High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1218 | 150 | | 8328 | 20825 | 278.7 | 60.80 | 290.87 | 439.80 | 204 | 240 | 258 | 272 | 285 | 298 | 311 | 327 | 347 | 0.0520 | 1082 | 0.814 | 131.22 | 25.94 | 2 | 0.0359 | 299 | 0.0015 | 25.68 | 6.861 | 0.2311 | 81369.2 | 24600000 | 7610000000 | 2410000000000 | 0.4056 | 0.2353 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0106 | 0.0006 | 0.0413 | 0.0112 | 0.0811 | 0.0241 | 0.0864 | 0.0135 | 0.1377 | 0.0258 | 0.6381 | 0.9247 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0001 | 0.0143 | 0.0100 | 0.0289 | 0.0185 | 0.0247 | 0.0084 | 0.0466 | 0.0146 | 0.8830 | 0.9483 | 0.0055 | 0.0364 | 0.0234 | 0.0182 | 0.0343 | 0.0455 | 0.0810 | 0.1273 | 0.1262 | 0.1364 | 0.1752 | 0.3091 | 0.1371 | 0.0909 | 0.1269 | 0.0727 | 0.2905 | 0.1636 | 0.0015 | 0.0033 | 0.0074 | 0.0220 | 0.0435 | 0.0863 | 0.0844 | 0.1177 | 0.6340 | 7 | 10 | 13 | 17 | 28 | 115 | 308 | 594 | 1020 | 0.0848 | 69.35 | 5.353 | 0.4886 | 278017.0 | 336000000 | 456000000000 | 669000000000000 | 0.5138 | 0.1645 | 0.0468 | 0.0052 | 0.1680 | 0.0170 | 0.2305 | 0.1168 | 0.1460 | 0.1394 | 0.1433 | 0.1748 | 0.1148 | 0.1667 | 0.0661 | 0.1295 | 0.0487 | 0.1130 | 0.0358 | 0.1375 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0009 | 0.0078 | 0.0073 | 0.0402 | 0.0330 | 0.0717 | 0.0659 | 0.0532 | 0.0476 | 0.0763 | 0.0708 | 0.7497 | 0.7740 | 0.0002 | 0.0011 | 0.0003 | 0.0020 | 0.0034 | 0.0050 | 0.0145 | 0.0131 | 0.0489 | 0.0487 | 0.0799 | 0.0830 | 0.0597 | 0.0625 | 0.0824 | 0.0882 | 0.7106 | 0.6963 | 0.0002 | 0.0002 | 0.0019 | 0.0108 | 0.0438 | 0.0821 | 0.0547 | 0.0780 | 0.7283 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1021 | 289 | | 15480 | 20962 | 107.9 | 32.54 | 126.87 | 115.24 | 70 | 80 | 88 | 96 | 104 | 112 | 122 | 133 | 151 | 0.0665 | 1394 | 1.246 | 41.87 | 18.36 | 4 | 0.0075 | 116 | 0.0011 | 32.98 | 7.115 | 0.2122 | 12708.7 | 1630000 | 225000000 | 33600000000 | 0.4430 | 0.2071 | 0.0021 | 0.0002 | 0.0042 | 0.0005 | 0.0146 | 0.0012 | 0.0424 | 0.0071 | 0.1092 | 0.0273 | 0.1709 | 0.0639 | 0.1595 | 0.0673 | 0.1788 | 0.1076 | 0.3183 | 0.7248 | 0.0014 | 0.0002 | 0.0020 | 0.0003 | 0.0039 | 0.0009 | 0.0118 | 0.0037 | 0.0393 | 0.0149 | 0.0650 | 0.0333 | 0.0601 | 0.0290 | 0.0876 | 0.0504 | 0.7289 | 0.8672 | 0.0025 | 0.0080 | 0.0037 | 0.0173 | 0.0202 | 0.0306 | 0.0567 | 0.0766 | 0.1110 | 0.1671 | 0.1514 | 0.1598 | 0.1194 | 0.1152 | 0.1455 | 0.1418 | 0.3896 | 0.2836 | 0.0011 | 0.0021 | 0.0090 | 0.0274 | 0.0627 | 0.1065 | 0.0944 | 0.1225 | 0.5742 | 16 | 27 | 45 | 67 | 94 | 124 | 161 | 212 | 289 | 0.0159 | 8.96 | 5.332 | 0.5036 | 29376.6 | 9390000 | 3750000000 | 1790000000000 | 0.4948 | 0.1572 | 0.0112 | 0.0016 | 0.0613 | 0.0068 | 0.1433 | 0.0245 | 0.1682 | 0.0618 | 0.1919 | 0.1370 | 0.1645 | 0.1771 | 0.1051 | 0.1416 | 0.0836 | 0.1568 | 0.0709 | 0.2928 | 0.0008 | 0.0004 | 0.0011 | 0.0016 | 0.0035 | 0.0026 | 0.0133 | 0.0076 | 0.0489 | 0.0371 | 0.0788 | 0.0577 | 0.0640 | 0.0520 | 0.0930 | 0.0767 | 0.6966 | 0.7643 | 0.0006 | 0.0013 | 0.0028 | 0.0020 | 0.0070 | 0.0071 | 0.0249 | 0.0329 | 0.0705 | 0.0821 | 0.1139 | 0.1305 | 0.0891 | 0.1028 | 0.1163 | 0.1349 | 0.5748 | 0.5065 | 0.0001 | 0.0018 | 0.0055 | 0.0186 | 0.0602 | 0.0898 | 0.0819 | 0.1099 | 0.6321 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 537 | 652 | | 760 | 4733 | 183.3 | 48.14 | 141.14 | 250.71 | 130 | 142 | 153 | 163 | 173 | 188 | 202 | 222 | 250 | 0.1054 | 499 | 0.979 | 146.17 | 42.01 | 2 | 0.4618 | 351 | 0.0030 | 36.55 | 6.002 | 0.2222 | 35909.5 | 7530000 | 1680000000 | 400000000000 | 0.4861 | 0.1592 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0652 | 0.0044 | 0.0966 | 0.0175 | 0.1473 | 0.0773 | 0.1546 | 0.0962 | 0.1812 | 0.0845 | 0.1594 | 0.0962 | 0.1860 | 0.6239 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0297 | 0.0054 | 0.0822 | 0.0549 | 0.1154 | 0.0776 | 0.1136 | 0.0415 | 0.1416 | 0.0776 | 0.5105 | 0.7430 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0253 | 0.0328 | 0.0823 | 0.2131 | 0.2595 | 0.2295 | 0.1329 | 0.2131 | 0.1139 | 0.0984 | 0.1835 | 0.1311 | 0.1962 | 0.0820 | 0.0000 | 0.0000 | 0.0150 | 0.0300 | 0.1502 | 0.1922 | 0.0991 | 0.1381 | 0.3754 | 7 | 8 | 10 | 12 | 18 | 39 | 88 | 210 | 496 | 0.1437 | 25.58 | 4.029 | 0.5929 | 82762.0 | 66600000 | 60800000000 | 