High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
BT-20 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 137 324 image if available 5641 20747 281.5 64.71 102.70 136.65 202 225 243 262 277 293 311 335 366 0.0556 1153 0.979 115.25 26.87 1 0.0456 257 0.0006 71.66 7.549 0.1440 83449.7
26000000
8510000000
2920000000000
0.4017 0.2486 0.0003 0.0000 0.0006 0.0000 0.0038 0.0000 0.0232 0.0027 0.0713 0.0198 0.1447 0.0392 0.1676 0.0472 0.1783 0.0677 0.4103 0.8235 0.0002 0.0000 0.0002 0.0000 0.0013 0.0000 0.0102 0.0011 0.0291 0.0141 0.0555 0.0255 0.0700 0.0224 0.0851 0.0349 0.7483 0.9020 0.0009 0.0074 0.0085 0.0257 0.0180 0.0662 0.0722 0.1029 0.1472 0.1838 0.1918 0.1618 0.1149 0.1360 0.1434 0.1140 0.3029 0.2022 0.0023 0.0015 0.0072 0.0281 0.0795 0.1228 0.1049 0.1327 0.5209 11 14 17 23 35 63 115 185 286 0.0458 14.71 4.863 0.5260 29220.6
12900000
7580000000
5510000000000
0.5276 0.1342 0.0999 0.0045 0.3282 0.0294 0.3393 0.1714 0.1201 0.2314 0.0597 0.2369 0.0285 0.1756 0.0132 0.0762 0.0090 0.0458 0.0021 0.0287 0.0003 0.0002 0.0004 0.0007 0.0014 0.0014 0.0118 0.0117 0.0724 0.0573 0.1165 0.1003 0.0799 0.0698 0.1094 0.0976 0.6080 0.6610 0.0005 0.0006 0.0012 0.0025 0.0034 0.0047 0.0207 0.0211 0.0878 0.0967 0.1435 0.1663 0.0940 0.0978 0.1317 0.1352 0.5172 0.4752 0.0002 0.0006 0.0024 0.0191 0.0743 0.1338 0.0863 0.1178 0.5656
Hs 578T Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 854 856 image if available 7221 14570 49.4 17.53 78.00 136.28 28 34 38 43 47 52 58 64 73 0.0925 1347 0.564 226.82 39.32 13 0.0867 626 0.0060 6.82 5.419 0.3768 2746.4
169000
11300000
819000000
0.4385 0.1979 0.0021 0.0002 0.0092 0.0013 0.0509 0.0036 0.1206 0.0209 0.1835 0.0519 0.1998 0.1171 0.1729 0.1192 0.1266 0.1517 0.1344 0.5342 0.0004 0.0000 0.0012 0.0005 0.0037 0.0013 0.0217 0.0112 0.0562 0.0266 0.0864 0.0540 0.0848 0.0579 0.1085 0.0691 0.6371 0.7796 0.0039 0.0097 0.0073 0.0154 0.0194 0.0328 0.0682 0.0936 0.1094 0.1380 0.1510 0.1979 0.1292 0.1342 0.1549 0.1467 0.3567 0.2317 0.0017 0.0026 0.0125 0.0408 0.0755 0.1098 0.1078 0.1329 0.5163 11 13 15 17 20 26 46 104 234 0.1860 10.58 3.510 0.6862 24655.2
13200000
8940000000
7000000000000
0.6410 0.1101 0.1548 0.0039 0.3289 0.0394 0.2946 0.2229 0.1131 0.2327 0.0565 0.2189 0.0298 0.1433 0.0134 0.0671 0.0074 0.0493 0.0015 0.0224 0.0008 0.0002 0.0008 0.0005 0.0032 0.0053 0.0201 0.0138 0.0823 0.0766 0.1173 0.0994 0.0839 0.0713 0.1284 0.1266 0.5631 0.6063 0.0003 0.0007 0.0023 0.0021 0.0058 0.0053 0.0229 0.0248 0.1011 0.1076 0.1308 0.1522 0.0995 0.0995 0.1485 0.1501 0.4889 0.4577 0.0000 0.0023 0.0053 0.0197 0.0978 0.1169 0.0934 0.1436 0.5211
