High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1003 | 529 | | 2853 | 9441 | 157.4 | 32.63 | 102.01 | 102.33 | 118 | 129 | 138 | 146 | 154 | 163 | 173 | 186 | 203 | 0.0660 | 623 | 0.979 | 160.03 | 54.33 | 2 | 0.1497 | 427 | 0.0019 | 22.36 | 6.477 | 0.2304 | 25843.1 | 4420000 | 785000000 | 145000000000 | 0.4460 | 0.2072 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0192 | 0.0004 | 0.0719 | 0.0167 | 0.1561 | 0.0452 | 0.1556 | 0.0440 | 0.1859 | 0.0766 | 0.4081 | 0.8172 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0079 | 0.0004 | 0.0339 | 0.0128 | 0.0715 | 0.0313 | 0.0619 | 0.0174 | 0.0983 | 0.0366 | 0.7251 | 0.9015 | 0.0058 | 0.0182 | 0.0136 | 0.0636 | 0.0312 | 0.1091 | 0.0546 | 0.1364 | 0.1598 | 0.2091 | 0.1598 | 0.1636 | 0.1326 | 0.1091 | 0.1501 | 0.0727 | 0.2924 | 0.1182 | 0.0022 | 0.0022 | 0.0082 | 0.0461 | 0.0848 | 0.1413 | 0.1048 | 0.1361 | 0.4743 | 11 | 16 | 29 | 45 | 66 | 93 | 129 | 176 | 245 | 0.0152 | 19.08 | 5.619 | 0.4258 | 20875.8 | 5920000 | 2050000000 | 824000000000 | 0.6242 | 0.0881 | 0.0390 | 0.0034 | 0.1453 | 0.0111 | 0.2356 | 0.0610 | 0.1887 | 0.1245 | 0.1532 | 0.1987 | 0.1098 | 0.1906 | 0.0691 | 0.1394 | 0.0452 | 0.1275 | 0.0142 | 0.1437 | 0.0005 | 0.0002 | 0.0017 | 0.0008 | 0.0036 | 0.0041 | 0.0167 | 0.0119 | 0.0708 | 0.0582 | 0.1106 | 0.0877 | 0.0886 | 0.0769 | 0.1254 | 0.1103 | 0.5821 | 0.6499 | 0.0013 | 0.0008 | 0.0027 | 0.0032 | 0.0103 | 0.0122 | 0.0279 | 0.0363 | 0.0920 | 0.1137 | 0.1411 | 0.1512 | 0.1159 | 0.1204 | 0.1388 | 0.1524 | 0.4699 | 0.4098 | 0.0011 | 0.0034 | 0.0062 | 0.0220 | 0.0772 | 0.1297 | 0.1020 | 0.1334 | 0.5249 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1024 | 846 | | 3435 | 10087 | 659.3 | 219.85 | 229.57 | 300.23 | 381 | 422 | 474 | 560 | 656 | 739 | 815 | 886 | 962 | 0.0675 | 681 | 1.178 | 50.36 | 19.72 | 1 | 0.0387 | 133 | 0.0016 | 33.09 | 6.859 | 0.2760 | 482935.0 | 384000000 | 323000000000 | 284000000000000 | 0.4698 | 0.1835 | 0.0010 | 0.0008 | 0.0010 | 0.0008 | 0.0190 | 0.0041 | 0.0543 | 0.0094 | 0.1514 | 0.0513 | 0.2114 | 0.0871 | 0.1162 | 0.0675 | 0.1257 | 0.1037 | 0.3200 | 0.6753 | 0.0000 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0027 | 0.0044 | 0.0321 | 0.0267 | 0.0715 | 0.0507 | 0.0357 | 0.0311 | 0.0632 | 0.0504 | 0.7948 | 0.8347 | 0.0009 | 0.0040 | 0.0009 | 0.0040 | 0.0053 | 0.0180 | 0.0132 | 0.0360 | 0.0618 | 0.0900 | 0.1103 | 0.1260 | 0.0688 | 0.1200 | 0.0980 | 0.1420 | 0.6408 | 0.4600 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0445 | 0.0890 | 0.0504 | 0.0878 | 0.7237 | 18 | 25 | 41 | 66 | 110 | 168 | 254 | 377 | 603 | 0.0320 | 31.34 | 5.547 | 0.4433 | 142832.0 | 138000000 | 168000000000 | 236000000000000 | 0.5550 | 0.1375 | 0.0682 | 0.0019 | 0.1896 | 0.0238 | 0.3009 | 0.1211 | 0.1665 | 0.1477 | 0.1254 | 0.1809 | 0.0832 | 0.1847 | 0.0401 | 0.1328 | 0.0191 | 0.1164 | 0.0070 | 0.0907 | 0.0003 | 0.0002 | 0.0011 | 0.0004 | 0.0087 | 0.0040 | 0.0184 | 0.0141 | 0.0784 | 0.0693 | 0.1286 | 0.1141 | 0.0920 | 0.0812 | 0.1286 | 0.1212 | 0.5440 | 0.5954 | 0.0007 | 0.0021 | 0.0029 | 0.0050 | 0.0103 | 0.0117 | 0.0271 | 0.0364 | 0.0934 | 0.0899 | 0.1497 | 0.1527 | 0.0984 | 0.0933 | 0.1297 | 0.1217 | 0.4879 | 0.4872 | 0.0015 | 0.0018 | 0.0095 | 0.0160 | 0.0812 | 0.1482 | 0.0935 | 0.1316 | 0.5166 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 804 | 192 | | 9922 | 14775 | 134.6 | 40.27 | 276.51 | 259.87 | 90 | 102 | 111 | 120 | 129 | 139 | 151 | 165 | 185 | 0.0923 | 1363 | 0.678 | 210.00 | 48.17 | 5 | 0.0555 | 551 | 0.0016 | 25.40 | 6.776 | 0.2333 | 19732.5 | 3150000 | 551000000 | 105000000000 | 0.4834 | 0.1711 | 0.0002 | 0.0002 | 0.0017 | 0.0006 | 0.0103 | 0.0011 | 0.0422 | 0.0040 | 0.1105 | 0.0312 | 0.1807 | 0.0675 | 0.1790 | 0.0732 | 0.1797 | 0.1114 | 0.2958 | 0.7108 | 0.0000 | 0.0001 | 0.0008 | 0.0005 | 0.0029 | 0.0007 | 0.0109 | 0.0020 | 0.0409 | 0.0198 | 0.0753 | 0.0371 | 0.0711 | 0.0313 | 0.0968 | 0.0504 | 0.7013 | 0.8580 | 0.0027 | 0.0123 | 0.0096 | 0.0212 | 0.0183 | 0.0368 | 0.0636 | 0.0982 | 0.1208 | 0.1618 | 0.1707 | 0.1696 | 0.1304 | 0.1027 | 0.1405 | 0.1395 | 0.3432 | 0.2578 | 0.0009 | 0.0023 | 0.0100 | 0.0275 | 0.0776 | 0.1327 | 0.1116 | 0.1316 | 0.5059 | 27 | 54 | 105 | 157 | 206 | 265 | 334 | 441 | 628 | 0.0057 | 57.11 | 6.881 | 0.3026 | 143987.0 | 105000000 | 93700000000 | 95000000000000 | 0.6013 | 0.0968 | 0.0216 | 0.0014 | 0.0960 | 0.0083 | 0.1877 | 0.0540 | 0.1629 | 0.0789 | 0.1693 | 0.1505 | 0.1733 | 0.1848 | 0.0968 | 0.1576 | 