High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 977 | 301 | | 13922 | 26863 | 211.1 | 59.41 | 243.85 | 302.54 | 140 | 161 | 177 | 191 | 205 | 221 | 237 | 258 | 290 | 0.0529 | 1421 | 0.517 | 152.46 | 33.12 | 3 | 0.0332 | 462 | 0.0010 | 40.05 | 7.158 | 0.1901 | 48082.9 | 11800000 | 3080000000 | 860000000000 | 0.4554 | 0.1927 | 0.0003 | 0.0000 | 0.0020 | 0.0002 | 0.0126 | 0.0010 | 0.0382 | 0.0033 | 0.1052 | 0.0256 | 0.1779 | 0.0652 | 0.1708 | 0.0702 | 0.1853 | 0.1080 | 0.3078 | 0.7265 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0019 | 0.0001 | 0.0091 | 0.0017 | 0.0405 | 0.0146 | 0.0746 | 0.0338 | 0.0714 | 0.0312 | 0.0998 | 0.0497 | 0.7024 | 0.8688 | 0.0033 | 0.0099 | 0.0092 | 0.0108 | 0.0191 | 0.0381 | 0.0654 | 0.1094 | 0.1325 | 0.1930 | 0.1822 | 0.1872 | 0.1190 | 0.0969 | 0.1457 | 0.1367 | 0.3236 | 0.2179 | 0.0009 | 0.0022 | 0.0066 | 0.0320 | 0.0904 | 0.1306 | 0.1036 | 0.1336 | 0.5001 | 8 | 10 | 14 | 35 | 97 | 203 | 327 | 486 | 702 | 0.0530 | 47.80 | 5.717 | 0.4211 | 150993.0 | 122000000 | 114000000000 | 121000000000000 | 0.4350 | 0.2316 | 0.0406 | 0.0021 | 0.1879 | 0.0150 | 0.2563 | 0.1084 | 0.1660 | 0.1540 | 0.1487 | 0.1826 | 0.0976 | 0.1847 | 0.0579 | 0.1280 | 0.0269 | 0.1004 | 0.0182 | 0.1248 | 0.0001 | 0.0000 | 0.0006 | 0.0003 | 0.0014 | 0.0012 | 0.0074 | 0.0074 | 0.0475 | 0.0377 | 0.0763 | 0.0659 | 0.0613 | 0.0479 | 0.0889 | 0.0735 | 0.7164 | 0.7660 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0025 | 0.0033 | 0.0148 | 0.0202 | 0.0626 | 0.0746 | 0.1137 | 0.1211 | 0.0770 | 0.0770 | 0.1055 | 0.1172 | 0.6229 | 0.5861 | 0.0001 | 0.0008 | 0.0026 | 0.0105 | 0.0553 | 0.0925 | 0.0698 | 0.1031 | 0.6653 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 701 | 856 | | 7996 | 17307 | 193.6 | 58.72 | 164.59 | 174.51 | 125 | 142 | 158 | 171 | 186 | 201 | 219 | 242 | 276 | 0.0699 | 1209 | 0.390 | 189.19 | 52.01 | 6 | 0.0969 | 775 | 0.0004 | 115.49 | 7.998 | 0.1188 | 40941.8 | 9380000 | 2310000000 | 607000000000 | 0.4229 | 0.2241 | 0.0005 | 0.0000 | 0.0018 | 0.0002 | 0.0094 | 0.0009 | 0.0411 | 0.0074 | 0.1168 | 0.0344 | 0.1900 | 0.0791 | 0.1790 | 0.0803 | 0.1954 | 0.1104 | 0.2659 | 0.6873 | 0.0003 | 0.0000 | 0.0010 | 0.0001 | 0.0019 | 0.0003 | 0.0127 | 0.0035 | 0.0368 | 0.0179 | 0.0736 | 0.0397 | 0.0694 | 0.0336 | 0.0989 | 0.0501 | 0.7053 | 0.8549 | 0.0011 | 0.0022 | 0.0058 | 0.0101 | 0.0132 | 0.0348 | 0.0529 | 0.0886 | 0.1242 | 0.1502 | 0.1564 | 0.1973 | 0.1036 | 0.1424 | 0.1416 | 0.1323 | 0.4012 | 0.2422 | 0.0011 | 0.0014 | 0.0067 | 0.0338 | 0.0799 | 0.1053 | 0.1028 | 0.1274 | 0.5416 | 12 | 17 | 27 | 57 | 103 | 156 | 220 | 301 | 416 | 0.0341 | 36.46 | 5.746 | 0.4218 | 57539.3 | 27000000 | 15300000000 | 10100000000000 | 0.6571 | 0.0586 | 0.0542 | 0.0031 | 0.1783 | 0.0167 | 0.2744 | 0.0940 | 0.1826 | 0.1421 | 0.1310 | 0.1851 | 0.0908 | 0.1972 | 0.0521 | 0.1171 | 0.0258 | 0.1158 | 0.0107 | 0.1290 | 0.0001 | 0.0001 | 0.0009 | 0.0003 | 0.0035 | 0.0017 | 0.0141 | 0.0100 | 0.0637 | 0.0508 | 0.1127 | 0.0947 | 0.0879 | 0.0669 | 0.1267 | 0.1070 | 0.5903 | 0.6684 | 0.0002 | 0.0012 | 0.0024 | 0.0030 | 0.0050 | 0.0089 | 0.0260 | 0.0344 | 0.0869 | 0.1000 | 0.1472 | 0.1606 | 0.1046 | 0.1172 | 0.1475 | 0.1538 | 0.4802 | 0.4209 | 0.0006 | 0.0016 | 0.0037 | 0.0192 | 0.0754 | 0.1313 | 0.0961 | 0.1295 | 0.5426 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1221 | 489 | | 5050 | 9168 | 265.7 | 87.85 | 74.96 | 66.43 | 154 | 189 | 212 | 235 | 259 | 289 | 319 | 348 | 383 | 0.0929 | 852 | 1.188 | 99.54 | 33.29 | 1 | 0.0475 | 240 | 0.0005 | 91.15 | 7.822 | 0.1210 | 78333.9 | 25000000 | 8530000000 | 3070000000000 | 0.5037 | 0.1623 | 0.0005 | 0.0005 | 0.0015 | 0.0000 | 0.0109 | 0.0005 | 0.0583 | 0.0055 | 0.1635 | 0.0478 | 0.2362 | 0.1113 | 0.1517 | 0.0894 | 0.1507 | 0.1313 | 0.2268 | 0.6136 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0088 | 0.0024 | 0.0437 | 0.0269 | 0.0917 | 0.0623 | 0.0616 | 0.0423 | 0.0857 | 0.0657 | 0.7070 | 0.8003 | 0.0007 | 0.0031 | 0.0007 | 0.0031 | 0.0080 | 0.0263 | 0.0280 | 0.0789 | 0.0874 | 0.1316 | 0.1475 | 0.1579 | 0.0821 | 0.1300 | 0.1335 | 0.1409 | 0.5120 | 0.3282 | 0.0013 | 0.0021 | 0.0038 | 0.0158 | 0.0554 | 0.1046 | 0.0721 | 0.0900 | 0.6549 | 11 | 16 | 25 | 36 | 53 | 74 | 98 | 128 | 174 | 0.0129 | 12.77 | 5.601 | 0.4237 | 10031.5 | 1760000 | 357000000 | 80500000000 | 0.3984 | 0.2086 | 0.0229 | 0.0012 | 0.0980 | 0.0097 | 0.2408 | 0.0421 | 0.1943 | 0.1069 | 0.1845 | 0.1858 | 0.1176 | 0.1895 | 0.0686 | 0.1656 | 0.0424 | 0.1425 | 0.0310 | 0.1567 | 0.0002 | 0.0004 | 0.0007 | 0.0006 | 0.0047 | 0.0040 | 0.0163 | 0.0144 | 0.0503 | 0.0421 | 0.0822 | 0.0653 | 0.0726 | 0.0593 | 0.0966 | 0.0829 | 0.6764 | 0.7310 | 0.0010 | 0.0016 | 0.0042 | 0.0039 | 0.0065 | 0.0079 | 0.0293 | 0.0347 | 0.0700 | 0.0851 | 0.1059 | 0.1316 | 0.0958 | 0.1056 | 0.1322 | 0.1300 | 0.5550 | 0.4996 | 0.0003 | 0.0030 | 0.0082 | 0.0192 | 0.0604 | 0.0978 | 0.0835 | 0.1173 | 0.6102 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 948 | 602 | | 5482 | 6626 | 431.8 | 96.54 | 133.95 | 147.02 | 321 | 351 | 372 | 394 | 415 | 441 | 472 | 515 | 567 | 0.1180 | 782 | 1.222 | 113.85 | 42.45 | 1 | 0.0520 | 285 | 0.0009 | 43.04 | 7.265 | 0.1744 | 195782.0 | 93200000 | 46500000000 | 24300000000000 | 0.4072 | 0.2460 | 0.0012 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0145 | 0.0012 | 0.0707 | 0.0208 | 0.1385 | 0.0387 | 0.1405 | 0.0363 | 0.1657 | 0.0562 | 0.4649 | 0.8469 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0056 | 0.0004 | 0.0357 | 0.0158 | 0.0655 | 0.0214 | 0.0748 | 0.0204 | 0.0919 | 0.0339 | 0.7240 | 0.9081 | 0.0029 | 0.0035 | 0.0029 | 0.0035 | 0.0095 | 0.0141 | 0.0475 | 0.0742 | 0.0846 | 0.1696 | 0.1454 | 0.2155 | 0.1055 | 0.1060 | 0.1084 | 0.1095 | 0.4933 | 0.3039 | 0.0021 | 0.0008 | 0.0119 | 0.0296 | 0.0716 | 0.1067 | 0.0809 | 0.0949 | 0.6014 | 11 | 15 | 23 | 44 | 79 | 120 | 169 | 238 | 356 | 0.0197 | 24.70 | 5.729 | 0.4245 | 39552.5 | 16000000 | 7850000000 | 4460000000000 | 0.4462 | 0.1848 | 0.0329 | 0.0007 | 0.1368 | 0.0059 | 0.2053 | 0.0553 | 0.2026 | 0.1211 | 0.1539 | 0.1895 | 0.1250 | 0.1914 | 0.0645 | 0.1303 | 0.0500 | 0.1375 | 0.0289 | 0.1684 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0012 | 0.0119 | 0.0055 | 0.0633 | 0.0525 | 0.0857 | 0.0756 | 0.0689 | 0.0619 | 0.1147 | 0.1026 | 0.6548 | 0.7008 | 0.0010 | 0.0017 | 0.0010 | 0.0017 | 0.0048 | 0.0039 | 0.0162 | 0.0231 | 0.0796 | 0.0732 | 0.0977 | 0.1082 | 0.0881 | 0.0890 | 0.1148 | 0.1104 | 0.5970 | 0.5887 | 0.0004 | 0.0000 | 0.0029 | 0.0139 | 0.0644 | 0.1076 | 0.0770 | 0.1129 | 0.6209 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1055 | 275 | | 6493 | 11263 | 218.6 | 48.26 | 203.76 | 248.93 | 160 | 175 | 188 | 202 | 213 | 228 | 242 | 260 | 284 | 0.0805 | 907 | 1.214 | 109.13 | 46.40 | 1 | 0.0445 | 289 | 0.0010 | 41.92 | 7.174 | 0.1818 | 50116.4 | 12000000 | 3010000000 | 787000000000 | 0.4497 | 0.2024 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0071 | 0.0008 | 0.0185 | 0.0023 | 0.0843 | 0.0181 | 0.1430 | 0.0392 | 0.1440 | 0.0382 | 0.1793 | 0.0581 | 0.4215 | 0.8433 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0033 | 0.0006 | 0.0078 | 0.0012 | 0.0341 | 0.0120 | 0.0614 | 0.0246 | 0.0581 | 0.0156 | 0.0872 | 0.0283 | 0.7468 | 0.9177 | 0.0041 | 0.0101 | 0.0139 | 0.0270 | 0.0204 | 0.0642 | 0.0736 | 0.1182 | 0.1177 | 0.1959 | 0.1586 | 0.1791 | 0.1267 | 0.1115 | 0.1415 | 0.1149 | 0.3434 | 0.1791 | 0.0013 | 0.0037 | 0.0043 | 0.0266 | 0.0817 | 0.1116 | 0.0986 | 0.1305 | 0.5418 | 15 | 19 | 27 | 46 | 82 | 147 | 253 | 388 | 594 | 0.0226 | 54.69 | 5.986 | 0.4245 | 103479.0 | 70800000 | 56800000000 | 51000000000000 | 0.5176 | 0.1383 | 0.0392 | 0.0017 | 0.1105 | 0.0111 | 0.2280 | 0.0589 | 0.2245 | 0.1100 | 0.1425 | 0.1800 | 0.1140 | 0.2156 | 0.0784 | 