High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MCF7
0
DRAQ5 1 TMRE 2 2 2 1 307 284 image if available 4454 15705 541.8 126.10 114.66 191.51 395 434 463 491 521 551 591 651 728 0.0554 870 1.060 102.88 27.59 2 0.0534 238 0.0008 82.33 7.369 0.1665 309466.0
186000000
118000000000
78000000000000
0.4066 0.2345 0.0007 0.0000 0.0030 0.0000 0.0097 0.0005 0.0157 0.0027 0.0737 0.0261 0.1377 0.0438 0.1448 0.0443 0.1534 0.0597 0.4611 0.8229 0.0003 0.0000 0.0000 0.0000 0.0011 0.0000 0.0056 0.0002 0.0407 0.0161 0.0709 0.0258 0.0709 0.0192 0.0895 0.0269 0.7210 0.9117 0.0022 0.0032 0.0000 0.0160 0.0078 0.0415 0.0526 0.0927 0.0973 0.1629 0.1353 0.1502 0.0839 0.1086 0.1074 0.1438 0.5134 0.2812 0.0000 0.0031 0.0062 0.0333 0.0868 0.1149 0.1004 0.1108 0.5445 5 7 8 10 11 17 98 220 400 0.1818 28.75 4.115 0.6043 49820.4
29100000
19900000000
15300000000000
0.3528 0.2965 0.0222 0.0027 0.0974 0.0054 0.2530 0.0467 0.2085 0.0916 0.1880 0.2163 0.1333 0.2720 0.0496 0.1517 0.0222 0.1086 0.0256 0.1050 0.0000 0.0000 0.0002 0.0002 0.0010 0.0002 0.0025 0.0028 0.0223 0.0206 0.0377 0.0307 0.0289 0.0256 0.0466 0.0365 0.8607 0.8834 0.0005 0.0003 0.0002 0.0005 0.0002 0.0005 0.0059 0.0071 0.0334 0.0374 0.0541 0.0695 0.0498 0.0450 0.0636 0.0730 0.7923 0.7666 0.0002 0.0000 0.0004 0.0042 0.0271 0.0491 0.0391 0.0560 0.8237
MCF 10A A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 1153 647 image if available 7001 25505 556.6 122.04 346.05 471.05 401 439 476 515 554 594 633 670 719 0.0502 1281 1.091 94.40 31.32 2 0.0330 231 0.0008 49.47 7.389 0.1879 324688.0
198000000
125000000000
81200000000000
0.4396 0.2100 0.0007 0.0000 0.0015 0.0000 0.0054 0.0002 0.0176 0.0008 0.0856 0.0167 0.1397 0.0345 0.1231 0.0336 0.1667 0.0500 0.4597 0.8643 0.0004 0.0000 0.0007 0.0000 0.0011 0.0000 0.0057 0.0003 0.0329 0.0127 0.0559 0.0246 0.0475 0.0180 0.0714 0.0252 0.7845 0.9193 0.0042 0.0190 0.0042 0.0521 0.0140 0.0474 0.0524 0.1232 0.1054 0.1943 0.1795 0.1848 0.1194 0.1327 0.1522 0.1137 0.3687 0.1327 0.0000 0.0026 0.0017 0.0185 0.0503 0.0888 0.0772 0.0943 0.6665 16 30 58 98 145 207 334 573 1040 0.0125 72.60 6.612 0.3697 341631.0
484000000
806000000000
1.47E+15
0.3657 0.3010 0.0271 0.0034 0.1024 0.0083 0.1982 0.0464 0.1992 0.1091 0.1937 0.1605 0.1274 0.2005 0.0763 0.1440 0.0457 0.1451 0.0301 0.1828 0.0006 0.0011 0.0022 0.0019 0.0049 0.0048 0.0175 0.0174 0.0458 0.0451 0.0736 0.0727 0.0584 0.0567 0.0751 0.0729 0.7219 0.7275 0.0005 0.0012 0.0032 0.0039 0.0065 0.0072 0.0159 0.0166 0.0490 0.0479 0.0772 0.0773 0.0599 0.0636 0.0830 0.0742 0.7047 0.7080 0.0005 0.0031 0.0048 0.0174 0.0468 0.0729 0.0592 0.0760 0.7193
