High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 945 | 791 | | 7136 | 8653 | 396.4 | 68.86 | 331.09 | 487.17 | 292 | 338 | 365 | 386 | 406 | 423 | 439 | 454 | 478 | 0.0953 | 825 | 1.046 | 109.66 | 38.48 | 6 | 0.0419 | 299 | 0.0024 | 9.08 | 6.362 | 0.3660 | 161888.0 | 67800000 | 29000000000 | 12700000000000 | 0.4181 | 0.2153 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0000 | 0.0079 | 0.0011 | 0.0218 | 0.0106 | 0.0533 | 0.0271 | 0.0385 | 0.0132 | 0.0585 | 0.0186 | 0.8142 | 0.9294 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0011 | 0.0113 | 0.0105 | 0.0289 | 0.0260 | 0.0141 | 0.0119 | 0.0204 | 0.0173 | 0.9222 | 0.9333 | 0.0066 | 0.0000 | 0.0066 | 0.0000 | 0.0263 | 0.0000 | 0.0447 | 0.0000 | 0.1092 | 0.0000 | 0.1184 | 0.0000 | 0.1158 | 0.0000 | 0.1382 | 0.0000 | 0.4342 | 0.0000 | 0.0005 | 0.0015 | 0.0051 | 0.0101 | 0.0281 | 0.0398 | 0.0367 | 0.0529 | 0.8252 | 10 | 12 | 15 | 26 | 85 | 211 | 381 | 631 | 998 | 0.1055 | 26.80 | 5.014 | 0.5502 | 346927.0 | 541000000 | 1110000000000 | 2.77E+15 | 0.4761 | 0.1685 | 0.0161 | 0.0031 | 0.0966 | 0.0086 | 0.1804 | 0.0350 | 0.1739 | 0.0871 | 0.1643 | 0.1540 | 0.1433 | 0.1882 | 0.0934 | 0.1407 | 0.0805 | 0.1198 | 0.0515 | 0.2636 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0025 | 0.0017 | 0.0063 | 0.0068 | 0.0348 | 0.0256 | 0.0659 | 0.0501 | 0.0446 | 0.0400 | 0.0681 | 0.0535 | 0.7768 | 0.8202 | 0.0000 | 0.0004 | 0.0004 | 0.0018 | 0.0039 | 0.0049 | 0.0102 | 0.0123 | 0.0481 | 0.0511 | 0.0777 | 0.0886 | 0.0560 | 0.0675 | 0.0765 | 0.0825 | 0.7272 | 0.6909 | 0.0000 | 0.0004 | 0.0036 | 0.0093 | 0.0411 | 0.0750 | 0.0496 | 0.0650 | 0.7562 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 274 | 724 | | 833 | 13982 | 37.7 | 9.22 | 181.15 | 216.84 | 28 | 30 | 32 | 34 | 36 | 38 | 40 | 44 | 50 | 0.0473 | 662 | 1.199 | 23.54 | 8.94 | 3 | 0.0732 | 61 | 0.0229 | 2.86 | 4.160 | 0.4919 | 1505.4 | 64089 | 2920000 | 142000000 | 0.4024 | 0.2135 | 0.0039 | 0.0000 | 0.0197 | 0.0000 | 0.0197 | 0.0000 | 0.0907 | 0.0156 | 0.1243 | 0.0650 | 0.1460 | 0.0728 | 0.1913 | 0.1027 | 0.2012 | 0.1352 | 0.2032 | 0.6086 | 0.0031 | 0.0000 | 0.0108 | 0.0000 | 0.0154 | 0.0000 | 0.0555 | 0.0132 | 0.0709 | 0.0505 | 0.0755 | 0.0457 | 0.1248 | 0.0721 | 0.1171 | 0.0805 | 0.5270 | 0.7380 | 0.0141 | 0.0317 | 0.0070 | 0.0317 | 0.0211 | 0.0317 | 0.0845 | 0.0794 | 0.1268 | 0.1746 | 0.1479 | 0.1587 | 0.0775 | 0.1429 | 0.1831 | 0.1111 | 0.3380 | 0.2381 | 0.0089 | 0.0417 | 0.0357 | 0.0774 | 0.0923 | 0.1220 | 0.1042 | 0.1399 | 0.3780 | 13 | 15 | 18 | 25 | 72 | 155 | 247 | 356 | 505 | 0.1047 | 25.13 | 4.988 | 0.5234 | 79833.1 | 46100000 | 31400000000 | 24300000000000 | 0.5786 | 0.1133 | 0.0295 | 0.0009 | 0.1412 | 0.0151 | 0.2513 | 0.0722 | 0.1854 | 0.1324 | 0.1750 | 0.2019 | 0.1161 | 0.2027 | 0.0537 | 0.1479 | 0.0286 | 0.1209 | 0.0191 | 0.1062 | 0.0005 | 0.0000 | 0.0021 | 0.0008 | 0.0031 | 0.0022 | 0.0102 | 0.0085 | 0.0401 | 0.0383 | 0.0610 | 0.0504 | 0.0571 | 0.0510 | 0.0875 | 0.0745 | 0.7384 | 0.7744 | 0.0004 | 0.0002 | 0.0013 | 0.0015 | 0.0054 | 0.0051 | 0.0173 | 0.0245 | 0.0542 | 0.0646 | 0.0886 | 0.0970 | 0.0864 | 0.1030 | 0.1156 | 0.1191 | 0.6309 | 0.5849 | 0.0004 | 0.0035 | 0.0025 | 0.0146 | 0.0434 | 0.0766 | 0.0726 | 0.0991 | 0.6873 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 461 | 123 | | 3257 | 6809 | 514.7 | 105.53 | 61.25 | 124.20 | 368 | 433 | 474 | 500 | 525 | 551 | 579 | 608 | 638 | 0.0824 | 561 | 0.766 | 87.00 | 16.03 | 3 | 0.0620 | 202 | 0.0010 | 52.75 | 7.148 | 0.1825 | 276060.0 | 153000000 | 86800000000 | 50400000000000 | 0.4286 | 0.2196 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0068 | 0.0000 | 0.0140 | 0.0013 | 0.0512 | 0.0198 | 0.0978 | 0.0406 | 0.0965 | 0.0227 | 0.1277 | 0.0373 | 0.6046 | 0.8782 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0029 | 0.0013 | 0.0220 | 0.0197 | 0.0447 | 0.0384 | 0.0293 | 0.0184 | 0.0411 | 0.0288 | 0.8596 | 0.8934 | 0.0077 | 0.1333 | 0.0173 | 0.1333 | 0.0288 | 0.0667 | 0.0865 | 0.1333 | 0.1404 | 0.2667 | 0.1442 | 0.1333 | 0.1231 | 0.0000 | 0.1654 | 0.1333 | 0.2865 | 0.0000 | 