BT-20 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 686 761 image if available 4278 10329 575.0 101.74 209.00 348.06 451 485 515 540 564 591 619 660 717 0.0947 978 1.233 88.57 39.70 1 0.0570 244 0.0015 26.90 6.732 0.2213 340946.0
208000000
131000000000
85100000000000
0.4370 0.2089 0.0003 0.0002 0.0016 0.0000 0.0010 0.0000 0.0070 0.0005 0.0491 0.0165 0.1035 0.0326 0.1032 0.0271 0.1478 0.0398 0.5865 0.8833 0.0000 0.0000 0.0008 0.0000 0.0005 0.0000 0.0035 0.0002 0.0289 0.0138 0.0516 0.0248 0.0503 0.0145 0.0751 0.0227 0.7893 0.9239 0.0017 0.0000 0.0017 0.0408 0.0166 0.0510 0.0582 0.1633 0.1481 0.2041 0.1681 0.2245 0.0899 0.0714 0.1514 0.1633 0.3644 0.0816 0.0010 0.0000 0.0051 0.0314 0.0663 0.1352 0.1023 0.1180 0.5408 9 10 12 14 19 49 188 394 707 0.1793 74.24 4.505 0.5801 164813.0
178000000
227000000000
323000000000000
0.5252 0.1228 0.1229 0.0022 0.3301 0.0673 0.2337 0.2076 0.1108 0.1987 0.0723 0.2065 0.0723 0.1358 0.0313 0.0550 0.0193 0.0673 0.0072 0.0595 0.0000 0.0000 0.0009 0.0000 0.0013 0.0020 0.0041 0.0055 0.0525 0.0486 0.0965 0.0858 0.0600 0.0532 0.0839 0.0776 0.7008 0.7272 0.0000 0.0000 0.0000 0.0020 0.0014 0.0012 0.0090 0.0196 0.0690 0.0667 0.1063 0.1181 0.0788 0.0895 0.1095 0.1071 0.6259 0.5958 0.0000 0.0003 0.0000 0.0104 0.0509 0.1031 0.0686 0.0961 0.6707
MCF7 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 533 682 image if available 7313 29998 383.9 96.67 156.93 277.72 269 302 327 350 372 397 429 467 513 0.0399 1198 1.208 132.80 56.82 1 0.0483 353 0.0008 42.70 7.362 0.1796 156719.0
67700000
30900000000
14700000000000
0.4294 0.2186 0.0000 0.0002 0.0019 0.0000 0.0056 0.0006 0.0223 0.0032 0.0776 0.0240 0.1395 0.0531 0.1380 0.0451 0.1584 0.0649 0.4567 0.8089 0.0000 0.0001 0.0011 0.0000 0.0023 0.0003 0.0074 0.0016 0.0342 0.0155 0.0598 0.0314 0.0600 0.0208 0.0798 0.0327 0.7556 0.8977 0.0032 0.0056 0.0051 0.0093 0.0051 0.0075 0.0329 0.0746 0.0981 0.1362 0.1253 0.2034 0.1101 0.1063 0.1380 0.1716 0.4823 0.2854 0.0003 0.0015 0.0075 0.0301 0.0733 0.1004 0.0869 0.1025 0.5975 8 9 11 12 15 25 92 285 569 0.2355 33.94 3.958 0.6313 101753.0
91200000
98600000000
124000000000000
0.4779 0.1557 0.1073 0.0081 0.3320 0.0585 0.3330 0.2590 0.1394 0.2001 0.0471 0.2020 0.0301 0.1388 0.0090 0.0741 0.0020 0.0371 0.0000 0.0223 0.0002 0.0004 0.0006 0.0011 0.0008 0.0010 0.0076 0.0093 0.0425 0.0390 0.0726 0.0654 0.0486 0.0443 0.0803 0.0682 0.7467 0.7711 0.0001 0.0001 0.0004 0.0000 0.0019 0.0013 0.0107 0.0116 0.0477 0.0518 0.0894 0.1012 0.0658 0.0667 0.0972 0.1078 0.6868 0.6595 0.0000 0.0005 0.0009 0.0099 0.0457 0.0788 0.0566 0.0902 0.7173
