High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 318 | 624 | | 6835 | 14487 | 545.4 | 80.10 | 171.75 | 314.77 | 430 | 485 | 516 | 537 | 554 | 568 | 585 | 605 | 635 | 0.0583 | 845 | 0.559 | 146.51 | 30.07 | 3 | 0.0660 | 451 | 0.0011 | 31.34 | 7.160 | 0.2167 | 303826.0 | 173000000 | 99800000000 | 58700000000000 | 0.4423 | 0.2040 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0007 | 0.0219 | 0.0105 | 0.0376 | 0.0227 | 0.0393 | 0.0121 | 0.0589 | 0.0224 | 0.8363 | 0.9315 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0006 | 0.0138 | 0.0100 | 0.0230 | 0.0208 | 0.0226 | 0.0098 | 0.0272 | 0.0183 | 0.9111 | 0.9405 | 0.0093 | 0.0000 | 0.0163 | 0.0000 | 0.0280 | 0.0000 | 0.0676 | 0.0000 | 0.1189 | 0.0000 | 0.1352 | 0.0000 | 0.1119 | 0.0000 | 0.1119 | 0.0000 | 0.4009 | 0.0000 | 0.0008 | 0.0005 | 0.0050 | 0.0188 | 0.0379 | 0.0636 | 0.0767 | 0.0981 | 0.6986 | 11 | 13 | 15 | 19 | 25 | 47 | 102 | 252 | 575 | 0.1437 | 10.43 | 3.781 | 0.6289 | 128574.0 | 142000000 | 187000000000 | 273000000000000 | 0.3937 | 0.2546 | 0.0244 | 0.0022 | 0.0822 | 0.0126 | 0.1735 | 0.0445 | 0.1903 | 0.0867 | 0.2116 | 0.1890 | 0.1248 | 0.1883 | 0.0868 | 0.1401 | 0.0715 | 0.1371 | 0.0350 | 0.1994 | 0.0000 | 0.0005 | 0.0010 | 0.0007 | 0.0036 | 0.0030 | 0.0067 | 0.0079 | 0.0359 | 0.0345 | 0.0508 | 0.0483 | 0.0398 | 0.0391 | 0.0646 | 0.0606 | 0.7976 | 0.8055 | 0.0009 | 0.0007 | 0.0009 | 0.0010 | 0.0028 | 0.0020 | 0.0080 | 0.0081 | 0.0423 | 0.0430 | 0.0537 | 0.0696 | 0.0515 | 0.0545 | 0.0771 | 0.0794 | 0.7628 | 0.7418 | 0.0006 | 0.0014 | 0.0023 | 0.0093 | 0.0369 | 0.0544 | 0.0417 | 0.0668 | 0.7866 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1140 | 501 | | 2795 | 5688 | 534.4 | 104.94 | 43.08 | 68.58 | 388 | 442 | 474 | 506 | 538 | 572 | 599 | 634 | 676 | 0.0939 | 534 | 0.836 | 78.23 | 21.02 | 2 | 0.0733 | 205 | 0.0014 | 24.71 | 6.757 | 0.2480 | 296615.0 | 170000000 | 100000000000 | 60500000000000 | 0.4327 | 0.2031 | 0.0000 | 0.0000 | 0.0022 | 0.0004 | 0.0017 | 0.0000 | 0.0094 | 0.0007 | 0.0409 | 0.0211 | 0.0819 | 0.0324 | 0.0658 | 0.0200 | 0.0946 | 0.0328 | 0.7035 | 0.8926 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0000 | 0.0039 | 0.0007 | 0.0215 | 0.0211 | 0.0369 | 0.0324 | 0.0292 | 0.0200 | 0.0442 | 0.0298 | 0.8638 | 0.8956 | 0.0019 | 1.0000 | 0.0058 | 0.0000 | 0.0154 | 0.0000 | 0.0288 | 0.0000 | 0.0538 | 0.0000 | 0.1019 | 0.0000 | 0.0596 | 0.0000 | 0.0904 | 0.0000 | 0.6423 | 0.0000 | 0.0021 | 0.0014 | 0.0035 | 0.0174 | 0.0306 | 0.0542 | 0.0480 | 0.0618 | 0.7811 | 3 | 4 | 6 | 7 | 9 | 16 | 32 | 74 | 139 | 0.1144 | 4.30 | 3.672 | 0.6245 | 6558.9 | 1480000 | 411000000 | 131000000000 | 0.3466 | 0.2662 | 0.0039 | 0.0100 | 0.0656 | 0.0116 | 0.1467 | 0.0282 | 0.2625 | 0.0664 | 0.2625 | 0.1678 | 0.1931 | 0.1860 | 0.0618 | 0.1794 | 0.0039 | 0.1910 | 0.0000 | 0.1595 | 0.0006 | 0.0026 | 0.0012 | 0.0037 | 0.0000 | 0.0053 | 0.0078 | 0.0100 | 0.0246 | 0.0238 | 0.0414 | 0.0365 | 0.0402 | 0.0396 | 0.0618 | 0.0497 | 0.8224 | 0.8288 | 0.0000 | 0.0000 | 0.0007 | 0.0015 | 0.0007 | 0.0008 | 0.0092 | 0.0124 | 0.0348 | 0.0372 | 0.0540 | 0.0581 | 0.0511 | 0.0550 | 0.0724 | 0.0790 | 0.7770 | 0.7560 | 0.0000 | 0.0000 | 0.0026 | 0.0059 | 0.0315 | 0.0538 | 0.0446 | 0.0649 | 0.7967 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 307 | 284 | | 4454 | 15705 | 541.8 | 126.10 | 114.66 | 191.51 | 395 | 434 | 463 | 491 | 521 | 551 | 591 | 651 | 728 | 0.0554 | 870 | 1.060 | 102.88 | 27.59 | 2 | 0.0534 | 238 | 0.0008 | 82.33 | 7.369 | 0.1665 | 309466.0 | 186000000 | 118000000000 | 78000000000000 | 0.4066 | 0.2345 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0005 | 0.0157 | 0.0027 | 0.0737 | 0.0261 | 0.1377 | 0.0438 | 0.1448 | 0.0443 | 0.1534 | 0.0597 | 0.4611 | 0.8229 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0056 | 0.0002 | 0.0407 | 0.0161 | 0.0709 | 0.0258 | 0.0709 | 0.0192 | 0.0895 | 0.0269 | 0.7210 | 0.9117 | 0.0022 | 0.0032 | 0.0000 | 0.0160 | 0.0078 | 0.0415 | 0.0526 | 0.0927 | 0.0973 | 0.1629 | 0.1353 | 0.1502 | 0.0839 | 0.1086 | 0.1074 | 0.1438 | 0.5134 | 0.2812 | 0.0000 | 0.0031 | 0.0062 | 0.0333 | 0.0868 | 0.1149 | 0.1004 | 0.1108 | 0.5445 | 5 | 7 | 8 | 10 | 11 | 17 | 98 | 220 | 400 | 0.1818 | 28.75 | 4.115 | 0.6043 | 49820.4 | 29100000 | 19900000000 | 15300000000000 | 0.3528 | 0.2965 | 0.0222 | 0.0027 | 0.0974 | 0.0054 | 0.2530 | 0.0467 | 0.2085 | 0.0916 | 0.1880 | 0.2163 | 0.1333 | 0.2720 | 0.0496 | 0.1517 | 0.0222 | 0.1086 | 0.0256 | 0.1050 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0025 | 0.0028 | 0.0223 | 0.0206 | 0.0377 | 0.0307 | 0.0289 | 0.0256 | 0.0466 | 0.0365 | 0.8607 | 0.8834 | 0.0005 | 0.0003 | 0.0002 | 0.0005 | 0.0002 | 0.0005 | 0.0059 | 0.0071 | 0.0334 | 0.0374 | 0.0541 | 0.0695 | 0.0498 | 0.0450 | 0.0636 | 0.0730 | 0.7923 | 0.7666 | 0.0002 | 0.0000 | 0.0004 | 0.0042 | 0.0271 | 0.0491 | 0.0391 | 0.0560 | 0.8237 | ||
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 580 | 433 | | 1493 | 7000 | 280.3 | 39.92 | 26.94 | 45.70 | 230 | 246 | 259 | 269 | 278 | 289 | 298 | 312 | 333 | 0.0730 | 511 | 0.722 | 72.57 | 16.03 | 1 | 0.1092 | 163 | 0.0044 | 8.62 | 5.687 | 0.3499 | 80150.8 | 23400000 | 6950000000 | 2110000000000 | 0.4223 | 0.2148 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0007 | 0.0385 | 0.0235 | 0.0577 | 0.0450 | 0.0513 | 0.0215 | 0.0810 | 0.0403 | 0.7642 | 0.8690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0007 | 0.0246 | 0.0221 | 0.0377 | 0.0442 | 0.0261 | 0.0181 | 0.0399 | 0.0328 | 0.8681 | 0.8821 | 0.0226 | 0.2000 | 0.0150 | 0.2000 | 0.0526 | 0.4000 | 0.0677 | 0.2000 | 0.0602 | 0.0000 | 0.1053 | 0.0000 | 0.0902 | 0.0000 | 0.1278 | 0.0000 | 0.4586 | 0.0000 | 0.0014 | 0.0014 | 0.0069 | 0.0220 | 0.0495 | 0.0755 | 0.0975 | 0.1319 | 0.6140 | 7 | 8 | 9 | 10 | 12 | 15 | 20 | 33 | 57 | 0.2933 | 1.67 | 2.358 | 0.8342 | 2814.2 | 777978 | 343000000 | 188000000000 | 0.6091 | 0.1098 | 0.0437 | 0.0353 | 0.0542 | 0.0453 | 0.0822 | 0.0637 | 0.1014 | 0.0599 | 0.1294 | 0.0860 | 0.1451 | 0.1083 | 0.1521 | 0.1045 | 0.1573 | 0.1421 | 0.1346 | 0.3548 | 0.0065 | 0.0172 | 0.0101 | 0.0192 | 0.0081 | 0.0204 | 0.0141 | 0.0188 | 0.0252 | 0.0337 | 0.0348 | 0.0425 | 0.0403 | 0.0357 | 0.0685 | 0.0665 | 0.7924 | 0.7459 | 0.0035 | 0.0050 | 0.0042 | 0.0084 | 0.0099 | 0.0168 | 0.0156 | 0.0218 | 0.0453 | 0.0536 | 0.0545 | 0.0662 | 0.0630 | 0.0679 | 0.1288 | 0.1274 | 0.6752 | 0.6329 | 0.0024 | 0.0047 | 0.0082 | 0.0141 | 0.0294 | 0.0500 | 0.0488 | 0.1106 | 0.7318 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 149 | 240 | | 6671 | 12334 | 390.0 | 50.74 | 109.56 | 270.04 | 317 | 352 | 374 | 389 | 399 | 409 | 419 | 431 | 446 | 0.0712 | 878 | 0.700 | 125.40 | 29.61 | 3 | 0.0475 | 317 | 0.0019 | 22.81 | 6.624 | 0.2349 | 154695.0 | 62200000 | 25300000000 | 10400000000000 | 0.4580 | 0.1948 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0037 | 0.0003 | 0.0169 | 0.0112 | 0.0407 | 0.0210 | 0.0412 | 0.0134 | 0.0715 | 0.0187 | 0.8249 | 0.9354 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0003 | 0.0133 | 0.0112 | 0.0316 | 0.0210 | 0.0235 | 0.0134 | 0.0319 | 0.0187 | 0.8969 | 0.9354 | 0.1176 | 0.0000 | 0.1438 | 0.0000 | 0.1373 | 0.0000 | 0.1830 | 0.0000 | 0.1111 | 0.0000 | 0.1569 | 0.0000 | 0.0261 | 0.0000 | 0.0523 | 0.0000 | 0.0719 | 0.0000 | 0.0020 | 0.0033 | 0.0091 | 0.0202 | 0.0463 | 0.0663 | 0.0825 | 0.1189 | 0.6514 | 9 | 11 | 12 | 14 | 15 | 18 | 24 | 59 | 344 | 0.2142 | 6.81 | 2.736 | 0.6641 | 84919.1 | 101000000 | 144000000000 | 229000000000000 | 0.5929 | 0.1077 | 0.0204 | 0.0068 | 0.0980 | 0.0068 | 0.1592 | 0.0492 | 0.1878 | 0.0881 | 0.2082 | 0.1593 | 0.1755 | 0.1864 | 0.1020 | 0.1203 | 0.0367 | 0.1661 | 0.0122 | 0.2169 | 0.0005 | 0.0017 | 0.0019 | 0.0004 | 0.0014 | 0.0034 | 0.0052 | 0.0085 | 0.0331 | 0.0296 | 0.0553 | 0.0525 | 0.0355 | 0.0407 | 0.0766 | 0.0805 | 0.7905 | 0.7827 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0021 | 0.0017 | 0.0064 | 0.0079 | 0.0380 | 0.0350 | 0.0545 | 0.0599 | 0.0401 | 0.0418 | 0.0866 | 0.0870 | 0.7722 | 0.7662 | 0.0000 | 0.0000 | 0.0020 | 0.0076 | 0.0289 | 0.0613 | 0.0370 | 0.0770 | 0.7863 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1217 | 492 | | 4158 | 8748 | 478.3 | 77.87 | 112.81 | 236.09 | 376 | 414 | 441 | 464 | 483 | 499 | 516 | 535 | 574 | 0.0725 | 634 | 0.983 | 79.31 | 27.31 | 1 | 0.0536 | 223 | 0.0016 | 22.49 | 6.757 | 0.2408 | 234837.0 | 118000000 | 60800000000 | 31900000000000 | 0.3975 | 0.2479 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0070 | 0.0005 | 0.0263 | 0.0161 | 0.0444 | 0.0266 | 0.0456 | 0.0159 | 0.0702 | 0.0242 | 0.8058 | 0.9168 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0002 | 0.0174 | 0.0145 | 0.0277 | 0.0252 | 0.0261 | 0.0128 | 0.0397 | 0.0206 | 0.8859 | 0.9267 | 0.0048 | 0.0000 | 0.0048 | 0.0000 | 0.0096 | 0.0556 | 0.0264 | 0.0833 | 0.0769 | 0.1667 | 0.0817 | 0.1389 | 0.1082 | 0.1667 | 0.1034 | 0.1111 | 0.5841 | 0.2778 | 0.0014 | 0.0018 | 0.0063 | 0.0136 | 0.0407 | 0.0678 | 0.0691 | 0.0985 | 0.7010 | 5 | 7 | 8 | 9 | 10 | 12 | 22 | 146 | 413 | 0.1638 | 17.76 | 3.315 | 0.5824 | 68457.9 | 58700000 | 59900000000 | 68200000000000 | 0.3262 | 0.2943 | 0.0588 | 0.0025 | 0.2888 | 0.0296 | 0.2513 | 0.1605 | 0.1016 | 0.1951 | 0.1123 | 0.1975 | 0.0695 | 0.1383 | 0.1016 | 0.0864 | 0.0107 | 0.0963 | 0.0053 | 0.0938 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0005 | 0.0081 | 0.0076 | 0.0389 | 0.0360 | 0.0567 | 0.0536 | 0.0354 | 0.0337 | 0.0445 | 0.0469 | 0.8164 | 0.8208 | 0.0006 | 0.0006 | 0.0000 | 0.0012 | 0.0045 | 0.0041 | 0.0078 | 0.0088 | 0.0380 | 0.0364 | 0.0553 | 0.0634 | 0.0330 | 0.0346 | 0.0508 | 0.0511 | 0.8101 | 0.7999 | 0.0000 | 0.0000 | 0.0005 | 0.0123 | 0.0410 | 0.0511 | 0.0373 | 0.0453 | 0.8125 | ||
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 350 | 768 | | 2148 | 7377 | 649.8 | 190.42 | 59.61 | 108.11 | 361 | 467 | 544 | 624 | 689 | 729 | 767 | 811 | 863 | 0.0729 | 538 | 0.439 | 61.06 | 9.22 | 3 | 0.0791 | 170 | 0.0009 | 72.75 | 7.161 | 0.1651 | 458473.0 | 344000000 | 270000000000 | 221000000000000 | 0.4160 | 0.2058 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0006 | 0.0291 | 0.0023 | 0.0824 | 0.0283 | 0.1568 | 0.0702 | 0.1075 | 0.0385 | 0.1397 | 0.0645 | 0.4794 | 0.7957 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0016 | 0.0293 | 0.0240 | 0.0560 | 0.0464 | 0.0350 | 0.0235 | 0.0592 | 0.0427 | 0.8160 | 0.8617 | 0.0000 | 0.0094 | 0.0000 | 0.0283 | 0.0035 | 0.0189 | 0.0260 | 0.0566 | 0.0781 | 0.1415 | 0.1163 | 0.2264 | 0.0885 | 0.0472 | 0.1250 | 0.1038 | 0.5625 | 0.3679 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0432 | 0.0639 | 0.0490 | 0.0763 | 0.7585 | 7 | 9 | 11 | 13 | 16 | 21 | 32 | 64 | 203 | 0.0746 | 10.49 | 3.983 | 0.6307 | 15239.4 | 6560000 | 3660000000 | 2420000000000 | 0.2920 | 0.3302 | 0.0000 | 0.0050 | 0.0655 | 0.0113 | 0.2143 | 0.0239 | 0.2292 | 0.0642 | 0.2054 | 0.1597 | 0.1429 | 0.2013 | 0.0774 | 0.1660 | 0.0506 | 0.1698 | 0.0149 | 0.1987 | 0.0000 | 0.0019 | 0.0017 | 0.0043 | 0.0040 | 0.0038 | 0.0115 | 0.0125 | 0.0340 | 0.0355 | 0.0530 | 0.0485 | 0.0363 | 0.0384 | 0.0594 | 0.0677 | 0.8000 | 0.7872 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0031 | 0.0129 | 0.0109 | 0.0372 | 0.0427 | 0.0558 | 0.0637 | 0.0393 | 0.0365 | 0.0629 | 0.0637 | 0.7877 | 0.7793 | 0.0000 | 0.0000 | 0.0007 | 0.0170 | 0.0352 | 0.0483 | 0.0463 | 0.0614 | 0.7911 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1026 | 526 | | 1774 | 10377 | 333.7 | 82.77 | 7.07 | 6.95 | 228 | 252 | 275 | 299 | 328 | 356 | 381 | 404 | 456 | 0.0754 | 782 | 1.019 | 63.03 | 17.72 | 1 | 0.0902 | 160 | 0.0074 | 2.20 | 5.116 | 0.5219 | 