High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 644 | 300 | 381 | 806 | 12.1 | 3.51 | 5.40 | 1.98 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 17 | 0.3623 | 292 | 0.804 | 32.02 | 8.25 | 0 | 0.2283 | 87 | 0.0100 | 11.54 | 4.797 | 0.2819 | 158.7 | 2234.75 | 33514.1 | 530731 | 0.4187 | 0.2080 | 0.0000 | 0.0000 | 0.0459 | 0.0000 | 0.1429 | 0.0033 | 0.1837 | 0.0262 | 0.2143 | 0.1082 | 0.2245 | 0.1934 | 0.1071 | 0.1836 | 0.0663 | 0.2787 | 0.0153 | 0.2066 | 0.0000 | 0.0000 | 0.0179 | 0.0000 | 0.0286 | 0.0000 | 0.0536 | 0.0143 | 0.0929 | 0.0602 | 0.1071 | 0.0659 | 0.1464 | 0.1347 | 0.1929 | 0.2063 | 0.3607 | 0.5186 | 0.0238 | 0.0682 | 0.1310 | 0.2045 | 0.1310 | 0.1136 | 0.2262 | 0.1591 | 0.1667 | 0.1364 | 0.1548 | 0.2273 | 0.0595 | 0.0455 | 0.0833 | 0.0455 | 0.0238 | 0.0000 | 0.0094 | 0.0330 | 0.0377 | 0.0566 | 0.1226 | 0.1509 | 0.1462 | 0.2217 | 0.2217 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0262 | 8.53 | 4.026 | 0.3635 | 33.1 | 222.937 | 1630.58 | 12844 | 0.5218 | 0.1301 | 0.0340 | 0.0037 | 0.1671 | 0.0201 | 0.2125 | 0.0713 | 0.2351 | 0.1755 | 0.2153 | 0.2194 | 0.0963 | 0.2102 | 0.0397 | 0.1481 | 0.0000 | 0.1097 | 0.0000 | 0.0420 | 0.0014 | 0.0013 | 0.0029 | 0.0000 | 0.0203 | 0.0053 | 0.0695 | 0.0420 | 0.1462 | 0.1183 | 0.1650 | 0.1367 | 0.1838 | 0.1380 | 0.2489 | 0.2076 | 0.1621 | 0.3509 | 0.0355 | 0.1308 | 0.1450 | 0.2664 | 0.2367 | 0.2617 | 0.2426 | 0.1215 | 0.1538 | 0.1308 | 0.0947 | 0.0607 | 0.0562 | 0.0187 | 0.0266 | 0.0000 | 0.0089 | 0.0093 | 0.0018 | 0.0235 | 0.0868 | 0.1374 | 0.1953 | 0.2441 | 0.2080 | 0.0759 | 0.0271 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1156 | 346 | 318 | 920 | 14.3 | 4.68 | 5.30 | 2.36 | 9 | 10 | 12 | 13 | 14 | 14 | 16 | 17 | 21 | 0.2957 | 272 | 1.375 | 23.54 | 9.49 | 0 | 0.1855 | 59 | 0.0096 | 15.54 | 4.861 | 0.2753 | 224.9 | 3921.78 | 75133.4 | 1570000 | 0.3709 | 0.2571 | 0.0068 | 0.0000 | 0.0608 | 0.0000 | 0.0541 | 0.0000 | 0.1689 | 0.0498 | 0.2365 | 0.0805 | 0.1419 | 0.0958 | 0.1824 | 0.1149 | 0.1149 | 0.2835 | 0.0338 | 0.3755 | 0.0000 | 0.0000 | 0.0177 | 0.0000 | 0.0044 | 0.0000 | 0.0354 | 0.0301 | 0.1150 | 0.0569 | 0.0885 | 0.0535 | 0.1726 | 0.0635 | 0.1770 | 0.1639 | 0.3894 | 0.6321 | 0.0128 | 0.0789 | 0.0513 | 0.0526 | 0.0641 | 0.0263 | 0.0641 | 0.0526 | 0.1154 | 0.1842 | 0.1667 | 0.0789 | 0.1667 | 0.1579 | 0.1795 | 0.1842 | 0.1795 | 0.1842 | 0.0000 | 0.0248 | 0.0745 | 0.1056 | 0.1242 | 0.1242 | 0.1553 | 0.1553 | 0.2360 | 3 | 3 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0283 | 11.90 | 3.904 | 0.3091 | 33.7 | 240.012 | 1881.41 | 15989.2 | 0.5312 | 0.1181 | 0.1609 | 0.0033 | 0.2913 | 0.0384 | 0.3000 | 0.0801 | 0.1913 | 0.1436 | 0.0522 | 0.2053 | 0.0043 | 0.2354 | 0.0000 | 0.1803 | 0.0000 | 0.0835 | 0.0000 | 0.0301 | 0.0000 | 0.0000 | 0.0124 | 0.0000 | 0.0495 | 0.0132 | 0.1533 | 0.0444 | 0.2059 | 0.1187 | 0.2384 | 0.1007 | 0.2043 | 0.1775 | 0.1130 | 0.2818 | 0.0232 | 0.2638 | 0.0240 | 0.1277 | 0.0962 | 0.2681 | 0.2308 | 0.2766 | 0.2837 | 0.2383 | 0.2139 | 0.0766 | 0.1106 | 0.0128 | 0.0313 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0496 | 0.1597 | 0.2031 | 0.2357 | 0.2031 | 0.1132 | 0.0233 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 395 | 909 | 589 | 5786 | 12.0 | 2.37 | 6.24 | 2.23 | 9 | 10 | 11 | 11 | 12 | 12 | 13 | 14 | 15 | 0.0990 | 573 | 0.731 | 73.43 | 17.00 | 0 | 0.3192 | 188 | 0.0185 | 6.32 | 4.289 | 0.3960 | 150.6 | 1953.66 | 26252.6 | 364792 | 0.3695 | 0.2656 | 0.0046 | 0.0000 | 0.0069 | 0.0018 | 0.0324 | 0.0036 | 0.0694 | 0.0164 | 0.1019 | 0.0455 | 0.1343 | 0.0764 | 0.1898 | 0.1218 | 0.1736 | 0.1818 | 0.2870 | 0.5527 | 0.0000 | 0.0000 | 0.0077 | 0.0000 | 0.0174 | 0.0017 | 0.0367 | 0.0156 | 0.0405 | 0.0363 | 0.0656 | 0.0554 | 0.1158 | 0.0606 | 0.1409 | 0.1125 | 0.5753 | 0.7180 | 0.0581 | 0.2857 | 0.0930 | 0.2500 | 0.1860 | 0.1071 | 0.1163 | 0.1786 | 0.1744 | 0.1071 | 0.1163 | 0.0714 | 0.0814 | 0.0000 | 0.1163 | 0.0000 | 0.0581 | 0.0000 | 0.0153 | 0.0337 | 0.0706 | 0.0982 | 0.1135 | 0.1350 | 0.1380 | 0.1503 | 0.2454 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0198 | 11.10 | 4.314 | 0.3248 | 43.9 | 336.777 | 2778.03 | 24382.5 | 0.5530 | 0.1191 | 0.0068 | 0.0000 | 0.0407 | 0.0041 | 0.1143 | 0.0182 | 0.2166 | 0.0597 | 0.2673 | 0.1261 | 0.2088 | 0.2311 | 0.1023 | 0.2725 | 0.0370 | 0.2133 | 0.0062 | 0.0750 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0121 | 0.0032 | 0.0364 | 0.0132 | 0.0907 | 0.0355 | 0.1684 | 0.0778 | 0.2678 | 0.1906 | 0.2778 | 0.3647 | 0.1454 | 0.3144 | 0.1144 | 0.2816 | 0.2397 | 0.3609 | 0.2950 | 0.2346 | 0.1896 | 0.0927 | 0.1073 | 0.0268 | 0.0392 | 0.0034 | 0.0141 | 0.0000 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0090 | 0.0356 | 0.0844 | 0.1569 | 0.2511 | 0.2490 | 0.1644 | 0.0477 | |