BT-20 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 355 746 image if available 5178 14618 327.7 65.14 129.72 168.91 250 272 289 304 321 339 359 383 416 0.0483 706 1.223 132.20 48.33 1 0.0624 323 0.0006 79.47 7.577 0.1347 111643.0
39500000
14500000000
5500000000000
0.4016 0.2477 0.0000 0.0000 0.0011 0.0000 0.0020 0.0000 0.0124 0.0010 0.0615 0.0141 0.1154 0.0278 0.1391 0.0377 0.1708 0.0498 0.4976 0.8695 0.0000 0.0000 0.0002 0.0000 0.0009 0.0000 0.0048 0.0006 0.0275 0.0103 0.0562 0.0177 0.0558 0.0168 0.0767 0.0242 0.7779 0.9305 0.0000 0.0057 0.0082 0.0341 0.0411 0.0625 0.0799 0.1591 0.1246 0.1932 0.1669 0.1648 0.1269 0.1193 0.1504 0.1307 0.3020 0.1307 0.0025 0.0038 0.0046 0.0302 0.0772 0.1234 0.1083 0.1318 0.5183 11 13 15 20 32 75 158 264 389 0.0486 32.17 5.262 0.4801 45355.6
21000000
11400000000
6870000000000
0.5030 0.1599 0.1206 0.0006 0.3330 0.0356 0.3146 0.2808 0.1079 0.2475 0.0769 0.1991 0.0321 0.1068 0.0115 0.0595 0.0023 0.0473 0.0011 0.0228 0.0002 0.0000 0.0002 0.0003 0.0019 0.0009 0.0117 0.0095 0.0635 0.0521 0.0928 0.0937 0.0628 0.0577 0.1074 0.0968 0.6595 0.6891 0.0007 0.0007 0.0007 0.0015 0.0029 0.0020 0.0167 0.0162 0.0625 0.0729 0.1186 0.1226 0.0783 0.0896 0.1208 0.1300 0.5988 0.5646 0.0000 0.0002 0.0037 0.0165 0.0591 0.1021 0.0779 0.1118 0.6285
Hs 578T Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 862 60 image if available 536 8372 94.9 38.62 150.81 294.15 38 55 70 85 97 109 121 135 146 0.0688 576 0.456 105.65 21.93 2 0.7705 413 0.0025 45.30 6.078 0.1747 10500.4
1270000
163000000
21700000000
0.3490 0.2577 0.0000 0.0032 0.0057 0.0000 0.0345 0.0000 0.1149 0.0097 0.1782 0.0968 0.1782 0.1452 0.1322 0.1161 0.1379 0.1613 0.2184 0.4677 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0137 0.0024 0.0521 0.0471 0.0493 0.0659 0.0548 0.0329 0.0740 0.0776 0.7562 0.7741 0.0000 0.0000 0.0052 0.0000 0.0052 0.0087 0.0209 0.0435 0.0995 0.1130 0.0785 0.1130 0.1099 0.1217 0.1152 0.1739 0.5654 0.4261 0.0000 0.0000 0.0035 0.0142 0.0745 0.0816 0.0780 0.0957 0.6525 15 18 20 22 25 32 64 197 482 0.1543 30.36 3.816 0.6306 109258.0
124000000
171000000000
266000000000000
0.6017 0.0867 0.1678 0.0032 0.3557 0.0852 0.2550 0.2981 0.1040 0.2618 0.0570 0.1467 0.0336 0.1073 0.0201 0.0442 0.0067 0.0331 0.0000 0.0205 0.0010 0.0004 0.0025 0.0018 0.0029 0.0031 0.0152 0.0161 0.0678 0.0629 0.1130 0.0915 0.0683 0.0683 0.1170 0.1071 0.6123 0.6488 0.0006 0.0006 0.0012 0.0006 0.0069 0.0056 0.0242 0.0311 0.0806 0.0840 0.1163 0.1319 0.0996 0.0989 0.1232 0.1319 0.5475 0.5152 0.0011 0.0021 0.0037 0.0144 0.0880 0.1077 0.0859 0.1189 0.5781
