High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 910 235 image if available 5650 9484 613.1 99.25 15.85 17.71 472 537 575 601 623 643 663 690 733 0.0777 737 0.760 87.05 15.26 1 0.0388 219 0.0011 30.87 7.107 0.2252 385716.0
248000000
163000000000
109000000000000
0.3922 0.2485 0.0005 0.0000 0.0002 0.0000 0.0016 0.0000 0.0043 0.0007 0.0256 0.0133 0.0488 0.0204 0.0442 0.0136 0.0551 0.0226 0.8197 0.9294 0.0002 0.0000 0.0000 0.0000 0.0000 0.0000 0.0012 0.0007 0.0151 0.0133 0.0258 0.0204 0.0208 0.0122 0.0270 0.0190 0.9099 0.9344 0.0036 0.2000 0.0145 0.8000 0.0163 0.0000 0.0435 0.0000 0.0870 0.0000 0.1431 0.0000 0.0833 0.0000 0.1105 0.0000 0.4982 0.0000 0.0019 0.0019 0.0061 0.0129 0.0399 0.0633 0.0672 0.0987 0.7081 5 7 8 9 11 13 15 20 32 0.2512 0.44 1.751 0.7487 564.9
50306.4
9130000
2400000000
0.5918 0.0979 0.0534 0.0357 0.0820 0.0510 0.0996 0.0522 0.1245 0.0695 0.1572 0.0948 0.1789 0.1024 0.1727 0.1371 0.1011 0.1779 0.0306 0.2793 0.0244 0.0248 0.0307 0.0322 0.0359 0.0315 0.0432 0.0424 0.0663 0.0619 0.0788 0.0696 0.0772 0.0803 0.1043 0.1080 0.5391 0.5493 0.0219 0.0129 0.0172 0.0233 0.0256 0.0259 0.0339 0.0291 0.0516 0.0505 0.0793 0.0627 0.0652 0.0524 0.0814 0.0996 0.6239 0.6436 0.0286 0.0414 0.0352 0.0447 0.0521 0.0660 0.0663 0.1015 0.5642
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 919 347 image if available 5602 6122 469.4 79.21 27.49 47.62 357 396 427 455 479 496 513 531 559 0.1042 638 0.998 133.18 37.86 1 0.0605 339 0.0017 16.11 6.642 0.3084 226643.0
112000000
57000000000
29500000000000
0.4201 0.2305 0.0005 0.0000 0.0014 0.0000 0.0033 0.0000 0.0068 0.0007 0.0224 0.0104 0.0352 0.0294 0.0373 0.0137 0.0623 0.0225 0.8308 0.9233 0.0002 0.0000 0.0010 0.0000 0.0025 0.0000 0.0042 0.0005 0.0136 0.0097 0.0247 0.0272 0.0207 0.0098 0.0262 0.0177 0.9067 0.9351 0.0187 0.0000 0.0093 0.0541 0.0093 0.0811 0.0318 0.1622 0.0486 0.1892 0.0542 0.1892 0.0710 0.0811 0.0841 0.1351 0.6729 0.1081 0.0000 0.0020 0.0049 0.0120 0.0273 0.0462 0.0524 0.0908 0.7645 8 10 12 14 15 17 20 29 50 0.3237 1.45 2.056 0.8309 3023.4
1020000
532000000
337000000000
0.5358 0.1270 0.0965 0.0392 0.0856 0.0530 0.0911 0.0723 0.1111 0.0933 0.1840 0.1154 0.1858 0.1198 0.1056 0.1375 0.1093 0.1452 0.0310 0.2242 0.0300 0.0239 0.0257 0.0316 0.0178 0.0421 0.0165 0.0541 0.0484 0.0733 0.0772 0.0824 0.0502 0.0798 0.0876 0.0900 0.6467 0.5229 0.0018 0.0011 0.0092 0.0063 0.0111 0.0138 0.0129 0.0180 0.0563 0.0624 0.0969 0.0963 0.0572 0.0709 0.0895 0.1270 0.6651 0.6042 0.0092 0.0077 0.0061 0.0146 0.0452 0.0958 0.0598 0.0782 0.6835