0.1367 | 0.0439 | 0.1144 | 0.0190 | 0.1717 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0016 | 0.0012 | 0.0128 | 0.0072 | 0.0372 | 0.0364 | 0.0763 | 0.0706 | 0.0547 | 0.0455 | 0.0772 | 0.0701 | 0.7402 | 0.7678 | 0.0006 | 0.0007 | 0.0006 | 0.0000 | 0.0020 | 0.0030 | 0.0121 | 0.0115 | 0.0506 | 0.0603 | 0.0917 | 0.1121 | 0.0697 | 0.0752 | 0.0975 | 0.1124 | 0.6752 | 0.6248 | 0.0000 | 0.0005 | 0.0018 | 0.0083 | 0.0458 | 0.0871 | 0.0564 | 0.0843 | 0.7159 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 488 | | 1658 | 7515 | 661.2 | 127.45 | 21.12 | 72.35 | 472 | 534 | 588 | 636 | 672 | 708 | 749 | 791 | 831 | 0.0896 | 673 | 1.056 | 79.26 | 20.40 | 1 | 0.1128 | 187 | 0.0037 | 8.63 | 5.897 | 0.3770 | 453371.0 | 321000000 | 233000000000 | 172000000000000 | 0.3992 | 0.2328 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0098 | 0.0018 | 0.0479 | 0.0231 | 0.0685 | 0.0358 | 0.0607 | 0.0219 | 0.0881 | 0.0328 | 0.7202 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0018 | 0.0283 | 0.0231 | 0.0358 | 0.0358 | 0.0253 | 0.0219 | 0.0365 | 0.0328 | 0.8718 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0000 | 0.0344 | 0.0000 | 0.0531 | 0.0000 | 0.0531 | 0.0000 | 0.0688 | 0.0000 | 0.1000 | 0.0000 | 0.6781 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0135 | 0.0270 | 0.0529 | 0.0450 | 0.0541 | 0.8018 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 12 | 17 | 0.1063 | 2.38 | 1.499 | 0.4250 | 5680.0 | 3330000 | 2380000000 | 1890000000000 | 0.4909 | 0.1207 | 0.0780 | 0.0610 | 0.2110 | 0.0749 | 0.2844 | 0.0999 | 0.2661 | 0.1207 | 0.0826 | 0.1914 | 0.0505 | 0.1692 | 0.0092 | 0.0874 | 0.0138 | 0.0707 | 0.0046 | 0.1248 | 0.0181 | 0.0352 | 0.0233 | 0.0424 | 0.0194 | 0.0488 | 0.0440 | 0.0456 | 0.0660 | 0.0697 | 0.0699 | 0.0689 | 0.0621 | 0.0817 | 0.0776 | 0.0961 | 0.6197 | 0.5116 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0054 | 0.0000 | 0.0090 | 0.0189 | 0.0667 | 0.0682 | 0.1189 | 0.0928 | 0.0360 | 0.0625 | 0.0811 | 0.0795 | 0.6829 | 0.6761 | 0.0016 | 0.0064 | 0.0096 | 0.0305 | 0.0595 | 0.0691 | 0.0740 | 0.0804 | 0.6688 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 575 | | 6042 | 12072 | 101.1 | 29.15 | 201.53 | 223.69 | 69 | 77 | 84 | 91 | 97 | 103 | 110 | 120 | 139 | 0.0696 | 840 | 0.813 | 79.88 | 25.94 | 1 | 0.0386 | 233 | 0.0015 | 30.07 | 6.806 | 0.2198 | 11069.0 | 1320000 | 170000000 | 23900000000 | 0.4862 | 0.1865 | 0.0018 | 0.0002 | 0.0053 | 0.0006 | 0.0143 | 0.0023 | 0.0289 | 0.0069 | 0.0949 | 0.0296 | 0.1530 | 0.0590 | 0.1434 | 0.0611 | 0.1755 | 0.0846 | 0.3829 | 0.7558 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0005 | 0.0109 | 0.0028 | 0.0454 | 0.0160 | 0.0803 | 0.0329 | 0.0748 | 0.0325 | 0.1071 | 0.0463 | 0.6782 | 0.8690 | 0.0043 | 0.0000 | 0.0017 | 0.0123 | 0.0112 | 0.0334 | 0.0543 | 0.0598 | 0.1422 | 0.1652 | 0.1716 | 0.1845 | 0.1112 | 0.1037 | 0.1362 | 0.1564 | 0.3672 | 0.2847 | 0.0008 | 0.0053 | 0.0162 | 0.0442 | 0.0797 | 0.1330 | 0.1035 | 0.1300 | 0.4873 | 18 | 30 | 47 | 67 | 108 | 171 | 253 | 356 | 517 | 0.0128 | 34.28 | 6.003 | 0.4255 | 90647.1 | 57700000 | 45300000000 | 41800000000000 | 0.5238 | 0.1388 | 0.0299 | 0.0012 | 0.1106 | 0.0112 | 0.2542 | 0.0630 | 0.1719 | 0.1064 | 0.1356 | 0.1694 | 0.1203 | 0.2041 | 0.0759 | 0.1291 | 0.0581 | 0.1283 | 0.0436 | 0.1873 | 0.0002 | 0.0003 | 0.0012 | 0.0009 | 0.0024 | 0.0014 | 0.0120 | 0.0077 | 0.0503 | 0.0456 | 0.0918 | 0.0772 | 0.0637 | 0.0548 | 0.0892 | 0.0894 | 0.6892 | 0.7227 | 0.0008 | 0.0000 | 0.0005 | 0.0016 | 0.0040 | 0.0062 | 0.0171 | 0.0230 | 0.0656 | 0.0792 | 0.1207 | 0.1321 | 0.0874 | 0.0879 | 0.1189 | 0.1252 | 0.5850 | 0.5447 | 0.0005 | 0.0016 | 0.0021 | 0.0115 | 0.0607 | 0.1004 | 0.0736 | 0.1068 | 0.6429 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1301 | 922 | | 1366 | 2845 | 88.3 | 15.42 | 119.74 | 63.45 | 71 | 75 | 79 | 82 | 86 | 89 | 94 | 101 | 110 | 