59600000000000 | 0.6762 | 0.0517 | 0.0645 | 0.0022 | 0.2719 | 0.0410 | 0.3548 | 0.1339 | 0.1475 | 0.2009 | 0.0876 | 0.2203 | 0.0553 | 0.1749 | 0.0138 | 0.1058 | 0.0046 | 0.0756 | 0.0000 | 0.0454 | 0.0008 | 0.0000 | 0.0000 | 0.0007 | 0.0008 | 0.0007 | 0.0094 | 0.0131 | 0.0602 | 0.0518 | 0.1063 | 0.0801 | 0.0493 | 0.0608 | 0.1009 | 0.0849 | 0.6724 | 0.7079 | 0.0000 | 0.0000 | 0.0019 | 0.0020 | 0.0028 | 0.0020 | 0.0104 | 0.0132 | 0.0669 | 0.0731 | 0.1121 | 0.1015 | 0.0574 | 0.0701 | 0.0989 | 0.1036 | 0.6497 | 0.6345 | 0.0000 | 0.0000 | 0.0034 | 0.0086 | 0.0738 | 0.0935 | 0.0626 | 0.0995 | 0.6587 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 959 | 713 | | 6139 | 10848 | 256.2 | 53.54 | 207.18 | 194.13 | 190 | 210 | 225 | 238 | 252 | 266 | 283 | 302 | 326 | 0.0678 | 736 | 1.177 | 102.18 | 37.66 | 1 | 0.0415 | 255 | 0.0008 | 47.93 | 7.299 | 0.1591 | 68517.0 | 19100000 | 5540000000 | 1670000000000 | 0.4834 | 0.1799 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0032 | 0.0003 | 0.0156 | 0.0014 | 0.0740 | 0.0133 | 0.1454 | 0.0377 | 0.1504 | 0.0343 | 0.1835 | 0.0591 | 0.4267 | 0.8538 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0002 | 0.0059 | 0.0012 | 0.0355 | 0.0092 | 0.0646 | 0.0250 | 0.0616 | 0.0171 | 0.0826 | 0.0290 | 0.7478 | 0.9183 | 0.0067 | 0.0235 | 0.0114 | 0.0141 | 0.0352 | 0.0469 | 0.0856 | 0.1643 | 0.1369 | 0.1925 | 0.1835 | 0.2207 | 0.1274 | 0.0845 | 0.1340 | 0.0986 | 0.2795 | 0.1549 | 0.0024 | 0.0041 | 0.0093 | 0.0368 | 0.0764 | 0.1195 | 0.1012 | 0.1326 | 0.5176 | 19 | 34 | 61 | 103 | 155 | 210 | 274 | 353 | 472 | 0.0078 | 34.55 | 6.449 | 0.3311 | 80606.7 | 42400000 | 27300000000 | 20400000000000 | 0.4122 | 0.2269 | 0.0375 | 0.0010 | 0.1827 | 0.0076 | 0.2438 | 0.0851 | 0.1774 | 0.1506 | 0.1360 | 0.1962 | 0.1064 | 0.2035 | 0.0572 | 0.1157 | 0.0420 | 0.0994 | 0.0171 | 0.1407 | 0.0008 | 0.0002 | 0.0010 | 0.0012 | 0.0031 | 0.0027 | 0.0179 | 0.0119 | 0.0702 | 0.0586 | 0.1159 | 0.1040 | 0.0844 | 0.0695 | 0.1125 | 0.0949 | 0.5943 | 0.6571 | 0.0016 | 0.0020 | 0.0038 | 0.0020 | 0.0071 | 0.0076 | 0.0245 | 0.0311 | 0.0919 | 0.0967 | 0.1321 | 0.1652 | 0.1025 | 0.1119 | 0.1394 | 0.1317 | 0.4971 | 0.4518 | 0.0016 | 0.0016 | 0.0043 | 0.0200 | 0.0832 | 0.1402 | 0.0836 | 0.1216 | 0.5440 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 367 | 527 | | 14166 | 30978 | 166.3 | 51.48 | 150.74 | 180.13 | 108 | 123 | 136 | 147 | 158 | 171 | 186 | 207 | 241 | 0.0455 | 1410 | 1.186 | 107.56 | 39.85 | 4 | 0.0193 | 274 | 0.0029 | 11.78 | 6.212 | 0.3232 | 30318.4 | 6020000 | 1290000000 | 298000000000 | 0.4567 | 0.2012 | 0.0010 | 0.0002 | 0.0020 | 0.0003 | 0.0095 | 0.0011 | 0.0293 | 0.0063 | 0.0939 | 0.0301 | 0.1627 | 0.0648 | 0.1523 | 0.0591 | 0.1747 | 0.0901 | 0.3747 | 0.7480 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0027 | 0.0002 | 0.0099 | 0.0021 | 0.0378 | 0.0155 | 0.0638 | 0.0296 | 0.0626 | 0.0267 | 0.0911 | 0.0439 | 0.7313 | 0.8820 | 0.0021 | 0.0018 | 0.0049 | 0.0083 | 0.0147 | 0.0155 | 0.0350 | 0.0596 | 0.0936 | 0.1173 | 0.1393 | 0.1757 | 0.0967 | 0.1203 | 0.1362 | 0.1471 | 0.4774 | 0.3544 | 0.0008 | 0.0034 | 0.0088 | 0.0319 | 0.0709 | 0.1074 | 0.0856 | 0.1046 | 0.5866 | 8 | 10 | 15 | 33 | 75 | 129 | 195 | 283 | 413 | 0.0651 | 14.33 | 5.012 | 0.4997 | 55169.9 | 27400000 | 16300000000 | 11100000000000 | 0.5068 | 0.1638 | 0.0376 | 0.0026 | 0.1800 | 0.0101 | 0.2471 | 0.0930 | 0.1592 | 0.1413 | 0.1404 | 0.1940 | 0.1108 | 0.1938 | 0.0625 | 0.1310 | 0.0393 | 0.1131 | 0.0232 | 0.1211 | 0.0002 | 0.0002 | 0.0005 | 0.0001 | 0.0016 | 0.0012 | 0.0097 | 0.0069 | 0.0522 | 0.0426 | 0.0886 | 0.0730 | 0.0686 | 0.0557 | 0.1054 | 0.0879 | 0.6732 | 0.7326 | 0.0004 | 0.0006 | 0.0015 | 0.0020 | 0.0027 | 0.0051 | 0.0177 | 0.0220 | 0.0740 | 0.0904 | 0.1206 | 0.1278 | 0.0882 | 0.0952 | 0.1271 | 0.1330 | 0.5678 | 0.5239 | 0.0000 | 0.0020 | 0.0028 | 0.0144 | 0.0620 | 0.1077 | 0.0815 | 0.1152 | 0.6146 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 202 | 300 | | 6785 | 14162 | 73.6 | 17.99 | 128.75 | 204.22 | 55 | 60 | 64 | 67 | 70 | 74 | 78 | 85 | 98 | 0.0703 | 996 | 0.964 | 72.80 | 24.35 | 1 | 0.0280 | 190 | 0.0034 | 16.24 | 6.105 | 0.2850 | 5739.9 | 477688 | 42700000 | 4120000000 | 0.4408 | 0.2110 | 0.0005 | 0.0000 | 0.0039 | 0.0005 | 0.0122 | 0.0021 | 0.0270 | 0.0047 | 0.0766 | 0.0226 | 0.1354 | 0.0389 | 0.1541 | 0.0501 | 0.2125 | 0.0784 | 0.3779 | 0.8028 | 0.0002 | 0.0000 | 0.0015 | 0.0001 | 0.0044 | 0.0000 | 0.0115 | 0.0003 | 0.0412 | 0.0127 | 0.0738 | 0.0228 | 0.0842 | 0.0195 | 0.1337 | 0.0408 | 0.6495 | 0.9038 | 0.0089 | 0.0082 | 0.0124 | 0.0392 | 0.0231 | 0.0351 | 0.0738 | 0.1072 | 0.1120 | 0.1691 | 0.1431 | 0.1794 | 0.1182 | 0.1381 | 0.1476 | 0.1196 | 0.3609 | 0.2041 | 0.0051 | 0.0116 | 0.0260 | 0.0619 | 0.0952 | 0.1284 | 0.1208 | 0.1302 | 0.4208 | 12 | 14 | 16 | 19 | 29 | 64 | 131 | 219 | 365 | 0.0796 | 32.45 | 4.690 | 0.5502 | 58277.5 | 46900000 | 56200000000 | 88300000000000 | 0.5837 | 0.1324 | 0.0408 | 0.0021 | 0.1841 | 0.0191 | 0.2326 | 0.0908 | 0.1830 | 0.1300 | 0.1709 | 0.1990 | 0.1158 | 0.1879 | 0.0364 | 0.1423 | 0.0254 | 0.1147 | 0.0110 | 0.1141 | 0.0008 | 0.0004 | 0.0008 | 0.0017 | 0.0017 | 0.0017 | 0.0080 | 0.0075 | 0.0431 | 0.0368 | 0.0772 | 0.0632 | 0.0574 | 0.0462 | 0.1056 | 0.0896 | 0.7054 | 0.7529 | 0.0008 | 0.0006 | 0.0008 | 0.0020 | 0.0029 | 0.0050 | 0.0130 | 0.0190 | 0.0619 | 0.0781 | 0.1060 | 0.1085 | 0.0824 | 0.0930 | 0.1331 | 0.1355 | 0.5993 | 0.5582 | 0.0000 | 0.0009 | 0.0016 | 0.0108 | 0.0498 | 0.0912 | 0.0683 | 0.1170 | 0.6604 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 902 | 486 | | 1571 | 8752 | 79.8 | 18.38 | 25.85 | 63.61 | 59 | 62 | 66 | 70 | 75 | 84 | 92 | 99 | 106 | 0.0978 | 856 | 0.759 | 104.01 | 24.21 | 3 | 0.1827 | 287 | 0.0137 | 2.82 | 4.627 | 0.5218 | 6709.4 | 592170 | 54600000 | 5230000000 | 0.4037 | 0.2309 | 0.0050 | 0.0000 | 0.0099 | 0.0000 | 0.0236 | 0.0000 | 0.0459 | 0.0067 | 0.0980 | 0.0299 | 0.1613 | 0.0552 | 0.1365 | 0.0579 | 0.1675 | 0.0685 | 0.3524 | 0.7818 | 0.0033 | 0.0000 | 0.0033 | 0.0000 | 0.0117 | 0.0000 | 0.0208 | 0.0045 | 0.0400 | 0.0248 | 0.0650 | 0.0446 | 0.0550 | 0.0299 | 0.0708 | 0.0350 | 0.7300 | 0.8611 | 0.0000 | 0.0299 | 0.0000 | 0.0746 | 0.0203 | 0.0597 | 0.0330 | 0.1642 | 0.0787 | 0.1045 | 0.1320 | 0.1493 | 0.1142 | 0.0746 | 0.1345 | 0.1194 | 0.4873 | 0.2239 | 0.0000 | 0.0057 | 0.0057 | 0.0213 | 0.0355 | 0.0682 | 0.0540 | 0.0753 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 12 | 53 | 0.2949 | 7.14 | 2.200 | 0.6924 | 4714.0 | 1480000 | 590000000 | 281000000000 | 0.4076 | 0.1755 | 0.0603 | 0.0111 | 0.2915 | 0.0379 | 0.4824 | 0.1737 | 0.1407 | 0.2517 | 0.0101 | 0.2539 | 0.0101 | 0.1403 | 0.0050 | 0.0802 | 0.0000 | 0.0379 | 0.0000 | 0.0134 | 0.0008 | 0.0035 | 0.0041 | 0.0077 | 0.0154 | 0.0153 | 0.0170 | 0.0251 | 0.0519 | 0.0537 | 0.0787 | 0.0760 | 0.0463 | 0.0530 | 0.0779 | 0.0746 | 0.7078 | 0.6911 | 0.0019 | 0.0030 | 0.0039 | 0.0020 | 0.0048 | 0.0030 | 0.0087 | 0.0071 | 0.0571 | 0.0569 | 0.0871 | 0.0944 | 0.0600 | 0.0650 | 0.0794 | 0.0792 | 0.6970 | 0.6893 | 0.0018 | 0.0090 | 0.0045 | 0.0170 | 0.0502 | 0.0806 | 0.0556 | 0.0762 | 0.7052 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 996 | 371 | | 11089 | 20661 | 128.1 | 44.85 | 133.68 | 162.62 | 71 | 85 | 99 | 115 | 127 | 138 | 151 | 166 | 188 | 0.0798 | 1648 | 0.895 | 64.56 | 20.03 | 5 | 0.0157 | 174 | 0.0018 | 12.86 | 6.621 | 0.3191 | 18415.0 | 2900000 | 491000000 | 88000000000 | 0.4803 | 0.1576 | 0.0011 | 0.0006 | 0.0045 | 0.0016 | 0.0117 | 0.0035 | 0.0293 | 0.0084 | 0.0819 | 0.0379 | 0.1359 | 0.0583 | 0.1247 | 0.0644 | 0.1531 | 0.0930 | 0.4578 | 0.7323 | 0.0005 | 0.0003 | 0.0015 | 0.0006 | 0.0021 | 0.0017 | 0.0042 | 0.0037 | 0.0222 | 0.0194 | 0.0351 | 0.0255 | 0.0297 | 0.0272 | 0.0482 | 0.0398 | 0.8566 | 0.8816 | 0.0019 | 0.0046 | 0.0038 | 0.0046 | 0.0118 | 0.0178 | 0.0290 | 0.0462 | 0.0667 | 0.1116 | 0.1062 | 0.1155 | 0.0871 | 0.1063 | 0.1161 | 0.1373 | 0.5774 | 0.4561 | 0.0020 | 0.0040 | 0.0047 | 0.0125 | 0.0360 | 0.0599 | 0.0579 | 0.0894 | 0.7335 | 14 | 19 | 29 | 48 | 73 | 107 | 151 | 215 | 335 | 0.0199 | 22.80 | 5.542 | 0.4729 | 44312.1 | 23700000 | 16900000000 | 14500000000000 | 0.5483 | 0.1240 | 0.0154 | 0.0018 | 0.0718 | 0.0095 | 0.1644 | 0.0294 | 0.1714 | 0.0676 | 0.1731 | 0.1375 | 0.1619 | 0.1889 | 0.0967 | 0.1393 | 0.0751 | 0.1444 | 0.0702 | 0.2815 | 0.0008 | 0.0004 | 0.0017 | 0.0019 | 0.0035 | 0.0031 | 0.0174 | 0.0115 | 0.0505 | 0.0433 | 0.0835 | 0.0717 | 0.0604 | 0.0502 | 0.0852 | 0.0807 | 0.6968 | 0.7370 | 0.0015 | 0.0010 | 0.0051 | 0.0020 | 0.0056 | 0.0073 | 0.0197 | 0.0275 | 0.0672 | 