MCF7 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 234 799 image if available 13982 47347 267.6 72.72 111.48 151.15 180 206 227 244 261 277 298 324 366 0.0290 1375 0.637 134.38 29.41 4 0.0255 356 0.0013 25.91 6.963 0.2170 76872.3
23600000
7750000000
2700000000000
0.4326 0.2214 0.0001 0.0000 0.0013 0.0001 0.0055 0.0004 0.0221 0.0029 0.0806 0.0231 0.1501 0.0550 0.1533 0.0526 0.1827 0.0775 0.4043 0.7885 0.0000 0.0000 0.0003 0.0000 0.0018 0.0002 0.0076 0.0010 0.0363 0.0137 0.0660 0.0277 0.0623 0.0230 0.0865 0.0394 0.7392 0.8952 0.0052 0.0034 0.0097 0.0101 0.0207 0.0151 0.0446 0.0772 0.1034 0.1394 0.1383 0.2065 0.0906 0.0999 0.1317 0.1360 0.4557 0.3123 0.0005 0.0028 0.0097 0.0328 0.0738 0.1215 0.0977 0.1158 0.5454 7 9 11 16 39 79 133 204 314 0.0819 10.81 4.504 0.5328 35272.3
16700000
10300000000
7940000000000
0.3283 0.3071 0.0637 0.0018 0.1924 0.0219 0.2593 0.1299 0.1590 0.1336 0.1409 0.1843 0.0919 0.1786 0.0492 0.1220 0.0306 0.1122 0.0130 0.1156 0.0001 0.0000 0.0004 0.0004 0.0007 0.0005 0.0071 0.0063 0.0513 0.0394 0.0875 0.0698 0.0707 0.0553 0.1096 0.0865 0.6726 0.7417 0.0003 0.0002 0.0010 0.0011 0.0030 0.0057 0.0155 0.0207 0.0717 0.0816 0.1258 0.1367 0.0873 0.0954 0.1313 0.1337 0.5642 0.5249 0.0001 0.0005 0.0021 0.0105 0.0627 0.1064 0.0809 0.1220 0.6149
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 826 768 image if available 6744 16336 268.2 71.69 141.22 168.95 172 220 244 260 275 290 307 325 352 0.0586 958 0.774 134.30 33.11 3 0.0550 371 0.0010 38.65 7.160 0.1905 77081.5
23200000
7220000000
2320000000000
0.3771 0.2521 0.0002 0.0000 0.0005 0.0000 0.0047 0.0000 0.0202 0.0010 0.0641 0.0201 0.1133 0.0421 0.1271 0.0409 0.1690 0.0603 0.5009 0.8356 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0022 0.0003 0.0193 0.0134 0.0351 0.0215 0.0430 0.0137 0.0639 0.0228 0.8363 0.9283 0.0020 0.0031 0.0094 0.0282 0.0201 0.0627 0.0602 0.1818 0.1145 0.1567 0.1667 0.2382 0.1245 0.1160 0.1506 0.1097 0.3521 0.1034 0.0005 0.0016 0.0054 0.0231 0.0549 0.0995 0.1012 0.1118 0.6018 11 13 17 33 74 117 174 256 384 0.1123 13.02 4.544 0.6051 48483.6
23400000
14000000000
9870000000000
0.3529 0.3072 0.0233 0.0006 0.0993 0.0098 0.1771 0.0540 0.1646 0.0816 0.1538 0.1403 0.1514 0.1788 0.0946 0.1438 0.0814 0.1444 0.0545 0.2467 0.0000 0.0000 0.0010 0.0014 0.0024 0.0015 0.0118 0.0068 0.0392 0.0287 0.0668 0.0517 0.0535 0.0373 0.0764 0.0617 0.7488 0.8108 0.0006 0.0011 0.0012 0.0025 0.0052 0.0039 0.0226 0.0215 0.0569 0.0753 0.0967 0.1142 0.0841 0.1007 0.1157 0.1304 0.6171 0.5504 0.0003 0.0014 0.0036 0.0128 0.0544 0.0778 0.0679 0.0958 0.6859
