High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 838 | 827 | | 348 | 3785 | 69.6 | 9.59 | 7.19 | 2.56 | 58 | 61 | 63 | 66 | 69 | 71 | 74 | 78 | 83 | 0.1007 | 381 | 1.208 | 26.48 | 9.85 | 4 | 0.2011 | 70 | 0.0757 | 0.82 | 2.819 | 0.6940 | 4931.9 | 356260 | 26200000 | 1970000000 | 0.3634 | 0.2597 | 0.0033 | 0.0000 | 0.0100 | 0.0000 | 0.0133 | 0.0029 | 0.0332 | 0.0144 | 0.0698 | 0.0720 | 0.0997 | 0.0778 | 0.1096 | 0.0692 | 0.2359 | 0.1268 | 0.4252 | 0.6369 | 0.0030 | 0.0000 | 0.0000 | 0.0000 | 0.0090 | 0.0029 | 0.0181 | 0.0144 | 0.0633 | 0.0690 | 0.0843 | 0.0776 | 0.0663 | 0.0690 | 0.1506 | 0.1149 | 0.6054 | 0.6523 | 0.0323 | 1.0000 | 0.0000 | 0.0000 | 0.1613 | 0.0000 | 0.2258 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.1935 | 0.0000 | 0.1290 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0062 | 0.0247 | 0.0988 | 0.1358 | 0.1420 | 0.1235 | 0.1728 | 0.2840 | 4 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 0.0188 | 7.92 | 4.396 | 0.3583 | 58.2 | 526.12 | 5258.33 | 57582.2 | 0.4841 | 0.1761 | 0.0222 | 0.0039 | 0.0672 | 0.0054 | 0.1627 | 0.0219 | 0.2267 | 0.0409 | 0.2391 | 0.0828 | 0.1725 | 0.1441 | 0.0826 | 0.2539 | 0.0246 | 0.3015 | 0.0025 | 0.1456 | 0.0046 | 0.0003 | 0.0185 | 0.0006 | 0.0490 | 0.0059 | 0.0817 | 0.0178 | 0.1214 | 0.0422 | 0.1762 | 0.0716 | 0.1689 | 0.1446 | 0.1823 | 0.2904 | 0.1974 | 0.4267 | 0.1226 | 0.1623 | 0.1493 | 0.1451 | 0.1143 | 0.1019 | 0.1184 | 0.1036 | 0.0917 | 0.0829 | 0.0937 | 0.0760 | 0.0814 | 0.0864 | 0.0937 | 0.1330 | 0.1349 | 0.1088 | 0.0153 | 0.0463 | 0.0769 | 0.1084 | 0.1441 | 0.1724 | 0.1585 | 0.1298 | 0.1483 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 279 | 429 | | 995 | 12586 | 70.7 | 14.90 | 155.58 | 186.93 | 55 | 59 | 63 | 66 | 69 | 72 | 76 | 81 | 90 | 0.0678 | 853 | 0.399 | 137.53 | 31.00 | 1 | 0.5668 | 564 | 0.0090 | 7.28 | 5.031 | 0.3913 | 5218.8 | 403150 | 32700000 | 2780000000 | 0.5290 | 0.1303 | 0.0014 | 0.0000 | 0.0041 | 0.0000 | 0.0218 | 0.0032 | 0.0476 | 0.0139 | 0.1252 | 0.0586 | 0.1823 | 0.1471 | 0.1469 | 0.0768 | 0.1524 | 0.1333 | 0.3184 | 0.5672 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0046 | 0.0020 | 0.0207 | 0.0061 | 0.0794 | 0.0499 | 0.1427 | 0.1314 | 0.0863 | 0.0540 | 0.1116 | 0.0967 | 0.5524 | 0.6599 | 0.0149 | 0.0455 | 0.0149 | 0.0000 | 0.0522 | 0.1136 | 0.1343 | 0.1136 | 0.2015 | 0.2955 | 0.2015 | 0.2045 | 0.1119 | 0.0227 | 0.1269 | 0.1818 | 0.1418 | 0.0227 | 0.0068 | 0.0158 | 0.0158 | 0.0813 | 0.1512 | 0.1558 | 0.1129 | 0.1490 | 0.3115 | 16 | 20 | 30 | 53 | 84 | 116 | 167 | 264 | 418 | 0.0235 | 46.09 | 5.759 | 0.4355 | 59144.7 | 33000000 | 22700000000 | 17700000000000 | 0.5490 | 0.1235 | 0.0353 | 0.0025 | 0.1470 | 0.0151 | 0.2292 | 0.0792 | 0.1425 | 0.1235 | 0.1447 | 0.1704 | 0.1190 | 0.1746 | 0.0816 | 0.1179 | 0.0654 | 0.1193 | 0.0353 | 0.1975 | 0.0004 | 0.0007 | 0.0004 | 0.0019 | 0.0042 | 0.0029 | 0.0129 | 0.0102 | 0.0601 | 0.0507 | 0.1106 | 0.0865 | 0.0811 | 0.0676 | 0.1162 | 0.1025 | 0.6141 | 0.6771 | 0.0009 | 0.0010 | 0.0023 | 0.0017 | 0.0032 | 0.0023 | 0.0227 | 0.0252 | 0.0827 | 0.1026 | 0.1474 | 0.1437 | 0.0903 | 0.1010 | 0.1282 | 0.1400 | 0.5223 | 0.4826 | 0.0002 | 0.0015 | 0.0037 | 0.0187 | 0.0791 | 0.1231 | 0.0843 | 0.1271 | 0.5622 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 309 | 735 | | 1819 | 14901 | 73.2 | 15.19 | 136.21 | 157.45 | 56 | 62 | 65 | 67 | 70 | 74 | 79 | 85 | 94 | 0.0571 | 851 | 0.961 | 66.85 | 20.22 | 3 | 0.0995 | 181 | 0.0042 | 13.83 | 5.799 | 0.2858 | 5584.7 | 444991 | 37000000 | 3220000000 | 0.5015 | 0.1554 | 0.0008 | 0.0000 | 0.0047 | 0.0006 | 0.0228 | 0.0012 | 0.0417 | 0.0140 | 0.1133 | 0.0450 | 0.1707 | 0.1040 | 0.1526 | 0.0900 | 0.1794 | 0.1244 | 0.3139 | 0.6209 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0069 | 0.0011 | 0.0202 | 0.0117 | 0.0656 | 0.0362 | 0.1040 | 0.0841 | 0.0807 | 0.0523 | 0.1230 | 0.0885 | 0.5984 | 0.7255 | 0.0095 | 0.0238 | 0.0063 | 0.0357 | 0.0381 | 0.1190 | 0.1175 | 0.2381 | 0.1460 | 0.1905 | 0.2190 | 0.1429 | 0.1238 | 0.0833 | 0.1143 | 0.0833 | 0.2254 | 0.0833 | 0.0025 | 0.0135 | 0.0197 | 0.0492 | 0.1095 | 0.1365 | 0.1267 | 0.1501 | 0.3924 | 14 | 17 | 23 | 40 | 73 | 110 | 160 | 243 | 367 | 0.0319 | 18.03 | 5.311 | 0.4923 | 43340.4 | 19300000 | 10300000000 | 6180000000000 | 0.4512 | 0.1992 | 0.0348 | 0.0006 | 0.1211 | 0.0135 | 0.2124 | 0.0737 | 0.1696 | 0.0995 | 0.1621 | 0.1575 | 0.1286 | 0.1894 | 0.0776 | 0.1317 | 0.0547 | 0.1357 | 0.0391 | 0.1983 | 0.0008 | 0.0000 | 0.0012 | 0.0006 | 0.0050 | 0.0021 | 0.0163 | 0.0107 | 0.0553 | 0.0478 | 0.0947 | 0.0811 | 0.0696 | 0.0552 | 0.0962 | 0.0929 | 0.6610 | 0.7096 | 0.0009 | 0.0008 | 0.0018 | 0.0024 | 0.0075 | 0.0050 | 0.0218 | 0.0214 | 0.0693 | 0.0833 | 0.1160 | 0.1303 | 0.0869 | 0.0844 | 0.1141 | 0.1295 | 0.5816 | 0.5430 | 0.0008 | 0.0010 | 0.0031 | 0.0189 | 0.0617 | 0.1060 | 0.0742 | 0.1094 | 0.6249 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 202 | 300 | | 6785 | 14162 | 73.6 | 17.99 | 128.75 | 204.22 | 55 | 60 | 64 | 67 | 70 | 74 | 78 | 85 | 98 | 0.0703 | 996 | 0.964 | 72.80 | 24.35 | 1 | 0.0280 | 190 | 0.0034 | 16.24 | 6.105 | 0.2850 | 5739.9 | 477688 | 42700000 | 4120000000 | 0.4408 | 0.2110 | 0.0005 | 0.0000 | 0.0039 | 0.0005 | 0.0122 | 0.0021 | 0.0270 | 0.0047 | 0.0766 | 0.0226 | 0.1354 | 0.0389 | 0.1541 | 0.0501 | 0.2125 | 0.0784 | 0.3779 | 0.8028 | 0.0002 | 0.0000 | 0.0015 | 0.0001 | 0.0044 | 0.0000 | 0.0115 | 0.0003 | 0.0412 | 0.0127 | 0.0738 | 0.0228 | 0.0842 | 0.0195 | 0.1337 | 0.0408 | 0.6495 | 0.9038 | 0.0089 | 0.0082 | 0.0124 | 0.0392 | 0.0231 | 0.0351 | 0.0738 | 0.1072 | 0.1120 | 0.1691 | 0.1431 | 0.1794 | 0.1182 | 0.1381 | 0.1476 | 0.1196 | 0.3609 | 0.2041 | 0.0051 | 0.0116 | 0.0260 | 0.0619 | 0.0952 | 0.1284 | 0.1208 | 0.1302 | 0.4208 | 12 | 14 | 16 | 19 | 29 | 64 | 131 | 219 | 365 | 0.0796 | 32.45 | 4.690 | 0.5502 | 58277.5 | 46900000 | 56200000000 | 88300000000000 | 0.5837 | 0.1324 | 0.0408 | 0.0021 | 0.1841 | 0.0191 | 0.2326 | 0.0908 | 0.1830 | 0.1300 | 0.1709 | 0.1990 | 0.1158 | 0.1879 | 0.0364 | 0.1423 | 0.0254 | 0.1147 | 0.0110 | 0.1141 | 0.0008 | 0.0004 | 0.0008 | 0.0017 | 0.0017 | 0.0017 | 0.0080 | 0.0075 | 0.0431 | 0.0368 | 0.0772 | 0.0632 | 0.0574 | 0.0462 | 0.1056 | 0.0896 | 0.7054 | 0.7529 | 0.0008 | 0.0006 | 0.0008 | 0.0020 | 0.0029 | 0.0050 | 0.0130 | 0.0190 | 0.0619 | 0.0781 | 0.1060 | 0.1085 | 0.0824 | 0.0930 | 0.1331 | 0.1355 | 0.5993 | 0.5582 | 0.0000 | 0.0009 | 0.0016 | 0.0108 | 0.0498 | 0.0912 | 0.0683 | 0.1170 | 0.6604 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 870 | 152 | | 2506 | 5703 | 72.8 | 23.73 | 226.65 | 206.12 | 44 | 52 | 59 | 65 | 71 | 77 | 83 | 92 | 106 | 0.1012 | 577 | 0.226 | 301.04 | 33.94 | 3 | 0.4254 | 1066 | 0.0017 | 34.53 | 6.624 | 0.1875 | 5856.8 | 514772 | 48800000 | 4950000000 | 0.4100 | 0.2367 | 0.0000 | 0.0000 | 0.0094 | 0.0000 | 0.0309 | 0.0015 | 0.0738 | 0.0082 | 0.1639 | 0.0494 | 0.1966 | 0.0937 | 0.1949 | 0.1105 | 0.1768 | 0.1549 | 0.1536 | 0.5818 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0009 | 0.0147 | 0.0035 | 0.0548 | 0.0288 | 0.0892 | 0.0399 | 0.0926 | 0.0465 | 0.1242 | 0.0798 | 0.6222 | 0.8005 | 0.0050 | 0.0068 | 0.0149 | 0.0068 | 0.0215 | 0.0375 | 0.0809 | 0.1024 | 0.1601 | 0.2321 | 0.1700 | 0.1945 | 0.1221 | 0.1229 | 0.1535 | 0.1468 | 0.2723 | 0.1502 | 0.0017 | 0.0025 | 0.0142 | 0.0418 | 0.0879 | 0.1431 | 0.1305 | 0.1423 | 0.4360 | 33 | 48 | 74 | 110 | 160 | 220 | 294 | 390 | 525 | 0.0110 | 30.01 | 5.917 | 0.3620 | 93846.7 | 52100000 | 34500000000 | 25800000000000 | 0.5031 | 0.1657 | 0.0592 | 