High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1174 | 311 | | 4125 | 7344 | 106.9 | 25.00 | 95.02 | 65.57 | 79 | 86 | 92 | 98 | 103 | 109 | 116 | 125 | 138 | 0.1023 | 751 | 0.955 | 114.81 | 26.63 | 2 | 0.0635 | 262 | 0.0036 | 15.13 | 5.958 | 0.3042 | 12054.8 | 1440000 | 184000000 | 25200000000 | 0.4230 | 0.2295 | 0.0011 | 0.0000 | 0.0026 | 0.0000 | 0.0132 | 0.0000 | 0.0332 | 0.0023 | 0.0716 | 0.0184 | 0.1474 | 0.0522 | 0.1520 | 0.0434 | 0.1840 | 0.0814 | 0.3948 | 0.8023 | 0.0009 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0000 | 0.0104 | 0.0017 | 0.0361 | 0.0125 | 0.0742 | 0.0330 | 0.0721 | 0.0178 | 0.1028 | 0.0425 | 0.6984 | 0.8924 | 0.0114 | 0.0226 | 0.0142 | 0.0136 | 0.0299 | 0.0452 | 0.0882 | 0.1041 | 0.1437 | 0.2308 | 0.1650 | 0.1719 | 0.1294 | 0.0860 | 0.1479 | 0.1357 | 0.2703 | 0.1900 | 0.0022 | 0.0061 | 0.0116 | 0.0476 | 0.0946 | 0.1489 | 0.1162 | 0.1417 | 0.4311 | 33 | 44 | 55 | 64 | 75 | 90 | 109 | 136 | 188 | 0.0069 | 12.75 | 5.650 | 0.3987 | 13326.8 | 2540000 | 606000000 | 170000000000 | 0.5934 | 0.1414 | 0.0211 | 0.0026 | 0.0695 | 0.0090 | 0.1538 | 0.0214 | 0.1669 | 0.0503 | 0.2066 | 0.1290 | 0.1650 | 0.1834 | 0.1123 | 0.1498 | 0.0707 | 0.1727 | 0.0341 | 0.2817 | 0.0014 | 0.0016 | 0.0049 | 0.0026 | 0.0140 | 0.0038 | 0.0343 | 0.0158 | 0.0954 | 0.0660 | 0.1604 | 0.1257 | 0.1242 | 0.0971 | 0.1310 | 0.1405 | 0.4345 | 0.5469 | 0.0049 | 0.0052 | 0.0152 | 0.0143 | 0.0236 | 0.0448 | 0.0594 | 0.0656 | 0.1233 | 0.1195 | 0.1724 | 0.1961 | 0.1243 | 0.1188 | 0.1464 | 0.1338 | 0.3306 | 0.3019 | 0.0022 | 0.0084 | 0.0205 | 0.0513 | 0.1081 | 0.1729 | 0.1198 | 0.1414 | 0.3755 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1017 | 174 | | 1248 | 1851 | 214.5 | 155.04 | 45.32 | 44.12 | 105 | 122 | 135 | 145 | 159 | 175 | 196 | 246 | 453 | 0.2150 | 398 | 0.886 | 138.05 | 45.25 | 2 | 0.3045 | 380 | 0.0030 | 54.71 | 6.166 | 0.2695 | 70037.8 | 33300000 | 19600000000 | 12700000000000 | 0.3408 | 0.2642 | 0.0000 | 0.0014 | 0.0105 | 0.0000 | 0.0592 | 0.0027 | 0.0941 | 0.0095 | 0.2056 | 0.0846 | 0.1638 | 0.1419 | 0.0906 | 0.1132 | 0.1289 | 0.1050 | 0.2474 | 0.5416 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0076 | 0.0011 | 0.0191 | 0.0085 | 0.0841 | 0.0512 | 0.1071 | 0.0800 | 0.0650 | 0.0597 | 0.1071 | 0.0778 | 0.6099 | 0.7207 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0169 | 0.0098 | 0.0805 | 0.1073 | 0.1059 | 0.1024 | 0.0551 | 0.0488 | 0.0975 | 0.1024 | 0.6441 | 0.6293 | 0.0032 | 0.0097 | 0.0097 | 0.0130 | 0.0909 | 0.0942 | 0.0390 | 0.1039 | 0.6364 | 20 | 22 | 25 | 27 | 30 | 34 | 39 | 51 | 87 | 0.1634 | 0.96 | 2.528 | 0.7872 | 4000.0 | 623754 | 127000000 | 29000000000 | 0.5672 | 0.0956 | 0.0344 | 0.0145 | 0.0875 | 0.0190 | 0.1375 | 0.0335 | 0.1313 | 0.0760 | 0.1906 | 0.1229 | 0.2000 | 0.1508 | 0.1156 | 0.1620 | 0.0688 | 0.1721 | 0.0344 | 0.2492 | 0.0106 | 0.0111 | 0.0257 | 0.0146 | 0.0287 | 0.0231 | 0.0332 | 0.0446 | 0.0861 | 0.0788 | 0.1344 | 0.0925 | 0.1239 | 0.1071 | 0.1360 | 0.1500 | 0.4215 | 0.4781 | 0.0029 | 0.0037 | 0.0088 | 0.0368 | 0.0205 | 0.0404 | 0.0526 | 0.0772 | 0.1404 | 0.0919 | 0.1725 | 0.1287 | 0.1023 | 0.1213 | 0.1287 | 0.1103 | 0.3713 | 0.3897 | 0.0022 | 0.0155 | 0.0310 | 0.0376 | 0.1062 | 0.1372 | 0.1261 | 0.1482 | 0.3960 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 906 | 300 | | 4616 | 2545 | 127.3 | 33.98 | 169.06 | 144.46 | 93 | 100 | 108 | 114 | 121 | 129 | 137 | 149 | 170 | 0.2303 | 586 | 0.655 | 101.26 | 21.10 | 1 | 0.0570 | 263 | 0.0024 | 23.69 | 6.393 | 0.2429 | 17366.0 | 2560000 | 415000000 | 74600000000 | 0.4222 | 0.2295 | 0.0007 | 0.0000 | 0.0025 | 0.0000 | 0.0079 | 0.0000 | 0.0229 | 0.0026 | 0.0947 | 0.0259 | 0.1804 | 0.0581 | 0.1701 | 0.0504 | 0.1851 | 0.0910 | 0.3358 | 0.7719 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0030 | 0.0000 | 0.0099 | 0.0013 | 0.0432 | 0.0143 | 0.0842 | 0.0317 | 0.0803 | 0.0229 | 0.1119 | 0.0419 | 0.6656 | 0.8878 | 0.0036 | 0.0107 | 0.0024 | 0.0000 | 0.0358 | 0.0188 | 0.0896 | 0.0965 | 0.1290 | 0.1662 | 0.1673 | 0.2011 | 0.1159 | 0.1421 | 0.1398 | 0.1582 | 0.3166 | 0.2064 | 0.0041 | 0.0041 | 0.0086 | 0.0436 | 0.0933 | 0.1379 | 0.1206 | 0.1409 | 0.4470 | 36 | 55 | 71 | 93 | 121 | 154 | 206 | 274 | 374 | 0.0029 | 65.12 | 6.499 | 0.2709 | 49440.3 | 19800000 | 9460000000 | 5070000000000 | 0.5100 | 0.1410 | 0.0427 | 0.0025 | 0.1467 | 0.0272 | 0.3413 | 0.0938 | 0.1973 | 0.1284 | 0.1040 | 0.2062 | 0.0960 | 0.2185 | 0.0400 | 0.1173 | 0.0240 | 0.1099 | 0.0080 | 0.0963 | 0.0009 | 0.0000 | 0.0061 | 0.0027 | 0.0182 | 0.0089 | 0.0425 | 0.0336 | 0.0981 | 0.0960 | 0.1389 | 0.1289 | 0.1076 | 0.0981 | 0.1250 | 0.1310 | 0.4627 | 0.5007 | 0.0026 | 0.0031 | 0.0064 | 0.0062 | 0.0154 | 0.0278 | 0.0605 | 0.0571 | 0.1107 | 0.1142 | 0.1725 | 0.1821 | 0.1042 | 0.1049 | 0.1184 | 0.1219 | 0.4093 | 0.3827 | 0.0021 | 0.0086 | 0.0182 | 0.0376 | 0.1116 | 0.1642 | 0.0998 | 0.1202 | 0.4378 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 789 | 385 | | 5318 | 5252 | 117.1 | 28.29 | 183.50 | 149.81 | 88 | 95 | 101 | 106 | 111 | 118 | 126 | 135 | 153 | 0.1359 | 714 | 1.185 | 99.25 | 31.11 | 1 | 0.0440 | 234 | 0.0038 | 12.98 | 5.962 | 0.3134 | 14501.7 | 1920000 | 277000000 | 44100000000 | 0.4157 | 0.2302 | 0.0009 | 0.0000 | 0.0020 | 0.0000 | 0.0054 | 0.0000 | 0.0148 | 0.0014 | 0.0594 | 0.0200 | 0.1213 | 0.0451 | 0.1410 | 0.0401 | 0.1627 | 0.0615 | 0.4926 | 0.8319 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0000 | 0.0092 | 0.0002 | 0.0304 | 0.0127 | 0.0533 | 0.0251 | 0.0612 | 0.0134 | 0.0839 | 0.0215 | 0.7570 | 0.9271 | 0.0036 | 0.0085 | 0.0107 | 0.0142 | 0.0130 | 0.0342 | 0.0627 | 0.0883 | 0.1456 | 0.2023 | 0.1692 | 0.1766 | 0.0994 | 0.0855 | 0.1669 | 0.1595 | 0.3290 | 0.2308 | 0.0013 | 0.0072 | 0.0103 | 0.0354 | 0.0752 | 0.1150 | 0.1115 | 0.1352 | 0.5090 | 34 | 56 | 79 | 108 | 140 | 180 | 233 | 298 | 398 | 0.0028 | 51.84 | 6.696 | 0.3006 | 56111.0 | 22900000 | 11200000000 | 6260000000000 | 0.5751 | 0.1077 | 0.0275 | 0.0017 | 0.1066 | 0.0098 | 0.2575 | 0.0574 | 0.1760 | 0.1074 | 0.1701 | 0.1895 | 0.1401 | 0.1959 | 0.0671 | 0.1430 | 0.0299 | 0.1310 | 0.0251 | 0.1643 | 0.0008 | 0.0000 | 0.0024 | 0.0010 | 0.0052 | 0.0029 | 0.0226 | 0.0226 | 0.0755 | 0.0634 | 0.1156 | 0.0976 | 0.0898 | 0.0789 | 0.1017 | 0.0957 | 0.5866 | 0.6379 | 0.0012 | 0.0007 | 0.0024 | 0.0052 | 0.0125 | 0.0163 | 0.0458 | 0.0570 | 0.0903 | 0.1117 | 0.1729 | 0.1805 | 0.1028 | 0.1139 | 0.1147 | 0.1220 | 0.4575 | 0.3928 | 0.0005 | 0.0044 | 0.0068 | 0.0311 | 0.0856 | 0.1465 | 0.0934 | 0.1226 | 0.5090 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 706 | 476 | | 728 | 1022 | 96.1 | 32.97 | 217.29 | 252.33 | 64 | 70 | 76 | 81 | 87 | 93 | 104 | 119 | 143 | 0.2652 | 271 | 0.410 | 145.45 | 41.40 | 1 | 0.7843 | 571 | 0.0039 | 22.73 | 5.781 | 0.2516 | 10321.1 | 1250000 | 169000000 | 25300000000 | 0.4351 | 0.2119 | 0.0000 | 0.0000 | 0.0173 | 0.0066 | 0.0202 | 0.0099 | 0.0980 | 0.0066 | 0.2161 | 0.0724 | 0.2017 | 0.0938 | 0.2017 | 0.0674 | 0.1441 | 0.1628 | 0.1009 | 0.5806 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0296 | 0.0029 | 0.1006 | 0.0471 | 0.1381 | 0.0799 | 0.1282 | 0.0428 | 0.1440 | 0.1084 | 0.4576 | 0.7190 | 0.0000 | 0.0215 | 0.0000 | 0.0000 | 0.0375 | 0.0000 | 0.0625 | 0.0753 | 0.1438 | 0.1183 | 0.1563 | 0.1720 | 0.1063 | 0.2151 | 0.1438 | 0.1398 | 0.3500 | 0.2581 | 0.0037 | 0.0000 | 0.0112 | 0.0669 | 0.1227 | 0.1450 | 0.0558 | 0.1004 | 0.4944 | 18 | 22 | 28 | 45 | 88 | 168 | 297 | 431 | 602 | 0.0497 | 49.53 | 4.975 | 0.4355 | 110822.0 | 73200000 | 55400000000 | 45800000000000 | 0.5813 | 0.0827 | 0.1029 | 0.0000 | 0.2500 | 0.0581 | 0.3971 | 0.1806 | 0.1324 | 0.2581 | 0.0735 | 0.2387 | 0.0147 | 0.1355 | 0.0294 | 0.0774 | 0.0000 | 0.0387 | 0.0000 | 0.0129 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0074 | 0.0022 | 0.0074 | 0.0285 | 0.0695 | 0.0724 | 0.1390 | 0.1162 | 0.0893 | 0.0943 | 0.1216 | 0.1250 | 0.5608 | 0.5592 | 0.0000 | 0.0000 | 0.0000 | 0.0033 | 0.0090 | 0.0000 | 0.0090 | 0.0233 | 0.0746 | 0.0731 | 0.1731 | 0.1728 | 0.0836 | 0.1163 | 0.1313 | 0.1262 | 0.5194 | 0.4851 | 0.0000 | 0.0000 | 0.0028 | 0.0110 | 0.0579 | 0.1818 | 0.0661 | 