MCF7 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 162 234 image if available 7241 33553 311.8 96.47 118.63 162.69 187 201 237 287 318 345 372 400 436 0.0350 1175 0.651 97.19 15.30 2 0.0305 221 0.0011 37.81 7.274 0.2128 106500.0
39100000
15200000000
6200000000000
0.4774 0.1776 0.0004 0.0012 0.0025 0.0024 0.0078 0.0057 0.0252 0.0134 0.0900 0.0431 0.1460 0.0745 0.1488 0.0709 0.1729 0.1150 0.4064 0.6737 0.0000 0.0011 0.0000 0.0020 0.0012 0.0045 0.0020 0.0085 0.0163 0.0263 0.0285 0.0387 0.0281 0.0343 0.0386 0.0461 0.8853 0.8385 0.0024 0.0155 0.0043 0.0127 0.0119 0.0325 0.0396 0.0876 0.0835 0.1441 0.1098 0.1935 0.1150 0.1483 0.1394 0.1384 0.4940 0.2274 0.0000 0.0011 0.0029 0.0135 0.0296 0.0630 0.0643 0.0849 0.7407 9 11 14 19 34 73 138 222 342 0.1019 11.63 4.467 0.5909 40541.7
20200000
12600000000
9300000000000
0.3536 0.3217 0.0195 0.0035 0.1006 0.0081 0.1840 0.0477 0.1733 0.1043 0.1800 0.1722 0.1418 0.1779 0.1082 0.1344 0.0594 0.1368 0.0332 0.2151 0.0001 0.0006 0.0006 0.0005 0.0020 0.0011 0.0085 0.0076 0.0341 0.0295 0.0563 0.0485 0.0428 0.0362 0.0619 0.0541 0.7937 0.8219 0.0001 0.0002 0.0013 0.0015 0.0028 0.0035 0.0110 0.0135 0.0448 0.0478 0.0745 0.0869 0.0567 0.0645 0.0842 0.0980 0.7246 0.6843 0.0002 0.0009 0.0028 0.0099 0.0385 0.0629 0.0519 0.0705 0.7623
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 937 792 image if available 9123 21746 335.0 60.34 75.58 106.02 251 283 304 322 338 352 368 385 407 0.0469 1020 1.203 88.96 31.32 2 0.0240 219 0.0031 5.79 6.087 0.3990 115860.0
41200000
15100000000
5640000000000
0.3775 0.2592 0.0006 0.0000 0.0019 0.0001 0.0030 0.0007 0.0099 0.0012 0.0231 0.0099 0.0367 0.0248 0.0410 0.0160 0.0611 0.0234 0.8226 0.9239 0.0001 0.0000 0.0004 0.0000 0.0010 0.0003 0.0037 0.0008 0.0116 0.0086 0.0156 0.0195 0.0156 0.0089 0.0230 0.0132 0.9290 0.9487 0.0127 0.0397 0.0136 0.0397 0.0363 0.1429 0.0417 0.1190 0.0644 0.1587 0.0816 0.1905 0.0743 0.0635 0.0988 0.0952 0.5766 0.1508 0.0021 0.0040 0.0109 0.0129 0.0253 0.0322 0.0430 0.0670 0.8026 6 7 9 13 26 46 79 134 219 0.0597 7.19 4.039 0.5263 16952.4
5760000
2510000000
1300000000000
0.3182 0.3239 0.0564 0.0038 0.1472 0.0263 0.2620 0.0928 0.1675 0.1276 0.1368 0.1702 0.0969 0.1688 0.0595 0.1401 0.0485 0.1159 0.0252 0.1545 0.0001 0.0005 0.0012 0.0006 0.0032 0.0031 0.0151 0.0112 0.0474 0.0451 0.0827 0.0582 0.0582 0.0542 0.0838 0.0756 0.7083 0.7517 0.0012 0.0002 0.0012 0.0019 0.0027 0.0043 0.0211 0.0249 0.0642 0.0784 0.1127 0.1071 0.0701 0.0779 0.0991 0.1155 0.6278 0.5898 0.0006 0.0010 0.0024 0.0164 0.0621 0.0942 0.0691 0.0956 0.6587
