High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 420 | 407 | | 25302 | 42176 | 171.8 | 49.38 | 147.43 | 237.23 | 112 | 132 | 146 | 157 | 168 | 180 | 193 | 209 | 237 | 0.0462 | 1948 | 0.760 | 83.49 | 25.63 | 2 | 0.0098 | 247 | 0.0005 | 62.65 | 7.913 | 0.1534 | 31965.7 | 6390000 | 1360000000 | 309000000000 | 0.4638 | 0.1892 | 0.0006 | 0.0001 | 0.0017 | 0.0002 | 0.0040 | 0.0010 | 0.0225 | 0.0052 | 0.0688 | 0.0183 | 0.1379 | 0.0386 | 0.1421 | 0.0455 | 0.1734 | 0.0654 | 0.4489 | 0.8256 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0012 | 0.0003 | 0.0082 | 0.0023 | 0.0254 | 0.0102 | 0.0549 | 0.0202 | 0.0570 | 0.0218 | 0.0776 | 0.0313 | 0.7745 | 0.9136 | 0.0031 | 0.0052 | 0.0063 | 0.0083 | 0.0203 | 0.0270 | 0.0520 | 0.0513 | 0.0941 | 0.0896 | 0.1249 | 0.1265 | 0.0922 | 0.0926 | 0.1087 | 0.1087 | 0.4984 | 0.4909 | 0.0012 | 0.0029 | 0.0075 | 0.0285 | 0.0609 | 0.0972 | 0.0953 | 0.1135 | 0.5931 | 15 | 18 | 20 | 25 | 35 | 63 | 116 | 226 | 460 | 0.1298 | 9.91 | 4.162 | 0.6635 | 78010.9 | 64000000 | 64700000000 | 75200000000000 | 0.5804 | 0.1109 | 0.0461 | 0.0048 | 0.1404 | 0.0150 | 0.1993 | 0.0735 | 0.1444 | 0.1068 | 0.1579 | 0.1632 | 0.1301 | 0.1918 | 0.0879 | 0.1258 | 0.0525 | 0.1221 | 0.0414 | 0.1970 | 0.0003 | 0.0004 | 0.0022 | 0.0006 | 0.0037 | 0.0016 | 0.0126 | 0.0129 | 0.0488 | 0.0445 | 0.0771 | 0.0675 | 0.0547 | 0.0498 | 0.0753 | 0.0744 | 0.7252 | 0.7484 | 0.0003 | 0.0004 | 0.0020 | 0.0030 | 0.0029 | 0.0043 | 0.0165 | 0.0197 | 0.0624 | 0.0647 | 0.0891 | 0.0998 | 0.0647 | 0.0673 | 0.0892 | 0.0949 | 0.6728 | 0.6458 | 0.0008 | 0.0012 | 0.0033 | 0.0140 | 0.0563 | 0.0848 | 0.0591 | 0.0848 | 0.6958 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1246 | 203 | | 5974 | 10831 | 309.6 | 60.88 | 229.94 | 346.15 | 229 | 256 | 278 | 295 | 310 | 324 | 340 | 361 | 389 | 0.0792 | 858 | 0.570 | 89.36 | 14.42 | 1 | 0.0336 | 201 | 0.0010 | 42.49 | 7.110 | 0.1903 | 99557.1 | 33100000 | 11400000000 | 4030000000000 | 0.4350 | 0.2143 | 0.0005 | 0.0000 | 0.0005 | 0.0003 | 0.0049 | 0.0003 | 0.0155 | 0.0019 | 0.0608 | 0.0167 | 0.1043 | 0.0263 | 0.1316 | 0.0288 | 0.1592 | 0.0436 | 0.5228 | 0.8820 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0010 | 0.0003 | 0.0058 | 0.0014 | 0.0243 | 0.0127 | 0.0467 | 0.0199 | 0.0505 | 0.0136 | 0.0664 | 0.0216 | 0.8047 | 0.9302 | 0.0043 | 0.0274 | 0.0228 | 0.0479 | 0.0390 | 0.0548 | 0.1029 | 0.1644 | 0.1484 | 0.1986 | 0.1582 | 0.1712 | 0.1387 | 0.1164 | 0.1278 | 0.1370 | 0.2579 | 0.0822 | 0.0007 | 0.0027 | 0.0050 | 0.0219 | 0.0757 | 0.1286 | 0.1173 | 0.1591 | 0.4890 | 4 | 7 | 9 | 12 | 19 | 103 | 267 | 475 | 758 | 0.0830 | 58.23 | 4.859 | 0.4659 | 172683.0 | 171000000 | 200000000000 | 267000000000000 | 0.3514 | 0.2613 | 0.0254 | 0.0000 | 0.1404 | 0.0131 | 0.2860 | 0.0672 | 0.2014 | 0.1345 | 0.1726 | 0.1921 | 0.0660 | 0.2192 | 0.0609 | 0.1432 | 0.0220 | 0.1188 | 0.0254 | 0.1118 | 0.0000 | 0.0000 | 0.0003 | 0.0010 | 0.0008 | 0.0010 | 0.0074 | 0.0049 | 0.0296 | 0.0227 | 0.0565 | 0.0462 | 0.0486 | 0.0366 | 0.0600 | 0.0545 | 0.7969 | 0.8332 | 0.0003 | 0.0000 | 0.0003 | 0.0017 | 0.0022 | 0.0034 | 0.0078 | 0.0112 | 0.0441 | 0.0454 | 0.0789 | 0.0919 | 0.0582 | 0.0671 | 0.0851 | 0.0824 | 0.7230 | 0.6969 | 0.0006 | 0.0009 | 0.0017 | 0.0086 | 0.0356 | 0.0710 | 0.0529 | 0.0690 | 0.7597 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 317 | 690 | | 3464 | 11834 | 342.0 | 75.63 | 178.33 | 204.51 | 250 | 275 | 296 | 316 | 334 | 353 | 374 | 407 | 449 | 0.0724 | 857 | 0.954 | 122.41 | 43.14 | 1 | 0.0944 | 327 | 0.0010 | 39.91 | 7.112 | 0.1793 | 122696.0 | 46100000 | 18100000000 | 7380000000000 | 0.3949 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0033 | 0.0000 | 0.0135 | 0.0025 | 0.0652 | 0.0246 | 0.1226 | 0.0467 | 0.1086 | 0.0418 | 0.1407 | 0.0563 | 0.5461 | 0.8278 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0061 | 0.0015 | 0.0275 | 0.0178 | 0.0582 | 