0.1547 | 440 | 0.932 | 89.36 | 30.02 | 1 | 0.1808 | 247 | 0.0068 | 9.05 | 5.271 | 0.3306 | 8028.3 | 753530 | 73100000 | 7320000000 | 0.4490 | 0.1982 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0164 | 0.0023 | 0.0733 | 0.0233 | 0.1485 | 0.0593 | 0.1736 | 0.0360 | 0.2343 | 0.0765 | 0.3481 | 0.8027 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0081 | 0.0022 | 0.0422 | 0.0205 | 0.0755 | 0.0490 | 0.0739 | 0.0190 | 0.1226 | 0.0381 | 0.6761 | 0.8712 | 0.0256 | 0.0303 | 0.0615 | 0.1515 | 0.0308 | 0.1515 | 0.1538 | 0.1212 | 0.1538 | 0.1515 | 0.1590 | 0.2121 | 0.1385 | 0.0909 | 0.1590 | 0.0606 | 0.1179 | 0.0303 | 0.0065 | 0.0114 | 0.0244 | 0.0603 | 0.0945 | 0.1222 | 0.1596 | 0.1417 | 0.3795 | 46 | 63 | 81 | 98 | 113 | 127 | 144 | 167 | 202 | 0.0075 | 7.31 | 5.265 | 0.4258 | 18362.3 | 3410000 | 742000000 | 186000000000 | 0.5900 | 0.1093 | 0.0045 | 0.0032 | 0.0465 | 0.0127 | 0.1213 | 0.0222 | 0.1122 | 0.0565 | 0.1655 | 0.1016 | 0.1565 | 0.1479 | 0.1565 | 0.1384 | 0.1168 | 0.1625 | 0.1202 | 0.3549 | 0.0000 | 0.0019 | 0.0063 | 0.0042 | 0.0091 | 0.0070 | 0.0223 | 0.0164 | 0.0566 | 0.0529 | 0.1189 | 0.0791 | 0.0840 | 0.0669 | 0.1309 | 0.0993 | 0.5720 | 0.6723 | 0.0046 | 0.0107 | 0.0092 | 0.0143 | 0.0288 | 0.0481 | 0.0714 | 0.1016 | 0.1429 | 0.1373 | 0.1705 | 0.1836 | 0.1244 | 0.1390 | 0.1244 | 0.1622 | 0.3237 | 0.2032 | 0.0000 | 0.0101 | 0.0155 | 0.0364 | 0.1006 | 0.1509 | 0.1223 | 0.1409 | 0.4234 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1003 | 529 | | 2853 | 9441 | 157.4 | 32.63 | 102.01 | 102.33 | 118 | 129 | 138 | 146 | 154 | 163 | 173 | 186 | 203 | 0.0660 | 623 | 0.979 | 160.03 | 54.33 | 2 | 0.1497 | 427 | 0.0019 | 22.36 | 6.477 | 0.2304 | 25843.1 | 4420000 | 785000000 | 145000000000 | 0.4460 | 0.2072 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0192 | 0.0004 | 0.0719 | 0.0167 | 0.1561 | 0.0452 | 0.1556 | 0.0440 | 0.1859 | 0.0766 | 0.4081 | 0.8172 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0079 | 0.0004 | 0.0339 | 0.0128 | 0.0715 | 0.0313 | 0.0619 | 0.0174 | 0.0983 | 0.0366 | 0.7251 | 0.9015 | 0.0058 | 0.0182 | 0.0136 | 0.0636 | 0.0312 | 0.1091 | 0.0546 | 0.1364 | 0.1598 | 0.2091 | 0.1598 | 0.1636 | 0.1326 | 0.1091 | 0.1501 | 0.0727 | 0.2924 | 0.1182 | 0.0022 | 0.0022 | 0.0082 | 0.0461 | 0.0848 | 0.1413 | 0.1048 | 0.1361 | 0.4743 | 11 | 16 | 29 | 45 | 66 | 93 | 129 | 176 | 245 | 0.0152 | 19.08 | 5.619 | 0.4258 | 20875.8 | 5920000 | 2050000000 | 824000000000 | 0.6242 | 0.0881 | 0.0390 | 0.0034 | 0.1453 | 0.0111 | 0.2356 | 0.0610 | 0.1887 | 0.1245 | 0.1532 | 0.1987 | 0.1098 | 0.1906 | 0.0691 | 0.1394 | 0.0452 | 0.1275 | 0.0142 | 0.1437 | 0.0005 | 0.0002 | 0.0017 | 0.0008 | 0.0036 | 0.0041 | 0.0167 | 0.0119 | 0.0708 | 0.0582 | 0.1106 | 0.0877 | 0.0886 | 0.0769 | 0.1254 | 0.1103 | 0.5821 | 0.6499 | 0.0013 | 0.0008 | 0.0027 | 0.0032 | 0.0103 | 0.0122 | 0.0279 | 0.0363 | 0.0920 | 0.1137 | 0.1411 | 0.1512 | 0.1159 | 0.1204 | 0.1388 | 0.1524 | 0.4699 | 0.4098 | 0.0011 | 0.0034 | 0.0062 | 0.0220 | 0.0772 | 0.1297 | 0.1020 | 0.1334 | 0.5249 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 563 | 523 | | 7584 | 13597 | 292.9 | 83.06 | 182.75 | 174.84 | 193 | 209 | 226 | 248 | 286 | 322 | 349 | 375 | 408 | 0.0785 | 1067 | 1.101 | 127.77 | 42.45 | 1 | 0.0407 | 309 | 0.0016 | 18.42 | 6.833 | 0.3003 | 92706.4 | 31400000 | 11200000000 | 4180000000000 | 0.4037 | 0.2427 | 0.0029 | 0.0000 | 0.0068 | 0.0012 | 0.0184 | 0.0023 | 0.0417 | 0.0059 | 0.0763 | 0.0230 | 0.1000 | 0.0516 | 0.1051 | 0.0428 | 0.1263 | 0.0614 | 0.5225 | 0.8120 | 0.0010 | 0.0000 | 0.0022 | 0.0011 | 0.0026 | 0.0007 | 0.0070 | 0.0022 | 0.0191 | 0.0112 | 0.0291 | 0.0256 | 0.0275 | 0.0134 | 0.0388 | 0.0299 | 0.8726 | 0.9160 | 0.0014 | 0.0000 | 0.0023 | 0.0000 | 0.0073 | 0.0000 | 0.0200 | 0.0000 | 0.0514 | 0.0000 | 0.0906 | 0.0000 | 0.0915 | 0.0000 | 0.1138 | 0.0000 | 0.6218 