Hs 578T
0
DRAQ5 1 TMRE 2 2 2 1 1125 641 image if available 11752 25342 232.5 61.19 170.59 255.96 162 186 201 215 228 242 257 278 310 0.0510 1293 1.092 30.46 9.43 3 0.0062 73 0.0008 52.10 7.510 0.1713 57786.2
15300000
4280000000
1270000000000
0.4266 0.2087 0.0003 0.0000 0.0011 0.0002 0.0038 0.0004 0.0137 0.0016 0.0570 0.0194 0.1221 0.0376 0.1242 0.0374 0.1725 0.0532 0.5053 0.8503 0.0002 0.0000 0.0004 0.0001 0.0015 0.0000 0.0056 0.0005 0.0238 0.0113 0.0480 0.0188 0.0513 0.0158 0.0752 0.0235 0.7940 0.9300 0.0039 0.0023 0.0117 0.0081 0.0174 0.0151 0.0516 0.0755 0.0951 0.1231 0.1428 0.1649 0.0872 0.1115 0.1228 0.1161 0.4674 0.3833 0.0018 0.0029 0.0093 0.0250 0.0622 0.0988 0.0949 0.1131 0.5921 9 12 17 32 58 95 152 272 534 0.0689 34.29 5.267 0.5297 94612.1
77200000
75700000000
83200000000000
0.3585 0.3278 0.0395 0.0012 0.1512 0.0108 0.2256 0.0794 0.1461 0.1072 0.1502 0.1684 0.1169 0.1823 0.0707 0.1281 0.0608 0.1168 0.0390 0.2056 0.0006 0.0003 0.0021 0.0014 0.0038 0.0026 0.0153 0.0136 0.0581 0.0480 0.0869 0.0812 0.0666 0.0586 0.0861 0.0828 0.6805 0.7116 0.0002 0.0007 0.0019 0.0034 0.0056 0.0081 0.0251 0.0236 0.0640 0.0649 0.0941 0.0908 0.0674 0.0685 0.0855 0.0777 0.6563 0.6622 0.0007 0.0013 0.0062 0.0194 0.0623 0.0938 0.0645 0.0859 0.6660
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 350 768 image if available 2148 7377 649.8 190.42 59.61 108.11 361 467 544 624 689 729 767 811 863 0.0729 538 0.439 61.06 9.22 3 0.0791 170 0.0009 72.75 7.161 0.1651 458473.0
344000000
270000000000
221000000000000
0.4160 0.2058 0.0000 0.0000 0.0000 0.0000 0.0050 0.0006 0.0291 0.0023 0.0824 0.0283 0.1568 0.0702 0.1075 0.0385 0.1397 0.0645 0.4794 0.7957 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0045 0.0016 0.0293 0.0240 0.0560 0.0464 0.0350 0.0235 0.0592 0.0427 0.8160 0.8617 0.0000 0.0094 0.0000 0.0283 0.0035 0.0189 0.0260 0.0566 0.0781 0.1415 0.1163 0.2264 0.0885 0.0472 0.1250 0.1038 0.5625 0.3679 0.0000 0.0000 0.0000 0.0091 0.0432 0.0639 0.0490 0.0763 0.7585 7 9 11 13 16 21 32 64 203 0.0746 10.49 3.983 0.6307 15239.4
6560000
3660000000
2420000000000
0.2920 0.3302 0.0000 0.0050 0.0655 0.0113 0.2143 0.0239 0.2292 0.0642 0.2054 0.1597 0.1429 0.2013 0.0774 0.1660 0.0506 0.1698 0.0149 0.1987 0.0000 0.0019 0.0017 0.0043 0.0040 0.0038 0.0115 0.0125 0.0340 0.0355 0.0530 0.0485 0.0363 0.0384 0.0594 0.0677 0.8000 0.7872 0.0000 0.0000 0.0000 0.0000 0.0043 0.0031 0.0129 0.0109 0.0372 0.0427 0.0558 0.0637 0.0393 0.0365 0.0629 0.0637 0.7877 0.7793 0.0000 0.0000 0.0007 0.0170 0.0352 0.0483 0.0463 0.0614 0.7911
