 0.3677 | 0.2665 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0035 | 0.0000 | 0.0070 | 0.0090 | 0.0662 | 0.0448 | 0.1533 | 0.0985 | 0.0732 | 0.0507 | 0.1150 | 0.0836 | 0.5784 | 0.7134 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0063 | 0.0089 | 0.0508 | 0.0444 | 0.1111 | 0.0947 | 0.0381 | 0.0385 | 0.0730 | 0.0621 | 0.7175 | 0.7515 | 0.0000 | 0.0000 | 0.0357 | 0.0000 | 0.0357 | 1.0000 | 0.1071 | 0.0000 | 0.1786 | 0.0000 | 0.1786 | 0.0000 | 0.1429 | 0.0000 | 0.1071 | 0.0000 | 0.2143 | 0.0000 | 0.0059 | 0.0000 | 0.0000 | 0.0296 | 0.0710 | 0.0888 | 0.0888 | 0.0947 | 0.6213 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1160 | 0.40 | 1.049 | 0.4095 | 68.4 | 808.275 | 13870.1 | 338018 | 0.5218 | 0.1263 | 0.0138 | 0.0000 | 0.1041 | 0.0030 | 0.2004 | 0.0099 | 0.2338 | 0.0338 | 0.1847 | 0.0746 | 0.1493 | 0.1014 | 0.0727 | 0.1690 | 0.0393 | 0.3052 | 0.0020 | 0.3032 | 0.0071 | 0.0000 | 0.0454 | 0.0000 | 0.0894 | 0.0055 | 0.1504 | 0.0193 | 0.1660 | 0.0654 | 0.1943 | 0.1096 | 0.1191 | 0.1436 | 0.1121 | 0.2818 | 0.1163 | 0.3748 | 0.2041 | 0.0875 | 0.1735 | 0.1250 | 0.0561 | 0.1250 | 0.0765 | 0.0500 | 0.1173 | 0.0625 | 0.1276 | 0.1750 | 0.0918 | 0.1625 | 0.0918 | 0.1000 | 0.0612 | 0.1125 | 0.0463 | 0.1305 | 0.1347 | 0.1705 | 0.1347 | 0.1200 | 0.0968 | 0.0758 | 0.0905 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 916 | 643 | 6177 | 7967 | 199.4 | 44.34 | 175.07 | 133.71 | 150 | 163 | 173 | 182 | 192 | 203 | 216 | 234 | 259 | 0.0964 | 768 | 0.994 | 106.57 | 33.42 | 1 | 0.0440 | 272 | 0.0013 | 36.60 | 6.944 | 0.1957 | 41711.5 | 9180000 | 2130000000 | 520000000000 | 0.4243 | 0.2275 | 0.0010 | 0.0000 | 0.0007 | 0.0000 | 0.0032 | 0.0000 | 0.0168 | 0.0009 | 0.0753 | 0.0176 | 0.1308 | 0.0425 | 0.1402 | 0.0375 | 0.1836 | 0.0678 | 0.4482 | 0.8336 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0000 | 0.0076 | 0.0005 | 0.0326 | 0.0112 | 0.0591 | 0.0230 | 0.0595 | 0.0150 | 0.0870 | 0.0231 | 0.7518 | 0.9272 | 0.0009 | 0.0179 | 0.0091 | 0.0358 | 0.0174 | 0.0657 | 0.0659 | 0.1343 | 0.1473 | 0.1433 | 0.1738 | 0.1791 | 0.1363 | 0.0955 | 0.1537 | 0.1164 | 0.2955 | 0.2119 | 0.0011 | 0.0033 | 0.0110 | 0.0375 | 0.0824 | 0.1191 | 0.1085 | 0.1393 | 0.4978 | 30 | 56 | 84 | 112 | 145 | 182 | 223 | 277 | 360 | 0.0025 | 69.87 | 6.927 | 0.2586 | 48522.6 | 17600000 | 7750000000 | 3970000000000 | 0.4873 | 0.1778 | 0.0220 | 0.0017 | 0.1111 | 0.0031 | 0.1870 | 0.0584 | 0.1544 | 0.1117 | 0.1816 | 0.1633 | 0.1457 | 0.1879 | 0.0951 | 0.1507 | 0.0552 | 0.1240 | 0.0479 | 0.1992 | 0.0002 | 0.0004 | 0.0014 | 0.0006 | 0.0029 | 0.0018 | 0.0145 | 0.0127 | 0.0737 | 0.0543 | 0.1090 | 0.0980 | 0.0872 | 0.0692 | 0.1206 | 0.1000 | 0.5904 | 0.6629 | 0.0015 | 0.0034 | 0.0019 | 0.0029 | 0.0087 | 0.0147 | 0.0417 | 0.0563 | 0.1059 | 0.1337 | 0.1647 | 0.1768 | 0.1097 | 0.1254 | 0.1514 | 0.1528 | 0.4144 | 0.3340 | 0.0006 | 0.0033 | 0.0072 | 0.0275 | 0.0899 | 0.1341 | 0.1039 | 0.1338 | 0.4997 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1039 | 381 | 3800 | 9893 | 128.9 | 35.24 | 177.58 | 105.97 | 91 | 99 | 107 | 113 | 121 | 131 | 142 | 156 | 177 | 0.0668 | 661 | 1.078 | 92.18 | 30.89 | 1 | 0.0611 | 232 | 0.0025 | 19.96 | 6.337 | 0.2693 | 17862.2 | 2670000 | 431000000 | 74800000000 | 0.4064 | 0.2310 | 0.0020 | 0.0000 | 0.0049 | 0.0000 | 0.0133 | 0.0003 | 0.0405 | 0.0023 | 0.0968 | 0.0290 | 0.1532 | 0.0582 | 0.1502 | 0.0603 | 0.1789 | 0.0892 | 0.3602 | 0.7607 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0032 | 0.0000 | 0.0142 | 0.0011 | 0.0383 | 0.0165 | 0.0663 | 0.0315 | 0.0670 | 0.0221 | 0.1018 | 0.0464 | 0.7057 | 0.8824 | 0.0013 | 0.0000 | 0.0025 | 0.0150 | 0.0226 | 0.0240 | 0.0477 | 0.1201 | 0.1206 | 0.1592 | 0.1520 | 0.1742 | 0.1244 | 0.1171 | 0.1595 | 0.1411 | 0.3693 | 0.2492 | 0.0019 | 0.0038 | 0.0107 | 0.0239 | 0.0704 | 0.1157 | 0.0855 | 0.1157 | 0.5723 | 56 | 84 | 110 | 137 | 161 | 189 | 217 | 254 | 321 | 0.0018 | 32.40 | 6.743 | 0.2735 | 42762.9 | 12800000 | 4530000000 | 1830000000000 | 0.5224 | 0.1428 | 0.0069 | 0.0004 | 0.0360 | 0.0032 | 0.1033 | 0.0123 | 0.1645 | 0.0379 | 0.1920 | 0.0917 | 0.1882 | 0.1453 | 0.1446 | 0.1523 | 0.1037 | 0.1707 | 0.0608 | 0.3863 | 0.0007 | 0.0000 | 0.0011 | 0.0007 | 0.0051 | 0.0014 | 0.0161 | 0.0074 | 0.0562 | 0.0314 | 0.0904 | 0.0636 | 0.0907 | 0.0624 | 0.1212 | 0.0865 | 0.6186 | 0.7466 | 0.0019 | 0.0053 | 0.0061 | 0.0144 | 0.0200 | 0.0202 | 0.0517 | 0.0554 | 0.0950 | 0.1391 | 0.1363 | 0.1464 | 0.1266 | 0.1165 | 0.1315 | 0.1310 | 0.4309 | 0.3717 | 0.0011 | 0.0046 | 0.0090 | 0.0264 | 0.0790 | 0.1152 | 0.1061 | 0.1299 | 0.5287 |