0.0019 | 0.2513 | 0.0205 | 0.2592 | 0.1189 | 0.1526 | 0.1841 | 0.1079 | 0.1937 | 0.0921 | 0.1688 | 0.0434 | 0.1119 | 0.0224 | 0.0985 | 0.0118 | 0.1017 | 0.0000 | 0.0000 | 0.0023 | 0.0013 | 0.0080 | 0.0035 | 0.0221 | 0.0190 | 0.0865 | 0.0723 | 0.1319 | 0.1138 | 0.1021 | 0.0826 | 0.1444 | 0.1157 | 0.5027 | 0.5919 | 0.0011 | 0.0026 | 0.0038 | 0.0026 | 0.0145 | 0.0168 | 0.0376 | 0.0510 | 0.1175 | 0.1395 | 0.1760 | 0.1802 | 0.1180 | 0.1298 | 0.1352 | 0.1486 | 0.3965 | 0.3288 | 0.0009 | 0.0018 | 0.0086 | 0.0378 | 0.0991 | 0.1535 | 0.1153 | 0.1346 | 0.4484 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1017 | 554 | | 378 | 9755 | 70.8 | 9.18 | 6.27 | 2.35 | 58 | 62 | 65 | 69 | 72 | 74 | 76 | 79 | 82 | 0.0685 | 668 | 1.025 | 80.23 | 26.63 | 2 | 0.5556 | 210 | 0.0307 | 2.20 | 3.799 | 0.5317 | 5100.6 | 373029 | 27700000 | 2080000000 | 0.3766 | 0.2528 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0121 | 0.0053 | 0.0725 | 0.0556 | 0.0816 | 0.0635 | 0.0816 | 0.0503 | 0.1178 | 0.0688 | 0.6284 | 0.7566 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0116 | 0.0053 | 0.0607 | 0.0556 | 0.0665 | 0.0635 | 0.0520 | 0.0503 | 0.0838 | 0.0688 | 0.7197 | 0.7566 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.0000 | 0.0000 | 0.1333 | 0.0000 | 0.0000 | 0.0093 | 0.0139 | 0.0324 | 0.0694 | 0.0787 | 0.0972 | 0.1481 | 0.5509 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.2315 | 0.45 | 1.048 | 0.5873 | 44.8 | 356.698 | 3133.82 | 30121.9 | 0.5230 | 0.1563 | 0.0095 | 0.0016 | 0.0423 | 0.0054 | 0.1159 | 0.0156 | 0.1913 | 0.0399 | 0.2491 | 0.0756 | 0.2068 | 0.1496 | 0.1260 | 0.2580 | 0.0507 | 0.3008 | 0.0085 | 0.1535 | 0.0009 | 0.0000 | 0.0033 | 0.0003 | 0.0157 | 0.0022 | 0.0417 | 0.0102 | 0.0896 | 0.0267 | 0.1561 | 0.0434 | 0.2071 | 0.1072 | 0.2316 | 0.2692 | 0.2540 | 0.5409 | 0.0990 | 0.1881 | 0.1831 | 0.2085 | 0.1795 | 0.1599 | 0.1502 | 0.1178 | 0.1272 | 0.0944 | 0.0980 | 0.0655 | 0.0618 | 0.0505 | 0.0512 | 0.0589 | 0.0501 | 0.0565 | 0.0080 | 0.0313 | 0.0735 | 0.1349 | 0.1725 | 0.1695 | 0.1459 | 0.1396 | 0.1248 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 944 | 643 | | 10766 | 25398 | 77.7 | 26.50 | 79.35 | 104.73 | 50 | 58 | 63 | 68 | 73 | 79 | 85 | 93 | 108 | 0.0568 | 1442 | 1.039 | 62.30 | 19.70 | 12 | 0.0144 | 155 | 0.0021 | 19.33 | 6.548 | 0.2687 | 6739.6 | 660302 | 73500000 | 9260000000 | 0.4514 | 0.1914 | 0.0004 | 0.0001 | 0.0041 | 0.0004 | 0.0155 | 0.0014 | 0.0404 | 0.0069 | 0.0933 | 0.0282 | 0.1426 | 0.0518 | 0.1465 | 0.0640 | 