0.0011 | 0.0023 | 0.0079 | 0.0186 | 0.0514 | 0.0814 | 0.0729 | 0.1040 | 0.6605 | 7 | 9 | 11 | 12 | 14 | 19 | 31 | 56 | 175 | 0.1883 | 7.43 | 3.201 | 0.7374 | 19174.6 | 10600000 | 7360000000 | 5780000000000 | 0.4921 | 0.1647 | 0.0338 | 0.0142 | 0.0549 | 0.0252 | 0.0717 | 0.0377 | 0.0928 | 0.0660 | 0.1392 | 0.0849 | 0.1814 | 0.1289 | 0.2363 | 0.1321 | 0.1097 | 0.1525 | 0.0802 | 0.3585 | 0.0034 | 0.0045 | 0.0048 | 0.0078 | 0.0034 | 0.0111 | 0.0109 | 0.0167 | 0.0212 | 0.0279 | 0.0519 | 0.0507 | 0.0355 | 0.0423 | 0.0444 | 0.0591 | 0.8245 | 0.7799 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0073 | 0.0078 | 0.0334 | 0.0336 | 0.0465 | 0.0509 | 0.0302 | 0.0259 | 0.0522 | 0.0578 | 0.8280 | 0.8240 | 0.0008 | 0.0008 | 0.0046 | 0.0106 | 0.0236 | 0.0540 | 0.0274 | 0.0547 | 0.8237 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 296 | 572 | | 8086 | 26684 | 302.2 | 79.97 | 205.86 | 280.95 | 205 | 239 | 262 | 283 | 304 | 326 | 349 | 373 | 401 | 0.0475 | 1267 | 0.665 | 59.68 | 11.31 | 3 | 0.0177 | 143 | 0.0008 | 40.70 | 7.343 | 0.1978 | 97719.6 | 33200000 | 11800000000 | 4310000000000 | 0.3795 | 0.2472 | 0.0011 | 0.0000 | 0.0016 | 0.0000 | 0.0074 | 0.0003 | 0.0207 | 0.0023 | 0.0767 | 0.0172 | 0.1294 | 0.0437 | 0.1280 | 0.0397 | 0.1701 | 0.0578 | 0.4650 | 0.8391 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0016 | 0.0000 | 0.0058 | 0.0012 | 0.0212 | 0.0116 | 0.0426 | 0.0234 | 0.0420 | 0.0137 | 0.0672 | 0.0206 | 0.8188 | 0.9295 | 0.0020 | 0.0068 | 0.0051 | 0.0228 | 0.0164 | 0.0387 | 0.0475 | 0.1048 | 0.0915 | 0.2096 | 0.1539 | 0.1891 | 0.1099 | 0.1071 | 0.1595 | 0.1344 | 0.4141 | 0.1868 | 0.0002 | 0.0041 | 0.0090 | 0.0124 | 0.0506 | 0.0812 | 0.0669 | 0.0846 | 0.6910 | 12 | 15 | 18 | 23 | 51 | 133 | 250 | 395 | 618 | 0.1321 | 29.66 | 4.846 | 0.5609 | 121307.0 | 98300000 | 95600000000 | 106000000000000 | 0.3068 | 0.3447 | 0.0442 | 0.0016 | 0.1546 | 0.0133 | 0.2155 | 0.0891 | 0.1482 | 0.1397 | 0.1751 | 0.1708 | 0.1401 | 0.1937 | 0.0636 | 0.1158 | 0.0442 | 0.1223 | 0.0145 | 0.1536 | 0.0006 | 0.0000 | 0.0012 | 0.0004 | 0.0031 | 0.0022 | 0.0115 | 0.0116 | 0.0386 | 0.0343 | 0.0571 | 0.0510 | 0.0451 | 0.0319 | 0.0658 | 0.0520 | 0.7769 | 0.8165 | 0.0007 | 0.0010 | 0.0026 | 0.0022 | 0.0043 | 0.0052 | 0.0155 | 0.0182 | 0.0500 | 0.0581 | 0.0812 | 0.0876 | 0.0644 | 0.0690 | 0.0894 | 0.1000 | 0.6918 | 0.6586 | 0.0002 | 0.0011 | 0.0040 | 0.0169 | 0.0395 | 0.0700 | 0.0579 | 0.0782 | 0.7322 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 173 | 580 | | 3314 | 11955 | 517.2 | 91.88 | 119.57 | 243.85 | 373 | 433 | 487 | 512 | 531 | 550 | 573 | 598 | 624 | 0.0613 | 733 | 0.446 | 104.39 | 23.32 | 3 | 0.0993 | 329 | 0.0010 | 41.90 | 7.124 | 0.2030 | 275939.0 | 151000000 | 84400000000 | 48000000000000 | 0.4375 | 0.1965 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0017 | 0.0003 | 0.0071 | 0.0009 | 0.0384 | 0.0163 | 0.0744 | 0.0359 | 0.0660 | 0.0157 | 0.0994 | 0.0273 | 0.7101 | 0.9033 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0000 | 0.0003 | 0.0014 | 0.0009 | 0.0206 | 0.0163 | 0.0343 | 0.0359 | 0.0220 | 0.0157 | 0.0354 | 0.0273 | 0.8851 | 0.9033 | 0.0134 | 0.0000 | 0.0160 | 0.0000 | 0.0428 | 0.0000 | 0.0856 | 0.0000 | 0.1096 | 0.0000 | 0.1791 | 0.0000 | 0.1123 | 0.0000 | 0.1417 | 0.0000 | 0.2995 | 0.0000 | 0.0005 | 0.0042 | 0.0094 | 0.0141 | 0.0381 | 0.0522 | 0.0637 | 0.0914 | 0.7262 | 9 | 12 | 14 | 16 | 21 | 31 | 57 | 130 | 371 | 0.1465 | 4.98 | 3.299 | 0.6421 | 73753.8 | 72700000 | 87000000000 | 116000000000000 | 0.4905 | 0.1557 | 0.0398 | 0.0000 | 0.1155 | 0.0121 | 0.1474 | 0.0864 | 0.1932 | 0.1021 | 0.1972 | 0.1690 | 0.1554 | 0.1820 | 0.0777 | 0.1328 | 0.0498 | 0.1235 | 0.0239 | 0.1922 | 0.0000 | 0.0000 | 0.0025 | 0.0012 | 0.0051 | 0.0044 | 0.0108 | 0.0097 | 0.0375 | 0.0400 | 0.0563 | 0.0512 | 0.0512 | 0.0465 | 0.0776 | 0.0787 | 0.7589 | 0.7684 | 0.0000 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0028 | 0.0119 | 0.0127 | 0.0419 | 0.0409 | 0.0608 | 0.0682 | 0.0591 | 0.0564 | 0.0784 | 0.0804 | 0.7466 | 0.7377 | 0.0008 | 0.0008 | 0.0028 | 0.0097 | 0.0399 | 0.0565 | 0.0480 | 0.0871 | 0.7543 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1053 | 104 | | 2330 | 7315 | 404.0 | 189.76 | 84.83 | 144.30 | 168 | 214 | 264 | 314 | 375 | 453 | 527 | 592 | 678 | 0.0932 | 682 | 0.598 | 100.02 | 13.89 | 5 | 0.0927 | 216 | 0.0009 | 43.35 | 7.214 | 0.1661 | 199239.0 | 112000000 | 68300000000 | 44000000000000 | 0.3454 | 0.2664 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0000 | 0.0317 | 0.0172 | 0.1329 | 0.0499 | 0.2341 | 0.0946 | 0.2004 | 0.0851 | 0.1786 | 0.0997 | 0.2143 | 0.6535 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0060 | 0.0052 | 0.0268 | 0.0215 | 0.0357 | 0.0302 | 0.0402 | 0.0279 | 0.0462 | 0.0296 | 0.8444 | 0.8857 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0024 | 0.0000 | 0.0060 | 0.0107 | 0.0441 | 0.0661 | 0.0691 | 0.0946 | 0.0524 | 0.0643 | 0.0799 | 0.1143 | 0.7461 | 0.6482 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0399 | 0.0463 | 0.0399 | 0.0704 | 0.7998 | 21 | 27 | 31 | 34 | 38 | 44 | 54 | 94 | 219 | 0.1318 | 7.03 | 3.250 | 0.7401 | 28015.3 | 26600000 | 42300000000 | 80500000000000 | 0.5119 | 0.1569 | 0.0219 | 0.0200 | 0.0820 | 0.0234 | 0.1530 | 0.0443 | 0.1995 | 0.0747 | 0.2158 | 0.1354 | 0.1503 | 0.1458 | 0.0956 | 0.1519 | 0.0601 | 0.1632 | 0.0219 | 0.2413 | 0.0028 | 0.0096 | 0.0062 | 0.0104 | 0.0068 | 0.0183 | 0.0186 | 0.0246 | 0.0361 | 0.0445 | 0.0559 | 0.0512 | 0.0514 | 0.0608 | 0.0745 | 0.0908 | 0.7477 | 0.6898 | 0.0000 | 0.0000 | 0.0014 | 0.0032 | 0.0057 | 0.0064 | 0.0135 | 0.0216 | 0.0519 | 0.0632 | 0.0811 | 0.0800 | 0.0597 | 0.0752 | 0.0989 | 0.0992 | 0.6878 | 0.6512 | 0.0000 | 0.0000 | 0.0052 | 0.0181 | 0.0413 | 0.0664 | 0.0529 | 0.0896 | 0.7266 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 419 | 941 | | 1482 | 6727 | 623.1 | 187.74 | 39.98 | 47.19 | 345 | 427 | 507 | 585 | 646 | 704 | 748 | 798 | 856 | 0.0824 | 554 | 1.155 | 59.68 | 15.62 | 2 | 0.0857 | 127 | 0.0011 | 48.66 | 6.906 | 0.1667 | 423486.0 | 307000000 | 233000000000 | 182000000000000 | 0.3666 | 0.2504 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0009 | 0.0083 | 0.0077 | 0.0998 | 0.0404 | 0.1647 | 0.0482 | 0.1148 | 0.0490 | 0.1664 | 0.0782 | 0.4393 | 0.7756 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0023 | 0.0344 | 0.0313 | 0.0411 | 0.0313 | 0.0306 | 0.0305 | 0.0525 | 0.0477 | 0.8395 | 0.8569 | 0.0022 | 0.0172 | 0.0022 | 0.0000 | 0.0067 | 0.0517 | 0.0247 | 0.0345 | 0.0605 | 0.0862 | 0.0919 | 0.0862 | 0.0740 | 0.0948 | 0.0830 | 0.1207 | 0.6547 | 0.5086 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0375 | 0.0463 | 0.0438 | 0.0688 | 0.7938 | 9 | 12 | 15 | 18 | 23 | 29 | 37 | 55 | 98 | 0.0440 | 4.34 | 4.026 | 0.6372 | 3825.0 | 658362 | 157000000 | 45400000000 | 0.4438 | 0.2100 | 0.0158 | 0.0125 | 0.0565 | 0.0171 | 0.0949 | 0.0260 | 0.1616 | 0.0473 | 0.2011 | 0.0816 | 0.1638 | 0.1247 | 0.1333 | 0.1418 | 0.1209 | 0.1829 | 0.0520 | 0.3662 | 0.0041 | 0.0068 | 0.0127 | 0.0101 | 0.0151 | 0.0120 | 0.0262 | 0.0184 | 0.0454 | 0.0369 | 0.0654 | 0.0513 | 0.0634 | 0.0553 | 0.1079 | 0.0980 | 0.6599 | 0.7113 | 0.0019 | 0.0030 | 0.0038 | 0.0030 | 0.0122 | 0.0098 | 0.0275 | 0.0255 | 0.0487 | 0.0579 | 0.0890 | 0.0826 | 0.0602 | 0.0594 | 0.0922 | 0.0962 | 0.6643 | 0.6627 | 0.0053 | 0.0075 | 0.0150 | 0.0241 | 0.0470 | 0.0780 | 0.0625 | 0.0941 | 0.6665 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 826 | 768 | | 6744 | 16336 | 268.2 | 71.69 | 141.22 | 168.95 | 172 | 220 | 244 | 260 | 275 | 290 | 307 | 325 | 352 | 0.0586 | 958 | 0.774 | 134.30 | 33.11 | 3 | 0.0550 | 371 | 0.0010 | 38.65 | 7.160 | 0.1905 | 77081.5 | 23200000 | 7220000000 | 2320000000000 | 0.3771 | 0.2521 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0000 | 0.0202 | 0.0010 | 0.0641 | 0.0201 | 0.1133 | 0.0421 | 0.1271 | 0.0409 | 0.1690 | 0.0603 | 0.5009 | 0.8356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0022 | 0.0003 | 0.0193 | 0.0134 | 0.0351 | 0.0215 | 0.0430 | 0.0137 | 0.0639 | 0.0228 | 0.8363 | 0.9283 | 0.0020 | 0.0031 | 0.0094 | 0.0282 | 0.0201 | 0.0627 | 0.0602 | 0.1818 | 0.1145 | 0.1567 | 0.1667 | 0.2382 | 