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 353 558 image if available 3264 13261 567.7 97.23 20.25 30.53 423 480 524 555 578 601 624 651 686 0.0525 696 0.829 83.26 24.17 2 0.0757 247 0.0012 24.55 6.947 0.2311 331741.0
199000000
122000000000
75900000000000
0.3761 0.2603 0.0000 0.0000 0.0000 0.0000 0.0013 0.0000 0.0042 0.0015 0.0348 0.0117 0.0809 0.0329 0.0637 0.0151 0.0926 0.0194 0.7227 0.9195 0.0000 0.0000 0.0000 0.0000 0.0007 0.0000 0.0018 0.0012 0.0138 0.0117 0.0348 0.0322 0.0210 0.0129 0.0246 0.0169 0.9033 0.9251 0.0000 0.0000 0.0134 0.0000 0.0267 0.0000 0.0829 0.2000 0.1337 0.2000 0.2086 0.2000 0.1310 0.2000 0.1230 0.2000 0.2807 0.0000 0.0000 0.0011 0.0022 0.0117 0.0458 0.1011 0.0844 0.1000 0.6536 6 8 9 10 11 13 15 19 43 0.3560 0.58 1.966 0.8565 1342.4
217327
52700000
15600000000
0.5872 0.1138 0.0827 0.0402 0.0911 0.0460 0.0905 0.0583 0.1079 0.0708 0.1235 0.1009 0.1307 0.1071 0.1589 0.1225 0.1457 0.1493 0.0689 0.3048 0.0327 0.0279 0.0346 0.0300 0.0335 0.0375 0.0372 0.0451 0.0380 0.0643 0.0515 0.0758 0.0560 0.0781 0.0861 0.0967 0.6304 0.5445 0.0142 0.0053 0.0137 0.0053 0.0132 0.0107 0.0179 0.0165 0.0189 0.0256 0.0344 0.0373 0.0387 0.0453 0.0783 0.0719 0.7708 0.7821 0.0197 0.0239 0.0239 0.0337 0.0322 0.0405 0.0348 0.0594 0.7319
Hs 578T Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 206 921 image if available 453 2987 114.8 45.79 54.07 106.69 60 72 83 92 107 124 140 163 186 0.1145 342 0.878 44.91 11.18 2 0.2517 114 0.0028 90.22 5.942 0.1266 15262.5
2270000
364000000
61700000000
0.3487 0.2630 0.0000 0.0000 0.0000 0.0000 0.1136 0.0107 0.1894 0.0143 0.2803 0.0964 0.1667 0.1607 0.1212 0.1214 0.0833 0.2250 0.0455 0.3714 0.0000 0.0000 0.0000 0.0000 0.0000 0.0027 0.0217 0.0080 0.0797 0.0507 0.0870 0.0667 0.0833 0.0453 0.1232 0.0907 0.6051 0.7360 0.0000 0.0105 0.0000 0.0000 0.0069 0.0000 0.0417 0.0526 0.1389 0.1263 0.1181 0.1895 0.1042 0.1158 0.1458 0.1579 0.4444 0.3474 0.0000 0.0000 0.0100 0.0348 0.0796 0.1095 0.0945 0.0746 0.5970 19 21 22 23 25 27 30 40 83 0.1621 4.97 2.567 0.7206 14301.8
8310000
5840000000
4430000000000
0.6250 0.1113 0.0402 0.0406 0.1609 0.0449 0.1954 0.0684 0.2471 0.0983 0.1667 0.1581 0.1207 0.1859 0.0517 0.1838 0.0115 0.1496 0.0057 0.0705 0.0018 0.0239 0.0164 0.0239 0.0236 0.0290 0.0436 0.0365 0.1127 0.0982 0.1145 0.1159 0.0836 0.0882 0.1309 0.1461 0.4727 0.4383 0.0080 0.0000 0.0133 0.0215 0.0080 0.0000 0.0372 0.0307 0.1197 0.1350 0.1383 0.1350 0.0851 0.0890 0.1463 0.1442 0.4441 0.4448 0.0022 0.0130 0.0152 0.0304 0.1326 0.1152 0.0870 0.1413 0.4630