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1199 | 269 | 6858 | 34380 | 182.5 | 52.85 | 124.86 | 199.10 | 122 | 141 | 154 | 165 | 177 | 190 | 204 | 222 | 256 | 0.0332 | 1142 | 0.787 | 31.00 | 8.06 | 3 | 0.0117 | 80 | 0.0011 | 37.84 | 7.176 | 0.1947 | 36107.4 | 7670000 | 1740000000 | 418000000000 | 0.4164 | 0.2188 | 0.0008 | 0.0000 | 0.0016 | 0.0003 | 0.0074 | 0.0003 | 0.0251 | 0.0031 | 0.0740 | 0.0238 | 0.1294 | 0.0417 | 0.1524 | 0.0466 | 0.1762 | 0.0732 | 0.4332 | 0.8108 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0012 | 0.0321 | 0.0128 | 0.0530 | 0.0208 | 0.0614 | 0.0187 | 0.0821 | 0.0317 | 0.7569 | 0.9147 | 0.0035 | 0.0089 | 0.0090 | 0.0089 | 0.0097 | 0.0222 | 0.0520 | 0.0532 | 0.0929 | 0.1064 | 0.1283 | 0.1241 | 0.0999 | 0.1004 | 0.1200 | 0.1241 | 0.4847 | 0.4520 | 0.0016 | 0.0038 | 0.0074 | 0.0272 | 0.0579 | 0.0886 | 0.0908 | 0.1164 | 0.6063 | 17 | 21 | 25 | 29 | 35 | 48 | 91 | 194 | 364 | 0.0577 | 29.38 | 4.737 | 0.5383 | 55230.0 | 41200000 | 40500000000 | 47700000000000 | 0.3925 | 0.2378 | 0.1380 | 0.0050 | 0.3601 | 0.0465 | 0.2981 | 0.2724 | 0.1080 | 0.2297 | 0.0587 | 0.1914 | 0.0244 | 0.1219 | 0.0089 | 0.0649 | 0.0028 | 0.0419 | 0.0011 | 0.0263 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0019 | 0.0020 | 0.0186 | 0.0147 | 0.0758 | 0.0670 | 0.1162 | 0.0990 | 0.0798 | 0.0694 | 0.1195 | 0.1071 | 0.5878 | 0.6402 | 0.0002 | 0.0003 | 0.0007 | 0.0022 | 0.0033 | 0.0056 | 0.0256 | 0.0302 | 0.0905 | 0.0964 | 0.1439 | 0.1483 | 0.0934 | 0.1014 | 0.1314 | 0.1378 | 0.5108 | 0.4778 | 0.0002 | 0.0007 | 0.0022 | 0.0238 | 0.0786 | 0.1331 | 0.0854 | 0.1281 | 0.5480 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 644 | 509 | 752 | 2601 | 109.3 | 22.70 | 27.66 | 36.83 | 79 | 89 | 97 | 104 | 110 | 117 | 123 | 130 | 139 | 0.1303 | 339 | 0.980 | 171.76 | 54.15 | 1 | 0.6197 | 466 | 0.0023 | 47.96 | 6.181 | 0.1607 | 12466.6 | 1470000 | 179000000 | 22400000000 | 0.3827 | 0.2423 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0151 | 0.0000 | 0.0538 | 0.0042 | 0.1075 | 0.0379 | 0.1613 | 0.0618 | 0.1527 | 0.0520 | 0.2022 | 0.0758 | 0.3032 | 0.7683 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0114 | 0.0041 | 0.0507 | 0.0346 | 0.0654 | 0.0553 | 0.0670 | 0.0346 | 0.1029 | 0.0581 | 0.7010 | 0.8133 | 0.0204 | 0.0000 | 0.0272 | 0.0909 | 0.0612 | 0.3636 | 0.0952 | 0.2727 | 0.1837 | 0.0909 | 0.1361 | 0.1818 | 0.1633 | 0.0000 | 0.1769 | 0.0000 | 0.1361 | 0.0000 | 0.0000 | 0.0025 | 0.0101 | 0.0404 | 0.0783 | 0.1364 | 0.1364 | 0.1338 | 0.4621 | 13 | 14 | 15 | 16 | 17 | 18 | 21 | 29 | 50 | 0.5312 | 1.01 | 1.471 | 0.9002 | 2121.0 | 439440 | 138000000 | 49900000000 | 0.6286 | 0.0988 | 0.0545 | 0.0328 | 0.0955 | 0.0864 | 0.2136 | 0.1351 | 0.2136 | 0.1033 | 0.1727 | 0.1360 | 0.1091 | 0.1360 | 0.0909 | 0.1241 | 0.0364 | 0.1311 | 0.0136 | 0.1152 | 0.0104 | 0.0219 | 0.0104 | 0.0629 | 0.0207 | 0.0950 | 0.0370 | 0.0673 | 0.1111 | 0.0994 | 0.1156 | 0.0892 | 0.1319 | 0.1001 | 0.1452 | 0.1235 | 0.4178 | 0.3406 | 0.0000 | 0.0000 | 0.0022 | 0.0249 | 0.0198 | 0.0305 | 0.0440 | 0.0693 | 0.1604 | 0.1662 | 0.1758 | 0.1801 | 0.1297 | 0.1468 | 0.1714 | 0.1634 | 0.2967 | 0.2188 | 0.0036 | 0.0073 | 0.0146 | 0.0419 | 0.1421 | 0.1512 | 0.1275 | 0.1658 | 0.3461 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 688 | 724 | 382 | 3170 | 111.2 | 49.61 | 43.27 | 125.08 | 45 | 55 | 71 | 91 | 111 | 133 | 151 | 163 | 177 | 0.1344 | 426 | 0.422 | 253.34 | 46.17 | 1 | 2.3037 | 880 | 0.0037 | 31.49 | 5.680 | 0.1888 | 14813.4 | 2190000 | 345000000 | 56300000000 | 0.2747 | 0.3491 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.2262 | 0.0345 | 0.3929 | 0.1379 | 0.2857 | 0.2184 | 0.0357 | 0.1494 | 0.0595 | 0.2184 | 0.0000 | 0.2356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0072 | 0.0681 | 0.0578 | 0.0851 | 0.0866 | 0.0511 | 0.0433 | 0.0681 | 0.0650 | 0.7191 | 0.7401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0194 | 0.0927 | 0.1553 | 0.1192 | 0.1165 | 0.0397 | 0.0971 | 0.1060 | 0.1165 | 0.6424 | 0.4854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0733 | 0.1257 | 0.0314 | 0.0733 | 0.6963 | 7 | 8 | 9 | 10 | 10 | 11 | 12 | 15 | 33 | 0.6117 | 5.34 | 1.436 | 0.8850 | 17511.8 | 11000000 | 7740000000 | 5940000000000 | 0.6927 | 0.0495 | 0.0357 | 0.0000 | 0.1429 | 0.0385 | 0.2857 | 0.0641 | 0.2143 | 0.1538 | 0.1786 | 0.2436 | 0.1429 | 0.1923 | 0.0000 | 0.1154 | 0.0000 | 0.1538 | 0.0000 | 0.0385 | 0.0032 | 0.0000 | 0.0064 | 0.0085 | 0.0064 | 0.0141 | 0.0129 | 0.0226 | 0.0386 | 0.0621 | 0.0611 | 0.0424 | 0.0675 | 0.0621 | 0.0868 | 0.1017 | 0.7170 | 0.6864 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0035 | 0.0000 | 0.0106 | 0.0181 | 0.0565 | 0.0471 | 0.0636 | 0.0870 | 0.0777 | 0.0725 | 0.0777 | 0.0725 | 0.7102 | 0.6993 | 0.0000 | 0.0000 | 0.0068 | 0.0102 | 0.0476 | 0.0612 | 0.0714 | 0.0884 | 0.7143 | |||