0.1245 | 0.1160 | 0.1506 | 0.1097 | 0.3521 | 0.1034 | 0.0005 | 0.0016 | 0.0054 | 0.0231 | 0.0549 | 0.0995 | 0.1012 | 0.1118 | 0.6018 | 11 | 13 | 17 | 33 | 74 | 117 | 174 | 256 | 384 | 0.1123 | 13.02 | 4.544 | 0.6051 | 48483.6 | 23400000 | 14000000000 | 9870000000000 | 0.3529 | 0.3072 | 0.0233 | 0.0006 | 0.0993 | 0.0098 | 0.1771 | 0.0540 | 0.1646 | 0.0816 | 0.1538 | 0.1403 | 0.1514 | 0.1788 | 0.0946 | 0.1438 | 0.0814 | 0.1444 | 0.0545 | 0.2467 | 0.0000 | 0.0000 | 0.0010 | 0.0014 | 0.0024 | 0.0015 | 0.0118 | 0.0068 | 0.0392 | 0.0287 | 0.0668 | 0.0517 | 0.0535 | 0.0373 | 0.0764 | 0.0617 | 0.7488 | 0.8108 | 0.0006 | 0.0011 | 0.0012 | 0.0025 | 0.0052 | 0.0039 | 0.0226 | 0.0215 | 0.0569 | 0.0753 | 0.0967 | 0.1142 | 0.0841 | 0.1007 | 0.1157 | 0.1304 | 0.6171 | 0.5504 | 0.0003 | 0.0014 | 0.0036 | 0.0128 | 0.0544 | 0.0778 | 0.0679 | 0.0958 | 0.6859 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 332 | 897 | | 4130 | 6420 | 525.0 | 190.33 | 45.50 | 77.20 | 256 | 314 | 388 | 474 | 542 | 599 | 659 | 716 | 767 | 0.1092 | 701 | 0.638 | 84.10 | 14.14 | 5 | 0.0482 | 199 | 0.0007 | 53.48 | 7.439 | 0.1929 | 311857.0 | 201000000 | 138000000000 | 98300000000000 | 0.3906 | 0.2301 | 0.0000 | 0.0015 | 0.0031 | 0.0011 | 0.0168 | 0.0011 | 0.0291 | 0.0083 | 0.1034 | 0.0496 | 0.1516 | 0.0931 | 0.1309 | 0.0644 | 0.1072 | 0.0966 | 0.4579 | 0.6842 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0018 | 0.0328 | 0.0255 | 0.0470 | 0.0436 | 0.0303 | 0.0252 | 0.0445 | 0.0370 | 0.8418 | 0.8670 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0021 | 0.0167 | 0.0104 | 0.0410 | 0.0494 | 0.0819 | 0.0626 | 0.1335 | 0.0494 | 0.1108 | 0.0745 | 0.1457 | 0.7516 | 0.4643 | 0.0000 | 0.0005 | 0.0005 | 0.0045 | 0.0352 | 0.0587 | 0.0352 | 0.0564 | 0.8090 | 8 | 10 | 13 | 15 | 17 | 22 | 31 | 60 | 119 | 0.0622 | 10.67 | 3.904 | 0.6364 | 8028.7 | 3400000 | 2280000000 | 1870000000000 | 0.5362 | 0.1440 | 0.0369 | 0.0169 | 0.0844 | 0.0226 | 0.1082 | 0.0463 | 0.1504 | 0.0993 | 0.1847 | 0.1366 | 0.1821 | 0.1061 | 0.1372 | 0.1163 | 0.0976 | 0.1558 | 0.0185 | 0.3002 | 0.0017 | 0.0057 | 0.0034 | 0.0076 | 0.0040 | 0.0086 | 0.0115 | 0.0195 | 0.0453 | 0.0437 | 0.0539 | 0.0518 | 0.0441 | 0.0456 | 0.0648 | 0.0699 | 0.7713 | 0.7476 | 0.0007 | 0.0025 | 0.0029 | 0.0016 | 0.0102 | 0.0074 | 0.0154 | 0.0164 | 0.0469 | 0.0402 | 0.0608 | 0.0731 | 0.0490 | 0.0484 | 0.0791 | 0.0649 | 0.7350 | 0.7455 | 0.0006 | 0.0051 | 0.0058 | 0.0135 | 0.0398 | 0.0630 | 0.0424 | 0.0694 | 0.7603 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 524 | 311 | | 7833 | 16316 | 159.4 | 129.05 | 84.65 | 174.06 | 65 | 76 | 86 | 97 | 114 | 131 | 150 | 185 | 382 | 0.0834 | 1360 | 1.188 | 60.96 | 23.71 | 5 | 0.0200 | 157 | 0.0057 | 7.18 | 5.903 | 0.4831 | 42052.4 | 16100000 | 7440000000 | 3750000000000 | 0.4134 | 0.2024 | 0.0022 | 0.0044 | 0.0039 | 0.0032 | 0.0061 | 0.0041 | 0.0335 | 0.0116 | 0.0754 | 0.0367 | 0.0972 | 0.0576 | 0.0972 | 0.0547 | 0.1056 | 0.0789 | 0.5788 | 0.7488 | 0.0012 | 0.0031 | 0.0021 | 0.0023 | 0.0027 | 0.0029 | 0.0140 | 0.0079 | 0.0273 | 0.0211 | 0.0334 | 0.0280 | 0.0404 | 0.0320 | 0.0507 | 0.0445 | 0.8282 | 0.8580 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0033 | 0.0000 | 0.0086 | 0.0022 | 0.0213 | 0.0230 | 0.0452 | 0.0445 | 0.0219 | 0.0208 | 0.0359 | 0.0408 | 0.8625 | 0.8687 | 0.0005 | 0.0039 | 0.0043 | 0.0096 | 0.0294 | 0.0487 | 0.0352 | 0.0545 | 0.8140 | 8 | 10 | 12 | 15 | 18 | 24 | 39 | 87 | 242 | 0.1992 | 8.64 | 2.988 | 0.7068 | 37461.6 | 26400000 | 22100000000 | 20600000000000 | 0.5330 | 0.1352 | 0.0090 | 0.0029 | 0.0336 | 0.0070 | 0.0493 | 0.0187 | 0.1087 | 0.0531 | 0.1659 | 0.0904 | 0.1839 | 0.1376 | 0.1390 | 0.1405 | 0.1312 | 0.1359 | 0.1794 | 0.4140 | 0.0005 | 0.0009 | 0.0029 | 0.0023 | 0.0029 | 0.0042 | 0.0098 | 0.0168 | 0.0383 | 0.0349 | 0.0554 | 0.0519 | 0.0449 | 0.0496 | 0.0660 | 0.0575 | 0.7794 | 0.7817 | 0.0021 | 0.0004 | 0.0017 | 0.0035 | 0.0045 | 0.0047 | 0.0141 | 0.0116 | 0.0497 | 0.0520 | 0.0783 | 0.0849 | 0.0583 | 0.0621 | 0.0852 | 0.0791 | 0.7060 | 0.7017 | 0.0009 | 0.0033 | 0.0045 | 0.0117 | 0.0415 | 0.0667 | 0.0505 | 0.0739 | 0.7471 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 652 | 166 | | 1359 | 6119 | 428.9 | 60.31 | 32.37 | 70.62 | 351 | 373 | 390 | 405 | 426 | 446 | 465 | 483 | 508 | 0.0709 | 434 | 0.794 | 97.08 | 19.70 | 1 | 0.1670 | 227 | 0.0023 | 22.07 | 6.272 | 0.2405 | 187585.0 | 83600000 | 38000000000 | 17500000000000 | 0.4204 | 0.2216 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0061 | 0.0000 | 0.0462 | 0.0221 | 0.0688 | 0.0324 | 0.0592 | 0.0191 | 0.0897 | 0.0316 | 0.7265 | 0.8948 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0016 | 0.0000 | 0.0293 | 0.0221 | 0.0443 | 0.0324 | 0.0332 | 0.0191 | 0.0546 | 0.0316 | 0.8347 | 0.8948 | 0.0259 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0776 | 0.0000 | 0.1638 | 0.0000 | 0.1983 | 0.0000 | 0.1207 | 0.0000 | 0.1379 | 0.0000 | 0.2759 | 0.0000 | 0.0000 | 0.0046 | 0.0077 | 0.0107 | 0.0475 | 0.0644 | 0.0706 | 0.0982 | 0.6963 | 6 | 8 | 9 | 10 | 11 | 13 | 15 | 23 | 79 | 0.3514 | 3.58 | 2.313 | 0.8106 | 6034.5 | 2460000 | 1350000000 | 863000000000 | 0.6003 | 0.1052 | 0.0807 | 0.0227 | 0.0807 | 0.0644 | 0.1211 | 0.0814 | 0.2870 | 0.1458 | 0.1435 | 0.1496 | 0.1480 | 0.1458 | 0.0762 | 0.1326 | 0.0583 | 0.1307 | 0.0045 | 0.1269 | 0.0088 | 0.0079 | 0.0044 | 0.0186 | 0.0071 | 0.0193 | 0.0274 | 0.0336 | 0.0398 | 0.0480 | 0.0548 | 0.0523 | 0.0610 | 0.0651 | 0.0839 | 0.0938 | 0.7129 | 0.6614 | 0.0000 | 0.0000 | 0.0044 | 0.0023 | 0.0055 | 0.0046 | 0.0143 | 0.0161 | 0.0539 | 0.0506 | 0.0462 | 0.0598 | 0.0616 | 0.0529 | 0.0935 | 0.0978 | 0.7206 | 0.7158 | 0.0020 | 0.0050 | 0.0090 | 0.0160 | 0.0548 | 0.0439 | 0.0499 | 0.1017 | 0.7178 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 149 | 240 | | 6671 | 12334 | 390.0 | 50.74 | 109.56 | 270.04 | 317 | 352 | 374 | 389 | 399 | 409 | 419 | 431 | 446 | 0.0712 | 878 | 0.700 | 125.40 | 29.61 | 3 | 0.0475 | 317 | 0.0019 | 22.81 | 6.624 | 0.2349 | 154695.0 | 62200000 | 25300000000 | 10400000000000 | 0.4580 | 0.1948 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0037 | 0.0003 | 0.0169 | 0.0112 | 0.0407 | 0.0210 | 0.0412 | 0.0134 | 0.0715 | 0.0187 | 0.8249 | 0.9354 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0003 | 0.0133 | 0.0112 | 0.0316 | 0.0210 | 0.0235 | 0.0134 | 0.0319 | 0.0187 | 0.8969 | 0.9354 | 0.1176 | 0.0000 | 0.1438 | 0.0000 | 0.1373 | 0.0000 | 0.1830 | 0.0000 | 0.1111 | 0.0000 | 0.1569 | 0.0000 | 0.0261 | 0.0000 | 0.0523 | 0.0000 | 0.0719 | 0.0000 | 0.0020 | 0.0033 | 0.0091 | 0.0202 | 0.0463 | 0.0663 | 0.0825 | 0.1189 | 0.6514 | 9 | 11 | 12 | 14 | 15 | 18 | 24 | 59 | 344 | 0.2142 | 6.81 | 2.736 | 0.6641 | 84919.1 | 101000000 | 144000000000 | 229000000000000 | 0.5929 | 0.1077 | 0.0204 | 0.0068 | 0.0980 | 0.0068 | 0.1592 | 0.0492 | 0.1878 | 0.0881 | 0.2082 | 0.1593 | 0.1755 | 0.1864 | 0.1020 | 0.1203 | 0.0367 | 0.1661 | 0.0122 | 0.2169 | 0.0005 | 0.0017 | 0.0019 | 0.0004 | 0.0014 | 0.0034 | 0.0052 | 0.0085 | 0.0331 | 0.0296 | 0.0553 | 0.0525 | 0.0355 | 0.0407 | 0.0766 | 0.0805 | 0.7905 | 0.7827 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0021 | 0.0017 | 0.0064 | 0.0079 | 0.0380 | 0.0350 | 0.0545 | 0.0599 | 0.0401 | 0.0418 | 0.0866 | 0.0870 | 0.7722 | 0.7662 | 0.0000 | 0.0000 | 0.0020 | 0.0076 | 0.0289 | 0.0613 | 0.0370 | 0.0770 | 0.7863 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 382 | 482 | | 6733 | 6438 | 43.2 | 12.21 | 112.41 | 165.59 | 28 | 32 | 35 | 39 | 42 | 46 | 50 | 54 | 60 | 0.1785 | 1149 | 1.039 | 54.34 | 16.16 | 3 | 0.0192 | 129 | 0.0360 | 0.84 | 3.592 | 0.6983 | 2014.6 | 100311 | 5270000 | 290000000 | 0.3887 | 0.2344 | 0.0060 | 0.0014 | 0.0139 | 0.0039 | 0.0220 | 0.0043 | 0.0460 | 0.0107 | 0.0794 | 0.0318 | 0.1389 | 0.0469 | 0.1480 | 0.0529 | 0.1880 | 0.0959 | 0.3578 | 0.7522 | 0.0027 | 0.0005 | 0.0041 | 0.0010 | 0.0078 | 0.0010 | 0.0188 | 0.0052 | 0.0347 | 0.0229 | 0.0580 | 0.0316 | 0.0586 | 0.0321 | 0.0858 | 0.0495 | 0.7295 | 0.8563 | 0.0070 | 0.0313 | 0.0186 | 0.0224 | 0.0256 | 0.0328 | 0.0413 | 0.0627 | 0.0721 | 0.0687 | 0.0809 | 0.1224 | 0.0878 | 0.1328 | 0.1268 | 0.1597 | 0.5398 | 0.3672 | 