Hs 578T A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 1199 269 image if available 6858 34380 182.5 52.85 124.86 199.10 122 141 154 165 177 190 204 222 256 0.0332 1142 0.787 31.00 8.06 3 0.0117 80 0.0011 37.84 7.176 0.1947 36107.4
7670000
1740000000
418000000000
0.4164 0.2188 0.0008 0.0000 0.0016 0.0003 0.0074 0.0003 0.0251 0.0031 0.0740 0.0238 0.1294 0.0417 0.1524 0.0466 0.1762 0.0732 0.4332 0.8108 0.0004 0.0000 0.0004 0.0000 0.0034 0.0000 0.0103 0.0012 0.0321 0.0128 0.0530 0.0208 0.0614 0.0187 0.0821 0.0317 0.7569 0.9147 0.0035 0.0089 0.0090 0.0089 0.0097 0.0222 0.0520 0.0532 0.0929 0.1064 0.1283 0.1241 0.0999 0.1004 0.1200 0.1241 0.4847 0.4520 0.0016 0.0038 0.0074 0.0272 0.0579 0.0886 0.0908 0.1164 0.6063 17 21 25 29 35 48 91 194 364 0.0577 29.38 4.737 0.5383 55230.0
41200000
40500000000
47700000000000
0.3925 0.2378 0.1380 0.0050 0.3601 0.0465 0.2981 0.2724 0.1080 0.2297 0.0587 0.1914 0.0244 0.1219 0.0089 0.0649 0.0028 0.0419 0.0011 0.0263 0.0001 0.0001 0.0004 0.0005 0.0019 0.0020 0.0186 0.0147 0.0758 0.0670 0.1162 0.0990 0.0798 0.0694 0.1195 0.1071 0.5878 0.6402 0.0002 0.0003 0.0007 0.0022 0.0033 0.0056 0.0256 0.0302 0.0905 0.0964 0.1439 0.1483 0.0934 0.1014 0.1314 0.1378 0.5108 0.4778 0.0002 0.0007 0.0022 0.0238 0.0786 0.1331 0.0854 0.1281 0.5480
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 1069 181 image if available 1596 20629 124.5 28.67 72.87 146.49 98 102 107 111 116 122 130 143 162 0.0438 904 0.809 207.96 60.42 1 0.3440 549 0.0093 6.72 5.134 0.4357 16321.0
2270000
339000000
54100000000
0.4382 0.2050 0.0064 0.0000 0.0064 0.0000 0.0091 0.0000 0.0246 0.0027 0.0665 0.0317 0.0938 0.0661 0.1084 0.0465 0.1321 0.0715 0.5528 0.7815 0.0051 0.0000 0.0044 0.0000 0.0066 0.0000 0.0139 0.0025 0.0285 0.0257 0.0446 0.0426 0.0599 0.0238 0.0833 0.0401 0.7538 0.8653 0.0000 0.0000 0.0037 0.0000 0.0111 0.0000 0.0406 0.0000 0.1144 0.0000 0.1476 0.0000 0.1144 0.0000 0.1255 0.0000 0.4428 0.0000 0.0016 0.0081 0.0049 0.0357 0.0535 0.1086 0.0729 0.1135 0.6013 7 9 11 12 13 15 19 61 281 0.2995 21.07 3.063 0.7088 26767.6
14200000
8950000000
6390000000000
0.3754 0.2426 0.1380 0.0048 0.3646 0.0530 0.2760 0.2133 0.1250 0.2337 0.0781 0.2422 0.0156 0.1627 0.0026 0.0590 0.0000 0.0217 0.0000 0.0096 0.0000 0.0000 0.0002 0.0000 0.0002 0.0005 0.0062 0.0050 0.0345 0.0311 0.0536 0.0493 0.0409 0.0369 0.0551 0.0516 0.8092 0.8256 0.0000 0.0000 0.0000 0.0006 0.0018 0.0030 0.0082 0.0075 0.0356 0.0413 0.0757 0.0865 0.0522 0.0543 0.0707 0.0848 0.7559 0.7221 0.0000 0.0003 0.0008 0.0058 0.0340 0.0678 0.0421 0.0646 0.7846