0.0464 | 0.1582 | 0.0460 | 0.2061 | 0.0006 | 0.0002 | 0.0016 | 0.0005 | 0.0059 | 0.0036 | 0.0231 | 0.0129 | 0.0764 | 0.0640 | 0.1265 | 0.1009 | 0.0993 | 0.0832 | 0.1089 | 0.1172 | 0.5577 | 0.6175 | 0.0025 | 0.0011 | 0.0056 | 0.0083 | 0.0181 | 0.0174 | 0.0350 | 0.0365 | 0.0934 | 0.0970 | 0.1313 | 0.1352 | 0.0834 | 0.0918 | 0.1084 | 0.1086 | 0.5223 | 0.5041 | 0.0012 | 0.0041 | 0.0118 | 0.0325 | 0.0905 | 0.1330 | 0.0907 | 0.1109 | 0.5253 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 462 | | 6757 | 10694 | 103.6 | 26.81 | 127.16 | 113.08 | 75 | 82 | 88 | 93 | 98 | 104 | 112 | 123 | 140 | 0.0902 | 965 | 1.167 | 103.82 | 31.40 | 1 | 0.0364 | 246 | 0.0039 | 11.91 | 5.964 | 0.3215 | 11459.3 | 1360000 | 172000000 | 23500000000 | 0.4214 | 0.2299 | 0.0010 | 0.0000 | 0.0030 | 0.0000 | 0.0088 | 0.0010 | 0.0340 | 0.0029 | 0.0862 | 0.0218 | 0.1582 | 0.0506 | 0.1512 | 0.0465 | 0.1907 | 0.0759 | 0.3668 | 0.8013 | 0.0006 | 0.0000 | 0.0013 | 0.0000 | 0.0044 | 0.0003 | 0.0169 | 0.0005 | 0.0417 | 0.0128 | 0.0730 | 0.0254 | 0.0763 | 0.0197 | 0.1012 | 0.0369 | 0.6846 | 0.9045 | 0.0039 | 0.0036 | 0.0093 | 0.0000 | 0.0171 | 0.0342 | 0.0497 | 0.0739 | 0.0994 | 0.1586 | 0.1654 | 0.2036 | 0.1165 | 0.1243 | 0.1405 | 0.1333 | 0.3983 | 0.2685 | 0.0040 | 0.0058 | 0.0112 | 0.0426 | 0.0834 | 0.1119 | 0.0888 | 0.1241 | 0.5283 | 17 | 32 | 49 | 71 | 97 | 124 | 158 | 204 | 276 | 0.0049 | 28.88 | 6.477 | 0.3379 | 28954.2 | 9110000 | 3510000000 | 1540000000000 | 0.5010 | 0.1908 | 0.0104 | 0.0014 | 0.0825 | 0.0080 | 0.1622 | 0.0280 | 0.1715 | 0.0704 | 0.1802 | 0.1431 | 0.1846 | 0.1949 | 0.0978 | 0.1574 | 0.0672 | 0.1528 | 0.0437 | 0.2441 | 0.0002 | 0.0005 | 0.0006 | 0.0006 | 0.0043 | 0.0027 | 0.0166 | 0.0116 | 0.0621 | 0.0488 | 0.1025 | 0.0778 | 0.0847 | 0.0716 | 0.1177 | 0.0936 | 0.6114 | 0.6925 | 0.0027 | 0.0022 | 0.0036 | 0.0056 | 0.0141 | 0.0086 | 0.0335 | 0.0365 | 0.0847 | 0.0941 | 0.1182 | 0.1391 | 0.0972 | 0.0926 | 0.1152 | 0.1183 | 0.5308 | 0.5030 | 0.0007 | 0.0021 | 0.0060 | 0.0293 | 0.0767 | 0.1199 | 0.0870 | 0.1146 | 0.5636 | ||
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 469 | 438 | | 2983 | 6904 | 291.5 | 155.73 | 25.80 | 36.51 | 163 | 179 | 192 | 210 | 232 | 259 | 292 | 423 | 579 | 0.1047 | 723 | 0.563 | 78.24 | 21.26 | 5 | 0.0865 | 258 | 0.0031 | 12.41 | 6.310 | 0.3653 | 109220.0 | 50500000 | 26800000000 | 15300000000000 | 0.4115 | 0.2245 | 0.0013 | 0.0000 | 0.0013 | 0.0011 | 0.0053 | 0.0049 | 0.0279 | 0.0152 | 0.0810 | 0.0455 | 0.1514 | 0.0829 | 0.1142 | 0.0650 | 0.1116 | 0.0861 | 0.5060 | 0.6994 | 0.0007 | 0.0000 | 0.0007 | 0.0008 | 0.0027 | 0.0036 | 0.0129 | 0.0101 | 0.0278 | 0.0283 | 0.0394 | 0.0449 | 0.0455 | 0.0377 | 0.0502 | 0.0494 | 0.8201 | 0.8251 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0048 | 0.0250 | 0.0353 | 0.0722 | 0.0609 | 0.0222 | 0.0304 | 0.0431 | 0.0529 | 0.8333 | 0.8157 | 0.0000 | 0.0022 | 0.0078 | 0.0100 | 0.0288 | 0.0654 | 0.0310 | 0.0488 | 0.8060 | 7 | 9 | 10 | 12 | 14 | 17 | 22 | 30 | 49 | 0.1051 | 1.66 | 3.110 | 0.7374 | 1998.1 | 320182 | 69200000 | 17600000000 | 0.5249 | 0.1326 | 0.0229 | 0.0158 | 0.0439 | 0.0273 | 0.0768 | 0.0379 | 0.1286 | 0.0532 | 0.1655 | 0.0873 | 0.1864 | 0.1237 | 0.1685 | 0.1324 | 0.1256 | 0.1938 | 0.0818 | 0.3285 | 0.0053 | 0.0100 | 0.0107 | 0.0158 | 0.0191 | 0.0197 | 0.0364 | 0.0262 | 0.0631 | 0.0494 | 0.1039 | 0.0862 | 0.0795 | 0.0733 | 0.0955 | 0.1172 | 0.5866 | 0.6021 | 0.0056 | 0.0129 | 0.0104 | 0.0069 | 0.0288 | 0.0247 | 0.0400 | 0.0366 | 0.0737 | 0.0791 | 0.1017 | 0.1098 | 0.0745 | 0.0692 | 0.1129 | 0.0930 | 0.5524 | 0.5678 | 0.0070 | 0.0152 | 0.0275 | 0.0427 | 0.0719 | 0.1029 | 0.0830 | 0.0918 | 0.5582 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 374 | 827 | | 538 | 5755 | 91.8 | 48.44 | 171.54 | 297.95 | 29 | 40 | 57 | 74 | 89 | 101 | 116 | 140 | 161 | 0.0895 | 515 | 1.275 | 31.62 | 12.17 | 2 | 0.1543 | 83 | 0.0025 | 70.15 | 6.080 | 0.1560 | 10772.9 | 1460000 | 216000000 | 34000000000 | 0.3272 | 0.2735 | 0.0000 | 0.0000 | 0.0282 | 0.0000 | 0.1338 | 0.0000 | 0.1901 | 0.0198 | 0.1620 | 0.1581 | 0.1268 | 0.1937 | 0.1479 | 0.1621 | 0.1056 | 0.1581 | 0.1056 | 0.3083 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0031 | 0.0131 | 0.0800 | 0.0551 | 0.0985 | 0.0866 | 0.0431 | 0.0525 | 0.1138 | 0.0840 | 0.6585 | 0.7087 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0055 | 0.0000 | 0.0383 | 0.0156 | 0.1038 | 0.1328 | 0.1038 | 0.1016 | 0.1093 | 0.1016 | 0.1421 | 0.1328 | 0.4973 | 0.5000 | 0.0000 | 0.0000 | 0.0078 | 0.0389 | 0.0661 | 0.1128 | 0.0973 | 0.1128 | 0.5642 | 17 | 19 | 20 | 22 | 25 | 35 | 92 | 249 | 645 | 0.1812 | 27.53 | 3.742 | 0.6466 | 118185.0 | 112000000 | 119000000000 | 139000000000000 | 0.7250 | 0.0477 | 0.0600 | 0.0080 | 0.2240 | 0.0282 | 0.3600 | 0.1690 | 0.1600 | 0.1932 | 0.0920 | 0.2012 | 0.0480 | 0.1469 | 0.0240 | 0.1066 | 0.0240 | 0.0624 | 0.0080 | 0.0845 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0020 | 0.0012 | 0.0231 | 0.0168 | 0.0909 | 0.0895 | 0.1324 | 0.1111 | 0.0856 | 0.0847 | 0.1232 | 0.1219 | 0.5422 | 0.5742 | 0.0000 | 0.0000 | 0.0047 | 0.0060 | 0.0087 | 0.0146 | 0.0379 | 0.0368 | 0.0883 | 0.0856 | 0.1270 | 0.1336 | 0.1017 | 0.0967 | 0.1222 | 0.1182 | 0.5095 | 0.5086 | 0.0000 | 0.0000 | 0.0086 | 0.0281 | 0.0944 | 0.1354 | 0.0929 | 0.1218 | 0.5187 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 343 | 118 | | 16901 | 26398 | 141.3 | 44.30 | 218.23 | 252.21 | 94 | 105 | 114 | 123 | 132 | 143 | 157 | 175 | 204 | 0.0815 | 2151 | 0.681 | 101.95 | 26.17 | 6 | 0.0180 | 304 | 0.0015 | 29.37 | 6.914 | 0.2233 | 21941.5 | 3740000 | 696000000 | 140000000000 | 0.5305 | 0.1501 | 0.0011 | 0.0003 | 0.0048 | 0.0008 | 0.0158 | 0.0020 | 0.0410 | 0.0075 | 0.1072 | 0.0328 | 0.1650 | 0.0728 | 0.1666 | 0.0720 | 0.1890 | 0.1025 | 0.3095 | 0.7093 | 0.0006 | 0.0002 | 0.0026 | 0.0004 | 0.0058 | 0.0011 | 0.0146 | 0.0036 | 0.0408 | 0.0175 | 0.0693 | 0.0366 | 0.0679 | 0.0300 | 0.0954 | 0.0486 | 0.7030 | 0.8620 | 0.0021 | 0.0030 | 0.0070 | 0.0090 | 0.0120 | 0.0200 | 0.0527 | 0.0656 | 0.1020 | 0.1512 | 0.1411 | 0.1773 | 0.1049 | 0.1097 | 0.1331 | 0.1607 | 0.4451 | 0.3035 | 0.0015 | 0.0049 | 0.0131 | 0.0289 | 0.0754 | 0.1125 | 0.0940 | 0.1202 | 0.5495 | 20 | 29 | 48 | 79 | 120 | 175 | 259 | 375 | 570 | 0.0118 | 66.19 | 6.470 | 0.3644 | 111232.0 | 85900000 | 88000000000 | 113000000000000 | 0.5942 | 0.0903 | 0.0589 | 0.0022 | 0.1898 | 0.0187 | 0.2385 | 0.1095 | 0.1625 | 0.1457 | 0.1298 | 0.1893 | 0.1051 | 0.1818 | 0.0549 | 0.1192 | 0.0407 | 0.1100 | 0.0196 | 0.1236 | 0.0006 | 0.0005 | 0.0022 | 0.0016 | 0.0043 | 0.0051 | 0.0185 | 0.0152 | 0.0708 | 0.0630 | 0.1147 | 0.0979 | 0.0818 | 0.0754 | 0.1208 | 0.1064 | 0.5863 | 0.6349 | 0.0003 | 0.0018 | 0.0031 | 0.0043 | 0.0077 | 0.0110 | 0.0323 | 0.0372 | 0.0907 | 0.0969 | 0.1399 | 0.1479 | 0.1021 | 0.1013 | 0.1285 | 0.1341 | 0.4956 | 0.4656 | 0.0010 | 0.0025 | 0.0059 | 0.0245 | 0.0763 | 0.1324 | 0.0895 | 0.1228 | 0.5449 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1047 | 808 | | 11793 | 29672 | 113.4 | 29.34 | 199.72 | 175.90 | 81 | 89 | 96 | 102 | 108 | 115 | 124 | 135 | 153 | 0.0534 | 1583 | 0.454 | 192.20 | 38.59 | 5 | 0.0484 | 571 | 0.0029 | 15.86 | 6.239 | 0.2893 | 13720.4 | 1780000 | 247000000 | 36900000000 | 0.5494 | 0.1414 | 0.0009 | 0.0000 | 0.0048 | 0.0002 | 0.0148 | 0.0015 | 0.0418 | 0.0067 | 0.0987 | 0.0255 | 0.1564 | 0.0610 | 0.1565 | 0.0585 | 0.1823 | 0.0902 | 0.3439 | 0.7563 | 0.0005 | 0.0000 | 0.0016 | 0.0002 | 0.0052 | 0.0007 | 0.0169 | 0.0038 | 0.0447 | 0.0139 | 0.0787 | 0.0369 | 0.0757 | 0.0239 | 0.1044 | 0.0426 | 0.6722 | 0.8779 | 0.0055 | 0.0043 | 0.0115 | 0.0182 | 0.0243 | 0.0503 | 0.0545 | 0.1146 | 0.1261 | 0.1767 | 0.1530 | 0.1734 | 0.1129 | 0.1199 | 0.1500 | 0.1370 | 0.3622 | 0.2056 | 0.0035 | 0.0069 | 0.0125 | 0.0420 | 0.0881 | 0.1219 | 0.1128 | 0.1261 | 0.4861 | 21 | 40 | 70 | 109 | 156 | 208 | 264 | 334 | 444 | 0.0045 | 62.50 | 7.035 | 0.2736 | 70826.1 | 33200000 | 18700000000 | 12000000000000 | 0.4909 | 0.1748 | 0.0241 | 0.0016 | 0.1156 | 0.0080 | 0.2373 | 0.0460 | 0.1905 | 0.1069 | 0.1697 | 0.1785 | 0.1335 | 0.2098 | 0.0719 | 0.1527 | 0.0399 | 0.1470 | 0.0174 | 0.1495 | 0.0004 | 0.0002 | 0.0009 | 0.0011 | 0.0042 | 0.0023 | 0.0126 | 0.0094 | 0.0581 | 0.0468 | 0.1027 | 0.0856 | 0.0862 | 0.0727 | 0.1139 | 0.0958 | 0.6211 | 0.6861 | 0.0010 | 0.0011 | 0.0048 | 0.0062 | 0.0108 | 0.0147 | 0.0306 | 0.0373 | 0.0810 | 0.0966 | 0.1391 | 0.1521 | 0.1107 | 0.1138 | 0.1321 | 0.1356 | 0.4899 | 0.4427 | 0.0002 | 0.0024 | 0.0061 | 0.0189 | 0.0699 | 0.1259 | 0.0994 | 0.1257 | 0.5515 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 481 | 100 | | 7950 | 9207 | 278.6 | 129.42 | 10.26 | 12.06 | 144 | 163 | 187 | 215 | 241 | 273 | 314 | 413 | 495 | 0.0924 | 851 | 0.695 | 94.53 | 15.03 | 6 | 0.0267 | 212 | 0.0018 | 9.35 | 6.724 | 0.3596 | 94338.5 | 37400000 | 16500000000 | 7810000000000 | 0.4212 | 0.2162 | 0.0009 | 0.0016 | 0.0013 | 0.0016 | 