0.0033 | 0.0090 | 0.0189 | 0.0269 | 0.0452 | 0.0619 | 0.0736 | 0.0984 | 0.6628 | 7 | 8 | 10 | 12 | 19 | 48 | 124 | 221 | 345 | 0.0718 | 6.66 | 3.779 | 0.5031 | 40050.5 | 19600000 | 11300000000 | 7260000000000 | 0.4549 | 0.1859 | 0.0359 | 0.0046 | 0.1257 | 0.0170 | 0.2036 | 0.0880 | 0.1916 | 0.1173 | 0.1796 | 0.1867 | 0.1168 | 0.1929 | 0.0778 | 0.1312 | 0.0539 | 0.1281 | 0.0150 | 0.1343 | 0.0005 | 0.0008 | 0.0014 | 0.0021 | 0.0023 | 0.0008 | 0.0087 | 0.0068 | 0.0407 | 0.0343 | 0.0535 | 0.0525 | 0.0512 | 0.0423 | 0.0699 | 0.0728 | 0.7719 | 0.7875 | 0.0005 | 0.0000 | 0.0000 | 0.0012 | 0.0022 | 0.0041 | 0.0097 | 0.0146 | 0.0529 | 0.0578 | 0.0707 | 0.0776 | 0.0723 | 0.0712 | 0.0960 | 0.0968 | 0.6958 | 0.6768 | 0.0000 | 0.0010 | 0.0035 | 0.0144 | 0.0416 | 0.0575 | 0.0615 | 0.0878 | 0.7328 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 309 | 287 | | 6693 | 13038 | 535.8 | 126.02 | 220.15 | 377.39 | 361 | 403 | 454 | 495 | 535 | 584 | 628 | 661 | 696 | 0.0639 | 833 | 0.910 | 75.03 | 22.56 | 1 | 0.0288 | 193 | 0.0006 | 30.06 | 7.569 | 0.2086 | 303013.0 | 179000000 | 110000000000 | 69800000000000 | 0.3886 | 0.2484 | 0.0015 | 0.0000 | 0.0045 | 0.0003 | 0.0063 | 0.0009 | 0.0218 | 0.0046 | 0.0499 | 0.0146 | 0.0646 | 0.0195 | 0.0738 | 0.0255 | 0.0999 | 0.0304 | 0.6777 | 0.9041 | 0.0002 | 0.0000 | 0.0006 | 0.0002 | 0.0000 | 0.0006 | 0.0040 | 0.0031 | 0.0151 | 0.0121 | 0.0173 | 0.0144 | 0.0213 | 0.0153 | 0.0279 | 0.0185 | 0.9136 | 0.9358 | 0.0000 | 0.0057 | 0.0066 | 0.0230 | 0.0119 | 0.0575 | 0.0328 | 0.0862 | 0.0519 | 0.1552 | 0.0781 | 0.1092 | 0.0972 | 0.1322 | 0.1151 | 0.1379 | 0.6064 | 0.2931 | 0.0003 | 0.0012 | 0.0018 | 0.0075 | 0.0221 | 0.0392 | 0.0374 | 0.0502 | 0.8404 | 9 | 11 | 13 | 16 | 29 | 82 | 190 | 352 | 702 | 0.1372 | 64.08 | 4.831 | 0.5651 | 190878.0 | 238000000 | 347000000000 | 556000000000000 | 0.2850 | 0.3373 | 0.0407 | 0.0012 | 0.1423 | 0.0098 | 0.1842 | 0.0952 | 0.1160 | 0.1173 | 0.1651 | 0.1419 | 0.1471 | 0.1751 | 0.0969 | 0.1204 | 0.0682 | 0.1106 | 0.0395 | 0.2285 | 0.0000 | 0.0000 | 0.0010 | 0.0002 | 0.0030 | 0.0007 | 0.0114 | 0.0099 | 0.0445 | 0.0399 | 0.0736 | 0.0527 | 0.0521 | 0.0432 | 0.0692 | 0.0647 | 0.7453 | 0.7886 | 0.0012 | 0.0003 | 0.0000 | 0.0010 | 0.0028 | 0.0059 | 0.0177 | 0.0200 | 0.0570 | 0.0596 | 0.0906 | 0.0950 | 0.0548 | 0.0665 | 0.0878 | 0.0871 | 0.6880 | 0.6646 | 0.0006 | 0.0008 | 0.0019 | 0.0171 | 0.0521 | 0.0803 | 0.0576 | 0.0745 | 0.7151 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 772 | 323 | | 794 | 7091 | 484.4 | 65.35 | 36.00 | 48.85 | 404 | 424 | 442 | 460 | 481 | 495 | 518 | 543 | 578 | 0.0636 | 451 | 0.996 | 53.60 | 13.89 | 2 | 0.1612 | 128 | 0.0034 | 13.68 | 5.871 | 0.2779 | 238955.0 | 120000000 | 61300000000 | 31900000000000 | 0.3670 | 0.2688 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0132 | 0.0038 | 0.0471 | 0.0315 | 0.0838 | 0.0693 | 0.0632 | 0.0290 | 0.0897 | 0.0453 | 0.7015 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0038 | 0.0330 | 0.0315 | 0.0607 | 0.0693 | 0.0356 | 0.0290 | 0.0567 | 0.0453 | 0.8047 | 0.8212 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0385 | 0.0000 | 0.0513 | 0.0000 | 0.0897 | 0.0000 | 0.1538 | 0.0000 | 0.0769 | 0.0000 | 0.1795 | 0.0000 | 0.4103 | 0.0000 | 0.0000 | 0.0000 | 0.0105 | 0.0210 | 0.0525 | 0.0787 | 0.0709 | 0.0787 | 0.6877 | 8 | 10 | 12 | 15 | 19 | 24 | 32 | 46 | 83 | 0.0654 | 8.26 | 3.794 | 0.6602 | 3682.1 | 710852 | 183000000 | 55400000000 | 0.4200 | 0.2030 | 0.0272 | 0.0084 | 0.0680 | 0.0199 | 0.1088 | 0.0383 | 0.1519 | 0.0577 | 0.1927 | 0.1013 | 0.1621 | 0.1448 | 0.1361 | 0.1401 | 0.0964 | 0.1758 | 0.0567 | 0.3137 | 0.0038 | 0.0044 | 0.0071 | 0.0076 | 0.0134 | 0.0126 | 0.0217 | 0.0199 | 0.0459 | 0.0354 | 0.0584 | 0.0527 | 0.0764 | 0.0594 | 0.0889 | 0.0916 | 0.6845 | 0.7164 | 0.0013 | 0.0032 | 0.0066 | 0.0056 | 0.0119 | 0.0071 | 0.0291 | 0.0333 | 0.0984 | 0.0881 | 0.0905 | 0.1079 | 0.0707 | 0.1000 | 0.1288 | 0.1087 | 0.5627 | 0.5460 | 0.0011 | 0.0069 | 0.0058 | 0.0185 | 0.0627 | 0.0801 | 0.0764 | 0.1091 | 0.6394 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 