0.0338 | 0.0453 | 0.0228 | 0.0735 | 0.0336 | 0.7874 | 0.8906 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0061 | 0.0000 | 0.0350 | 0.0000 | 0.1035 | 0.0000 | 0.1461 | 0.0000 | 0.0989 | 0.0000 | 0.1370 | 0.0000 | 0.4718 | 0.0000 | 0.0006 | 0.0025 | 0.0063 | 0.0151 | 0.0753 | 0.0834 | 0.0997 | 0.1173 | 0.5997 | 15 | 19 | 31 | 55 | 87 | 145 | 230 | 323 | 470 | 0.0227 | 19.50 | 5.564 | 0.4886 | 73621.5 | 41900000 | 28500000000 | 21900000000000 | 0.6117 | 0.0866 | 0.0329 | 0.0009 | 0.1078 | 0.0038 | 0.2187 | 0.0509 | 0.1920 | 0.0937 | 0.1694 | 0.1715 | 0.1283 | 0.2068 | 0.0688 | 0.1413 | 0.0431 | 0.1328 | 0.0390 | 0.1983 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0009 | 0.0090 | 0.0061 | 0.0363 | 0.0348 | 0.0722 | 0.0563 | 0.0539 | 0.0445 | 0.0705 | 0.0661 | 0.7557 | 0.7909 | 0.0003 | 0.0006 | 0.0018 | 0.0012 | 0.0021 | 0.0033 | 0.0127 | 0.0169 | 0.0496 | 0.0586 | 0.0939 | 0.1112 | 0.0702 | 0.0843 | 0.0915 | 0.0991 | 0.6779 | 0.6248 | 0.0000 | 0.0007 | 0.0017 | 0.0106 | 0.0439 | 0.0866 | 0.0599 | 0.0792 | 0.7175 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 683 | 505 | | 9600 | 13298 | 347.1 | 90.75 | 319.79 | 439.11 | 246 | 274 | 294 | 312 | 332 | 353 | 381 | 416 | 470 | 0.0782 | 1040 | 0.961 | 166.08 | 57.22 | 7 | 0.0454 | 436 | 0.0006 | 69.61 | 7.648 | 0.1494 | 128725.0 | 51000000 | 21600000000 | 9760000000000 | 0.4152 | 0.2290 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0044 | 0.0001 | 0.0190 | 0.0018 | 0.0789 | 0.0210 | 0.1597 | 0.0534 | 0.1464 | 0.0539 | 0.1647 | 0.0695 | 0.4253 | 0.8003 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0072 | 0.0008 | 0.0324 | 0.0123 | 0.0692 | 0.0280 | 0.0621 | 0.0217 | 0.0867 | 0.0317 | 0.7404 | 0.9055 | 0.0011 | 0.0013 | 0.0042 | 0.0116 | 0.0116 | 0.0142 | 0.0563 | 0.0927 | 0.1216 | 0.1660 | 0.1689 | 0.1789 | 0.1068 | 0.1042 | 0.1474 | 0.1416 | 0.3821 | 0.2896 | 0.0019 | 0.0036 | 0.0075 | 0.0278 | 0.0824 | 0.1264 | 0.0993 | 0.1177 | 0.5333 | 8 | 11 | 19 | 48 | 133 | 237 | 381 | 574 | 904 | 0.0562 | 65.50 | 5.773 | 0.4645 | 295068.0 | 395000000 | 660000000000 | 1.28E+15 | 0.5123 | 0.1612 | 0.0285 | 0.0008 | 0.1068 | 0.0100 | 0.2304 | 0.0455 | 0.1628 | 0.1039 | 0.1575 | 0.1882 | 0.1495 | 0.1902 | 0.0730 | 0.1302 | 0.0525 | 0.1448 | 0.0391 | 0.1865 | 0.0000 | 0.0000 | 0.0004 | 0.0007 | 0.0014 | 0.0009 | 0.0073 | 0.0049 | 0.0456 | 0.0385 | 0.0721 | 0.0610 | 0.0536 | 0.0421 | 0.0776 | 0.0731 | 0.7421 | 0.7787 | 0.0003 | 0.0009 | 0.0008 | 0.0017 | 0.0015 | 0.0020 | 0.0134 | 0.0187 | 0.0628 | 0.0715 | 0.0953 | 0.1049 | 0.0630 | 0.0729 | 0.0985 | 0.1136 | 0.6646 | 0.6137 | 0.0002 | 0.0011 | 0.0013 | 0.0095 | 0.0546 | 0.0888 | 0.0517 | 0.0893 | 0.7034 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1119 | 214 | | 5751 | 20046 | 238.3 | 49.59 | 123.21 | 136.16 | 178 | 195 | 208 | 220 | 233 | 246 | 261 | 280 | 308 | 0.0535 | 1073 | 0.956 | 183.13 | 46.27 | 1 | 0.0753 | 433 | 0.0009 | 46.08 | 7.198 | 0.1709 | 59261.6 | 15400000 | 4150000000 | 1160000000000 | 0.4175 | 0.2356 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0005 | 0.0192 | 0.0024 | 0.0653 | 0.0160 | 0.1455 | 0.0388 | 0.1466 | 0.0377 | 0.1807 | 0.0616 | 0.4387 | 0.8430 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0005 | 0.0067 | 0.0007 | 0.0275 | 0.0110 | 0.0670 | 0.0243 | 0.0630 | 0.0150 | 0.0867 | 0.0246 | 0.7466 | 0.9238 | 0.0059 | 0.0172 | 0.0109 | 0.0515 | 0.0158 | 0.1030 | 0.0732 | 0.1373 | 0.1464 | 0.2232 | 0.1771 | 0.1588 | 0.1207 | 0.0944 | 0.1563 | 0.0987 | 0.2938 | 0.1159 | 0.0023 | 0.0026 | 0.0079 | 0.0350 | 0.0801 | 0.1287 | 0.1072 | 0.1317 | 0.5045 | 9 | 12 | 16 | 32 | 68 | 116 | 169 | 230 | 320 | 0.0565 | 15.55 | 5.256 | 0.4785 | 33719.5 | 12300000 | 5330000000 | 2640000000000 | 0.4071 | 0.2119 | 0.0276 | 0.0010 | 0.1314 | 0.0064 | 0.2324 | 0.0484 | 0.2178 | 0.1001 | 0.1708 | 0.1763 | 0.1189 | 0.2178 | 0.0605 | 0.1609 | 0.0281 | 0.1323 | 0.0124 | 0.1568 | 0.0001 | 0.0000 | 0.0005 | 0.0005 | 0.0020 | 0.0009 | 0.0121 | 0.0082 | 0.0395 | 0.0341 | 0.0660 | 0.0575 | 0.0579 | 0.0452 | 0.0777 | 0.0695 | 0.7443 | 0.7842 | 0.0004 | 0.0007 | 0.0012 | 0.0015 | 0.0041 | 0.0051 | 0.0158 | 0.0229 | 0.0539 | 0.0569 | 0.0854 | 0.0956 | 0.0750 | 0.0817 | 0.1018 | 0.1010 | 0.6624 | 0.6347 | 0.0003 | 0.0013 | 0.0027 | 0.0126 | 0.0464 | 0.0749 | 0.0671 | 0.0897 | 0.7050 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 998 | 485 | | 4473 | 15868 | 223.3 | 42.57 | 170.54 | 190.66 | 167 | 185 | 199 | 211 | 221 | 232 | 244 | 259 | 279 | 0.0531 | 843 | 0.739 | 107.82 | 35.01 | 1 | 0.0722 | 323 | 0.0012 | 31.42 | 6.899 | 0.2014 | 51676.7 | 12400000 | 3060000000 | 781000000000 | 0.4192 | 0.2236 | 0.0016 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0147 | 0.0009 | 0.0482 | 0.0156 | 0.1042 | 0.0328 | 0.1130 | 0.0248 | 0.1586 | 0.0425 | 0.5557 | 0.8834 | 0.0013 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0048 | 0.0002 | 0.0213 | 0.0134 | 0.0435 | 0.0239 | 0.0437 | 0.0125 | 0.0680 | 0.0215 | 0.8155 | 0.9284 | 0.0073 | 0.0174 | 0.0132 | 0.0174 | 0.0323 | 0.0348 | 0.0852 | 0.1826 | 0.1160 | 0.1739 | 0.1880 | 0.2000 | 0.1483 | 0.1217 | 0.1219 | 0.1043 | 0.2878 | 0.1478 | 0.0018 | 0.0050 | 0.0055 | 0.0315 | 0.0721 | 0.1132 | 0.1178 | 0.1251 | 0.5279 | 12 | 17 | 28 | 49 | 86 | 143 | 221 | 333 | 461 | 0.0266 | 31.54 | 5.838 | 0.4485 | 65434.3 | 33400000 | 20100000000 | 13900000000000 | 0.5142 | 0.1765 | 0.0522 | 0.0024 | 0.1949 | 0.0152 | 0.2023 | 0.0988 | 0.1266 | 0.1475 | 0.1199 | 0.1915 | 0.1098 | 0.1664 | 0.0831 | 0.1072 | 0.0522 | 0.0954 | 0.0589 | 0.1756 | 0.0003 | 0.0004 | 0.0003 | 0.0008 | 0.0018 | 0.0008 | 0.0091 | 0.0077 | 0.0519 | 0.0426 | 0.0874 | 0.0779 | 0.0733 | 0.0632 | 0.1020 | 0.0877 | 0.6738 | 0.7190 | 0.0004 | 0.0004 | 0.0014 | 0.0034 | 0.0038 | 0.0054 | 0.0148 | 0.0199 | 0.0648 | 0.0719 | 0.1143 | 0.1171 | 0.0843 | 0.0862 | 0.1204 | 0.1209 | 0.5958 | 0.5749 | 0.0003 | 0.0012 | 0.0037 | 0.0126 | 0.0592 | 0.0980 | 0.0826 | 0.1114 | 0.6309 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 459 | 658 | | 11362 | 20851 | 286.6 | 57.22 | 160.43 | 166.77 | 216 | 238 | 254 | 268 | 283 | 297 | 315 | 335 | 362 | 0.0609 | 1269 | 1.250 | 84.58 | 36.89 | 1 | 0.0202 | 229 | 0.0006 | 69.33 | 7.619 | 0.1453 | 85435.4 | 26400000 | 8470000000 | 2810000000000 | 0.3998 | 0.2496 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0000 | 0.0151 | 0.0008 | 0.0564 | 0.0119 | 0.1324 | 0.0353 | 0.1449 | 0.0348 | 0.1680 | 0.0534 | 0.4798 | 0.8638 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0004 | 0.0244 | 0.0088 | 0.0561 | 0.0236 | 0.0596 | 0.0148 | 0.0768 | 0.0231 | 0.7756 | 0.9293 | 0.0061 | 0.0143 | 0.0094 | 0.0544 | 0.0304 | 0.0716 | 0.0839 | 0.1777 | 0.1733 | 0.2521 | 0.1926 | 0.1519 | 0.1291 | 0.0917 | 0.1512 | 0.0974 | 0.2241 | 0.0888 | 0.0015 | 0.0022 | 0.0078 | 0.0347 | 0.0806 | 0.1342 | 0.1129 | 0.1362 | 0.4899 | 14 | 18 | 28 | 51 | 95 | 156 | 222 | 299 | 405 | 0.0196 | 36.84 | 6.010 | 0.3723 | 53550.1 | 23300000 | 11800000000 | 6650000000000 | 0.5064 | 0.1481 | 0.0625 | 0.0012 | 0.2600 | 0.0157 | 0.3022 | 0.1503 | 0.1409 | 0.1993 | 0.0988 | 0.2074 | 0.0736 | 0.1703 | 0.0334 | 0.0942 | 0.0252 | 0.0818 | 0.0034 | 0.0799 | 0.0001 | 0.0000 | 0.0004 | 0.0005 | 0.0019 | 0.0015 | 0.0115 | 0.0099 | 0.0600 | 0.0532 | 0.1157 | 0.0968 | 0.0747 | 0.0636 | 0.1141 | 0.0984 | 0.6214 | 0.6761 | 0.0004 | 0.0010 | 0.0028 | 0.0037 | 0.0065 | 0.0110 | 0.0223 | 0.0260 | 0.0761 | 0.0864 | 0.1468 | 0.1528 | 0.0956 | 0.1004 | 0.1209 | 0.1293 | 0.5286 | 0.4895 | 0.0000 | 0.0010 | 0.0039 | 0.0157 | 0.0717 | 0.1279 | 0.0896 | 0.1188 | 0.5713 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 729 | 312 | | 7306 | 11974 | 613.3 | 129.28 | 138.56 | 260.97 | 460 | 513 | 546 | 576 | 604 | 631 | 663 | 705 | 779 | 0.0833 | 997 | 1.173 | 110.11 | 34.67 | 1 | 0.0356 | 260 | 0.0006 | 91.47 | 7.747 | 0.1387 | 392795.0 | 263000000 | 183000000000 | 133000000000000 | 0.4412 | 0.2054 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0084 | 0.0022 | 0.0416 | 0.0166 | 0.0910 | 0.0363 | 0.1054 | 0.0298 | 0.1371 | 0.0406 | 0.6140 | 0.8741 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0004 | 0.0024 | 0.0010 | 0.0180 | 0.0122 | 0.0418 | 0.0199 | 0.0422 | 0.0119 | 0.0634 | 0.0208 | 0.8310 | 0.9338 | 0.0046 | 0.0000 | 0.0092 | 0.0029 | 0.0295 | 0.0146 | 0.0867 | 0.1108 | 0.0941 | 0.1837 | 0.1614 | 0.2157 | 0.1144 | 0.1224 | 0.1153 | 0.1079 | 0.3847 | 0.2420 | 0.0015 | 0.0056 | 0.0082 | 0.0316 | 0.0647 | 0.1109 | 0.0989 | 0.1229 | 0.5559 | 6 | 8 | 9 | 13 | 22 | 47 | 98 | 198 | 434 | 0.0993 | 31.78 | 4.313 | 0.5808 | 87298.6 | 89300000 | 118000000000 | 185000000000000 | 0.4711 | 0.1719 | 0.0442 | 0.0014 | 0.1509 | 0.0196 | 0.2302 | 0.0825 | 0.2088 | 0.0965 | 0.1814 | 0.1972 | 0.0838 | 0.1930 | 0.0427 | 0.1343 | 0.0381 | 0.1273 | 0.0198 | 0.1483 | 0.0003 | 0.0005 | 0.0009 | 0.0005 | 0.0009 | 0.0018 | 0.0089 | 0.0096 | 0.0546 | 0.0480 | 0.1005 | 0.0828 | 0.0650 | 0.0568 | 0.0942 | 0.0835 | 0.6747 | 0.7164 | 0.0004 | 0.0004 | 0.0004 | 0.0012 | 0.0022 | 0.0008 | 0.0115 | 0.0144 | 0.0749 | 0.0804 | 0.1197 | 0.1267 | 0.0782 | 0.0776 | 0.1019 | 0.1110 | 0.6108 | 0.5875 | 0.0000 | 0.0003 | 0.0013 | 0.0127 | 0.0586 | 0.1195 | 0.0696 | 0.0917 | 0.6463 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 972 | 297 | | 4771 | 7211 | 303.5 | 65.31 | 240.93 | 226.65 | 218 | 246 | 266 | 285 | 301 | 318 | 336 | 359 | 393 | 0.1144 | 825 | 0.746 | 99.85 | 18.25 | 1 | 0.0470 | 224 | 0.0006 | 79.54 | 7.546 | 0.1380 | 96372.4 | 31900000 | 11000000000 | 3900000000000 | 0.4166 | 0.2336 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0180 | 0.0018 | 0.0709 | 0.0195 | 0.1275 | 0.0424 | 0.1468 | 0.0462 | 0.1774 | 0.0735 | 0.4551 | 0.8167 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0004 | 0.0315 | 0.0150 | 0.0601 | 0.0295 | 0.0668 | 0.0242 | 0.0840 | 0.0406 | 0.7492 | 0.8903 | 0.0069 | 0.0237 | 0.0183 | 0.0473 | 0.0171 | 0.1065 | 0.0674 | 0.1598 | 0.1063 | 0.2189 | 0.1337 | 0.1479 | 0.1029 | 0.0651 | 0.1349 | 0.0947 | 0.4126 | 0.1361 | 0.0004 | 0.0004 | 0.0056 | 0.0299 | 0.0837 | 0.1205 | 0.1008 | 0.1166 | 0.5421 | 18 | 24 | 51 | 105 | 176 | 253 | 344 | 445 | 581 | 0.0200 | 42.53 | 6.319 | 0.3498 | 109411.0 | 62100000 | 40100000000 | 28400000000000 | 0.5244 | 0.1362 | 0.0141 | 0.0041 | 0.1315 | 0.0113 | 0.1984 | 0.0504 | 0.1737 | 0.0989 | 0.2007 | 0.1819 | 0.1080 | 0.2044 | 0.0869 | 0.1380 | 0.0552 | 0.1220 | 0.0317 | 0.1890 | 0.0003 | 0.0000 | 0.0020 | 0.0008 | 0.0014 | 0.0013 | 0.0098 | 0.0072 | 0.0571 | 0.0424 | 0.0704 | 0.0721 | 0.0637 | 0.0570 | 0.0947 | 0.0816 | 0.7006 | 0.7377 | 0.0004 | 0.0005 | 0.0023 | 0.0027 | 0.0104 | 0.0068 | 0.0154 | 0.0263 | 0.0677 | 0.0693 | 0.0903 | 0.1014 | 0.0765 | 0.0928 | 0.1107 | 0.1241 | 0.6263 | 0.5761 | 0.0003 | 0.0027 | 0.0020 | 0.0140 | 0.0578 | 0.0905 | 0.0708 | 0.1002 | 0.6617 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 730 | 546 | | 7063 | 16463 | 184.9 | 40.76 | 99.35 | 87.89 | 137 | 151 | 161 | 169 | 179 | 190 | 202 | 219 | 240 | 0.0580 | 955 | 0.941 | 64.47 | 21.02 | 1 | 0.0239 | 169 | 0.0014 | 32.05 | 6.883 | 0.2025 | 35864.6 | 7300000 | 1560000000 | 348000000000 | 0.4301 | 0.2260 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0000 | 0.0175 | 0.0003 | 0.0785 | 0.0161 | 0.1523 | 0.0437 | 0.1574 | 0.0461 | 0.1936 | 0.0763 | 0.3963 | 0.8174 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0003 | 0.0317 | 0.0110 | 0.0693 | 0.0226 | 0.0664 | 0.0177 | 0.0909 | 0.0300 | 0.7338 | 0.9185 | 0.0054 | 0.0134 | 0.0069 | 0.0214 | 0.0239 | 0.0456 | 0.0677 | 0.1877 | 0.1524 | 0.2091 | 0.1963 | 0.1743 | 0.1301 | 0.1072 | 0.1617 | 0.1099 | 0.2556 | 0.1314 | 0.0009 | 0.0041 | 0.0135 | 0.0340 | 0.0810 | 0.1216 | 0.1141 | 0.1377 | 0.4931 | 13 | 22 | 36 | 53 | 73 | 98 | 131 | 169 | 224 | 0.0086 | 26.48 | 6.137 | 0.3816 | 17595.6 | 4190000 | 1210000000 | 411000000000 | 0.4596 | 0.1971 | 0.0237 | 0.0019 | 0.1194 | 0.0081 | 0.2469 | 0.0504 | 0.1843 | 0.1053 | 0.1708 | 0.1723 | 0.1252 | 0.1953 | 0.0725 | 0.1462 | 0.0367 | 0.1457 | 0.0206 | 0.1747 | 0.0004 | 0.0003 | 0.0021 | 0.0017 | 0.0031 | 0.0027 | 0.0125 | 0.0104 | 0.0556 | 0.0435 | 0.0954 | 0.0686 | 0.0762 | 0.0660 | 0.1107 | 0.0934 | 0.6440 | 0.7133 | 0.0004 | 0.0007 | 0.0015 | 0.0031 | 0.0060 | 0.0094 | 0.0218 | 0.0307 | 0.0828 | 0.1016 | 0.1359 | 0.1542 | 0.1068 | 0.1143 | 0.1359 | 0.1477 | 0.5090 | 0.4384 | 0.0005 | 0.0005 | 0.0038 | 0.0189 | 0.0670 | 0.1146 | 0.0919 | 0.1238 | 0.5791 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 726 | 600 | | 3242 | 14311 | 499.5 | 83.43 | 217.74 | 192.04 | 394 | 426 | 450 | 470 | 493 | 518 | 547 | 576 | 612 | 0.0641 | 917 | 0.675 | 101.83 | 25.18 | 1 | 0.0999 | 324 | 0.0014 | 30.06 | 6.786 | 0.2232 | 256441.0 | 135000000 | 73000000000 | 40400000000000 | 0.4615 | 0.1909 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0003 | 0.0094 | 0.0019 | 0.0476 | 0.0128 | 0.1034 | 0.0350 | 0.0932 | 0.0172 | 0.1211 | 0.0428 | 0.6215 | 0.8900 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0031 | 0.0015 | 0.0241 | 0.0115 | 0.0544 | 0.0319 | 0.0457 | 0.0124 | 0.0582 | 0.0254 | 0.8139 | 0.9170 | 0.0069 | 0.2000 | 0.0185 | 0.2000 | 0.0254 | 0.1333 | 0.0762 | 0.2667 | 0.1224 | 0.0667 | 0.2517 | 0.1333 | 0.1201 | 0.0000 | 0.1386 | 0.0000 | 0.2402 | 0.0000 | 0.0026 | 0.0013 | 0.0110 | 0.0272 | 0.0725 | 0.1146 | 0.0881 | 0.1075 | 0.5751 | 27 | 59 | 91 | 117 | 149 | 197 | 277 | 373 | 502 | 0.0056 | 39.72 | 6.385 | 0.3525 | 84287.2 | 43400000 | 26300000000 | 17700000000000 | 0.5008 | 0.1648 | 0.0367 | 0.0032 | 0.1371 | 0.0092 | 0.2234 | 0.0566 | 0.1856 | 0.1095 | 0.1607 | 0.1802 | 0.1201 | 0.1909 | 0.0615 | 0.1404 | 0.0434 | 0.1268 | 0.0316 | 0.1831 | 0.0010 | 0.0008 | 0.0021 | 0.0015 | 0.0046 | 0.0040 | 0.0193 | 0.0143 | 0.0618 | 0.0534 | 0.0900 | 0.0837 | 0.0683 | 0.0638 | 0.1015 | 0.0908 | 0.6515 | 0.6878 | 0.0004 | 0.0008 | 0.0007 | 0.0042 | 0.0048 | 0.0124 | 0.0253 | 0.0287 | 0.0830 | 0.0944 | 0.1247 | 0.1404 | 0.1000 | 0.1138 | 0.1419 | 0.1548 | 0.5192 | 0.4506 | 0.0006 | 0.0023 | 0.0015 | 0.0250 | 0.0581 | 0.1139 | 0.0806 | 0.1154 | 0.6027 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 198 | 613 | | 10703 | 25098 | 480.9 | 117.51 | 176.04 | 229.83 | 340 | 382 | 416 | 442 | 466 | 492 | 523 | 565 | 635 | 0.0451 | 1133 | 1.039 | 108.30 | 27.31 | 1 | 0.0238 | 255 | 0.0012 | 25.67 | 7.037 | 0.2548 | 245102.0 | 133000000 | 76300000000 | 46700000000000 | 0.4289 | 0.2132 | 0.0002 | 0.0001 | 0.0017 | 0.0003 | 0.0032 | 0.0004 | 0.0125 | 0.0023 | 0.0362 | 0.0148 | 0.0705 | 0.0249 | 0.0739 | 0.0234 | 0.1025 | 0.0348 | 0.6994 | 0.8989 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0013 | 0.0000 | 0.0040 | 0.0009 | 0.0147 | 0.0099 | 0.0296 | 0.0144 | 0.0296 | 0.0114 | 0.0431 | 0.0165 | 0.8765 | 0.9467 | 0.0027 | 0.0042 | 0.0037 | 0.0125 | 0.0197 | 0.0111 | 0.0256 | 0.0376 | 0.0809 | 0.0794 | 0.0969 | 0.1059 | 0.0793 | 0.0975 | 0.1145 | 0.1170 | 0.5767 | 0.5348 | 0.0011 | 0.0046 | 0.0057 | 0.0221 | 0.0472 | 0.0715 | 0.0723 | 0.0974 | 0.6780 | 8 | 11 | 18 | 43 | 88 | 143 | 209 | 306 | 470 | 0.0340 | 59.76 | 6.000 | 0.4097 | 83807.8 | 61300000 | 58300000000 | 65200000000000 | 0.4708 | 0.1676 | 0.0402 | 0.0013 | 0.1379 | 0.0145 | 0.2575 | 0.0830 | 0.1639 | 0.1217 | 0.1467 | 0.1865 | 0.1105 | 0.1891 | 0.0710 | 0.1300 | 0.0457 | 0.1206 | 0.0267 | 0.1533 | 0.0004 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0011 | 0.0127 | 0.0082 | 0.0586 | 0.0466 | 0.0992 | 0.0851 | 0.0724 | 0.0582 | 0.1097 | 0.0882 | 0.6453 | 0.7122 | 0.0004 | 0.0016 | 0.0013 | 0.0016 | 0.0047 | 0.0061 | 0.0204 | 0.0261 | 0.0847 | 0.0889 | 0.1296 | 0.1451 | 0.0831 | 0.0884 | 0.1286 | 0.1255 | 0.5472 | 0.5169 | 0.0007 | 0.0010 | 0.0037 | 0.0134 | 0.0728 | 0.1205 | 0.0761 | 0.1192 | 0.5926 | ||