0.0761 | 0.1032 | 0.1073 | 0.0716 | 0.0804 | 0.1082 | 0.1177 | 0.6178 | 0.5806 | 0.0010 | 0.0039 | 0.0055 | 0.0211 | 0.0524 | 0.0978 | 0.0670 | 0.0986 | 0.6527 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 961 | 737 | | 4967 | 9103 | 329.4 | 79.77 | 74.56 | 85.94 | 235 | 262 | 283 | 302 | 321 | 340 | 364 | 392 | 439 | 0.0955 | 869 | 1.203 | 114.14 | 50.48 | 1 | 0.0632 | 314 | 0.0010 | 41.76 | 7.101 | 0.1685 | 114878.0 | 42400000 | 16500000000 | 6770000000000 | 0.4275 | 0.2253 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0080 | 0.0002 | 0.0251 | 0.0024 | 0.0931 | 0.0218 | 0.1507 | 0.0517 | 0.1563 | 0.0579 | 0.1845 | 0.0764 | 0.3813 | 0.7896 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0000 | 0.0076 | 0.0006 | 0.0416 | 0.0124 | 0.0718 | 0.0304 | 0.0680 | 0.0240 | 0.1070 | 0.0391 | 0.7025 | 0.8934 | 0.0052 | 0.0061 | 0.0000 | 0.0122 | 0.0241 | 0.0396 | 0.0680 | 0.1250 | 0.1339 | 0.1860 | 0.1695 | 0.1799 | 0.1056 | 0.1128 | 0.1538 | 0.1463 | 0.3400 | 0.1921 | 0.0013 | 0.0013 | 0.0083 | 0.0420 | 0.0918 | 0.1263 | 0.0997 | 0.1228 | 0.5066 | 6 | 8 | 13 | 22 | 41 | 63 | 93 | 132 | 194 | 0.0625 | 5.33 | 4.498 | 0.5801 | 12944.9 | 3140000 | 911000000 | 296000000000 | 0.5225 | 0.1439 | 0.0229 | 0.0000 | 0.1064 | 0.0109 | 0.2273 | 0.0510 | 0.1804 | 0.1108 | 0.1752 | 0.1639 | 0.1470 | 0.1821 | 0.0792 | 0.1561 | 0.0396 | 0.1452 | 0.0219 | 0.1800 | 0.0000 | 0.0000 | 0.0005 | 0.0016 | 0.0008 | 0.0023 | 0.0124 | 0.0105 | 0.0463 | 0.0407 | 0.0816 | 0.0537 | 0.0624 | 0.0553 | 0.0945 | 0.0834 | 0.7015 | 0.7524 | 0.0000 | 0.0008 | 0.0014 | 0.0020 | 0.0056 | 0.0061 | 0.0190 | 0.0228 | 0.0669 | 0.0759 | 0.1025 | 0.1113 | 0.0817 | 0.0893 | 0.1141 | 0.1199 | 0.6088 | 0.5718 | 0.0009 | 0.0006 | 0.0019 | 0.0126 | 0.0638 | 0.0854 | 0.0780 | 0.1043 | 0.6524 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 305 | 753 | | 14531 | 31502 | 446.4 | 61.03 | 117.13 | 162.48 | 365 | 402 | 424 | 439 | 452 | 464 | 476 | 491 | 515 | 0.0488 | 1538 | 0.844 | 110.02 | 27.80 | 4 | 0.0189 | 274 | 0.0017 | 18.96 | 6.823 | 0.2707 | 202963.0 | 93800000 | 44000000000 | 21000000000000 | 0.4307 | 0.2135 | 0.0003 | 0.0001 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0036 | 0.0001 | 0.0149 | 0.0077 | 0.0284 | 0.0166 | 0.0253 | 0.0080 | 0.0383 | 0.0128 | 0.8882 | 0.9547 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0001 | 0.0098 | 0.0077 | 0.0186 | 0.0166 | 0.0149 | 0.0080 | 0.0188 | 0.0117 | 0.9360 | 0.9558 | 0.0148 | 1.0000 | 0.0239 | 0.0000 | 0.0091 | 0.0000 | 0.0262 | 0.0000 | 0.0809 | 0.0000 | 0.0945 | 0.0000 | 0.0809 | 0.0000 | 0.1173 | 0.0000 | 0.5524 | 0.0000 | 0.0022 | 0.0070 | 0.0123 | 0.0187 | 0.0346 | 0.0523 | 0.0642 | 0.0921 | 0.7167 | 13 | 16 | 21 | 33 | 52 | 79 | 118 | 180 | 305 | 0.0400 | 19.55 | 4.937 | 0.5597 | 40119.5 | 22800000 | 16800000000 | 14600000000000 | 0.4801 | 0.1897 | 0.0180 | 0.0019 | 0.0684 | 0.0102 | 0.1417 | 0.0304 | 0.1389 | 0.0605 | 0.1660 | 0.1385 | 0.1648 | 0.1775 | 0.1107 | 0.1263 | 0.1041 | 0.1394 | 0.0873 | 0.3154 | 0.0012 | 0.0003 | 0.0022 | 0.0020 | 0.0034 | 0.0030 | 0.0115 | 0.0124 | 0.0463 | 0.0387 | 0.0745 | 0.0614 | 0.0495 | 0.0472 | 0.0766 | 0.0656 | 0.7348 | 0.7694 | 0.0005 | 0.0007 | 0.0024 | 0.0020 | 0.0066 | 0.0068 | 0.0187 | 0.0217 | 0.0585 | 0.0622 | 0.0953 | 0.1084 | 0.0633 | 0.0699 | 0.0954 | 0.0979 | 0.6595 | 0.6304 | 0.0004 | 0.0017 | 0.0044 | 0.0151 | 0.0498 | 0.0888 | 0.0599 | 0.0831 | 0.6968 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 489 | 834 | | 12111 | 18609 | 541.6 | 118.52 | 168.67 | 182.80 | 399 | 441 | 476 | 505 | 532 | 559 | 589 | 628 | 690 | 0.0564 | 1049 | 1.226 | 127.68 | 55.00 | 1 | 0.0283 | 343 | 0.0010 | 25.57 | 7.191 | 0.2311 | 307350.0 | 183000000 | 114000000000 | 74500000000000 | 0.4223 | 0.2210 | 0.0002 | 0.0001 | 0.0011 | 0.0003 | 0.0035 | 0.0002 | 0.0121 | 0.0018 | 0.0351 | 0.0123 | 0.0639 | 0.0223 | 0.0770 | 0.0188 | 0.1064 | 0.0282 | 0.7006 | 0.9161 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0017 | 0.0002 | 0.0050 | 0.0010 | 0.0150 | 0.0084 | 0.0268 | 0.0140 | 0.0306 | 0.0093 | 0.0434 | 0.0135 | 0.8767 | 0.9536 | 0.0032 | 0.0045 | 0.0053 | 0.0061 | 0.0150 | 0.0151 | 0.0513 | 0.0363 | 0.0898 | 0.0802 | 0.1165 | 0.1104 | 0.1010 | 0.0726 | 0.1112 | 0.1104 | 0.5067 | 0.5643 | 0.0016 | 