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 800 501 image if available 13792 38751 266.6 61.19 169.99 277.73 192 219 237 253 267 281 297 317 345 0.0391 1515 0.913 98.60 27.17 6 0.0188 259 0.0012 28.43 7.043 0.2221 74836.6
21900000
6660000000
2090000000000
0.4163 0.2227 0.0000 0.0000 0.0013 0.0000 0.0034 0.0004 0.0145 0.0030 0.0508 0.0123 0.1000 0.0294 0.1083 0.0291 0.1428 0.0414 0.5789 0.8845 0.0000 0.0000 0.0006 0.0000 0.0009 0.0002 0.0051 0.0012 0.0181 0.0073 0.0381 0.0171 0.0415 0.0105 0.0570 0.0160 0.8387 0.9478 0.0032 0.0074 0.0083 0.0315 0.0221 0.0612 0.0437 0.1169 0.1095 0.1818 0.1536 0.1892 0.1312 0.1373 0.1276 0.1150 0.4009 0.1596 0.0001 0.0023 0.0069 0.0225 0.0520 0.0995 0.0920 0.1141 0.6107 11 14 16 21 32 62 139 285 553 0.1524 25.56 4.437 0.6078 106029.0
97600000
110000000000
141000000000000
0.3354 0.3305 0.0662 0.0027 0.2254 0.0240 0.2667 0.1419 0.1607 0.1818 0.1295 0.1818 0.0830 0.1829 0.0379 0.1071 0.0230 0.0916 0.0077 0.0861 0.0003 0.0003 0.0010 0.0006 0.0035 0.0021 0.0193 0.0153 0.0582 0.0549 0.0728 0.0726 0.0478 0.0442 0.0766 0.0719 0.7205 0.7381 0.0006 0.0007 0.0019 0.0018 0.0059 0.0059 0.0221 0.0258 0.0548 0.0602 0.0841 0.0861 0.0579 0.0644 0.0867 0.0924 0.6859 0.6628 0.0003 0.0015 0.0047 0.0221 0.0559 0.0766 0.0542 0.0790 0.7058
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 1168 309 image if available 5738 14541 555.0 97.99 135.57 201.88 430 475 509 532 549 569 595 630 674 0.0558 812 1.022 61.39 19.31 1 0.0284 163 0.0013 20.75 6.963 0.2451 317645.0
187000000
114000000000
71800000000000
0.4110 0.2319 0.0002 0.0000 0.0005 0.0002 0.0016 0.0000 0.0094 0.0011 0.0237 0.0134 0.0434 0.0246 0.0556 0.0175 0.0657 0.0266 0.8000 0.9168 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0050 0.0002 0.0111 0.0115 0.0231 0.0207 0.0271 0.0101 0.0293 0.0171 0.9045 0.9404 0.0060 0.0000 0.0119 0.0000 0.0179 0.0000 0.0448 0.0000 0.0746 0.0000 0.0896 0.0000 0.0940 0.0000 0.1284 0.0000 0.5328 0.0000 0.0037 0.0078 0.0108 0.0257 0.0310 0.0518 0.0567 0.0712 0.7411 6 9 11 15 31 63 129 257 447 0.0557 17.52 4.450 0.4770 59131.7
35000000
24100000000
18500000000000
0.2802 0.3316 0.0685 0.0029 0.2066 0.0315 0.2433 0.1562 0.1601 0.1358 0.1039 0.1713 0.0844 0.1871 0.0648 0.1125 0.0391 0.0857 0.0293 0.1171 0.0000 0.0000 0.0002 0.0008 0.0017 0.0011 0.0106 0.0101 0.0494 0.0398 0.0811 0.0787 0.0552 0.0482 0.0684 0.0622 0.7334 0.7591 0.0000 0.0008 0.0005 0.0014 0.0036 0.0028 0.0137 0.0194 0.0588 0.0540 0.0975 0.1111 0.0629 0.0684 0.0890 0.0925 0.6741 0.6495 0.0002 0.0007 0.0019 0.0127 0.0514 0.0927 0.0561 0.0791 0.7052
