High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 484 | 784 | | 7556 | 23389 | 282.7 | 59.70 | 166.78 | 196.60 | 210 | 231 | 247 | 262 | 276 | 293 | 311 | 334 | 366 | 0.0490 | 1145 | 1.213 | 102.16 | 38.05 | 1 | 0.0335 | 253 | 0.0006 | 75.57 | 7.614 | 0.1408 | 83467.9 | 25700000 | 8220000000 | 2730000000000 | 0.4316 | 0.2191 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0020 | 0.0000 | 0.0170 | 0.0010 | 0.0677 | 0.0158 | 0.1511 | 0.0377 | 0.1521 | 0.0373 | 0.1708 | 0.0609 | 0.4384 | 0.8469 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0056 | 0.0004 | 0.0270 | 0.0106 | 0.0679 | 0.0232 | 0.0670 | 0.0160 | 0.0934 | 0.0265 | 0.7377 | 0.9233 | 0.0044 | 0.0233 | 0.0110 | 0.0233 | 0.0242 | 0.0631 | 0.0696 | 0.1728 | 0.1275 | 0.1960 | 0.1758 | 0.2060 | 0.1231 | 0.1063 | 0.1407 | 0.1296 | 0.3238 | 0.0797 | 0.0012 | 0.0035 | 0.0092 | 0.0372 | 0.0773 | 0.1330 | 0.1108 | 0.1304 | 0.4975 | 13 | 15 | 19 | 28 | 65 | 144 | 233 | 329 | 451 | 0.0382 | 38.04 | 5.638 | 0.4378 | 66466.3 | 34900000 | 21500000000 | 14900000000000 | 0.4729 | 0.1465 | 0.0850 | 0.0014 | 0.2309 | 0.0230 | 0.3225 | 0.1754 | 0.1274 | 0.1961 | 0.0928 | 0.2081 | 0.0531 | 0.1530 | 0.0330 | 0.0985 | 0.0279 | 0.0639 | 0.0274 | 0.0806 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0009 | 0.0009 | 0.0084 | 0.0061 | 0.0473 | 0.0406 | 0.0840 | 0.0716 | 0.0667 | 0.0537 | 0.1009 | 0.0862 | 0.6912 | 0.7406 | 0.0001 | 0.0001 | 0.0013 | 0.0011 | 0.0031 | 0.0056 | 0.0161 | 0.0217 | 0.0677 | 0.0724 | 0.1058 | 0.1268 | 0.0903 | 0.0954 | 0.1290 | 0.1366 | 0.5867 | 0.5403 | 0.0000 | 0.0011 | 0.0013 | 0.0122 | 0.0536 | 0.0968 | 0.0807 | 0.1121 | 0.6423 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 241 | 848 | | 10173 | 33400 | 558.7 | 106.36 | 141.20 | 210.07 | 440 | 469 | 494 | 517 | 539 | 564 | 595 | 638 | 721 | 0.0340 | 1136 | 1.181 | 125.88 | 48.08 | 1 | 0.0321 | 327 | 0.0010 | 33.71 | 7.169 | 0.1994 | 323447.0 | 194000000 | 121000000000 | 78500000000000 | 0.3999 | 0.2475 | 0.0004 | 0.0002 | 0.0009 | 0.0001 | 0.0027 | 0.0002 | 0.0123 | 0.0021 | 0.0344 | 0.0148 | 0.0701 | 0.0282 | 0.0822 | 0.0219 | 0.1201 | 0.0283 | 0.6769 | 0.9042 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0077 | 0.0002 | 0.0193 | 0.0092 | 0.0401 | 0.0151 | 0.0464 | 0.0088 | 0.0651 | 0.0146 | 0.8195 | 0.9521 | 0.0060 | 0.0020 | 0.0079 | 0.0101 | 0.0113 | 0.0061 | 0.0344 | 0.0869 | 0.0656 | 0.1212 | 0.0947 | 0.2222 | 0.0742 | 0.1253 | 0.0947 | 0.1616 | 0.6113 | 0.2646 | 0.0019 | 0.0063 | 0.0137 | 0.0288 | 0.0574 | 0.1020 | 0.0876 | 0.1004 | 0.6019 | 7 | 9 | 12 | 16 | 31 | 71 | 144 | 264 | 446 | 0.0759 | 52.63 | 5.308 | 0.4892 | 64064.9 | 41000000 | 31800000000 | 28400000000000 | 0.3985 | 0.2299 | 0.1332 | 0.0028 | 0.3108 | 0.0481 | 0.2982 | 0.2452 | 0.1039 | 0.2139 | 0.0716 | 0.1845 | 0.0484 | 0.1328 | 0.0222 | 0.0737 | 0.0081 | 0.0576 | 0.0035 | 0.0413 | 0.0002 | 0.0002 | 0.0008 | 0.0002 | 0.0013 | 0.0007 | 0.0107 | 0.0085 | 0.0677 | 0.0583 | 0.1067 | 0.0940 | 0.0684 | 0.0620 | 0.1038 | 0.0989 | 0.6404 | 0.6771 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0018 | 0.0038 | 0.0161 | 0.0195 | 0.0838 | 0.0907 | 0.1222 | 0.1354 | 0.0813 | 0.0869 | 0.1259 | 0.1305 | 0.5681 | 0.5326 | 0.0003 | 0.0006 | 0.0013 | 0.0134 | 0.0759 | 0.1150 | 0.0717 | 0.1123 | 0.6096 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 948 | 602 | | 5482 | 6626 | 431.8 | 96.54 | 133.95 | 147.02 | 321 | 351 | 372 | 394 | 415 | 441 | 472 | 515 | 567 | 0.1180 | 782 | 1.222 | 113.85 | 42.45 | 1 | 0.0520 | 285 | 0.0009 | 43.04 | 7.265 | 0.1744 | 195782.0 | 93200000 | 46500000000 | 24300000000000 | 0.4072 | 0.2460 | 0.0012 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0145 | 0.0012 | 0.0707 | 0.0208 | 0.1385 | 0.0387 | 0.1405 | 0.0363 | 0.1657 | 0.0562 | 0.4649 | 0.8469 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0056 | 0.0004 | 0.0357 | 0.0158 | 0.0655 | 0.0214 | 0.0748 | 0.0204 | 0.0919 | 0.0339 | 0.7240 | 0.9081 | 0.0029 | 0.0035 | 0.0029 | 0.0035 | 0.0095 | 0.0141 | 0.0475 | 0.0742 | 0.0846 | 0.1696 | 0.1454 | 0.2155 | 0.1055 | 0.1060 | 0.1084 | 0.1095 | 0.4933 | 0.3039 | 0.0021 | 0.0008 | 0.0119 | 0.0296 | 0.0716 | 0.1067 | 0.0809 | 0.0949 | 0.6014 | 11 | 15 | 23 | 44 | 79 | 120 | 169 | 238 | 356 | 0.0197 | 24.70 | 5.729 | 0.4245 | 39552.5 | 16000000 | 7850000000 | 4460000000000 | 0.4462 | 0.1848 | 0.0329 | 0.0007 | 0.1368 | 0.0059 | 0.2053 | 0.0553 | 0.2026 | 0.1211 | 0.1539 | 0.1895 | 0.1250 | 0.1914 | 0.0645 | 0.1303 | 0.0500 | 0.1375 | 0.0289 | 0.1684 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0012 | 0.0119 | 0.0055 | 0.0633 | 0.0525 | 0.0857 | 0.0756 | 0.0689 | 0.0619 | 0.1147 | 0.1026 | 0.6548 | 0.7008 | 0.0010 | 0.0017 | 0.0010 | 0.0017 | 0.0048 | 0.0039 | 0.0162 | 0.0231 | 0.0796 | 0.0732 | 0.0977 | 0.1082 | 0.0881 | 0.0890 | 0.1148 | 0.1104 | 0.5970 | 0.5887 | 0.0004 | 0.0000 | 0.0029 | 0.0139 | 0.0644 | 0.1076 | 0.0770 | 0.1129 | 0.6209 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 956 | 595 | | 1268 | 9881 | 91.4 | 16.59 | 53.65 | 107.18 | 71 | 75 | 80 | 84 | 89 | 95 | 101 | 108 | 115 | 0.0764 | 755 | 0.686 | 37.00 | 9.00 | 2 | 0.0694 | 88 | 0.0675 | 0.54 | 2.946 | 0.7664 | 8636.4 | 841834 | 84500000 | 8730000000 | 0.3820 | 0.2594 | 0.0034 | 0.0000 | 0.0101 | 0.0000 | 0.0190 | 0.0000 | 0.0324 | 0.0056 | 0.0738 | 0.0272 | 0.1309 | 0.0769 | 0.1119 | 0.0408 | 0.1644 | 0.0665 | 0.4541 | 0.7830 | 0.0027 | 0.0000 | 0.0063 | 0.0000 | 0.0081 | 0.0000 | 0.0181 | 0.0055 | 0.0433 | 0.0268 | 0.0668 | 0.0702 | 0.0542 | 0.0292 | 0.0713 | 0.0489 | 0.7292 | 0.8194 | 0.0140 | 0.0526 | 0.0047 | 0.0000 | 0.0607 | 0.0526 | 0.0467 | 0.1579 | 0.1215 | 0.4211 | 0.1449 | 0.1053 | 0.1402 | 0.0000 | 0.1869 | 0.1579 | 0.2804 | 0.0526 | 0.0017 | 0.0066 | 0.0150 | 0.0282 | 0.0465 | 0.0781 | 0.0880 | 0.0698 | 0.6661 | 5 | 7 | 8 | 10 | 13 | 24 | 48 | 81 | 142 | 0.0679 | 5.33 | 3.029 | 0.5252 | 14364.0 | 10100000 | 10700000000 | 13000000000000 | 0.4553 | 0.2110 | 0.0320 | 0.0021 | 0.1446 | 0.0121 | 0.2309 | 0.0605 | 0.2156 | 0.1517 | 0.1307 | 0.1944 | 0.1154 | 0.1830 | 0.0654 | 0.1161 | 0.0501 | 0.1061 | 0.0153 | 0.1738 | 0.0000 | 0.0000 | 0.0019 | 0.0003 | 0.0042 | 0.0040 | 0.0160 | 0.0130 | 0.0521 | 0.0454 | 0.0878 | 0.0802 | 0.0597 | 0.0519 | 0.0917 | 0.0918 | 0.6867 | 0.7134 | 0.0012 | 0.0009 | 0.0012 | 0.0019 | 0.0058 | 0.0047 | 0.0162 | 0.0160 | 0.0697 | 0.0782 | 0.1107 | 0.1097 | 0.0680 | 0.0763 | 0.1190 | 0.1266 | 0.6082 | 0.5857 | 0.0000 | 0.0029 | 0.0040 | 0.0169 | 0.0606 | 0.0948 | 0.0671 | 0.1168 | 0.6369 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 797 | 276 | | 3081 | 14857 | 257.1 | 73.60 | 95.99 | 124.19 | 175 | 187 | 202 | 218 | 241 | 266 | 296 | 325 | 367 | 0.0703 | 1045 | 0.709 | 60.54 | 16.03 | 2 | 0.0568 | 175 | 0.0097 | 3.01 | 5.047 | 0.5308 | 71538.3 | 21500000 | 6880000000 | 2330000000000 | 0.3683 | 0.2682 | 0.0023 | 0.0000 | 0.0053 | 0.0000 | 0.0107 | 0.0015 | 0.0328 | 0.0041 | 0.0710 | 0.0354 | 0.1154 | 0.0479 | 0.1054 | 0.0420 | 0.1398 | 0.0593 | 0.5172 | 0.8099 | 0.0014 | 0.0000 | 0.0019 | 0.0000 | 0.0043 | 0.0007 | 0.0125 | 0.0013 | 0.0288 | 0.0202 | 0.0389 | 0.0276 | 0.0408 | 0.0189 | 0.0504 | 0.0315 | 0.8209 | 0.8998 | 0.0013 | 0.0000 | 0.0000 | 0.0111 | 0.0090 | 0.0028 | 0.0168 | 0.0306 | 0.0530 | 0.0889 | 0.0917 | 0.1306 | 0.0646 | 0.1139 | 0.0904 | 0.1500 | 0.6731 | 0.4722 | 0.0015 | 0.0015 | 0.0052 | 0.0126 | 0.0238 | 0.0535 | 0.0416 | 0.0558 | 0.8045 | 12 | 19 | 29 | 42 | 54 | 70 | 95 | 135 | 230 | 0.0663 | 4.54 | 3.869 | 0.7237 | 24635.6 | 11400000 | 7270000000 | 5520000000000 | 0.4425 | 0.1810 | 0.0092 | 0.0039 | 0.0252 | 0.0102 | 0.0406 | 0.0158 | 0.0729 | 0.0304 | 0.1237 | 0.0621 | 0.1566 | 0.0900 | 0.1494 | 0.0954 | 0.1869 | 0.1280 | 0.2356 | 0.5641 | 0.0025 | 0.0017 | 0.0033 | 0.0049 | 0.0040 | 0.0052 | 0.0113 | 0.0100 | 0.0302 | 0.0240 | 0.0458 | 0.0344 | 0.0473 | 0.0408 | 0.0691 | 0.0611 | 0.7864 | 0.8179 | 0.0008 | 0.0007 | 0.0034 | 0.0027 | 0.0059 | 0.0050 | 0.0163 | 0.0174 | 0.0487 | 0.0557 | 0.0704 | 0.0795 | 0.0637 | 0.0651 | 0.0789 | 0.0849 | 0.7118 | 0.6890 | 0.0011 | 0.0052 | 0.0059 | 0.0142 | 0.0363 | 0.0542 | 0.0582 | 0.0716 | 0.7533 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 949 | 842 | | 9889 | 31538 | 604.3 | 116.89 | 203.51 | 321.81 | 475 | 511 | 538 | 562 | 585 | 611 | 645 | 691 | 761 | 0.0383 | 1208 | 0.571 | 106.00 | 25.06 | 1 | 0.0342 | 338 | 0.0006 | 73.38 | 7.682 | 0.1588 | 378894.0 | 247000000 | 168000000000 | 119000000000000 | 0.4171 | 0.2369 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0004 | 0.0074 | 0.0013 | 0.0446 | 0.0124 | 0.0828 | 0.0265 | 0.0975 | 0.0233 | 0.1253 | 0.0331 | 0.6398 | 0.9031 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0001 | 0.0032 | 0.0003 | 0.0237 | 0.0085 | 0.0410 | 0.0170 | 0.0490 | 0.0098 | 0.0664 | 0.0157 | 0.8162 | 0.9485 | 0.0014 | 0.0049 | 0.0084 | 0.0172 | 0.0274 | 0.0197 | 0.0556 | 0.1032 | 0.0985 | 0.1106 | 0.1343 | 0.1548 | 0.1069 | 0.1253 | 0.1153 | 0.1327 | 0.4522 | 0.3317 | 0.0012 | 0.0036 | 0.0092 | 0.0412 | 0.0736 | 0.1091 | 0.0992 | 0.1165 | 0.5465 | 8 | 9 | 12 | 17 | 48 | 103 | 192 | 355 | 647 | 0.1118 | 47.39 | 5.112 | 0.5378 | 144975.0 | 152000000 | 200000000000 | 309000000000000 | 0.3985 | 0.2132 | 0.0695 | 0.0027 | 0.2144 | 0.0263 | 0.2470 | 0.1596 | 0.1348 | 0.1210 | 0.1242 | 0.1636 | 0.0801 | 0.1770 | 0.0595 | 0.1103 | 0.0374 | 0.0928 | 0.0331 | 0.1466 | 0.0000 | 0.0001 | 0.0006 | 0.0005 | 0.0010 | 0.0014 | 0.0081 | 0.0074 | 0.0606 | 0.0447 | 0.0939 | 0.0785 | 0.0610 | 0.0514 | 0.0947 | 0.0842 | 0.6801 | 0.7319 | 0.0001 | 0.0003 | 0.0006 | 0.0005 | 0.0012 | 0.0012 | 0.0163 | 0.0192 | 0.0766 | 0.0837 | 0.1158 | 0.1356 | 0.0765 | 0.0760 | 0.1122 | 0.1199 | 0.6007 | 0.5636 | 0.0002 | 0.0005 | 0.0013 | 0.0122 | 0.0687 | 0.1051 | 0.0681 | 0.1068 | 0.6370 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 903 | 431 | | 54613 | 82874 | 84.8 | 46.65 | 114.00 | 205.41 | 23 | 28 | 54 | 73 | 87 | 99 | 112 | 126 | 146 | 0.0303 | 2514 | 0.607 | 231.82 | 52.47 | 24 | 0.0118 | 645 | 0.0046 | 13.65 | 6.351 | 0.3627 | 9367.0 | 1190000 | 165000000 | 24700000000 | 0.5125 | 0.1476 | 0.0017 | 0.0007 | 0.0076 | 0.0010 | 0.0380 | 0.0040 | 0.0801 | 0.0150 | 0.1435 | 0.0575 | 0.1828 | 0.1084 | 0.1675 | 0.1062 | 0.1626 | 0.1362 | 0.2163 | 0.5709 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0002 | 0.0055 | 0.0015 | 0.0213 | 0.0119 | 0.0388 | 0.0234 | 0.0374 | 0.0198 | 0.0551 | 0.0316 | 0.8399 | 0.9117 | 0.0006 | 0.0018 | 0.0028 | 0.0048 | 0.0065 | 0.0130 | 0.0229 | 0.0391 | 0.0576 | 0.0808 | 0.0882 | 0.1189 | 0.0857 | 0.0985 | 0.1117 | 0.1228 | 0.6241 | 0.5203 | 0.0004 | 0.0014 | 0.0040 | 0.0124 | 0.0339 | 0.0605 | 0.0589 | 0.0824 | 0.7461 | 10 | 12 | 13 | 15 | 18 | 26 | 61 | 174 | 383 | 0.2390 | 19.16 | 3.787 | 0.6638 | 55186.4 | 40400000 | 36400000000 | 37700000000000 | 0.4605 | 0.1949 | 0.1576 | 0.0035 | 0.3814 | 0.0611 | 0.3071 | 0.3277 | 0.0839 | 0.2234 | 0.0408 | 0.1726 | 0.0158 | 0.1086 | 0.0071 | 0.0487 | 0.0039 | 0.0298 | 0.0026 | 0.0245 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0008 | 0.0117 | 0.0106 | 0.0652 | 0.0602 | 0.1027 | 0.0939 | 0.0640 | 0.0575 | 0.0983 | 0.0881 | 0.6561 | 0.6885 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0020 | 0.0025 | 0.0164 | 0.0184 | 0.0742 | 0.0778 | 0.1173 | 0.1225 | 0.0764 | 0.0817 | 0.1085 | 0.1098 | 0.6044 | 0.5860 | 0.0001 | 0.0002 | 0.0017 | 0.0132 | 0.0722 | 0.1105 | 0.0693 | 0.1056 | 0.6272 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 376 | 455 | | 8612 | 19511 | 469.8 | 86.38 | 153.43 | 207.66 | 366 | 398 | 421 | 442 | 462 | 481 | 504 | 535 | 586 | 0.0560 | 1092 | 1.054 | 96.75 | 36.14 | 2 | 0.0303 | 261 | 0.0021 | 17.56 | 6.482 | 0.2579 | 228217.0 | 115000000 | 59600000000 | 32000000000000 | 0.4229 | 0.2282 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0001 | 0.0076 | 0.0005 | 0.0416 | 0.0131 | 0.0841 | 0.0274 | 0.0978 | 0.0207 | 0.1278 | 0.0313 | 0.6396 | 0.9068 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0041 | 0.0000 | 0.0211 | 0.0100 | 0.0414 | 0.0175 | 0.0481 | 0.0110 | 0.0610 | 0.0179 | 0.8237 | 0.9436 | 0.0043 | 0.0036 | 0.0120 | 0.0109 | 0.0197 | 0.0217 | 0.0557 | 0.0833 | 0.1259 | 0.1304 | 0.1430 | 0.2319 | 0.1062 | 0.1196 | 0.1233 | 0.1159 | 0.4101 | 0.2826 | 0.0015 | 0.0043 | 0.0089 | 0.0317 | 0.0735 | 0.1259 | 0.1036 | 0.1315 | 0.5193 | 11 | 13 | 18 | 30 | 60 | 112 | 179 | 264 | 423 | 0.0683 | 25.53 | 5.187 | 0.5116 | 66658.4 | 44800000 | 39000000000 | 40100000000000 | 0.5736 | 0.1127 | 0.0353 | 0.0020 | 0.1686 | 0.0088 | 0.3001 | 0.0775 | 0.1811 | 0.1460 | 0.1407 | 0.2098 | 0.0974 | 0.2095 | 0.0444 | 0.1320 | 0.0256 | 0.1163 | 0.0068 | 0.0981 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0009 | 0.0008 | 0.0093 | 0.0073 | 0.0635 | 0.0515 | 0.0934 | 0.0789 | 0.0696 | 0.0596 | 0.1069 | 0.0928 | 0.6562 | 0.7087 | 0.0009 | 0.0006 | 0.0016 | 0.0028 | 0.0024 | 0.0028 | 0.0164 | 0.0188 | 0.0739 | 0.0858 | 0.1294 | 0.1377 | 0.0880 | 0.0928 | 0.1272 | 0.1341 | 0.5603 | 0.5246 | 0.0002 | 0.0006 | 0.0021 | 0.0135 | 0.0685 | 0.1068 | 0.0784 | 0.1212 | 0.6087 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1226 | 292 | | 1447 | 9024 | 65.1 | 24.28 | 181.44 | 210.82 | 35 | 44 | 51 | 57 | 63 | 69 | 76 | 85 | 96 | 0.0659 | 595 | 0.521 | 83.49 | 16.03 | 5 | 0.1714 | 248 | 0.0021 | 31.10 | 6.361 | 0.2003 | 4823.6 | 400876 | 37000000 | 3760000000 | 0.3867 | 0.2406 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0198 | 0.0028 | 0.0843 | 0.0170 | 0.1802 | 0.0405 | 0.2215 | 0.1008 | 0.1884 | 0.1329 | 0.1818 | 0.1951 | 0.1124 | 0.5108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0016 | 0.0109 | 0.0095 | 0.0465 | 0.0247 | 0.0812 | 0.0366 | 0.0663 | 0.0461 | 0.1238 | 0.0700 | 0.6693 | 0.8115 | 0.0049 | 0.0255 | 0.0099 | 0.0204 | 0.0025 | 0.0510 | 0.0765 | 0.1071 | 0.1284 | 0.1837 | 0.1778 | 0.1735 | 0.1654 | 0.1173 | 0.1407 | 0.1378 | 0.2938 | 0.1837 | 0.0015 | 0.0029 | 0.0059 | 0.0322 | 0.1025 | 0.1259 | 0.1127 | 0.1347 | 0.4817 | 19 | 26 | 41 | 64 | 97 | 142 | 205 | 308 | 477 | 0.0338 | 9.96 | 5.000 | 0.5659 | 77361.5 | 47900000 | 36100000000 | 30600000000000 | 0.5191 | 0.1524 | 0.0220 | 0.0015 | 0.0828 | 0.0094 | 0.1118 | 0.0342 | 0.1577 | 0.0768 | 0.2126 | 0.1412 | 0.1427 | 0.1684 | 0.1228 | 0.1273 | 0.0918 | 0.1446 | 0.0559 | 0.2967 | 0.0006 | 0.0005 | 0.0025 | 0.0012 | 0.0034 | 0.0009 | 0.0104 | 0.0092 | 0.0533 | 0.0431 | 0.0855 | 0.0726 | 0.0676 | 0.0528 | 0.0917 | 0.0820 | 0.6851 | 0.7378 | 0.0008 | 0.0013 | 0.0027 | 0.0022 | 0.0059 | 0.0040 | 0.0164 | 0.0211 | 0.0632 | 0.0723 | 0.1096 | 0.1159 | 0.0780 | 0.0858 | 0.1166 | 0.1204 | 0.6069 | 0.5768 | 0.0003 | 0.0020 | 0.0043 | 0.0143 | 0.0627 | 0.0953 | 0.0720 | 0.1040 | 0.6450 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 420 | 407 | | 25302 | 42176 | 171.8 | 49.38 | 147.43 | 237.23 | 112 | 132 | 146 | 157 | 168 | 180 | 193 | 209 | 237 | 0.0462 | 1948 | 0.760 | 83.49 | 25.63 | 2 | 0.0098 | 247 | 0.0005 | 62.65 | 7.913 | 0.1534 | 31965.7 | 6390000 | 1360000000 | 309000000000 | 0.4638 | 0.1892 | 0.0006 | 0.0001 | 0.0017 | 0.0002 | 0.0040 | 0.0010 | 0.0225 | 0.0052 | 0.0688 | 0.0183 | 0.1379 | 0.0386 | 0.1421 | 0.0455 | 0.1734 | 0.0654 | 0.4489 | 0.8256 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0012 | 0.0003 | 0.0082 | 0.0023 | 0.0254 | 0.0102 | 0.0549 | 0.0202 | 0.0570 | 0.0218 | 0.0776 | 0.0313 | 0.7745 | 0.9136 | 0.0031 | 0.0052 | 0.0063 | 0.0083 | 0.0203 | 0.0270 | 0.0520 | 0.0513 | 0.0941 | 0.0896 | 0.1249 | 0.1265 | 0.0922 | 0.0926 | 0.1087 | 0.1087 | 0.4984 | 0.4909 | 0.0012 | 0.0029 | 0.0075 | 0.0285 | 0.0609 | 0.0972 | 0.0953 | 0.1135 | 0.5931 | 15 | 18 | 20 | 25 | 35 | 63 | 116 | 226 | 460 | 0.1298 | 9.91 | 4.162 | 0.6635 | 78010.9 | 64000000 | 64700000000 | 75200000000000 | 0.5804 | 0.1109 | 0.0461 | 0.0048 | 0.1404 | 0.0150 | 0.1993 | 0.0735 | 0.1444 | 0.1068 | 0.1579 | 0.1632 | 0.1301 | 0.1918 | 0.0879 | 0.1258 | 0.0525 | 0.1221 | 0.0414 | 0.1970 | 0.0003 | 0.0004 | 0.0022 | 0.0006 | 0.0037 | 0.0016 | 0.0126 | 0.0129 | 0.0488 | 0.0445 | 0.0771 | 0.0675 | 0.0547 | 0.0498 | 0.0753 | 0.0744 | 0.7252 | 0.7484 | 0.0003 | 0.0004 | 0.0020 | 0.0030 | 0.0029 | 0.0043 | 0.0165 | 0.0197 | 0.0624 | 0.0647 | 0.0891 | 0.0998 | 0.0647 | 0.0673 | 0.0892 | 0.0949 | 0.6728 | 0.6458 | 0.0008 | 0.0012 | 0.0033 | 0.0140 | 0.0563 | 0.0848 | 0.0591 | 0.0848 | 0.6958 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 618 | 706 | | 10617 | 14965 | 406.0 | 74.21 | 106.42 | 146.05 | 301 | 340 | 368 | 390 | 410 | 428 | 446 | 467 | 497 | 0.0708 | 1060 | 1.136 | 84.60 | 28.00 | 1 | 0.0195 | 207 | 0.0009 | 31.67 | 7.285 | 0.2045 | 170377.0 | 73700000 | 32700000000 | 14900000000000 | 0.4237 | 0.2226 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0002 | 0.0088 | 0.0007 | 0.0302 | 0.0106 | 0.0672 | 0.0224 | 0.0738 | 0.0182 | 0.1228 | 0.0277 | 0.6938 | 0.9203 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0001 | 0.0037 | 0.0004 | 0.0152 | 0.0092 | 0.0270 | 0.0175 | 0.0239 | 0.0109 | 0.0406 | 0.0156 | 0.8882 | 0.9463 | 0.0126 | 0.0000 | 0.0223 | 0.0000 | 0.0334 | 0.0000 | 0.0713 | 0.0000 | 0.1166 | 0.0000 | 0.1308 | 0.0000 | 0.1010 | 0.0000 | 0.1337 | 0.0000 | 0.3782 | 0.0000 | 0.0016 | 0.0018 | 0.0038 | 0.0148 | 0.0460 | 0.0748 | 0.0780 | 0.1090 | 0.6702 | 14 | 17 | 21 | 27 | 38 | 57 | 93 | 167 | 327 | 0.0504 | 11.32 | 4.608 | 0.5968 | 32654.3 | 14800000 | 7870000000 | 4610000000000 | 0.5804 | 0.0982 | 0.0354 | 0.0029 | 0.1407 | 0.0100 | 0.2405 | 0.0716 | 0.1506 | 0.1194 | 0.1370 | 0.1573 | 0.0962 | 0.1935 | 0.0762 | 0.1149 | 0.0681 | 0.1036 | 0.0554 | 0.2268 | 0.0006 | 0.0011 | 0.0011 | 0.0011 | 0.0034 | 0.0037 | 0.0120 | 0.0134 | 0.0582 | 0.0461 | 0.0881 | 0.0767 | 0.0586 | 0.0530 | 0.0837 | 0.0788 | 0.6943 | 0.7262 | 0.0000 | 0.0003 | 0.0011 | 0.0012 | 0.0027 | 0.0049 | 0.0165 | 0.0172 | 0.0692 | 0.0712 | 0.1000 | 0.1157 | 0.0744 | 0.0740 | 0.1085 | 0.1074 | 0.6276 | 0.6080 | 0.0005 | 0.0005 | 0.0019 | 0.0150 | 0.0645 | 0.0978 | 0.0619 | 0.1022 | 0.6557 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1195 | 448 | | 4077 | 9038 | 310.9 | 53.86 | 181.75 | 300.58 | 243 | 263 | 279 | 292 | 306 | 323 | 341 | 360 | 384 | 0.0823 | 744 | 0.923 | 64.47 | 17.49 | 1 | 0.0373 | 152 | 0.0015 | 24.49 | 6.739 | 0.2284 | 99584.3 | 32800000 | 11100000000 | 3850000000000 | 0.4223 | 0.2256 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0002 | 0.0166 | 0.0005 | 0.0445 | 0.0156 | 0.0831 | 0.0297 | 0.0950 | 0.0225 | 0.1292 | 0.0312 | 0.6276 | 0.9002 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0014 | 0.0002 | 0.0081 | 0.0005 | 0.0209 | 0.0152 | 0.0345 | 0.0258 | 0.0376 | 0.0142 | 0.0585 | 0.0219 | 0.8387 | 0.9222 | 0.0069 | 0.0000 | 0.0086 | 0.0000 | 0.0293 | 0.0000 | 0.0810 | 0.0000 | 0.1207 | 0.0000 | 0.1828 | 0.0000 | 0.1293 | 0.0000 | 0.1483 | 0.0000 | 0.2931 | 0.0000 | 0.0026 | 0.0021 | 0.0057 | 0.0188 | 0.0490 | 0.0834 | 0.0870 | 0.1021 | 0.6493 | 19 | 24 | 31 | 45 | 71 | 99 | 135 | 242 | 489 | 0.0344 | 32.85 | 5.199 | 0.5254 | 123371.0 | 146000000 | 217000000000 | 363000000000000 | 0.4937 | 0.1466 | 0.0515 | 0.0058 | 0.1530 | 0.0187 | 0.2641 | 0.0515 | 0.1578 | 0.1120 | 0.1401 | 0.1552 | 0.1014 | 0.1964 | 0.0354 | 0.1365 | 0.0290 | 0.1223 | 0.0676 | 0.2015 | 0.0012 | 0.0021 | 0.0063 | 0.0021 | 0.0067 | 0.0027 | 0.0185 | 0.0209 | 0.0653 | 0.0581 | 0.1034 | 0.0877 | 0.0594 | 0.0714 | 0.0975 | 0.1025 | 0.6418 | 0.6525 | 0.0005 | 0.0000 | 0.0010 | 0.0023 | 0.0031 | 0.0029 | 0.0166 | 0.0165 | 0.0786 | 0.0764 | 0.0994 | 0.1107 | 0.0708 | 0.0696 | 0.1124 | 0.1095 | 0.6176 | 0.6121 | 0.0000 | 0.0014 | 0.0023 | 0.0148 | 0.0696 | 0.1035 | 0.0650 | 0.1072 | 0.6362 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1140 | 503 | | 4025 | 13483 | 436.8 | 85.79 | 132.10 | 242.48 | 338 | 368 | 391 | 415 | 440 | 463 | 488 | 513 | 540 | 0.0518 | 698 | 1.105 | 49.03 | 18.38 | 2 | 0.0330 | 133 | 0.0012 | 33.18 | 6.972 | 0.2087 | 198109.0 | 92600000 | 44400000000 | 21800000000000 | 0.4526 | 0.1884 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0035 | 0.0000 | 0.0139 | 0.0010 | 0.0522 | 0.0198 | 0.1099 | 0.0311 | 0.0967 | 0.0257 | 0.1398 | 0.0363 | 0.5819 | 0.8861 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0005 | 0.0267 | 0.0189 | 0.0517 | 0.0288 | 0.0402 | 0.0186 | 0.0577 | 0.0283 | 0.8190 | 0.9049 | 0.0050 | 0.0000 | 0.0033 | 0.0606 | 0.0429 | 0.1515 | 0.0759 | 0.2121 | 0.1188 | 0.1212 | 0.1914 | 0.2424 | 0.1452 | 0.1515 | 0.1551 | 0.0303 | 0.2624 | 0.0303 | 0.0005 | 0.0024 | 0.0058 | 0.0169 | 0.0551 | 0.0851 | 0.0807 | 0.1054 | 0.6481 | 6 | 7 | 9 | 10 | 14 | 25 | 74 | 196 | 483 | 0.1545 | 27.57 | 4.157 | 0.6237 | 76242.5 | 60100000 | 54300000000 | 53300000000000 | 0.5764 | 0.1021 | 0.0301 | 0.0017 | 0.1284 | 0.0108 | 0.1997 | 0.0687 | 0.1458 | 0.1026 | 0.1838 | 0.1745 | 0.1331 | 0.1977 | 0.0666 | 0.1266 | 0.0602 | 0.1290 | 0.0523 | 0.1886 | 0.0003 | 0.0000 | 0.0005 | 0.0008 | 0.0025 | 0.0013 | 0.0066 | 0.0078 | 0.0442 | 0.0373 | 0.0700 | 0.0607 | 0.0437 | 0.0396 | 0.0626 | 0.0595 | 0.7696 | 0.7931 | 0.0000 | 0.0014 | 0.0013 | 0.0014 | 0.0027 | 0.0036 | 0.0166 | 0.0159 | 0.0525 | 0.0587 | 0.0807 | 0.0844 | 0.0558 | 0.0543 | 0.0751 | 0.0736 | 0.7153 | 0.7065 | 0.0003 | 0.0012 | 0.0033 | 0.0100 | 0.0504 | 0.0697 | 0.0573 | 0.0733 | 0.7346 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1249 | 769 | | 4803 | 11247 | 502.2 | 83.00 | 67.05 | 122.38 | 382 | 431 | 463 | 488 | 508 | 528 | 552 | 579 | 608 | 0.0648 | 729 | 1.156 | 88.46 | 33.06 | 1 | 0.0477 | 229 | 0.0014 | 23.98 | 6.830 | 0.2358 | 259094.0 | 137000000 | 73800000000 | 40500000000000 | 0.4284 | 0.2133 | 0.0011 | 0.0000 | 0.0019 | 0.0000 | 0.0044 | 0.0000 | 0.0091 | 0.0002 | 0.0299 | 0.0136 | 0.0517 | 0.0206 | 0.0575 | 0.0124 | 0.0811 | 0.0183 | 0.7632 | 0.9350 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0002 | 0.0170 | 0.0136 | 0.0276 | 0.0206 | 0.0218 | 0.0124 | 0.0377 | 0.0183 | 0.8937 | 0.9350 | 0.0072 | 0.0000 | 0.0181 | 0.0000 | 0.0325 | 0.0000 | 0.0597 | 0.0000 | 0.0868 | 0.0000 | 0.1374 | 0.0000 | 0.1230 | 0.0000 | 0.1754 | 0.0000 | 0.3599 | 0.0000 | 0.0019 | 0.0016 | 0.0054 | 0.0140 | 0.0384 | 0.0594 | 0.0602 | 0.0889 | 0.7301 | 6 | 8 | 10 | 12 | 15 | 20 | 38 | 86 | 207 | 0.1665 | 6.51 | 3.350 | 0.6502 | 19470.7 | 8860000 | 4860000000 | 2970000000000 | 0.5816 | 0.0962 | 0.0324 | 0.0043 | 0.1477 | 0.0208 | 0.2216 | 0.0720 | 0.2090 | 0.1276 | 0.1658 | 0.1753 | 0.1189 | 0.1840 | 0.0613 | 0.1372 | 0.0216 | 0.1345 | 0.0216 | 0.1441 | 0.0007 | 0.0003 | 0.0010 | 0.0009 | 0.0034 | 0.0039 | 0.0172 | 0.0128 | 0.0540 | 0.0538 | 0.0890 | 0.0805 | 0.0639 | 0.0589 | 0.0907 | 0.0838 | 0.6801 | 0.7050 | 0.0000 | 0.0005 | 0.0013 | 0.0019 | 0.0030 | 0.0033 | 0.0166 | 0.0196 | 0.0675 | 0.0650 | 0.0968 | 0.1182 | 0.0739 | 0.0715 | 0.0994 | 0.1005 | 0.6416 | 0.6196 | 0.0004 | 0.0015 | 0.0034 | 0.0145 | 0.0574 | 0.1015 | 0.0624 | 0.0915 | 0.6673 | ||
