High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 404 | 381 | 364 | 11109 | 91.1 | 12.14 | 8.23 | 2.31 | 76 | 80 | 84 | 87 | 91 | 94 | 97 | 101 | 107 | 0.0564 | 627 | 0.370 | 126.83 | 26.31 | 1 | 1.2060 | 439 | 0.0718 | 0.71 | 2.815 | 0.7088 | 8437.9 | 795470 | 76300000 | 7430000000 | 0.3908 | 0.2100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0192 | 0.0055 | 0.0895 | 0.0714 | 0.1789 | 0.1099 | 0.1278 | 0.0604 | 0.1917 | 0.1044 | 0.3930 | 0.6484 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0117 | 0.0055 | 0.0787 | 0.0714 | 0.1254 | 0.1099 | 0.0671 | 0.0604 | 0.1195 | 0.1044 | 0.5977 | 0.6484 | 0.0333 | 0.0000 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.1333 | 0.0000 | 0.2000 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.0055 | 0.0055 | 0.0055 | 0.0546 | 0.1421 | 0.1694 | 0.1038 | 0.1639 | 0.3497 | 5 | 6 | 7 | 8 | 8 | 9 | 9 | 10 | 11 | 0.2651 | 0.45 | 1.038 | 0.6298 | 73.1 | 692.301 | 6934.55 | 73026.4 | 0.5150 | 0.1470 | 0.0084 | 0.0000 | 0.0454 | 0.0006 | 0.1209 | 0.0027 | 0.2055 | 0.0101 | 0.2489 | 0.0293 | 0.2133 | 0.0743 | 0.1150 | 0.1788 | 0.0368 | 0.3510 | 0.0059 | 0.3532 | 0.0002 | 0.0000 | 0.0024 | 0.0000 | 0.0090 | 0.0002 | 0.0345 | 0.0025 | 0.0902 | 0.0128 | 0.1613 | 0.0328 | 0.2251 | 0.0673 | 0.2757 | 0.2320 | 0.2014 | 0.6524 | 0.0871 | 0.3913 | 0.1762 | 0.3337 | 0.2103 | 0.1554 | 0.1847 | 0.0633 | 0.1500 | 0.0368 | 0.1089 | 0.0161 | 0.0537 | 0.0035 | 0.0237 | 0.0000 | 0.0054 | 0.0000 | 0.0034 | 0.0150 | 0.0465 | 0.1072 | 0.1765 | 0.2248 | 0.1975 | 0.1520 | 0.0770 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 688 | 317 | 634 | 1912 | 61.1 | 11.51 | 6.65 | 2.29 | 51 | 53 | 55 | 57 | 59 | 62 | 64 | 67 | 72 | 0.1815 | 347 | 0.352 | 32.70 | 5.39 | 1 | 0.1893 | 120 | 0.1030 | 0.83 | 2.651 | 0.7146 | 3861.0 | 255798 | 18100000 | 1380000000 | 0.3514 | 0.2723 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0147 | 0.0049 | 0.0257 | 0.0180 | 0.0754 | 0.0377 | 0.1471 | 0.1361 | 0.0901 | 0.0656 | 0.1746 | 0.0885 | 0.4669 | 0.6492 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0117 | 0.0016 | 0.0167 | 0.0126 | 0.0552 | 0.0379 | 0.1154 | 0.1183 | 0.0635 | 0.0473 | 0.1338 | 0.0804 | 0.6020 | 0.7019 | 0.0185 | 0.0000 | 0.0000 | 0.0000 | 0.1111 | 0.0000 | 0.0741 | 0.2500 | 0.1852 | 0.1667 | 0.1852 | 0.3333 | 0.1111 | 0.0000 | 0.0741 | 0.0833 | 0.2407 | 0.1667 | 0.0071 | 0.0179 | 0.0214 | 0.0750 | 0.1571 | 0.1607 | 0.1750 | 0.1321 | 0.2536 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.0192 | 7.74 | 4.309 | 0.3727 | 49.5 | 405.119 | 3603.71 | 34564.2 | 0.5192 | 0.1236 | 0.0276 | 0.0014 | 0.1166 | 0.0113 | 0.1899 | 0.0346 | 0.2067 | 0.0720 | 0.2067 | 0.1200 | 0.1322 | 0.1962 | 0.0745 | 0.2392 | 0.0397 | 0.2188 | 0.0060 | 0.1066 | 0.0107 | 0.0006 | 0.0471 | 0.0074 | 0.0661 | 0.0135 | 0.1033 | 0.0418 | 0.1281 | 0.0811 | 0.1702 | 0.1345 | 0.1860 | 0.1499 | 0.1570 | 0.2500 | 0.1314 | 0.3213 | 0.1296 | 0.2038 | 0.1640 | 0.2464 | 0.2275 | 0.2512 | 0.1772 | 0.1706 | 0.1296 | 0.0569 | 0.1032 | 0.0474 | 0.0423 | 0.0237 | 0.0265 | 0.0000 | 0.0000 | 0.0000 | 0.0322 | 0.0665 | 0.1104 | 0.1179 | 0.1533 | 0.1608 | 0.1554 | 0.1222 | 0.0815 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1052 | 237 | 1244 | 2214 | 114.3 | 23.44 | 7.50 | 2.80 | 84 | 94 | 100 | 107 | 113 | 120 | 127 | 134 | 145 | 0.1920 | 425 | 1.281 | 34.41 | 15.23 | 1 | 0.0748 | 93 | 0.0239 | 1.48 | 4.012 | 0.6161 | 13623.0 | 1690000 | 216000000 | 28600000000 | 0.3972 | 0.2379 | 0.0012 | 0.0000 | 0.0000 | 0.0008 | 0.0075 | 0.0034 | 0.0187 | 0.0034 | 0.0748 | 0.0322 | 0.1097 | 0.0593 | 0.1222 | 0.0364 | 0.1534 | 0.0653 | 0.5125 | 0.7992 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0008 | 0.0088 | 0.0024 | 0.0362 | 0.0276 | 0.0480 | 0.0487 | 0.0490 | 0.0244 | 0.0803 | 0.0414 | 0.7747 | 0.8547 | 0.0000 | 0.0192 | 0.0183 | 0.0000 | 0.0137 | 0.0577 | 0.0822 | 0.0769 | 0.1187 | 0.1538 | 0.1187 | 0.1538 | 0.1187 | 0.1154 | 0.1461 | 0.2692 | 0.3836 | 0.1538 | 0.0016 | 0.0049 | 0.0098 | 0.0276 | 0.0683 | 0.0862 | 0.0992 | 0.1382 | 0.5642 | 4 | 5 | 6 | 6 | 8 | 8 | 9 | 10 | 11 | 0.0155 | 11.39 | 4.516 | 0.3088 | 64.1 | 606.433 | 6239.84 | 68969.9 | 0.5222 | 0.1520 | 0.0555 | 0.0000 | 0.1778 | 0.0044 | 0.2383 | 0.0172 | 0.2497 | 0.0498 | 0.1728 | 0.1007 | 0.0757 | 0.1638 | 0.0240 | 0.1970 | 0.0063 | 0.2601 | 0.0000 | 0.2070 | 0.0182 | 0.0000 | 0.0507 | 0.0020 | 0.0954 | 