BT-20 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 179 861 image if available 6894 24993 432.7 77.04 123.09 229.52 337 363 385 406 427 448 470 497 536 0.0541 1352 1.247 106.10 42.20 2 0.0392 270 0.0024 14.62 6.292 0.2830 193164.0
88900000
42200000000
20600000000000
0.4573 0.1908 0.0002 0.0000 0.0008 0.0000 0.0034 0.0000 0.0121 0.0006 0.0472 0.0149 0.0960 0.0253 0.1212 0.0267 0.1545 0.0354 0.5647 0.8972 0.0002 0.0000 0.0003 0.0000 0.0017 0.0000 0.0065 0.0001 0.0253 0.0121 0.0467 0.0177 0.0549 0.0126 0.0783 0.0167 0.7863 0.9408 0.0053 0.0000 0.0160 0.0701 0.0299 0.0764 0.0812 0.1783 0.1335 0.1720 0.1656 0.1783 0.1186 0.1274 0.1346 0.0955 0.3152 0.1019 0.0009 0.0037 0.0079 0.0244 0.0711 0.1200 0.1053 0.1236 0.5430 8 10 12 13 16 23 63 188 422 0.2078 29.75 3.972 0.6370 67827.8
55500000
55600000000
63900000000000
0.4521 0.1694 0.1333 0.0042 0.3651 0.0371 0.3035 0.2123 0.1120 0.2751 0.0504 0.2537 0.0202 0.1124 0.0090 0.0570 0.0045 0.0314 0.0022 0.0167 0.0002 0.0000 0.0002 0.0003 0.0014 0.0008 0.0135 0.0108 0.0527 0.0490 0.0825 0.0789 0.0578 0.0500 0.0808 0.0738 0.7110 0.7365 0.0002 0.0004 0.0009 0.0010 0.0018 0.0029 0.0147 0.0130 0.0575 0.0617 0.0963 0.1072 0.0686 0.0675 0.0945 0.1032 0.6655 0.6432 0.0007 0.0005 0.0013 0.0119 0.0549 0.0931 0.0549 0.0860 0.6968
Hs 578T A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 369 897 image if available 508 2542 168.7 101.76 78.27 159.27 36 52 79 122 170 212 254 284 304 0.1326 337 0.963 124.46 46.23 1 0.6909 351 0.0029 78.06 5.974 0.1808 38792.0
10100000
2760000000
778000000000
0.2699 0.3263 0.0000 0.0000 0.0278 0.0000 0.2917 0.0000 0.3889 0.0065 0.1528 0.1883 0.0556 0.3701 0.0556 0.2013 0.0278 0.0909 0.0000 0.1429 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0104 0.0000 0.0519 0.0604 0.0900 0.0876 0.0484 0.0363 0.0727 0.0695 0.7266 0.7462 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0092 0.0113 0.0553 0.0791 0.1244 0.1017 0.0369 0.0508 0.0691 0.0904 0.7051 0.6667 0.0000 0.0000 0.0039 0.0039 0.0547 0.1094 0.0352 0.0742 0.7188 14 16 18 20 22 28 42 75 198 0.0967 17.71 3.564 0.6230 31483.0
24000000
22900000000
24100000000000
0.5318 0.1158 0.1119 0.0000 0.3731 0.0552 0.2836 0.1595 0.0970 0.2209 0.0672 0.2331 0.0299 0.1626 0.0299 0.0890 0.0075 0.0491 0.0000 0.0307 0.0000 0.0000 0.0035 0.0014 0.0086 0.0043 0.0276 0.0340 0.1261 0.1007 0.1572 0.1277 0.0950 0.0879 0.1295 0.1433 0.4525 0.5007 0.0000 0.0026 0.0112 0.0026 0.0067 0.0211 0.0315 0.0554 0.1393 0.1135 0.1685 0.1821 0.0921 0.1055 0.1573 0.1293 0.3933 0.3879 0.0000 0.0040 0.0140 0.0460 0.1180 0.1560 0.0960 0.1540 0.4120