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1089 | 808 | 9170 | 24605 | 276.9 | 78.28 | 148.86 | 243.52 | 189 | 217 | 236 | 252 | 269 | 287 | 308 | 335 | 379 | 0.0478 | 1177 | 0.975 | 178.47 | 49.01 | 3 | 0.0484 | 444 | 0.0005 | 83.21 | 7.806 | 0.1414 | 82817.9 | 26600000 | 9120000000 | 3340000000000 | 0.3821 | 0.2526 | 0.0006 | 0.0000 | 0.0006 | 0.0003 | 0.0050 | 0.0006 | 0.0193 | 0.0027 | 0.0640 | 0.0215 | 0.1201 | 0.0404 | 0.1246 | 0.0400 | 0.1755 | 0.0620 | 0.4903 | 0.8326 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0081 | 0.0007 | 0.0235 | 0.0104 | 0.0451 | 0.0203 | 0.0512 | 0.0147 | 0.0759 | 0.0249 | 0.7939 | 0.9289 | 0.0042 | 0.0025 | 0.0052 | 0.0076 | 0.0157 | 0.0290 | 0.0408 | 0.0718 | 0.0963 | 0.1272 | 0.1387 | 0.1348 | 0.0994 | 0.1083 | 0.1251 | 0.1486 | 0.4746 | 0.3703 | 0.0014 | 0.0038 | 0.0107 | 0.0227 | 0.0568 | 0.0940 | 0.0838 | 0.1095 | 0.6172 | 10 | 13 | 15 | 19 | 31 | 61 | 125 | 239 | 462 | 0.0836 | 33.10 | 4.848 | 0.5636 | 81459.4 | 66300000 | 65000000000 | 71600000000000 | 0.3987 | 0.2387 | 0.0508 | 0.0023 | 0.1457 | 0.0182 | 0.2453 | 0.0872 | 0.1798 | 0.1196 | 0.1631 | 0.1870 | 0.1009 | 0.1877 | 0.0602 | 0.1413 | 0.0328 | 0.1066 | 0.0214 | 0.1501 | 0.0005 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0019 | 0.0118 | 0.0111 | 0.0408 | 0.0392 | 0.0780 | 0.0652 | 0.0537 | 0.0500 | 0.0809 | 0.0683 | 0.7301 | 0.7639 | 0.0008 | 0.0004 | 0.0010 | 0.0022 | 0.0038 | 0.0053 | 0.0155 | 0.0224 | 0.0573 | 0.0634 | 0.0994 | 0.0936 | 0.0692 | 0.0729 | 0.0878 | 0.0951 | 0.6653 | 0.6447 | 0.0003 | 0.0010 | 0.0025 | 0.0126 | 0.0505 | 0.0841 | 0.0681 | 0.0859 | 0.6949 | |||
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 787 | 786 | 14112 | 32367 | 245.5 | 77.16 | 146.77 | 228.26 | 156 | 185 | 205 | 221 | 237 | 254 | 274 | 301 | 345 | 0.0488 | 1581 | 0.669 | 148.12 | 27.73 | 3 | 0.0257 | 363 | 0.0006 | 60.19 | 7.782 | 0.1687 | 66225.0 | 19500000 | 6230000000 | 2150000000000 | 0.4164 | 0.2099 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0068 | 0.0005 | 0.0211 | 0.0043 | 0.0673 | 0.0249 | 0.1414 | 0.0502 | 0.1309 | 0.0527 | 0.1587 | 0.0666 | 0.4724 | 0.8007 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0003 | 0.0074 | 0.0026 | 0.0218 | 0.0131 | 0.0526 | 0.0251 | 0.0492 | 0.0237 | 0.0741 | 0.0308 | 0.7916 | 0.9043 | 0.0010 | 0.0021 | 0.0033 | 0.0076 | 0.0118 | 0.0125 | 0.0393 | 0.0569 | 0.1035 | 0.1090 | 0.1432 | 0.1444 | 0.0996 | 0.0938 | 0.1288 | 0.1146 | 0.4695 | 0.4590 | 0.0005 | 0.0024 | 0.0074 | 0.0199 | 0.0565 | 0.1073 | 0.0842 | 0.1154 | 0.6063 | 13 | 15 | 17 | 22 | 34 | 66 | 132 | 244 | 448 | 0.0654 | 39.84 | 4.972 | 0.5439 | 73640.4 | 55300000 | 50400000000 | 51700000000000 | 0.5011 | 0.1602 | 0.0623 | 0.0031 | 0.2185 | 0.0242 | 0.2928 | 0.1386 | 0.1538 | 0.1668 | 0.1059 | 0.2014 | 0.0738 | 0.1699 | 0.0455 | 0.1175 | 0.0254 | 0.0808 | 0.0220 | 0.0977 | 0.0000 | 0.0003 | 0.0009 | 0.0002 | 0.0020 | 0.0009 | 0.0125 | 0.0097 | 0.0604 | 0.0529 | 0.0922 | 0.0798 | 0.0683 | 0.0642 | 0.1028 | 0.0895 | 0.6609 | 0.7026 | 0.0001 | 0.0004 | 0.0013 | 0.0019 | 0.0031 | 0.0054 | 0.0184 | 0.0221 | 0.0771 | 0.0786 | 0.1154 | 0.1217 | 0.0827 | 0.0911 | 0.1160 | 0.1245 | 0.5858 | 0.5543 | 0.0004 | 0.0009 | 0.0021 | 0.0159 | 0.0682 | 0.1066 | 0.0762 | 0.1087 | 0.6210 | |||
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 771 | 729 | 699 | 8074 | 51.0 | 15.12 | 134.99 | 188.23 | 31 | 35 | 40 | 45 | 50 | 56 | 62 | 67 | 72 | 0.0588 | 475 | 1.025 | 40.01 | 10.20 | 1 | 0.1373 | 96 | 0.0059 | 6.82 | 5.319 | 0.3605 | 2826.1 | 167621 | 10500000 | 678000000 | 0.3593 | 0.2671 | 0.0074 | 0.0000 | 0.0223 | 0.0106 | 0.0186 | 0.0195 | 0.0483 | 0.0283 | 0.1264 | 0.0496 | 0.1561 | 0.0637 | 0.1822 | 0.0991 | 0.2119 | 0.1558 | 0.2268 | 0.5735 | 0.0000 | 0.0000 | 0.0021 | 0.0016 | 0.0021 | 0.0094 | 0.0125 | 0.0141 | 0.0480 | 0.0297 | 0.0438 | 0.0375 | 0.0438 | 0.0531 | 0.0710 | 0.0688 | 0.7766 | 0.7859 | 0.0000 | 0.0267 | 0.0095 | 0.0533 | 0.0095 | 0.0533 | 0.0714 | 0.1867 | 0.0571 | 0.1333 | 0.0857 | 0.2000 | 0.1333 | 0.1733 | 0.1762 | 0.1467 | 0.4571 | 0.0267 | 0.0000 | 0.0029 | 0.0086 | 0.0201 | 0.0430 | 0.0630 | 0.0516 | 0.0860 | 0.7249 | 17 | 20 | 22 | 27 | 42 | 69 | 121 | 231 | 414 | 0.1036 | 10.05 | 4.238 | 0.6273 | 53649.5 | 30800000 | 20700000000 | 15500000000000 | 0.6068 | 0.0942 | 0.0493 | 0.0037 | 0.1637 | 0.0266 | 0.2249 | 0.1322 | 0.1657 | 0.1506 | 0.1400 | 0.1304 | 0.1183 | 0.1680 | 0.0552 | 0.1074 | 0.0414 | 0.0973 | 0.0414 | 0.1837 | 0.0004 | 0.0007 | 0.0012 | 0.0013 | 0.0046 | 0.0030 | 0.0150 | 0.0167 | 0.0547 | 0.0407 | 0.0875 | 0.0781 | 0.0586 | 0.0524 | 0.0848 | 0.0851 | 0.6933 | 0.7219 | 0.0005 | 0.0005 | 0.0019 | 0.0042 | 0.0043 | 0.0100 | 0.0168 | 0.0173 | 0.0570 | 0.0614 | 0.1049 | 0.0992 | 0.0608 | 0.0719 | 0.0967 | 0.1028 | 0.6571 | 0.6327 | 0.0000 | 0.0039 | 0.0035 | 0.0195 | 0.0500 | 0.0925 | 0.0626 | 0.0947 | 0.6733 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 372 | 139 | 4417 | 11190 | 35.9 | 14.42 | 6.81 | 2.68 | 18 | 23 | 27 | 31 | 35 | 38 | 42 | 47 | 55 | 0.1108 | 1240 | 0.972 | 96.52 | 27.73 | 0 | 0.0541 | 239 | 0.0016 | 19.80 | 6.657 | 0.2399 | 1496.0 | 70708.7 | 3720000 | 215000000 | 0.3566 | 0.2612 | 0.0074 | 0.0033 | 0.0138 | 0.0046 | 0.0275 | 0.0100 | 0.0401 | 0.0219 | 0.0682 | 0.0306 | 0.1181 | 0.0604 | 0.1456 | 0.0764 | 0.2189 | 0.1249 | 0.3605 | 0.6679 | 0.0027 | 0.0016 | 0.0044 | 0.0025 | 0.0061 | 0.0041 | 0.0123 | 0.0106 | 0.0194 | 0.0144 | 0.0310 | 0.0289 | 0.0358 | 0.0324 | 0.0607 | 0.0501 | 0.8275 | 0.8554 | 0.0135 | 0.0136 | 0.0143 | 0.0303 | 0.0236 | 0.0394 | 0.0412 | 0.0455 | 0.0648 | 0.0636 | 0.0732 | 0.0924 | 0.0875 | 0.1030 | 0.1052 | 0.1288 | 0.5766 | 0.4833 | 0.0024 | 0.0118 | 0.0142 | 0.0217 | 0.0307 | 0.0558 | 0.0728 | 0.1281 | 0.6626 | 3 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0130 | 14.88 | 4.690 | 0.2835 | 53.5 | 466.389 | 4418.91 | 44994.1 | 0.5386 | 0.1220 | 0.0193 | 0.0018 | 0.0771 | 0.0147 | 0.1782 | 0.0531 | 0.2352 | 0.1151 | 0.2415 | 0.1932 | 0.1553 | 0.2539 | 0.0676 | 0.2164 | 0.0219 | 0.1202 | 0.0039 | 0.0316 | 0.0009 | 0.0001 | 0.0099 | 0.0021 | 0.0376 | 0.0123 | 0.0944 | 0.0380 | 0.1707 | 0.0873 | 0.2304 | 0.1689 | 0.2167 | 0.2533 | 0.1681 | 0.2793 | 0.0711 | 0.1586 | 0.1499 | 0.2801 | 0.2687 | 0.3198 | 0.2320 | 0.2121 | 0.1617 | 0.1088 | 0.0909 | 0.0480 | 0.0568 | 0.0201 | 0.0279 | 0.0084 | 0.0099 | 0.0022 | 0.0022 | 0.0006 | 0.0072 | 0.0437 | 0.1150 | 0.1799 | 0.2208 | 0.1990 | 0.1331 | 0.0731 | 0.0283 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 501 | 504 | 10483 | 29050 | 333.7 | 87.79 | 177.85 | 262.57 | 236 | 272 | 293 | 313 | 331 | 350 | 372 | 400 | 442 | 0.0518 | 1504 | 0.386 | 149.64 | 20.59 | 5 | 0.0405 | 425 | 0.0005 | 88.21 | 7.897 | 0.1404 | 119081.0 | 44900000 | 17800000000 | 7380000000000 | 0.4581 | 0.1796 | 0.0000 | 0.0000 | 0.0012 | 0.0001 | 0.0040 | 0.0003 | 0.0124 | 0.0024 | 0.0524 | 0.0199 | 0.0976 | 0.0409 | 0.1048 | 0.0282 | 0.1371 | 0.0397 | 0.5905 | 0.8683 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0043 | 0.0009 | 0.0218 | 0.0129 | 0.0408 | 0.0249 | 0.0434 | 0.0140 | 0.0546 | 0.0203 | 0.8331 | 0.9269 | 0.0063 | 0.0043 | 0.0058 | 0.0029 | 0.0184 | 0.0200 | 0.0442 | 0.0428 | 0.0738 | 0.1056 | 0.1169 | 0.1469 | 0.1004 | 0.0984 | 0.1145 | 0.1213 | 0.5197 | 0.4579 | 0.0012 | 0.0029 | 0.0078 | 0.0171 | 0.0536 | 0.0699 | 0.0740 | 0.0962 | 0.6774 | 11 | 14 | 18 | 25 | 50 | 97 | 178 | 304 | 548 | 0.0648 | 33.20 | 5.292 | 0.5122 | 100572.0 | 82800000 | 82800000000 | 94100000000000 | 0.3716 | 0.2666 | 0.0296 | 0.0017 | 0.1361 | 0.0083 | 0.2160 | 0.0670 | 0.1652 | 0.1170 | 0.1568 | 0.1755 | 0.1326 | 0.1840 | 0.0774 | 0.1333 | 0.0483 | 0.1272 | 0.0380 | 0.1861 | 0.0001 | 0.0003 | 0.0009 | 0.0003 | 0.0034 | 0.0025 | 0.0112 | 0.0111 | 0.0428 | 0.0397 | 0.0676 | 0.0625 | 0.0535 | 0.0451 | 0.0718 | 0.0631 | 0.7487 | 0.7755 | 0.0005 | 0.0007 | 0.0015 | 0.0023 | 0.0044 | 0.0056 | 0.0156 | 0.0203 | 0.0529 | 0.0545 | 0.0833 | 0.0881 | 0.0667 | 0.0649 | 0.0827 | 0.0819 | 0.6924 | 0.6817 | 0.0002 | 0.0008 | 0.0029 | 0.0164 | 0.0438 | 0.0782 | 0.0630 | 0.0794 | 0.7154 | |||
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1109 | 467 | 7728 | 10985 | 187.4 | 61.96 | 106.16 | 170.18 | 109 | 128 | 147 | 169 | 186 | 203 | 220 | 239 | 268 | 0.0861 | 946 | 1.180 | 100.90 | 29.02 | 3 | 0.0294 | 227 | 0.0011 | 27.43 | 7.104 | 0.2644 | 38959.5 | 8810000 | 2140000000 | 549000000000 | 0.4404 | 0.1893 | 0.0019 | 0.0005 | 0.0066 | 0.0013 | 0.0109 | 0.0023 | 0.0241 | 0.0084 | 0.0675 | 0.0240 | 0.0947 | 0.0473 | 0.0944 | 0.0455 | 0.1310 | 0.0624 | 0.5688 | 0.8083 | 0.0006 | 0.0003 | 0.0015 | 0.0009 | 0.0032 | 0.0012 | 0.0043 | 0.0039 | 0.0171 | 0.0115 | 0.0221 | 0.0195 | 0.0225 | 0.0169 | 0.0332 | 0.0232 | 0.8955 | 0.9226 | 0.0028 | 0.0045 | 0.0052 | 0.0034 | 0.0131 | 0.0101 | 0.0197 | 0.0515 | 0.0553 | 0.1074 | 0.0933 | 0.1398 | 0.0778 | 0.1040 | 0.1172 | 0.1275 | 0.6157 | 0.4519 | 0.0003 | 0.0005 | 0.0034 | 0.0120 | 0.0330 | 0.0494 | 0.0546 | 0.0738 | 0.7730 | 10 | 13 | 16 | 20 | 29 | 52 | 97 | 156 | 295 | 0.0735 | 19.46 | 4.540 | 0.5815 | 40229.5 | 25000000 | 19500000000 | 17300000000000 | 0.4726 | 0.1847 | 0.0486 | 0.0029 | 0.0972 | 0.0161 | 0.1627 | 0.0732 | 0.1333 | 0.0992 | 0.1345 | 0.1522 | 0.1390 | 0.1690 | 0.0949 | 0.1107 | 0.0836 | 0.1148 | 0.1062 | 0.2618 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0042 | 0.0027 | 0.0152 | 0.0126 | 0.0576 | 0.0567 | 0.0829 | 0.0680 | 0.0576 | 0.0508 | 0.0880 | 0.0841 | 0.6936 | 0.7242 | 0.0007 | 0.0009 | 0.0045 | 0.0047 | 0.0064 | 0.0108 | 0.0288 | 0.0284 | 0.0804 | 0.0814 | 0.0932 | 0.1063 | 0.0718 | 0.0689 | 0.1044 | 0.1029 | 0.6098 | 0.5958 | 0.0003 | 0.0019 | 0.0055 | 0.0183 | 0.0685 | 0.0985 | 0.0711 | 0.1046 | 0.6313 | |||
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 374 | 827 | 538 | 5755 | 91.8 | 48.44 | 171.54 | 297.95 | 29 | 40 | 57 | 74 | 89 | 101 | 116 | 140 | 161 | 0.0895 | 515 | 1.275 | 31.62 | 12.17 | 2 | 0.1543 | 83 | 0.0025 | 70.15 | 6.080 | 0.1560 | 10772.9 | 1460000 | 216000000 | 34000000000 | 0.3272 | 0.2735 | 0.0000 | 0.0000 | 0.0282 | 0.0000 | 0.1338 | 0.0000 | 0.1901 | 0.0198 | 0.1620 | 0.1581 | 0.1268 | 0.1937 | 0.1479 | 0.1621 | 0.1056 | 0.1581 | 0.1056 | 0.3083 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0031 | 0.0131 | 0.0800 | 0.0551 | 0.0985 | 0.0866 | 0.0431 | 0.0525 | 0.1138 | 0.0840 | 0.6585 | 0.7087 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0055 | 0.0000 | 0.0383 | 0.0156 | 0.1038 | 0.1328 | 0.1038 | 0.1016 | 0.1093 | 0.1016 | 0.1421 | 0.1328 | 0.4973 | 0.5000 | 0.0000 | 0.0000 | 0.0078 | 0.0389 | 0.0661 | 0.1128 | 0.0973 | 0.1128 | 0.5642 | 17 | 19 | 20 | 22 | 25 | 35 | 92 | 249 | 645 | 0.1812 | 27.53 | 3.742 | 0.6466 | 118185.0 | 112000000 | 119000000000 | 139000000000000 | 0.7250 | 0.0477 | 0.0600 | 0.0080 | 0.2240 | 0.0282 | 0.3600 | 0.1690 | 0.1600 | 0.1932 | 0.0920 | 0.2012 | 0.0480 | 0.1469 | 0.0240 | 0.1066 | 0.0240 | 0.0624 | 0.0080 | 0.0845 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0020 | 0.0012 | 0.0231 | 0.0168 | 0.0909 | 0.0895 | 0.1324 | 0.1111 | 0.0856 | 0.0847 | 0.1232 | 0.1219 | 0.5422 | 0.5742 | 0.0000 | 0.0000 | 0.0047 | 0.0060 | 0.0087 | 0.0146 | 0.0379 | 0.0368 | 0.0883 | 0.0856 | 0.1270 | 0.1336 | 0.1017 | 0.0967 | 0.1222 | 0.1182 | 0.5095 | 0.5086 | 0.0000 | 0.0000 | 0.0086 | 0.0281 | 0.0944 | 0.1354 | 0.0929 | 0.1218 | 0.5187 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1125 | 641 | 11752 | 25342 | 232.5 | 61.19 | 170.59 | 255.96 | 162 | 186 | 201 | 215 | 228 | 242 | 257 | 278 | 310 | 0.0510 | 1293 | 1.092 | 30.46 | 9.43 | 3 | 0.0062 | 73 | 0.0008 | 52.10 | 7.510 | 0.1713 | 57786.2 | 15300000 | 4280000000 | 1270000000000 | 0.4266 | 0.2087 | 0.0003 | 0.0000 | 0.0011 | 0.0002 | 0.0038 | 0.0004 | 0.0137 | 0.0016 | 0.0570 | 0.0194 | 0.1221 | 0.0376 | 0.1242 | 0.0374 | 0.1725 | 0.0532 | 0.5053 | 0.8503 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0015 | 0.0000 | 0.0056 | 0.0005 | 0.0238 | 0.0113 | 0.0480 | 0.0188 | 0.0513 | 0.0158 | 0.0752 | 0.0235 | 0.7940 | 0.9300 | 0.0039 | 0.0023 | 0.0117 | 0.0081 | 0.0174 | 0.0151 | 0.0516 | 0.0755 | 0.0951 | 0.1231 | 0.1428 | 0.1649 | 0.0872 | 0.1115 | 0.1228 | 0.1161 | 0.4674 | 0.3833 | 0.0018 | 0.0029 | 0.0093 | 0.0250 | 0.0622 | 0.0988 | 0.0949 | 0.1131 | 0.5921 | 9 | 12 | 17 | 32 | 58 | 95 | 152 | 272 | 534 | 0.0689 | 34.29 | 5.267 | 0.5297 | 94612.1 | 77200000 | 75700000000 | 83200000000000 | 0.3585 | 0.3278 | 0.0395 | 0.0012 | 0.1512 | 0.0108 | 0.2256 | 0.0794 | 0.1461 | 0.1072 | 0.1502 | 0.1684 | 0.1169 | 0.1823 | 0.0707 | 0.1281 | 0.0608 | 0.1168 | 0.0390 | 0.2056 | 0.0006 | 0.0003 | 0.0021 | 0.0014 | 0.0038 | 0.0026 | 0.0153 | 0.0136 | 0.0581 | 0.0480 | 0.0869 | 0.0812 | 0.0666 | 0.0586 | 0.0861 | 0.0828 | 0.6805 | 0.7116 | 0.0002 | 0.0007 | 0.0019 | 0.0034 | 0.0056 | 0.0081 | 0.0251 | 0.0236 | 0.0640 | 0.0649 | 0.0941 | 0.0908 | 0.0674 | 0.0685 | 0.0855 | 0.0777 | 0.6563 | 0.6622 | 0.0007 | 0.0013 | 0.0062 | 0.0194 | 0.0623 | 0.0938 | 0.0645 | 0.0859 | 0.6660 | |||
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1133 | 155 | 893 | 1399 | 15.3 | 5.59 | 6.05 | 2.57 | 9 | 11 | 12 | 13 | 14 | 15 | 17 | 19 | 23 | 0.2437 | 341 | 0.631 | 86.21 | 19.03 | 0 | 0.2520 | 225 | 0.0063 | 15.00 | 5.353 | 0.2862 | 266.3 | 5252.12 | 117067 | 2910000 | 0.3793 | 0.2519 | 0.0048 | 0.0028 | 0.0333 | 0.0000 | 0.0643 | 0.0127 | 0.1452 | 0.0325 | 0.1786 | 0.0734 | 0.2262 | 0.0805 | 0.1762 | 0.1427 | 0.1143 | 0.2260 | 0.0571 | 0.4294 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0240 | 0.0059 | 0.0314 | 0.0202 | 0.0569 | 0.0308 | 0.0883 | 0.0403 | 0.1033 | 0.0664 | 0.1856 | 0.1151 | 0.4985 | 0.7212 | 0.0282 | 0.0444 | 0.0726 | 0.0667 | 0.0565 | 0.0963 | 0.0645 | 0.1037 | 0.1089 | 0.0889 | 0.1089 | 0.0963 | 0.1089 | 0.1185 | 0.1573 | 0.1481 | 0.2944 | 0.2370 | 0.0070 | 0.0282 | 0.0446 | 0.0845 | 0.1009 | 0.1056 | 0.1502 | 0.1291 | 0.3498 | 2 | 4 | 4 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0207 | 14.14 | 4.219 | 0.3005 | 43.2 | 342.525 | 2947.43 | 27112.9 | 0.5136 | 0.1528 | 0.0287 | 0.0010 | 0.1396 | 0.0117 | 0.2199 | 0.0321 | 0.2581 | 0.0884 | 0.1893 | 0.1574 | 0.1090 | 0.2235 | 0.0402 | 0.2673 | 0.0134 | 0.1720 | 0.0019 | 0.0466 | 0.0022 | 0.0000 | 0.0151 | 0.0048 | 0.0635 | 0.0032 | 0.1389 | 0.0415 | 0.2099 | 0.0909 | 0.2196 | 0.1085 | 0.2056 | 0.1699 | 0.1044 | 0.2759 | 0.0409 | 0.3054 | 0.1010 | 0.3289 | 0.2241 | 0.3156 | 0.1946 | 0.2089 | 0.1749 | 0.0800 | 0.1626 | 0.0444 | 0.0788 | 0.0222 | 0.0542 | 0.0000 | 0.0099 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0320 | 0.0959 | 0.1337 | 0.2024 | 0.2237 | 0.1787 | 0.0959 | 0.0296 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 963 | 51 | 463 | 2383 | 135.5 | 54.95 | 285.62 | 357.76 | 57 | 79 | 96 | 118 | 140 | 159 | 176 | 191 | 206 | 0.1389 | 331 | 0.806 | 83.49 | 17.80 | 1 | 0.4125 | 191 | 0.0030 | 40.37 | 5.894 | 0.2035 | 21382.7 | 3690000 | 675000000 | 128000000000 | 0.3277 | 0.2693 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0794 | 0.0000 | 0.2063 | 0.0037 | 0.3016 | 0.0967 | 0.2381 | 0.2528 | 0.0952 | 0.1413 | 0.0635 | 0.1450 | 0.0159 | 0.3606 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0066 | 0.0027 | 0.0459 | 0.0495 | 0.1180 | 0.1016 | 0.0525 | 0.0330 | 0.0721 | 0.0549 | 0.7049 | 0.7582 | 0.0000 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0000 | 0.0168 | 0.0947 | 0.0726 | 0.1053 | 0.2123 | 0.2947 | 0.0894 | 0.0526 | 0.1285 | 0.1053 | 0.4804 | 0.3368 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0664 | 0.1286 | 0.0747 | 0.1079 | 0.6100 | 17 | 24 | 32 | 51 | 103 | 203 | 340 | 571 | 860 | 0.0209 | 106.06 | 5.674 | 0.3655 | 209519.0 | 201000000 | 220000000000 | 261000000000000 | 0.5461 | 0.1235 | 0.1000 | 0.0053 | 0.1944 | 0.0317 | 0.2833 | 0.1504 | 0.1389 | 0.1926 | 0.1444 | 0.1636 | 0.0833 | 0.1900 | 0.0444 | 0.0765 | 0.0056 | 0.1187 | 0.0056 | 0.0712 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0169 | 0.0137 | 0.0349 | 0.0235 | 0.0992 | 0.0832 | 0.1680 | 0.1566 | 0.0891 | 0.0861 | 0.1184 | 0.1252 | 0.4724 | 0.5117 | 0.0057 | 0.0016 | 0.0127 | 0.0109 | 0.0255 | 0.0264 | 0.0368 | 0.0358 | 0.0990 | 0.0995 | 0.1457 | 0.1384 | 0.0905 | 0.1151 | 0.1132 | 0.1073 | 0.4710 | 0.4650 | 0.0012 | 0.0037 | 0.0224 | 0.0387 | 0.1110 | 0.1459 | 0.1010 | 0.1035 | 0.4726 | |||
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 334 | 363 | 15302 | 41714 | 244.9 | 60.87 | 131.95 | 179.42 | 171 | 196 | 213 | 227 | 242 | 257 | 273 | 292 | 320 | 0.0338 | 1411 | 0.710 | 67.01 | 10.63 | 1 | 0.0092 | 141 | 0.0009 | 32.33 | 7.369 | 0.2155 | 63663.8 | 17500000 | 5040000000 | 1520000000000 | 0.3811 | 0.2520 | 0.0003 | 0.0001 | 0.0018 | 0.0001 | 0.0054 | 0.0012 | 0.0129 | 0.0025 | 0.0443 | 0.0131 | 0.0775 | 0.0277 | 0.0883 | 0.0259 | 0.1303 | 0.0318 | 0.6391 | 0.8975 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0005 | 0.0043 | 0.0006 | 0.0157 | 0.0082 | 0.0271 | 0.0149 | 0.0311 | 0.0107 | 0.0502 | 0.0147 | 0.8688 | 0.9504 | 0.0040 | 0.0021 | 0.0074 | 0.0094 | 0.0148 | 0.0178 | 0.0415 | 0.0545 | 0.0820 | 0.1027 | 0.1180 | 0.1394 | 0.0981 | 0.1038 | 0.1164 | 0.1153 | 0.5177 | 0.4549 | 0.0010 | 0.0043 | 0.0084 | 0.0193 | 0.0357 | 0.0673 | 0.0704 | 0.0887 | 0.7048 | 13 | 17 | 21 | 29 | 47 | 80 | 136 | 229 | 381 | 0.0427 | 30.07 | 5.192 | 0.5095 | 49598.6 | 28100000 | 20000000000 | 16800000000000 | 0.3211 | 0.3337 | 0.0612 | 0.0021 | 0.1948 | 0.0183 | 0.2759 | 0.1123 | 0.1692 | 0.1501 | 0.1266 | 0.2025 | 0.0897 | 0.1912 | 0.0381 | 0.1170 | 0.0295 | 0.0975 | 0.0151 | 0.1089 | 0.0001 | 0.0001 | 0.0003 | 0.0005 | 0.0017 | 0.0013 | 0.0140 | 0.0104 | 0.0568 | 0.0497 | 0.0959 | 0.0827 | 0.0647 | 0.0548 | 0.0965 | 0.0855 | 0.6699 | 0.7149 | 0.0002 | 0.0004 | 0.0005 | 0.0012 | 0.0029 | 0.0045 | 0.0170 | 0.0211 | 0.0778 | 0.0843 | 0.1185 | 0.1332 | 0.0800 | 0.0874 | 0.1208 | 0.1226 | 0.5822 | 0.5453 | 0.0002 | 0.0013 | 0.0024 | 0.0139 | 0.0650 | 0.1091 | 0.0726 | 0.1074 | 0.6281 | |||
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 987 | 380 | 12791 | 25828 | 244.0 | 56.67 | 95.18 | 198.31 | 177 | 201 | 217 | 230 | 243 | 256 | 271 | 289 | 316 | 0.0428 | 1106 | 0.611 | 50.00 | 6.08 | 2 | 0.0081 | 104 | 0.0009 | 41.29 | 7.385 | 0.1837 | 62748.8 | 16900000 | 4720000000 | 1370000000000 | 0.4150 | 0.2225 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0139 | 0.0020 | 0.0437 | 0.0128 | 0.0935 | 0.0267 | 0.1037 | 0.0271 | 0.1485 | 0.0436 | 0.5911 | 0.8877 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0051 | 0.0007 | 0.0167 | 0.0075 | 0.0370 | 0.0142 | 0.0370 | 0.0105 | 0.0578 | 0.0186 | 0.8443 | 0.9484 | 0.0051 | 0.0074 | 0.0136 | 0.0297 | 0.0230 | 0.0408 | 0.0519 | 0.1169 | 0.0928 | 0.1447 | 0.1328 | 0.1855 | 0.0992 | 0.1039 | 0.1507 | 0.1169 | 0.4308 | 0.2542 | 0.0013 | 0.0041 | 0.0084 | 0.0209 | 0.0523 | 0.0900 | 0.0917 | 0.1156 | 0.6157 | 10 | 11 | 13 | 16 | 19 | 30 | 61 | 128 | 252 | 0.1445 | 34.06 | 4.024 | 0.6355 | 48384.8 | 50100000 | 70500000000 | 115000000000000 | 0.4211 | 0.2561 | 0.0753 | 0.0013 | 0.2507 | 0.0276 | 0.3011 | 0.1619 | 0.1172 | 0.1639 | 0.1051 | 0.2101 | 0.0717 | 0.1905 | 0.0362 | 0.0921 | 0.0291 | 0.0768 | 0.0135 | 0.0758 | 0.0001 | 0.0002 | 0.0003 | 0.0001 | 0.0021 | 0.0012 | 0.0147 | 0.0116 | 0.0679 | 0.0616 | 0.1162 | 0.1005 | 0.0657 | 0.0596 | 0.1024 | 0.0930 | 0.6306 | 0.6721 | 0.0002 | 0.0012 | 0.0012 | 0.0028 | 0.0041 | 0.0058 | 0.0225 | 0.0271 | 0.0797 | 0.0776 | 0.1234 | 0.1387 | 0.0808 | 0.0856 | 0.1154 | 0.1264 | 0.5727 | 0.5349 | 0.0002 | 0.0013 | 0.0034 | 0.0168 | 0.0750 | 0.1186 | 0.0738 | 0.1066 | 0.6045 | |||
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 | |
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 487 | 388 | 17803 | 45389 | 157.0 | 50.28 | 154.36 | 177.24 | 92 | 114 | 128 | 142 | 155 | 168 | 183 | 200 | 225 | 0.0425 | 1928 | 1.251 | 24.52 | 7.81 | 5 | 0.0033 | 58 | 0.0011 | 27.12 | 7.140 | 0.2383 | 27189.4 | 5090000 | 1010000000 | 213000000000 | 0.4282 | 0.2106 | 0.0016 | 0.0001 | 0.0027 | 0.0011 | 0.0080 | 0.0022 | 0.0288 | 0.0083 | 0.0923 | 0.0292 | 0.1552 | 0.0530 | 0.1536 | 0.0615 | 0.1813 | 0.0892 | 0.3764 | 0.7554 | 0.0006 | 0.0001 | 0.0008 | 0.0008 | 0.0020 | 0.0012 | 0.0062 | 0.0038 | 0.0238 | 0.0118 | 0.0466 | 0.0193 | 0.0520 | 0.0202 | 0.0673 | 0.0299 | 0.8006 | 0.9130 | 0.0028 | 0.0076 | 0.0051 | 0.0076 | 0.0145 | 0.0286 | 0.0373 | 0.0753 | 0.0821 | 0.1201 | 0.1345 | 0.1711 | 0.1117 | 0.1287 | 0.1381 | 0.1368 | 0.4740 | 0.3241 | 0.0009 | 0.0019 | 0.0057 | 0.0186 | 0.0505 | 0.0897 | 0.0859 | 0.1121 | 0.6346 | 13 | 18 | 26 | 47 | 81 | 128 | 193 | 278 | 407 | 0.0395 | 20.75 | 5.394 | 0.5005 | 55240.7 | 27700000 | 16900000000 | 11900000000000 | 0.4247 | 0.2143 | 0.0378 | 0.0014 | 0.1492 | 0.0110 | 0.2622 | 0.0683 | 0.1893 | 0.1171 | 0.1504 | 0.1913 | 0.1095 | 0.1978 | 0.0586 | 0.1383 | 0.0341 | 0.1296 | 0.0088 | 0.1451 | 0.0003 | 0.0002 | 0.0011 | 0.0008 | 0.0022 | 0.0018 | 0.0130 | 0.0095 | 0.0518 | 0.0406 | 0.0919 | 0.0720 | 0.0661 | 0.0535 | 0.0987 | 0.0822 | 0.6750 | 0.7394 | 0.0006 | 0.0006 | 0.0012 | 0.0024 | 0.0051 | 0.0080 | 0.0184 | 0.0254 | 0.0735 | 0.0834 | 0.1248 | 0.1314 | 0.0862 | 0.0949 | 0.1190 | 0.1284 | 0.5712 | 0.5254 | 0.0004 | 0.0015 | 0.0030 | 0.0169 | 0.0596 | 0.1071 | 0.0813 | 0.1092 | 0.6210 | |
Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 | |
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 916 | 643 | 6177 | 7967 | 199.4 | 44.34 | 175.07 | 133.71 | 150 | 163 | 173 | 182 | 192 | 203 | 216 | 234 | 259 | 0.0964 | 768 | 0.994 | 106.57 | 33.42 | 1 | 0.0440 | 272 | 0.0013 | 36.60 | 6.944 | 0.1957 | 41711.5 | 9180000 | 2130000000 | 520000000000 | 0.4243 | 0.2275 | 0.0010 | 0.0000 | 0.0007 | 0.0000 | 0.0032 | 0.0000 | 0.0168 | 0.0009 | 0.0753 | 0.0176 | 0.1308 | 0.0425 | 0.1402 | 0.0375 | 0.1836 | 0.0678 | 0.4482 | 0.8336 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0000 | 0.0076 | 0.0005 | 0.0326 | 0.0112 | 0.0591 | 0.0230 | 0.0595 | 0.0150 | 0.0870 | 0.0231 | 0.7518 | 0.9272 | 0.0009 | 0.0179 | 0.0091 | 0.0358 | 0.0174 | 0.0657 | 0.0659 | 0.1343 | 0.1473 | 0.1433 | 0.1738 | 0.1791 | 0.1363 | 0.0955 | 0.1537 | 0.1164 | 0.2955 | 0.2119 | 0.0011 | 0.0033 | 0.0110 | 0.0375 | 0.0824 | 0.1191 | 0.1085 | 0.1393 | 0.4978 | 30 | 56 | 84 | 112 | 145 | 182 | 223 | 277 | 360 | 0.0025 | 69.87 | 6.927 | 0.2586 | 48522.6 | 17600000 | 7750000000 | 3970000000000 | 0.4873 | 0.1778 | 0.0220 | 0.0017 | 0.1111 | 0.0031 | 0.1870 | 0.0584 | 0.1544 | 0.1117 | 0.1816 | 0.1633 | 0.1457 | 0.1879 | 0.0951 | 0.1507 | 0.0552 | 0.1240 | 0.0479 | 0.1992 | 0.0002 | 0.0004 | 0.0014 | 0.0006 | 0.0029 | 0.0018 | 0.0145 | 0.0127 | 0.0737 | 0.0543 | 0.1090 | 0.0980 | 0.0872 | 0.0692 | 0.1206 | 0.1000 | 0.5904 | 0.6629 | 0.0015 | 0.0034 | 0.0019 | 0.0029 | 0.0087 | 0.0147 | 0.0417 | 0.0563 | 0.1059 | 0.1337 | 0.1647 | 0.1768 | 0.1097 | 0.1254 | 0.1514 | 0.1528 | 0.4144 | 0.3340 | 0.0006 | 0.0033 | 0.0072 | 0.0275 | 0.0899 | 0.1341 | 0.1039 | 0.1338 | 0.4997 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1178 | 674 | 5484 | 6809 | 143.9 | 34.02 | 169.15 | 111.62 | 106 | 116 | 124 | 131 | 139 | 147 | 156 | 168 | 188 | 0.1007 | 686 | 1.157 | 112.97 | 41.40 | 1 | 0.0514 | 282 | 0.0021 | 24.63 | 6.515 | 0.2364 | 21871.4 | 3520000 | 604000000 | 111000000000 | 0.4507 | 0.2018 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0058 | 0.0000 | 0.0260 | 0.0006 | 0.0901 | 0.0200 | 0.1435 | 0.0450 | 0.1588 | 0.0427 | 0.1805 | 0.0719 | 0.3939 | 0.8199 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0104 | 0.0000 | 0.0398 | 0.0138 | 0.0659 | 0.0247 | 0.0797 | 0.0192 | 0.1000 | 0.0332 | 0.7008 | 0.9092 | 0.0032 | 0.0155 | 0.0181 | 0.0217 | 0.0288 | 0.0342 | 0.0703 | 0.1025 | 0.1384 | 0.1460 | 0.1853 | 0.2267 | 0.1289 | 0.0932 | 0.1310 | 0.1211 | 0.2961 | 0.2391 | 0.0017 | 0.0041 | 0.0120 | 0.0398 | 0.0915 | 0.1441 | 0.1151 | 0.1416 | 0.4501 | 48 | 70 | 90 | 115 | 144 | 176 | 214 | 261 | 331 | 0.0020 | 39.25 | 6.753 | 0.2608 | 41068.8 | 12600000 | 4490000000 | 1800000000000 | 0.5577 | 0.1336 | 0.0189 | 0.0007 | 0.0769 | 0.0043 | 0.1858 | 0.0340 | 0.1829 | 0.0814 | 0.2010 | 0.1571 | 0.1647 | 0.2049 | 0.0885 | 0.1545 | 0.0508 | 0.1578 | 0.0305 | 0.2052 | 0.0008 | 0.0000 | 0.0022 | 0.0007 | 0.0047 | 0.0045 | 0.0230 | 0.0137 | 0.0604 | 0.0531 | 0.1187 | 0.0871 | 0.0787 | 0.0745 | 0.1281 | 0.1004 | 0.5833 | 0.6661 | 0.0022 | 0.0048 | 0.0049 | 0.0048 | 0.0153 | 0.0137 | 0.0431 | 0.0642 | 0.0969 | 0.1220 | 0.1620 | 0.1803 | 0.1184 | 0.1214 | 0.1463 | 0.1642 | 0.4109 | 0.3248 | 0.0017 | 0.0017 | 0.0098 | 0.0258 | 0.0834 | 0.1386 | 0.0988 | 0.1449 | 0.4951 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 120 | 655 | 4898 | 6342 | 156.3 | 38.66 | 125.03 | 113.06 | 113 | 124 | 133 | 141 | 150 | 159 | 170 | 185 | 209 | 0.1042 | 661 | 1.120 | 87.09 | 35.00 | 2 | 0.0484 | 237 | 0.0016 | 33.19 | 6.724 | 0.2162 | 25917.2 | 4580000 | 862000000 | 173000000000 | 0.4020 | 0.2430 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0004 | 0.0371 | 0.0011 | 0.0856 | 0.0217 | 0.1540 | 0.0539 | 0.1540 | 0.0479 | 0.1891 | 0.0811 | 0.3701 | 0.7938 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0144 | 0.0004 | 0.0394 | 0.0127 | 0.0737 | 0.0281 | 0.0709 | 0.0168 | 0.1057 | 0.0388 | 0.6924 | 0.9028 | 0.0088 | 0.0056 | 0.0110 | 0.0056 | 0.0154 | 0.0504 | 0.0647 | 0.1148 | 0.1283 | 0.1961 | 0.1776 | 0.1905 | 0.1217 | 0.0812 | 0.1371 | 0.1204 | 0.3355 | 0.2353 | 0.0014 | 0.0066 | 0.0132 | 0.0448 | 0.0754 | 0.1273 | 0.1056 | 0.1165 | 0.5092 | 23 | 33 | 47 | 65 | 89 | 116 | 152 | 201 | 280 | 0.0060 | 36.94 | 6.174 | 0.3498 | 28413.7 | 9100000 | 3580000000 | 1620000000000 | 0.5069 | 0.1440 | 0.0282 | 0.0015 | 0.0796 | 0.0149 | 0.1823 | 0.0412 | 0.2034 | 0.0865 | 0.1601 | 0.1370 | 0.1511 | 0.1885 | 0.0987 | 0.1555 | 0.0564 | 0.1529 | 0.0403 | 0.2219 | 0.0014 | 0.0006 | 0.0003 | 0.0023 | 0.0061 | 0.0020 | 0.0215 | 0.0159 | 0.0617 | 0.0456 | 0.1159 | 0.0901 | 0.0829 | 0.0697 | 0.1265 | 0.1079 | 0.5837 | 0.6661 | 0.0015 | 0.0031 | 0.0077 | 0.0057 | 0.0113 | 0.0088 | 0.0381 | 0.0453 | 0.0959 | 0.1246 | 0.1562 | 0.1724 | 0.1113 | 0.1089 | 0.1572 | 0.1605 | 0.4206 | 0.3707 | 0.0004 | 0.0033 | 0.0075 | 0.0263 | 0.0889 | 0.1369 | 0.1039 | 0.1507 | 0.4821 |