0.0096 | 0.1105 | 0.0359 | 0.1294 | 0.0759 | 0.1658 | 0.1128 | 0.1400 | 0.1224 | 0.1726 | 0.2124 | 0.1173 | 0.4289 | 0.1080 | 0.3059 | 0.1667 | 0.1588 | 0.1212 | 0.2059 | 0.1477 | 0.1294 | 0.1496 | 0.1412 | 0.1591 | 0.0353 | 0.1080 | 0.0176 | 0.0265 | 0.0059 | 0.0133 | 0.0000 | 0.0367 | 0.0752 | 0.1235 | 0.1074 | 0.1406 | 0.1352 | 0.1227 | 0.1513 | 0.1074 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 644 | 300 | 381 | 806 | 12.1 | 3.51 | 5.40 | 1.98 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 17 | 0.3623 | 292 | 0.804 | 32.02 | 8.25 | 0 | 0.2283 | 87 | 0.0100 | 11.54 | 4.797 | 0.2819 | 158.7 | 2234.75 | 33514.1 | 530731 | 0.4187 | 0.2080 | 0.0000 | 0.0000 | 0.0459 | 0.0000 | 0.1429 | 0.0033 | 0.1837 | 0.0262 | 0.2143 | 0.1082 | 0.2245 | 0.1934 | 0.1071 | 0.1836 | 0.0663 | 0.2787 | 0.0153 | 0.2066 | 0.0000 | 0.0000 | 0.0179 | 0.0000 | 0.0286 | 0.0000 | 0.0536 | 0.0143 | 0.0929 | 0.0602 | 0.1071 | 0.0659 | 0.1464 | 0.1347 | 0.1929 | 0.2063 | 0.3607 | 0.5186 | 0.0238 | 0.0682 | 0.1310 | 0.2045 | 0.1310 | 0.1136 | 0.2262 | 0.1591 | 0.1667 | 0.1364 | 0.1548 | 0.2273 | 0.0595 | 0.0455 | 0.0833 | 0.0455 | 0.0238 | 0.0000 | 0.0094 | 0.0330 | 0.0377 | 0.0566 | 0.1226 | 0.1509 | 0.1462 | 0.2217 | 0.2217 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0262 | 8.53 | 4.026 | 0.3635 | 33.1 | 222.937 | 1630.58 | 12844 | 0.5218 | 0.1301 | 0.0340 | 0.0037 | 0.1671 | 0.0201 | 0.2125 | 0.0713 | 0.2351 | 0.1755 | 0.2153 | 0.2194 | 0.0963 | 0.2102 | 0.0397 | 0.1481 | 0.0000 | 0.1097 | 0.0000 | 0.0420 | 0.0014 | 0.0013 | 0.0029 | 0.0000 | 0.0203 | 0.0053 | 0.0695 | 0.0420 | 0.1462 | 0.1183 | 0.1650 | 0.1367 | 0.1838 | 0.1380 | 0.2489 | 0.2076 | 0.1621 | 0.3509 | 0.0355 | 0.1308 | 0.1450 | 0.2664 | 0.2367 | 0.2617 | 0.2426 | 0.1215 | 0.1538 | 0.1308 | 0.0947 | 0.0607 | 0.0562 | 0.0187 | 0.0266 | 0.0000 | 0.0089 | 0.0093 | 0.0018 | 0.0235 | 0.0868 | 0.1374 | 0.1953 | 0.2441 | 0.2080 | 0.0759 | 0.0271 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 897 | 352 | 491 | 10165 | 31.2 | 10.66 | 5.57 | 2.04 | 21 | 23 | 24 | 26 | 27 | 30 | 34 | 40 | 49 | 0.0858 | 872 | 0.813 | 87.21 | 20.59 | 5 | 0.4073 | 200 | 0.0618 | 0.76 | 3.150 | 0.6872 | 1083.9 | 42132.6 | 1810000 | 83600000 | 0.3481 | 0.2731 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0187 | 0.0025 | 0.0561 | 0.0150 | 0.1168 | 0.0848 | 0.2336 | 0.0798 | 0.1963 | 0.0873 | 0.1869 | 0.1446 | 0.1729 | 0.5860 | 0.0061 | 0.0000 | 0.0061 | 0.0000 | 0.0122 | 0.0021 | 0.0334 | 0.0125 | 0.0608 | 0.0582 | 0.0912 | 0.0353 | 0.0821 | 0.0561 | 0.1003 | 0.0811 | 0.6079 | 0.7547 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0348 | 0.0625 | 0.0609 | 0.0500 | 0.1391 | 0.1625 | 0.0609 | 0.1125 | 0.1043 | 0.0750 | 0.6000 | 0.5375 | 0.0000 | 0.0107 | 0.0000 | 0.0481 | 0.0428 | 0.1070 | 0.0695 | 0.1016 | 0.6203 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0061 | 0.11 | 0.381 | 0.0699 | 35.2 | 247.481 | 1925.98 | 16644.2 | 0.5163 | 0.1494 | 0.0075 | 0.0004 | 0.0317 | 0.0014 | 0.1096 | 0.0083 | 0.1889 | 0.0233 | 0.2557 | 0.0515 | 0.2310 | 0.1180 | 0.1247 | 0.2326 | 0.0447 | 0.3477 | 0.0060 | 0.2168 | 0.0016 | 0.0000 | 0.0075 | 0.0002 | 0.0348 | 0.0045 | 0.0908 | 0.0154 | 0.1571 | 0.0325 | 0.2323 | 0.0692 | 0.2275 | 0.1499 | 0.1597 | 0.3269 | 0.0887 | 0.4014 | 0.2469 | 0.4372 | 0.2984 | 0.2271 | 0.1850 | 0.0804 | 0.0888 | 0.0635 | 0.0564 | 0.0536 | 0.0355 | 0.0409 | 0.0392 | 0.0381 | 0.0282 | 0.0381 | 0.0214 | 0.0212 | 0.0197 | 0.0760 | 0.1532 | 0.2101 | 0.1844 | 0.1602 | 0.1001 | 0.0600 | 0.0363 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 214 | 329 | 2935 | 11303 | 279.9 | 61.40 | 6.40 | 2.56 | 193 | 217 | 240 | 262 | 283 | 300 | 320 | 339 | 363 | 0.0572 | 646 | 0.707 | 220.60 | 68.41 | 1 | 0.2290 | 672 | 0.0038 | 5.82 | 5.792 | 0.3874 | 82100.6 | 25100000 | 7920000000 | 2580000000000 | 0.3742 | 0.2640 | 0.0012 | 0.0000 | 0.0055 | 0.0000 | 0.0068 | 0.0003 | 0.0197 | 0.0035 | 0.0419 | 0.0219 | 0.0653 | 0.0299 | 0.0635 | 0.0285 | 0.1054 | 0.0597 | 0.6907 | 0.8563 | 0.0009 | 0.0000 | 0.0018 | 0.0000 | 0.0013 | 0.0003 | 0.0075 | 0.0027 | 0.0168 | 0.0196 | 0.0266 | 0.0240 | 0.0239 | 0.0192 | 0.0350 | 0.0343 | 0.8862 | 0.8998 | 0.0031 | 0.1875 | 0.0126 | 0.2813 | 0.0173 | 0.3750 | 0.0346 | 0.0938 | 0.0456 | 0.0625 | 0.0566 | 0.0000 | 0.0629 | 0.0000 | 0.0849 | 0.0000 | 0.6824 | 0.0000 | 0.0013 | 0.0020 | 0.0059 | 0.0092 | 0.0277 | 0.0323 | 0.0323 | 0.0554 | 0.8339 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 0.4396 | 0.38 | 1.169 | 0.8081 | 47.5 | 391.249 | 3512.14 | 33881.8 | 0.4867 | 0.1660 | 0.0087 | 0.0004 | 0.0533 | 0.0075 | 0.1339 | 0.0348 | 0.2382 | 0.1039 | 0.2579 | 0.1830 | 0.1883 | 0.2424 | 0.0921 | 0.2426 | 0.0230 | 0.1419 | 0.0046 | 0.0434 | 0.0002 | 0.0000 | 0.0018 | 0.0009 | 0.0097 | 0.0035 | 0.0393 | 0.0162 | 0.0799 | 0.0427 | 0.1426 | 0.0876 | 0.2155 | 0.1902 | 0.2757 | 0.3292 | 0.2352 | 0.3297 | 0.0810 | 0.1861 | 0.1648 | 0.2753 | 0.2049 | 0.2537 | 0.1900 | 0.1433 | 0.1511 | 0.0792 | 0.1073 | 0.0385 | 0.0628 | 0.0186 | 0.0300 | 0.0043 | 0.0081 | 0.0009 | 0.0035 | 0.0243 | 0.0659 | 0.1244 | 0.1728 | 0.2058 | 0.2030 | 0.1370 | 0.0633 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1026 | 526 | 1774 | 10377 | 333.7 | 82.77 | 7.07 | 6.95 | 228 | 252 | 275 | 299 | 328 | 356 | 381 | 404 | 456 | 0.0754 | 782 | 1.019 | 63.03 | 17.72 | 1 | 0.0902 | 160 | 0.0074 | 2.20 | 5.116 | 0.5219 | 118176.0 | 44200000 | 17400000000 | 7100000000000 | 0.3704 | 0.2523 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0044 | 0.0018 | 0.0196 | 0.0031 | 0.0480 | 0.0270 | 0.0981 | 0.0590 | 0.0960 | 0.0277 | 0.1156 | 0.0522 | 0.6161 | 0.8291 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0006 | 0.0077 | 0.0006 | 0.0216 | 0.0198 | 0.0448 | 0.0475 | 0.0309 | 0.0158 | 0.0394 | 0.0300 | 0.8533 | 0.8858 | 0.0000 | 0.0070 | 0.0026 | 0.0000 | 0.0159 | 0.0211 | 0.0265 | 0.0493 | 0.0688 | 0.0563 | 0.0688 | 0.0634 | 0.0794 | 0.1197 | 0.0926 | 0.1127 | 0.6455 | 0.5704 | 0.0000 | 0.0012 | 0.0035 | 0.0106 | 0.0307 | 0.0507 | 0.0460 | 0.0507 | 0.8066 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.0683 | 0.36 | 0.960 | 0.2803 | 98.4 | 3645.61 | 211535 | 13700000 | 0.5870 | 0.1077 | 0.0219 | 0.0000 | 0.0918 | 0.0034 | 0.2036 | 0.0218 | 0.2478 | 0.0615 | 0.2315 | 0.1441 | 0.1344 | 0.2346 | 0.0524 | 0.2632 | 0.0151 | 0.1992 | 0.0014 | 0.0723 | 0.0070 | 0.0001 | 0.0372 | 0.0017 | 0.1009 | 0.0115 | 0.1433 | 0.0351 | 0.1866 | 0.1006 | 0.1797 | 0.1701 | 0.1357 | 0.2256 | 0.0991 | 0.2326 | 0.1105 | 0.2226 | 0.2165 | 0.2377 | 0.1957 | 0.1575 | 0.1447 | 0.1137 | 0.0919 | 0.0699 | 0.0705 | 0.0657 | 0.0566 | 0.0428 | 0.0334 | 0.0323 | 0.0340 | 0.0396 | 0.1567 | 0.2409 | 0.0252 | 0.0972 | 0.1538 | 0.1674 | 0.1709 | 0.1299 | 0.1019 | 0.0664 | 0.0874 | |
SK-BR-3 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 961 | 83 | 2742 | 10295 | 256.4 | 210.99 | 5.84 | 2.73 | 85 | 107 | 125 | 146 | 174 | 205 | 260 | 375 | 620 | 0.0768 | 791 | 0.892 | 36.22 | 8.60 | 0 | 0.0317 | 87 | 0.0014 | 48.21 | 6.944 | 0.2535 | 110231.0 | 65700000 | 45700000000 | 34200000000000 | 0.3023 | 0.3121 | 0.0000 | 0.0000 | 0.0068 | 0.0000 | 0.0091 | 0.0000 | 0.0590 | 0.0149 | 0.1791 | 0.0528 | 0.1655 | 0.0916 | 0.1179 | 0.0677 | 0.1088 | 0.1066 | 0.3537 | 0.6663 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0076 | 0.0370 | 0.0242 | 0.0497 | 0.0369 | 0.0416 | 0.0242 | 0.0542 | 0.0445 | 0.8076 | 0.8626 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0075 | 0.0070 | 0.0330 | 0.0370 | 0.0526 | 0.0546 | 0.0330 | 0.0352 | 0.0691 | 0.0651 | 0.8018 | 0.8011 | 0.0012 | 0.0012 | 0.0000 | 0.0059 | 0.0297 | 0.0547 | 0.0321 | 0.0523 | 0.8228 | 2 | 4 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 0.0175 | 13.89 | 4.460 | 0.2950 | 41.5 | 339.783 | 3128.09 | 31961.6 | 0.5476 | 0.1416 | 0.0210 | 0.0022 | 0.0924 | 0.0062 | 0.1853 | 0.0333 | 0.2319 | 0.0823 | 0.2233 | 0.1544 | 0.1561 | 0.2425 | 0.0700 | 0.2497 | 0.0170 | 0.1701 | 0.0030 | 0.0593 | 0.0012 | 0.0000 | 0.0080 | 0.0010 | 0.0371 | 0.0068 | 0.0981 | 0.0266 | 0.1836 | 0.0573 | 0.2370 | 0.1201 | 0.2176 | 0.2178 | 0.1428 | 0.3119 | 0.0746 | 0.2586 | 0.1311 | 0.2667 | 0.2100 | 0.2515 | 0.2092 | 0.1673 | 0.1698 | 0.1115 | 0.1054 | 0.0630 | 0.0671 | 0.0527 | 0.0519 | 0.0333 | 0.0371 | 0.0339 | 0.0183 | 0.0200 | 0.0124 | 0.0502 | 0.1000 | 0.1483 | 0.1892 | 0.1839 | 0.1558 | 0.0989 | 0.0613 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 613 | 713 | 713 | 1229 | 91.3 | 14.01 | 6.39 | 2.54 | 72 | 77 | 83 | 87 | 92 | 96 | 100 | 104 | 109 | 0.2522 | 310 | 1.070 | 24.52 | 7.28 | 1 | 0.0884 | 63 | 0.0680 | 0.69 | 2.897 | 0.7227 | 8522.9 | 813628 | 79300000 | 7870000000 | 0.3848 | 0.2534 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0123 | 0.0014 | 0.0247 | 0.0014 | 0.0670 | 0.0492 | 