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 953 241 image if available 4452 16651 514.3 202.79 16.75 22.48 264 314 365 425 496 574 650 721 776 0.0610 1016 0.831 150.81 30.46 9 0.0806 359 0.0007 46.67 7.524 0.1977 305620.0
203000000
146000000000
112000000000000
0.3891 0.2375 0.0008 0.0022 0.0000 0.0000 0.0142 0.0022 0.0334 0.0103 0.0943 0.0357 0.1060 0.0600 0.1018 0.0527 0.1277 0.0681 0.5217 0.7688 0.0000 0.0003 0.0000 0.0000 0.0015 0.0003 0.0036 0.0052 0.0259 0.0196 0.0353 0.0304 0.0230 0.0232 0.0383 0.0312 0.8724 0.8898 0.0000 0.0000 0.0000 0.0044 0.0019 0.0044 0.0045 0.0166 0.0408 0.0376 0.0388 0.0564 0.0323 0.0431 0.0511 0.0818 0.8305 0.7558 0.0000 0.0000 0.0000 0.0067 0.0262 0.0419 0.0295 0.0409 0.8548 6 7 8 9 11 14 17 22 30 0.1712 0.40 1.575 0.6158 785.9
143855
50100000
21000000000
0.6171 0.0868 0.0605 0.0488 0.0678 0.0590 0.0946 0.0585 0.1398 0.0738 0.1565 0.0814 0.1773 0.0904 0.1603 0.1323 0.1067 0.1903 0.0365 0.2655 0.0178 0.0287 0.0157 0.0319 0.0185 0.0277 0.0267 0.0319 0.0491 0.0406 0.0697 0.0463 0.0717 0.0582 0.1168 0.0921 0.6140 0.6425 0.0160 0.0168 0.0214 0.0291 0.0295 0.0412 0.0447 0.0496 0.0736 0.0814 0.0894 0.0941 0.1054 0.1129 0.1416 0.1313 0.4783 0.4436 0.0152 0.0164 0.0269 0.0290 0.0574 0.0696 0.0884 0.1384 0.5589
MDA-MB-231 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 248 500 image if available 1039 2688 496.1 98.73 39.06 62.95 376 424 458 485 504 521 536 562 631 0.1365 367 0.740 130.00 22.83 1 0.2849 296 0.0017 65.54 6.527 0.1617 255811.0
136000000
73900000000
41200000000000
0.4036 0.2366 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0054 0.0020 0.0499 0.0318 0.0823 0.0417 0.0702 0.0328 0.0931 0.0557 0.6991 0.8360 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0011 0.0020 0.0324 0.0307 0.0525 0.0396 0.0357 0.0277 0.0558 0.0455 0.8225 0.8546 0.0000 0.0000 0.0000 0.2000 0.0065 0.6000 0.0258 0.2000 0.0710 0.0000 0.0903 0.0000 0.0645 0.0000 0.1032 0.0000 0.6387 0.0000 0.0000 0.0017 0.0017 0.0174 0.0522 0.0922 0.0783 0.0939 0.6626 7 8 10 13 15 18 23 43 112 0.1239 2.12 3.167 0.7441 5486.9
1350000
417000000
146000000000
0.5373 0.1116 0.0154 0.0541 0.0538 0.0510 0.0846 0.0318 0.1231 0.0701 0.1231 0.0987 0.2077 0.0955 0.1462 0.1178 0.1538 0.2102 0.0923 0.2707 0.0031 0.0211 0.0108 0.0199 0.0093 0.0112 0.0170 0.0211 0.0216 0.0373 0.0386 0.0398 0.0448 0.0460 0.0802 0.1007 0.7747 0.7027 0.0039 0.0020 0.0039 0.0000 0.0019 0.0041 0.0135 0.0122 0.0251 0.0245 0.0290 0.0306 0.0444 0.0510 0.0734 0.0592 0.8050 0.8163 0.0070 0.0053 0.0088 0.0140 0.0298 0.0385 0.0403 0.0788 0.7776
