High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1250 | 480 | | 6010 | 16284 | 271.9 | 68.74 | 353.07 | 523.57 | 175 | 224 | 245 | 264 | 279 | 293 | 309 | 328 | 354 | 0.0591 | 962 | 1.159 | 131.22 | 44.78 | 2 | 0.0542 | 326 | 0.0013 | 30.49 | 7.001 | 0.2258 | 78643.6 | 23800000 | 7440000000 | 2400000000000 | 0.4018 | 0.2328 | 0.0008 | 0.0000 | 0.0022 | 0.0004 | 0.0030 | 0.0013 | 0.0170 | 0.0019 | 0.0460 | 0.0171 | 0.0930 | 0.0344 | 0.1038 | 0.0340 | 0.1408 | 0.0511 | 0.5934 | 0.8598 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0002 | 0.0005 | 0.0026 | 0.0011 | 0.0142 | 0.0116 | 0.0318 | 0.0207 | 0.0259 | 0.0136 | 0.0451 | 0.0223 | 0.8798 | 0.9300 | 0.0040 | 0.0119 | 0.0161 | 0.0357 | 0.0185 | 0.0238 | 0.0611 | 0.1111 | 0.0957 | 0.1905 | 0.1262 | 0.1905 | 0.1294 | 0.1349 | 0.1455 | 0.1706 | 0.4035 | 0.1310 | 0.0006 | 0.0009 | 0.0061 | 0.0148 | 0.0439 | 0.0742 | 0.0805 | 0.1147 | 0.6642 | 9 | 12 | 15 | 20 | 33 | 124 | 394 | 769 | 1226 | 0.0716 | 108.75 | 5.493 | 0.4880 | 398768.0 | 556000000 | 859000000000 | 1.42E+15 | 0.4180 | 0.2363 | 0.0593 | 0.0007 | 0.2062 | 0.0235 | 0.3032 | 0.1478 | 0.1442 | 0.1457 | 0.1078 | 0.1974 | 0.0876 | 0.1807 | 0.0499 | 0.1175 | 0.0337 | 0.0960 | 0.0081 | 0.0907 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0016 | 0.0009 | 0.0066 | 0.0043 | 0.0421 | 0.0372 | 0.0706 | 0.0656 | 0.0492 | 0.0439 | 0.0706 | 0.0630 | 0.7590 | 0.7848 | 0.0002 | 0.0002 | 0.0019 | 0.0018 | 0.0028 | 0.0030 | 0.0118 | 0.0149 | 0.0476 | 0.0557 | 0.0800 | 0.0896 | 0.0607 | 0.0667 | 0.0891 | 0.0875 | 0.7059 | 0.6807 | 0.0004 | 0.0010 | 0.0028 | 0.0079 | 0.0436 | 0.0772 | 0.0515 | 0.0798 | 0.7360 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 396 | 817 | | 4083 | 6204 | 171.9 | 49.75 | 200.16 | 197.44 | 116 | 132 | 144 | 155 | 165 | 176 | 190 | 208 | 235 | 0.1065 | 661 | 1.221 | 103.16 | 41.87 | 1 | 0.0649 | 265 | 0.0012 | 45.98 | 6.996 | 0.1927 | 32023.5 | 6460000 | 1410000000 | 334000000000 | 0.4304 | 0.2154 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0147 | 0.0000 | 0.0334 | 0.0020 | 0.1068 | 0.0322 | 0.2065 | 0.0772 | 0.1709 | 0.0735 | 0.1794 | 0.0958 | 0.2875 | 0.7193 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0068 | 0.0013 | 0.0444 | 0.0205 | 0.0995 | 0.0407 | 0.0762 | 0.0329 | 0.1105 | 0.0477 | 0.6614 | 0.8570 | 0.0036 | 0.0000 | 0.0072 | 0.0256 | 0.0191 | 0.0484 | 0.0656 | 0.0769 | 0.1514 | 0.1852 | 0.1907 | 0.2080 | 0.1085 | 0.1026 | 0.1347 | 0.1453 | 0.3194 | 0.2080 | 0.0006 | 0.0055 | 0.0094 | 0.0303 | 0.1069 | 0.1416 | 0.1085 | 0.1344 | 0.4628 | 19 | 36 | 62 | 91 | 131 | 181 | 248 | 345 | 503 | 0.0039 | 114.79 | 6.970 | 0.2743 | 79040.1 | 42000000 | 26100000000 | 18000000000000 | 0.5116 | 0.1429 | 0.0379 | 0.0018 | 0.1569 | 0.0147 | 0.2288 | 0.0728 | 0.2157 | 0.1053 | 0.1542 | 0.1818 | 0.1085 | 0.2240 | 0.0549 | 0.1567 | 0.0275 | 0.1206 | 0.0157 | 0.1224 | 0.0011 | 0.0003 | 0.0022 | 0.0025 | 0.0037 | 0.0040 | 0.0145 | 0.0126 | 0.0764 | 0.0596 | 0.1135 | 0.1007 | 0.0827 | 0.0795 | 0.1228 | 0.1057 | 0.5829 | 0.6351 | 0.0010 | 0.0006 | 0.0031 | 0.0006 | 0.0078 | 0.0049 | 0.0259 | 0.0401 | 0.0953 | 0.1048 | 0.1472 | 0.1572 | 0.0969 | 0.1030 | 0.1358 | 0.1393 | 0.4870 | 0.4494 | 0.0004 | 0.0035 | 0.0031 | 0.0189 | 0.0817 | 0.1339 | 0.0935 | 0.1299 | 0.5351 | ||
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 532 | 476 | | 5219 | 14862 | 435.3 | 124.40 | 337.57 | 481.74 | 232 | 330 | 406 | 440 | 463 | 485 | 504 | 529 | 568 | 0.0615 | 914 | 1.000 | 128.22 | 48.33 | 2 | 0.0674 | 352 | 0.0008 | 45.97 | 7.490 | 0.1610 | 204925.0 | 101000000 | 51900000000 | 27400000000000 | 0.3800 | 0.2460 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0028 | 0.0002 | 0.0186 | 0.0019 | 0.0502 | 0.0190 | 0.0908 | 0.0389 | 0.0881 | 0.0283 | 0.1132 | 0.0482 | 0.6350 | 0.8635 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0009 | 0.0137 | 0.0123 | 0.0238 | 0.0237 | 0.0137 | 0.0121 | 0.0218 | 0.0185 | 0.9249 | 0.9326 | 0.0043 | 0.0084 | 0.0077 | 0.0422 | 0.0163 | 0.0253 | 0.0463 | 0.0633 | 0.0891 | 0.1266 | 0.1380 | 0.2194 | 0.1157 | 0.1181 | 0.1302 | 0.1646 | 0.4524 | 0.2321 | 0.0000 | 0.0000 | 0.0015 | 0.0080 | 0.0250 | 0.0367 | 0.0598 | 0.0712 | 0.7979 | 11 | 14 | 20 | 38 | 87 | 185 | 377 | 650 | 1059 | 0.0509 | 117.91 | 5.882 | 0.4621 | 346014.0 | 476000000 | 763000000000 | 1.34E+15 | 0.4474 | 0.1983 | 0.0233 | 0.0011 | 0.1329 | 0.0091 | 0.3034 | 0.0582 | 0.1982 | 0.0988 | 0.1639 | 0.2045 | 0.0941 | 0.2654 | 0.0532 | 0.1442 | 0.0199 | 0.1116 | 0.0111 | 0.1073 | 0.