0.1811 | 0.0814 | 0.3762 | 0.7657 | 0.0003 | 0.0000 | 0.0017 | 0.0001 | 0.0045 | 0.0006 | 0.0160 | 0.0048 | 0.0422 | 0.0180 | 0.0703 | 0.0309 | 0.0638 | 0.0353 | 0.1024 | 0.0473 | 0.6987 | 0.8630 | 0.0039 | 0.0067 | 0.0111 | 0.0183 | 0.0261 | 0.0202 | 0.0623 | 0.0577 | 0.1044 | 0.0876 | 0.1358 | 0.1107 | 0.0894 | 0.0808 | 0.1049 | 0.1078 | 0.4621 | 0.5101 | 0.0018 | 0.0078 | 0.0155 | 0.0331 | 0.0750 | 0.0992 | 0.0965 | 0.1223 | 0.5488 | 24 | 27 | 31 | 34 | 39 | 47 | 64 | 99 | 187 | 0.1253 | 4.89 | 3.514 | 0.7026 | 17262.9 | 7360000 | 4380000000 | 3170000000000 | 0.5875 | 0.1331 | 0.0281 | 0.0053 | 0.1260 | 0.0156 | 0.1868 | 0.0425 | 0.1366 | 0.0966 | 0.1545 | 0.1560 | 0.1417 | 0.1683 | 0.1034 | 0.1305 | 0.0757 | 0.1316 | 0.0472 | 0.2536 | 0.0005 | 0.0026 | 0.0029 | 0.0056 | 0.0074 | 0.0082 | 0.0218 | 0.0211 | 0.0702 | 0.0565 | 0.0928 | 0.0744 | 0.0750 | 0.0686 | 0.1091 | 0.0987 | 0.6202 | 0.6644 | 0.0015 | 0.0009 | 0.0017 | 0.0024 | 0.0077 | 0.0079 | 0.0283 | 0.0323 | 0.0924 | 0.0996 | 0.1194 | 0.1287 | 0.0811 | 0.0910 | 0.1267 | 0.1337 | 0.5411 | 0.5034 | 0.0002 | 0.0021 | 0.0070 | 0.0280 | 0.0826 | 0.1089 | 0.0754 | 0.1199 | 0.5761 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 438 | 881 | | 789 | 8063 | 74.1 | 31.85 | 47.97 | 131.71 | 30 | 40 | 55 | 65 | 73 | 81 | 92 | 101 | 116 | 0.0633 | 510 | 0.386 | 127.58 | 22.47 | 2 | 0.5982 | 472 | 0.0024 | 38.72 | 6.180 | 0.1858 | 6504.0 | 641928 | 68900000 | 7880000000 | 0.3632 | 0.2507 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0538 | 0.0043 | 0.1000 | 0.0172 | 0.2115 | 0.0948 | 0.1808 | 0.1401 | 0.1846 | 0.1185 | 0.1692 | 0.1789 | 0.0962 | 0.4461 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0135 | 0.0049 | 0.0558 | 0.0395 | 0.0673 | 0.0543 | 0.0635 | 0.0329 | 0.0885 | 0.0625 | 0.7115 | 0.8059 | 0.0000 | 0.0000 | 0.0154 | 0.0139 | 0.0077 | 0.0625 | 0.0346 | 0.0694 | 0.0962 | 0.1319 | 0.1269 | 0.1667 | 0.1038 | 0.1528 | 0.1692 | 0.1250 | 0.4462 | 0.2778 | 0.0026 | 0.0000 | 0.0026 | 0.0179 | 0.0742 | 0.0818 | 0.1023 | 0.1560 | 0.5627 | 11 | 13 | 15 | 16 | 18 | 20 | 22 | 26 | 61 | 0.4823 | 4.88 | 1.769 | 0.8585 | 19647.5 | 17700000 | 20000000000 | 25500000000000 | 0.6771 | 0.1020 | 0.0533 | 0.0311 | 0.1557 | 0.0251 | 0.2172 | 0.0621 | 0.2377 | 0.0932 | 0.2008 | 0.1657 | 0.0820 | 0.2027 | 0.0287 | 0.1686 | 0.0164 | 0.1198 | 0.0082 | 0.1317 | 0.0000 | 0.0147 | 0.0009 | 0.0077 | 0.0046 | 0.0105 | 0.0352 | 0.0252 | 0.0897 | 0.0617 | 0.1175 | 0.0870 | 0.1027 | 0.1024 | 0.1036 | 0.1080 | 0.5458 | 0.5827 | 0.0012 | 0.0013 | 0.0036 | 0.0027 | 0.0060 | 0.0080 | 0.0239 | 0.0213 | 0.1004 | 0.1120 | 0.1470 | 0.1600 | 0.1016 | 0.0973 | 0.1147 | 0.1307 | 0.5018 | 0.4667 | 0.0000 | 0.0011 | 0.0074 | 0.0253 | 0.1077 | 0.1267 | 0.0940 | 0.1109 | 0.5269 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 274 | 223 | | 6457 | 17021 | 77.3 | 19.26 | 210.94 | 213.95 | 57 | 61 | 66 | 70 | 74 | 78 | 84 | 91 | 103 | 0.0644 | 1096 | 0.843 | 90.43 | 26.17 | 1 | 0.0367 | 237 | 0.0028 | 17.12 | 6.228 | 0.2745 | 6348.3 | 556064 | 52200000 | 5250000000 | 0.4510 | 0.1996 | 0.0010 | 0.0000 | 0.0056 | 0.0003 | 0.0133 | 0.0005 | 0.0380 | 0.0061 | 0.0745 | 0.0225 | 0.1425 | 0.0484 | 0.1711 | 0.0522 | 0.2152 | 0.0849 | 0.3389 | 0.7851 | 0.0004 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0000 | 0.0163 | 0.0020 | 0.0342 | 0.0138 | 0.0671 | 0.0273 | 0.0778 | 0.0218 | 0.1102 | 0.0414 | 0.6848 | 0.8935 | 0.0074 | 0.0130 | 0.0197 | 0.0216 | 0.0303 | 0.0670 | 0.0663 | 0.1058 | 0.1286 | 0.1685 | 0.1335 | 0.1598 | 0.1179 | 0.1102 | 0.1605 | 0.1102 | 0.3358 | 0.2441 | 0.0024 | 0.0094 | 0.0171 | 0.0447 | 0.0765 | 0.1024 | 0.1080 | 0.1279 | 0.5114 | 18 | 30 | 63 | 104 | 145 | 194 | 257 | 356 | 511 | 0.0108 | 28.47 | 6.188 | 0.3938 | 90266.1 | 55800000 | 45300000000 | 46700000000000 | 0.5019 | 0.1685 | 0.0158 | 0.0008 | 0.0801 | 0.0060 | 0.1780 | 0.0286 | 0.1711 | 0.0730 | 0.1885 | 0.1548 | 0.1561 | 0.2064 | 0.0991 | 0.1523 | 0.0752 | 0.1528 | 0.0360 | 0.2253 | 0.0009 | 0.0001 | 0.0013 | 0.0006 | 0.0042 | 0.0030 | 0.0144 | 0.0093 | 0.0568 | 0.0438 | 0.0954 | 0.0772 | 0.0796 | 0.0684 | 0.1057 | 0.0967 | 0.6416 | 0.7008 | 0.0013 | 0.0018 | 0.0031 | 0.0027 | 0.0098 | 0.0098 | 0.0233 | 0.0219 | 0.0729 | 0.0825 | 0.1141 | 0.1324 | 0.0873 | 0.0882 | 0.1187 | 0.1185 | 0.5694 | 0.5421 | 0.0022 | 0.0021 | 0.0062 | 0.0230 | 0.0643 | 0.1045 | 0.0826 | 0.1072 | 0.6079 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 124 | | 725 | 2122 | 76.0 | 19.18 | 87.85 | 150.35 | 55 | 62 | 66 | 70 | 74 | 78 | 82 | 89 | 98 | 0.1555 | 330 | 1.062 | 83.67 | 27.73 | 1 | 0.3007 | 218 | 0.0059 | 12.27 | 5.382 | 0.3021 | 6143.7 | 529049 | 48700000 | 4800000000 | 0.4598 | 0.1774 | 0.0021 | 0.0000 | 0.0105 | 0.0000 | 0.0316 | 0.0062 | 0.0547 | 0.0170 | 0.1116 | 0.0602 | 0.1495 | 0.0802 | 0.1558 | 0.0725 | 0.1811 | 0.1065 | 0.3032 | 0.6574 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0100 | 0.0014 | 0.0067 | 0.0029 | 0.0585 | 0.0432 | 0.1137 | 0.0748 | 0.0870 | 0.0489 | 0.1421 | 