Hs 578T Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 903 431 image if available 54613 82874 84.8 46.65 114.00 205.41 23 28 54 73 87 99 112 126 146 0.0303 2514 0.607 231.82 52.47 24 0.0118 645 0.0046 13.65 6.351 0.3627 9367.0
1190000
165000000
24700000000
0.5125 0.1476 0.0017 0.0007 0.0076 0.0010 0.0380 0.0040 0.0801 0.0150 0.1435 0.0575 0.1828 0.1084 0.1675 0.1062 0.1626 0.1362 0.2163 0.5709 0.0002 0.0000 0.0004 0.0000 0.0014 0.0002 0.0055 0.0015 0.0213 0.0119 0.0388 0.0234 0.0374 0.0198 0.0551 0.0316 0.8399 0.9117 0.0006 0.0018 0.0028 0.0048 0.0065 0.0130 0.0229 0.0391 0.0576 0.0808 0.0882 0.1189 0.0857 0.0985 0.1117 0.1228 0.6241 0.5203 0.0004 0.0014 0.0040 0.0124 0.0339 0.0605 0.0589 0.0824 0.7461 10 12 13 15 18 26 61 174 383 0.2390 19.16 3.787 0.6638 55186.4
40400000
36400000000
37700000000000
0.4605 0.1949 0.1576 0.0035 0.3814 0.0611 0.3071 0.3277 0.0839 0.2234 0.0408 0.1726 0.0158 0.1086 0.0071 0.0487 0.0039 0.0298 0.0026 0.0245 0.0001 0.0001 0.0006 0.0003 0.0013 0.0008 0.0117 0.0106 0.0652 0.0602 0.1027 0.0939 0.0640 0.0575 0.0983 0.0881 0.6561 0.6885 0.0000 0.0004 0.0009 0.0009 0.0020 0.0025 0.0164 0.0184 0.0742 0.0778 0.1173 0.1225 0.0764 0.0817 0.1085 0.1098 0.6044 0.5860 0.0001 0.0002 0.0017 0.0132 0.0722 0.1105 0.0693 0.1056 0.6272
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 164 879 image if available 4050 8872 419.4 110.73 86.10 234.18 295 334 362 385 409 439 474 515 570 0.0979 869 0.960 155.00 54.01 3 0.1049 425 0.0007 76.29 7.489 0.1602 188142.0
89200000
44400000000
23100000000000
0.4137 0.2255 0.0004 0.0000 0.0017 0.0000 0.0052 0.0000 0.0231 0.0043 0.0718 0.0210 0.1144 0.0459 0.1271 0.0397 0.1462 0.0559 0.5100 0.8333 0.0003 0.0000 0.0006 0.0000 0.0019 0.0000 0.0071 0.0013 0.0298 0.0149 0.0481 0.0238 0.0528 0.0149 0.0708 0.0245 0.7886 0.9206 0.0011 0.0000 0.0043 0.0099 0.0130 0.0099 0.0444 0.0759 0.0704 0.1452 0.1083 0.1716 0.0986 0.1089 0.1073 0.1584 0.5525 0.3201 0.0016 0.0032 0.0111 0.0185 0.0506 0.0749 0.0611 0.0870 0.6921 11 12 14 15 16 17 20 35 226 0.4982 14.49 2.220 0.8059 62249.3
81200000
135000000000
258000000000000
0.6303 0.0763 0.2131 0.0132 0.4262 0.1376 0.2295 0.3995 0.0546 0.1508 0.0546 0.1164 0.0219 0.1085 0.0000 0.0423 0.0000 0.0265 0.0000 0.0053 0.0007 0.0006 0.0055 0.0019 0.0097 0.0070 0.0194 0.0171 0.0947 0.0912 0.1418 0.1476 0.0705 0.0646 0.0961 0.0956 0.5615 0.5744 0.0008 0.0008 0.0032 0.0042 0.0071 0.0100 0.0301 0.0308 0.1013 0.1032 0.1362 0.1424 0.0831 0.0849 0.1077 0.1091 0.5305 0.5146 0.0022 0.0037 0.0066 0.0176 0.1051 0.1412 0.0713 0.1037 0.5485