0.0023 | 0.0060 | 0.0213 | 0.0499 | 0.0789 | 0.0809 | 0.1040 | 0.6550 | 8 | 14 | 27 | 56 | 102 | 159 | 227 | 312 | 435 | 0.0253 | 65.01 | 6.264 | 0.3576 | 61863.3 | 30100000 | 17400000000 | 11500000000000 | 0.4777 | 0.1891 | 0.0835 | 0.0023 | 0.2306 | 0.0249 | 0.2838 | 0.1678 | 0.1513 | 0.1698 | 0.1153 | 0.1751 | 0.0782 | 0.1769 | 0.0402 | 0.1114 | 0.0146 | 0.0964 | 0.0026 | 0.0755 | 0.0004 | 0.0001 | 0.0000 | 0.0000 | 0.0005 | 0.0009 | 0.0147 | 0.0085 | 0.0655 | 0.0544 | 0.1197 | 0.0976 | 0.0848 | 0.0670 | 0.1186 | 0.1038 | 0.5959 | 0.6678 | 0.0000 | 0.0007 | 0.0011 | 0.0021 | 0.0057 | 0.0062 | 0.0239 | 0.0327 | 0.0959 | 0.1092 | 0.1534 | 0.1697 | 0.1026 | 0.1133 | 0.1390 | 0.1561 | 0.4782 | 0.4101 | 0.0001 | 0.0000 | 0.0024 | 0.0177 | 0.0832 | 0.1361 | 0.0944 | 0.1341 | 0.5320 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 318 | 398 | | 21149 | 32393 | 118.4 | 36.13 | 198.09 | 230.96 | 79 | 89 | 97 | 105 | 112 | 121 | 131 | 144 | 166 | 0.0593 | 1920 | 0.736 | 173.25 | 37.64 | 3 | 0.0214 | 452 | 0.0021 | 20.81 | 6.559 | 0.2661 | 15334.3 | 2180000 | 343000000 | 59700000000 | 0.4453 | 0.2046 | 0.0012 | 0.0001 | 0.0027 | 0.0003 | 0.0109 | 0.0011 | 0.0349 | 0.0049 | 0.1040 | 0.0257 | 0.1712 | 0.0574 | 0.1644 | 0.0633 | 0.1813 | 0.0975 | 0.3295 | 0.7498 | 0.0006 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0008 | 0.0116 | 0.0021 | 0.0381 | 0.0130 | 0.0636 | 0.0258 | 0.0677 | 0.0265 | 0.0964 | 0.0418 | 0.7166 | 0.8899 | 0.0030 | 0.0065 | 0.0063 | 0.0145 | 0.0203 | 0.0187 | 0.0586 | 0.0816 | 0.1155 | 0.1493 | 0.1471 | 0.1968 | 0.1274 | 0.1129 | 0.1298 | 0.1399 | 0.3918 | 0.2799 | 0.0020 | 0.0048 | 0.0084 | 0.0315 | 0.0770 | 0.1122 | 0.0985 | 0.1278 | 0.5378 | 14 | 17 | 25 | 48 | 96 | 167 | 259 | 373 | 535 | 0.0276 | 93.42 | 6.409 | 0.3746 | 92580.9 | 58500000 | 44100000000 | 37800000000000 | 0.5719 | 0.1057 | 0.0647 | 0.0020 | 0.2147 | 0.0220 | 0.2542 | 0.1155 | 0.1479 | 0.1648 | 0.1256 | 0.1968 | 0.0936 | 0.1670 | 0.0523 | 0.1282 | 0.0303 | 0.0948 | 0.0169 | 0.1089 | 0.0004 | 0.0002 | 0.0013 | 0.0011 | 0.0026 | 0.0022 | 0.0119 | 0.0095 | 0.0574 | 0.0487 | 0.0985 | 0.0827 | 0.0773 | 0.0653 | 0.1116 | 0.0939 | 0.6390 | 0.6965 | 0.0004 | 0.0003 | 0.0016 | 0.0021 | 0.0053 | 0.0067 | 0.0183 | 0.0246 | 0.0756 | 0.0872 | 0.1236 | 0.1318 | 0.0932 | 0.1017 | 0.1281 | 0.1345 | 0.5539 | 0.5111 | 0.0007 | 0.0017 | 0.0031 | 0.0149 | 0.0664 | 0.1128 | 0.0859 | 0.1198 | 0.5947 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 445 | 860 | | 2608 | 8307 | 566.5 | 225.38 | 39.43 | 65.37 | 258 | 310 | 392 | 503 | 596 | 677 | 750 | 806 | 842 | 0.0768 | 638 | 0.880 | 77.20 | 20.00 | 3 | 0.0740 | 193 | 0.0009 | 51.94 | 7.257 | 0.1702 | 371659.0 | 266000000 | 199000000000 | 154000000000000 | 0.3620 | 0.2536 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0062 | 0.0029 | 0.0123 | 0.0065 | 0.1200 | 0.0632 | 0.2369 | 0.1142 | 0.1323 | 0.0639 | 0.1477 | 0.1128 | 0.3446 | 0.6358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0012 | 0.0010 | 0.0244 | 0.0282 | 0.0463 | 0.0423 | 0.0220 | 0.0216 | 0.0404 | 0.0423 | 0.8657 | 0.8636 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0010 | 0.0034 | 0.0077 | 0.0151 | 0.0349 | 0.0689 | 0.0668 | 0.1109 | 0.0445 | 0.0723 | 0.0649 | 0.1008 | 0.7803 | 0.6269 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0351 | 0.0537 | 0.0387 | 0.0530 | 0.8173 | 7 | 8 | 10 | 12 | 14 | 19 | 25 | 43 | 117 | 0.0947 | 6.43 | 3.634 | 0.6797 | 5827.2 | 1490000 | 484000000 | 182000000000 | 0.3887 | 0.2572 | 0.0457 | 0.0156 | 0.1087 | 0.0288 | 0.1130 | 0.0600 | 0.1478 | 0.1019 | 0.1870 | 0.1397 | 0.1565 | 0.1265 | 0.1326 | 0.1167 | 0.0913 | 0.1553 | 0.0174 | 0.2555 | 0.0059 | 0.0065 | 0.0054 | 0.0126 | 0.0049 | 0.0153 | 0.0178 | 0.0252 | 0.0425 | 0.0520 | 0.0623 | 0.0566 | 0.0440 | 0.0539 | 0.0667 | 0.0768 | 0.7505 | 0.7012 | 0.0019 | 0.0007 | 0.0051 | 0.0021 | 0.0064 | 0.0064 | 0.0230 | 0.0207 | 0.0499 | 0.0486 | 0.0671 | 0.0671 | 0.0486 | 0.0471 | 0.0633 | 0.0643 | 0.7347 | 0.7429 | 0.0011 | 0.0011 | 0.0034 | 0.0190 | 0.0514 | 0.0587 | 0.0509 | 0.0799 | 0.7345 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 854 | 856 | | 7221 | 14570 | 49.4 | 17.53 | 78.00 | 136.28 | 28 | 34 | 38 | 43 | 47 | 52 | 58 | 64 | 73 | 0.0925 | 1347 | 0.564 | 226.82 | 39.32 | 13 | 0.0867 | 626 | 0.0060 | 6.82 | 5.419 | 0.3768 | 2746.4 | 169000 | 11300000 | 819000000 | 0.4385 | 0.1979 | 0.0021 | 0.0002 | 0.0092 | 0.0013 | 0.0509 | 0.0036 | 0.1206 | 0.0209 | 0.1835 | 0.0519 | 0.1998 | 0.1171 | 0.1729 | 0.1192 | 0.1266 | 0.1517 | 0.1344 | 0.5342 | 0.0004 | 0.0000 | 0.0012 | 0.0005 | 0.0037 | 0.0013 | 0.0217 | 0.0112 | 0.0562 | 0.0266 | 0.0864 | 0.0540 | 0.0848 | 0.0579 | 0.1085 | 0.0691 | 0.6371 | 0.7796 | 0.0039 | 0.0097 | 0.0073 | 0.0154 | 0.0194 | 0.0328 | 0.0682 | 0.0936 | 0.1094 | 0.1380 | 0.1510 | 0.1979 | 0.1292 | 0.1342 | 0.1549 | 0.1467 | 0.3567 | 0.2317 | 0.0017 | 0.0026 | 0.0125 | 0.0408 | 0.0755 | 0.1098 | 0.1078 | 0.1329 | 0.5163 | 11 | 13 | 15 | 17 | 20 | 26 | 46 | 104 | 234 | 0.1860 | 10.58 | 3.510 | 0.6862 | 24655.2 | 13200000 | 8940000000 | 7000000000000 | 0.6410 | 0.1101 | 0.1548 | 0.0039 | 0.3289 | 0.0394 | 0.2946 | 0.2229 | 0.1131 | 0.2327 | 0.0565 | 0.2189 | 0.0298 | 0.1433 | 0.0134 | 0.0671 | 0.0074 | 0.0493 | 0.0015 | 0.0224 | 0.0008 | 0.0002 | 0.0008 | 0.0005 | 0.0032 | 0.0053 | 0.0201 | 0.0138 | 0.0823 | 0.0766 | 0.1173 | 0.0994 | 0.0839 | 0.0713 | 0.1284 | 0.1266 | 0.5631 | 0.6063 | 0.0003 | 0.0007 | 0.0023 | 0.0021 | 0.0058 | 0.0053 | 0.0229 | 0.0248 | 0.1011 | 0.1076 | 0.1308 | 0.1522 | 0.0995 | 0.0995 | 0.1485 | 0.1501 | 0.4889 | 0.4577 | 0.0000 | 0.0023 | 0.0053 | 0.0197 | 0.0978 | 0.1169 | 0.0934 | 0.1436 | 0.5211 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 370 | 294 | | 5485 | 10563 | 124.0 | 34.56 | 117.76 | 103.27 | 86 | 95 | 103 | 110 | 117 | 126 | 136 | 150 | 170 | 0.0846 | 894 | 0.963 | 95.52 | 33.42 | 1 | 0.0500 | 274 | 0.0022 | 24.84 | 6.477 | 0.2498 | 16564.2 | 2390000 | 374000000 | 63000000000 | 0.4073 | 0.2446 | 0.0010 | 0.0000 | 0.0044 | 0.0000 | 0.0153 | 0.0012 | 0.0435 | 0.0059 | 0.1084 | 0.0244 | 0.1855 | 0.0590 | 0.1804 | 0.0658 | 0.1696 | 0.1047 | 0.2919 | 0.7390 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0066 | 0.0000 | 0.0172 | 0.0021 | 0.0434 | 0.0153 | 0.0767 | 0.0283 | 0.0797 | 0.0280 | 0.0995 | 0.0527 | 0.6749 | 0.8736 | 0.0026 | 0.0083 | 0.0097 | 0.0145 | 0.0150 | 0.0455 | 0.0607 | 0.1074 | 0.1514 | 0.1653 | 0.1752 | 0.2045 | 0.1294 | 0.1157 | 0.1488 | 0.1322 | 0.3072 | 0.2066 | 0.0026 | 0.0047 | 0.0129 | 0.0331 | 0.0786 | 0.1301 | 0.1108 | 0.1447 | 0.4826 | 16 | 26 | 41 | 63 | 88 | 117 | 152 | 200 | 268 | 0.0059 | 25.56 | 6.335 | 0.3474 | 24530.7 | 6760000 | 2220000000 | 822000000000 | 0.5829 | 0.1325 | 0.0182 | 0.0019 | 0.0846 | 0.0051 | 0.1973 | 0.0296 | 0.1849 | 0.0819 | 0.1784 | 0.1674 | 0.1426 | 0.2027 | 0.0990 | 0.1609 | 0.0736 | 0.1539 | 0.0215 | 0.1966 | 0.0002 | 0.0007 | 0.0018 | 0.0013 | 0.0042 | 0.0037 | 0.0149 | 0.0111 | 0.0556 | 0.0427 | 0.0899 | 0.0705 | 0.0803 | 0.0677 | 0.1118 | 0.0992 | 0.6413 | 0.7031 | 0.0011 | 0.0011 | 0.0040 | 0.0021 | 0.0078 | 0.0088 | 0.0221 | 0.0284 | 0.0709 | 0.0935 | 0.1183 | 0.1285 | 0.1002 | 0.1113 | 0.1330 | 0.1373 | 0.5425 | 0.4891 | 0.0010 | 0.0021 | 0.0040 | 0.0209 | 0.0659 | 0.0949 | 0.0885 | 0.1221 | 0.6005 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 524 | 141 | | 4317 | 6246 | 463.8 | 114.50 | 71.69 | 106.41 | 339 | 369 | 392 | 415 | 440 | 467 | 500 | 549 | 629 | 0.1005 | 628 | 1.211 | 95.02 | 37.48 | 1 | 0.0563 | 243 | 0.0011 | 40.02 | 7.058 | 0.1884 | 228193.0 | 119000000 | 66600000000 | 39500000000000 | 0.3905 | 0.2504 | 0.0000 | 0.0000 | 0.0012 | 0.0005 | 0.0054 | 0.0005 | 0.0173 | 0.0033 | 0.0695 | 0.0228 | 0.1245 | 0.0415 | 0.1318 | 0.0400 | 0.1690 | 0.0488 | 0.4814 | 0.8426 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0076 | 0.0009 | 0.0334 | 0.0140 | 0.0577 | 0.0244 | 0.0633 | 0.0147 | 0.0882 | 0.0216 | 0.7466 | 0.9244 | 0.0037 | 0.0000 | 0.0049 | 0.0057 | 0.0099 | 0.0345 | 0.0469 | 0.0690 | 0.0877 | 0.1293 | 0.1395 | 0.1264 | 0.1025 | 0.1264 | 0.1173 | 0.1494 | 0.4877 | 0.3592 | 0.0006 | 0.0051 | 0.0130 | 0.0395 | 0.0745 | 0.1072 | 0.0874 | 0.0987 | 0.5742 | 7 | 10 | 12 | 15 | 21 | 31 | 56 | 127 | 227 | 0.0902 | 12.13 | 4.224 | 0.6055 | 16459.4 | 5640000 | 2380000000 | 1160000000000 | 0.4828 | 0.1513 | 0.0532 | 0.0047 | 0.1894 | 0.0235 | 0.2990 | 0.0691 | 0.2359 | 0.1821 | 0.1196 | 0.2323 | 0.0698 | 0.2276 | 0.0266 | 0.1366 | 0.0000 | 0.0754 | 0.0066 | 0.0487 | 0.0000 | 0.0014 | 0.0000 | 0.0014 | 0.0022 | 0.0039 | 0.0129 | 0.0082 | 0.0533 | 0.0488 | 0.0787 | 0.0768 | 0.0566 | 0.0497 | 0.0981 | 0.0888 | 0.6983 | 0.7209 | 0.0000 | 0.0000 | 0.0013 | 0.0021 | 0.0058 | 0.0077 | 0.0154 | 0.0112 | 0.0624 | 0.0732 | 0.0977 | 0.0962 | 0.0585 | 0.0635 | 0.1145 | 0.1123 | 0.6444 | 0.6339 | 0.0000 | 0.0018 | 0.0035 | 0.0183 | 0.0589 | 0.0796 | 0.0654 | 0.0961 | 0.6765 | ||