0.1350 | 0.5455 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1022 | 692 | | 3454 | 3530 | 167.4 | 41.65 | 180.50 | 117.23 | 122 | 134 | 143 | 152 | 160 | 170 | 182 | 197 | 221 | 0.1552 | 548 | 0.994 | 92.70 | 30.02 | 1 | 0.0753 | 260 | 0.0018 | 25.32 | 6.610 | 0.2337 | 29750.6 | 5640000 | 1140000000 | 247000000000 | 0.4167 | 0.2267 | 0.0019 | 0.0000 | 0.0014 | 0.0000 | 0.0079 | 0.0019 | 0.0200 | 0.0045 | 0.0723 | 0.0243 | 0.1361 | 0.0530 | 0.1441 | 0.0501 | 0.1716 | 0.0728 | 0.4448 | 0.7935 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0033 | 0.0000 | 0.0094 | 0.0012 | 0.0333 | 0.0171 | 0.0716 | 0.0339 | 0.0651 | 0.0233 | 0.0763 | 0.0369 | 0.7401 | 0.8876 | 0.0048 | 0.0078 | 0.0032 | 0.0078 | 0.0193 | 0.0273 | 0.0612 | 0.0898 | 0.1433 | 0.1406 | 0.1578 | 0.2031 | 0.1111 | 0.0898 | 0.1481 | 0.1680 | 0.3510 | 0.2656 | 0.0027 | 0.0040 | 0.0121 | 0.0336 | 0.0666 | 0.1217 | 0.0941 | 0.1163 | 0.5488 | 51 | 75 | 99 | 126 | 155 | 189 | 229 | 282 | 342 | 0.0019 | 49.51 | 6.719 | 0.2474 | 46319.3 | 14800000 | 5500000000 | 2270000000000 | 0.4820 | 0.1669 | 0.0110 | 0.0014 | 0.0992 | 0.0081 | 0.1983 | 0.0359 | 0.1832 | 0.0670 | 0.1749 | 0.1475 | 0.1405 | 0.2023 | 0.0992 | 0.1387 | 0.0702 | 0.1732 | 0.0234 | 0.2260 | 0.0011 | 0.0004 | 0.0032 | 0.0013 | 0.0053 | 0.0038 | 0.0185 | 0.0162 | 0.0678 | 0.0489 | 0.1070 | 0.0919 | 0.0970 | 0.0655 | 0.1436 | 0.1123 | 0.5564 | 0.6597 | 0.0017 | 0.0000 | 0.0078 | 0.0103 | 0.0138 | 0.0126 | 0.0491 | 0.0515 | 0.0956 | 0.1214 | 0.1731 | 0.1901 | 0.1051 | 0.1420 | 0.1447 | 0.1741 | 0.4091 | 0.2978 | 0.0013 | 0.0040 | 0.0047 | 0.0330 | 0.0982 | 0.1365 | 0.1063 | 0.1466 | 0.4694 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 942 | 402 | | 3688 | 2332 | 151.8 | 43.28 | 180.50 | 133.21 | 108 | 117 | 125 | 132 | 140 | 151 | 164 | 182 | 212 | 0.2213 | 516 | 0.931 | 141.17 | 32.02 | 1 | 0.0876 | 323 | 0.0019 | 31.70 | 6.606 | 0.2258 | 24909.7 | 4450000 | 865000000 | 182000000000 | 0.4279 | 0.2128 | 0.0005 | 0.0000 | 0.0025 | 0.0003 | 0.0128 | 0.0000 | 0.0325 | 0.0040 | 0.1019 | 0.0306 | 0.1791 | 0.0553 | 0.1713 | 0.0550 | 0.1688 | 0.0767 | 0.3307 | 0.7782 | 0.0004 | 0.0000 | 0.0015 | 0.0003 | 0.0062 | 0.0000 | 0.0124 | 0.0017 | 0.0433 | 0.0179 | 0.0822 | 0.0261 | 0.0803 | 0.0228 | 0.1047 | 0.0391 | 0.6692 | 0.8922 | 0.0014 | 0.0000 | 0.0083 | 0.0028 | 0.0139 | 0.0165 | 0.0584 | 0.0771 | 0.1210 | 0.1460 | 0.1919 | 0.1983 | 0.1099 | 0.1102 | 0.1140 | 0.1295 | 0.3811 | 0.3196 | 0.0000 | 0.0041 | 0.0129 | 0.0272 | 0.0918 | 0.1162 | 0.0959 | 0.1312 | 0.5207 | 34 | 55 | 81 | 119 | 156 | 194 | 239 | 293 | 359 | 0.0027 | 61.54 | 6.549 | 0.2559 | 50319.2 | 17900000 | 7550000000 | 3670000000000 | 0.4809 | 0.1585 | 0.0235 | 0.0000 | 0.1362 | 0.0214 | 0.1643 | 0.0571 | 0.2136 | 0.1060 | 0.1573 | 0.1655 | 0.1221 | 0.2143 | 0.0798 | 0.1429 | 0.0540 | 0.1179 | 0.0493 | 0.1750 | 0.0000 | 0.0000 | 0.0048 | 0.0027 | 0.0137 | 0.0096 | 0.0299 | 0.0212 | 0.0792 | 0.0745 | 0.1317 | 0.1217 | 0.0800 | 0.0820 | 0.1309 | 0.1046 | 0.5299 | 0.5837 | 0.0037 | 0.0032 | 0.0111 | 0.0064 | 0.0172 | 0.0305 | 0.0382 | 0.0546 | 0.1207 | 0.1396 | 0.1736 | 0.1862 | 0.1219 | 0.1348 | 0.1515 | 0.1605 | 0.3621 | 0.2841 | 0.0020 | 0.0079 | 0.0188 | 0.0327 | 0.0962 | 0.1409 | 0.1111 | 0.1518 | 0.4385 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1275 | 136 | | 348 | 1761 | 24.9 | 4.56 | 12.04 | 4.73 | 19 | 21 | 22 | 24 | 25 | 26 | 27 | 29 | 31 | 0.1550 | 273 | 0.753 | 89.14 | 19.31 | 1 | 0.6466 | 225 | 0.0917 | 1.19 | 2.649 | 0.6279 | 641.9 | 17045.4 | 465908 | 13100000 | 0.3990 | 0.2249 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0283 | 0.0000 | 0.0850 | 0.0208 | 0.1377 | 0.0564 | 0.1903 | 0.0682 | 0.2510 | 0.0653 | 0.1984 | 0.1721 | 0.1053 | 0.6172 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0355 | 0.0145 | 0.0548 | 0.0609 | 0.0613 | 0.0522 | 0.0968 | 0.0551 | 0.2194 | 0.0725 | 0.5226 | 0.7449 | 0.0476 | 0.6250 | 0.1746 | 0.2500 | 0.1270 | 0.1250 | 0.2857 | 0.0000 | 0.1746 | 0.0000 | 0.1111 | 0.0000 | 0.0794 