0.0917 | 0.0646 | 0.1217 | 0.0478 | 0.1711 | 0.0772 | 0.5062 | 0.7584 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0095 | 0.0014 | 0.0127 | 0.0014 | 0.0523 | 0.0491 | 0.0507 | 0.0645 | 0.0555 | 0.0477 | 0.0777 | 0.0659 | 0.7369 | 0.7700 | 0.0156 | 1.0000 | 0.0938 | 0.0000 | 0.0625 | 0.0000 | 0.1406 | 0.0000 | 0.2344 | 0.0000 | 0.1875 | 0.0000 | 0.0781 | 0.0000 | 0.1094 | 0.0000 | 0.0781 | 0.0000 | 0.0053 | 0.0107 | 0.0213 | 0.0373 | 0.0613 | 0.0587 | 0.0827 | 0.1280 | 0.5947 | 3 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0448 | 0.26 | 0.778 | 0.2347 | 47.3 | 411.762 | 4361.59 | 56996.9 | 0.5177 | 0.1432 | 0.0094 | 0.0021 | 0.0336 | 0.0064 | 0.0983 | 0.0364 | 0.1023 | 0.0621 | 0.1911 | 0.1424 | 0.2248 | 0.1681 | 0.1736 | 0.2141 | 0.1279 | 0.2473 | 0.0390 | 0.1210 | 0.0000 | 0.0000 | 0.0048 | 0.0009 | 0.0183 | 0.0109 | 0.0502 | 0.0263 | 0.1187 | 0.1069 | 0.1525 | 0.1295 | 0.2008 | 0.1639 | 0.2346 | 0.2473 | 0.2201 | 0.3143 | 0.1365 | 0.2588 | 0.2048 | 0.1882 | 0.1468 | 0.1353 | 0.1433 | 0.1353 | 0.1502 | 0.0588 | 0.0785 | 0.0471 | 0.0512 | 0.0529 | 0.0375 | 0.0412 | 0.0512 | 0.0824 | 0.0038 | 0.0368 | 0.0722 | 0.1293 | 0.1812 | 0.1787 | 0.1496 | 0.1546 | 0.0938 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1218 | 127 | 498 | 20452 | 136.6 | 11.03 | 9.21 | 3.44 | 125 | 129 | 132 | 134 | 137 | 139 | 142 | 145 | 150 | 0.0417 | 853 | 1.250 | 19.42 | 8.06 | 3 | 0.1104 | 55 | 0.0920 | 0.84 | 2.707 | 0.6980 | 18782.2 | 2600000 | 362000000 | 50600000000 | 0.4730 | 0.1733 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0103 | 0.0080 | 0.0103 | 0.0080 | 0.0514 | 0.0502 | 0.1337 | 0.1285 | 0.0638 | 0.0582 | 0.1008 | 0.0683 | 0.6276 | 0.6787 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0103 | 0.0080 | 0.0103 | 0.0080 | 0.0513 | 0.0502 | 0.1335 | 0.1285 | 0.0637 | 0.0582 | 0.0842 | 0.0683 | 0.6448 | 0.6787 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0080 | 0.0080 | 0.0319 | 0.0956 | 0.1873 | 0.1594 | 0.1912 | 0.1753 | 0.1434 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 14 | 0.3292 | 0.40 | 0.993 | 0.6993 | 96.6 | 1114.47 | 13902.1 | 185508 | 0.4877 | 0.1649 | 0.0427 | 0.0010 | 0.1299 | 0.0068 | 0.2175 | 0.0218 | 0.2344 | 0.0618 | 0.1940 | 0.1341 | 0.1196 | 0.2265 | 0.0482 | 0.2611 | 0.0121 | 0.2035 | 0.0016 | 0.0835 | 0.0015 | 0.0001 | 0.0101 | 0.0006 | 0.0312 | 0.0040 | 0.0680 | 0.0142 | 0.1176 | 0.0364 | 0.1753 | 0.0828 | 0.2208 | 0.1592 | 0.2235 | 0.3027 | 0.1521 | 0.4001 | 0.0590 | 0.1703 | 0.1271 | 0.2470 | 0.1772 | 0.2322 | 0.1954 | 0.1620 | 0.1825 | 0.0961 | 0.1334 | 0.0570 | 0.0783 | 0.0237 | 0.0376 | 0.0074 | 0.0095 | 0.0043 | 0.0081 | 0.0349 | 0.0676 | 0.1210 | 0.1670 | 0.1995 | 0.1880 | 0.1467 | 0.0671 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 561 | 247 | 4445 | 15033 | 466.1 | 65.09 | 63.62 | 138.06 | 379 | 413 | 433 | 450 | 466 | 481 | 499 | 521 | 551 | 0.0559 | 840 | 1.186 | 46.40 | 17.49 | 1 | 0.0270 | 120 | 0.0015 | 34.76 | 6.820 | 0.2169 | 221513.0 | 107000000 | 52800000000 | 26400000000000 | 0.4116 | 0.2311 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0035 | 0.0002 | 0.0355 | 0.0137 | 0.0646 | 0.0248 | 0.0635 | 0.0142 | 0.0910 | 0.0205 | 0.7407 | 0.9266 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0221 | 0.0137 | 0.0368 | 0.0248 | 0.0314 | 0.0142 | 0.0456 | 0.0187 | 0.8620 | 0.9284 | 0.0110 | 1.0000 | 0.0192 | 0.0000 | 0.0219 | 0.0000 | 0.0959 | 0.0000 | 0.1479 | 0.0000 | 0.1726 | 0.0000 | 0.1397 | 0.0000 | 0.1288 | 0.0000 | 0.2630 | 0.0000 | 0.0004 | 0.0036 | 0.0085 | 0.0278 | 0.0732 | 0.0996 | 0.0961 | 0.1302 | 0.5606 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 57 | 200 | 0.2619 | 11.61 | 3.053 | 0.7574 | 23105.5 | 14100000 | 11000000000 | 10100000000000 | 0.4691 | 0.1844 | 0.0363 | 0.0081 | 0.0726 | 0.0208 | 0.0726 | 0.0728 | 0.1501 | 0.0786 | 0.1622 | 0.1110 | 0.1671 | 0.1260 | 0.1574 | 0.1191 | 0.1090 | 0.1445 | 0.0726 | 0.3191 | 0.0003 | 0.0012 | 0.0013 | 0.0030 | 0.0023 | 0.0044 | 0.0077 | 0.0094 | 0.0229 | 0.0195 | 0.0265 | 0.0301 | 0.0245 | 0.0248 | 0.0368 | 0.0387 | 0.8777 | 0.8689 | 0.0011 | 0.0000 | 0.0011 | 0.0004 | 0.0022 | 0.0024 | 0.0108 | 0.0091 | 0.0238 | 0.0234 | 0.0309 | 0.0313 | 0.0313 | 0.0317 | 0.0395 | 0.0527 | 0.8593 | 0.8490 | 0.0003 | 0.0007 | 0.0048 | 0.0104 | 0.0214 | 0.0308 | 0.0235 | 0.0443 | 0.8637 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1131 | 915 | 2089 | 9754 | 430.7 | 88.27 | 4.29 | 2.29 | 312 | 347 | 379 | 402 | 426 | 453 | 480 | 511 | 554 | 0.0779 | 760 | 1.256 | 68.26 | 30.41 | 1 | 0.0881 | 184 | 0.0020 | 13.39 | 6.433 | 0.2835 | 193252.0 | 90100000 | 43400000000 | 21600000000000 | 0.4117 | 0.2216 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0069 | 0.0010 | 0.0138 | 0.0020 | 0.0535 | 0.0221 | 0.0680 | 0.0432 | 0.0688 | 0.0285 | 0.1016 | 0.0569 | 0.6845 | 0.8464 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0053 | 0.0005 | 0.0065 | 0.0005 | 0.0213 | 0.0187 | 0.0296 | 0.0360 | 0.0260 | 0.0149 | 0.0391 | 0.0316 | 0.8704 | 0.8979 | 0.0000 | 0.0417 | 0.0026 | 0.1042 | 0.0236 | 0.1042 | 0.0289 | 0.1458 | 0.0735 | 0.2083 | 0.0997 | 0.0833 | 0.0919 | 0.1458 | 0.1102 | 0.1250 | 0.5696 | 0.0417 | 0.0020 | 0.0000 | 0.0059 | 0.0129 | 0.0287 | 0.0416 | 0.0505 | 0.0921 | 0.7663 | 2 | 2 | 3 | 3 | 4 | 5 | 5 | 6 | 7 | 0.1846 | 0.51 | 1.036 | 0.4874 | 23.6 | 149.049 | 1043.77 | 7945.36 | 0.5246 | 0.1474 | 0.1109 | 0.0066 | 0.1934 | 0.0403 | 0.2941 | 0.1203 | 0.2455 | 0.1990 | 0.0984 | 0.2637 | 0.0452 | 0.2180 | 0.0124 | 0.1183 | 0.0000 | 0.0305 | 0.0000 | 0.0032 | 0.0060 | 0.0000 | 0.0262 | 0.0025 | 0.0778 | 0.0134 | 0.1544 | 0.0375 | 0.2136 | 0.0942 | 0.2173 | 0.1639 | 0.1817 | 0.2530 | 0.0965 | 0.2739 | 0.0264 | 0.1617 | 0.0166 | 0.0996 | 0.0561 | 0.2292 | 0.1352 | 0.2826 | 0.2123 | 0.2167 | 0.2213 | 0.1091 | 0.1892 | 0.0477 | 0.1151 | 0.0125 | 0.0451 | 0.0027 | 0.0090 | 0.0000 | 0.0060 | 0.0262 | 0.0778 | 0.1544 | 0.2136 | 0.2173 | 0.1817 | 0.0965 | 0.0264 | |||
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 555 | 532 | 3465 | 14759 | 319.8 | 107.54 | 6.73 | 2.27 | 198 | 221 | 243 | 273 | 310 | 350 | 374 | 394 | 435 | 0.0700 | 1033 | 1.221 | 77.39 | 27.66 | 2 | 0.0543 | 188 | 0.0057 | 5.18 | 5.576 | 0.4523 | 113808.0 | 45100000 | 19800000000 | 9650000000000 | 0.4430 | 0.1901 | 0.0028 | 0.0000 | 0.0063 | 0.0000 | 0.0042 | 0.0017 | 0.0245 | 0.0068 | 0.0756 | 0.0345 | 0.1436 | 0.0519 | 0.1289 | 0.0420 | 0.1646 | 0.0615 | 0.4496 | 0.8016 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0004 | 0.0012 | 0.0105 | 0.0031 | 0.0285 | 0.0271 | 0.0558 | 0.0389 | 0.0378 | 0.0249 | 0.0470 | 0.0408 | 0.8187 | 0.8639 | 0.0106 | 0.0000 | 0.0153 | 0.0071 | 0.0188 | 0.0035 | 0.0259 | 0.0390 | 0.0506 | 0.0887 | 0.0576 | 0.0957 | 0.0682 | 0.0780 | 0.0988 | 0.0993 | 0.6541 | 0.5887 | 0.0000 | 0.0024 | 0.0018 | 0.0152 | 0.0328 | 0.0425 | 0.0334 | 0.0468 | 0.8251 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0844 | 0.35 | 0.898 | 0.3300 | 50.5 | 413.246 | 3661.4 | 35082.4 | 0.5392 | 0.1292 | 0.0068 | 0.0003 | 0.0451 | 0.0042 | 0.1067 | 0.0171 | 0.1894 | 0.0476 | 0.2341 | 0.0957 | 0.2205 | 0.1698 | 0.1356 | 0.2507 | 0.0525 | 0.2678 | 0.0093 | 0.1466 | 0.0014 | 0.0002 | 0.0128 | 0.0021 | 0.0344 | 0.0077 | 0.0739 | 0.0219 | 0.1043 | 0.0520 | 0.1474 | 0.0981 | 0.1623 | 0.1436 | 0.2138 | 0.2421 | 0.2497 | 0.4324 | 0.1133 | 0.1976 | 0.1372 | 0.2142 | 0.1664 | 0.1783 | 0.1654 | 0.1636 | 0.1518 | 0.1123 | 0.1186 | 0.0744 | 0.0801 | 0.0372 | 0.0458 | 0.0160 | 0.0213 | 0.0064 | 0.0167 | 0.0531 | 0.0922 | 0.1109 | 0.1310 | 0.1500 | 0.1506 | 0.1588 | 0.1366 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1087 | 911 | 930 | 11171 | 100.7 | 22.55 | 6.80 | 4.19 | 73 | 79 | 86 | 93 | 99 | 105 | 111 | 121 | 133 | 0.0929 | 1038 | 1.197 | 26.91 | 10.82 | 2 | 0.0774 | 72 | 0.0206 | 2.16 | 4.113 | 0.5375 | 10648.5 | 1180000 | 137000000 | 16400000000 | 0.4115 | 0.2236 | 0.0018 | 0.0000 | 0.0037 | 0.0000 | 0.0147 | 0.0000 | 0.0403 | 0.0124 | 0.1007 | 0.0305 | 0.1941 | 0.0837 | 0.1905 | 0.0679 | 0.1978 | 0.1007 | 0.2564 | 0.7048 | 0.0014 | 0.0000 | 0.0027 | 0.0000 | 0.0041 | 0.0000 | 0.0192 | 0.0076 | 0.0426 | 0.0259 | 0.0852 | 0.0615 | 0.0742 | 0.0356 | 0.0989 | 0.0604 | 0.6717 | 0.8091 | 0.0000 | 0.0000 | 0.0549 | 0.0930 | 0.0275 | 0.1860 | 0.0769 | 0.1395 | 0.1593 | 0.1860 | 0.1538 | 0.1395 | 0.1209 | 0.1163 | 0.1209 | 0.0930 | 0.2857 | 0.0465 | 0.0023 | 0.0090 | 0.0248 | 0.0451 | 0.0858 | 0.1038 | 0.1264 | 0.1400 | 0.4628 | 3 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0170 | 13.34 | 4.491 | 0.3256 | 63.8 | 1717.75 | 142090 | 15800000 | 0.5342 | 0.1420 | 0.0158 | 0.0014 | 0.0687 | 0.0050 | 0.1509 | 0.0230 | 0.2289 | 0.0598 | 0.2453 | 0.1230 | 0.1792 | 0.2071 | 0.0851 | 0.2655 | 0.0242 | 0.2267 | 0.0020 | 0.0886 | 0.0031 | 0.0005 | 0.0114 | 0.0019 | 0.0454 | 0.0090 | 0.1019 | 0.0309 | 0.1665 | 0.0623 | 0.2143 | 0.1166 | 0.2056 | 0.2038 | 0.1486 | 0.2942 | 0.1033 | 0.2809 | 0.1680 | 0.3284 | 0.2346 | 0.2618 | 0.2091 | 0.1411 | 0.1446 | 0.0713 | 0.0657 | 0.0392 | 0.0481 | 0.0415 | 0.0308 | 0.0337 | 0.0460 | 0.0329 | 0.0530 | 0.0502 | 0.0170 | 0.0545 | 0.1103 | 0.1645 | 0.1904 | 0.1942 | 0.1363 | 0.0771 | 0.0558 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1103 | 521 | 38572 | 41531 | 83.7 | 70.09 | 7.10 | 2.74 | 45 | 48 | 50 | 53 | 56 | 62 | 73 | 98 | 152 | 0.0457 | 1898 | 0.782 | 128.16 | 45.34 | 3 | 0.0101 | 390 | 0.0492 | 1.50 | 4.084 | 0.6882 | 11919.8 | 2870000 | 920000000 | 334000000000 | 0.4510 | 0.1895 | 0.0109 | 0.0089 | 0.0164 | 0.0172 | 0.0246 | 0.0246 | 0.0351 | 0.0389 | 0.0605 | 0.0504 | 0.0801 | 0.0590 | 0.0958 | 0.0673 | 0.1409 | 0.0885 | 0.5357 | 0.6452 | 0.0040 | 0.0067 | 0.0055 | 0.0130 | 0.0089 | 0.0188 | 0.0105 | 0.0286 | 0.0183 | 0.0354 | 0.0237 | 0.0412 | 0.0271 | 0.0468 | 0.0418 | 0.0594 | 0.8604 | 0.7500 | 0.0015 | 0.0009 | 0.0027 | 0.0019 | 0.0047 | 0.0041 | 0.0104 | 0.0090 | 0.0173 | 0.0159 | 0.0259 | 0.0282 | 0.0314 | 0.0309 | 0.0401 | 0.0398 | 0.8660 | 0.8695 | 0.0020 | 0.0024 | 0.0056 | 0.0088 | 0.0174 | 0.0214 | 0.0294 | 0.0366 | 0.8764 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 9 | 11 | 0.4747 | 0.33 | 1.180 | 0.8414 | 57.9 | 527.37 | 5295.83 | 58155.7 | 0.4995 | 0.1829 | 0.0184 | 0.0024 | 0.0723 | 0.0096 | 0.1551 | 0.0301 | 0.2242 | 0.0749 | 0.2394 | 0.1555 | 0.1742 | 0.2423 | 0.0889 | 0.2556 | 0.0251 | 0.1713 | 0.0024 | 0.0583 | 0.0022 | 0.0001 | 0.0106 | 0.0010 | 0.0291 | 0.0053 | 0.0623 | 0.0178 | 0.1060 | 0.0556 | 0.1606 | 0.1162 | 0.2066 | 0.1940 | 0.2316 | 0.2914 | 0.1910 | 0.3187 | 0.0905 | 0.1632 | 0.1612 | 0.2060 | 0.1796 | 0.1882 | 0.1754 | 0.1469 | 0.1412 | 0.1102 | 0.1007 | 0.0685 | 0.0624 | 0.0461 | 0.0489 | 0.0412 | 0.0401 | 0.0296 | 0.0110 | 0.0392 | 0.0830 | 0.1233 | 0.1517 | 0.1724 | 0.1677 | 0.1502 | 0.1015 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1235 | 928 | 3908 | 866 | 131.6 | 35.52 | 83.99 | 75.24 | 92 | 104 | 113 | 120 | 128 | 134 | 143 | 154 | 171 | 0.5855 | 507 | 1.261 | 98.62 | 31.32 | 1 | 0.0581 | 227 | 0.0023 | 24.71 | 6.369 | 0.2431 | 18576.3 | 2850000 | 480000000 | 90700000000 | 0.4962 | 0.1800 | 0.0025 | 0.0000 | 0.0025 | 0.0003 | 0.0091 | 0.0020 | 0.0313 | 0.0045 | 0.0844 | 0.0247 | 0.1671 | 0.0656 | 0.1560 | 0.0617 | 0.1844 | 0.1041 | 0.3627 | 0.7372 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0016 | 0.0107 | 0.0024 | 0.0488 | 0.0200 | 0.0837 | 0.0431 | 0.0755 | 0.0318 | 0.1153 | 0.0568 | 0.6620 | 0.8442 | 0.0109 | 0.0207 | 0.0125 | 0.0290 | 0.0498 | 0.0290 | 0.0888 | 0.1079 | 0.1495 | 0.1992 | 0.1947 | 0.1826 | 0.1137 | 0.0747 | 0.1340 | 0.1452 | 0.2461 | 0.2116 | 0.0012 | 0.0075 | 0.0184 | 0.0519 | 0.1308 | 0.1360 | 0.1314 | 0.1527 | 0.3700 | 16 | 24 | 36 | 50 | 62 | 79 | 105 | 130 | 176 | 0.0070 | 32.32 | 5.471 | 0.3545 | 12708.8 | 3020000 | 1050000000 | 473000000000 | 0.5943 | 0.0759 | 0.0880 | 0.0099 | 0.2240 | 0.0627 | 0.2160 | 0.0924 | 0.2480 | 0.1881 | 0.1600 | 0.2277 | 0.0560 | 0.2376 | 0.0080 | 0.0792 | 0.0000 | 0.0528 | 0.0000 | 0.0495 | 0.0150 | 0.0019 | 0.0200 | 0.0174 | 0.0324 | 0.0174 | 0.0549 | 0.0581 | 0.2893 | 0.2364 | 0.3566 | 0.3682 | 0.1322 | 0.1492 | 0.0574 | 0.0717 | 0.0424 | 0.0795 | 0.0072 | 0.0047 | 0.0217 | 0.0235 | 0.0580 | 0.0798 | 0.1051 | 0.1221 | 0.2754 | 0.2864 | 0.3370 | 0.3146 | 0.1123 | 0.0986 | 0.0507 | 0.0376 | 0.0326 | 0.0329 | 0.0151 | 0.0151 | 0.0272 | 0.1057 | 0.2779 | 0.3595 | 0.1178 | 0.0453 | 0.0363 | |||
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1217 | 492 | 4158 | 8748 | 478.3 | 77.87 | 112.81 | 236.09 | 376 | 414 | 441 | 464 | 483 | 499 | 516 | 535 | 574 | 0.0725 | 634 | 0.983 | 79.31 | 27.31 | 1 | 0.0536 | 223 | 0.0016 | 22.49 | 6.757 | 0.2408 | 234837.0 | 118000000 | 60800000000 | 31900000000000 | 0.3975 | 0.2479 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0070 | 0.0005 | 0.0263 | 0.0161 | 0.0444 | 0.0266 | 0.0456 | 0.0159 | 0.0702 | 0.0242 | 0.8058 | 0.9168 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0002 | 0.0174 | 0.0145 | 0.0277 | 0.0252 | 0.0261 | 0.0128 | 0.0397 | 0.0206 | 0.8859 | 0.9267 | 0.0048 | 0.0000 | 0.0048 | 0.0000 | 0.0096 | 0.0556 | 0.0264 | 0.0833 | 0.0769 | 0.1667 | 0.0817 | 0.1389 | 0.1082 | 0.1667 | 0.1034 | 