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 95 131 image if available 989 1640 89.4 13.84 29.47 62.84 71 77 82 85 89 93 96 101 107 0.2116 347 0.177 169.76 32.53 2 0.8817 872 0.0651 1.08 3.063 0.6829 8181.5
766522
73500000
7210000000
0.3997 0.2450 0.0013 0.0000 0.0025 0.0000 0.0063 0.0000 0.0304 0.0061 0.0608 0.0348 0.0989 0.0583 0.1343 0.0409 0.1926 0.0502 0.4728 0.8096 0.0011 0.0000 0.0011 0.0000 0.0022 0.0000 0.0169 0.0051 0.0371 0.0293 0.0573 0.0526 0.0629 0.0303 0.0843 0.0415 0.7371 0.8413 0.0594 0.0000 0.1089 0.3333 0.1188 0.2500 0.1485 0.2500 0.1485 0.0833 0.1782 0.0833 0.0594 0.0000 0.0792 0.0000 0.0990 0.0000 0.0019 0.0077 0.0232 0.0522 0.0754 0.1006 0.1528 0.2147 0.3714 8 10 12 13 15 17 20 26 43 0.3370 1.57 1.900 0.7940 4815.1
2160000
1340000000
961000000000
0.6590 0.0663 0.0476 0.0571 0.1429 0.0571 0.1905 0.0813 0.2434 0.1099 0.2487 0.1429 0.0794 0.1868 0.0476 0.1890 0.0000 0.1341 0.0000 0.0418 0.0128 0.0413 0.0434 0.0366 0.0561 0.0461 0.0918 0.0636 0.1429 0.0986 0.1709 0.1574 0.1301 0.1558 0.1071 0.1558 0.2449 0.2448 0.0246 0.0057 0.0148 0.0230 0.0296 0.0345 0.0788 0.0575 0.1478 0.1609 0.1773 0.2126 0.1281 0.1149 0.1232 0.1437 0.2759 0.2471 0.0223 0.0335 0.0520 0.0632 0.1561 0.1710 0.1227 0.1190 0.2602
SK-BR-3 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 1130 267 image if available 5490 23038 164.0 66.56 28.31 61.33 83 103 121 140 156 173 190 215 271 0.0512 1180 0.983 61.59 20.03 5 0.0288 158 0.0023 6.37 6.316 0.3881 31316.4
6760000
1600000000
408000000000
0.3733 0.2534 0.0000 0.0000 0.0019 0.0025 0.0077 0.0028 0.0178 0.0083 0.0548 0.0230 0.0836 0.0418 0.1000 0.0452 0.1629 0.0593 0.5714 0.8171 0.0000 0.0000 0.0011 0.0015 0.0023 0.0018 0.0056 0.0051 0.0158 0.0124 0.0237 0.0218 0.0259 0.0218 0.0440 0.0294 0.8816 0.9062 0.0027 0.0011 0.0075 0.0054 0.0137 0.0087 0.0239 0.0130 0.0321 0.0369 0.0498 0.0510 0.0546 0.0304 0.0539 0.0542 0.7618 0.7993 0.0000 0.0012 0.0056 0.0164 0.0308 0.0504 0.0496 0.0712 0.7747 7 9 10 12 13 15 18 25 46 0.1947 4.25 2.622 0.7761 4562.8
1730000
803000000
408000000000
0.5689 0.1210 0.0523 0.0587 0.0562 0.0581 0.0812 0.0637 0.1251 0.0665 0.1413 0.0729 0.1613 0.0863 0.1935 0.0999 0.1268 0.1500 0.0623 0.3441 0.0140 0.0361 0.0138 0.0353 0.0177 0.0353 0.0272 0.0346 0.0400 0.0414 0.0560 0.0533 0.0641 0.0585 0.0971 0.0880 0.6701 0.6175 0.0057 0.0047 0.0093 0.0061 0.0131 0.0140 0.0191 0.0201 0.0508 0.0635 0.0669 0.0793 0.0770 0.0840 0.1123 0.1231 0.6459 0.6053 0.0104 0.0106 0.0164 0.0205 0.0425 0.0614 0.0594 0.1068 0.6718