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0056 | 0.0278 | 0.0778 | 0.0889 | 0.1611 | 0.2111 | 0.2000 | 0.1722 | 0.0556 | 7 | 7 | 9 | 11 | 11 | 13 | 14 | 16 | 18 | 0.4459 | 0.26 | 0.850 | 0.7731 | 167.2 | 2583.98 | 43505.2 | 785905 | 0.4996 | 0.1549 | 0.0715 | 0.0083 | 0.1464 | 0.0379 | 0.2230 | 0.0592 | 0.2379 | 0.0981 | 0.1747 | 0.1637 | 0.0948 | 0.2202 | 0.0349 | 0.2239 | 0.0166 | 0.1508 | 0.0000 | 0.0379 | 0.0196 | 0.0065 | 0.0267 | 0.0196 | 0.0364 | 0.0224 | 0.0756 | 0.0427 | 0.0907 | 0.0782 | 0.1307 | 0.0941 | 0.1627 | 0.1260 | 0.1956 | 0.2288 | 0.2622 | 0.3816 | 0.0611 | 0.1433 | 0.0630 | 0.1533 | 0.1183 | 0.2067 | 0.1756 | 0.1600 | 0.1584 | 0.1267 | 0.1737 | 0.1000 | 0.1317 | 0.0667 | 0.0954 | 0.0333 | 0.0229 | 0.0100 | 0.0427 | 0.0380 | 0.0617 | 0.1032 | 0.1329 | 0.1696 | 0.1459 | 0.1969 | 0.1091 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 128 | | 4381 | 3891 | 142.2 | 45.53 | 116.54 | 68.03 | 93 | 105 | 115 | 124 | 134 | 144 | 156 | 174 | 206 | 0.1773 | 690 | 1.154 | 92.96 | 30.48 | 1 | 0.0539 | 236 | 0.0014 | 45.81 | 6.878 | 0.1869 | 22305.5 | 3870000 | 744000000 | 158000000000 | 0.4152 | 0.2335 | 0.0000 | 0.0000 | 0.0045 | 0.0003 | 0.0186 | 0.0022 | 0.0626 | 0.0091 | 0.1392 | 0.0365 | 0.1946 | 0.0890 | 0.1642 | 0.0862 | 0.1655 | 0.1307 | 0.2508 | 0.6460 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0038 | 0.0010 | 0.0190 | 0.0034 | 0.0514 | 0.0191 | 0.0936 | 0.0528 | 0.0787 | 0.0396 | 0.1148 | 0.0671 | 0.6372 | 0.8169 | 0.0021 | 0.0099 | 0.0063 | 0.0079 | 0.0264 | 0.0258 | 0.0738 | 0.0813 | 0.1276 | 0.1488 | 0.1762 | 0.1925 | 0.1171 | 0.1310 | 0.1403 | 0.1587 | 0.3302 | 0.2440 | 0.0016 | 0.0054 | 0.0136 | 0.0490 | 0.1017 | 0.1447 | 0.1181 | 0.1371 | 0.4287 | 38 | 55 | 71 | 88 | 106 | 126 | 145 | 172 | 209 | 0.0023 | 29.24 | 6.422 | 0.2512 | 18208.7 | 3510000 | 804000000 | 216000000000 | 0.4985 | 0.1471 | 0.0212 | 0.0005 | 0.0945 | 0.0070 | 0.1741 | 0.0289 | 0.1656 | 0.0690 | 0.1975 | 0.1573 | 0.1592 | 0.1669 | 0.0902 | 0.1493 | 0.0637 | 0.1728 | 0.0340 | 0.2483 | 0.0018 | 0.0000 | 0.0041 | 0.0011 | 0.0091 | 0.0040 | 0.0279 | 0.0190 | 0.0741 | 0.0623 | 0.1189 | 0.0845 | 0.1006 | 0.0758 | 0.1161 | 0.1217 | 0.5473 | 0.6316 | 0.0048 | 0.0023 | 0.0088 | 0.0137 | 0.0201 | 0.0286 | 0.0530 | 0.0766 | 0.1349 | 0.1646 | 0.1743 | 0.1737 | 0.1245 | 0.1234 | 0.1414 | 0.1349 | 0.3382 | 0.2823 | 0.0006 | 0.0069 | 0.0103 | 0.0322 | 0.0925 | 0.1516 | 0.1040 | 0.1338 | 0.4681 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1240 | 782 | | 5520 | 5479 | 133.2 | 23.75 | 110.66 | 100.88 | 104 | 113 | 119 | 126 | 132 | 138 | 144 | 152 | 163 | 0.1374 | 753 | 0.999 | 91.29 | 24.70 | 1 | 0.0397 | 219 | 0.0031 | 14.38 | 6.066 | 0.2851 | 18294.8 | 2590000 | 379000000 | 57200000000 | 0.4125 | 0.2388 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0002 | 0.0212 | 0.0007 | 0.0442 | 0.0156 | 0.0934 | 0.0282 | 0.1204 | 0.0252 | 0.1646 | 0.0404 | 0.5507 | 0.8897 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0083 | 0.0002 | 0.0228 | 0.0129 | 0.0452 | 0.0203 | 0.0504 | 0.0132 | 0.0765 | 0.0234 | 0.7949 | 0.9300 | 0.0226 | 0.0169 | 0.0155 | 0.0763 | 0.0523 | 0.1102 | 0.1088 | 0.1102 | 0.1638 | 0.1525 | 0.1723 | 0.2034 | 0.1201 | 0.1356 | 0.1554 | 0.0847 | 0.1893 | 0.1102 | 0.0033 | 0.0089 | 0.0118 | 0.0380 | 0.0687 | 0.1048 | 0.1063 | 0.1384 | 0.5197 | 27 | 36 | 47 | 60 | 75 | 95 | 123 | 168 | 249 | 0.0062 | 29.53 | 5.971 | 0.3642 | 22419.6 | 6640000 | 2430000000 | 1010000000000 | 0.6287 | 0.0903 | 0.0259 | 0.0043 | 0.1147 | 0.0103 | 0.2160 | 0.0511 | 0.1732 | 0.0983 | 0.1395 | 0.1836 | 0.1192 | 0.1825 | 0.0934 | 0.1477 | 0.0742 | 0.1266 | 0.0439 | 0.1955 | 0.0017 | 0.0020 | 0.0034 | 0.0039 | 0.0089 | 0.0098 | 0.0326 | 0.0219 | 0.0852 | 0.0732 | 0.1360 | 0.1023 | 0.1004 | 0.0859 | 0.1513 | 0.1366 | 0.4805 | 0.5644 | 0.0020 | 0.0025 | 0.0095 | 0.0033 | 0.0102 | 0.0172 | 0.0428 | 0.0582 | 0.1292 | 0.1534 | 0.1747 | 0.1838 | 0.1237 | 0.1017 | 0.1475 | 0.1403 | 0.3603 | 0.3396 | 0.0016 | 0.0064 | 0.0155 | 0.0321 | 0.1095 | 0.1474 | 0.1239 | 0.1394 | 0.4241 