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 902 | 772 | | 9805 | 18751 | 104.4 | 27.00 | 104.60 | 154.09 | 71 | 82 | 90 | 97 | 104 | 110 | 117 | 126 | 139 | 0.0633 | 1186 | 1.212 | 43.08 | 15.81 | 3 | 0.0114 | 112 | 0.0025 | 16.76 | 6.319 | 0.2683 | 11632.2 | 1370000 | 170000000 | 22000000000 | 0.4240 | 0.2204 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0007 | 0.0337 | 0.0037 | 0.0934 | 0.0179 | 0.1645 | 0.0465 | 0.1821 | 0.0638 | 0.1963 | 0.0903 | 0.3200 | 0.7770 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0001 | 0.0076 | 0.0017 | 0.0290 | 0.0096 | 0.0611 | 0.0214 | 0.0697 | 0.0191 | 0.0939 | 0.0324 | 0.7359 | 0.9158 | 0.0079 | 0.0174 | 0.0153 | 0.0349 | 0.0227 | 0.0654 | 0.0811 | 0.1497 | 0.1293 | 0.1715 | 0.1688 | 0.2035 | 0.1433 | 0.1206 | 0.1539 | 0.1206 | 0.2777 | 0.1163 | 0.0006 | 0.0026 | 0.0102 | 0.0307 | 0.0718 | 0.1201 | 0.1160 | 0.1498 | 0.4982 | 11 | 13 | 15 | 19 | 27 | 52 | 104 | 180 | 312 | 0.1458 | 19.88 | 4.207 | 0.6121 | 34684.3 | 18400000 | 13400000000 | 12900000000000 | 0.5548 | 0.1144 | 0.1016 | 0.0053 | 0.2744 | 0.0473 | 0.2848 | 0.2020 | 0.1392 | 0.1879 | 0.0992 | 0.2113 | 0.0544 | 0.1673 | 0.0200 | 0.0877 | 0.0168 | 0.0513 | 0.0096 | 0.0400 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0010 | 0.0124 | 0.0106 | 0.0714 | 0.0584 | 0.1103 | 0.0965 | 0.0716 | 0.0610 | 0.1148 | 0.1027 | 0.6169 | 0.6690 | 0.0000 | 0.0002 | 0.0014 | 0.0022 | 0.0034 | 0.0082 | 0.0241 | 0.0253 | 0.0928 | 0.1033 | 0.1418 | 0.1582 | 0.0932 | 0.1072 | 0.1495 | 0.1476 | 0.4938 | 0.4478 | 0.0004 | 0.0007 | 0.0034 | 0.0164 | 0.0820 | 0.1252 | 0.0852 | 0.1331 | 0.5536 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 165 | 346 | | 2161 | 4173 | 394.6 | 54.04 | 116.71 | 168.59 | 331 | 354 | 368 | 382 | 402 | 418 | 431 | 442 | 455 | 0.1006 | 420 | 1.034 | 84.17 | 27.73 | 4 | 0.0995 | 215 | 0.0035 | 8.75 | 5.908 | 0.3537 | 158617.0 | 64700000 | 26800000000 | 11200000000000 | 0.4254 | 0.2146 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0025 | 0.0000 | 0.0051 | 0.0028 | 0.0275 | 0.0151 | 0.0499 | 0.0420 | 0.0403 | 0.0193 | 0.0780 | 0.0297 | 0.7961 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0010 | 0.0000 | 0.0025 | 0.0028 | 0.0218 | 0.0151 | 0.0412 | 0.0420 | 0.0233 | 0.0193 | 0.0377 | 0.0297 | 0.8724 | 0.8906 | 0.0962 | 0.0000 | 0.2115 | 0.0000 | 0.2115 | 0.0000 | 0.1346 | 0.0000 | 0.1731 | 0.0000 | 0.0962 | 0.0000 | 0.0577 | 0.0000 | 0.0192 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0034 | 0.0034 | 0.0145 | 0.0298 | 0.0375 | 0.0486 | 0.0520 | 0.8090 | 14 | 17 | 20 | 25 | 38 | 61 | 108 | 180 | 346 | 0.1096 | 12.03 | 4.053 | 0.6346 | 42038.0 | 22900000 | 14900000000 | 10800000000000 | 0.3901 | 0.2553 | 0.0117 | 0.0015 | 0.0731 | 0.0030 | 0.2251 | 0.0345 | 0.1842 | 0.0811 | 0.1754 | 0.1532 | 0.1023 | 0.2387 | 0.0877 | 0.1517 | 0.0614 | 0.1276 | 0.0789 | 0.2087 | 0.0000 | 0.0006 | 0.0015 | 0.0000 | 0.0037 | 0.0019 | 0.0110 | 0.0146 | 0.0389 | 0.0285 | 0.0946 | 0.0856 | 0.0484 | 0.0463 | 0.0748 | 0.0533 | 0.7273 | 0.7692 | 0.0000 | 0.0000 | 0.0029 | 0.0022 | 0.0039 | 0.0011 | 0.0157 | 0.0176 | 0.0695 | 0.0812 | 0.1282 | 0.1405 | 0.0744 | 0.0768 | 0.1018 | 0.1098 | 0.6037 | 0.5708 | 0.0000 | 0.0017 | 0.0042 | 0.0135 | 0.0581 | 0.1053 | 0.0699 | 0.1003 | 0.6470 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 200 | 513 | | 11296 | 11224 | 660.4 | 94.02 | 95.02 | 136.71 | 543 | 587 | 617 | 640 | 661 | 683 | 708 | 735 | 774 | 0.1009 | 1133 | 0.918 | 133.74 | 44.91 | 2 | 0.0313 | 353 | 0.0006 | 79.90 | 7.739 | 0.1635 | 444990.0 | 305000000 | 213000000000 | 152000000000000 | 0.4251 | 0.2228 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0042 | 0.0006 | 0.0187 | 0.0081 | 0.0399 | 0.0182 | 0.0436 | 0.0113 | 0.0656 | 0.0181 | 0.8257 | 0.9436 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0022 | 0.0004 | 0.0107 | 0.0077 | 0.0240 | 0.0167 | 0.0219 | 0.0084 | 0.0314 | 0.0139 | 0.9090 | 0.9530 | 0.0074 | 0.0816 | 0.0173 | 0.0204 | 0.0222 | 0.0408 | 0.0937 | 0.2245 | 0.0912 | 0.2245 | 0.1307 | 0.2041 | 0.1097 | 0.0816 | 0.1233 | 0.1224 | 0.4044 | 0.0000 | 0.0016 | 0.0026 | 0.0092 | 0.0209 | 0.0527 | 0.0772 | 0.0800 | 0.1071 | 0.6486 | 12 | 16 | 20 | 27 | 38 | 53 | 81 | 138 | 272 | 0.0564 | 8.94 | 4.344 | 0.6275 | 27717.6 | 13300000 | 8080000000 | 5720000000000 | 0.4886 | 0.1747 | 0.0110 | 0.0020 | 0.0386 | 0.0109 | 0.0684 | 0.0288 | 0.1323 | 0.0387 | 0.2183 | 0.1107 | 0.1940 | 0.1846 | 0.1147 | 0.1166 | 0.1422 | 0.1509 | 0.0805 | 0.3568 | 0.0009 | 0.0007 | 0.0031 | 0.0037 | 0.0037 | 0.0072 | 0.0119 | 0.0120 | 0.0417 | 0.0400 | 0.0716 | 0.0744 | 0.0409 | 0.0423 | 0.0707 | 0.0596 | 0.7555 | 0.7601 | 0.0008 | 0.0004 | 0.0011 | 0.0022 | 0.0042 | 0.0043 | 0.0168 | 0.0173 | 0.0348 | 0.0381 | 0.0880 | 0.0934 | 0.0513 | 0.0510 | 0.0677 | 0.0636 | 0.7353 | 0.7297 | 0.0007 | 0.0010 | 0.0036 | 0.0116 | 0.0416 | 0.0819 | 0.0459 | 0.0714 | 0.7423 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1226 | 292 | | 1447 | 9024 | 65.1 | 24.28 | 181.44 | 210.82 | 35 | 44 | 51 | 57 | 63 | 69 | 76 | 85 | 96 | 0.0659 | 595 | 0.521 | 83.49 | 16.03 | 5 | 0.1714 | 248 | 0.0021 | 31.10 | 6.361 | 0.2003 | 4823.6 | 400876 | 37000000 | 3760000000 | 0.3867 | 0.2406 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0198 | 0.0028 | 0.0843 | 0.0170 | 0.1802 | 0.0405 | 0.2215 | 0.1008 | 0.1884 | 0.1329 | 0.1818 | 0.1951 | 0.1124 | 0.5108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0016 | 0.0109 | 0.0095 | 0.0465 | 0.0247 | 0.0812 | 0.0366 | 0.0663 | 0.0461 | 0.1238 | 0.0700 | 0.6693 | 0.8115 | 0.0049 | 0.0255 | 0.0099 | 0.0204 | 0.0025 | 0.0510 | 0.0765 | 0.1071 | 0.1284 | 0.1837 | 0.1778 | 0.1735 | 0.1654 | 0.1173 | 0.1407 | 0.1378 | 0.2938 | 0.1837 | 0.0015 | 0.0029 | 0.0059 | 0.0322 | 0.1025 | 0.1259 | 0.1127 | 0.1347 | 0.4817 | 19 | 26 | 41 | 64 | 97 | 142 | 205 | 308 | 477 | 0.0338 | 9.96 | 5.000 | 0.5659 | 77361.5 | 47900000 | 36100000000 | 30600000000000 | 0.5191 | 0.1524 | 0.0220 | 0.0015 | 0.0828 | 0.0094 | 0.1118 | 0.0342 | 0.1577 | 0.0768 | 0.2126 | 0.1412 | 0.1427 | 0.1684 | 0.1228 | 0.1273 | 0.0918 | 0.1446 | 0.0559 | 0.2967 | 0.0006 | 0.0005 | 0.0025 | 0.0012 | 0.0034 | 0.0009 | 0.0104 | 0.0092 | 0.0533 | 0.0431 | 0.0855 | 0.0726 | 0.0676 | 0.0528 | 0.0917 | 0.0820 | 0.6851 | 0.7378 | 0.0008 | 0.0013 | 0.0027 | 0.0022 | 0.0059 | 0.0040 | 0.0164 | 0.0211 | 0.0632 | 0.0723 | 0.1096 | 0.1159 | 0.0780 | 0.0858 | 0.1166 | 0.1204 | 0.6069 | 0.5768 | 0.0003 | 0.0020 | 0.0043 | 0.0143 | 0.0627 | 0.0953 | 0.0720 | 0.1040 | 0.6450 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 308 | 627 | | 7227 | 23465 | 215.5 | 41.93 | 145.25 | 174.73 | 162 | 178 | 191 | 202 | 212 | 224 | 237 | 252 | 273 | 0.0445 | 1045 | 1.162 | 108.98 | 41.15 | 1 | 0.0381 | 275 | 0.0011 | 40.67 | 7.077 | 0.1835 | 48189.1 | 11200000 | 2670000000 | 661000000000 | 0.4653 | 0.1920 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0045 | 0.0000 | 0.0153 | 0.0013 | 0.0650 | 0.0143 | 0.1342 | 0.0316 | 0.1506 | 0.0321 | 0.1783 | 0.0507 | 0.4501 | 0.8700 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0054 | 0.0001 | 0.0288 | 0.0103 | 0.0653 | 0.0222 | 0.0624 | 0.0119 | 0.0865 | 0.0207 | 0.7501 | 0.9347 | 0.0050 | 0.0140 | 0.0231 | 0.0698 | 0.0330 | 0.1302 | 0.0759 | 0.1628 | 0.1485 | 0.1907 | 0.1774 | 0.1628 | 0.1238 | 0.0977 | 0.1493 | 0.1163 | 0.2640 | 0.0558 | 0.0014 | 0.0020 | 0.0084 | 0.0341 | 0.0981 | 0.1388 | 0.1119 | 0.1380 | 0.4672 | 12 | 14 | 17 | 26 | 56 | 119 | 196 | 282 | 392 | 0.0424 | 27.68 | 5.411 | 0.4772 | 51628.4 | 24900000 | 14400000000 | 9560000000000 | 0.4794 | 0.1582 | 0.0785 | 0.0020 | 0.2700 | 0.0215 | 0.3485 | 0.1855 | 0.1364 | 0.2031 | 0.0927 | 0.2112 | 0.0438 | 0.1640 | 0.0210 | 0.1007 | 0.0057 | 0.0672 | 0.0034 | 0.0448 | 0.0001 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0004 | 0.0088 | 0.0057 | 0.0525 | 0.0474 | 0.0960 | 0.0821 | 0.0705 | 0.0572 | 0.1013 | 0.0869 | 0.6700 | 0.7200 | 0.0001 | 0.0009 | 0.0013 | 0.0022 | 0.0034 | 0.0060 | 0.0176 | 0.0207 | 0.0700 | 0.0762 | 0.1210 | 0.1334 | 0.0883 | 0.0944 | 0.1155 | 0.1235 | 0.5829 | 0.5428 | 0.0000 | 0.0003 | 0.0021 | 0.0129 | 0.0602 | 0.1081 | 0.0860 | 0.1052 | 0.6252 |