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0017 | 0.0007 | 0.0048 | 0.0049 | 0.0457 | 0.0381 | 0.0817 | 0.0764 | 0.0489 | 0.0433 | 0.0740 | 0.0659 | 0.7430 | 0.7695 | 0.0002 | 0.0003 | 0.0007 | 0.0008 | 0.0019 | 0.0033 | 0.0107 | 0.0121 | 0.0534 | 0.0598 | 0.0963 | 0.1052 | 0.0590 | 0.0678 | 0.0919 | 0.0965 | 0.6858 | 0.6543 | 0.0000 | 0.0008 | 0.0017 | 0.0079 | 0.0480 | 0.0926 | 0.0499 | 0.0801 | 0.7189 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 320 | 667 | | 5012 | 4003 | 144.6 | 31.00 | 256.96 | 210.61 | 110 | 119 | 126 | 133 | 139 | 146 | 155 | 168 | 187 | 0.1699 | 680 | 1.061 | 130.67 | 36.72 | 1 | 0.0599 | 300 | 0.0023 | 22.41 | 6.404 | 0.2450 | 21873.6 | 3470000 | 577000000 | 101000000000 | 0.4357 | 0.2084 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0059 | 0.0000 | 0.0223 | 0.0013 | 0.0711 | 0.0189 | 0.1355 | 0.0456 | 0.1443 | 0.0439 | 0.1875 | 0.0634 | 0.4320 | 0.8269 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0083 | 0.0004 | 0.0355 | 0.0130 | 0.0649 | 0.0252 | 0.0675 | 0.0144 | 0.0966 | 0.0244 | 0.7237 | 0.9225 | 0.0073 | 0.0036 | 0.0158 | 0.0144 | 0.0280 | 0.0758 | 0.0767 | 0.1516 | 0.1571 | 0.1913 | 0.1705 | 0.1733 | 0.1255 | 0.1264 | 0.1437 | 0.1155 | 0.2753 | 0.1480 | 0.0038 | 0.0080 | 0.0127 | 0.0363 | 0.0930 | 0.1303 | 0.1085 | 0.1567 | 0.4507 | 33 | 63 | 100 | 155 | 208 | 265 | 333 | 424 | 568 | 0.0020 | 118.54 | 7.148 | 0.2176 | 110371.0 | 60900000 | 39200000000 | 28100000000000 | 0.4840 | 0.1833 | 0.0323 | 0.0038 | 0.1232 | 0.0212 | 0.2097 | 0.0613 | 0.2097 | 0.1272 | 0.1730 | 0.1779 | 0.1510 | 0.2059 | 0.0587 | 0.1476 | 0.0293 | 0.1272 | 0.0132 | 0.1279 | 0.0005 | 0.0000 | 0.0055 | 0.0033 | 0.0099 | 0.0087 | 0.0307 | 0.0229 | 0.0823 | 0.0715 | 0.1368 | 0.1227 | 0.1011 | 0.0932 | 0.1293 | 0.1165 | 0.5040 | 0.5611 | 0.0007 | 0.0055 | 0.0045 | 0.0028 | 0.0112 | 0.0148 | 0.0389 | 0.0572 | 0.1243 | 0.1210 | 0.1534 | 0.1681 | 0.1213 | 0.1385 | 0.1445 | 0.1376 | 0.4012 | 0.3546 | 0.0030 | 0.0066 | 0.0156 | 0.0361 | 0.0968 | 0.1437 | 0.1203 | 0.1371 | 0.4408 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 880 | 885 | | 10209 | 13674 | 210.6 | 64.74 | 239.98 | 269.86 | 139 | 157 | 172 | 186 | 201 | 218 | 235 | 258 | 290 | 0.0808 | 1105 | 1.151 | 67.48 | 26.42 | 6 | 0.0172 | 176 | 0.0007 | 71.44 | 7.552 | 0.1615 | 48539.4 | 12300000 | 3450000000 | 1070000000000 | 0.4221 | 0.2180 | 0.0004 | 0.0000 | 0.0033 | 0.0003 | 0.0115 | 0.0010 | 0.0376 | 0.0028 | 0.1041 | 0.0279 | 0.1913 | 0.0622 | 0.1747 | 0.0675 | 0.1796 | 0.0979 | 0.2975 | 0.7403 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0033 | 0.0005 | 0.0121 | 0.0017 | 0.0372 | 0.0177 | 0.0738 | 0.0313 | 0.0693 | 0.0305 | 0.0883 | 0.0432 | 0.7146 | 0.8751 | 0.0023 | 0.0091 | 0.0059 | 0.0136 | 0.0135 | 0.0385 | 0.0594 | 0.1145 | 0.1256 | 0.1531 | 0.1953 | 0.1803 | 0.1085 | 0.0918 | 0.1472 | 0.1168 | 0.3425 | 0.2823 | 0.0007 | 0.0027 | 0.0067 | 0.0258 | 0.0734 | 0.1232 | 0.1052 | 0.1252 | 0.5371 | 16 | 23 | 40 | 77 | 135 | 211 | 305 | 429 | 627 | 0.0143 | 119.92 | 6.776 | 0.3161 | 130409.0 | 96900000 | 85800000000 | 85400000000000 | 0.5316 | 0.1438 | 0.0357 | 0.0030 | 0.1564 | 0.0135 | 0.2778 | 0.0912 | 0.1687 | 0.1243 | 0.1317 | 0.1676 | 0.1036 | 0.1912 | 0.0617 | 0.1297 | 0.0418 | 0.1132 | 0.0226 | 0.1662 | 0.0003 | 0.0004 | 0.0016 | 0.0009 | 0.0038 | 0.0034 | 0.0135 | 0.0085 | 0.0587 | 0.0479 | 0.1129 | 0.0936 | 0.0741 | 0.0654 | 0.1097 | 0.0915 | 0.6255 | 0.6882 | 0.0009 | 0.0013 | 0.0032 | 0.0051 | 0.0090 | 0.0105 | 0.0254 | 0.0239 | 0.0757 | 0.0826 | 0.1232 | 0.1313 | 0.0868 | 0.0987 | 0.1179 | 0.1229 | 0.5578 | 0.5235 | 0.0000 | 0.0022 | 0.0066 | 0.0179 | 0.0664 | 0.1252 | 0.0814 | 0.1093 | 0.5910 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1167 | 689 | | 6111 | 11010 | 86.5 | 25.63 | 194.11 | 227.36 | 55 | 64 | 71 | 78 | 84 | 91 | 98 | 107 | 121 | 0.0750 | 826 | 0.733 | 215.47 | 54.20 | 4 | 0.0928 | 567 | 0.0034 | 11.76 | 5.994 | 0.3193 | 8137.3 | 828575 | 90900000 | 10700000000 | 0.4313 | 0.2183 | 0.0010 | 0.0004 | 0.0045 | 0.0006 | 0.0156 | 0.0018 | 0.0448 | 0.0075 | 0.1171 | 0.0342 | 0.1801 | 0.0744 | 0.1674 | 0.0795 | 0.1944 | 0.1213 | 0.2751 | 0.6804 | 0.0004 | 0.0004 | 0.0011 | 0.0000 | 0.0033 | 0.0004 | 0.0100 | 0.0028 | 0.0462 | 0.0179 | 0.0736 | 0.0369 | 0.0694 | 0.0341 | 0.1040 | 0.0529 | 0.6918 | 0.8547 | 0.0057 | 0.0065 | 0.0086 | 0.0161 | 0.0179 | 0.0581 | 0.0622 | 0.1113 | 0.1237 | 0.1597 | 0.1587 | 0.1968 | 0.1244 | 0.1323 | 0.1494 | 0.1419 | 0.3495 | 0.1774 | 0.0020 | 0.0037 | 0.0116 | 0.0317 | 0.0810 | 0.1161 | 0.1045 | 0.1324 | 0.5170 | 14 | 18 | 27 | 51 | 94 | 159 | 248 | 359 | 533 | 0.0198 | 121.90 | 6.448 | 0.3047 | 89366.6 | 55800000 | 41100000000 | 34000000000000 | 0.4757 | 0.1749 | 0.0822 | 0.0030 | 0.2716 | 0.0287 | 0.3153 | 0.2000 | 0.1093 | 0.1713 | 0.1103 | 0.1866 | 0.0562 | 0.1683 | 0.0416 | 0.0896 | 0.0083 | 0.0733 | 0.0052 | 0.0792 | 0.0007 | 0.0002 | 0.0002 | 0.0008 | 0.0034 | 0.0016 | 0.0104 | 0.0093 | 0.0707 | 0.0599 | 0.1227 | 0.1136 | 0.0860 | 0.0717 | 0.1146 | 0.1087 | 0.5914 | 0.6343 | 0.0006 | 0.0007 | 0.0014 | 0.0039 | 0.0046 | 0.0079 | 0.0149 | 0.0201 | 0.0879 | 0.0911 | 0.1479 | 0.1601 | 0.0948 | 0.0999 | 0.1390 | 0.1443 | 0.5088 | 0.4721 | 0.0003 | 0.0018 | 0.0059 | 0.0132 | 0.0749 | 0.1391 | 0.0892 | 0.1302 | 0.5455 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1030 | 874 | | 3673 | 4603 | 174.5 | 51.15 | 215.89 | 185.55 | 121 | 134 | 145 | 155 | 165 | 176 | 189 | 208 | 237 | 0.1288 | 593 | 1.114 | 100.81 | 36.62 | 1 | 0.0719 | 264 | 0.0014 | 45.62 | 6.851 | 0.2136 | 33048.1 | 6890000 | 1610000000 | 426000000000 | 0.4339 | 0.2118 | 0.0005 | 0.0000 | 0.0029 | 0.0003 | 0.0103 | 0.0009 | 0.0275 | 0.0024 | 0.1035 | 0.0323 | 0.1844 | 0.0579 | 0.1540 | 0.0695 | 0.1923 | 0.1040 | 0.3247 | 0.7325 | 0.0004 | 0.0000 | 0.0011 | 0.0003 | 0.0054 | 0.0006 | 0.0098 | 0.0011 | 0.0493 | 0.0198 | 0.0761 | 0.0320 | 0.0692 | 0.0315 | 0.1036 | 0.0546 | 0.6853 | 0.8602 | 0.0042 | 0.0032 | 0.0083 | 0.0288 | 0.0208 | 0.0192 | 0.0554 | 0.1058 | 0.1302 | 0.1827 | 0.1911 | 0.1538 | 0.0817 | 0.1250 | 0.1440 | 0.1410 | 0.3643 | 0.2404 | 0.0033 | 0.0026 | 0.0131 | 0.0328 | 0.0858 | 0.1343 | 0.0878 | 0.1304 | 0.5098 | 21 | 49 | 86 | 127 | 170 | 218 | 276 | 353 | 485 | 0.0039 | 128.55 | 7.024 | 0.2296 | 81028.4 | 39900000 | 23100000000 | 14900000000000 | 0.4728 | 0.1730 | 0.0382 | 0.0006 | 0.1401 | 0.0110 | 0.2051 | 0.0760 | 0.1949 | 0.1098 | 0.1809 | 0.1696 | 0.1121 | 0.1982 | 0.0650 | 0.1404 | 0.0420 | 0.1261 | 0.0217 | 0.1683 | 0.0009 | 0.0004 | 0.0026 | 0.0011 | 0.0035 | 0.0044 | 0.0215 | 0.0139 | 0.0953 | 0.0645 | 0.1156 | 0.1004 | 0.0888 | 0.0751 | 0.1301 | 0.1084 | 0.5417 | 0.6319 | 0.0013 | 0.0042 | 0.0080 | 0.0059 | 0.0195 | 0.0210 | 0.0436 | 0.0470 | 0.1113 | 0.1293 | 0.1482 | 0.1839 | 0.1261 | 0.1167 | 0.1368 | 0.1310 | 0.4051 | 0.3610 | 0.0021 | 0.0016 | 0.0102 | 0.0376 | 0.0950 | 0.1432 | 0.1073 | 0.1266 | 0.4764 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 284 | 132 | | 3587 | 822 | 127.8 | 29.04 | 269.41 | 172.52 | 95 | 103 | 110 | 116 | 124 | 131 | 139 | 150 | 166 | 0.4538 | 373 | 0.730 | 52.80 | 16.97 | 1 | 0.0435 | 156 | 0.0026 | 19.75 | 6.264 | 0.2480 | 17172.9 | 2430000 | 364000000 | 57600000000 | 0.4499 | 0.2003 | 0.0013 | 0.0000 | 0.0039 | 0.0000 | 0.0057 | 0.0006 | 0.0284 | 0.0024 | 0.0900 | 0.0181 | 0.1429 | 0.0404 | 0.1608 | 0.0440 | 0.2172 | 0.0871 | 0.3497 | 0.8073 | 0.0007 | 0.0000 | 0.0031 | 0.0000 | 0.0021 | 0.0000 | 0.0106 | 0.0011 | 0.0398 | 0.0118 | 0.0621 | 0.0230 | 0.0648 | 0.0149 | 0.1204 | 0.0342 | 0.6964 | 0.9150 | 0.0048 | 0.0197 | 0.0207 | 0.0542 | 0.0287 | 0.0690 | 0.0813 | 0.1232 | 0.1643 | 0.1675 | 0.1978 | 0.1773 | 0.1372 | 0.1330 | 0.1547 | 0.1182 | 0.2105 | 0.1379 | 0.0025 | 0.0044 | 0.0176 | 0.0478 | 0.0806 | 0.1233 | 0.1296 | 0.1517 | 0.4424 | 69 | 114 | 153 | 190 | 229 | 286 | 352 | 427 | 520 | 0.0018 | 138.36 | 6.442 | 0.1434 | 102307.0 | 47200000 | 24500000000 | 13800000000000 | 0.3578 | 0.2281 | 0.0612 | 0.0059 | 0.2245 | 0.0413 | 0.3197 | 0.1150 | 0.1905 | 0.1475 | 0.1020 | 0.2448 | 0.0748 | 0.2035 | 0.0136 | 0.1091 | 0.0136 | 0.0973 | 0.0000 | 0.0354 | 0.0023 | 0.0018 | 0.0093 | 0.0161 | 0.0395 | 0.0233 | 0.0302 | 0.0376 | 0.1674 | 0.1485 | 0.2256 | 0.2093 | 0.1605 | 0.1503 | 0.1581 | 0.1807 | 0.2070 | 0.2326 | 0.0000 | 0.0045 | 0.0071 | 0.0227 | 0.0247 | 0.0455 | 0.0813 | 0.0818 | 0.2226 | 0.2682 | 0.2438 | 0.2182 | 0.1696 | 0.1591 | 0.1060 | 0.0682 | 0.1449 | 0.1318 | 0.0029 | 0.0086 | 0.0173 | 0.0490 | 0.1844 | 0.2478 | 0.1729 | 0.1499 | 0.1671 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1249 | 243 | | 482 | 1741 | 112.1 | 48.48 | 496.07 | 386.37 | 42 | 60 | 88 | 106 | 116 | 127 | 137 | 153 | 174 | 0.1499 | 261 | 1.058 | 86.21 | 27.78 | 3 | 0.4502 | 217 | 0.0029 | 40.32 | 5.929 | 0.1866 | 14918.8 | 2200000 | 349000000 | 58500000000 | 0.3329 | 0.2700 | 0.0000 | 0.0000 | 0.0174 | 0.0000 | 0.0407 | 0.0035 | 0.2035 | 0.0213 | 0.1512 | 0.0922 | 0.1453 | 0.1844 | 0.0988 | 0.0851 | 0.1337 | 0.1418 | 0.2093 | 0.4716 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0027 | 0.0453 | 0.0461 | 0.0937 | 0.0867 | 0.0423 | 0.0298 | 0.0816 | 0.0569 | 0.7311 | 0.7778 | 0.0000 | 0.0115 | 0.0063 | 0.0000 | 0.0252 | 0.0115 | 0.0566 | 0.0575 | 0.1195 | 0.1379 | 0.1258 | 0.1954 | 0.1447 | 0.0920 | 0.1132 | 0.2069 | 0.4088 | 0.2874 | 0.0000 | 0.0000 | 0.0000 | 0.0150 | 0.0789 | 0.1353 | 0.0714 | 0.1504 | 0.5489 | 91 | 159 | 229 | 321 | 421 | 515 | 623 | 761 | 