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1272 | 883 | | 1150 | 8995 | 239.8 | 65.75 | 123.62 | 67.46 | 158 | 173 | 191 | 209 | 232 | 258 | 286 | 306 | 330 | 0.0845 | 760 | 0.982 | 95.52 | 25.18 | 3 | 0.2000 | 230 | 0.0013 | 67.56 | 6.741 | 0.1434 | 61808.3 | 17000000 | 4910000000 | 1480000000000 | 0.4669 | 0.1629 | 0.0043 | 0.0010 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0469 | 0.0068 | 0.1919 | 0.0476 | 0.2751 | 0.1322 | 0.1663 | 0.0787 | 0.1215 | 0.1351 | 0.1919 | 0.5986 | 0.0013 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0150 | 0.0045 | 0.0614 | 0.0303 | 0.0852 | 0.1025 | 0.0576 | 0.0357 | 0.0827 | 0.0677 | 0.6967 | 0.7585 | 0.0000 | 0.0108 | 0.0000 | 0.0323 | 0.0000 | 0.0538 | 0.0274 | 0.1720 | 0.1337 | 0.1398 | 0.1125 | 0.1613 | 0.1155 | 0.1720 | 0.1763 | 0.1075 | 0.4347 | 0.1505 | 0.0000 | 0.0000 | 0.0019 | 0.0242 | 0.0576 | 0.1022 | 0.0762 | 0.0929 | 0.6450 | 49 | 64 | 78 | 92 | 110 | 130 | 153 | 178 | 216 | 0.0036 | 19.57 | 6.129 | 0.3167 | 19833.3 | 3880000 | 886000000 | 230000000000 | 0.5219 | 0.1301 | 0.0186 | 0.0026 | 0.0971 | 0.0077 | 0.1631 | 0.0208 | 0.1817 | 0.0612 | 0.1719 | 0.1229 | 0.1524 | 0.1718 | 0.1115 | 0.1593 | 0.0678 | 0.1860 | 0.0358 | 0.2677 | 0.0012 | 0.0012 | 0.0034 | 0.0023 | 0.0078 | 0.0055 | 0.0254 | 0.0158 | 0.0730 | 0.0453 | 0.1045 | 0.0772 | 0.1015 | 0.0721 | 0.1389 | 0.1101 | 0.5443 | 0.6705 | 0.0011 | 0.0082 | 0.0102 | 0.0169 | 0.0186 | 0.0416 | 0.0629 | 0.0914 | 0.1265 | 0.1422 | 0.1757 | 0.1792 | 0.1409 | 0.1555 | 0.1452 | 0.1247 | 0.3188 | 0.2402 | 0.0018 | 0.0043 | 0.0128 | 0.0337 | 0.0856 | 0.1573 | 0.1206 | 0.1418 | 0.4421 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 127 | 580 | | 4890 | 10021 | 167.2 | 45.62 | 128.15 | 116.75 | 114 | 127 | 138 | 149 | 161 | 173 | 187 | 205 | 230 | 0.0875 | 877 | 0.739 | 103.47 | 30.61 | 1 | 0.0599 | 293 | 0.0011 | 49.25 | 7.043 | 0.1864 | 30027.2 | 5780000 | 1190000000 | 261000000000 | 0.4177 | 0.2308 | 0.0016 | 0.0002 | 0.0054 | 0.0005 | 0.0140 | 0.0014 | 0.0490 | 0.0063 | 0.1319 | 0.0305 | 0.2074 | 0.0675 | 0.1903 | 0.0781 | 0.1763 | 0.1142 | 0.2241 | 0.7013 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0025 | 0.0004 | 0.0156 | 0.0008 | 0.0542 | 0.0191 | 0.0826 | 0.0342 | 0.0846 | 0.0354 | 0.1043 | 0.0562 | 0.6544 | 0.8538 | 0.0018 | 0.0045 | 0.0120 | 0.0112 | 0.0221 | 0.0604 | 0.0766 | 0.1029 | 0.1485 | 0.2215 | 0.1845 | 0.1879 | 0.1236 | 0.1342 | 0.1494 | 0.1409 | 0.2814 | 0.1365 | 0.0005 | 0.0023 | 0.0104 | 0.0379 | 0.0974 | 0.1312 | 0.1028 | 0.1398 | 0.4779 | 18 | 32 | 51 | 70 | 93 | 120 | 156 | 205 | 286 | 0.0036 | 60.89 | 6.753 | 0.2645 | 30050.3 | 9900000 | 4030000000 | 1890000000000 | 0.5421 | 0.1392 | 0.0340 | 0.0028 | 0.1454 | 0.0145 | 0.2293 | 0.0767 | 0.1787 | 0.1127 | 0.1537 | 0.1622 | 0.1192 | 0.1926 | 0.0769 | 0.1335 | 0.0429 | 0.1338 | 0.0199 | 0.1711 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0043 | 0.0030 | 0.0229 | 0.0167 | 0.0712 | 0.0549 | 0.1280 | 0.1023 | 0.1062 | 0.0776 | 0.1235 | 0.1156 | 0.5418 | 0.6267 | 0.0023 | 0.0008 | 0.0052 | 0.0076 | 0.0124 | 0.0139 | 0.0322 | 0.0458 | 0.0970 | 0.1178 | 0.1758 | 0.1715 | 0.1120 | 0.1126 | 0.1143 | 0.1182 | 0.4489 | 0.4119 | 0.0005 | 0.0034 | 0.0093 | 0.0276 | 0.0928 | 0.1477 | 0.1082 | 0.1318 | 0.4785 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 644 | 509 | | 752 | 2601 | 109.3 | 22.70 | 27.66 | 36.83 | 79 | 89 | 97 | 104 | 110 | 117 | 123 | 130 | 139 | 0.1303 | 339 | 0.980 | 171.76 | 54.15 | 1 | 0.6197 | 466 | 0.0023 | 47.96 | 6.181 | 0.1607 | 12466.6 | 1470000 | 179000000 | 22400000000 | 0.3827 | 0.2423 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0151 | 0.0000 | 0.0538 | 0.0042 | 0.1075 | 0.0379 | 0.1613 | 0.0618 | 0.1527 | 0.0520 | 0.2022 | 0.0758 | 0.3032 | 0.7683 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0114 | 0.0041 | 0.0507 | 0.0346 | 0.0654 | 0.0553 | 0.0670 | 0.0346 | 0.1029 | 0.0581 | 0.7010 | 0.8133 | 0.0204 | 0.0000 | 0.0272 | 0.0909 | 0.0612 | 0.3636 | 0.0952 | 0.2727 | 0.1837 | 0.0909 | 0.1361 | 0.1818 | 0.1633 | 0.0000 | 