0.0068 | 0.0043 | 0.0175 | 0.0086 | 0.0554 | 0.0374 | 0.0967 | 0.0491 | 0.0797 | 0.0423 | 0.1121 | 0.0623 | 0.6297 | 0.7930 | 0.0004 | 0.0011 | 0.0007 | 0.0010 | 0.0027 | 0.0027 | 0.0064 | 0.0047 | 0.0202 | 0.0199 | 0.0282 | 0.0236 | 0.0285 | 0.0216 | 0.0407 | 0.0308 | 0.8721 | 0.8946 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0028 | 0.0017 | 0.0070 | 0.0091 | 0.0167 | 0.0205 | 0.0423 | 0.0400 | 0.0265 | 0.0377 | 0.0307 | 0.0354 | 0.8721 | 0.8556 | 0.0010 | 0.0016 | 0.0049 | 0.0092 | 0.0191 | 0.0384 | 0.0309 | 0.0427 | 0.8521 | 3 | 5 | 5 | 6 | 7 | 8 | 9 | 11 | 19 | 0.1322 | 0.45 | 1.509 | 0.5124 | 250.6 | 12213 | 813301 | 62700000 | 0.5153 | 0.1526 | 0.0886 | 0.0079 | 0.2162 | 0.0407 | 0.2503 | 0.0797 | 0.2088 | 0.1421 | 0.1362 | 0.1824 | 0.0696 | 0.1959 | 0.0225 | 0.1743 | 0.0078 | 0.1275 | 0.0000 | 0.0493 | 0.0425 | 0.0045 | 0.1012 | 0.0274 | 0.1320 | 0.0540 | 0.1129 | 0.0995 | 0.0975 | 0.1431 | 0.0935 | 0.1554 | 0.0649 | 0.1304 | 0.0728 | 0.1196 | 0.2827 | 0.2662 | 0.0790 | 0.0376 | 0.0515 | 0.0295 | 0.0334 | 0.0302 | 0.0322 | 0.0376 | 0.0632 | 0.0604 | 0.0971 | 0.1150 | 0.0872 | 0.0825 | 0.0989 | 0.1098 | 0.4576 | 0.4974 | 0.1005 | 0.0895 | 0.0781 | 0.0561 | 0.0570 | 0.0875 | 0.0557 | 0.0858 | 0.3897 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 219 | 745 | | 5417 | 7682 | 459.9 | 105.22 | 163.49 | 154.87 | 337 | 370 | 397 | 421 | 446 | 473 | 502 | 541 | 606 | 0.1009 | 775 | 0.952 | 103.82 | 28.00 | 1 | 0.0462 | 250 | 0.0007 | 65.25 | 7.472 | 0.1512 | 222541.0 | 113000000 | 60600000000 | 34000000000000 | 0.4352 | 0.2219 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0012 | 0.0002 | 0.0160 | 0.0018 | 0.0690 | 0.0207 | 0.1406 | 0.0417 | 0.1432 | 0.0435 | 0.1788 | 0.0688 | 0.4498 | 0.8231 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0073 | 0.0006 | 0.0381 | 0.0131 | 0.0709 | 0.0252 | 0.0628 | 0.0204 | 0.0986 | 0.0385 | 0.7212 | 0.9023 | 0.0061 | 0.0059 | 0.0163 | 0.0088 | 0.0132 | 0.0147 | 0.0499 | 0.1003 | 0.0957 | 0.1504 | 0.1232 | 0.1681 | 0.0896 | 0.1386 | 0.0998 | 0.1534 | 0.5061 | 0.2596 | 0.0016 | 0.0041 | 0.0086 | 0.0345 | 0.0858 | 0.1248 | 0.0998 | 0.1281 | 0.5127 | 16 | 24 | 47 | 80 | 120 | 162 | 209 | 275 | 401 | 0.0119 | 39.04 | 6.336 | 0.3337 | 50710.0 | 20800000 | 10000000000 | 5380000000000 | 0.5608 | 0.1109 | 0.0360 | 0.0009 | 0.1274 | 0.0147 | 0.1801 | 0.0477 | 0.1670 | 0.1198 | 0.1511 | 0.1590 | 0.1292 | 0.1862 | 0.1002 | 0.1203 | 0.0712 | 0.1323 | 0.0378 | 0.2192 | 0.0008 | 0.0002 | 0.0011 | 0.0005 | 0.0016 | 0.0021 | 0.0153 | 0.0143 | 0.0629 | 0.0509 | 0.1018 | 0.0835 | 0.0862 | 0.0685 | 0.1314 | 0.1042 | 0.5988 | 0.6757 | 0.0020 | 0.0020 | 0.0016 | 0.0045 | 0.0115 | 0.0109 | 0.0262 | 0.0377 | 0.0994 | 0.0942 | 0.1224 | 0.1413 | 0.0970 | 0.0932 | 0.1431 | 0.1413 | 0.4968 | 0.4750 | 0.0000 | 0.0010 | 0.0056 | 0.0203 | 0.0811 | 0.1353 | 0.0889 | 0.1366 | 0.5312 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 158 | 814 | | 6792 | 9233 | 438.4 | 87.62 | 129.25 | 126.89 | 328 | 360 | 387 | 410 | 432 | 453 | 478 | 510 | 563 | 0.1039 | 959 | 1.120 | 105.12 | 29.02 | 1 | 0.0346 | 235 | 0.0009 | 45.63 | 7.284 | 0.1766 | 199847.0 | 94600000 | 46500000000 | 23600000000000 | 0.4114 | 0.2340 | 0.0002 | 0.0000 | 0.0009 | 0.0002 | 0.0029 | 0.0003 | 0.0152 | 0.0014 | 0.0530 | 0.0166 | 0.1082 | 0.0302 | 0.1148 | 0.0269 | 0.1594 | 0.0440 | 0.5454 | 0.8804 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0064 | 0.0000 | 0.0246 | 0.0109 | 0.0515 | 0.0199 | 0.0494 | 0.0108 | 0.0729 | 0.0223 | 0.7933 | 0.9361 | 0.0091 | 0.0087 | 0.0172 | 0.0435 | 0.0199 | 0.0913 | 0.0661 | 0.1174 | 0.1024 | 0.2261 | 0.1386 | 0.1174 | 0.1232 | 0.1739 | 0.1132 | 0.0870 | 0.4103 | 0.1348 | 0.0006 | 0.0025 | 0.0094 | 0.0253 | 0.0738 | 0.1200 | 0.1088 | 0.1385 | 0.5211 | 15 | 21 | 36 | 60 | 91 | 123 | 163 | 221 | 310 | 0.0144 | 22.41 | 5.893 | 0.4120 | 32805.8 | 11500000 | 4920000000 | 2420000000000 | 0.5918 | 0.1102 | 0.0326 | 0.0008 | 0.0932 | 0.0126 | 0.1546 | 0.0502 | 0.1430 | 0.0942 | 0.1492 | 0.1468 | 0.1430 | 0.1554 | 0.1072 | 0.1181 | 0.1049 | 0.1370 | 0.0723 | 0.2849 | 0.0002 | 0.0000 | 0.0012 | 0.0004 | 0.0062 | 0.0042 | 0.0208 | 0.0156 | 0.0649 | 0.0540 | 0.0900 | 0.0828 | 0.0815 | 0.0608 | 0.1083 | 0.0905 | 0.6269 | 0.6917 | 0.0017 | 0.0008 | 0.0031 | 0.0078 | 0.0133 | 0.0090 | 0.0269 | 0.0377 | 0.0941 | 0.1099 | 0.1339 | 0.1333 | 0.0896 | 0.1005 | 0.1210 | 0.1255 | 0.5164 | 0.4754 | 0.0009 | 0.0028 | 0.0079 | 0.0247 | 0.0791 | 0.1123 | 0.0879 | 0.1140 | 0.5705 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 600 | | 4616 | 7928 | 344.2 | 66.06 | 265.90 | 254.61 | 259 | 286 | 308 | 325 | 341 | 359 | 377 | 401 | 435 | 0.1043 | 827 | 1.180 | 138.18 | 54.34 | 1 | 0.0782 | 361 | 0.0012 | 25.73 | 6.964 | 0.2269 | 122856.0 | 45400000 | 17300000000 | 6770000000000 | 0.4140 | 0.2347 | 0.0009 | 0.0000 | 0.0025 | 0.0002 | 0.0041 | 0.0002 | 0.0173 | 0.0013 | 0.0447 | 0.0183 | 0.0676 | 0.0359 | 0.0711 | 0.0219 | 0.1101 | 0.0415 | 0.6818 | 0.8807 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0007 | 0.0197 | 0.0159 | 0.0277 | 0.0303 | 0.0289 | 0.0135 | 0.0451 | 0.0266 | 0.8668 | 0.9131 | 0.0028 | 0.0000 | 0.0041 | 0.0000 | 0.0180 | 0.0000 | 0.0511 | 0.0000 | 0.0898 | 0.0000 | 0.1367 | 0.0000 | 0.1450 | 0.0000 | 0.1257 | 0.0000 | 0.4268 | 0.0000 | 0.0013 | 0.0031 | 0.0071 | 0.0205 | 0.0361 | 0.0672 | 0.0828 | 0.1033 | 0.6785 | 30 | 47 | 84 | 143 | 199 | 254 | 331 | 426 | 605 | 0.0066 | 47.91 | 6.596 | 0.3097 | 135523.0 | 96800000 | 84600000000 | 83800000000000 | 0.5314 | 0.1336 | 0.0148 | 0.0008 | 0.0818 | 0.0076 | 0.2167 | 0.0239 | 0.1528 | 0.0725 | 0.1730 | 0.1457 | 0.1302 | 0.1803 | 0.1005 | 0.1489 | 0.0733 | 0.1636 | 0.0569 | 0.2568 | 0.0000 | 0.0000 | 0.0011 | 0.0007 | 0.0061 | 0.0013 | 0.0143 | 0.0088 | 0.0586 | 0.0424 | 0.1040 | 0.0805 | 0.0828 | 0.0621 | 0.1157 | 0.0988 | 0.6175 | 0.7053 | 0.0008 | 0.0010 | 0.0016 | 0.0075 | 0.0076 | 0.0139 | 0.0298 | 0.0378 | 0.0953 | 0.0925 | 0.1460 | 0.1492 | 0.0973 | 0.1089 | 0.1375 | 0.1318 | 0.4841 | 0.4575 | 0.0003 | 0.0016 | 0.0046 | 0.0178 | 0.0753 | 0.1358 | 0.0976 | 0.1289 | 0.5381 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1098 | 160 | | 13724 | 21102 | 109.6 | 32.03 | 139.67 | 113.32 | 75 | 84 | 91 | 97 | 104 | 112 | 121 | 133 | 152 | 0.0598 | 1262 | 0.543 | 155.77 | 38.28 | 1 | 0.0358 | 491 | 0.0012 | 36.99 | 7.099 | 0.2067 | 13040.5 | 1690000 | 237000000 | 36400000000 | 0.4757 | 0.1867 | 0.0010 | 0.0001 | 0.0041 | 0.0003 | 0.0130 | 0.0016 | 0.0426 | 0.0043 | 0.0995 | 0.0236 | 0.1665 | 0.0560 | 0.1630 | 0.0574 | 0.1878 | 0.0954 | 0.3226 | 0.7614 | 0.0005 | 0.0001 | 0.0013 | 0.0001 | 0.0034 | 0.0002 | 0.0125 | 0.0008 | 0.0402 | 0.0130 | 0.0734 | 0.0252 | 0.0716 | 0.0218 | 0.1009 | 0.0456 | 0.6963 | 0.8934 | 0.0044 | 0.0054 | 0.0078 | 0.0168 | 0.0271 | 0.0337 | 0.0640 | 0.0804 | 0.1118 | 0.1692 | 0.1406 | 0.1937 | 0.1349 | 0.1026 | 0.1386 | 0.1394 | 0.3707 | 0.2588 | 0.0024 | 0.0058 | 0.0129 | 0.0351 | 0.0814 | 0.1154 | 0.0950 | 0.1140 | 0.5380 | 25 | 40 | 60 | 83 | 110 | 142 | 177 | 222 | 298 | 0.0094 | 10.78 | 5.597 | 0.4544 | 32349.4 | 10000000 | 3730000000 | 1590000000000 | 0.5105 | 0.1695 | 0.0131 | 0.0019 | 0.0728 | 0.0040 | 0.1644 | 0.0224 | 0.1683 | 0.0713 | 0.1736 | 0.1476 | 0.1439 | 0.1890 | 0.1111 | 0.1477 | 0.0831 | 0.1506 | 0.0697 | 0.2653 | 0.0009 | 0.0007 | 0.0013 | 0.0014 | 0.0035 | 0.0034 | 0.0133 | 0.0126 | 0.0502 | 0.0386 | 0.0839 | 0.0657 | 0.0680 | 0.0578 | 0.1044 | 0.0854 | 0.6745 | 0.7344 | 0.0012 | 0.0013 | 0.0045 | 0.0041 | 0.0086 | 0.0141 | 0.0281 | 0.0380 | 0.0821 | 0.1031 | 0.1290 | 0.1509 | 0.1030 | 0.1107 | 0.1319 | 0.1375 | 0.5116 | 0.4403 | 0.0013 | 0.0019 | 0.0052 | 0.0196 | 0.0680 | 0.1022 | 0.0904 | 0.1250 | 0.5864 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 935 | 650 | | 4467 | 9610 | 94.8 | 24.92 | 207.00 | 159.98 | 69 | 75 | 80 | 84 | 89 | 95 | 102 | 111 | 128 | 0.0728 | 700 | 0.935 | 58.80 | 21.38 | 2 | 0.0374 | 167 | 0.0023 | 22.65 | 6.438 | 0.2515 | 9610.2 | 1050000 | 124000000 | 15700000000 | 0.4444 | 0.2134 | 0.0007 | 0.0000 | 0.0055 | 0.0010 | 0.0092 | 0.0005 | 0.0283 | 0.0039 | 0.0881 | 0.0217 | 0.1418 | 0.0440 | 0.1686 | 0.0426 | 0.1851 | 0.0733 | 0.3728 | 0.8130 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0048 | 0.0000 | 0.0127 | 0.0016 | 0.0469 | 0.0122 | 0.0720 | 0.0228 | 0.0813 | 0.0176 | 0.1042 | 0.0375 | 0.6764 | 0.9083 | 0.0098 | 0.0137 | 0.0147 | 0.0000 | 0.0244 | 0.0192 | 0.0452 | 0.0658 | 0.1345 | 0.1699 | 0.1516 | 0.2000 | 0.1186 | 0.1151 | 0.1528 | 0.1699 | 0.3484 | 0.2466 | 0.0039 | 0.0055 | 0.0171 | 0.0473 | 0.0892 | 0.1244 | 0.1007 | 0.1172 | 0.4948 | 54 | 84 | 111 | 137 | 168 | 203 | 242 | 303 | 400 | 0.0032 | 28.25 | 6.373 | 0.3196 | 68440.7 | 32700000 | 20600000000 | 15800000000000 | 0.5401 | 0.1476 | 0.0155 | 0.0007 | 0.0447 | 0.0007 | 0.1182 | 0.0190 | 0.1771 | 0.0542 | 0.2087 | 0.1259 | 0.1908 | 0.1667 | 0.1258 | 