0.1111 | 0.5841 | 0.2778 | 0.0014 | 0.0018 | 0.0063 | 0.0136 | 0.0407 | 0.0678 | 0.0691 | 0.0985 | 0.7010 | 5 | 7 | 8 | 9 | 10 | 12 | 22 | 146 | 413 | 0.1638 | 17.76 | 3.315 | 0.5824 | 68457.9 | 58700000 | 59900000000 | 68200000000000 | 0.3262 | 0.2943 | 0.0588 | 0.0025 | 0.2888 | 0.0296 | 0.2513 | 0.1605 | 0.1016 | 0.1951 | 0.1123 | 0.1975 | 0.0695 | 0.1383 | 0.1016 | 0.0864 | 0.0107 | 0.0963 | 0.0053 | 0.0938 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0005 | 0.0081 | 0.0076 | 0.0389 | 0.0360 | 0.0567 | 0.0536 | 0.0354 | 0.0337 | 0.0445 | 0.0469 | 0.8164 | 0.8208 | 0.0006 | 0.0006 | 0.0000 | 0.0012 | 0.0045 | 0.0041 | 0.0078 | 0.0088 | 0.0380 | 0.0364 | 0.0553 | 0.0634 | 0.0330 | 0.0346 | 0.0508 | 0.0511 | 0.8101 | 0.7999 | 0.0000 | 0.0000 | 0.0005 | 0.0123 | 0.0410 | 0.0511 | 0.0373 | 0.0453 | 0.8125 | |||
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1017 | 554 | 378 | 9755 | 70.8 | 9.18 | 6.27 | 2.35 | 58 | 62 | 65 | 69 | 72 | 74 | 76 | 79 | 82 | 0.0685 | 668 | 1.025 | 80.23 | 26.63 | 2 | 0.5556 | 210 | 0.0307 | 2.20 | 3.799 | 0.5317 | 5100.6 | 373029 | 27700000 | 2080000000 | 0.3766 | 0.2528 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0121 | 0.0053 | 0.0725 | 0.0556 | 0.0816 | 0.0635 | 0.0816 | 0.0503 | 0.1178 | 0.0688 | 0.6284 | 0.7566 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0116 | 0.0053 | 0.0607 | 0.0556 | 0.0665 | 0.0635 | 0.0520 | 0.0503 | 0.0838 | 0.0688 | 0.7197 | 0.7566 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.0000 | 0.0000 | 0.1333 | 0.0000 | 0.0000 | 0.0093 | 0.0139 | 0.0324 | 0.0694 | 0.0787 | 0.0972 | 0.1481 | 0.5509 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.2315 | 0.45 | 1.048 | 0.5873 | 44.8 | 356.698 | 3133.82 | 30121.9 | 0.5230 | 0.1563 | 0.0095 | 0.0016 | 0.0423 | 0.0054 | 0.1159 | 0.0156 | 0.1913 | 0.0399 | 0.2491 | 0.0756 | 0.2068 | 0.1496 | 0.1260 | 0.2580 | 0.0507 | 0.3008 | 0.0085 | 0.1535 | 0.0009 | 0.0000 | 0.0033 | 0.0003 | 0.0157 | 0.0022 | 0.0417 | 0.0102 | 0.0896 | 0.0267 | 0.1561 | 0.0434 | 0.2071 | 0.1072 | 0.2316 | 0.2692 | 0.2540 | 0.5409 | 0.0990 | 0.1881 | 0.1831 | 0.2085 | 0.1795 | 0.1599 | 0.1502 | 0.1178 | 0.1272 | 0.0944 | 0.0980 | 0.0655 | 0.0618 | 0.0505 | 0.0512 | 0.0589 | 0.0501 | 0.0565 | 0.0080 | 0.0313 | 0.0735 | 0.1349 | 0.1725 | 0.1695 | 0.1459 | 0.1396 | 0.1248 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 461 | 123 | 3257 | 6809 | 514.7 | 105.53 | 61.25 | 124.20 | 368 | 433 | 474 | 500 | 525 | 551 | 579 | 608 | 638 | 0.0824 | 561 | 0.766 | 87.00 | 16.03 | 3 | 0.0620 | 202 | 0.0010 | 52.75 | 7.148 | 0.1825 | 276060.0 | 153000000 | 86800000000 | 50400000000000 | 0.4286 | 0.2196 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0068 | 0.0000 | 0.0140 | 0.0013 | 0.0512 | 0.0198 | 0.0978 | 0.0406 | 0.0965 | 0.0227 | 0.1277 | 0.0373 | 0.6046 | 0.8782 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0029 | 0.0013 | 0.0220 | 0.0197 | 0.0447 | 0.0384 | 0.0293 | 0.0184 | 0.0411 | 0.0288 | 0.8596 | 0.8934 | 0.0077 | 0.1333 | 0.0173 | 0.1333 | 0.0288 | 0.0667 | 0.0865 | 0.1333 | 0.1404 | 0.2667 | 0.1442 | 0.1333 | 0.1231 | 0.0000 | 0.1654 | 0.1333 | 0.2865 | 0.0000 | 0.0011 | 0.0023 | 0.0079 | 0.0186 | 0.0514 | 0.0814 | 0.0729 | 0.1040 | 0.6605 | 7 | 9 | 11 | 12 | 14 | 19 | 31 | 56 | 175 | 0.1883 | 7.43 | 3.201 | 0.7374 | 19174.6 | 10600000 | 7360000000 | 5780000000000 | 0.4921 | 0.1647 | 0.0338 | 0.0142 | 0.0549 | 0.0252 | 0.0717 | 0.0377 | 0.0928 | 0.0660 | 0.1392 | 0.0849 | 0.1814 | 0.1289 | 0.2363 | 0.1321 | 0.1097 | 0.1525 | 0.0802 | 0.3585 | 0.0034 | 0.0045 | 0.0048 | 0.0078 | 0.0034 | 0.0111 | 0.0109 | 0.0167 | 0.0212 | 0.0279 | 0.0519 | 0.0507 | 0.0355 | 0.0423 | 0.0444 | 0.0591 | 0.8245 | 0.7799 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0073 | 0.0078 | 0.0334 | 0.0336 | 0.0465 | 0.0509 | 0.0302 | 0.0259 | 0.0522 | 0.0578 | 0.8280 | 0.8240 | 0.0008 | 0.0008 | 0.0046 | 0.0106 | 0.0236 | 0.0540 | 0.0274 | 0.0547 | 0.8237 | |
SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 841 | 100 | 7377 | 24941 | 386.3 | 96.75 | 88.88 | 190.82 | 262 | 298 | 330 | 360 | 385 | 408 | 433 | 466 | 515 | 0.0500 | 1246 | 0.563 | 94.76 | 26.17 | 2 | 0.0409 | 302 | 0.0008 | 47.55 | 7.415 | 0.1751 | 158588.0 | 68800000 | 31400000000 | 15000000000000 | 0.4311 | 0.2177 | 0.0002 | 0.0000 | 0.0031 | 0.0005 | 0.0070 | 0.0012 | 0.0283 | 0.0041 | 0.0813 | 0.0252 | 0.1505 | 0.0529 | 0.1401 | 0.0558 | 0.1607 | 0.0799 | 0.4286 | 0.7805 | 0.0000 | 0.0000 | 0.0011 | 0.0001 | 0.0023 | 0.0003 | 0.0099 | 0.0018 | 0.0340 | 0.0163 | 0.0593 | 0.0332 | 0.0508 | 0.0272 | 0.0661 | 0.0402 | 0.7764 | 0.8808 | 0.0040 | 0.0130 | 0.0066 | 0.0238 | 0.0139 | 0.0563 | 0.0615 | 0.0909 | 0.1315 | 0.1970 | 0.1606 | 0.1710 | 0.1269 | 0.1255 | 0.1401 | 0.1299 | 0.3549 | 0.1926 | 0.0005 | 0.0014 | 0.0043 | 0.0220 | 0.0674 | 0.1016 | 0.1003 | 0.1272 | 0.5753 | 4 | 5 | 7 | 8 | 10 | 12 | 18 | 103 | 322 | 0.1971 | 13.23 | 3.393 | 0.6457 | 44309.3 | 31100000 | 25500000000 | 23000000000000 | 0.4510 | 0.1554 | 0.0309 | 0.0028 | 0.1373 | 0.0130 | 0.2921 | 0.0763 | 0.2205 | 0.1516 | 0.1431 | 0.2140 | 0.0986 | 0.1898 | 0.0271 | 0.1395 | 0.0213 | 0.1116 | 0.0290 | 0.1014 | 0.0000 | 0.0003 | 0.0009 | 0.0005 | 0.0007 | 0.0016 | 0.0037 | 0.0063 | 0.0213 | 0.0191 | 0.0374 | 0.0318 | 0.0250 | 0.0278 | 0.0407 | 0.0377 | 0.8703 | 0.8748 | 0.0000 | 0.0002 | 0.0008 | 0.0004 | 0.0004 | 0.0019 | 0.0063 | 0.0064 | 0.0259 | 0.0282 | 0.0468 | 0.0526 | 0.0377 | 0.0404 | 0.0539 | 0.0614 | 0.8281 | 0.8084 | 0.0000 | 0.0004 | 0.0008 | 0.0042 | 0.0213 | 0.0423 | 0.0293 | 0.0477 | 0.8540 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 244 | 404 | 494 | 2485 | 92.6 | 12.71 | 8.21 | 2.59 | 77 | 82 | 85 | 87 | 91 | 94 | 99 | 105 | 111 | 0.1469 | 365 | 1.264 | 23.35 | 8.54 | 2 | 0.1215 | 60 | 0.0560 | 0.95 | 3.137 | 0.6794 | 8731.3 | 838707 | 82000000 | 8150000000 | 0.3994 | 0.2357 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0071 | 0.0000 | 0.0165 | 0.0020 | 0.0615 | 0.0405 | 0.1229 | 0.0749 | 0.0827 | 0.0283 | 0.1348 | 0.0445 | 0.5745 | 0.8097 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0020 | 0.0404 | 0.0405 | 0.0702 | 0.0749 | 0.0319 | 0.0283 | 0.0574 | 0.0445 | 0.7915 | 0.8097 | 0.0000 | 0.0000 | 0.0851 | 0.0000 | 0.1277 | 0.0000 | 0.1915 | 0.0000 | 0.2128 | 0.0000 | 0.1702 | 0.0000 | 0.1064 | 0.0000 | 0.1064 | 0.0000 | 0.0000 | 0.0000 | 0.0089 | 0.0133 | 0.0089 | 0.0356 | 0.0667 | 0.0889 | 0.0933 | 0.1200 | 0.5644 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0177 | 10.75 | 4.510 | 0.3406 | 74.1 | 727.275 | 7718.61 | 88127.3 | 0.5118 | 0.1497 | 0.0233 | 0.0000 | 0.0933 | 0.0043 | 0.1707 | 0.0071 | 0.2341 | 0.0331 | 0.2211 | 0.0576 | 0.1763 | 0.0997 | 0.0606 | 0.1790 | 0.0187 | 0.3226 | 0.0019 | 0.2966 | 0.0017 | 0.0000 | 0.0207 | 0.0013 | 0.0407 | 0.0030 | 0.0878 | 0.0127 | 0.1228 | 0.0348 | 0.1641 | 0.0556 | 0.1922 | 0.0824 | 0.1876 | 0.2238 | 0.1824 | 0.5864 | 0.1028 | 0.2563 | 0.1416 | 0.2059 | 0.1490 | 0.1681 | 0.1714 | 0.1261 | 0.1222 | 0.1176 | 0.1386 | 0.0588 | 0.1073 | 0.0504 | 0.0566 | 0.0168 | 0.0104 | 0.0000 | 0.0115 | 0.0413 | 0.0678 | 0.1287 | 0.1430 | 0.1714 | 0.1850 | 0.1558 | 0.0955 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 744 | 960 | 1387 | 3556 | 629.5 | 191.17 | 8.12 | 2.69 | 392 | 452 | 506 | 568 | 633 | 689 | 744 | 805 | 887 | 0.1018 | 362 | 0.912 | 64.03 | 21.95 | 1 | 0.1327 | 184 | 0.0012 | 48.33 | 6.819 | 0.1637 | 432781.0 | 318000000 | 246000000000 | 199000000000000 | 0.4120 | 0.2104 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0017 | 0.0009 | 0.0325 | 0.0035 | 0.0959 | 0.0451 | 0.1935 | 0.0911 | 0.1336 | 0.0539 | 0.1781 | 0.0955 | 0.3647 | 0.7091 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0008 | 0.0339 | 0.0265 | 0.0749 | 0.0671 | 0.0441 | 0.0265 | 0.0575 | 0.0491 | 0.7844 | 0.8300 | 0.0000 | 0.0000 | 0.0051 | 0.0066 | 0.0128 | 0.0331 | 0.0128 | 0.0795 | 0.0821 | 0.0464 | 0.1000 | 0.1192 | 0.0641 | 0.1457 | 0.1128 | 0.1523 | 0.6103 | 0.4172 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0542 | 0.0842 | 0.0585 | 0.0899 | 0.7076 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0154 | 10.10 | 4.587 | 0.3257 | 73.1 | 722.744 | 7786.33 | 91072.8 | 0.4504 | 0.1710 | 0.0187 | 0.0017 | 0.0727 | 0.0055 | 0.1602 | 0.0051 | 0.2600 | 0.0301 | 0.2471 | 0.0623 | 0.1641 | 0.1057 | 0.0650 | 0.1978 | 0.0116 | 0.3022 | 0.0006 | 0.2895 | 0.0032 | 0.0000 | 0.0165 | 0.0021 | 0.0277 | 0.0015 | 0.0820 | 0.0134 | 0.1331 | 0.0375 | 0.1781 | 0.0643 | 0.1830 | 0.0972 | 0.2067 | 0.2291 | 0.1697 | 0.5548 | 0.1158 | 0.2444 | 0.1608 | 0.1750 | 0.1533 | 0.1583 | 0.1501 | 0.0944 | 0.1158 | 0.0556 | 0.0975 | 0.0889 | 0.0836 | 0.0694 | 0.0568 | 0.0861 | 0.0665 | 0.0278 | 0.0129 | 0.0378 | 0.0695 | 0.1311 | 0.1684 | 0.1913 | 0.1669 | 0.1396 | 0.0825 |