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 779 488 image if available 1658 7515 661.2 127.45 21.12 72.35 472 534 588 636 672 708 749 791 831 0.0896 673 1.056 79.26 20.40 1 0.1128 187 0.0037 8.63 5.897 0.3770 453371.0
321000000
233000000000
172000000000000
0.3992 0.2328 0.0000 0.0000 0.0020 0.0000 0.0029 0.0000 0.0098 0.0018 0.0479 0.0231 0.0685 0.0358 0.0607 0.0219 0.0881 0.0328 0.7202 0.8846 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0022 0.0018 0.0283 0.0231 0.0358 0.0358 0.0253 0.0219 0.0365 0.0328 0.8718 0.8846 0.0000 0.0000 0.0000 0.0000 0.0125 0.0000 0.0344 0.0000 0.0531 0.0000 0.0531 0.0000 0.0688 0.0000 0.1000 0.0000 0.6781 0.0000 0.0011 0.0011 0.0034 0.0135 0.0270 0.0529 0.0450 0.0541 0.8018 4 5 6 7 7 8 9 12 17 0.1063 2.38 1.499 0.4250 5680.0
3330000
2380000000
1890000000000
0.4909 0.1207 0.0780 0.0610 0.2110 0.0749 0.2844 0.0999 0.2661 0.1207 0.0826 0.1914 0.0505 0.1692 0.0092 0.0874 0.0138 0.0707 0.0046 0.1248 0.0181 0.0352 0.0233 0.0424 0.0194 0.0488 0.0440 0.0456 0.0660 0.0697 0.0699 0.0689 0.0621 0.0817 0.0776 0.0961 0.6197 0.5116 0.0000 0.0000 0.0000 0.0019 0.0054 0.0000 0.0090 0.0189 0.0667 0.0682 0.1189 0.0928 0.0360 0.0625 0.0811 0.0795 0.6829 0.6761 0.0016 0.0064 0.0096 0.0305 0.0595 0.0691 0.0740 0.0804 0.6688
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 646 621 image if available 554 3317 275.3 19.34 19.44 28.31 251 261 267 272 276 281 286 292 299 0.1007 334 0.832 128.55 29.97 1 0.5108 283 0.0078 11.20 5.111 0.3312 76161.1
21200000
5910000000
1660000000000
0.3922 0.2458 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0453 0.0451 0.0652 0.0650 0.0380 0.0307 0.0580 0.0469 0.7935 0.8123 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0453 0.0451 0.0652 0.0650 0.0380 0.0307 0.0580 0.0469 0.7935 0.8123 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0067 0.0100 0.0300 0.0533 0.0900 0.1667 0.1333 0.1567 0.3533 7 8 9 9 11 12 15 22 33 0.0979 0.55 1.508 0.4506 1178.9
161332
29100000
5860000000
0.5686 0.1153 0.0480 0.0687 0.1051 0.0634 0.1471 0.0569 0.1952 0.0838 0.2462 0.0967 0.1532 0.1267 0.0811 0.1590 0.0210 0.2105 0.0030 0.1343 0.0121 0.0433 0.0141 0.0377 0.0121 0.0314 0.0313 0.0328 0.0555 0.0370 0.0757 0.0656 0.0858 0.0628 0.1171 0.1172 0.5964 0.5722 0.0091 0.0139 0.0106 0.0239 0.0152 0.0359 0.0410 0.0478 0.0699 0.0896 0.1307 0.1116 0.1185 0.1116 0.1413 0.1434 0.4635 0.4223 0.0059 0.0059 0.0118 0.0403 0.0557 0.0853 0.0936 0.1256 0.5758