0.1621 | 0.0810 | 0.1828 | 0.0382 | 0.2878 | 0.0008 | 0.0002 | 0.0010 | 0.0003 | 0.0045 | 0.0026 | 0.0207 | 0.0082 | 0.0649 | 0.0465 | 0.1107 | 0.0798 | 0.0944 | 0.0796 | 0.1265 | 0.1118 | 0.5765 | 0.6712 | 0.0018 | 0.0019 | 0.0080 | 0.0062 | 0.0123 | 0.0162 | 0.0355 | 0.0380 | 0.0952 | 0.1102 | 0.1509 | 0.1501 | 0.0955 | 0.1083 | 0.1404 | 0.1406 | 0.4604 | 0.4285 | 0.0005 | 0.0013 | 0.0099 | 0.0259 | 0.0863 | 0.1255 | 0.0978 | 0.1408 | 0.5120 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 402 | 281 | | 5163 | 11094 | 132.9 | 31.75 | 204.40 | 192.72 | 98 | 107 | 114 | 120 | 127 | 135 | 144 | 156 | 174 | 0.0753 | 835 | 1.001 | 90.14 | 24.74 | 1 | 0.0424 | 219 | 0.0024 | 20.29 | 6.351 | 0.2592 | 18683.1 | 2790000 | 443000000 | 75300000000 | 0.4578 | 0.1909 | 0.0003 | 0.0000 | 0.0025 | 0.0000 | 0.0034 | 0.0002 | 0.0224 | 0.0012 | 0.0771 | 0.0208 | 0.1572 | 0.0445 | 0.1683 | 0.0420 | 0.1981 | 0.0794 | 0.3707 | 0.8120 | 0.0002 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0091 | 0.0000 | 0.0343 | 0.0121 | 0.0698 | 0.0263 | 0.0770 | 0.0152 | 0.1062 | 0.0349 | 0.6996 | 0.9115 | 0.0044 | 0.0126 | 0.0142 | 0.0158 | 0.0230 | 0.0536 | 0.0678 | 0.1073 | 0.1497 | 0.1956 | 0.1913 | 0.1546 | 0.1049 | 0.1577 | 0.1355 | 0.1325 | 0.3093 | 0.1703 | 0.0031 | 0.0040 | 0.0108 | 0.0333 | 0.0787 | 0.1393 | 0.1016 | 0.1326 | 0.4966 | 20 | 34 | 61 | 100 | 147 | 198 | 262 | 353 | 492 | 0.0054 | 71.93 | 6.900 | 0.2998 | 78916.5 | 40300000 | 24100000000 | 16000000000000 | 0.4531 | 0.1995 | 0.0210 | 0.0003 | 0.1004 | 0.0108 | 0.2033 | 0.0378 | 0.1881 | 0.0917 | 0.1512 | 0.1677 | 0.1595 | 0.2108 | 0.0921 | 0.1540 | 0.0508 | 0.1423 | 0.0337 | 0.1847 | 0.0004 | 0.0002 | 0.0012 | 0.0020 | 0.0031 | 0.0030 | 0.0172 | 0.0109 | 0.0545 | 0.0442 | 0.0980 | 0.0771 | 0.0764 | 0.0584 | 0.1021 | 0.0867 | 0.6471 | 0.7176 | 0.0011 | 0.0020 | 0.0011 | 0.0023 | 0.0078 | 0.0106 | 0.0300 | 0.0381 | 0.0728 | 0.0866 | 0.1296 | 0.1333 | 0.0923 | 0.0899 | 0.1143 | 0.1148 | 0.5510 | 0.5224 | 0.0007 | 0.0014 | 0.0067 | 0.0219 | 0.0631 | 0.1112 | 0.0841 | 0.1170 | 0.5940 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1109 | 791 | | 9893 | 20116 | 97.3 | 34.99 | 152.25 | 139.00 | 59 | 71 | 78 | 85 | 92 | 100 | 109 | 122 | 142 | 0.0680 | 1367 | 0.691 | 64.66 | 21.00 | 2 | 0.0208 | 206 | 0.0011 | 48.57 | 7.180 | 0.2021 | 10687.4 | 1320000 | 184000000 | 28700000000 | 0.5283 | 0.1408 | 0.0017 | 0.0000 | 0.0030 | 0.0003 | 0.0286 | 0.0013 | 0.0650 | 0.0096 | 0.1374 | 0.0448 | 0.1825 | 0.0976 | 0.1668 | 0.0904 | 0.1696 | 0.1321 | 0.2454 | 0.6238 | 0.0009 | 0.0000 | 0.0010 | 0.0001 | 0.0048 | 0.0001 | 0.0158 | 0.0049 | 0.0504 | 0.0240 | 0.0807 | 0.0492 | 0.0728 | 0.0375 | 0.1094 | 0.0633 | 0.6642 | 0.8209 | 0.0008 | 0.0032 | 0.0055 | 0.0144 | 0.0152 | 0.0335 | 0.0601 | 0.0813 | 0.1261 | 0.1491 | 0.1582 | 0.1914 | 0.1290 | 0.1148 | 0.1472 | 0.1260 | 0.3579 | 0.2863 | 0.0016 | 0.0025 | 0.0094 | 0.0338 | 0.0912 | 0.1218 | 0.1065 | 0.1342 | 0.4990 | 16 | 34 | 57 | 83 | 111 | 147 | 192 | 251 | 344 | 0.0118 | 24.15 | 5.952 | 0.3916 | 42501.1 | 16300000 | 7740000000 | 4260000000000 | 0.4988 | 0.1607 | 0.0275 | 0.0011 | 0.1169 | 0.0097 | 0.2130 | 0.0538 | 0.1636 | 0.0856 | 0.1683 | 0.1643 | 0.1424 | 0.1882 | 0.0820 | 0.1427 | 0.0568 | 0.1438 | 0.0296 | 0.2107 | 0.0004 | 0.0003 | 0.0017 | 0.0007 | 0.0039 | 0.0041 | 0.0160 | 0.0085 | 0.0595 | 0.0462 | 0.1060 | 0.0850 | 0.0867 | 0.0678 | 0.1130 | 0.1003 | 0.6127 | 0.6871 | 0.0008 | 0.0017 | 0.0031 | 0.0057 | 0.0093 | 0.0109 | 0.0287 | 0.0382 | 0.0867 | 0.1002 | 0.1526 | 0.1644 | 0.1028 | 0.1095 | 0.1329 | 0.1367 | 0.4830 | 0.4326 | 0.0001 | 0.0023 | 0.0070 | 0.0206 | 0.0702 | 0.1325 | 0.0932 | 0.1236 | 0.5506 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 177 | 313 | | 5638 | 13933 | 398.6 | 102.35 | 102.66 | 164.28 | 278 | 312 | 338 | 363 | 391 | 418 | 444 | 477 | 530 | 0.0646 | 900 | 1.105 | 128.16 | 40.36 | 1 | 0.0566 | 319 | 0.0011 | 32.90 | 7.036 | 0.2099 | 169382.0 | 76400000 | 36500000000 | 18500000000000 | 0.3917 | 0.2443 | 0.0000 | 0.0002 | 0.0018 | 0.0000 | 0.0052 | 0.0006 | 0.0231 | 0.0041 | 0.0686 | 0.0246 | 0.1196 | 0.0553 | 0.1310 | 0.0452 | 0.1734 | 0.0712 | 0.4774 | 0.7988 | 0.0000 | 0.0002 | 0.0007 | 0.0000 | 0.0025 | 0.0004 | 0.0080 | 0.0026 | 0.0243 | 0.0159 | 0.0491 | 0.0316 | 0.0505 | 0.0232 | 0.0757 | 0.0338 | 0.7892 | 0.8923 | 0.0054 | 0.0078 | 0.0045 | 0.0207 | 0.0118 | 0.0181 | 0.0570 | 0.0622 | 0.1230 | 0.1425 | 0.1203 | 0.2409 | 0.1401 | 0.1295 | 0.1528 | 0.1529 | 0.3852 | 0.2254 | 0.0011 | 0.0011 | 0.0023 | 0.0196 | 0.0495 | 0.1072 | 0.0966 | 0.1076 | 0.6149 | 10 | 13 | 19 | 31 | 50 | 75 | 104 | 145 | 221 | 0.0586 | 9.85 | 4.528 | 0.5850 | 37525.9 | 28000000 | 28100000000 | 32100000000000 | 0.6066 | 0.1047 | 0.0130 | 0.0014 | 0.0691 | 0.0060 | 0.1943 | 0.0246 | 0.2038 | 0.0773 | 0.1991 | 0.1586 | 0.1471 | 0.2025 | 0.0939 | 0.1627 | 0.0585 | 0.1518 | 0.0213 | 0.2151 | 0.0004 | 0.0002 | 0.0023 | 0.0006 | 0.0041 | 0.0022 | 0.0209 | 0.0180 | 0.0638 | 0.0512 | 0.0976 | 0.0888 | 0.0749 | 0.0667 | 0.1049 | 0.0915 | 0.6311 | 0.6808 | 0.0012 | 0.0036 | 0.0023 | 0.0047 | 0.0092 | 0.0118 | 0.0286 | 0.0383 | 0.0754 | 0.0777 | 0.1265 | 0.1310 | 0.0826 | 0.0917 | 0.1129 | 0.1167 | 0.5614 | 0.5245 | 0.0014 | 0.0033 | 0.0064 | 0.0226 | 0.0683 | 0.1045 | 0.0824 | 0.1106 | 0.6005 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1163 | 489 | | 321 | 5383 | 116.6 | 17.58 | 10.59 | 16.86 | 93 | 99 | 105 | 110 | 115 | 122 | 128 | 133 | 140 | 0.0832 | 448 | 1.174 | 34.48 | 13.89 | 3 | 0.2897 | 93 | 0.0412 | 1.34 | 3.375 | 0.6192 | 13896.5 | 1690000 | 210000000 | 26600000000 | 0.3932 | 0.2232 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0388 | 0.0156 | 0.0930 | 0.0498 | 0.1395 | 0.1090 | 0.1395 | 0.0592 | 0.1938 | 0.0935 | 0.3837 | 0.6729 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0243 | 0.0156 | 0.0590 | 0.0498 | 0.1007 | 0.1090 | 0.0833 | 0.0592 | 0.1111 | 0.0935 | 0.6146 | 0.6729 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.1000 | 0.0000 | 0.1000 | 0.0000 | 0.0333 | 0.0000 | 0.0000 | 0.0000 | 0.0258 | 0.0516 | 0.0839 | 0.1290 | 0.0710 | 0.1032 | 0.5355 | 3 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 13 | 0.1037 | 0.50 | 1.327 | 0.4010 | 396.2 | 39837.1 | 5690000 | 976000000 | 0.5867 | 0.1158 | 0.1081 | 0.0234 | 0.1521 | 0.0646 | 0.1822 | 0.1055 | 0.1683 | 0.1248 | 0.1992 | 0.1564 | 0.1228 | 0.1745 | 0.0533 | 0.1681 | 0.0139 | 0.1293 | 0.0000 | 0.0533 | 0.0717 | 0.0199 | 0.1019 | 0.0545 | 0.1150 | 0.0857 | 0.0980 | 0.0980 | 0.1194 | 0.1193 | 0.1073 | 0.1330 | 0.0772 | 0.1375 | 0.0728 | 0.1248 | 0.2366 | 0.2273 | 0.0433 | 0.0158 | 0.0226 | 0.0204 | 0.0377 | 0.0226 | 0.0377 | 0.0385 | 0.0734 | 0.0973 | 0.1092 | 0.1154 | 0.0923 | 0.0905 | 0.1224 | 0.1222 | 0.4614 | 0.4774 | 0.1188 | 0.1103 | 0.0827 | 0.0562 | 0.0615 | 0.0679 | 0.0679 | 0.0933 | 0.3415 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 835 | 674 | | 1286 | 9006 | 107.9 | 35.92 | 236.20 | 179.35 | 71 | 83 | 90 | 96 | 102 | 108 | 115 | 126 | 148 | 0.0815 | 734 | 0.834 | 60.64 | 18.97 | 2 | 0.1260 | 162 | 0.0037 | 21.25 | 5.914 | 0.2852 | 12925.5 | 1750000 | 272000000 | 48100000000 | 0.4873 | 0.1534 | 0.0027 | 0.0000 | 0.0054 | 0.0036 | 0.0308 | 0.0055 | 0.0496 | 0.0173 | 0.1300 | 0.0656 | 0.1662 | 0.0911 | 0.1421 | 0.0647 | 0.1568 | 0.1047 | 0.3164 | 0.6475 | 0.0000 | 0.0000 | 0.0031 | 0.0016 | 0.0134 | 0.0033 | 0.0237 | 0.0124 | 0.0792 | 0.0437 | 0.1132 | 0.0766 | 0.0792 | 0.0445 | 0.1091 | 0.0807 | 0.5792 | 0.7372 | 0.0088 | 0.0086 | 0.0088 | 0.0172 | 0.0265 | 0.0172 | 0.0929 | 0.0862 | 0.1106 | 0.1034 | 0.1593 | 0.1724 | 0.0885 | 0.0690 | 0.1283 | 0.1379 | 0.3761 | 0.3879 | 0.0038 | 0.0095 | 0.0302 | 0.0624 | 0.1078 | 0.1229 | 0.1096 | 0.1153 | 0.4386 | 21 | 54 | 101 | 156 | 212 | 269 | 324 | 398 | 492 | 0.0054 | 44.25 | 6.916 | 0.2857 | 87951.8 | 39600000 | 20100000000 | 11200000000000 | 0.5258 | 0.1424 | 0.0084 | 0.0013 | 0.0560 | 0.0023 | 0.1925 | 0.0179 | 0.2183 | 0.0737 | 0.2022 | 0.1661 | 0.1481 | 0.2268 | 0.0959 | 0.1657 | 0.0541 | 0.1561 | 0.0245 | 0.1900 | 0.0002 | 0.0002 | 0.0010 | 0.0009 | 0.0047 | 0.0025 | 0.0137 | 0.0101 | 0.0490 | 0.0402 | 0.0890 | 0.0809 | 0.0733 | 0.0592 | 0.1002 | 0.0870 | 0.6689 | 0.7190 | 0.0012 | 0.0019 | 0.0030 | 0.0054 | 0.0075 | 0.0103 | 0.0251 | 0.0387 | 0.0681 | 0.0831 | 0.1282 | 0.1543 | 0.1091 | 0.1091 | 0.1372 | 0.1313 | 0.5206 | 0.4659 | 0.0007 | 0.0036 | 0.0053 | 0.0177 | 0.0540 | 0.1087 | 0.0856 | 0.1201 | 0.6042 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 880 | 168 | | 38955 | 26240 | 163.7 | 54.42 | 189.84 | 155.38 | 92 | 114 | 132 | 148 | 164 | 179 | 194 | 210 | 233 | 0.1215 | 3188 | 0.799 | 74.95 | 17.03 | 13 | 0.0043 | 168 | 0.0008 | 32.80 | 7.366 | 0.2060 | 29769.9 | 5880000 | 1240000000 | 280000000000 | 0.5763 | 0.1150 | 0.0010 | 0.0002 | 0.0035 | 0.0005 | 0.0154 | 0.0020 | 0.0472 | 0.0094 | 0.1113 | 0.0378 | 