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1083 | 712 | | 14567 | 23345 | 228.3 | 65.80 | 245.84 | 294.83 | 149 | 171 | 189 | 204 | 221 | 238 | 259 | 283 | 318 | 0.0544 | 1269 | 0.975 | 95.05 | 27.31 | 2 | 0.0162 | 236 | 0.0009 | 39.78 | 7.247 | 0.1948 | 56452.3 | 15000000 | 4270000000 | 1290000000000 | 0.4024 | 0.2555 | 0.0004 | 0.0000 | 0.0033 | 0.0002 | 0.0132 | 0.0010 | 0.0356 | 0.0063 | 0.1124 | 0.0290 | 0.1854 | 0.0626 | 0.1649 | 0.0652 | 0.1702 | 0.0924 | 0.3145 | 0.7434 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0102 | 0.0020 | 0.0384 | 0.0138 | 0.0759 | 0.0319 | 0.0663 | 0.0284 | 0.0851 | 0.0426 | 0.7219 | 0.8812 | 0.0023 | 0.0036 | 0.0040 | 0.0136 | 0.0144 | 0.0300 | 0.0586 | 0.0886 | 0.1114 | 0.1671 | 0.1697 | 0.2064 | 0.1117 | 0.1207 | 0.1400 | 0.1486 | 0.3879 | 0.2214 | 0.0012 | 0.0012 | 0.0051 | 0.0274 | 0.0791 | 0.1243 | 0.1042 | 0.1238 | 0.5337 | 8 | 10 | 17 | 42 | 109 | 218 | 349 | 492 | 669 | 0.0408 | 47.90 | 5.810 | 0.3933 | 147362.0 | 116000000 | 111000000000 | 123000000000000 | 0.4697 | 0.1864 | 0.1067 | 0.0030 | 0.2767 | 0.0213 | 0.3109 | 0.2024 | 0.1380 | 0.1983 | 0.0764 | 0.2125 | 0.0525 | 0.1566 | 0.0183 | 0.0876 | 0.0165 | 0.0554 | 0.0040 | 0.0630 | 0.0002 | 0.0001 | 0.0000 | 0.0000 | 0.0009 | 0.0008 | 0.0096 | 0.0068 | 0.0596 | 0.0493 | 0.0934 | 0.0808 | 0.0646 | 0.0569 | 0.0998 | 0.0835 | 0.6719 | 0.7217 | 0.0000 | 0.0001 | 0.0005 | 0.0000 | 0.0016 | 0.0021 | 0.0167 | 0.0199 | 0.0781 | 0.0907 | 0.1165 | 0.1342 | 0.0867 | 0.0938 | 0.1227 | 0.1335 | 0.5771 | 0.5256 | 0.0000 | 0.0001 | 0.0009 | 0.0116 | 0.0678 | 0.1051 | 0.0737 | 0.1126 | 0.6282 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 355 | 746 | | 5178 | 14618 | 327.7 | 65.14 | 129.72 | 168.91 | 250 | 272 | 289 | 304 | 321 | 339 | 359 | 383 | 416 | 0.0483 | 706 | 1.223 | 132.20 | 48.33 | 1 | 0.0624 | 323 | 0.0006 | 79.47 | 7.577 | 0.1347 | 111643.0 | 39500000 | 14500000000 | 5500000000000 | 0.4016 | 0.2477 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0000 | 0.0124 | 0.0010 | 0.0615 | 0.0141 | 0.1154 | 0.0278 | 0.1391 | 0.0377 | 0.1708 | 0.0498 | 0.4976 | 0.8695 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0048 | 0.0006 | 0.0275 | 0.0103 | 0.0562 | 0.0177 | 0.0558 | 0.0168 | 0.0767 | 0.0242 | 0.7779 | 0.9305 | 0.0000 | 0.0057 | 0.0082 | 0.0341 | 0.0411 | 0.0625 | 0.0799 | 0.1591 | 0.1246 | 0.1932 | 0.1669 | 0.1648 | 0.1269 | 0.1193 | 0.1504 | 0.1307 | 0.3020 | 0.1307 | 0.0025 | 0.0038 | 0.0046 | 0.0302 | 0.0772 | 0.1234 | 0.1083 | 0.1318 | 0.5183 | 11 | 13 | 15 | 20 | 32 | 75 | 158 | 264 | 389 | 0.0486 | 32.17 | 5.262 | 0.4801 | 45355.6 | 21000000 | 11400000000 | 6870000000000 | 0.5030 | 0.1599 | 0.1206 | 0.0006 | 0.3330 | 0.0356 | 0.3146 | 0.2808 | 0.1079 | 0.2475 | 0.0769 | 0.1991 | 0.0321 | 0.1068 | 0.0115 | 0.0595 | 0.0023 | 0.0473 | 0.0011 | 0.0228 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0117 | 0.0095 | 0.0635 | 0.0521 | 0.0928 | 0.0937 | 0.0628 | 0.0577 | 0.1074 | 0.0968 | 0.6595 | 0.6891 | 0.0007 | 0.0007 | 0.0007 | 0.0015 | 0.0029 | 0.0020 | 0.0167 | 0.0162 | 0.0625 | 0.0729 | 0.1186 | 0.1226 | 0.0783 | 0.0896 | 0.1208 | 0.1300 | 0.5988 | 0.5646 | 0.0000 | 0.0002 | 0.0037 | 0.0165 | 0.0591 | 0.1021 | 0.0779 | 0.1118 | 0.6285 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 771 | 729 | | 699 | 8074 | 51.0 | 15.12 | 134.99 | 188.23 | 31 | 35 | 40 | 45 | 50 | 56 | 62 | 67 | 72 | 0.0588 | 475 | 1.025 | 40.01 | 10.20 | 1 | 0.1373 | 96 | 0.0059 | 6.82 | 5.319 | 0.3605 | 2826.1 | 167621 | 10500000 | 678000000 | 0.3593 | 0.2671 | 0.0074 | 0.0000 | 0.0223 | 0.0106 | 0.0186 | 0.0195 | 0.0483 | 0.0283 | 0.1264 | 0.0496 | 0.1561 | 0.0637 | 0.1822 | 0.0991 | 0.2119 | 0.1558 | 0.2268 | 0.5735 | 0.0000 | 0.0000 | 0.0021 | 0.0016 | 0.0021 | 0.0094 | 0.0125 | 0.0141 | 0.0480 | 0.0297 | 0.0438 | 0.0375 | 0.0438 | 0.0531 | 0.0710 | 0.0688 | 0.7766 | 0.7859 | 0.0000 | 0.0267 | 0.0095 | 0.0533 | 0.0095 | 0.0533 | 0.0714 | 0.1867 | 0.0571 | 0.1333 | 0.0857 | 0.2000 | 0.1333 | 0.1733 | 0.1762 | 0.1467 | 0.4571 | 0.0267 | 0.0000 | 0.0029 | 0.0086 | 0.0201 | 0.0430 | 0.0630 | 0.0516 | 0.0860 | 0.7249 | 17 | 20 | 22 | 27 | 42 | 69 | 121 | 231 | 414 | 0.1036 | 10.05 | 4.238 | 0.6273 | 53649.5 | 30800000 | 20700000000 | 15500000000000 | 0.6068 | 0.0942 | 0.0493 | 0.0037 | 0.1637 | 0.0266 | 0.2249 | 0.1322 | 0.1657 | 0.1506 | 0.1400 | 0.1304 | 0.1183 | 0.1680 | 0.0552 | 0.1074 | 0.0414 | 0.0973 | 0.0414 | 0.1837 | 0.0004 | 0.0007 | 0.0012 | 0.0013 | 0.0046 | 0.0030 | 0.0150 | 0.0167 | 0.0547 | 0.0407 | 0.0875 | 0.0781 | 0.0586 | 0.0524 | 0.0848 | 0.0851 | 0.6933 | 0.7219 | 0.0005 | 0.0005 | 0.0019 | 0.0042 | 0.0043 | 0.0100 | 0.0168 | 0.0173 | 0.0570 | 0.0614 | 0.1049 | 0.0992 | 0.0608 | 0.0719 | 0.0967 | 0.1028 | 0.6571 | 0.6327 | 0.0000 | 0.0039 | 0.0035 | 0.0195 | 0.0500 | 0.0925 | 0.0626 | 0.0947 | 0.6733 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 200 | 513 | | 11296 | 11224 | 660.4 | 94.02 | 95.02 | 136.71 | 543 | 587 | 617 | 640 | 661 | 683 | 708 | 735 | 774 | 0.1009 | 1133 | 0.918 | 133.74 | 44.91 | 2 | 0.0313 | 353 | 0.0006 | 79.90 | 7.739 | 0.1635 | 444990.0 | 305000000 | 213000000000 | 152000000000000 | 0.4251 | 0.2228 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0042 | 0.0006 | 0.0187 | 0.0081 | 0.0399 | 0.0182 | 0.0436 | 0.0113 | 0.0656 | 0.0181 | 0.8257 | 0.9436 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0022 | 0.0004 | 0.0107 | 0.0077 | 0.0240 | 0.0167 | 0.0219 | 0.0084 | 0.0314 | 0.0139 | 0.9090 | 0.9530 | 0.0074 | 0.0816 | 0.0173 | 0.0204 | 0.0222 | 0.0408 | 0.0937 | 0.2245 | 0.0912 | 0.2245 | 0.1307 | 0.2041 | 0.1097 | 0.0816 | 0.1233 | 0.1224 | 0.4044 | 0.0000 | 0.0016 | 0.0026 | 0.0092 | 0.0209 | 0.0527 | 0.0772 | 0.0800 | 0.1071 | 0.6486 | 12 | 16 | 20 | 27 | 38 | 53 | 81 | 138 | 272 | 0.0564 | 8.94 | 4.344 | 0.6275 | 27717.6 | 13300000 | 8080000000 | 5720000000000 | 0.4886 | 0.1747 | 0.0110 | 0.0020 | 0.0386 | 0.0109 | 0.0684 | 0.0288 | 0.1323 | 0.0387 | 0.2183 | 0.1107 | 0.1940 | 0.1846 | 0.1147 | 0.1166 | 0.1422 | 0.1509 | 0.0805 | 0.3568 | 0.0009 | 0.0007 | 0.0031 | 0.0037 | 0.0037 | 0.0072 | 0.0119 | 0.0120 | 0.0417 | 0.0400 | 0.0716 | 0.0744 | 0.0409 | 0.0423 | 0.0707 | 0.0596 | 0.7555 | 0.7601 | 0.0008 | 0.0004 | 0.0011 | 0.0022 | 0.0042 | 0.0043 | 0.0168 | 0.0173 | 0.0348 | 0.0381 | 0.0880 | 0.0934 | 0.0513 | 0.0510 | 0.0677 | 0.0636 | 0.7353 | 0.7297 | 0.0007 | 0.0010 | 0.0036 | 0.0116 | 0.0416 | 0.0819 | 0.0459 | 0.0714 | 0.7423 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 662 | 697 | | 5913 | 18261 | 491.0 | 67.94 | 138.35 | 220.58 | 396 | 436 | 462 | 484 | 500 | 513 | 528 | 544 | 572 | 0.0451 | 824 | 1.176 | 94.54 | 34.99 | 1 | 0.0404 | 239 | 0.0021 | 16.68 | 6.549 | 0.2788 | 245703.0 | 125000000 | 64600000000 | 33900000000000 | 0.4193 | 0.2254 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0002 | 0.0206 | 0.0107 | 0.0401 | 0.0231 | 0.0409 | 0.0105 | 0.0497 | 0.0178 | 0.8421 | 0.9378 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0011 | 0.0002 | 0.0140 | 0.0105 | 0.0257 | 0.0222 | 0.0200 | 0.0095 | 0.0276 | 0.0162 | 0.9112 | 0.9414 | 0.0028 | 0.0000 | 0.0142 | 0.1111 | 0.0426 | 0.1111 | 0.0767 | 0.1111 | 0.1392 | 0.4444 | 0.1193 | 0.2222 | 0.1193 | 0.0000 | 0.1591 | 0.0000 | 0.3267 | 0.0000 | 0.0003 | 0.0033 | 0.0069 | 0.0169 | 0.0350 | 0.0555 | 0.0628 | 0.0872 | 0.7320 | 8 | 10 | 12 | 16 | 27 | 52 | 112 | 246 | 464 | 0.1339 | 21.44 | 4.364 | 0.6125 | 67793.0 | 46900000 | 38600000000 | 36000000000000 | 0.3682 | 0.2671 | 0.0646 | 0.0035 | 0.1579 | 0.0234 | 0.2759 | 0.1034 | 0.1692 | 0.1313 | 0.1344 | 0.1895 | 0.0985 | 0.2004 | 0.0595 | 0.1034 | 0.0236 | 0.1193 | 0.0164 | 0.1258 | 0.0004 | 0.0006 | 0.0011 | 0.0015 | 0.0025 | 0.0023 | 0.0114 | 0.0085 | 0.0461 | 0.0447 | 0.0764 | 0.0614 | 0.0517 | 0.0432 | 0.0719 | 0.0705 | 0.7384 | 0.7673 | 0.0011 | 0.0005 | 0.0009 | 0.0007 | 0.0026 | 0.0033 | 0.0168 | 0.0158 | 0.0521 | 0.0575 | 0.0907 | 0.0945 | 0.0618 | 0.0628 | 0.0783 | 0.0833 | 0.6958 | 0.6816 | 0.0006 | 0.0014 | 0.0028 | 0.0152 | 0.0474 | 0.0861 | 0.0548 | 0.0734 | 0.7183 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 536 | 592 | | 11784 | 41678 | 115.6 | 34.59 | 207.83 | 214.61 | 75 | 86 | 94 | 103 | 111 | 120 | 130 | 144 | 163 | 0.0416 | 1732 | 0.727 | 154.55 | 39.40 | 3 | 0.0386 | 455 | 0.0021 | 19.63 | 6.518 | 0.2766 | 14550.8 | 1990000 | 293000000 | 46400000000 | 0.4899 | 0.1699 | 0.0021 | 0.0004 | 0.0048 | 0.0007 | 0.0141 | 0.0032 | 0.0416 | 0.0077 | 0.1062 | 0.0329 | 0.1621 | 0.0738 | 0.1591 | 0.0708 | 0.1647 | 0.0991 | 0.3453 | 0.7113 | 0.0007 | 0.0001 | 0.0018 | 0.0005 | 0.0040 | 0.0013 | 0.0122 | 0.0039 | 0.0406 | 0.0176 | 0.0687 | 0.0392 | 0.0628 | 0.0280 | 0.0796 | 0.0464 | 0.7295 | 0.8631 | 0.0022 | 0.0025 | 0.0041 | 0.0115 | 0.0137 | 0.0329 | 0.0504 | 0.0873 | 0.1067 | 0.1853 | 0.1530 | 0.1919 | 0.1278 | 0.1227 | 0.1467 | 0.1524 | 0.3956 | 0.2133 | 0.0013 | 0.0036 | 0.0085 | 0.0266 | 0.0690 | 0.1142 | 0.0929 | 0.1140 | 0.5699 | 15 | 20 | 37 | 80 | 139 | 203 | 278 | 375 | 515 | 0.0215 | 74.38 | 6.685 | 0.3397 | 89248.9 | 51000000 | 34800000000 | 27200000000000 | 0.4252 | 0.2362 | 0.0235 | 0.0012 | 0.1173 | 0.0073 | 0.2179 | 0.0568 | 0.1485 | 0.1081 | 0.1623 | 0.1648 | 0.1467 | 0.2023 | 0.0826 | 0.1340 | 0.0615 | 0.1331 | 0.0396 | 0.1923 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0028 | 0.0018 | 0.0089 | 0.0066 | 0.0493 | 0.0407 | 0.0985 | 0.0784 | 0.0722 | 0.0592 | 0.0927 | 0.0831 | 0.6748 | 0.7298 | 0.0013 | 0.0008 | 0.0022 | 0.0025 | 0.0046 | 0.0081 | 0.0169 | 0.0211 | 0.0664 | 0.0802 | 0.1232 | 0.1307 | 0.0875 | 0.0958 | 0.1112 | 0.1158 | 0.5867 | 0.5449 | 0.0005 | 0.0023 | 0.0051 | 0.0144 | 0.0596 | 0.1114 | 0.0778 | 0.1061 | 0.6229 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 803 | 843 | | 8078 | 37469 | 422.2 | 79.09 | 159.69 | 223.20 | 327 | 354 | 375 | 397 | 417 | 437 | 459 | 489 | 531 | 0.0317 | 1189 | 1.189 | 110.68 | 36.67 | 1 | 0.0326 | 263 | 0.0007 | 56.32 | 7.529 | 0.1530 | 184520.0 | 83400000 | 38900000000 | 18700000000000 | 0.4100 | 0.2411 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0001 | 0.0130 | 0.0004 | 0.0471 | 0.0139 | 0.1043 | 0.0293 | 0.1147 | 0.0226 | 0.1480 | 0.0455 | 0.5695 | 0.8882 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0050 | 0.0000 | 0.0239 | 0.0107 | 0.0515 | 0.0209 | 0.0493 | 0.0112 | 0.0688 | 0.0227 | 0.8000 | 0.9344 | 0.0074 | 0.0206 | 0.0033 | 0.0155 | 0.0294 | 0.0722 | 0.0711 | 0.1598 | 0.1266 | 0.2268 | 0.1585 | 0.1701 | 0.1152 | 0.1495 | 0.1479 | 0.0979 | 0.3407 | 0.0876 | 0.0005 | 0.0054 | 0.0099 | 0.0311 | 0.0677 | 0.1022 | 0.1066 | 0.1196 | 0.5569 | 8 | 12 | 18 | 34 | 59 | 102 | 172 | 277 | 460 | 0.0551 | 26.43 | 5.339 | 0.4890 | 75319.8 | 53300000 | 47300000000 | 49000000000000 | 0.3610 | 0.2741 | 0.0647 | 0.0026 | 0.2087 | 0.0190 | 0.2734 | 0.1221 | 0.1568 | 0.1521 | 0.1237 | 0.2054 | 0.0877 | 0.1850 | 0.0465 | 0.1224 | 0.0270 | 0.0989 | 0.0115 | 0.0926 | 0.0006 | 0.0004 | 0.0007 | 0.0010 | 0.0031 | 0.0025 | 0.0146 | 0.0116 | 0.0594 | 0.0555 | 0.0986 | 0.0841 | 0.0693 | 0.0619 | 0.0969 | 0.0912 | 0.6568 | 0.6917 | 0.0009 | 0.0003 | 0.0015 | 0.0012 | 0.0039 | 0.0068 | 0.0169 | 0.0173 | 0.0767 | 0.0907 | 0.1116 | 0.1149 | 0.0824 | 0.0817 | 0.1129 | 0.1235 | 0.5932 | 0.5636 | 0.0006 | 0.0018 | 0.0039 | 0.0139 | 0.0709 | 0.1068 | 0.0718 | 0.1079 | 0.6224 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 591 | 322 | | 3805 | 8120 | 447.6 | 140.46 | 62.41 | 102.20 | 225 | 309 | 397 | 453 | 481 | 505 | 531 | 568 | 598 | 0.0792 | 643 | 1.179 | 95.75 | 35.78 | 2 | 0.0636 | 242 | 0.0012 | 24.22 | 7.023 | 0.2589 | 220069.0 | 114000000 | 61800000000 | 34400000000000 | 0.3868 | 0.2449 | 0.0017 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0114 | 0.0030 | 0.0542 | 0.0207 | 0.0787 | 0.0353 | 0.0685 | 0.0267 | 0.1038 | 0.0443 | 0.6805 | 0.8697 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0019 | 0.0183 | 0.0158 | 0.0254 | 0.0260 | 0.0183 | 0.0167 | 0.0268 | 0.0236 | 0.9097 | 0.9160 | 0.0009 | 0.0000 | 0.0037 | 0.0000 | 0.0083 | 0.0000 | 0.0111 | 0.0000 | 0.0426 | 0.0000 | 0.0546 | 0.0000 | 0.0592 | 0.0000 | 0.0823 | 0.0000 | 0.7373 | 1.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0047 | 0.0236 | 0.0356 | 0.0347 | 0.0592 | 0.8404 | 8 | 9 | 11 | 12 | 16 | 24 | 45 | 91 | 190 | 0.1789 | 5.12 | 3.242 | 0.6875 | 14337.8 | 5250000 | 2370000000 | 1220000000000 | 0.6067 | 0.0913 | 0.0581 | 0.0060 | 0.1183 | 0.0249 | 0.1618 | 0.0957 | 0.1390 | 0.1256 | 0.1784 | 0.1446 | 0.1515 | 0.1605 | 0.1224 | 0.1296 | 0.0456 | 0.0987 | 0.0249 | 0.2144 | 0.0017 | 0.0015 | 0.0035 | 0.0026 | 0.0035 | 0.0045 | 0.0138 | 0.0146 | 0.0558 | 0.0544 | 0.0878 | 0.0773 | 0.0636 | 0.0484 | 0.0930 | 0.0926 | 0.6775 | 0.7041 | 0.0005 | 0.0006 | 0.0005 | 0.0006 | 0.0033 | 0.0024 | 0.0169 | 0.0192 | 0.0754 | 0.0800 | 0.1038 | 0.1191 | 0.0644 | 0.0565 | 0.1032 | 0.1179 | 0.6319 | 0.6037 | 0.0010 | 0.0034 | 0.0039 | 0.0186 | 0.0658 | 0.0932 | 0.0677 | 0.0991 | 0.6472 |