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1271 | 351 | | 4157 | 9898 | 475.9 | 89.44 | 163.26 | 251.77 | 360 | 394 | 423 | 449 | 475 | 498 | 524 | 554 | 594 | 0.0813 | 805 | 1.028 | 152.20 | 40.79 | 2 | 0.0871 | 362 | 0.0008 | 73.60 | 7.318 | 0.1483 | 234454.0 | 119000000 | 62600000000 | 33700000000000 | 0.4174 | 0.2233 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0017 | 0.0000 | 0.0196 | 0.0010 | 0.0716 | 0.0187 | 0.1191 | 0.0382 | 0.1160 | 0.0296 | 0.1725 | 0.0500 | 0.4981 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0069 | 0.0007 | 0.0343 | 0.0162 | 0.0480 | 0.0300 | 0.0474 | 0.0157 | 0.0809 | 0.0288 | 0.7811 | 0.9086 | 0.0000 | 0.0390 | 0.0204 | 0.0260 | 0.0471 | 0.1429 | 0.0973 | 0.2597 | 0.1476 | 0.2338 | 0.2057 | 0.1558 | 0.1350 | 0.0779 | 0.1162 | 0.0519 | 0.2308 | 0.0130 | 0.0010 | 0.0010 | 0.0048 | 0.0299 | 0.0676 | 0.1356 | 0.1236 | 0.1472 | 0.4894 | 7 | 10 | 13 | 22 | 39 | 75 | 136 | 293 | 547 | 0.0676 | 32.18 | 4.895 | 0.5343 | 90034.8 | 69000000 | 62100000000 | 62700000000000 | 0.5861 | 0.0893 | 0.0409 | 0.0025 | 0.1595 | 0.0187 | 0.2704 | 0.0934 | 0.2179 | 0.1214 | 0.1595 | 0.1766 | 0.0914 | 0.2054 | 0.0311 | 0.1350 | 0.0214 | 0.1180 | 0.0078 | 0.1290 | 0.0003 | 0.0003 | 0.0013 | 0.0017 | 0.0043 | 0.0049 | 0.0140 | 0.0129 | 0.0478 | 0.0466 | 0.0870 | 0.0765 | 0.0558 | 0.0552 | 0.0797 | 0.0797 | 0.7096 | 0.7222 | 0.0004 | 0.0000 | 0.0016 | 0.0017 | 0.0028 | 0.0043 | 0.0172 | 0.0170 | 0.0537 | 0.0679 | 0.1034 | 0.0909 | 0.0577 | 0.0635 | 0.0885 | 0.0905 | 0.6747 | 0.6642 | 0.0000 | 0.0026 | 0.0026 | 0.0125 | 0.0521 | 0.0922 | 0.0558 | 0.0845 | 0.6978 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 655 | 519 | | 12431 | 24620 | 390.0 | 70.08 | 73.02 | 145.52 | 287 | 322 | 350 | 376 | 398 | 418 | 437 | 454 | 476 | 0.0531 | 1307 | 0.717 | 116.71 | 35.11 | 3 | 0.0323 | 401 | 0.0014 | 13.24 | 6.814 | 0.3028 | 157023.0 | 65000000 | 27500000000 | 11900000000000 | 0.4378 | 0.1981 | 0.0007 | 0.0000 | 0.0029 | 0.0000 | 0.0055 | 0.0000 | 0.0115 | 0.0009 | 0.0276 | 0.0098 | 0.0447 | 0.0175 | 0.0492 | 0.0111 | 0.0732 | 0.0171 | 0.7847 | 0.9436 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0000 | 0.0037 | 0.0009 | 0.0122 | 0.0098 | 0.0195 | 0.0175 | 0.0178 | 0.0105 | 0.0271 | 0.0152 | 0.9168 | 0.9461 | 0.0102 | 1.0000 | 0.0215 | 0.0000 | 0.0269 | 0.0000 | 0.0449 | 0.0000 | 0.0682 | 0.0000 | 0.0922 | 0.0000 | 0.0999 | 0.0000 | 0.1191 | 0.0000 | 0.5171 | 0.0000 | 0.0007 | 0.0036 | 0.0042 | 0.0104 | 0.0227 | 0.0348 | 0.0407 | 0.0547 | 0.8282 | 8 | 10 | 11 | 13 | 15 | 20 | 33 | 82 | 218 | 0.1379 | 2.58 | 2.741 | 0.6004 | 26508.4 | 16200000 | 12600000000 | 11400000000000 | 0.6289 | 0.0769 | 0.0413 | 0.0027 | 0.1013 | 0.0182 | 0.1888 | 0.0633 | 0.1750 | 0.0919 | 0.1721 | 0.1461 | 0.1327 | 0.1875 | 0.1013 | 0.1379 | 0.0560 | 0.1347 | 0.0315 | 0.2176 | 0.0002 | 0.0005 | 0.0007 | 0.0006 | 0.0016 | 0.0015 | 0.0123 | 0.0101 | 0.0446 | 0.0428 | 0.0768 | 0.0683 | 0.0519 | 0.0466 | 0.0718 | 0.0703 | 0.7402 | 0.7592 | 0.0004 | 0.0009 | 0.0008 | 0.0018 | 0.0023 | 0.0018 | 0.0159 | 0.0140 | 0.0529 | 0.0605 | 0.0898 | 0.0918 | 0.0567 | 0.0628 | 0.0814 | 0.0868 | 0.6997 | 0.6794 | 0.0004 | 0.0000 | 0.0015 | 0.0114 | 0.0529 | 0.0806 | 0.0550 | 0.0825 | 0.7157 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 758 | 289 | | 9172 | 25842 | 480.5 | 106.34 | 78.95 | 164.92 | 348 | 401 | 442 | 475 | 501 | 523 | 545 | 566 | 596 | 0.0441 | 1140 | 0.391 | 100.72 | 18.03 | 8 | 0.0345 | 316 | 0.0008 | 40.91 | 7.452 | 0.2087 | 242144.0 | 126000000 | 66900000000 | 36300000000000 | 0.4467 | 0.2018 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0040 | 0.0000 | 0.0106 | 0.0006 | 0.0423 | 0.0150 | 0.0713 | 0.0262 | 0.0664 | 0.0166 | 0.1037 | 0.0291 | 0.6983 | 0.9124 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0017 | 0.0006 | 0.0200 | 0.0146 | 0.0359 | 0.0255 | 0.0241 | 0.0145 | 0.0416 | 0.0249 | 0.8754 | 0.9198 | 0.0060 | 0.0000 | 0.0172 | 0.0000 | 0.0139 | 0.0000 | 0.0404 | 0.0000 | 0.0841 | 0.0000 | 0.0986 | 0.0000 | 0.1138 | 0.0000 | 0.1456 | 0.0000 | 0.4805 | 0.0000 | 0.0004 | 0.0006 | 0.0024 | 0.0101 | 0.0324 | 0.0533 | 0.0494 | 0.0684 | 0.7831 | 9 | 11 | 12 | 14 | 17 | 24 | 40 | 89 | 218 | 0.1598 | 4.29 | 2.873 | 0.6588 | 33429.4 | 26600000 | 27600000000 | 33200000000000 | 0.5581 | 0.1027 | 0.0519 | 0.0043 | 0.1247 | 0.0179 | 0.1628 | 0.0737 | 0.1498 | 0.1096 | 0.1498 | 0.1412 | 0.1264 | 0.1537 | 0.0840 | 0.1174 | 0.0693 | 0.1232 | 0.0814 | 0.2590 | 0.0005 | 0.0006 | 0.0015 | 0.0017 | 0.0029 | 0.0034 | 0.0099 | 0.0097 | 0.0423 | 0.0371 | 0.0707 | 0.0584 | 0.0431 | 0.0425 | 0.0693 | 0.0689 | 0.7598 | 0.7777 | 0.0004 | 0.0002 | 0.0008 | 0.0000 | 0.0014 | 0.0044 | 0.0124 | 0.0143 | 0.0545 | 0.0581 | 0.0798 | 0.0856 | 0.0569 | 0.0579 | 0.0862 | 0.0954 | 0.7076 | 0.6841 | 0.0005 | 0.0016 | 0.0031 | 0.0104 | 0.0474 | 0.0722 | 0.0478 | 0.0770 | 0.7400 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 465 | 620 | | 9047 | 14449 | 390.5 | 71.92 | 168.72 | 172.88 | 299 | 329 | 350 | 370 | 388 | 407 | 428 | 452 | 486 | 0.0895 | 1293 | 1.076 | 123.98 | 51.35 | 1 | 0.0385 | 348 | 0.0005 | 92.93 | 7.898 | 0.1210 | 157668.0 | 65700000 | 28200000000 | 12400000000000 | 0.4145 | 0.2342 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0022 | 0.0002 | 0.0141 | 0.0007 | 0.0465 | 0.0115 | 0.1136 | 0.0295 | 0.1207 | 0.0268 | 0.1565 | 0.0404 | 0.5462 | 0.8909 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0010 | 0.0002 | 0.0046 | 0.0002 | 0.0237 | 0.0104 | 0.0542 | 0.0226 | 0.0542 | 0.0139 | 0.0680 | 0.0208 | 0.7940 | 0.9319 | 0.0116 | 0.0192 | 0.0085 | 0.0513 | 0.0263 | 0.1346 | 0.0819 | 0.1795 | 0.1560 | 0.2628 | 0.1745 | 0.1410 | 0.1228 | 0.0769 | 0.1475 | 0.1026 | 0.2710 | 0.0321 | 0.0007 | 0.0018 | 0.0052 | 0.0335 | 0.0767 | 0.1181 | 0.1018 | 0.1243 | 0.5379 | 18 | 23 | 34 | 60 | 103 | 161 | 227 | 307 | 422 | 0.0185 | 43.16 | 6.177 | 0.3683 | 58352.5 | 26900000 | 14800000000 | 9200000000000 | 0.6196 | 0.0820 | 0.0780 | 0.0010 | 0.2479 | 0.0209 | 0.2643 | 0.1364 | 0.1377 | 0.1919 | 0.1220 | 0.2022 | 0.0833 | 0.1816 | 0.0348 | 0.1065 | 0.0236 | 0.0841 | 0.0085 | 0.0754 | 0.0002 | 0.0003 | 0.0011 | 0.0008 | 0.0038 | 0.0025 | 0.0145 | 0.0128 | 0.0768 | 0.0638 | 0.1137 | 0.1016 | 0.0820 | 0.0741 | 0.1214 | 0.1071 | 0.5866 | 0.6370 | 0.0004 | 0.0005 | 0.0019 | 0.0034 | 0.0064 | 0.0118 | 0.0293 | 0.0359 | 0.0981 | 0.1148 | 0.1436 | 0.1489 | 0.0967 | 0.1052 | 0.1272 | 0.1358 | 0.4964 | 0.4437 | 0.0004 | 0.0018 | 0.0034 | 0.0211 | 0.0839 | 0.1343 | 0.0921 | 0.1248 | 0.5384 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1186 | 399 | | 7576 | 21944 | 290.6 | 51.00 | 184.64 | 218.05 | 227 | 248 | 263 | 275 | 288 | 301 | 316 | 333 | 359 | 0.0463 | 1015 | 1.252 | 130.06 | 51.55 | 1 | 0.0429 | 325 | 0.0008 | 52.05 | 7.382 | 0.1525 | 87051.1 | 26800000 | 8500000000 | 2760000000000 | 0.4494 | 0.2025 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0025 | 0.0000 | 0.0115 | 0.0007 | 0.0438 | 0.0130 | 0.1032 | 0.0258 | 0.1170 | 0.0248 | 0.1591 | 0.0387 | 0.5622 | 0.8970 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0054 | 0.0005 | 0.0213 | 0.0107 | 0.0519 | 0.0209 | 0.0498 | 0.0152 | 0.0734 | 0.0201 | 0.7964 | 0.9326 | 0.0071 | 0.0446 | 0.0162 | 0.0804 | 0.0396 | 0.1339 | 0.0974 | 0.1429 | 0.1511 | 0.1696 | 0.1785 | 0.1964 | 0.1247 | 0.0893 | 0.1400 | 0.0804 | 0.2454 | 0.0625 | 0.0011 | 0.0033 | 0.0096 | 0.0325 | 0.0771 | 0.1263 | 0.1151 | 0.1403 | 0.4947 | 12 | 15 | 19 | 33 | 78 | 152 | 249 | 366 | 521 | 0.0296 | 46.67 | 5.933 | 0.4162 | 81634.4 | 47000000 | 31600000000 | 23900000000000 | 0.4913 | 0.1440 | 0.0391 | 0.0020 | 0.1582 | 0.0154 | 0.2635 | 0.0835 | 0.1628 | 0.1494 | 0.1571 | 0.1988 | 0.1185 | 0.1822 | 0.0575 | 0.1124 | 0.0276 | 0.1077 | 0.0155 | 0.1486 | 0.0003 | 0.0002 | 0.0004 | 0.0007 | 0.0030 | 0.0010 | 0.0080 | 0.0073 | 0.0456 | 0.0397 | 0.0771 | 0.0667 | 0.0544 | 0.0443 | 0.0810 | 0.0710 | 0.7301 | 0.7690 | 0.0004 | 0.0003 | 0.0014 | 0.0011 | 0.0050 | 0.0044 | 0.0109 | 0.0177 | 0.0535 | 0.0620 | 0.1030 | 0.1046 | 0.0676 | 0.0770 | 0.0949 | 0.1153 | 0.6633 | 0.6176 | 0.0005 | 0.0014 | 0.0029 | 0.0115 | 0.0492 | 0.0817 | 0.0614 | 0.0892 | 0.7022 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1251 | 480 | | 6017 | 19160 | 372.6 | 81.16 | 69.86 | 92.27 | 278 | 301 | 322 | 342 | 361 | 382 | 404 | 437 | 483 | 0.0573 | 1098 | 1.122 | 78.10 | 30.02 | 1 | 0.0346 | 208 | 0.0012 | 27.16 | 6.956 | 0.2116 | 145447.0 | 59500000 | 25500000000 | 11400000000000 | 0.4095 | 0.2372 | 0.0010 | 0.0000 | 0.0018 | 0.0002 | 0.0054 | 0.0002 | 0.0137 | 0.0014 | 0.0485 | 0.0173 | 0.0996 | 0.0335 | 0.1201 | 0.0274 | 0.1504 | 0.0393 | 0.5594 | 0.8807 | 0.0008 | 0.0000 | 0.0010 | 0.0000 | 0.0018 | 0.0000 | 0.0071 | 0.0002 | 0.0212 | 0.0113 | 0.0414 | 0.0210 | 0.0549 | 0.0125 | 0.0676 | 0.0208 | 0.8040 | 0.9343 | 0.0038 | 0.0028 | 0.0086 | 0.0111 | 0.0250 | 0.0111 | 0.0547 | 0.0474 | 0.0960 | 0.1393 | 0.1353 | 0.1309 | 0.0988 | 0.0919 | 0.1180 | 0.1727 | 0.4597 | 0.3928 | 0.0011 | 0.0007 | 0.0108 | 0.0310 | 0.0601 | 0.1045 | 0.0952 | 0.1153 | 0.5812 | 6 | 8 | 10 | 14 | 25 | 44 | 75 | 126 | 201 | 0.0798 | 9.76 | 4.599 | 0.5642 | 13394.3 | 3680000 | 1220000000 | 456000000000 | 0.4787 | 0.1430 | 0.0265 | 0.0016 | 0.1013 | 0.0063 | 0.2053 | 0.0393 | 0.1849 | 0.0976 | 0.1931 | 0.1897 | 0.1292 | 0.1970 | 0.0802 | 0.1581 | 0.0578 | 0.1362 | 0.0218 | 0.1742 | 0.0009 | 0.0003 | 0.0015 | 0.0010 | 0.0025 | 0.0039 | 0.0136 | 0.0110 | 0.0410 | 0.0369 | 0.0620 | 0.0559 | 0.0496 | 0.0499 | 0.0745 | 0.0671 | 0.7545 | 0.7740 | 0.0004 | 0.0013 | 0.0013 | 0.0013 | 0.0026 | 0.0023 | 0.0149 | 0.0153 | 0.0444 | 0.0503 | 0.0766 | 0.0916 | 0.0638 | 0.0652 | 0.0850 | 0.0913 | 0.7110 | 0.6815 | 0.0005 | 0.0017 | 0.0028 | 0.0150 | 0.0394 | 0.0700 | 0.0556 | 0.0763 | 0.7387 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 367 | 527 | | 14166 | 30978 | 166.3 | 51.48 | 150.74 | 180.13 | 108 | 123 | 136 | 147 | 158 | 171 | 186 | 207 | 241 | 0.0455 | 1410 | 1.186 | 107.56 | 39.85 | 4 | 0.0193 | 274 | 0.0029 | 11.78 | 6.212 | 0.3232 | 30318.4 | 6020000 | 1290000000 | 298000000000 | 0.4567 | 0.2012 | 0.0010 | 0.0002 | 0.0020 | 0.0003 | 0.0095 | 0.0011 | 0.0293 | 0.0063 | 0.0939 | 0.0301 | 0.1627 | 0.0648 | 0.1523 | 0.0591 | 0.1747 | 0.0901 | 0.3747 | 0.7480 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0027 | 0.0002 | 0.0099 | 0.0021 | 0.0378 | 0.0155 | 0.0638 | 0.0296 | 0.0626 | 0.0267 | 0.0911 | 0.0439 | 0.7313 | 0.8820 | 0.0021 | 0.0018 | 0.0049 | 0.0083 | 0.0147 | 0.0155 | 0.0350 | 0.0596 | 0.0936 | 0.1173 | 0.1393 | 0.1757 | 0.0967 | 0.1203 | 0.1362 | 0.1471 | 0.4774 | 0.3544 | 0.0008 | 0.0034 | 0.0088 | 0.0319 | 0.0709 | 0.1074 | 0.0856 | 0.1046 | 0.5866 | 8 | 10 | 15 | 33 | 75 | 129 | 195 | 283 | 413 | 0.0651 | 14.33 | 5.012 | 0.4997 | 55169.9 | 27400000 | 16300000000 | 11100000000000 | 0.5068 | 0.1638 | 0.0376 | 0.0026 | 0.1800 | 0.0101 | 0.2471 | 0.0930 | 0.1592 | 0.1413 | 0.1404 | 0.1940 | 0.1108 | 0.1938 | 0.0625 | 0.1310 | 0.0393 | 0.1131 | 0.0232 | 0.1211 | 0.0002 | 0.0002 | 0.0005 | 0.0001 | 0.0016 | 0.0012 | 0.0097 | 0.0069 | 0.0522 | 0.0426 | 0.0886 | 0.0730 | 0.0686 | 0.0557 | 0.1054 | 0.0879 | 0.6732 | 0.7326 | 0.0004 | 0.0006 | 0.0015 | 0.0020 | 0.0027 | 0.0051 | 0.0177 | 0.0220 | 0.0740 | 0.0904 | 0.1206 | 0.1278 | 0.0882 | 0.0952 | 0.1271 | 0.1330 | 0.5678 | 0.5239 | 0.0000 | 0.0020 | 0.0028 | 0.0144 | 0.0620 | 0.1077 | 0.0815 | 0.1152 | 0.6146 |