0.0691 | 0.5803 | 0.7597 | 0.0081 | 0.0213 | 0.0488 | 0.0000 | 0.0407 | 0.0638 | 0.0894 | 0.1489 | 0.2602 | 0.2340 | 0.1057 | 0.2340 | 0.1545 | 0.0638 | 0.1463 | 0.0851 | 0.1463 | 0.1489 | 0.0000 | 0.0030 | 0.0302 | 0.0604 | 0.1329 | 0.1813 | 0.1390 | 0.1601 | 0.2931 | 14 | 17 | 20 | 25 | 38 | 53 | 73 | 106 | 191 | 0.0472 | 42.92 | 4.329 | 0.5495 | 30310.8 | 21700000 | 20800000000 | 23000000000000 | 0.5356 | 0.1304 | 0.0400 | 0.0000 | 0.1778 | 0.0200 | 0.1689 | 0.0798 | 0.2267 | 0.1098 | 0.1289 | 0.1377 | 0.1333 | 0.1896 | 0.0978 | 0.1337 | 0.0178 | 0.1018 | 0.0089 | 0.2275 | 0.0015 | 0.0000 | 0.0122 | 0.0000 | 0.0198 | 0.0141 | 0.0517 | 0.0387 | 0.0836 | 0.0810 | 0.1049 | 0.1244 | 0.1094 | 0.0845 | 0.1261 | 0.1315 | 0.4909 | 0.5258 | 0.0000 | 0.0028 | 0.0139 | 0.0057 | 0.0254 | 0.0256 | 0.0647 | 0.0427 | 0.1062 | 0.1225 | 0.1201 | 0.1595 | 0.1178 | 0.0798 | 0.1293 | 0.1681 | 0.4226 | 0.3932 | 0.0019 | 0.0130 | 0.0093 | 0.0484 | 0.1043 | 0.1229 | 0.0987 | 0.1378 | 0.4637 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 735 | 406 | | 428 | 1601 | 77.0 | 10.85 | 11.27 | 14.00 | 65 | 67 | 70 | 72 | 75 | 77 | 82 | 86 | 93 | 0.1643 | 263 | 0.708 | 113.88 | 25.02 | 1 | 0.6636 | 284 | 0.0441 | 1.02 | 3.411 | 0.6516 | 6040.7 | 483894 | 39600000 | 3310000000 | 0.3996 | 0.2382 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0053 | 0.0024 | 0.0718 | 0.0447 | 0.1011 | 0.0753 | 0.0638 | 0.0400 | 0.1277 | 0.0918 | 0.6303 | 0.7435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0047 | 0.0023 | 0.0498 | 0.0444 | 0.0687 | 0.0724 | 0.0332 | 0.0304 | 0.0782 | 0.0748 | 0.7654 | 0.7734 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 1.0000 | 0.0217 | 0.0000 | 0.1739 | 0.0000 | 0.1304 | 0.0000 | 0.1304 | 0.0000 | 0.1522 | 0.0000 | 0.3478 | 0.0000 | 0.0053 | 0.0000 | 0.0105 | 0.0474 | 0.0579 | 0.1000 | 0.0947 | 0.1263 | 0.5579 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 12 | 15 | 0.6009 | 2.10 | 1.178 | 0.8849 | 322.9 | 27681.3 | 3820000 | 619000000 | 0.6572 | 0.0788 | 0.0682 | 0.0020 | 0.1326 | 0.0188 | 0.1111 | 0.0683 | 0.1189 | 0.0960 | 0.1598 | 0.1317 | 0.1774 | 0.1545 | 0.1365 | 0.1535 | 0.0741 | 0.1723 | 0.0214 | 0.2030 | 0.0477 | 0.0017 | 0.0846 | 0.0145 | 0.0682 | 0.0513 | 0.0628 | 0.0803 | 0.1010 | 0.1103 | 0.1173 | 0.1350 | 0.1119 | 0.1325 | 0.1364 | 0.1556 | 0.2701 | 0.3188 | 0.0591 | 0.0313 | 0.0727 | 0.0313 | 0.0364 | 0.0313 | 0.0591 | 0.0625 | 0.0773 | 0.1188 | 0.1545 | 0.1688 | 0.1364 | 0.1813 | 0.1909 | 0.2125 | 0.2136 | 