517 | 209 | | 10942 | 35449 | 447.3 | 110.82 | 142.08 | 205.96 | 312 | 350 | 381 | 410 | 439 | 469 | 501 | 538 | 598 | 0.0363 | 1286 | 0.903 | 94.01 | 21.02 | 3 | 0.0206 | 225 | 0.0006 | 67.31 | 7.714 | 0.1503 | 212393.0 | 107000000 | 56200000000 | 31100000000000 | 0.4346 | 0.2214 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0003 | 0.0220 | 0.0020 | 0.0807 | 0.0222 | 0.1586 | 0.0494 | 0.1521 | 0.0568 | 0.1699 | 0.0831 | 0.4104 | 0.7861 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0069 | 0.0010 | 0.0331 | 0.0142 | 0.0664 | 0.0263 | 0.0584 | 0.0248 | 0.0766 | 0.0387 | 0.7570 | 0.8948 | 0.0022 | 0.0069 | 0.0081 | 0.0139 | 0.0103 | 0.0416 | 0.0550 | 0.1150 | 0.1279 | 0.1967 | 0.1699 | 0.1884 | 0.1225 | 0.1177 | 0.1516 | 0.1399 | 0.3524 | 0.1801 | 0.0008 | 0.0008 | 0.0065 | 0.0223 | 0.0687 | 0.1106 | 0.0929 | 0.1244 | 0.5730 | 7 | 10 | 12 | 15 | 24 | 71 | 163 | 276 | 443 | 0.1042 | 31.77 | 4.906 | 0.5483 | 62607.4 | 38100000 | 28100000000 | 23900000000000 | 0.4712 | 0.1726 | 0.0362 | 0.0022 | 0.1614 | 0.0112 | 0.2304 | 0.0744 | 0.1585 | 0.1487 | 0.1473 | 0.1922 | 0.1121 | 0.1786 | 0.0662 | 0.1198 | 0.0498 | 0.1135 | 0.0382 | 0.1594 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0067 | 0.0061 | 0.0345 | 0.0311 | 0.0658 | 0.0530 | 0.0462 | 0.0389 | 0.0718 | 0.0600 | 0.7738 | 0.8102 | 0.0000 | 0.0005 | 0.0006 | 0.0007 | 0.0010 | 0.0021 | 0.0102 | 0.0107 | 0.0492 | 0.0560 | 0.0855 | 0.0946 | 0.0637 | 0.0738 | 0.0966 | 0.1019 | 0.6933 | 0.6595 | 0.0002 | 0.0003 | 0.0018 | 0.0074 | 0.0431 | 0.0740 | 0.0560 | 0.0876 | 0.7297 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 921 | 862 | | 6477 | 15065 | 403.9 | 109.37 | 121.63 | 165.75 | 277 | 309 | 337 | 363 | 389 | 418 | 449 | 490 | 551 | 0.0525 | 791 | 0.968 | 109.17 | 33.06 | 1 | 0.0426 | 276 | 0.0006 | 77.54 | 7.589 | 0.1419 | 175073.0 | 81300000 | 40400000000 | 21300000000000 | 0.4463 | 0.2101 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0155 | 0.0004 | 0.0348 | 0.0028 | 0.1035 | 0.0244 | 0.1860 | 0.0559 | 0.1699 | 0.0627 | 0.1719 | 0.0842 | 0.3162 | 0.7696 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0023 | 0.0002 | 0.0093 | 0.0018 | 0.0399 | 0.0117 | 0.0837 | 0.0302 | 0.0747 | 0.0280 | 0.0983 | 0.0411 | 0.6910 | 0.8871 | 0.0029 | 0.0053 | 0.0174 | 0.0106 | 0.0101 | 0.0301 | 0.0702 | 0.0816 | 0.1259 | 0.1667 | 0.1802 | 0.1613 | 0.0948 | 0.1241 | 0.1324 | 0.1436 | 0.3661 | 0.2766 | 0.0003 | 0.0010 | 0.0055 | 0.0331 | 0.0776 | 0.1479 | 0.1117 | 0.1317 | 0.4912 | 7 | 9 | 13 | 25 | 47 | 84 | 137 | 215 | 339 | 0.0659 | 15.12 | 4.966 | 0.5541 | 42265.8 | 22000000 | 14400000000 | 10800000000000 | 0.3883 | 0.2650 | 0.0173 | 0.0015 | 0.0965 | 0.0090 | 0.2033 | 0.0324 | 0.1790 | 0.0799 | 0.1931 | 0.1735 | 0.1468 | 0.2123 | 0.0950 | 0.1508 | 0.0502 | 0.1388 | 0.0188 | 0.2017 | 0.0002 | 0.0002 | 0.0013 | 0.0011 | 0.0020 | 0.0012 | 0.0089 | 0.0089 | 0.0379 | 0.0318 | 0.0609 | 0.0533 | 0.0508 | 0.0440 | 0.0713 | 0.0640 | 0.7668 | 0.7956 | 0.0000 | 0.0003 | 0.0007 | 0.0005 | 0.0044 | 0.0032 | 0.0125 | 0.0119 | 0.0504 | 0.0631 | 0.0900 | 0.0998 | 0.0666 | 0.0700 | 0.0928 | 0.1054 | 0.6826 | 0.6458 | 0.0002 | 0.0002 | 0.0026 | 0.0098 | 0.0427 | 0.0786 | 0.0642 | 0.0823 | 0.7195 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 407 | 716 | | 7114 | 12770 | 534.1 | 94.65 | 61.96 | 146.06 | 380 | 451 | 508 | 534 | 555 | 577 | 594 | 611 | 633 | 0.0662 | 846 | 0.850 | 97.59 | 26.25 | 2 | 0.0417 | 297 | 0.0011 | 32.30 | 7.208 | 0.2276 | 294243.0 | 166000000 | 95600000000 | 55900000000000 | 0.4540 | 0.2027 | 0.0002 | 0.0001 | 0.0009 | 0.0006 | 0.0015 | 0.0003 | 0.0052 | 0.0017 | 0.0232 | 0.0121 | 0.0462 | 0.0176 | 0.0420 | 0.0150 | 0.0641 | 0.0232 | 0.8167 | 0.9294 | 0.0002 | 0.0001 | 0.0003 | 0.0006 | 0.0002 | 0.0003 | 0.0007 | 0.0017 | 0.0128 | 0.0121 | 0.0245 | 0.0176 | 0.0130 | 0.0150 | 0.0239 | 0.0232 | 0.9245 | 0.9294 | 0.0121 | 0.0000 | 0.0208 | 0.0000 | 0.0363 | 0.0000 | 0.0813 | 0.0000 | 0.1142 | 0.0000 | 0.1280 | 0.0000 | 0.1090 | 0.0000 | 0.1228 | 0.0000 | 0.3754 | 0.0000 | 0.0005 | 0.0014 | 0.0054 | 0.0119 | 0.0261 | 0.0428 | 0.0447 | 0.0612 | 0.8061 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 33 | 165 | 0.1905 | 3.26 | 2.362 | 0.6175 | 25171.9 | 16600000 | 13100000000 | 11600000000000 | 0.6507 | 0.0699 | 0.0193 | 0.0057 | 0.1322 | 0.0086 | 0.2204 | 0.0743 | 0.1736 | 0.1329 | 0.1267 | 0.2157 | 0.0909 | 0.1571 | 0.0716 | 0.0929 | 0.0661 | 0.1114 | 0.0992 | 0.2014 | 0.0000 | 0.0008 | 0.0009 | 0.0008 | 0.0031 | 0.0028 | 0.0098 | 0.0102 | 0.0459 | 0.0468 | 0.0570 | 0.0533 | 0.0459 | 0.0403 | 0.0731 | 0.0744 | 0.7643 | 0.7706 | 0.0011 | 0.0006 | 0.0021 | 0.0017 | 0.0069 | 0.0040 | 0.0133 | 0.0108 | 0.0436 | 0.0483 | 0.0760 | 0.0802 | 0.0452 | 0.0495 | 0.0803 | 0.0870 | 0.7315 | 0.7180 | 0.0005 | 0.0019 | 0.0048 | 0.0150 | 0.0446 | 0.0650 | 0.0509 | 0.0805 | 0.7368 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1130 | 267 | | 5490 | 23038 | 164.0 | 66.56 | 28.31 | 61.33 | 83 | 103 | 121 | 140 | 156 | 173 | 190 | 215 | 271 | 0.0512 | 1180 | 0.983 | 61.59 | 20.03 | 5 | 0.0288 | 158 | 0.0023 | 6.37 | 6.316 | 0.3881 | 31316.4 | 6760000 | 1600000000 | 408000000000 | 0.3733 | 0.2534 | 0.0000 | 0.0000 | 0.0019 | 0.0025 | 0.0077 | 0.0028 | 0.0178 | 0.0083 | 0.0548 | 0.0230 | 0.0836 | 0.0418 | 0.1000 | 0.0452 | 0.1629 | 0.0593 | 0.5714 | 0.8171 | 0.0000 | 0.0000 | 0.0011 | 0.0015 | 0.0023 | 0.0018 | 0.0056 | 0.0051 | 0.0158 | 0.0124 | 0.0237 | 0.0218 | 0.0259 | 0.0218 | 0.0440 | 0.0294 | 0.8816 | 0.9062 | 0.0027 | 0.0011 | 0.0075 | 0.0054 | 0.0137 | 0.0087 | 0.0239 | 0.0130 | 0.0321 | 0.0369 | 0.0498 | 0.0510 | 0.0546 | 0.0304 | 0.0539 | 0.0542 | 0.7618 | 0.7993 | 0.0000 | 0.0012 | 0.0056 | 0.0164 | 0.0308 | 0.0504 | 0.0496 | 0.0712 | 0.7747 | 7 | 9 | 10 | 12 | 13 | 15 | 18 | 25 | 46 | 0.1947 | 4.25 | 2.622 | 0.7761 | 4562.8 | 1730000 | 803000000 | 408000000000 | 0.5689 | 0.1210 | 0.0523 | 0.0587 | 0.0562 | 0.0581 | 0.0812 | 0.0637 | 0.1251 | 0.0665 | 0.1413 | 0.0729 | 0.1613 | 0.0863 | 0.1935 | 0.0999 | 0.1268 | 0.1500 | 0.0623 | 0.3441 | 0.0140 | 0.0361 | 0.0138 | 0.0353 | 0.0177 | 0.0353 | 0.0272 | 0.0346 | 0.0400 | 0.0414 | 0.0560 | 0.0533 | 0.0641 | 0.0585 | 0.0971 | 0.0880 | 0.6701 | 0.6175 | 0.0057 | 0.0047 | 0.0093 | 0.0061 | 0.0131 | 0.0140 | 0.0191 | 0.0201 | 0.0508 | 0.0635 | 0.0669 | 0.0793 | 0.0770 | 0.0840 | 0.1123 | 0.1231 | 0.6459 | 0.6053 | 0.0104 | 0.0106 | 0.0164 | 0.0205 | 0.0425 | 0.0614 | 0.0594 | 0.1068 | 0.6718 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 508 | 386 | | 1856 | 6121 | 930.2 | 328.29 | 7.48 | 2.44 | 554 | 653 | 741 | 809 | 938 | 1045 | 1136 | 1227 | 1377 | 0.0853 | 522 | 1.026 | 43.86 | 14.14 | 1 | 0.0641 | 119 | 0.0008 | 115.28 | 7.271 | 0.1207 | 972996.0 | 1100000000 | 1310000000000 | 1.62E+15 | 0.4447 | 0.1728 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0173 | 0.0007 | 0.0317 | 0.0064 | 0.1400 | 0.0443 | 0.2107 | 0.1180 | 0.1486 | 0.0730 | 0.1962 | 0.1001 | 0.2554 | 0.6574 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0006 | 0.0093 | 0.0030 | 0.0388 | 0.0270 | 0.0705 | 0.0642 | 0.0496 | 0.0354 | 0.0659 | 0.0564 | 0.7651 | 0.8134 | 0.0034 | 0.0000 | 0.0000 | 0.0074 | 0.0000 | 0.0037 | 0.0201 | 0.0260 | 0.0586 | 0.1078 | 0.1273 | 0.1933 | 0.0771 | 0.0818 | 0.1039 | 0.0855 | 0.6097 | 0.4944 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0427 | 0.0907 | 0.0491 | 0.0768 | 0.7353 | 5 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0178 | 7.81 | 4.411 | 0.3613 | 61.9 | 562.793 | 5603.58 | 60707.4 | 0.4721 | 0.1687 | 0.0133 | 0.0031 | 0.0511 | 0.0061 | 0.1011 | 0.0157 | 0.1867 | 0.0367 | 0.2357 | 0.0887 | 0.1933 | 0.1507 | 0.1532 | 0.2219 | 0.0544 | 0.2907 | 0.0113 | 0.1863 | 0.0006 | 0.0000 | 0.0046 | 0.0003 | 0.0191 | 0.0016 | 0.0469 | 0.0087 | 0.0879 | 0.0304 | 0.1387 | 0.0535 | 0.1808 | 0.0957 | 0.2333 | 0.2328 | 0.2882 | 0.5769 | 0.0957 | 0.1536 | 0.1428 | 0.1826 | 0.1400 | 0.1273 | 0.1328 | 0.0834 | 0.1079 | 0.0869 | 0.1063 | 0.0860 | 0.0847 | 0.0808 | 0.0841 | 0.0939 | 0.1057 | 0.1054 | 0.0056 | 0.0360 | 0.0685 | 0.1045 | 0.1391 | 0.1650 | 0.1550 | 0.1468 | 0.1796 |