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 386 707 image if available 13530 19255 474.1 126.99 20.39 53.21 304 394 439 470 494 519 545 573 609 0.0718 1383 0.981 73.41 26.31 10 0.0152 205 0.0008 44.28 7.548 0.2080 240855.0
127000000
69400000000
38700000000000
0.5339 0.1308 0.0006 0.0000 0.0010 0.0001 0.0043 0.0006 0.0142 0.0018 0.0585 0.0189 0.1017 0.0371 0.0863 0.0264 0.1091 0.0426 0.6244 0.8725 0.0001 0.0000 0.0002 0.0001 0.0001 0.0000 0.0015 0.0008 0.0170 0.0145 0.0361 0.0292 0.0214 0.0147 0.0347 0.0225 0.8889 0.9183 0.0031 0.0204 0.0058 0.0051 0.0170 0.0636 0.0458 0.1018 0.1021 0.1552 0.1378 0.1578 0.1116 0.1603 0.1412 0.1425 0.4357 0.1934 0.0001 0.0006 0.0021 0.0108 0.0390 0.0782 0.0620 0.0866 0.7204 6 7 8 9 10 11 13 16 31 0.4315 1.39 1.784 0.8626 3247.0
1790000
1370000000
1200000000000
0.6652 0.0672 0.0808 0.0848 0.0820 0.0869 0.1165 0.0731 0.1440 0.0714 0.1647 0.0831 0.1540 0.1070 0.1277 0.1051 0.0977 0.1288 0.0326 0.2598 0.0277 0.0558 0.0224 0.0571 0.0301 0.0465 0.0388 0.0399 0.0653 0.0505 0.0774 0.0737 0.0629 0.0667 0.0863 0.0911 0.5891 0.5187 0.0078 0.0032 0.0078 0.0050 0.0078 0.0140 0.0168 0.0235 0.0588 0.0587 0.0748 0.0898 0.0643 0.0700 0.1019 0.1020 0.6599 0.6339 0.0183 0.0157 0.0223 0.0265 0.0465 0.0750 0.0550 0.0917 0.6490
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1120 374 image if available 1013 7639 932.9 280.82 18.77 68.99 520 632 745 866 972 1068 1154 1217 1274 0.0730 558 0.951 63.01 16.64 2 0.1382 140 0.0016 66.58 6.568 0.1620 949022.0
1030000000
1160000000000
1.34E+15
0.2997 0.3332 0.0000 0.0000 0.0000 0.0000 0.0028 0.0013 0.0141 0.0025 0.1155 0.0401 0.2197 0.0877 0.1380 0.0401 0.1662 0.0677 0.3437 0.7607 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0042 0.0000 0.0368 0.0311 0.0637 0.0681 0.0326 0.0219 0.0425 0.0381 0.8201 0.8408 0.0000 0.0000 0.0000 0.0145 0.0000 0.0000 0.0171 0.0580 0.0484 0.1449 0.0883 0.1014 0.0570 0.1014 0.0712 0.2029 0.7179 0.3768 0.0000 0.0000 0.0000 0.0000 0.0427 0.0816 0.0278 0.0594 0.7885 4 5 6 6 8 8 9 11 13 0.1323 2.99 1.460 0.4553 5111.7
3110000
2280000000
1870000000000
0.4103 0.1711 0.2687 0.1623 0.2463 0.1455 0.2015 0.1545 0.2612 0.1636 0.0224 0.1325 0.0000 0.1273 0.0000 0.0688 0.0000 0.0416 0.0000 0.0039 0.0357 0.1050 0.0187 0.0915 0.0221 0.0882 0.0306 0.0747 0.0629 0.0571 0.0510 0.0756 0.0952 0.0655 0.0799 0.0756 0.6037 0.3669 0.0000 0.0000 0.0022 0.0000 0.0066 0.0000 0.0176 0.0143 0.0683 0.0903 0.1101 0.1021 0.0551 0.0570 0.0991 0.1069 0.6410 0.6295 0.0100 0.0060 0.0040 0.0260 0.0680 0.0820 0.0740 0.0900 0.6400