MCF 10A Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 1243 854 image if available 722 7966 63.7 17.26 99.18 192.37 47 51 53 56 60 63 68 74 85 0.0734 585 0.421 183.11 37.80 0 0.8726 630 0.0093 10.56 5.018 0.3434 4360.7
324711
26600000
2420000000
0.4665 0.1732 0.0048 0.0000 0.0238 0.0000 0.0499 0.0060 0.0950 0.0255 0.1354 0.0510 0.1853 0.0990 0.1663 0.1049 0.1663 0.1094 0.1734 0.6042 0.0000 0.0000 0.0073 0.0000 0.0128 0.0028 0.0475 0.0097 0.0786 0.0444 0.1408 0.0819 0.1261 0.0611 0.1481 0.0833 0.4388 0.7167 0.0000 0.0000 0.0317 0.0377 0.0159 0.0755 0.0952 0.0755 0.1825 0.3019 0.1825 0.1321 0.1508 0.0566 0.1508 0.2075 0.1905 0.1132 0.0036 0.0180 0.0288 0.0791 0.1259 0.1691 0.1295 0.1511 0.2950 10 12 14 15 17 19 31 113 371 0.1151 73.14 4.084 0.5429 46837.2
32700000
27500000000
26300000000000
0.6007 0.1115 0.2664 0.0211 0.4953 0.1607 0.2103 0.5011 0.0280 0.1882 0.0000 0.0782 0.0000 0.0338 0.0000 0.0127 0.0000 0.0042 0.0000 0.0000 0.0006 0.0005 0.0022 0.0015 0.0056 0.0036 0.0185 0.0247 0.0888 0.0781 0.1355 0.1183 0.0748 0.0848 0.1231 0.1177 0.5509 0.5707 0.0006 0.0007 0.0013 0.0041 0.0083 0.0082 0.0230 0.0211 0.0856 0.0958 0.1540 0.1501 0.0818 0.0795 0.1176 0.1291 0.5278 0.5115 0.0012 0.0024 0.0054 0.0198 0.0929 0.1360 0.0827 0.1210 0.5386
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1130 460 image if available 653 578 83.3 9.22 65.56 101.38 71 74 78 80 83 86 89 92 95 0.3910 226 0.478 77.79 11.31 1 0.3155 206 0.1159 0.55 2.394 0.7678 7017.7
598559
51600000
4510000000
0.4222 0.2132 0.0000 0.0000 0.0000 0.0000 0.0032 0.0000 0.0065 0.0015 0.0455 0.0352 0.0698 0.0674 0.0779 0.0260 0.1347 0.0475 0.6623 0.8224 0.0000 0.0000 0.0000 0.0000 0.0031 0.0000 0.0047 0.0015 0.0376 0.0352 0.0610 0.0674 0.0297 0.0260 0.0563 0.0475 0.8075 0.8224 0.1304 0.0000 0.3478 0.0000 0.2174 0.0000 0.1304 0.0000 0.0870 0.0000 0.0435 0.0000 0.0435 0.0000 0.0000 0.0000 0.0000 0.0000 0.0030 0.0151 0.0211 0.0452 0.0994 0.0964 0.1325 0.1687 0.4187 7 10 13 18 24 35 52 90 200 0.0809 31.27 3.431 0.5091 14559.2
5410000
2520000000
1320000000000
0.5610 0.0846 0.2727 0.0094 0.5000 0.0377 0.2273 0.4151 0.0000 0.3396 0.0000 0.1038 0.0000 0.0849 0.0000 0.0094 0.0000 0.0000 0.0000 0.0000 0.0000 0.0046 0.0405 0.0091 0.0173 0.0274 0.0347 0.0365 0.2023 0.1507 0.3410 0.3196 0.1676 0.1553 0.1850 0.1918 0.0116 0.1050 0.0155 0.0177 0.0233 0.0265 0.0698 0.0885 0.0853 0.0619 0.2636 0.3894 0.3488 0.3009 0.1860 0.1150 0.0078 0.0000 0.0000 0.0000 0.0134 0.0201 0.0336 0.0336 0.2282 0.3758 0.2013 0.0940 0.0000