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0055 | 0.0191 | 0.0372 | 0.0372 | 0.0563 | 0.8437 | 21 | 37 | 61 | 91 | 127 | 171 | 226 | 307 | 431 | 0.0098 | 23.73 | 6.012 | 0.4274 | 63963.5 | 31000000 | 18200000000 | 12200000000000 | 0.4970 | 0.1734 | 0.0146 | 0.0008 | 0.0690 | 0.0059 | 0.1458 | 0.0403 | 0.1437 | 0.0687 | 0.1813 | 0.1390 | 0.1557 | 0.1647 | 0.0967 | 0.1352 | 0.0810 | 0.1280 | 0.1123 | 0.3175 | 0.0002 | 0.0000 | 0.0006 | 0.0014 | 0.0034 | 0.0032 | 0.0156 | 0.0128 | 0.0523 | 0.0433 | 0.0827 | 0.0651 | 0.0658 | 0.0553 | 0.0969 | 0.0768 | 0.6825 | 0.7421 | 0.0007 | 0.0011 | 0.0009 | 0.0049 | 0.0082 | 0.0066 | 0.0238 | 0.0255 | 0.0714 | 0.0887 | 0.1100 | 0.1319 | 0.0872 | 0.0887 | 0.1249 | 0.1379 | 0.5728 | 0.5147 | 0.0002 | 0.0029 | 0.0057 | 0.0176 | 0.0629 | 0.0975 | 0.0805 | 0.1129 | 0.6198 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 780 | 834 | | 6318 | 19340 | 609.7 | 114.55 | 120.41 | 134.66 | 470 | 509 | 540 | 570 | 600 | 630 | 663 | 704 | 767 | 0.0498 | 964 | 0.726 | 86.01 | 16.03 | 1 | 0.0298 | 188 | 0.0006 | 70.14 | 7.636 | 0.1483 | 384808.0 | 251000000 | 169000000000 | 118000000000000 | 0.4102 | 0.2380 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0085 | 0.0016 | 0.0475 | 0.0150 | 0.0953 | 0.0289 | 0.1183 | 0.0271 | 0.1343 | 0.0400 | 0.5943 | 0.8873 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0039 | 0.0005 | 0.0245 | 0.0116 | 0.0479 | 0.0198 | 0.0540 | 0.0127 | 0.0670 | 0.0219 | 0.8018 | 0.9335 | 0.0021 | 0.0054 | 0.0053 | 0.0109 | 0.0253 | 0.0489 | 0.0654 | 0.1522 | 0.1139 | 0.2011 | 0.1414 | 0.1902 | 0.0876 | 0.1467 | 0.1382 | 0.1250 | 0.4209 | 0.1196 | 0.0017 | 0.0024 | 0.0051 | 0.0330 | 0.0633 | 0.1113 | 0.1144 | 0.1208 | 0.5480 | 10 | 12 | 16 | 32 | 64 | 109 | 162 | 224 | 319 | 0.0289 | 26.76 | 5.663 | 0.4276 | 32630.8 | 11900000 | 5250000000 | 2670000000000 | 0.4590 | 0.1836 | 0.0336 | 0.0024 | 0.1633 | 0.0091 | 0.2748 | 0.0760 | 0.1537 | 0.1425 | 0.1526 | 0.1964 | 0.1089 | 0.2073 | 0.0699 | 0.1294 | 0.0304 | 0.1211 | 0.0128 | 0.1158 | 0.0004 | 0.0001 | 0.0014 | 0.0003 | 0.0024 | 0.0013 | 0.0079 | 0.0078 | 0.0464 | 0.0377 | 0.0825 | 0.0694 | 0.0683 | 0.0566 | 0.0985 | 0.0850 | 0.6922 | 0.7418 | 0.0002 | 0.0005 | 0.0017 | 0.0016 | 0.0039 | 0.0052 | 0.0136 | 0.0186 | 0.0639 | 0.0748 | 0.1128 | 0.1253 | 0.0862 | 0.0934 | 0.1154 | 0.1298 | 0.6023 | 0.5508 | 0.0001 | 0.0010 | 0.0030 | 0.0108 | 0.0575 | 0.0944 | 0.0796 | 0.1088 | 0.6448 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 688 | 324 | | 13758 | 21485 | 122.6 | 40.36 | 202.58 | 231.30 | 76 | 90 | 98 | 107 | 117 | 128 | 141 | 156 | 178 | 0.0872 | 1874 | 0.692 | 86.83 | 17.09 | 4 | 0.0151 | 208 | 0.0009 | 37.58 | 7.369 | 0.2047 | 16661.6 | 2480000 | 400000000 | 69100000000 | 0.4692 | 0.2051 | 0.0024 | 0.0004 | 0.0062 | 0.0006 | 0.0139 | 0.0027 | 0.0405 | 0.0084 | 0.0991 | 0.0326 | 0.1598 | 0.0715 | 0.1633 | 0.0626 | 0.1771 | 0.0877 | 0.3378 | 0.7336 | 0.0011 | 0.0002 | 0.0029 | 0.0003 | 0.0047 | 0.0010 | 0.0145 | 0.0048 | 0.0370 | 0.0172 | 0.0555 | 0.0390 | 0.0585 | 0.0291 | 0.0729 | 0.0411 | 0.7528 | 0.8673 | 0.0020 | 0.0037 | 0.0072 | 0.0067 | 0.0133 | 0.0209 | 0.0372 | 0.0491 | 0.0847 | 0.1098 | 0.1175 | 0.1589 | 0.0893 | 0.1141 | 0.1233 | 0.1387 | 0.5255 | 0.3982 | 0.0010 | 0.0026 | 0.0073 | 0.0221 | 0.0578 | 0.0893 | 0.0766 | 0.1021 | 0.6413 | 15 | 20 | 31 | 57 | 109 | 182 | 259 | 358 | 545 | 0.0237 | 41.98 | 5.971 | 0.4277 | 94535.6 | 60700000 | 46900000000 | 41300000000000 | 0.5071 | 0.1526 | 0.0324 | 0.0022 | 0.1222 | 0.0156 | 0.1953 | 0.0725 | 0.1804 | 0.1085 | 0.1681 | 0.1619 | 0.1340 | 0.1825 | 0.0858 | 0.1314 | 0.0495 | 0.1367 | 0.0324 | 0.1888 | 0.0001 | 0.0005 | 0.0017 | 0.0015 | 0.0035 | 0.0027 | 0.0122 | 0.0106 | 0.0577 | 0.0494 | 0.0901 | 0.0778 | 0.0671 | 0.0552 | 0.0932 | 0.0791 | 0.6743 | 0.7233 | 0.0003 | 0.0010 | 0.0028 | 0.0034 | 0.0068 | 0.0100 | 0.0237 | 0.0359 | 0.0811 | 0.0934 | 0.1246 | 0.1344 | 0.0910 | 0.0879 | 0.1214 | 0.1091 | 0.5482 | 0.5250 | 0.0005 | 0.0019 | 0.0048 | 0.0175 | 0.0673 | 0.1061 | 0.0788 | 0.1115 | 0.6117 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1140 | 800 | | 415 | 10014 | 37.5 | 8.37 | 298.79 | 356.44 | 26 | 30 | 32 | 35 | 37 | 40 | 42 | 45 | 48 | 0.0520 | 521 | 0.700 | 202.20 | 35.61 | 2 | 1.1663 | 484 | 0.0170 | 4.33 | 4.301 | 0.4484 | 1479.7 | 60857.1 | 2600000 | 115000000 | 0.3546 | 0.2708 | 0.0000 | 0.0000 | 0.0083 | 0.0000 | 0.0373 | 0.0025 | 0.1037 | 0.0176 | 0.2241 | 0.0529 | 0.2033 | 0.0856 | 0.1867 | 0.1058 | 0.1743 | 0.1738 | 0.0622 | 0.5617 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0127 | 0.0025 | 0.0538 | 0.0173 | 0.0854 | 0.0519 | 0.0918 | 0.0765 | 0.1076 | 0.0914 | 0.1424 | 0.1136 | 0.5032 | 0.6469 | 0.0533 | 0.2500 | 0.0800 | 0.0000 | 0.0533 | 0.0000 | 0.2000 | 0.3750 | 0.1600 | 0.2500 | 0.1467 | 0.1250 | 0.2133 | 0.0000 | 0.0533 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0291 | 0.0825 | 0.1311 | 0.1602 | 0.1408 | 0.1748 | 0.2816 | 16 | 19 | 26 | 56 | 134 | 250 | 397 | 574 | 843 | 0.0362 | 50.93 | 5.899 | 0.4283 | 216312.0 | 203000000 | 220000000000 | 261000000000000 | 0.5151 | 0.1616 | 0.0713 | 0.0006 | 0.1940 | 0.0107 | 0.2691 | 0.1146 | 0.2078 | 0.1740 | 0.1352 | 0.1960 | 0.0701 | 0.1829 | 0.0250 | 0.1140 | 0.0163 | 0.1146 | 0.0113 | 0.0926 | 0.0002 | 0.0000 | 0.0002 | 0.0009 | 0.0022 | 0.0018 | 0.0115 | 0.0112 | 0.0583 | 0.0497 | 0.0937 | 0.0790 | 0.0718 | 0.0645 | 0.0976 | 0.0919 | 0.6644 | 0.7012 | 0.0003 | 0.0007 | 0.0018 | 0.0045 | 0.0055 | 0.0111 | 0.0210 | 0.0236 | 0.0735 | 0.0748 | 0.1104 | 0.1219 | 0.0921 | 0.0890 | 0.1052 | 0.1126 | 0.5902 | 0.5618 | 0.0003 | 0.0005 | 0.0027 | 0.0156 | 0.0648 | 0.1058 | 0.0826 | 0.1017 | 0.6260 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1111 | 218 | | 2639 | 15470 | 519.2 | 295.40 | 7.24 | 2.89 | 158 | 199 | 267 | 362 | 461 | 629 | 752 | 861 | 946 | 0.0584 | 904 | 1.018 | 61.29 | 17.26 | 1 | 0.0561 | 148 | 0.0024 | 14.54 | 6.516 | 0.3332 | 356819.0 | 281000000 | 236000000000 | 206000000000000 | 0.3341 | 0.2839 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0102 | 0.0024 | 0.0332 | 0.0071 | 0.1969 | 0.0756 | 0.2123 | 0.1263 | 0.1637 | 0.0862 | 0.1867 | 0.1098 | 0.1944 | 0.5927 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0012 | 0.0014 | 0.0018 | 0.0254 | 0.0257 | 0.0357 | 0.0293 | 0.0254 | 0.0246 | 0.0460 | 0.0334 | 0.8640 | 0.8841 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0019 | 0.0058 | 0.0319 | 0.0255 | 0.0432 | 0.0638 | 0.0244 | 0.0290 | 0.0413 | 0.0348 | 0.8573 | 0.8399 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0262 | 0.0467 | 0.0213 | 0.0344 | 0.8705 | 3 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 11 | 0.1427 | 0.45 | 0.999 | 0.4303 | 60.8 | 577.971 | 6348.95 | 88018.5 | 0.4997 | 0.1587 | 0.0222 | 0.0021 | 0.0836 | 0.0094 | 0.1754 | 0.0371 | 0.2398 | 0.0855 | 0.2237 | 0.1719 | 0.1606 | 0.2362 | 0.0727 | 0.2550 | 0.0202 | 0.1567 | 0.0017 | 0.0461 | 0.0016 | 0.0002 | 0.0068 | 0.0010 | 0.0283 | 0.0046 | 0.0631 | 0.0161 | 0.1191 | 0.0465 | 0.1675 | 0.1004 | 0.2085 | 0.1888 | 0.2349 | 0.2956 | 0.1701 | 0.3468 | 0.0733 | 0.1314 | 0.1319 | 0.2046 | 0.1568 | 0.2008 | 0.1465 | 0.1602 | 0.1442 | 0.1368 | 0.1434 | 0.0882 | 0.1027 | 0.0454 | 0.0718 | 0.0227 | 0.0294 | 0.0099 | 0.0130 | 0.0314 | 0.0618 | 0.0977 | 0.1424 | 0.1625 | 0.1874 | 0.1808 | 0.1230 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1049 | 621 | | 590 | 4448 | 85.8 | 21.32 | 144.11 | 133.60 | 56 | 64 | 73 | 81 | 87 | 93 | 99 | 106 | 114 | 0.1034 | 460 | 0.497 | 89.47 | 17.12 | 2 | 0.4254 | 251 | 0.0059 | 8.91 | 5.340 | 0.3127 | 7819.9 | 748619 | 74600000 | 7680000000 | 0.5406 | 0.1228 | 0.0066 | 0.0000 | 0.0197 | 0.0037 | 0.0656 | 0.0019 | 0.1016 | 0.0335 | 0.1311 | 