118176.0 | 44200000 | 17400000000 | 7100000000000 | 0.3704 | 0.2523 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0044 | 0.0018 | 0.0196 | 0.0031 | 0.0480 | 0.0270 | 0.0981 | 0.0590 | 0.0960 | 0.0277 | 0.1156 | 0.0522 | 0.6161 | 0.8291 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0006 | 0.0077 | 0.0006 | 0.0216 | 0.0198 | 0.0448 | 0.0475 | 0.0309 | 0.0158 | 0.0394 | 0.0300 | 0.8533 | 0.8858 | 0.0000 | 0.0070 | 0.0026 | 0.0000 | 0.0159 | 0.0211 | 0.0265 | 0.0493 | 0.0688 | 0.0563 | 0.0688 | 0.0634 | 0.0794 | 0.1197 | 0.0926 | 0.1127 | 0.6455 | 0.5704 | 0.0000 | 0.0012 | 0.0035 | 0.0106 | 0.0307 | 0.0507 | 0.0460 | 0.0507 | 0.8066 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.0683 | 0.36 | 0.960 | 0.2803 | 98.4 | 3645.61 | 211535 | 13700000 | 0.5870 | 0.1077 | 0.0219 | 0.0000 | 0.0918 | 0.0034 | 0.2036 | 0.0218 | 0.2478 | 0.0615 | 0.2315 | 0.1441 | 0.1344 | 0.2346 | 0.0524 | 0.2632 | 0.0151 | 0.1992 | 0.0014 | 0.0723 | 0.0070 | 0.0001 | 0.0372 | 0.0017 | 0.1009 | 0.0115 | 0.1433 | 0.0351 | 0.1866 | 0.1006 | 0.1797 | 0.1701 | 0.1357 | 0.2256 | 0.0991 | 0.2326 | 0.1105 | 0.2226 | 0.2165 | 0.2377 | 0.1957 | 0.1575 | 0.1447 | 0.1137 | 0.0919 | 0.0699 | 0.0705 | 0.0657 | 0.0566 | 0.0428 | 0.0334 | 0.0323 | 0.0340 | 0.0396 | 0.1567 | 0.2409 | 0.0252 | 0.0972 | 0.1538 | 0.1674 | 0.1709 | 0.1299 | 0.1019 | 0.0664 | 0.0874 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 372 | 139 | | 4417 | 11190 | 35.9 | 14.42 | 6.81 | 2.68 | 18 | 23 | 27 | 31 | 35 | 38 | 42 | 47 | 55 | 0.1108 | 1240 | 0.972 | 96.52 | 27.73 | 0 | 0.0541 | 239 | 0.0016 | 19.80 | 6.657 | 0.2399 | 1496.0 | 70708.7 | 3720000 | 215000000 | 0.3566 | 0.2612 | 0.0074 | 0.0033 | 0.0138 | 0.0046 | 0.0275 | 0.0100 | 0.0401 | 0.0219 | 0.0682 | 0.0306 | 0.1181 | 0.0604 | 0.1456 | 0.0764 | 0.2189 | 0.1249 | 0.3605 | 0.6679 | 0.0027 | 0.0016 | 0.0044 | 0.0025 | 0.0061 | 0.0041 | 0.0123 | 0.0106 | 0.0194 | 0.0144 | 0.0310 | 0.0289 | 0.0358 | 0.0324 | 0.0607 | 0.0501 | 0.8275 | 0.8554 | 0.0135 | 0.0136 | 0.0143 | 0.0303 | 0.0236 | 0.0394 | 0.0412 | 0.0455 | 0.0648 | 0.0636 | 0.0732 | 0.0924 | 0.0875 | 0.1030 | 0.1052 | 0.1288 | 0.5766 | 0.4833 | 0.0024 | 0.0118 | 0.0142 | 0.0217 | 0.0307 | 0.0558 | 0.0728 | 0.1281 | 0.6626 | 3 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0130 | 14.88 | 4.690 | 0.2835 | 53.5 | 466.389 | 4418.91 | 44994.1 | 0.5386 | 0.1220 | 0.0193 | 0.0018 | 0.0771 | 0.0147 | 0.1782 | 0.0531 | 0.2352 | 0.1151 | 0.2415 | 0.1932 | 0.1553 | 0.2539 | 0.0676 | 0.2164 | 0.0219 | 0.1202 | 0.0039 | 0.0316 | 0.0009 | 0.0001 | 0.0099 | 0.0021 | 0.0376 | 0.0123 | 0.0944 | 0.0380 | 0.1707 | 0.0873 | 0.2304 | 0.1689 | 0.2167 | 0.2533 | 0.1681 | 0.2793 | 0.0711 | 0.1586 | 0.1499 | 0.2801 | 0.2687 | 0.3198 | 0.2320 | 0.2121 | 0.1617 | 0.1088 | 0.0909 | 0.0480 | 0.0568 | 0.0201 | 0.0279 | 0.0084 | 0.0099 | 0.0022 | 0.0022 | 0.0006 | 0.0072 | 0.0437 | 0.1150 | 0.1799 | 0.2208 | 0.1990 | 0.1331 | 0.0731 | 0.0283 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1205 | 176 | | 372 | 2800 | 40.2 | 10.05 | 84.88 | 173.91 | 28 | 30 | 34 | 37 | 39 | 41 | 45 | 49 | 53 | 0.1139 | 319 | 0.581 | 191.64 | 52.00 | 2 | 1.5618 | 581 | 0.0086 | 8.20 | 4.933 | 0.3440 | 1713.9 | 77670.5 | 3730000 | 189000000 | 0.3953 | 0.2248 | 0.0051 | 0.0000 | 0.0154 | 0.0000 | 0.0359 | 0.0000 | 0.1333 | 0.0088 | 0.1744 | 0.0821 | 0.1897 | 0.0645 | 0.2154 | 0.1026 | 0.1333 | 0.1378 | 0.0974 | 0.6041 | 0.0036 | 0.0000 | 0.0108 | 0.0000 | 0.0108 | 0.0000 | 0.0502 | 0.0054 | 0.0681 | 0.0622 | 0.0681 | 0.0514 | 0.0968 | 0.0514 | 0.1147 | 0.0784 | 0.5771 | 0.7514 | 0.0000 | 0.0000 | 0.0357 | 0.0345 | 0.1190 | 0.0690 | 0.0238 | 0.2069 | 0.1786 | 0.1379 | 0.1667 | 0.0345 | 0.0952 | 0.2069 | 0.1548 | 0.1379 | 0.2262 | 0.1724 | 0.0056 | 0.0056 | 0.0222 | 0.0444 | 0.0778 | 0.0944 | 0.0889 | 0.1778 | 0.4833 | 15 | 17 | 19 | 21 | 23 | 27 | 32 | 79 | 241 | 0.2089 | 3.35 | 2.782 | 0.7521 | 37440.5 | 29600000 | 28700000000 | 30700000000000 | 0.7152 | 0.0493 | 0.0130 | 0.0061 | 0.1299 | 0.0242 | 0.2987 | 0.0242 | 0.1948 | 0.0848 | 0.1429 | 0.2061 | 0.0779 | 0.2485 | 0.0649 | 0.1333 | 0.0260 | 0.1455 | 0.0519 | 0.1273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0120 | 0.0126 | 0.0342 | 0.0346 | 0.0496 | 0.0362 | 0.0479 | 0.0472 | 0.0803 | 0.0849 | 0.7761 | 0.7799 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0021 | 0.0138 | 0.0085 | 0.0472 | 0.0446 | 0.0591 | 0.0807 | 0.0571 | 0.0573 | 0.1004 | 0.1083 | 0.7185 | 0.6985 | 0.0000 | 0.0000 | 0.0018 | 0.0091 | 0.0453 | 0.0507 | 0.0562 | 0.0888 | 0.7482 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1199 | 461 | | 4972 | 6147 | 193.3 | 101.39 | 92.03 | 198.27 | 86 | 103 | 120 | 137 | 155 | 189 | 252 | 298 | 348 | 0.1223 | 752 | 0.646 | 151.35 | 28.23 | 6 | 0.0686 | 341 | 0.0019 | 14.93 | 6.742 | 0.3352 | 47639.3 | 13900000 | 4520000000 | 1570000000000 | 0.3496 | 0.2649 | 0.0060 | 0.0004 | 0.0048 | 0.0035 | 0.0132 | 0.0052 | 0.0396 | 0.0148 | 0.1321 | 0.0461 | 0.2233 | 0.0804 | 0.1417 | 0.0722 | 0.1573 | 0.1039 | 0.2821 | 0.6735 | 0.0016 | 0.0003 | 0.0016 | 0.0017 | 0.0036 | 0.0011 | 0.0084 | 0.0058 | 0.0244 | 0.0172 | 0.0407 | 0.0302 | 0.0339 | 0.0266 | 0.0395 | 0.0388 | 0.8462 | 0.8784 | 0.0000 | 0.0008 | 0.0006 | 0.0015 | 0.0012 | 0.0061 | 0.0096 | 0.0107 | 0.0215 | 0.0313 | 0.0413 | 0.0595 | 0.0311 | 0.0489 | 0.0431 | 0.0794 | 0.8516 | 0.7618 | 0.0005 | 0.0000 | 0.0005 | 0.0046 | 0.0245 | 0.0408 | 0.0245 | 0.0362 | 0.8684 | 6 | 7 | 9 | 10 | 13 | 18 | 35 | 93 | 274 | 0.1539 | 10.11 | 3.626 | 0.6621 | 47772.6 | 36200000 | 31300000000 | 29200000000000 | 0.4667 | 0.1877 | 0.0120 | 0.0059 | 0.0518 | 0.0098 | 0.1076 | 0.0234 | 0.1992 | 0.0508 | 0.2231 | 0.1484 | 0.1673 | 0.2266 | 0.0916 | 0.1348 | 0.0598 | 0.1465 | 0.0876 | 0.2539 | 0.0007 | 0.0013 | 0.0036 | 0.0026 | 0.0051 | 0.0078 | 0.0182 | 0.0156 | 0.0547 | 0.0591 | 0.0591 | 0.0604 | 0.0562 | 0.0558 | 0.0795 | 0.0734 | 0.7228 | 0.7240 | 0.0000 | 0.0010 | 0.0063 | 0.0019 | 0.0063 | 0.0039 | 0.0116 | 0.0068 | 0.0634 | 0.0623 | 0.0598 | 0.0700 | 0.0625 | 0.0623 | 0.0938 | 0.0944 | 0.6964 | 0.6975 | 0.0008 | 0.0041 | 0.0081 | 0.0122 | 0.0575 | 0.0632 | 0.0624 | 0.0875 | 0.7042 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 173 | 580 | | 3314 | 11955 | 517.2 | 91.88 | 119.57 | 243.85 | 373 | 433 | 487 | 512 | 531 | 550 | 573 | 598 | 624 | 0.0613 | 733 | 0.446 | 104.39 | 23.32 | 3 | 0.0993 | 329 | 0.0010 | 41.90 | 7.124 | 0.2030 | 275939.0 | 151000000 | 84400000000 | 48000000000000 | 0.4375 | 0.1965 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0017 | 0.0003 | 0.0071 | 0.0009 | 0.0384 | 0.0163 | 0.0744 | 0.0359 | 0.0660 | 0.0157 | 0.0994 | 0.0273 | 0.7101 | 0.9033 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0000 | 0.0003 | 0.0014 | 0.0009 | 0.0206 | 0.0163 | 0.0343 | 0.0359 | 0.0220 | 0.0157 | 0.0354 | 0.0273 | 0.8851 | 0.9033 | 0.0134 | 0.0000 | 0.0160 | 0.0000 | 0.0428 | 0.0000 | 0.0856 | 0.0000 | 0.1096 | 0.0000 | 0.1791 | 0.0000 | 0.1123 | 0.0000 | 0.1417 | 0.0000 | 0.2995 | 0.0000 | 0.0005 | 0.0042 | 0.0094 | 0.0141 | 0.0381 | 0.0522 | 0.0637 | 0.0914 | 0.7262 | 9 | 12 | 14 | 16 | 21 | 31 | 57 | 130 | 371 | 0.1465 | 4.98 | 3.299 | 0.6421 | 73753.8 | 72700000 | 87000000000 | 116000000000000 | 0.4905 | 0.1557 | 0.0398 | 0.0000 | 0.1155 | 0.0121 | 0.1474 | 0.0864 | 0.1932 | 0.1021 | 0.1972 | 0.1690 | 0.1554 | 0.1820 | 0.0777 | 0.1328 | 0.0498 | 0.1235 | 0.0239 | 0.1922 | 0.0000 | 0.0000 | 0.0025 | 0.0012 | 0.0051 | 0.0044 | 0.0108 | 0.0097 | 0.0375 | 0.0400 | 0.0563 | 0.0512 | 0.0512 | 0.0465 | 0.0776 | 0.0787 | 0.7589 | 0.7684 | 0.0000 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0028 | 0.0119 | 0.0127 | 0.0419 | 0.0409 | 0.0608 | 0.0682 | 0.0591 | 0.0564 | 0.0784 | 0.0804 | 0.7466 | 0.7377 | 0.0008 | 0.0008 | 0.0028 | 0.0097 | 0.0399 | 0.0565 | 0.0480 | 0.0871 | 0.7543 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 332 | 897 | | 4130 | 6420 | 525.0 | 190.33 | 45.50 | 77.20 | 256 | 314 | 388 | 474 | 542 | 599 | 659 | 716 | 767 | 0.1092 | 701 | 0.638 | 84.10 | 14.14 | 5 | 0.0482 | 199 | 0.0007 | 53.48 | 7.439 | 0.1929 | 311857.0 | 201000000 | 138000000000 | 98300000000000 | 0.3906 | 0.2301 | 0.0000 | 0.0015 | 0.0031 | 0.0011 | 0.0168 | 0.0011 | 0.0291 | 0.0083 | 0.1034 | 0.0496 | 0.1516 | 0.0931 | 0.1309 | 0.0644 | 0.1072 | 0.0966 | 0.4579 | 0.6842 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0018 | 0.0328 | 0.0255 | 0.0470 | 0.0436 | 0.0303 | 0.0252 | 0.0445 | 0.0370 | 0.8418 | 0.8670 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0021 | 0.0167 | 0.0104 | 0.0410 | 0.0494 | 0.0819 | 0.0626 | 0.1335 | 0.0494 | 0.1108 | 0.0745 | 0.1457 | 0.7516 | 0.4643 | 0.0000 | 0.0005 | 0.0005 | 0.0045 | 0.0352 | 0.0587 | 0.0352 | 0.0564 | 0.8090 | 8 | 10 | 13 | 15 | 17 | 22 | 31 | 60 | 119 | 0.0622 | 10.67 | 3.904 | 0.6364 | 8028.7 | 3400000 | 2280000000 | 1870000000000 | 0.5362 | 0.1440 | 0.0369 | 0.0169 | 0.0844 | 0.0226 | 0.1082 | 0.0463 | 0.1504 | 0.0993 | 0.1847 | 0.1366 | 0.1821 | 0.1061 | 0.1372 | 0.1163 | 0.0976 | 0.1558 | 0.0185 | 0.3002 | 0.0017 | 0.0057 | 0.0034 | 0.0076 | 0.0040 | 0.0086 | 0.0115 | 0.0195 | 0.0453 | 0.0437 | 0.0539 | 0.0518 | 0.0441 | 0.0456 | 0.0648 | 0.0699 | 0.7713 | 0.7476 | 0.0007 | 0.0025 | 0.0029 | 0.0016 | 0.0102 | 0.0074 | 0.0154 | 0.0164 | 0.0469 | 0.0402 | 0.0608 | 0.0731 | 0.0490 | 0.0484 | 0.0791 | 0.0649 | 0.7350 | 0.7455 | 0.0006 | 0.0051 | 0.0058 | 0.0135 | 0.0398 | 0.0630 | 0.0424 | 0.0694 | 0.7603 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 854 | 416 | | 11131 | 15417 | 454.3 | 71.88 | 90.38 | 157.98 | 358 | 393 | 418 | 438 | 454 | 468 | 484 | 508 | 549 | 0.0688 | 1061 | 1.159 | 147.22 | 49.48 | 2 | 0.0314 | 350 | 0.0013 | 17.13 | 6.964 | 0.2615 | 211570.0 | 101000000 | 49300000000 | 24600000000000 | 0.4019 | 0.2435 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0025 | 0.0005 | 0.0056 | 0.0007 | 0.0198 | 0.0107 | 0.0364 | 0.0188 | 0.0370 | 0.0124 | 0.0542 | 0.0178 | 0.8429 | 0.9388 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0023 | 0.0002 | 0.0110 | 0.0093 | 0.0213 | 0.0169 | 0.0198 | 0.0089 | 0.0278 | 0.0138 | 0.9153 | 0.9509 | 0.0058 | 0.0159 | 0.0075 | 0.0397 | 0.0100 | 0.0556 | 0.0325 | 0.1270 | 0.0600 | 0.0873 | 0.0783 | 0.1349 | 0.0666 | 0.1111 | 0.0966 | 0.0952 | 0.6428 | 0.3333 | 0.0012 | 0.0023 | 0.0068 | 0.0178 | 0.0371 | 0.0570 | 0.0697 | 0.0892 | 0.7189 | 7 | 9 | 10 | 11 | 14 | 23 | 53 | 139 | 311 | 0.2296 | 12.11 | 3.590 | 0.7091 | 33126.6 | 17600000 | 11100000000 | 7920000000000 | 0.5835 | 0.1060 | 0.0228 | 0.0066 | 0.0791 | 0.0185 | 0.1263 | 0.0524 | 0.1948 | 0.0739 | 0.1933 | 0.1344 | 0.1522 | 0.1839 | 0.0898 | 0.1440 | 0.0883 | 0.1322 | 0.0533 | 0.2541 | 0.0000 | 0.0006 | 0.0012 | 0.0017 | 0.0021 | 0.0039 | 0.0062 | 0.0067 | 0.0321 | 0.0323 | 0.0482 | 0.0424 | 0.0349 | 0.0336 | 0.0634 | 0.0528 | 0.8120 | 0.8259 | 0.0011 | 0.0003 | 0.0031 | 0.0018 | 0.0025 | 0.0028 | 0.0098 | 0.0104 | 0.0419 | 0.0429 | 0.0613 | 0.0726 | 0.0526 | 0.0643 | 0.0793 | 0.0867 | 0.7482 | 0.7182 | 0.0003 | 0.0013 | 0.0028 | 0.0103 | 0.0339 | 0.0573 | 0.0419 | 0.0637 | 0.7885 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 582 | 250 | | 4778 | 14966 | 457.7 | 96.53 | 89.22 | 140.57 | 342 | 375 | 399 | 423 | 446 | 472 | 503 | 544 | 595 | 0.0565 | 845 | 1.104 | 103.97 | 26.91 | 1 | 0.0479 | 229 | 0.0010 | 47.20 | 7.130 | 0.1892 | 218847.0 | 109000000 | 56500000000 | 30300000000000 | 0.4000 | 0.2511 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0045 | 0.0004 | 0.0175 | 0.0009 | 0.0684 | 0.0206 | 0.1267 | 0.0402 | 