0.1769 | 0.0000 | 0.1361 | 0.0000 | 0.0000 | 0.0025 | 0.0101 | 0.0404 | 0.0783 | 0.1364 | 0.1364 | 0.1338 | 0.4621 | 13 | 14 | 15 | 16 | 17 | 18 | 21 | 29 | 50 | 0.5312 | 1.01 | 1.471 | 0.9002 | 2121.0 | 439440 | 138000000 | 49900000000 | 0.6286 | 0.0988 | 0.0545 | 0.0328 | 0.0955 | 0.0864 | 0.2136 | 0.1351 | 0.2136 | 0.1033 | 0.1727 | 0.1360 | 0.1091 | 0.1360 | 0.0909 | 0.1241 | 0.0364 | 0.1311 | 0.0136 | 0.1152 | 0.0104 | 0.0219 | 0.0104 | 0.0629 | 0.0207 | 0.0950 | 0.0370 | 0.0673 | 0.1111 | 0.0994 | 0.1156 | 0.0892 | 0.1319 | 0.1001 | 0.1452 | 0.1235 | 0.4178 | 0.3406 | 0.0000 | 0.0000 | 0.0022 | 0.0249 | 0.0198 | 0.0305 | 0.0440 | 0.0693 | 0.1604 | 0.1662 | 0.1758 | 0.1801 | 0.1297 | 0.1468 | 0.1714 | 0.1634 | 0.2967 | 0.2188 | 0.0036 | 0.0073 | 0.0146 | 0.0419 | 0.1421 | 0.1512 | 0.1275 | 0.1658 | 0.3461 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 870 | 152 | | 2506 | 5703 | 72.8 | 23.73 | 226.65 | 206.12 | 44 | 52 | 59 | 65 | 71 | 77 | 83 | 92 | 106 | 0.1012 | 577 | 0.226 | 301.04 | 33.94 | 3 | 0.4254 | 1066 | 0.0017 | 34.53 | 6.624 | 0.1875 | 5856.8 | 514772 | 48800000 | 4950000000 | 0.4100 | 0.2367 | 0.0000 | 0.0000 | 0.0094 | 0.0000 | 0.0309 | 0.0015 | 0.0738 | 0.0082 | 0.1639 | 0.0494 | 0.1966 | 0.0937 | 0.1949 | 0.1105 | 0.1768 | 0.1549 | 0.1536 | 0.5818 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0009 | 0.0147 | 0.0035 | 0.0548 | 0.0288 | 0.0892 | 0.0399 | 0.0926 | 0.0465 | 0.1242 | 0.0798 | 0.6222 | 0.8005 | 0.0050 | 0.0068 | 0.0149 | 0.0068 | 0.0215 | 0.0375 | 0.0809 | 0.1024 | 0.1601 | 0.2321 | 0.1700 | 0.1945 | 0.1221 | 0.1229 | 0.1535 | 0.1468 | 0.2723 | 0.1502 | 0.0017 | 0.0025 | 0.0142 | 0.0418 | 0.0879 | 0.1431 | 0.1305 | 0.1423 | 0.4360 | 33 | 48 | 74 | 110 | 160 | 220 | 294 | 390 | 525 | 0.0110 | 30.01 | 5.917 | 0.3620 | 93846.7 | 52100000 | 34500000000 | 25800000000000 | 0.5031 | 0.1657 | 0.0592 | 0.0019 | 0.2513 | 0.0205 | 0.2592 | 0.1189 | 0.1526 | 0.1841 | 0.1079 | 0.1937 | 0.0921 | 0.1688 | 0.0434 | 0.1119 | 0.0224 | 0.0985 | 0.0118 | 0.1017 | 0.0000 | 0.0000 | 0.0023 | 0.0013 | 0.0080 | 0.0035 | 0.0221 | 0.0190 | 0.0865 | 0.0723 | 0.1319 | 0.1138 | 0.1021 | 0.0826 | 0.1444 | 0.1157 | 0.5027 | 0.5919 | 0.0011 | 0.0026 | 0.0038 | 0.0026 | 0.0145 | 0.0168 | 0.0376 | 0.0510 | 0.1175 | 0.1395 | 0.1760 | 0.1802 | 0.1180 | 0.1298 | 0.1352 | 0.1486 | 0.3965 | 0.3288 | 0.0009 | 0.0018 | 0.0086 | 0.0378 | 0.0991 | 0.1535 | 0.1153 | 0.1346 | 0.4484 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 95 | 131 | | 989 | 1640 | 89.4 | 13.84 | 29.47 | 62.84 | 71 | 77 | 82 | 85 | 89 | 93 | 96 | 101 | 107 | 0.2116 | 347 | 0.177 | 169.76 | 32.53 | 2 | 0.8817 | 872 | 0.0651 | 1.08 | 3.063 | 0.6829 | 8181.5 | 766522 | 73500000 | 7210000000 | 0.3997 | 0.2450 | 0.0013 | 0.0000 | 0.0025 | 0.0000 | 0.0063 | 0.0000 | 0.0304 | 0.0061 | 0.0608 | 0.0348 | 0.0989 | 0.0583 | 0.1343 | 0.0409 | 0.1926 | 0.0502 | 0.4728 | 0.8096 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0022 | 0.0000 | 0.0169 | 0.0051 | 0.0371 | 0.0293 | 0.0573 | 0.0526 | 0.0629 | 0.0303 | 0.0843 | 0.0415 | 0.7371 | 0.8413 | 0.0594 | 0.0000 | 0.1089 | 0.3333 | 0.1188 | 0.2500 | 0.1485 | 0.2500 | 0.1485 | 0.0833 | 0.1782 | 0.0833 | 0.0594 | 0.0000 | 0.0792 | 0.0000 | 0.0990 | 0.0000 | 0.0019 | 0.0077 | 0.0232 | 0.0522 | 0.0754 | 0.1006 | 0.1528 | 0.2147 | 0.3714 | 8 | 10 | 12 | 13 | 15 | 17 | 20 | 26 | 43 | 0.3370 | 1.57 | 1.900 | 0.7940 | 4815.1 | 2160000 | 1340000000 | 961000000000 | 0.6590 | 0.0663 | 0.0476 | 0.0571 | 0.1429 | 0.0571 | 0.1905 | 0.0813 | 0.2434 | 0.1099 | 0.2487 | 0.1429 | 0.0794 | 0.1868 | 0.0476 | 0.1890 | 0.0000 | 0.1341 | 0.0000 | 0.0418 | 0.0128 | 0.0413 | 0.0434 | 0.0366 | 0.0561 | 0.0461 | 0.0918 | 0.0636 | 0.1429 | 0.0986 | 0.1709 | 0.1574 | 0.1301 | 0.1558 | 0.1071 | 0.1558 | 0.2449 | 0.2448 | 0.0246 | 0.0057 | 0.0148 | 0.0230 | 0.0296 | 0.0345 | 0.0788 | 0.0575 | 0.1478 | 0.1609 | 0.1773 | 0.2126 | 0.1281 | 0.1149 | 0.1232 | 0.1437 | 0.2759 | 0.2471 | 0.0223 | 0.0335 | 0.0520 | 0.0632 | 0.1561 | 0.1710 | 0.1227 | 0.1190 | 0.2602 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 816 | 393 | | 5950 | 11342 | 117.6 | 33.32 | 249.29 | 173.91 | 81 | 90 | 98 | 105 | 112 | 120 | 129 | 141 | 162 | 0.0886 | 1005 | 0.628 | 179.79 | 48.30 | 1 | 0.0987 | 587 | 0.0027 | 14.82 | 6.257 | 0.2986 | 14935.3 | 2060000 | 307000000 | 49700000000 | 0.4437 | 0.2043 | 0.0009 | 0.0002 | 0.0033 | 0.0000 | 0.0082 | 0.0002 | 0.0331 | 0.0046 | 0.0759 | 0.0228 | 0.1588 | 0.0532 | 0.1527 | 0.0566 | 0.1907 | 0.0777 | 0.3764 | 0.7848 | 0.0005 | 0.0002 | 0.0014 | 0.0000 | 0.0036 | 0.0002 | 0.0167 | 0.0016 | 0.0351 | 0.0130 | 0.0689 | 0.0288 | 0.0680 | 0.0227 | 0.0975 | 0.0363 | 0.7084 | 0.8972 | 0.0052 | 0.0056 | 0.0070 | 0.0056 | 0.0235 | 0.0206 | 0.0506 | 0.0882 | 0.0950 | 0.1689 | 0.1578 | 0.1388 | 0.1046 | 0.1107 | 0.1290 | 0.1370 | 0.4272 | 0.3246 | 0.0020 | 0.0051 | 0.0094 | 0.0279 | 0.0822 | 0.1188 | 0.0917 | 0.1200 | 0.5429 | 40 | 81 | 128 | 176 | 225 | 279 | 333 | 394 | 483 | 0.0016 | 78.48 | 7.365 | 0.2033 | 92387.6 | 42200000 | 22200000000 | 13200000000000 | 0.4848 | 0.1839 | 0.0286 | 0.0012 | 0.1297 | 0.0127 | 0.2654 | 0.0476 | 0.1826 | 0.1174 | 0.1568 | 0.1874 | 0.1170 | 0.2093 | 0.0749 | 0.1488 | 0.0314 | 0.1305 | 0.0136 | 0.1451 | 0.0005 | 0.0000 | 0.0003 | 0.0013 | 0.0040 | 0.0026 | 0.0198 | 0.0140 | 0.0727 | 0.0554 | 0.1270 | 0.1033 | 0.1058 | 0.0836 | 0.1312 | 0.1196 | 0.5388 | 0.6202 | 0.0012 | 0.0026 | 0.0065 | 0.0077 | 0.0102 | 0.0148 | 0.0349 | 0.0586 | 0.1118 | 0.1501 | 0.1780 | 0.1978 | 0.1268 | 0.1369 | 0.1581 | 0.1553 | 0.3725 | 0.2761 | 0.0002 | 0.0031 | 0.0062 | 0.0306 | 0.0849 | 0.1491 | 0.1161 | 0.1500 | 0.4598 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 968 | 97 | | 4897 | 1372 | 105.7 | 28.33 | 79.73 | 69.69 | 76 | 82 | 88 | 94 | 100 | 107 | 114 | 125 | 145 | 0.3797 | 521 | 0.626 | 127.78 | 26.91 | 1 | 0.0764 | 374 | 0.0037 | 15.12 | 6.016 | 0.3192 | 11982.1 | 1460000 | 194000000 | 27700000000 | 0.4561 | 0.1953 | 0.0004 | 0.0000 | 0.0056 | 0.0005 | 0.0215 | 0.0032 | 0.0318 | 0.0068 | 0.0787 | 0.0290 | 0.1126 | 0.0432 | 0.1242 | 0.0375 | 0.1958 | 0.0681 | 0.4294 | 0.8118 | 0.0000 | 0.0000 | 0.0016 | 0.0004 | 0.0081 | 0.0004 | 0.0118 | 0.0016 | 0.0430 | 0.0150 | 0.0568 | 0.0214 | 0.0627 | 0.0183 | 0.1052 | 0.0342 | 0.7108 | 0.9086 | 0.0068 | 0.0046 | 0.0136 | 0.0068 | 0.0340 | 0.0114 | 0.0498 | 0.0683 | 0.1053 | 0.1663 | 0.1268 | 0.2005 | 0.1031 | 0.1435 | 0.1291 | 0.1344 | 0.4315 | 0.2642 | 0.0049 | 0.0049 | 0.0147 | 0.0339 | 0.0776 | 0.1036 | 0.1046 | 0.1297 | 0.5260 | 14 | 20 | 34 | 45 | 59 | 78 | 97 | 125 | 177 | 0.0145 | 15.01 | 5.234 | 0.4127 | 11210.5 | 2240000 | 575000000 | 180000000000 | 0.5721 | 0.0938 | 0.0633 | 0.0085 | 0.1629 | 0.0277 | 0.2081 | 0.1043 | 0.1448 | 0.1447 | 0.1357 | 0.1936 | 0.1222 | 0.1723 | 0.0950 | 0.1191 | 0.0317 | 0.1064 | 0.0362 | 0.1234 | 0.0061 | 0.0013 | 0.0076 | 0.0088 | 0.0244 | 0.0175 | 0.0809 | 0.0489 | 0.1481 | 0.1529 | 0.1664 | 0.1867 | 0.1405 | 0.1291 | 0.1145 | 0.1291 | 0.3115 | 0.3258 | 0.0069 | 0.0061 | 0.0253 | 0.0457 | 0.0346 | 0.0640 | 0.1152 | 0.0854 | 0.1843 | 0.1829 | 0.1797 | 0.1707 | 0.1267 | 0.1646 | 0.1221 | 0.1311 | 0.2051 | 0.1494 | 0.0019 | 0.0168 | 0.0243 | 0.0935 | 0.1832 | 0.1664 | 0.1383 | 0.1421 | 0.2336 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1062 | 176 | | 3821 | 1099 | 127.1 | 35.77 | 120.37 | 118.21 | 89 | 99 | 106 | 112 | 119 | 128 | 138 | 153 | 177 | 0.4277 | 470 | 0.928 | 118.11 | 36.14 | 1 | 0.0806 | 308 | 0.0024 | 20.54 | 6.389 | 0.2635 | 17441.2 | 2590000 | 418000000 | 72900000000 | 0.3965 | 0.2480 | 0.0023 | 0.0000 | 0.0014 | 0.0003 | 0.0093 | 0.0021 | 0.0332 | 0.0054 | 0.1037 | 0.0279 | 0.1780 | 0.0722 | 0.1575 | 0.0617 | 0.2164 | 0.0886 | 0.2981 | 0.7418 | 0.0007 | 0.0000 | 0.0003 | 0.0003 | 0.0031 | 0.0008 | 0.0131 | 0.0022 | 0.0475 | 0.0159 | 0.0825 | 0.0401 | 0.0829 | 0.0250 | 0.1186 | 0.0415 | 0.6513 | 0.8743 | 0.0078 | 0.0000 | 0.0065 | 0.0080 | 0.0169 | 0.0239 | 0.0482 | 0.0824 | 0.1172 | 0.1729 | 0.1602 | 0.2154 | 0.1107 | 0.0851 | 0.1549 | 0.1516 | 0.3776 | 0.2606 | 0.0025 | 0.0063 | 0.0163 | 0.0375 | 0.0864 | 0.1183 | 0.0970 | 0.1333 | 0.5025 | 16 | 29 | 41 | 59 | 80 | 108 | 145 | 193 | 282 | 0.0084 | 28.52 | 5.623 | 0.3574 | 28448.3 | 9780000 | 4200000000 | 2070000000000 | 0.4986 | 0.1225 | 0.0743 | 0.0125 | 0.1959 | 0.0498 | 0.2095 | 0.1059 | 0.2162 | 0.1558 | 0.1486 | 0.2118 | 0.0676 | 0.1589 | 0.0811 | 0.0997 | 0.0068 | 0.0903 | 0.0000 | 0.1153 | 0.0041 | 0.0034 | 0.0062 | 0.0102 | 0.0330 | 0.0170 | 0.0433 | 0.0408 | 0.1608 | 0.1548 | 0.1773 | 0.1939 | 0.1361 | 0.1207 | 0.1773 | 0.1531 | 0.2619 | 0.3061 | 0.0089 | 0.0075 | 0.0000 | 0.0037 | 0.0326 | 0.0225 | 0.0742 | 0.1049 | 0.1929 | 0.2060 | 0.1810 | 0.1685 | 0.1721 | 0.1461 | 0.1602 | 0.1648 | 0.1780 | 0.1760 | 0.0025 | 0.0099 | 0.0099 | 0.0591 | 0.1724 | 0.1847 | 0.1576 | 0.1749 | 0.2291 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 541 | 522 | | 7538 | 10729 | 182.1 | 53.16 | 151.55 | 105.15 | 123 | 138 | 150 | 162 | 173 | 185 | 200 | 220 | 253 | 0.0842 | 903 | 1.033 | 124.56 | 28.32 | 1 | 0.0358 | 270 | 0.0011 | 47.33 | 7.166 | 0.1859 | 35971.8 | 7740000 | 1820000000 | 464000000000 | 0.4607 | 0.1986 | 0.0008 | 0.0002 | 0.0033 | 0.0003 | 0.0110 | 0.0014 | 0.0358 | 0.0038 | 0.1099 | 0.0259 | 0.1983 | 0.0649 | 0.1693 | 0.0640 | 0.1888 | 0.0978 | 0.2827 | 0.7419 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0075 | 0.0010 | 0.0464 | 0.0143 | 0.0907 | 0.0329 | 0.0762 | 0.0285 | 0.1180 | 0.0474 | 0.6588 | 0.8759 | 0.0038 | 0.0055 | 0.0070 | 0.0083 | 0.0203 | 0.0290 | 0.0725 | 0.0981 | 0.1462 | 0.1630 | 0.1697 | 0.2003 | 0.1132 | 0.1077 | 0.1373 | 0.1436 | 0.3299 | 0.2445 | 0.0003 | 0.0050 | 0.0050 | 0.0400 | 0.1026 | 0.1488 | 0.1079 | 0.1417 | 0.4487 | 38 | 59 | 80 | 102 | 128 | 157 | 190 | 236 | 297 | 0.0020 | 46.88 | 6.872 | 0.2760 | 34024.8 | 9800000 | 3360000000 | 1320000000000 | 0.5574 | 0.1310 | 0.0165 | 0.0000 | 0.1056 | 0.0050 | 0.2130 | 0.0382 | 0.1703 | 0.0893 | 0.1387 | 0.1551 | 0.1488 | 0.2086 | 0.0826 | 0.1535 | 0.0716 | 0.1259 | 0.0528 | 0.2244 | 0.0005 | 0.0000 | 0.0002 | 0.0006 | 0.0020 | 0.0016 | 0.0138 | 0.0112 | 0.0620 | 0.0424 | 0.1227 | 0.0865 | 0.0888 | 0.0730 | 0.1299 | 0.1037 | 0.5802 | 0.6811 | 0.0006 | 0.0004 | 0.0029 | 0.0049 | 0.0119 | 0.0162 | 0.0365 | 0.0503 | 0.1192 | 0.1521 | 0.1812 | 0.1923 | 0.1190 | 0.1367 | 0.1520 | 0.1559 | 0.3768 | 0.2911 | 0.0002 | 0.0009 | 0.0049 | 0.0238 | 0.0980 | 0.1462 | 0.1128 | 0.1557 | 0.4576 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 820 | 689 | | 340 | 1923 | 397.1 | 79.43 | 199.34 | 201.26 | 294 | 333 | 352 | 372 | 390 | 408 | 435 | 465 | 504 | 0.1394 | 268 | 1.182 | 145.07 | 47.10 | 3 | 1.0029 | 341 | 0.0036 | 115.51 | 5.687 | 0.1125 | 163958.0 | 70300000 | 31200000000 | 14300000000000 | 0.3965 | 0.2306 | 0.0000 | 0.0000 | 0.0174 | 0.0000 | 0.0217 | 0.0000 | 0.0957 | 0.0245 | 0.1478 | 0.0890 | 0.1913 | 0.1196 | 0.1783 | 0.0706 | 0.1043 | 0.1135 | 0.2435 | 0.5828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0241 | 0.0118 | 0.1069 | 0.0737 | 0.1621 | 0.1121 | 0.1241 | 0.0619 | 0.1241 | 0.1003 | 0.4517 | 0.6401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0500 | 0.2308 | 0.1333 | 0.0000 | 0.2000 | 0.3077 | 0.2167 | 0.1538 | 0.0833 | 0.1538 | 0.1500 | 0.1538 | 0.1667 | 0.0000 | 0.0000 | 0.0000 | 0.0189 | 0.0818 | 0.1635 | 0.2075 | 0.1258 | 0.1635 | 0.2390 | 20 | 36 | 64 | 93 | 120 | 173 | 254 | 366 | 476 | 0.0098 | 59.99 | 5.843 | 0.3632 | 80219.5 | 45700000 | 32800000000 | 28000000000000 | 0.5269 | 0.1237 | 0.0813 | 0.0000 | 0.2536 | 0.0321 | 0.3971 | 0.1514 | 0.1579 | 0.2041 | 0.0478 | 0.2110 | 0.0287 | 0.2064 | 0.0144 | 0.0940 | 0.0191 | 0.0550 | 0.0000 | 0.0459 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0012 | 0.0042 | 0.0135 | 0.0156 | 0.0800 | 0.0582 | 0.1441 | 0.1163 | 0.0985 | 0.0789 | 0.1195 | 0.1184 | 0.5431 | 0.6075 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0057 | 0.0332 | 0.0361 | 0.1144 | 0.1347 | 0.1841 | 0.1822 | 0.1061 | 0.1101 | 0.1426 | 0.1480 | 0.4179 | 0.3833 | 0.0000 | 0.0000 | 0.0000 | 0.0142 | 0.1095 | 0.1551 | 0.1053 | 0.1351 | 0.4808 |