Hs 578T
0
DRAQ5 1 TMRE 2 2 2 1 334 363 image if available 15302 41714 244.9 60.87 131.95 179.42 171 196 213 227 242 257 273 292 320 0.0338 1411 0.710 67.01 10.63 1 0.0092 141 0.0009 32.33 7.369 0.2155 63663.8
17500000
5040000000
1520000000000
0.3811 0.2520 0.0003 0.0001 0.0018 0.0001 0.0054 0.0012 0.0129 0.0025 0.0443 0.0131 0.0775 0.0277 0.0883 0.0259 0.1303 0.0318 0.6391 0.8975 0.0001 0.0000 0.0009 0.0000 0.0019 0.0005 0.0043 0.0006 0.0157 0.0082 0.0271 0.0149 0.0311 0.0107 0.0502 0.0147 0.8688 0.9504 0.0040 0.0021 0.0074 0.0094 0.0148 0.0178 0.0415 0.0545 0.0820 0.1027 0.1180 0.1394 0.0981 0.1038 0.1164 0.1153 0.5177 0.4549 0.0010 0.0043 0.0084 0.0193 0.0357 0.0673 0.0704 0.0887 0.7048 13 17 21 29 47 80 136 229 381 0.0427 30.07 5.192 0.5095 49598.6
28100000
20000000000
16800000000000
0.3211 0.3337 0.0612 0.0021 0.1948 0.0183 0.2759 0.1123 0.1692 0.1501 0.1266 0.2025 0.0897 0.1912 0.0381 0.1170 0.0295 0.0975 0.0151 0.1089 0.0001 0.0001 0.0003 0.0005 0.0017 0.0013 0.0140 0.0104 0.0568 0.0497 0.0959 0.0827 0.0647 0.0548 0.0965 0.0855 0.6699 0.7149 0.0002 0.0004 0.0005 0.0012 0.0029 0.0045 0.0170 0.0211 0.0778 0.0843 0.1185 0.1332 0.0800 0.0874 0.1208 0.1226 0.5822 0.5453 0.0002 0.0013 0.0024 0.0139 0.0650 0.1091 0.0726 0.1074 0.6281
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 309 287 image if available 6693 13038 535.8 126.02 220.15 377.39 361 403 454 495 535 584 628 661 696 0.0639 833 0.910 75.03 22.56 1 0.0288 193 0.0006 30.06 7.569 0.2086 303013.0
179000000
110000000000
69800000000000
0.3886 0.2484 0.0015 0.0000 0.0045 0.0003 0.0063 0.0009 0.0218 0.0046 0.0499 0.0146 0.0646 0.0195 0.0738 0.0255 0.0999 0.0304 0.6777 0.9041 0.0002 0.0000 0.0006 0.0002 0.0000 0.0006 0.0040 0.0031 0.0151 0.0121 0.0173 0.0144 0.0213 0.0153 0.0279 0.0185 0.9136 0.9358 0.0000 0.0057 0.0066 0.0230 0.0119 0.0575 0.0328 0.0862 0.0519 0.1552 0.0781 0.1092 0.0972 0.1322 0.1151 0.1379 0.6064 0.2931 0.0003 0.0012 0.0018 0.0075 0.0221 0.0392 0.0374 0.0502 0.8404 9 11 13 16 29 82 190 352 702 0.1372 64.08 4.831 0.5651 190878.0
238000000
347000000000
556000000000000
0.2850 0.3373 0.0407 0.0012 0.1423 0.0098 0.1842 0.0952 0.1160 0.1173 0.1651 0.1419 0.1471 0.1751 0.0969 0.1204 0.0682 0.1106 0.0395 0.2285 0.0000 0.0000 0.0010 0.0002 0.0030 0.0007 0.0114 0.0099 0.0445 0.0399 0.0736 0.0527 0.0521 0.0432 0.0692 0.0647 0.7453 0.7886 0.0012 0.0003 0.0000 0.0010 0.0028 0.0059 0.0177 0.0200 0.0570 0.0596 0.0906 0.0950 0.0548 0.0665 0.0878 0.0871 0.6880 0.6646 0.0006 0.0008 0.0019 0.0171 0.0521 0.0803 0.0576 0.0745 0.7151