1010 | 0.0012 | 148.81 | 7.039 | 0.1568 | 395283.0 | 416000000 | 525000000000 | 746000000000000 | 0.4447 | 0.2259 | 0.0146 | 0.0059 | 0.0700 | 0.0089 | 0.2012 | 0.0178 | 0.2128 | 0.0624 | 0.1399 | 0.1516 | 0.1808 | 0.2184 | 0.0845 | 0.1798 | 0.0379 | 0.1590 | 0.0583 | 0.1961 | 0.0000 | 0.0018 | 0.0022 | 0.0037 | 0.0132 | 0.0055 | 0.0209 | 0.0193 | 0.0801 | 0.0644 | 0.1207 | 0.1030 | 0.0955 | 0.0828 | 0.1273 | 0.1122 | 0.5401 | 0.6072 | 0.0000 | 0.0048 | 0.0035 | 0.0121 | 0.0141 | 0.0266 | 0.0493 | 0.0725 | 0.1303 | 0.1401 | 0.1708 | 0.1715 | 0.1338 | 0.1232 | 0.1549 | 0.1014 | 0.3433 | 0.3478 | 0.0014 | 0.0014 | 0.0149 | 0.0408 | 0.0883 | 0.1386 | 0.1264 | 0.1522 | 0.4361 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 321 | 840 | | 426 | 368 | 95.5 | 47.70 | 697.86 | 488.70 | 32 | 42 | 60 | 77 | 96 | 112 | 127 | 143 | 162 | 0.4701 | 173 | 0.664 | 93.61 | 19.80 | 1 | 0.5915 | 252 | 0.0030 | 67.57 | 5.878 | 0.1356 | 11384.7 | 1540000 | 222000000 | 33700000000 | 0.2891 | 0.3236 | 0.0000 | 0.0000 | 0.0000 | 0.0052 | 0.1616 | 0.0000 | 0.1919 | 0.0155 | 0.2121 | 0.1503 | 0.1515 | 0.2591 | 0.2020 | 0.1295 | 0.0404 | 0.1969 | 0.0404 | 0.2435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0032 | 0.0575 | 0.0583 | 0.0996 | 0.0841 | 0.0421 | 0.0388 | 0.0613 | 0.0680 | 0.7318 | 0.7476 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0247 | 0.0517 | 0.0802 | 0.0862 | 0.1049 | 0.1897 | 0.0988 | 0.1207 | 0.1420 | 0.1034 | 0.5432 | 0.4483 | 0.0000 | 0.0000 | 0.0000 | 0.0140 | 0.0698 | 0.0930 | 0.0512 | 0.0884 | 0.6837 | 135 | 270 | 399 | 510 | 616 | 717 | 852 | 1036 | 1456 | 0.0038 | 170.10 | 5.726 | 0.1849 | 725176.0 | 955000000 | 1470000000000 | 2.5E+15 | 0.4289 | 0.2015 | 0.0465 | 0.0000 | 0.1860 | 0.0120 | 0.2558 | 0.0663 | 0.1279 | 0.1205 | 0.1047 | 0.2651 | 0.1395 | 0.2108 | 0.0814 | 0.1566 | 0.0581 | 0.0904 | 0.0000 | 0.0783 | 0.0050 | 0.0000 | 0.0300 | 0.0000 | 0.0550 | 0.0405 | 0.0750 | 0.0526 | 0.1250 | 0.1579 | 0.1600 | 0.1741 | 0.1700 | 0.1660 | 0.1450 | 0.1296 | 0.2350 | 0.2794 | 0.0439 | 0.0000 | 0.0351 | 0.0000 | 0.0263 | 0.0864 | 0.1228 | 0.0864 | 0.1053 | 0.1605 | 0.2193 | 0.1235 | 0.0965 | 0.1111 | 0.0965 | 0.1358 | 0.2544 | 0.2963 | 0.0132 | 0.0395 | 0.0724 | 0.0921 | 0.1645 | 0.1579 | 0.1382 | 0.0921 | 0.2303 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |