High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1226 | 292 | 1447 | 9024 | 65.1 | 24.28 | 181.44 | 210.82 | 35 | 44 | 51 | 57 | 63 | 69 | 76 | 85 | 96 | 0.0659 | 595 | 0.521 | 83.49 | 16.03 | 5 | 0.1714 | 248 | 0.0021 | 31.10 | 6.361 | 0.2003 | 4823.6 | 400876 | 37000000 | 3760000000 | 0.3867 | 0.2406 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0198 | 0.0028 | 0.0843 | 0.0170 | 0.1802 | 0.0405 | 0.2215 | 0.1008 | 0.1884 | 0.1329 | 0.1818 | 0.1951 | 0.1124 | 0.5108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0016 | 0.0109 | 0.0095 | 0.0465 | 0.0247 | 0.0812 | 0.0366 | 0.0663 | 0.0461 | 0.1238 | 0.0700 | 0.6693 | 0.8115 | 0.0049 | 0.0255 | 0.0099 | 0.0204 | 0.0025 | 0.0510 | 0.0765 | 0.1071 | 0.1284 | 0.1837 | 0.1778 | 0.1735 | 0.1654 | 0.1173 | 0.1407 | 0.1378 | 0.2938 | 0.1837 | 0.0015 | 0.0029 | 0.0059 | 0.0322 | 0.1025 | 0.1259 | 0.1127 | 0.1347 | 0.4817 | 19 | 26 | 41 | 64 | 97 | 142 | 205 | 308 | 477 | 0.0338 | 9.96 | 5.000 | 0.5659 | 77361.5 | 47900000 | 36100000000 | 30600000000000 | 0.5191 | 0.1524 | 0.0220 | 0.0015 | 0.0828 | 0.0094 | 0.1118 | 0.0342 | 0.1577 | 0.0768 | 0.2126 | 0.1412 | 0.1427 | 0.1684 | 0.1228 | 0.1273 | 0.0918 | 0.1446 | 0.0559 | 0.2967 | 0.0006 | 0.0005 | 0.0025 | 0.0012 | 0.0034 | 0.0009 | 0.0104 | 0.0092 | 0.0533 | 0.0431 | 0.0855 | 0.0726 | 0.0676 | 0.0528 | 0.0917 | 0.0820 | 0.6851 | 0.7378 | 0.0008 | 0.0013 | 0.0027 | 0.0022 | 0.0059 | 0.0040 | 0.0164 | 0.0211 | 0.0632 | 0.0723 | 0.1096 | 0.1159 | 0.0780 | 0.0858 | 0.1166 | 0.1204 | 0.6069 | 0.5768 | 0.0003 | 0.0020 | 0.0043 | 0.0143 | 0.0627 | 0.0953 | 0.0720 | 0.1040 | 0.6450 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 818 | 411 | 1111 | 7364 | 67.7 | 19.08 | 51.50 | 75.73 | 43 | 51 | 58 | 63 | 67 | 72 | 77 | 83 | 92 | 0.0743 | 547 | 0.895 | 205.46 | 68.66 | 1 | 0.5041 | 560 | 0.0025 | 26.29 | 6.146 | 0.2030 | 4951.3 | 386036 | 31800000 | 2760000000 | 0.4919 | 0.1558 | 0.0017 | 0.0000 | 0.0084 | 0.0000 | 0.0506 | 0.0042 | 0.0759 | 0.0116 | 0.1433 | 0.0582 | 0.1855 | 0.0857 | 0.1484 | 0.1228 | 0.2024 | 0.1185 | 0.1838 | 0.5989 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0237 | 0.0078 | 0.0580 | 0.0447 | 0.1018 | 0.0438 | 0.0994 | 0.0720 | 0.1515 | 0.0730 | 0.5657 | 0.7588 | 0.0198 | 0.0241 | 0.0238 | 0.0361 | 0.0437 | 0.1566 | 0.1032 | 0.2289 | 0.1468 | 0.1325 | 0.2103 | 0.1687 | 0.1071 | 0.0602 | 0.1151 | 0.0482 | 0.2302 | 0.1446 | 0.0000 | 0.0036 | 0.0163 | 0.0470 | 0.1501 | 0.1410 | 0.1338 | 0.1591 | 0.3490 | 15 | 17 | 18 | 21 | 24 | 29 | 39 | 59 | 117 | 0.2303 | 3.57 | 2.698 | 0.7805 | 8387.2 | 2780000 | 1260000000 | 683000000000 | 0.4695 | 0.1988 | 0.0338 | 0.0076 | 0.1132 | 0.0146 | 0.2294 | 0.0419 | 0.1779 | 0.1017 | 0.1647 | 0.1773 | 0.1250 | 0.1919 | 0.0632 | 0.1582 | 0.0662 | 0.1264 | 0.0265 | 0.1804 | 0.0057 | 0.0035 | 0.0047 | 0.0053 | 0.0095 | 0.0114 | 0.0218 | 0.0252 | 0.0816 | 0.0650 | 0.1044 | 0.0919 | 0.0745 | 0.0831 | 0.1144 | 0.1136 | 0.5833 | 0.6010 | 0.0007 | 0.0016 | 0.0042 | 0.0032 | 0.0049 | 0.0048 | 0.0329 | 0.0322 | 0.0988 | 0.0893 | 0.1142 | 0.1376 | 0.0883 | 0.0837 | 0.1065 | 0.1255 | 0.5494 | 0.5221 | 0.0029 | 0.0041 | 0.0088 | 0.0269 | 0.0779 | 0.1265 | 0.0715 | 0.1154 | 0.5659 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 202 | 300 | 6785 | 14162 | 73.6 | 17.99 | 128.75 | 204.22 | 55 | 60 | 64 | 67 | 70 | 74 | 78 | 85 | 98 | 0.0703 | 996 | 0.964 | 72.80 | 24.35 | 1 | 0.0280 | 190 | 0.0034 | 16.24 | 6.105 | 0.2850 | 5739.9 | 477688 | 42700000 | 4120000000 | 0.4408 | 0.2110 | 0.0005 | 0.0000 | 0.0039 | 0.0005 | 0.0122 | 0.0021 | 0.0270 | 0.0047 | 0.0766 | 0.0226 | 0.1354 | 0.0389 | 0.1541 | 0.0501 | 0.2125 | 0.0784 | 0.3779 | 0.8028 | 0.0002 | 0.0000 | 0.0015 | 0.0001 | 0.0044 | 0.0000 | 0.0115 | 0.0003 | 0.0412 | 0.0127 | 0.0738 | 0.0228 | 0.0842 | 0.0195 | 0.1337 | 0.0408 | 0.6495 | 0.9038 | 0.0089 | 0.0082 | 0.0124 | 0.0392 | 0.0231 | 0.0351 | 0.0738 | 0.1072 | 0.1120 | 0.1691 | 0.1431 | 0.1794 | 0.1182 | 0.1381 | 0.1476 | 0.1196 | 0.3609 | 0.2041 | 0.0051 | 0.0116 | 0.0260 | 0.0619 | 0.0952 | 0.1284 | 0.1208 | 0.1302 | 0.4208 | 12 | 14 | 16 | 19 | 29 | 64 | 131 | 219 | 365 | 0.0796 | 32.45 | 4.690 | 0.5502 | 58277.5 | 46900000 | 56200000000 | 88300000000000 | 0.5837 | 0.1324 | 0.0408 | 0.0021 | 0.1841 | 0.0191 | 0.2326 | 0.0908 | 0.1830 | 0.1300 | 0.1709 | 0.1990 | 0.1158 | 0.1879 | 0.0364 | 0.1423 | 0.0254 | 0.1147 | 0.0110 | 0.1141 | 0.0008 | 0.0004 | 0.0008 | 0.0017 | 0.0017 | 0.0017 | 0.0080 | 0.0075 | 0.0431 | 0.0368 | 0.0772 | 0.0632 | 0.0574 | 0.0462 | 0.1056 | 0.0896 | 0.7054 | 0.7529 | 0.0008 | 0.0006 | 0.0008 | 0.0020 | 0.0029 | 0.0050 | 0.0130 | 0.0190 | 0.0619 | 0.0781 | 0.1060 | 0.1085 | 0.0824 | 0.0930 | 0.1331 | 0.1355 | 0.5993 | 0.5582 | 0.0000 | 0.0009 | 0.0016 | 0.0108 | 0.0498 | 0.0912 | 0.0683 | 0.1170 | 0.6604 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 309 | 735 | 1819 | 14901 | 73.2 | 15.19 | 136.21 | 157.45 | 56 | 62 | 65 | 67 | 70 | 74 | 79 | 85 | 94 | 0.0571 | 851 | 0.961 | 66.85 | 20.22 | 3 | 0.0995 | 181 | 0.0042 | 13.83 | 5.799 | 0.2858 | 5584.7 | 444991 | 37000000 | 3220000000 | 0.5015 | 0.1554 | 0.0008 | 0.0000 | 0.0047 | 0.0006 | 0.0228 | 0.0012 | 0.0417 | 0.0140 | 0.1133 | 0.0450 | 0.1707 | 0.1040 | 0.1526 | 0.0900 | 0.1794 | 0.1244 | 0.3139 | 0.6209 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0069 | 0.0011 | 0.0202 | 0.0117 | 0.0656 | 0.0362 | 0.1040 | 0.0841 | 0.0807 | 0.0523 | 0.1230 | 0.0885 | 0.5984 | 0.7255 | 0.0095 | 0.0238 | 0.0063 | 0.0357 | 0.0381 | 0.1190 | 0.1175 | 0.2381 | 0.1460 | 0.1905 | 0.2190 | 0.1429 | 0.1238 | 0.0833 | 0.1143 | 0.0833 | 0.2254 | 0.0833 | 0.0025 | 0.0135 | 0.0197 | 0.0492 | 0.1095 | 0.1365 | 0.1267 | 0.1501 | 0.3924 | 14 | 17 | 23 | 40 | 73 | 110 | 160 | 243 | 367 | 0.0319 | 18.03 | 5.311 | 0.4923 | 43340.4 | 19300000 | 10300000000 | 6180000000000 | 0.4512 | 0.1992 | 0.0348 | 0.0006 | 0.1211 | 0.0135 | 0.2124 | 0.0737 | 0.1696 | 0.0995 | 0.1621 | 0.1575 | 0.1286 | 0.1894 | 0.0776 | 0.1317 | 0.0547 | 0.1357 | 0.0391 | 0.1983 | 0.0008 | 0.0000 | 0.0012 | 0.0006 | 0.0050 | 0.0021 | 0.0163 | 0.0107 | 0.0553 | 0.0478 | 0.0947 | 0.0811 | 0.0696 | 0.0552 | 0.0962 | 0.0929 | 0.6610 | 0.7096 | 0.0009 | 0.0008 | 0.0018 | 0.0024 | 0.0075 | 0.0050 | 0.0218 | 0.0214 | 0.0693 | 0.0833 | 0.1160 | 0.1303 | 0.0869 | 0.0844 | 0.1141 | 0.1295 | 0.5816 | 0.5430 | 0.0008 | 0.0010 | 0.0031 | 0.0189 | 0.0617 | 0.1060 | 0.0742 | 0.1094 | 0.6249 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 735 | 406 | 428 | 1601 | 77.0 | 10.85 | 11.27 | 14.00 | 65 | 67 | 70 | 72 | 75 | 77 | 82 | 86 | 93 | 0.1643 | 263 | 0.708 | 113.88 | 25.02 | 1 | 0.6636 | 284 | 0.0441 | 1.02 | 3.411 | 0.6516 | 6040.7 | 483894 | 39600000 | 3310000000 | 0.3996 | 0.2382 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0053 | 0.0024 | 0.0718 | 0.0447 | 0.1011 | 0.0753 | 0.0638 | 0.0400 | 0.1277 | 0.0918 | 0.6303 | 0.7435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0047 | 0.0023 | 0.0498 | 0.0444 | 0.0687 | 0.0724 | 0.0332 | 0.0304 | 0.0782 | 0.0748 | 0.7654 | 0.7734 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 1.0000 | 0.0217 | 0.0000 | 0.1739 | 0.0000 | 0.1304 | 0.0000 | 0.1304 | 0.0000 | 0.1522 | 0.0000 | 0.3478 | 0.0000 | 0.0053 | 0.0000 | 0.0105 | 0.0474 | 0.0579 | 0.1000 | 0.0947 | 0.1263 | 0.5579 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 12 | 15 | 0.6009 | 2.10 | 1.178 | 0.8849 | 322.9 | 27681.3 | 3820000 | 619000000 | 0.6572 | 0.0788 | 0.0682 | 0.0020 | 0.1326 | 0.0188 | 0.1111 | 0.0683 | 0.1189 | 0.0960 | 0.1598 | 0.1317 | 0.1774 | 0.1545 | 0.1365 | 0.1535 | 0.0741 | 0.1723 | 0.0214 | 0.2030 | 0.0477 | 0.0017 | 0.0846 | 0.0145 | 0.0682 | 0.0513 | 0.0628 | 0.0803 | 0.1010 | 0.1103 | 0.1173 | 0.1350 | 0.1119 | 0.1325 | 0.1364 | 0.1556 | 0.2701 | 0.3188 | 0.0591 | 0.0313 | 0.0727 | 0.0313 | 0.0364 | 0.0313 | 0.0591 | 0.0625 | 0.0773 | 0.1188 | 0.1545 | 0.1688 | 0.1364 | 0.1813 | 0.1909 | 0.2125 | 0.2136 | 0.1625 | 0.0592 | 0.0547 | 0.0661 | 0.0957 | 0.1207 | 0.1276 | 0.1116 | 0.1344 | 0.2301 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 124 | 725 | 2122 | 76.0 | 19.18 | 87.85 | 150.35 | 55 | 62 | 66 | 70 | 74 | 78 | 82 | 89 | 98 | 0.1555 | 330 | 1.062 | 83.67 | 27.73 | 1 | 0.3007 | 218 | 0.0059 | 12.27 | 5.382 | 0.3021 | 6143.7 | 529049 | 48700000 | 4800000000 | 0.4598 | 0.1774 | 0.0021 | 0.0000 | 0.0105 | 0.0000 | 0.0316 | 0.0062 | 0.0547 | 0.0170 | 0.1116 | 0.0602 | 0.1495 | 0.0802 | 0.1558 | 0.0725 | 0.1811 | 0.1065 | 0.3032 | 0.6574 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0100 | 0.0014 | 0.0067 | 0.0029 | 0.0585 | 0.0432 | 0.1137 | 0.0748 | 0.0870 | 0.0489 | 0.1421 | 0.0691 | 0.5803 | 0.7597 | 0.0081 | 0.0213 | 0.0488 | 0.0000 | 0.0407 | 0.0638 | 0.0894 | 0.1489 | 0.2602 | 0.2340 | 0.1057 | 0.2340 | 0.1545 | 0.0638 | 0.1463 | 0.0851 | 0.1463 | 0.1489 | 0.0000 | 0.0030 | 0.0302 | 0.0604 | 0.1329 | 0.1813 | 0.1390 | 0.1601 | 0.2931 | 14 | 17 | 20 | 25 | 38 | 53 | 73 | 106 | 191 | 0.0472 | 42.92 | 4.329 | 0.5495 | 30310.8 | 21700000 | 20800000000 | 23000000000000 | 0.5356 | 0.1304 | 0.0400 | 0.0000 | 0.1778 | 0.0200 | 0.1689 | 0.0798 | 0.2267 | 0.1098 | 0.1289 | 0.1377 | 0.1333 | 0.1896 | 0.0978 | 0.1337 | 0.0178 | 0.1018 | 0.0089 | 0.2275 | 0.0015 | 0.0000 | 0.0122 | 0.0000 | 0.0198 | 0.0141 | 0.0517 | 0.0387 | 0.0836 | 0.0810 | 0.1049 | 0.1244 | 0.1094 | 0.0845 | 0.1261 | 0.1315 | 0.4909 | 0.5258 | 0.0000 | 0.0028 | 0.0139 | 0.0057 | 0.0254 | 0.0256 | 0.0647 | 0.0427 | 0.1062 | 0.1225 | 0.1201 | 0.1595 | 0.1178 | 0.0798 | 0.1293 | 0.1681 | 0.4226 | 0.3932 | 0.0019 | 0.0130 | 0.0093 | 0.0484 | 0.1043 | 0.1229 | 0.0987 | 0.1378 | 0.4637 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 870 | 152 | 2506 | 5703 | 72.8 | 23.73 | 226.65 | 206.12 | 44 | 52 | 59 | 65 | 71 | 77 | 83 | 92 | 106 | 0.1012 | 577 | 0.226 | 301.04 | 33.94 | 3 | 0.4254 | 1066 | 0.0017 | 34.53 | 6.624 | 0.1875 | 5856.8 | 514772 | 48800000 | 4950000000 | 0.4100 | 0.2367 | 0.0000 | 0.0000 | 0.0094 | 0.0000 | 0.0309 | 0.0015 | 0.0738 | 0.0082 | 0.1639 | 0.0494 | 0.1966 | 0.0937 | 0.1949 | 0.1105 | 0.1768 | 0.1549 | 0.1536 | 0.5818 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0009 | 0.0147 | 0.0035 | 0.0548 | 0.0288 | 0.0892 | 0.0399 | 0.0926 | 0.0465 | 0.1242 | 0.0798 | 0.6222 | 0.8005 | 0.0050 | 0.0068 | 0.0149 | 0.0068 | 0.0215 | 0.0375 | 0.0809 | 0.1024 | 0.1601 | 0.2321 | 0.1700 | 0.1945 | 0.1221 | 0.1229 | 0.1535 | 0.1468 | 0.2723 | 0.1502 | 0.0017 | 0.0025 | 0.0142 | 0.0418 | 0.0879 | 0.1431 | 0.1305 | 0.1423 | 0.4360 | 33 | 48 | 74 | 110 | 160 | 220 | 294 | 390 | 525 | 0.0110 | 30.01 | 5.917 | 0.3620 | 93846.7 | 52100000 | 34500000000 | 25800000000000 | 0.5031 | 0.1657 | 0.0592 | 0.0019 | 0.2513 | 0.0205 | 0.2592 | 0.1189 | 0.1526 | 0.1841 | 0.1079 | 0.1937 | 0.0921 | 0.1688 | 0.0434 | 0.1119 | 0.0224 | 0.0985 | 0.0118 | 0.1017 | 0.0000 | 0.0000 | 0.0023 | 0.0013 | 0.0080 | 0.0035 | 0.0221 | 0.0190 | 0.0865 | 0.0723 | 0.1319 | 0.1138 | 0.1021 | 0.0826 | 0.1444 | 0.1157 | 0.5027 | 0.5919 | 0.0011 | 0.0026 | 0.0038 | 0.0026 | 0.0145 | 0.0168 | 0.0376 | 0.0510 | 0.1175 | 0.1395 | 0.1760 | 0.1802 | 0.1180 | 0.1298 | 0.1352 | 0.1486 | 0.3965 | 0.3288 | 0.0009 | 0.0018 | 0.0086 | 0.0378 | 0.0991 | 0.1535 | 0.1153 | 0.1346 | 0.4484 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 274 | 223 | 6457 | 17021 | 77.3 | 19.26 | 210.94 | 213.95 | 57 | 61 | 66 | 70 | 74 | 78 | 84 | 91 | 103 | 0.0644 | 1096 | 0.843 | 90.43 | 26.17 | 1 | 0.0367 | 237 | 0.0028 | 17.12 | 6.228 | 0.2745 | 6348.3 | 556064 | 52200000 | 5250000000 | 0.4510 | 0.1996 | 0.0010 | 0.0000 | 0.0056 | 0.0003 | 0.0133 | 0.0005 | 0.0380 | 0.0061 | 0.0745 | 0.0225 | 0.1425 | 0.0484 | 0.1711 | 0.0522 | 0.2152 | 0.0849 | 0.3389 | 0.7851 | 0.0004 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0000 | 0.0163 | 0.0020 | 0.0342 | 0.0138 | 0.0671 | 0.0273 | 0.0778 | 0.0218 | 0.1102 | 0.0414 | 0.6848 | 0.8935 | 0.0074 | 0.0130 | 0.0197 | 0.0216 | 0.0303 | 0.0670 | 0.0663 | 0.1058 | 0.1286 | 0.1685 | 0.1335 | 0.1598 | 0.1179 | 0.1102 | 0.1605 | 0.1102 | 0.3358 | 0.2441 | 0.0024 | 0.0094 | 0.0171 | 0.0447 | 0.0765 | 0.1024 | 0.1080 | 0.1279 | 0.5114 | 18 | 30 | 63 | 104 | 145 | 194 | 257 | 356 | 511 | 0.0108 | 28.47 | 6.188 | 0.3938 | 90266.1 | 55800000 | 45300000000 | 46700000000000 | 0.5019 | 0.1685 | 0.0158 | 0.0008 | 0.0801 | 0.0060 | 0.1780 | 0.0286 | 0.1711 | 0.0730 | 0.1885 | 0.1548 | 0.1561 | 0.2064 | 0.0991 | 0.1523 | 0.0752 | 0.1528 | 0.0360 | 0.2253 | 0.0009 | 0.0001 | 0.0013 | 0.0006 | 0.0042 | 0.0030 | 0.0144 | 0.0093 | 0.0568 | 0.0438 | 0.0954 | 0.0772 | 0.0796 | 0.0684 | 0.1057 | 0.0967 | 0.6416 | 0.7008 | 0.0013 | 0.0018 | 0.0031 | 0.0027 | 0.0098 | 0.0098 | 0.0233 | 0.0219 | 0.0729 | 0.0825 | 0.1141 | 0.1324 | 0.0873 | 0.0882 | 0.1187 | 0.1185 | 0.5694 | 0.5421 | 0.0022 | 0.0021 | 0.0062 | 0.0230 | 0.0643 | 0.1045 | 0.0826 | 0.1072 | 0.6079 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1270 | 935 | 2332 | 2784 | 77.0 | 17.41 | 147.31 | 171.19 | 57 | 63 | 67 | 71 | 75 | 79 | 84 | 90 | 98 | 0.1566 | 436 | 0.850 | 77.94 | 29.70 | 1 | 0.1038 | 242 | 0.0063 | 9.67 | 5.383 | 0.3501 | 6226.1 | 531430 | 48100000 | 4640000000 | 0.4627 | 0.1874 | 0.0013 | 0.0000 | 0.0038 | 0.0005 | 0.0089 | 0.0014 | 0.0335 | 0.0046 | 0.0772 | 0.0246 | 0.1392 | 0.0483 | 0.1512 | 0.0433 | 0.1980 | 0.0724 | 0.3871 | 0.8050 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0031 | 0.0000 | 0.0098 | 0.0013 | 0.0411 | 0.0183 | 0.0878 | 0.0404 | 0.0734 | 0.0243 | 0.1145 | 0.0469 | 0.6689 | 0.8688 | 0.0109 | 0.0189 | 0.0327 | 0.0189 | 0.0463 | 0.0566 | 0.1308 | 0.1509 | 0.1417 | 0.1887 | 0.1989 | 0.2264 | 0.1144 | 0.0943 | 0.1608 | 0.1321 | 0.1635 | 0.1132 | 0.0028 | 0.0123 | 0.0274 | 0.0482 | 0.1154 | 0.1703 | 0.1060 | 0.1552 | 0.3623 | 13 | 16 | 21 | 34 | 74 | 129 | 190 | 273 | 377 | 0.0284 | 57.62 | 5.532 | 0.4008 | 50997.4 | 24600000 | 14500000000 | 9660000000000 | 0.5052 | 0.1542 | 0.0789 | 0.0074 | 0.2366 | 0.0391 | 0.2258 | 0.1657 | 0.1075 | 0.1304 | 0.1004 | 0.1657 | 0.1183 | 0.1657 | 0.0824 | 0.1229 | 0.0323 | 0.0838 | 0.0179 | 0.1192 | 0.0017 | 0.0000 | 0.0017 | 0.0008 | 0.0051 | 0.0084 | 0.0146 | 0.0114 | 0.0788 | 0.0729 | 0.1311 | 0.1109 | 0.0874 | 0.0858 | 0.1482 | 0.1291 | 0.5313 | 0.5809 | 0.0011 | 0.0000 | 0.0045 | 0.0064 | 0.0124 | 0.0141 | 0.0236 | 0.0295 | 0.1025 | 0.1013 | 0.1577 | 0.1782 | 0.1092 | 0.1115 | 0.1441 | 0.1449 | 0.4448 | 0.4141 | 0.0020 | 0.0039 | 0.0039 | 0.0225 | 0.1000 | 0.1324 | 0.1049 | 0.1471 | 0.4833 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 944 | 643 | 10766 | 25398 | 77.7 | 26.50 | 79.35 | 104.73 | 50 | 58 | 63 | 68 | 73 | 79 | 85 | 93 | 108 | 0.0568 | 1442 | 1.039 | 62.30 | 19.70 | 12 | 0.0144 | 155 | 0.0021 | 19.33 | 6.548 | 0.2687 | 6739.6 | 660302 | 73500000 | 9260000000 | 0.4514 | 0.1914 | 0.0004 | 0.0001 | 0.0041 | 0.0004 | 0.0155 | 0.0014 | 0.0404 | 0.0069 | 0.0933 | 0.0282 | 0.1426 | 0.0518 | 0.1465 | 0.0640 | 0.1811 | 0.0814 | 0.3762 | 0.7657 | 0.0003 | 0.0000 | 0.0017 | 0.0001 | 0.0045 | 0.0006 | 0.0160 | 0.0048 | 0.0422 | 0.0180 | 0.0703 | 0.0309 | 0.0638 | 0.0353 | 0.1024 | 0.0473 | 0.6987 | 0.8630 | 0.0039 | 0.0067 | 0.0111 | 0.0183 | 0.0261 | 0.0202 | 0.0623 | 0.0577 | 0.1044 | 0.0876 | 0.1358 | 0.1107 | 0.0894 | 0.0808 | 0.1049 | 0.1078 | 0.4621 | 0.5101 | 0.0018 | 0.0078 | 0.0155 | 0.0331 | 0.0750 | 0.0992 | 0.0965 | 0.1223 | 0.5488 | 24 | 27 | 31 | 34 | 39 | 47 | 64 | 99 | 187 | 0.1253 | 4.89 | 3.514 | 0.7026 | 17262.9 | 7360000 | 4380000000 | 3170000000000 | 0.5875 | 0.1331 | 0.0281 | 0.0053 | 0.1260 | 0.0156 | 0.1868 | 0.0425 | 0.1366 | 0.0966 | 0.1545 | 0.1560 | 0.1417 | 0.1683 | 0.1034 | 0.1305 | 0.0757 | 0.1316 | 0.0472 | 0.2536 | 0.0005 | 0.0026 | 0.0029 | 0.0056 | 0.0074 | 0.0082 | 0.0218 | 0.0211 | 0.0702 | 0.0565 | 0.0928 | 0.0744 | 0.0750 | 0.0686 | 0.1091 | 0.0987 | 0.6202 | 0.6644 | 0.0015 | 0.0009 | 0.0017 | 0.0024 | 0.0077 | 0.0079 | 0.0283 | 0.0323 | 0.0924 | 0.0996 | 0.1194 | 0.1287 | 0.0811 | 0.0910 | 0.1267 | 0.1337 | 0.5411 | 0.5034 | 0.0002 | 0.0021 | 0.0070 | 0.0280 | 0.0826 | 0.1089 | 0.0754 | 0.1199 | 0.5761 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 974 | 491 | 2075 | 6138 | 79.2 | 16.85 | 226.62 | 224.68 | 59 | 65 | 70 | 74 | 77 | 82 | 86 | 93 | 102 | 0.0632 | 388 | 0.768 | 127.88 | 34.79 | 1 | 0.1566 | 325 | 0.0032 | 15.64 | 6.011 | 0.2726 | 6562.2 | 567309 | 51100000 | 4800000000 | 0.4688 | 0.1916 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0073 | 0.0005 | 0.0278 | 0.0010 | 0.0805 | 0.0234 | 0.1426 | 0.0426 | 0.1500 | 0.0483 | 0.2004 | 0.0701 | 0.3899 | 0.8141 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0063 | 0.0000 | 0.0322 | 0.0138 | 0.0679 | 0.0256 | 0.0621 | 0.0177 | 0.1059 | 0.0290 | 0.7238 | 0.9140 | 0.0081 | 0.0370 | 0.0270 | 0.0278 | 0.0377 | 0.0926 | 0.0916 | 0.0833 | 0.1456 | 0.1759 | 0.1806 | 0.2407 | 0.1294 | 0.1204 | 0.1240 | 0.1852 | 0.2561 | 0.0370 | 0.0030 | 0.0071 | 0.0163 | 0.0346 | 0.0925 | 0.1209 | 0.1189 | 0.1423 | 0.4644 | 24 | 43 | 68 | 98 | 138 | 204 | 294 | 397 | 550 | 0.0072 | 49.76 | 6.356 | 0.3422 | 101826.0 | 62200000 | 45000000000 | 36400000000000 | 0.4500 | 0.1910 | 0.0311 | 0.0000 | 0.1627 | 0.0071 | 0.2825 | 0.0767 | 0.1686 | 0.1526 | 0.1361 | 0.1859 | 0.1124 | 0.2314 | 0.0503 | 0.1313 | 0.0355 | 0.0987 | 0.0207 | 0.1164 | 0.0008 | 0.0000 | 0.0023 | 0.0013 | 0.0011 | 0.0016 | 0.0106 | 0.0107 | 0.0513 | 0.0417 | 0.1124 | 0.1059 | 0.0724 | 0.0672 | 0.1116 | 0.0820 | 0.6376 | 0.6897 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0056 | 0.0077 | 0.0192 | 0.0195 | 0.0709 | 0.0936 | 0.1478 | 0.1647 | 0.1063 | 0.1043 | 0.1184 | 0.1345 | 0.5314 | 0.4716 | 0.0004 | 0.0013 | 0.0053 | 0.0149 | 0.0605 | 0.1329 | 0.0925 | 0.1136 | 0.5785 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1041 | 916 | 403 | 1181 | 80.5 | 10.16 | 173.50 | 253.63 | 67 | 70 | 74 | 77 | 80 | 84 | 86 | 90 | 94 | 0.2320 | 274 | 1.030 | 30.08 | 8.00 | 0 | 0.1762 | 71 | 0.1226 | 0.50 | 2.391 | 0.7876 | 6578.3 | 546175 | 46000000 | 3940000000 | 0.3807 | 0.2394 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0188 | 0.0124 | 0.0591 | 0.0422 | 0.1237 | 0.1166 | 0.1022 | 0.0422 | 0.1532 | 0.0794 | 0.5376 | 0.7072 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0176 | 0.0124 | 0.0403 | 0.0422 | 0.1159 | 0.1166 | 0.0554 | 0.0422 | 0.0781 | 0.0794 | 0.6902 | 0.7072 | 0.0800 | 0.0000 | 0.0800 | 0.0000 | 0.0000 | 0.0000 | 0.2000 | 0.0000 | 0.1200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0048 | 0.0000 | 0.0144 | 0.0383 | 0.1005 | 0.1340 | 0.0861 | 0.1627 | 0.4593 | 19 | 27 | 36 | 48 | 66 | 100 | 161 | 254 | 474 | 0.0380 | 54.53 | 4.632 | 0.4971 | 94375.3 | 84600000 | 95200000000 | 121000000000000 | 0.4414 | 0.1907 | 0.1038 | 0.0045 | 0.2264 | 0.0588 | 0.2170 | 0.1810 | 0.0472 | 0.1267 | 0.1415 | 0.2262 | 0.1321 | 0.1765 | 0.0943 | 0.0679 | 0.0189 | 0.0498 | 0.0189 | 0.1086 | 0.0000 | 0.0000 | 0.0026 | 0.0021 | 0.0026 | 0.0043 | 0.0490 | 0.0322 | 0.1108 | 0.1052 | 0.2010 | 0.1824 | 0.1031 | 0.0966 | 0.1237 | 0.1223 | 0.4072 | 0.4549 | 0.0035 | 0.0041 | 0.0142 | 0.0122 | 0.0284 | 0.0245 | 0.0674 | 0.0531 | 0.1418 | 0.1633 | 0.1596 | 0.1633 | 0.0887 | 0.0939 | 0.1348 | 0.1347 | 0.3617 | 0.3510 | 0.0030 | 0.0030 | 0.0119 | 0.0625 | 0.1310 | 0.1964 | 0.0923 | 0.1190 | 0.3810 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1130 | 460 | 653 | 578 | 83.3 | 9.22 | 65.56 | 101.38 | 71 | 74 | 78 | 80 | 83 | 86 | 89 | 92 | 95 | 0.3910 | 226 | 0.478 | 77.79 | 11.31 | 1 | 0.3155 | 206 | 0.1159 | 0.55 | 2.394 | 0.7678 | 7017.7 | 598559 | 51600000 | 4510000000 | 0.4222 | 0.2132 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0065 | 0.0015 | 0.0455 | 0.0352 | 0.0698 | 0.0674 | 0.0779 | 0.0260 | 0.1347 | 0.0475 | 0.6623 | 0.8224 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0047 | 0.0015 | 0.0376 | 0.0352 | 0.0610 | 0.0674 | 0.0297 | 0.0260 | 0.0563 | 0.0475 | 0.8075 | 0.8224 | 0.1304 | 0.0000 | 0.3478 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0435 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0151 | 0.0211 | 0.0452 | 0.0994 | 0.0964 | 0.1325 | 0.1687 | 0.4187 | 7 | 10 | 13 | 18 | 24 | 35 | 52 | 90 | 200 | 0.0809 | 31.27 | 3.431 | 0.5091 | 14559.2 | 5410000 | 2520000000 | 1320000000000 | 0.5610 | 0.0846 | 0.2727 | 0.0094 | 0.5000 | 0.0377 | 0.2273 | 0.4151 | 0.0000 | 0.3396 | 0.0000 | 0.1038 | 0.0000 | 0.0849 | 0.0000 | 0.0094 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0405 | 0.0091 | 0.0173 | 0.0274 | 0.0347 | 0.0365 | 0.2023 | 0.1507 | 0.3410 | 0.3196 | 0.1676 | 0.1553 | 0.1850 | 0.1918 | 0.0116 | 0.1050 | 0.0155 | 0.0177 | 0.0233 | 0.0265 | 0.0698 | 0.0885 | 0.0853 | 0.0619 | 0.2636 | 0.3894 | 0.3488 | 0.3009 | 0.1860 | 0.1150 | 0.0078 | 0.0000 | 0.0000 | 0.0000 | 0.0134 | 0.0201 | 0.0336 | 0.0336 | 0.2282 | 0.3758 | 0.2013 | 0.0940 | 0.0000 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 297 | 552 | 14385 | 28437 | 82.4 | 25.65 | 78.88 | 67.92 | 54 | 61 | 67 | 72 | 78 | 84 | 92 | 102 | 118 | 0.0619 | 1760 | 0.262 | 166.21 | 32.56 | 3 | 0.0482 | 693 | 0.0019 | 19.35 | 6.626 | 0.2629 | 7444.0 | 736986 | 79600000 | 9310000000 | 0.4815 | 0.1870 | 0.0021 | 0.0003 | 0.0065 | 0.0003 | 0.0131 | 0.0021 | 0.0495 | 0.0068 | 0.1160 | 0.0333 | 0.1694 | 0.0768 | 0.1624 | 0.0699 | 0.1801 | 0.1101 | 0.3009 | 0.7002 | 0.0009 | 0.0001 | 0.0024 | 0.0002 | 0.0052 | 0.0010 | 0.0160 | 0.0027 | 0.0436 | 0.0170 | 0.0742 | 0.0391 | 0.0712 | 0.0313 | 0.0969 | 0.0550 | 0.6896 | 0.8537 | 0.0030 | 0.0071 | 0.0075 | 0.0071 | 0.0157 | 0.0308 | 0.0392 | 0.0711 | 0.1000 | 0.1257 | 0.1440 | 0.1814 | 0.1217 | 0.1209 | 0.1491 | 0.1375 | 0.4199 | 0.3183 | 0.0030 | 0.0033 | 0.0113 | 0.0296 | 0.0612 | 0.1057 | 0.0936 | 0.1170 | 0.5753 | 13 | 21 | 32 | 44 | 58 | 75 | 98 | 130 | 177 | 0.0288 | 3.28 | 4.562 | 0.5810 | 10835.9 | 2010000 | 449000000 | 114000000000 | 0.4815 | 0.2042 | 0.0179 | 0.0044 | 0.0831 | 0.0084 | 0.1602 | 0.0296 | 0.1876 | 0.0792 | 0.1946 | 0.1523 | 0.1540 | 0.1942 | 0.1033 | 0.1555 | 0.0667 | 0.1609 | 0.0325 | 0.2154 | 0.0015 | 0.0018 | 0.0051 | 0.0029 | 0.0095 | 0.0074 | 0.0231 | 0.0180 | 0.0558 | 0.0481 | 0.0860 | 0.0817 | 0.0704 | 0.0668 | 0.0931 | 0.0878 | 0.6555 | 0.6854 | 0.0035 | 0.0026 | 0.0057 | 0.0037 | 0.0118 | 0.0131 | 0.0292 | 0.0330 | 0.0623 | 0.0748 | 0.1026 | 0.1123 | 0.0901 | 0.1017 | 0.1112 | 0.1253 | 0.5837 | 0.5335 | 0.0017 | 0.0054 | 0.0113 | 0.0279 | 0.0579 | 0.0968 | 0.0744 | 0.1004 | 0.6242 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 118 | 70 | 1754 | 4174 | 82.7 | 19.21 | 183.51 | 192.01 | 60 | 66 | 71 | 76 | 81 | 86 | 92 | 98 | 108 | 0.1445 | 603 | 0.362 | 172.26 | 45.00 | 1 | 0.4025 | 706 | 0.0023 | 27.82 | 6.291 | 0.2092 | 7207.4 | 660678 | 63600000 | 6400000000 | 0.4497 | 0.1988 | 0.0009 | 0.0000 | 0.0066 | 0.0000 | 0.0161 | 0.0031 | 0.0530 | 0.0093 | 0.1258 | 0.0322 | 0.1542 | 0.0811 | 0.1987 | 0.0619 | 0.2271 | 0.1002 | 0.2176 | 0.7123 | 0.0000 | 0.0000 | 0.0036 | 0.0000 | 0.0065 | 0.0017 | 0.0210 | 0.0035 | 0.0564 | 0.0239 | 0.0694 | 0.0554 | 0.0845 | 0.0309 | 0.1185 | 0.0612 | 0.6402 | 0.8233 | 0.0183 | 0.0101 | 0.0367 | 0.0202 | 0.0765 | 0.0808 | 0.1009 | 0.2121 | 0.1407 | 0.2323 | 0.1529 | 0.2222 | 0.1315 | 0.0909 | 0.1070 | 0.0909 | 0.2355 | 0.0404 | 0.0024 | 0.0120 | 0.0240 | 0.0456 | 0.0948 | 0.1116 | 0.1273 | 0.1645 | 0.4178 | 24 | 30 | 42 | 62 | 105 | 161 | 244 | 333 | 444 | 0.0173 | 43.47 | 5.837 | 0.3746 | 70533.6 | 37800000 | 24900000000 | 19100000000000 | 0.4742 | 0.1698 | 0.1259 | 0.0058 | 0.2370 | 0.0559 | 0.2840 | 0.2328 | 0.1457 | 0.1420 | 0.0889 | 0.1700 | 0.0617 | 0.1455 | 0.0420 | 0.0873 | 0.0099 | 0.0733 | 0.0049 | 0.0873 | 0.0011 | 0.0010 | 0.0028 | 0.0020 | 0.0091 | 0.0024 | 0.0300 | 0.0215 | 0.0935 | 0.0842 | 0.1230 | 0.1214 | 0.0941 | 0.0773 | 0.1423 | 0.1214 | 0.5040 | 0.5688 | 0.0007 | 0.0000 | 0.0059 | 0.0051 | 0.0074 | 0.0144 | 0.0368 | 0.0405 | 0.1177 | 0.1267 | 0.1575 | 0.1976 | 0.1302 | 0.1351 | 0.1707 | 0.1520 | 0.3731 | 0.3285 | 0.0013 | 0.0026 | 0.0059 | 0.0300 | 0.1019 | 0.1457 | 0.1130 | 0.1470 | 0.4526 | |
SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 902 | 486 | 1571 | 8752 | 79.8 | 18.38 | 25.85 | 63.61 | 59 | 62 | 66 | 70 | 75 | 84 | 92 | 99 | 106 | 0.0978 | 856 | 0.759 | 104.01 | 24.21 | 3 | 0.1827 | 287 | 0.0137 | 2.82 | 4.627 | 0.5218 | 6709.4 | 592170 | 54600000 | 5230000000 | 0.4037 | 0.2309 | 0.0050 | 0.0000 | 0.0099 | 0.0000 | 0.0236 | 0.0000 | 0.0459 | 0.0067 | 0.0980 | 0.0299 | 0.1613 | 0.0552 | 0.1365 | 0.0579 | 0.1675 | 0.0685 | 0.3524 | 0.7818 | 0.0033 | 0.0000 | 0.0033 | 0.0000 | 0.0117 | 0.0000 | 0.0208 | 0.0045 | 0.0400 | 0.0248 | 0.0650 | 0.0446 | 0.0550 | 0.0299 | 0.0708 | 0.0350 | 0.7300 | 0.8611 | 0.0000 | 0.0299 | 0.0000 | 0.0746 | 0.0203 | 0.0597 | 0.0330 | 0.1642 | 0.0787 | 0.1045 | 0.1320 | 0.1493 | 0.1142 | 0.0746 | 0.1345 | 0.1194 | 0.4873 | 0.2239 | 0.0000 | 0.0057 | 0.0057 | 0.0213 | 0.0355 | 0.0682 | 0.0540 | 0.0753 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 12 | 53 | 0.2949 | 7.14 | 2.200 | 0.6924 | 4714.0 | 1480000 | 590000000 | 281000000000 | 0.4076 | 0.1755 | 0.0603 | 0.0111 | 0.2915 | 0.0379 | 0.4824 | 0.1737 | 0.1407 | 0.2517 | 0.0101 | 0.2539 | 0.0101 | 0.1403 | 0.0050 | 0.0802 | 0.0000 | 0.0379 | 0.0000 | 0.0134 | 0.0008 | 0.0035 | 0.0041 | 0.0077 | 0.0154 | 0.0153 | 0.0170 | 0.0251 | 0.0519 | 0.0537 | 0.0787 | 0.0760 | 0.0463 | 0.0530 | 0.0779 | 0.0746 | 0.7078 | 0.6911 | 0.0019 | 0.0030 | 0.0039 | 0.0020 | 0.0048 | 0.0030 | 0.0087 | 0.0071 | 0.0571 | 0.0569 | 0.0871 | 0.0944 | 0.0600 | 0.0650 | 0.0794 | 0.0792 | 0.6970 | 0.6893 | 0.0018 | 0.0090 | 0.0045 | 0.0170 | 0.0502 | 0.0806 | 0.0556 | 0.0762 | 0.7052 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 438 | 881 | 789 | 8063 | 74.1 | 31.85 | 47.97 | 131.71 | 30 | 40 | 55 | 65 | 73 | 81 | 92 | 101 | 116 | 0.0633 | 510 | 0.386 | 127.58 | 22.47 | 2 | 0.5982 | 472 | 0.0024 | 38.72 | 6.180 | 0.1858 | 6504.0 | 641928 | 68900000 | 7880000000 | 0.3632 | 0.2507 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0538 | 0.0043 | 0.1000 | 0.0172 | 0.2115 | 0.0948 | 0.1808 | 0.1401 | 0.1846 | 0.1185 | 0.1692 | 0.1789 | 0.0962 | 0.4461 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0135 | 0.0049 | 0.0558 | 0.0395 | 0.0673 | 0.0543 | 0.0635 | 0.0329 | 0.0885 | 0.0625 | 0.7115 | 0.8059 | 0.0000 | 0.0000 | 0.0154 | 0.0139 | 0.0077 | 0.0625 | 0.0346 | 0.0694 | 0.0962 | 0.1319 | 0.1269 | 0.1667 | 0.1038 | 0.1528 | 0.1692 | 0.1250 | 0.4462 | 0.2778 | 0.0026 | 0.0000 | 0.0026 | 0.0179 | 0.0742 | 0.0818 | 0.1023 | 0.1560 | 0.5627 | 11 | 13 | 15 | 16 | 18 | 20 | 22 | 26 | 61 | 0.4823 | 4.88 | 1.769 | 0.8585 | 19647.5 | 17700000 | 20000000000 | 25500000000000 | 0.6771 | 0.1020 | 0.0533 | 0.0311 | 0.1557 | 0.0251 | 0.2172 | 0.0621 | 0.2377 | 0.0932 | 0.2008 | 0.1657 | 0.0820 | 0.2027 | 0.0287 | 0.1686 | 0.0164 | 0.1198 | 0.0082 | 0.1317 | 0.0000 | 0.0147 | 0.0009 | 0.0077 | 0.0046 | 0.0105 | 0.0352 | 0.0252 | 0.0897 | 0.0617 | 0.1175 | 0.0870 | 0.1027 | 0.1024 | 0.1036 | 0.1080 | 0.5458 | 0.5827 | 0.0012 | 0.0013 | 0.0036 | 0.0027 | 0.0060 | 0.0080 | 0.0239 | 0.0213 | 0.1004 | 0.1120 | 0.1470 | 0.1600 | 0.1016 | 0.0973 | 0.1147 | 0.1307 | 0.5018 | 0.4667 | 0.0000 | 0.0011 | 0.0074 | 0.0253 | 0.1077 | 0.1267 | 0.0940 | 0.1109 | 0.5269 |