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 972 177 image if available 395 12546 117.2 19.48 22.21 93.56 93 98 104 109 113 121 128 137 146 0.0524 657 1.105 42.05 12.04 0 0.2380 94 0.0471 0.93 3.300 0.6696 14103.0
1740000
221000000
28700000000
0.3949 0.2407 0.0000 0.0000 0.0102 0.0000 0.0136 0.0000 0.0374 0.0127 0.0646 0.0433 0.1224 0.0738 0.1327 0.0585 0.1565 0.0916 0.4626 0.7201 0.0000 0.0000 0.0028 0.0000 0.0085 0.0000 0.0254 0.0127 0.0366 0.0430 0.0732 0.0734 0.0704 0.0532 0.0789 0.0658 0.7042 0.7519 0.0000 0.0000 0.0164 1.0000 0.0492 0.0000 0.0820 0.0000 0.0984 0.0000 0.1639 0.0000 0.1148 0.0000 0.1967 0.0000 0.2787 0.0000 0.0055 0.0055 0.0000 0.0497 0.0552 0.0718 0.0939 0.0939 0.6243 4 5 6 7 7 8 9 10 14 0.1205 3.55 1.534 0.4274 9246.7
8900000
10500000000
13500000000000
0.4645 0.1926 0.0604 0.1758 0.1758 0.0687 0.2582 0.0929 0.3462 0.1414 0.1099 0.1980 0.0385 0.1737 0.0110 0.0747 0.0000 0.0485 0.0000 0.0263 0.0000 0.0672 0.0020 0.0227 0.0099 0.0180 0.0159 0.0164 0.0556 0.0469 0.0724 0.0618 0.0764 0.0641 0.1022 0.0821 0.6657 0.6208 0.0024 0.0000 0.0000 0.0000 0.0024 0.0026 0.0182 0.0140 0.0654 0.0727 0.0956 0.0969 0.0690 0.0625 0.0920 0.0982 0.6550 0.6531 0.0000 0.0022 0.0065 0.0196 0.0577 0.0882 0.0719 0.0882 0.6656
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1200 960 image if available 312 3292 82.5 11.29 23.21 72.43 68 73 76 79 82 86 89 93 97 0.1206 397 1.136 33.29 11.66 2 0.2724 85 0.0754 0.90 2.811 0.6827 6932.2
592793
51500000
4550000000
0.3990 0.2389 0.0037 0.0000 0.0000 0.0032 0.0112 0.0000 0.0485 0.0096 0.0672 0.0737 0.1194 0.0833 0.0933 0.0481 0.1604 0.0705 0.4963 0.7115 0.0034 0.0000 0.0000 0.0032 0.0069 0.0000 0.0206 0.0096 0.0481 0.0737 0.0997 0.0833 0.0378 0.0481 0.0722 0.0705 0.7113 0.7115 0.0870 0.0000 0.1304 0.0000 0.2174 0.0000 0.2609 0.0000 0.0870 0.0000 0.1304 0.0000 0.0435 0.0000 0.0000 0.0000 0.0435 0.0000 0.0120 0.0180 0.0299 0.0539 0.0898 0.2275 0.0958 0.1078 0.3653 5 6 8 8 9 10 11 12 16 0.2788 2.99 1.539 0.6666 5783.0
2740000
1470000000
851000000000
0.3576 0.2571 0.1333 0.2774 0.2167 0.1473 0.3500 0.1130 0.1833 0.1541 0.0833 0.1336 0.0333 0.1199 0.0000 0.0411 0.0000 0.0103 0.0000 0.0034 0.0217 0.1656 0.0072 0.0879 0.0109 0.0573 0.0217 0.0613 0.0435 0.0327 0.0942 0.0675 0.0471 0.0409 0.0870 0.0695 0.6667 0.4172 0.0000 0.0000 0.0093 0.0000 0.0046 0.0000 0.0139 0.0203 0.0509 0.0711 0.1111 0.0863 0.0556 0.0761 0.0787 0.0863 0.6759 0.6599 0.0042 0.0042 0.0211 0.0253 0.0506 0.0717 0.0717 0.0928 0.6582