0.1741 | 0.0717 | 0.1653 | 0.0787 | 0.1782 | 0.1069 | 0.3041 | 0.6929 | 0.0003 | 0.0001 | 0.0009 | 0.0002 | 0.0030 | 0.0009 | 0.0108 | 0.0048 | 0.0303 | 0.0203 | 0.0519 | 0.0341 | 0.0512 | 0.0327 | 0.0704 | 0.0446 | 0.7812 | 0.8624 | 0.0018 | 0.0076 | 0.0072 | 0.0135 | 0.0124 | 0.0327 | 0.0413 | 0.0819 | 0.0859 | 0.1325 | 0.1267 | 0.1726 | 0.1108 | 0.1197 | 0.1380 | 0.1307 | 0.4759 | 0.3088 | 0.0012 | 0.0016 | 0.0058 | 0.0209 | 0.0477 | 0.0807 | 0.0801 | 0.1009 | 0.6610 | 30 | 51 | 77 | 110 | 148 | 191 | 245 | 316 | 419 | 0.0043 | 23.31 | 6.446 | 0.3390 | 60178.8 | 24700000 | 11900000000 | 6310000000000 | 0.6103 | 0.0987 | 0.0154 | 0.0035 | 0.0720 | 0.0118 | 0.1491 | 0.0312 | 0.1825 | 0.0787 | 0.1846 | 0.1419 | 0.1799 | 0.1989 | 0.0982 | 0.1547 | 0.0673 | 0.1582 | 0.0509 | 0.2210 | 0.0009 | 0.0008 | 0.0043 | 0.0023 | 0.0067 | 0.0044 | 0.0211 | 0.0165 | 0.0660 | 0.0589 | 0.1135 | 0.1002 | 0.0823 | 0.0792 | 0.1052 | 0.1029 | 0.6000 | 0.6347 | 0.0009 | 0.0028 | 0.0066 | 0.0068 | 0.0095 | 0.0154 | 0.0324 | 0.0388 | 0.0825 | 0.0887 | 0.1348 | 0.1364 | 0.0914 | 0.0993 | 0.1153 | 0.1173 | 0.5266 | 0.4944 | 0.0018 | 0.0040 | 0.0100 | 0.0258 | 0.0759 | 0.1202 | 0.0937 | 0.1112 | 0.5575 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 659 | 864 | | 9157 | 12600 | 572.9 | 114.09 | 133.84 | 114.82 | 435 | 475 | 505 | 534 | 563 | 594 | 628 | 666 | 723 | 0.0900 | 1134 | 1.199 | 96.51 | 40.61 | 1 | 0.0284 | 260 | 0.0005 | 84.01 | 7.780 | 0.1396 | 341248.0 | 211000000 | 136000000000 | 90100000000000 | 0.4173 | 0.2328 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0001 | 0.0084 | 0.0014 | 0.0529 | 0.0133 | 0.1231 | 0.0303 | 0.1329 | 0.0280 | 0.1634 | 0.0394 | 0.5172 | 0.8876 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0045 | 0.0001 | 0.0267 | 0.0098 | 0.0603 | 0.0210 | 0.0668 | 0.0155 | 0.0864 | 0.0211 | 0.7545 | 0.9324 | 0.0022 | 0.0060 | 0.0129 | 0.0121 | 0.0237 | 0.0423 | 0.0760 | 0.0755 | 0.1097 | 0.1631 | 0.1627 | 0.1450 | 0.0968 | 0.1329 | 0.1168 | 0.1541 | 0.3993 | 0.2689 | 0.0000 | 0.0012 | 0.0046 | 0.0244 | 0.0835 | 0.1249 | 0.1047 | 0.1165 | 0.5403 | 14 | 26 | 50 | 78 | 106 | 138 | 176 | 224 | 297 | 0.0077 | 28.76 | 6.275 | 0.3483 | 31096.2 | 9370000 | 3320000000 | 1310000000000 | 0.6019 | 0.1025 | 0.0320 | 0.0017 | 0.1338 | 0.0087 | 0.2500 | 0.0546 | 0.1658 | 0.1008 | 0.1684 | 0.1801 | 0.1271 | 0.1957 | 0.0646 | 0.1465 | 0.0413 | 0.1349 | 0.0170 | 0.1769 | 0.0005 | 0.0004 | 0.0008 | 0.0005 | 0.0031 | 0.0019 | 0.0161 | 0.0096 | 0.0663 | 0.0503 | 0.1259 | 0.0945 | 0.0830 | 0.0727 | 0.1216 | 0.1056 | 0.5828 | 0.6645 | 0.0009 | 0.0012 | 0.0042 | 0.0084 | 0.0093 | 0.0160 | 0.0313 | 0.0389 | 0.1011 | 0.1062 | 0.1497 | 0.1596 | 0.1025 | 0.1120 | 0.1383 | 0.1416 | 0.4626 | 0.4161 | 0.0008 | 0.0029 | 0.0060 | 0.0229 | 0.0836 | 0.1434 | 0.0928 | 0.1261 | 0.5216 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 976 | 862 | | 8371 | 10040 | 119.6 | 44.92 | 155.74 | 155.70 | 66 | 82 | 94 | 104 | 115 | 126 | 139 | 155 | 180 | 0.1011 | 1015 | 0.966 | 89.94 | 27.51 | 4 | 0.0288 | 241 | 0.0007 | 62.88 | 7.556 | 0.1767 | 16326.4 | 2490000 | 417000000 | 75800000000 | 0.4543 | 0.2049 | 0.0006 | 0.0000 | 0.0058 | 0.0003 | 0.0252 | 0.0021 | 0.0659 | 0.0106 | 0.1494 | 0.0457 | 0.1923 | 0.0930 | 0.1593 | 0.0951 | 0.1636 | 0.1235 | 0.2379 | 0.6298 | 0.0002 | 0.0000 | 0.0010 | 0.0001 | 0.0033 | 0.0005 | 0.0121 | 0.0036 | 0.0500 | 0.0240 | 0.0668 | 0.0448 | 0.0596 | 0.0367 | 0.0870 | 0.0539 | 0.7200 | 0.8364 | 0.0009 | 0.0034 | 0.0035 | 0.0017 | 0.0132 | 0.0299 | 0.0475 | 0.0708 | 0.1174 | 0.1561 | 0.1500 | 0.1698 | 0.1047 | 0.0998 | 0.1341 | 0.1519 | 0.4288 | 0.3166 | 0.0011 | 0.0037 | 0.0045 | 0.0250 | 0.0677 | 0.1195 | 0.0937 | 0.1219 | 0.5629 | 15 | 25 | 47 | 74 | 107 | 150 | 200 | 260 | 359 | 0.0159 | 26.97 | 5.856 | 0.3967 | 48494.1 | 21800000 | 12600000000 | 8830000000000 | 0.5977 | 0.0835 | 0.0353 | 0.0018 | 0.1603 | 0.0185 | 0.3052 | 0.0912 | 0.1733 | 0.1119 | 0.1411 | 0.1866 | 0.1005 | 0.2165 | 0.0460 | 0.1263 | 0.0314 | 0.1278 | 0.0069 | 0.1193 | 0.0002 | 0.0006 | 0.0011 | 0.0009 | 0.0055 | 0.0039 | 0.0196 | 0.0131 | 0.0627 | 0.0586 | 0.1262 | 0.1037 | 0.0878 | 0.0736 | 0.1216 | 0.1085 | 0.5754 | 0.6371 | 0.0006 | 0.0030 | 0.0043 | 0.0059 | 0.0101 | 0.0111 | 0.0336 | 0.0392 | 0.0864 | 0.1103 | 0.1639 | 0.1799 | 0.1184 | 0.1136 | 0.1334 | 0.1358 | 0.4495 | 0.4012 | 0.0008 | 0.0015 | 0.0069 | 0.0240 | 0.0769 | 0.1428 | 0.0979 | 0.1329 | 0.5164 |