0.1305 | 0.0356 | 0.1626 | 0.0566 | 0.4879 | 0.8457 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0048 | 0.0004 | 0.0342 | 0.0151 | 0.0585 | 0.0274 | 0.0650 | 0.0193 | 0.0849 | 0.0278 | 0.7521 | 0.9101 | 0.0078 | 0.0314 | 0.0045 | 0.0314 | 0.0201 | 0.0419 | 0.0536 | 0.0576 | 0.1095 | 0.2042 | 0.1430 | 0.1937 | 0.1128 | 0.1152 | 0.1296 | 0.1571 | 0.4190 | 0.1675 | 0.0018 | 0.0041 | 0.0115 | 0.0290 | 0.0809 | 0.1241 | 0.0938 | 0.1159 | 0.5389 | 5 | 7 | 8 | 10 | 12 | 21 | 71 | 181 | 309 | 0.1594 | 14.47 | 4.050 | 0.6108 | 27717.5 | 11400000 | 5320000000 | 2730000000000 | 0.4192 | 0.2070 | 0.0600 | 0.0054 | 0.1989 | 0.0109 | 0.2420 | 0.0827 | 0.1839 | 0.1544 | 0.1407 | 0.2452 | 0.0882 | 0.1962 | 0.0563 | 0.0990 | 0.0169 | 0.0990 | 0.0131 | 0.1072 | 0.0002 | 0.0002 | 0.0007 | 0.0002 | 0.0009 | 0.0008 | 0.0083 | 0.0087 | 0.0333 | 0.0322 | 0.0492 | 0.0453 | 0.0395 | 0.0316 | 0.0572 | 0.0465 | 0.8108 | 0.8345 | 0.0000 | 0.0005 | 0.0018 | 0.0005 | 0.0025 | 0.0013 | 0.0079 | 0.0070 | 0.0370 | 0.0436 | 0.0631 | 0.0662 | 0.0484 | 0.0554 | 0.0667 | 0.0759 | 0.7725 | 0.7495 | 0.0000 | 0.0000 | 0.0019 | 0.0086 | 0.0378 | 0.0557 | 0.0431 | 0.0633 | 0.7896 | ||
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 886 | 459 | | 3618 | 10342 | 579.4 | 120.00 | 16.41 | 14.61 | 402 | 502 | 541 | 570 | 596 | 621 | 644 | 667 | 707 | 0.0617 | 638 | 0.872 | 72.47 | 21.02 | 4 | 0.0506 | 183 | 0.0010 | 57.19 | 7.152 | 0.1994 | 350122.0 | 218000000 | 140000000000 | 91900000000000 | 0.4429 | 0.2126 | 0.0004 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0006 | 0.0086 | 0.0012 | 0.0409 | 0.0173 | 0.0601 | 0.0352 | 0.0530 | 0.0212 | 0.0823 | 0.0391 | 0.7539 | 0.8852 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0013 | 0.0009 | 0.0167 | 0.0167 | 0.0279 | 0.0301 | 0.0196 | 0.0140 | 0.0382 | 0.0289 | 0.8963 | 0.9084 | 0.0088 | 0.0000 | 0.0044 | 0.0980 | 0.0199 | 0.0000 | 0.0508 | 0.0980 | 0.1258 | 0.1569 | 0.1523 | 0.1765 | 0.1192 | 0.0588 | 0.1501 | 0.1373 | 0.3687 | 0.2745 | 0.0000 | 0.0005 | 0.0063 | 0.0146 | 0.0466 | 0.0777 | 0.0670 | 0.0869 | 0.7005 | 6 | 8 | 9 | 11 | 13 | 15 | 17 | 20 | 29 | 0.2798 | 0.41 | 1.932 | 0.8610 | 482.7 | 28156.6 | 2820000 | 388000000 | 0.4309 | 0.2072 | 0.0435 | 0.0205 | 0.0470 | 0.0372 | 0.0509 | 0.0455 | 0.0895 | 0.0516 | 0.1126 | 0.0612 | 0.1545 | 0.0846 | 0.2073 | 0.1008 | 0.1905 | 0.1706 | 0.1043 | 0.4280 | 0.0225 | 0.0151 | 0.0206 | 0.0257 | 0.0213 | 0.0301 | 0.0324 | 0.0319 | 0.0506 | 0.0421 | 0.0689 | 0.0635 | 0.0845 | 0.0648 | 0.1386 | 0.1026 | 0.5606 | 0.6242 | 0.0382 | 0.0267 | 0.0326 | 0.0130 | 0.0336 | 0.0298 | 0.0424 | 0.0360 | 0.0559 | 0.0477 | 0.0634 | 0.0701 | 0.0662 | 0.0775 | 0.1058 | 0.0967 | 0.5620 | 0.6026 | 0.0209 | 0.0300 | 0.0386 | 0.0551 | 0.0695 | 0.0973 | 0.0921 | 0.1086 | 0.4879 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 688 | 724 | | 382 | 3170 | 111.2 | 49.61 | 43.27 | 125.08 | 45 | 55 | 71 | 91 | 111 | 133 | 151 | 163 | 177 | 0.1344 | 426 | 0.422 | 253.34 | 46.17 | 1 | 2.3037 | 880 | 0.0037 | 31.49 | 5.680 | 0.1888 | 14813.4 | 2190000 | 345000000 | 56300000000 | 0.2747 | 0.3491 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.2262 | 0.0345 | 0.3929 | 0.1379 | 0.2857 | 0.2184 | 0.0357 | 0.1494 | 0.0595 | 0.2184 | 0.0000 | 0.2356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0072 | 0.0681 | 0.0578 | 0.0851 | 0.0866 | 0.0511 | 0.0433 | 0.0681 | 0.0650 | 0.7191 | 0.7401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0194 | 0.0927 | 0.1553 | 0.1192 | 0.1165 | 0.0397 | 0.0971 | 0.1060 | 0.1165 | 0.6424 | 0.4854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0733 | 0.1257 | 0.0314 | 0.0733 | 0.6963 | 7 | 8 | 9 | 10 | 10 | 11 | 12 | 15 | 33 | 0.6117 | 5.34 | 1.436 | 0.8850 | 17511.8 | 11000000 | 7740000000 | 5940000000000 | 0.6927 | 0.0495 | 0.0357 | 0.0000 | 0.1429 | 0.0385 | 0.2857 | 0.0641 | 0.2143 | 0.1538 | 0.1786 | 0.2436 | 0.1429 | 0.1923 | 0.0000 | 0.1154 | 0.0000 | 0.1538 | 0.0000 | 0.0385 | 0.0032 | 0.0000 | 0.0064 | 0.0085 | 0.0064 | 0.0141 | 0.0129 | 0.0226 | 0.0386 | 0.0621 | 0.0611 | 0.0424 | 0.0675 | 0.0621 | 0.0868 | 0.1017 | 0.7170 | 0.6864 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0035 | 0.0000 | 0.0106 | 0.0181 | 0.0565 | 0.0471 | 0.0636 | 0.0870 | 0.0777 | 0.0725 | 0.0777 | 0.0725 | 0.7102 | 0.6993 | 0.0000 | 0.0000 | 0.0068 | 0.0102 | 0.0476 | 0.0612 | 0.0714 | 0.0884 | 0.7143 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1103 | 517 | | 8577 | 27567 | 251.0 | 73.86 | 67.12 | 106.49 | 158 | 187 | 212 | 231 | 249 | 269 | 291 | 317 | 347 | 0.0463 | 1277 | 0.999 | 61.74 | 14.87 | 3 | 0.0160 | 137 | 0.0006 | 49.24 | 7.634 | 0.1718 | 68432.9 | 19900000 | 6110000000 | 1960000000000 | 0.3917 | 0.2259 | 0.0010 | 0.0000 | 0.0014 | 0.0003 | 0.0060 | 0.0008 | 0.0247 | 0.0042 | 0.0651 | 0.0238 | 0.1257 | 0.0510 | 0.1228 | 0.0509 | 0.1551 | 0.0690 | 0.4982 | 0.8000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0003 | 0.0051 | 0.0018 | 0.0196 | 0.0121 | 0.0368 | 0.0218 | 0.0312 | 0.0145 | 0.0510 | 0.0223 | 0.8549 | 0.9273 | 0.0009 | 0.0040 | 0.0027 | 0.0132 | 0.0085 | 0.0238 | 0.0330 | 0.0886 | 0.0884 | 0.1799 | 0.1152 | 0.1786 | 0.1134 | 0.1310 | 0.1321 | 0.1481 | 0.5058 | 0.2328 | 0.0000 | 0.0028 | 0.0057 | 0.0164 | 0.0375 | 0.0805 | 0.0705 | 0.0898 | 0.6967 | 11 | 13 | 15 | 16 | 19 | 25 | 41 | 93 | 211 | 0.0930 | 8.04 | 3.824 | 0.6491 | 15845.6 | 5950000 | 2770000000 | 1510000000000 | 0.3766 | 0.2478 | 0.0298 | 0.0054 | 0.1067 | 0.0172 | 0.1592 | 0.0551 | 0.1827 | 0.1063 | 0.1820 | 0.1529 | 0.1451 | 0.1722 | 0.0871 | 0.1411 | 0.0659 | 0.1368 | 0.0416 | 0.2130 | 0.0004 | 0.0016 | 0.0017 | 0.0028 | 0.0045 | 0.0051 | 0.0117 | 0.0126 | 0.0354 | 0.0330 | 0.0450 | 0.0458 | 0.0377 | 0.0407 | 0.0557 | 0.0508 | 0.8078 | 0.8077 | 0.0000 | 0.0009 | 0.0007 | 0.0011 | 0.0037 | 0.0022 | 0.0114 | 0.0125 | 0.0389 | 0.0441 | 0.0647 | 0.0648 | 0.0431 | 0.0544 | 0.0638 | 0.0722 | 0.7737 | 0.7478 | 0.0011 | 0.0011 | 0.0023 | 0.0107 | 0.0370 | 0.0558 | 0.0367 | 0.0655 | 0.7899 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 766 | 509 | | 21316 | 24107 | 152.8 | 47.18 | 163.56 | 211.64 | 92 | 112 | 127 | 140 | 153 | 165 | 177 | 192 | 213 | 0.1036 | 2498 | 0.827 | 32.25 | 8.06 | 7 | 0.0040 | 86 | 0.0005 | 77.74 | 7.966 | 0.1418 | 25560.0 | 4600000 | 879000000 | 178000000000 | 0.4877 | 0.1525 | 0.0009 | 0.0000 | 0.0037 | 0.0002 | 0.0149 | 0.0010 | 0.0428 | 0.0072 | 0.1047 | 0.0330 | 0.1809 | 0.0736 | 0.1588 | 0.0762 | 0.1780 | 0.0986 | 0.3152 | 0.7103 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0020 | 0.0004 | 0.0097 | 0.0036 | 0.0325 | 0.0180 | 0.0642 | 0.0375 | 0.0588 | 0.0332 | 0.0797 | 0.0428 | 0.7519 | 0.8643 | 0.0029 | 0.0050 | 0.0051 | 0.0208 | 0.0156 | 0.0337 | 0.0478 | 0.0972 | 0.1088 | 0.1622 | 0.1603 | 0.2009 | 0.1202 | 0.1275 | 0.1473 | 0.1314 | 0.3919 | 0.2212 | 0.0008 | 0.0017 | 0.0048 | 0.0220 | 0.0553 | 0.0994 | 0.0941 | 0.1118 | 0.6100 | 16 | 20 | 29 | 40 | 58 | 89 | 164 | 305 | 506 | 0.0680 | 12.41 | 4.640 | 0.6115 | 71539.6 | 42800000 | 29400000000 | 22000000000000 | 0.5538 | 0.1336 | 0.0351 | 0.0046 | 0.1280 | 0.0167 | 0.2120 | 0.0578 | 0.1783 | 0.0940 | 0.1652 | 0.1624 | 0.1225 | 0.1970 | 0.0736 | 0.1265 | 0.0427 | 0.1262 | 0.0427 | 0.2147 | 0.0004 | 0.0008 | 0.0014 | 0.0014 | 0.0027 | 0.0031 | 0.0150 | 0.0104 | 0.0386 | 0.0411 | 0.0622 | 0.0561 | 0.0522 | 0.0433 | 0.0703 | 0.0687 | 0.7572 | 0.7752 | 0.0009 | 0.0010 | 0.0030 | 0.0044 | 0.0068 | 0.0054 | 0.0149 | 0.0123 | 0.0452 | 0.0465 | 0.0647 | 0.0707 | 0.0588 | 0.0625 | 0.0807 | 0.0936 | 0.7250 | 0.7037 | 0.0003 | 0.0026 | 0.0046 | 0.0144 | 0.0427 | 0.0684 | 0.0512 | 0.0708 | 0.7451 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 |