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 609 251 image if available 8474 32235 492.3 132.68 164.80 304.29 304 403 447 478 505 531 562 596 642 0.0423 1362 0.553 103.04 22.02 6 0.0340 288 0.0004 114.84 8.011 0.1304 259967.0
144000000
83000000000
49400000000000
0.3722 0.2591 0.0000 0.0000 0.0008 0.0000 0.0037 0.0003 0.0143 0.0023 0.0499 0.0166 0.1100 0.0376 0.1112 0.0351 0.1452 0.0452 0.5648 0.8630 0.0000 0.0000 0.0001 0.0000 0.0003 0.0001 0.0025 0.0009 0.0146 0.0117 0.0325 0.0201 0.0307 0.0127 0.0470 0.0181 0.8723 0.9363 0.0022 0.0048 0.0077 0.0143 0.0132 0.0286 0.0548 0.0835 0.1064 0.2124 0.1656 0.1742 0.1162 0.1074 0.1436 0.1480 0.3904 0.2267 0.0004 0.0024 0.0034 0.0209 0.0482 0.0869 0.0897 0.1054 0.6428 11 14 16 19 25 41 97 243 543 0.1744 25.68 4.127 0.6433 119746.0
132000000
179000000000
274000000000000
0.3012 0.3397 0.0899 0.0040 0.2395 0.0218 0.2653 0.1374 0.1444 0.1732 0.1091 0.1910 0.0818 0.1739 0.0413 0.1102 0.0177 0.0848 0.0111 0.1039 0.0005 0.0004 0.0016 0.0005 0.0018 0.0022 0.0158 0.0127 0.0501 0.0477 0.0704 0.0633 0.0461 0.0432 0.0696 0.0655 0.7443 0.7646 0.0003 0.0003 0.0003 0.0026 0.0043 0.0048 0.0182 0.0201 0.0595 0.0574 0.0778 0.0868 0.0553 0.0575 0.0768 0.0805 0.7076 0.6901 0.0004 0.0001 0.0031 0.0149 0.0534 0.0785 0.0435 0.0762 0.7299
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 296 572 image if available 8086 26684 302.2 79.97 205.86 280.95 205 239 262 283 304 326 349 373 401 0.0475 1267 0.665 59.68 11.31 3 0.0177 143 0.0008 40.70 7.343 0.1978 97719.6
33200000
11800000000
4310000000000
0.3795 0.2472 0.0011 0.0000 0.0016 0.0000 0.0074 0.0003 0.0207 0.0023 0.0767 0.0172 0.1294 0.0437 0.1280 0.0397 0.1701 0.0578 0.4650 0.8391 0.0002 0.0000 0.0006 0.0000 0.0016 0.0000 0.0058 0.0012 0.0212 0.0116 0.0426 0.0234 0.0420 0.0137 0.0672 0.0206 0.8188 0.9295 0.0020 0.0068 0.0051 0.0228 0.0164 0.0387 0.0475 0.1048 0.0915 0.2096 0.1539 0.1891 0.1099 0.1071 0.1595 0.1344 0.4141 0.1868 0.0002 0.0041 0.0090 0.0124 0.0506 0.0812 0.0669 0.0846 0.6910 12 15 18 23 51 133 250 395 618 0.1321 29.66 4.846 0.5609 121307.0
98300000
95600000000
106000000000000
0.3068 0.3447 0.0442 0.0016 0.1546 0.0133 0.2155 0.0891 0.1482 0.1397 0.1751 0.1708 0.1401 0.1937 0.0636 0.1158 0.0442 0.1223 0.0145 0.1536 0.0006 0.0000 0.0012 0.0004 0.0031 0.0022 0.0115 0.0116 0.0386 0.0343 0.0571 0.0510 0.0451 0.0319 0.0658 0.0520 0.7769 0.8165 0.0007 0.0010 0.0026 0.0022 0.0043 0.0052 0.0155 0.0182 0.0500 0.0581 0.0812 0.0876 0.0644 0.0690 0.0894 0.1000 0.6918 0.6586 0.0002 0.0011 0.0040 0.0169 0.0395 0.0700 0.0579 0.0782 0.7322