0.0764 | 0.2557 | 0.1676 | 0.1213 | 0.0950 | 0.1279 | 0.1639 | 0.1705 | 0.4581 | 0.0000 | 0.0000 | 0.0023 | 0.0018 | 0.0023 | 0.0018 | 0.0227 | 0.0161 | 0.0975 | 0.0698 | 0.2245 | 0.1592 | 0.0998 | 0.0823 | 0.1678 | 0.1485 | 0.3832 | 0.5206 | 0.0000 | 0.0000 | 0.0074 | 0.0909 | 0.0662 | 0.1818 | 0.1103 | 0.2273 | 0.1838 | 0.3636 | 0.2721 | 0.0455 | 0.1176 | 0.0909 | 0.0809 | 0.0000 | 0.1618 | 0.0000 | 0.0032 | 0.0130 | 0.0260 | 0.0747 | 0.1494 | 0.1851 | 0.1071 | 0.1558 | 0.2857 | 25 | 39 | 55 | 74 | 98 | 130 | 170 | 228 | 340 | 0.0100 | 16.93 | 5.669 | 0.4305 | 38612.5 | 14500000 | 6620000000 | 3390000000000 | 0.5378 | 0.1265 | 0.0156 | 0.0023 | 0.0845 | 0.0068 | 0.1831 | 0.0288 | 0.1815 | 0.0788 | 0.1800 | 0.1455 | 0.1315 | 0.1856 | 0.0767 | 0.1667 | 0.0610 | 0.1439 | 0.0861 | 0.2417 | 0.0010 | 0.0013 | 0.0036 | 0.0025 | 0.0051 | 0.0033 | 0.0159 | 0.0134 | 0.0568 | 0.0473 | 0.0967 | 0.0854 | 0.0747 | 0.0703 | 0.0988 | 0.1000 | 0.6474 | 0.6766 | 0.0000 | 0.0037 | 0.0038 | 0.0019 | 0.0198 | 0.0131 | 0.0243 | 0.0411 | 0.0654 | 0.0626 | 0.1209 | 0.1280 | 0.0928 | 0.0888 | 0.1042 | 0.1271 | 0.5688 | 0.5336 | 0.0006 | 0.0000 | 0.0112 | 0.0262 | 0.0611 | 0.1185 | 0.0855 | 0.1017 | 0.5951 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 686 | 625 | | 6653 | 21616 | 335.3 | 63.66 | 169.19 | 212.41 | 264 | 281 | 295 | 309 | 325 | 342 | 362 | 385 | 425 | 0.0403 | 871 | 1.098 | 108.24 | 36.69 | 1 | 0.0412 | 274 | 0.0007 | 66.56 | 7.535 | 0.1518 | 116505.0 | 42000000 | 15700000000 | 6090000000000 | 0.4550 | 0.1972 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0011 | 0.0474 | 0.0135 | 0.1064 | 0.0297 | 0.1104 | 0.0278 | 0.1437 | 0.0363 | 0.5825 | 0.8914 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0239 | 0.0090 | 0.0529 | 0.0155 | 0.0543 | 0.0084 | 0.0731 | 0.0141 | 0.7917 | 0.9529 | 0.0030 | 0.0000 | 0.0120 | 0.0243 | 0.0200 | 0.0208 | 0.0430 | 0.1250 | 0.1289 | 0.1736 | 0.1548 | 0.2153 | 0.1009 | 0.1215 | 0.1419 | 0.1458 | 0.3956 | 0.1736 | 0.0017 | 0.0010 | 0.0113 | 0.0284 | 0.0825 | 0.1140 | 0.1062 | 0.1308 | 0.5240 | 11 | 13 | 15 | 21 | 59 | 135 | 223 | 332 | 480 | 0.0461 | 55.65 | 5.697 | 0.4308 | 73741.6 | 43100000 | 29900000000 | 23400000000000 | 0.4089 | 0.2338 | 0.0463 | 0.0015 | 0.1935 | 0.0167 | 0.2745 | 0.1152 | 0.1777 | 0.1388 | 0.1357 | 0.1962 | 0.0901 | 0.1912 | 0.0542 | 0.1307 | 0.0213 | 0.1096 | 0.0067 | 0.1001 | 0.0001 | 0.0001 | 0.0014 | 0.0005 | 0.0035 | 0.0017 | 0.0088 | 0.0064 | 0.0446 | 0.0382 | 0.0850 | 0.0684 | 0.0604 | 0.0514 | 0.0846 | 0.0704 | 0.7116 | 0.7629 | 0.0009 | 0.0006 | 0.0029 | 0.0029 | 0.0063 | 0.0060 | 0.0129 | 0.0147 | 0.0599 | 0.0658 | 0.1035 | 0.1203 | 0.0786 | 0.0886 | 0.1056 | 0.1095 | 0.6295 | 0.5914 | 0.0001 | 0.0022 | 0.0036 | 0.0127 | 0.0496 | 0.0976 | 0.0729 | 0.0936 | 0.6678 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 384 | | 3864 | 10644 | 549.9 | 111.66 | 119.69 | 118.07 | 401 | 445 | 482 | 515 | 547 | 581 | 614 | 651 | 699 | 0.0750 | 798 | 1.029 | 90.48 | 35.85 | 1 | 0.0663 | 256 | 0.0007 | 70.72 | 7.491 | 0.1370 | 314839.0 | 187000000 | 115000000000 | 72500000000000 | 0.4423 | 0.2000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0000 | 0.0131 | 0.0027 | 0.0668 | 0.0158 | 0.1439 | 0.0363 | 0.1447 | 0.0328 | 0.1681 | 0.0507 | 0.4596 | 0.8617 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0021 | 0.0277 | 0.0136 | 0.0621 | 0.0288 | 0.0535 | 0.0207 | 0.0701 | 0.0298 | 0.7804 | 0.9050 | 0.0029 | 0.0519 | 0.0114 | 0.0390 | 0.0157 | 0.0390 | 0.0672 | 0.1818 | 0.1502 | 0.2338 | 0.1788 | 0.1948 | 0.1288 | 0.1169 | 0.1431 | 0.0519 | 0.3019 | 0.0909 | 0.0000 | 0.0010 | 0.0037 | 0.0199 | 0.0659 | 0.1141 | 0.0795 | 0.1141 | 0.6018 | 11 | 15 | 23 | 44 | 81 | 122 | 165 | 219 | 293 | 0.0192 | 16.46 | 5.675 | 0.4317 | 28266.0 | 8580000 | 3000000000 | 1160000000000 | 0.4622 | 0.1810 | 0.0320 | 0.0021 | 0.1652 | 0.0111 | 0.2654 | 0.0848 | 0.1446 | 0.1330 | 0.1611 | 0.2072 | 0.1002 | 0.1734 | 0.0666 | 0.1199 | 0.0411 | 0.1273 | 0.0238 | 0.1413 | 0.0004 | 0.0004 | 0.0002 | 0.0004 | 0.0026 | 0.0020 | 0.0100 | 0.0065 | 0.0573 | 0.0464 | 0.0915 | 0.0770 | 0.0713 | 0.0525 | 0.1045 | 0.0919 | 0.6622 | 0.7230 | 0.0003 | 0.0006 | 0.0019 | 0.0016 | 0.0054 | 0.0048 | 0.0200 | 0.0279 | 0.0764 | 0.0901 | 0.1300 | 0.1487 | 0.0978 | 0.0983 | 0.1230 | 0.1376 | 0.5451 | 0.4903 | 0.0005 | 0.0016 | 0.0023 | 0.0137 | 0.0615 | 0.1121 | 0.0896 | 0.1246 | 0.5942 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 457 | 212 | | 6322 | 18147 | 382.8 | 44.78 | 238.77 | 294.82 | 326 | 348 | 362 | 373 | 384 | 395 | 406 | 419 | 439 | 0.0600 | 1088 | 1.215 | 99.36 | 36.50 | 1 | 0.0386 | 244 | 0.0018 | 29.68 | 6.658 | 0.2214 | 148564.0 | 58400000 | 23200000000 | 9350000000000 | 0.4200 | 0.2268 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0033 | 0.0005 | 0.0198 | 0.0108 | 0.0385 | 0.0209 | 0.0480 | 0.0104 | 0.0811 | 0.0223 | 0.8084 | 0.9351 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0015 | 0.0005 | 0.0136 | 0.0108 | 0.0260 | 0.0209 | 0.0246 | 0.0104 | 0.0395 | 0.0223 | 0.8947 | 0.9351 | 0.0536 | 0.0000 | 0.0421 | 0.0000 | 0.0651 | 0.0000 | 0.1303 | 0.0000 | 0.1418 | 0.0000 | 0.2222 | 0.0000 | 0.1188 | 0.0000 | 0.1341 | 0.0000 | 0.0920 | 0.0000 | 0.0012 | 0.0049 | 0.0132 | 0.0292 | 0.0679 | 0.1075 | 0.1161 | 0.1588 | 0.5012 | 17 | 22 | 29 | 46 | 89 | 180 | 301 | 457 | 675 | 0.0295 | 57.83 | 5.943 | 0.4328 | 143927.0 | 117000000 | 112000000000 | 121000000000000 | 0.4463 | 0.1845 | 0.0546 | 0.0038 | 0.1914 | 0.0093 | 0.2906 | 0.1053 | 0.1701 | 0.1693 | 0.1184 | 0.2109 | 0.1042 | 0.1922 | 0.0475 | 0.1153 | 0.0156 | 0.0952 | 0.0078 | 0.0987 | 0.0001 | 0.0005 | 0.0011 | 0.0005 | 0.0034 | 0.0014 | 0.0108 | 0.0082 | 0.0532 | 0.0501 | 0.0872 | 0.0742 | 0.0606 | 0.0519 | 0.0872 | 0.0802 | 0.6963 | 0.7330 | 0.0005 | 0.0004 | 0.0021 | 0.0008 | 0.0042 | 0.0052 | 0.0150 | 0.0185 | 0.0656 | 0.0707 | 0.1028 | 0.1137 | 0.0807 | 0.0882 | 0.1081 | 0.1140 | 0.6208 | 0.5885 | 0.0002 | 0.0016 | 0.0046 | 0.0142 | 0.0602 | 0.0943 | 0.0678 | 0.0986 | 0.6586 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 150 | 710 | | 6177 | 14509 | 257.7 | 49.98 | 159.94 | 175.38 | 195 | 216 | 230 | 243 | 255 | 267 | 280 | 296 | 323 | 0.0733 | 1064 | 0.993 | 123.79 | 34.53 | 1 | 0.0478 | 295 | 0.0009 | 53.18 | 7.248 | 0.1699 | 68920.1 | 19100000 | 5500000000 | 1640000000000 | 0.4318 | 0.2171 | 0.0000 | 0.0000 | 0.0009 | 0.0002 | 0.0030 | 0.0002 | 0.0173 | 0.0017 | 0.0536 | 0.0129 | 0.0983 | 0.0305 | 0.1154 | 0.0290 | 0.1599 | 0.0498 | 0.5517 | 0.8757 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0013 | 0.0000 | 0.0044 | 0.0013 | 0.0238 | 0.0098 | 0.0441 | 0.0207 | 0.0492 | 0.0117 | 0.0819 | 0.0218 | 0.7949 | 0.9346 | 0.0103 | 0.0328 | 0.0091 | 0.0437 | 0.0343 | 0.1202 | 0.0926 | 0.1421 | 0.1669 | 0.1585 | 0.1829 | 0.1530 | 0.1291 | 0.0710 | 0.1451 | 0.1202 | 0.2297 | 0.1585 | 0.0007 | 0.0031 | 0.0099 | 0.0358 | 0.0782 | 0.1328 | 0.1171 | 0.1540 | 0.4684 | 16 | 20 | 33 | 57 | 93 | 139 | 201 | 286 | 409 | 0.0208 | 27.02 | 5.804 | 0.4346 | 56339.0 | 28300000 | 18000000000 | 13700000000000 | 0.5203 | 0.1387 | 0.0476 | 0.0018 | 0.1694 | 0.0111 | 0.2272 | 0.1026 | 0.1326 | 0.1244 | 0.1282 | 0.1647 | 0.1104 | 0.1591 | 0.0736 | 0.1121 | 0.0615 | 0.1069 | 0.0495 | 0.2172 | 0.0002 | 0.0000 | 0.0018 | 0.0007 | 0.0049 | 0.0018 | 0.0131 | 0.0102 | 0.0685 | 0.0529 | 0.1030 | 0.0883 | 0.0768 | 0.0614 | 0.1123 | 0.0986 | 0.6194 | 0.6860 | 0.0007 | 0.0003 | 0.0022 | 0.0038 | 0.0046 | 0.0082 | 0.0208 | 0.0260 | 0.0828 | 0.0984 | 0.1265 | 0.1386 | 0.0956 | 0.0989 | 0.1283 | 0.1435 | 0.5386 | 0.4824 | 0.0004 | 0.0027 | 0.0042 | 0.0175 | 0.0747 | 0.1189 | 0.0808 | 0.1256 | 0.5753 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 |