0.1625 | 0.0592 | 0.0547 | 0.0661 | 0.0957 | 0.1207 | 0.1276 | 0.1116 | 0.1344 | 0.2301 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 902 | 486 | | 1571 | 8752 | 79.8 | 18.38 | 25.85 | 63.61 | 59 | 62 | 66 | 70 | 75 | 84 | 92 | 99 | 106 | 0.0978 | 856 | 0.759 | 104.01 | 24.21 | 3 | 0.1827 | 287 | 0.0137 | 2.82 | 4.627 | 0.5218 | 6709.4 | 592170 | 54600000 | 5230000000 | 0.4037 | 0.2309 | 0.0050 | 0.0000 | 0.0099 | 0.0000 | 0.0236 | 0.0000 | 0.0459 | 0.0067 | 0.0980 | 0.0299 | 0.1613 | 0.0552 | 0.1365 | 0.0579 | 0.1675 | 0.0685 | 0.3524 | 0.7818 | 0.0033 | 0.0000 | 0.0033 | 0.0000 | 0.0117 | 0.0000 | 0.0208 | 0.0045 | 0.0400 | 0.0248 | 0.0650 | 0.0446 | 0.0550 | 0.0299 | 0.0708 | 0.0350 | 0.7300 | 0.8611 | 0.0000 | 0.0299 | 0.0000 | 0.0746 | 0.0203 | 0.0597 | 0.0330 | 0.1642 | 0.0787 | 0.1045 | 0.1320 | 0.1493 | 0.1142 | 0.0746 | 0.1345 | 0.1194 | 0.4873 | 0.2239 | 0.0000 | 0.0057 | 0.0057 | 0.0213 | 0.0355 | 0.0682 | 0.0540 | 0.0753 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 12 | 53 | 0.2949 | 7.14 | 2.200 | 0.6924 | 4714.0 | 1480000 | 590000000 | 281000000000 | 0.4076 | 0.1755 | 0.0603 | 0.0111 | 0.2915 | 0.0379 | 0.4824 | 0.1737 | 0.1407 | 0.2517 | 0.0101 | 0.2539 | 0.0101 | 0.1403 | 0.0050 | 0.0802 | 0.0000 | 0.0379 | 0.0000 | 0.0134 | 0.0008 | 0.0035 | 0.0041 | 0.0077 | 0.0154 | 0.0153 | 0.0170 | 0.0251 | 0.0519 | 0.0537 | 0.0787 | 0.0760 | 0.0463 | 0.0530 | 0.0779 | 0.0746 | 0.7078 | 0.6911 | 0.0019 | 0.0030 | 0.0039 | 0.0020 | 0.0048 | 0.0030 | 0.0087 | 0.0071 | 0.0571 | 0.0569 | 0.0871 | 0.0944 | 0.0600 | 0.0650 | 0.0794 | 0.0792 | 0.6970 | 0.6893 | 0.0018 | 0.0090 | 0.0045 | 0.0170 | 0.0502 | 0.0806 | 0.0556 | 0.0762 | 0.7052 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1270 | 935 | | 2332 | 2784 | 77.0 | 17.41 | 147.31 | 171.19 | 57 | 63 | 67 | 71 | 75 | 79 | 84 | 90 | 98 | 0.1566 | 436 | 0.850 | 77.94 | 29.70 | 1 | 0.1038 | 242 | 0.0063 | 9.67 | 5.383 | 0.3501 | 6226.1 | 531430 | 48100000 | 4640000000 | 0.4627 | 0.1874 | 0.0013 | 0.0000 | 0.0038 | 0.0005 | 0.0089 | 0.0014 | 0.0335 | 0.0046 | 0.0772 | 0.0246 | 0.1392 | 0.0483 | 0.1512 | 0.0433 | 0.1980 | 0.0724 | 0.3871 | 0.8050 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0031 | 0.0000 | 0.0098 | 0.0013 | 0.0411 | 0.0183 | 0.0878 | 0.0404 | 0.0734 | 0.0243 | 0.1145 | 0.0469 | 0.6689 | 0.8688 | 0.0109 | 0.0189 | 0.0327 | 0.0189 | 0.0463 | 0.0566 | 0.1308 | 0.1509 | 0.1417 | 0.1887 | 0.1989 | 0.2264 | 0.1144 | 0.0943 | 0.1608 | 0.1321 | 0.1635 | 0.1132 | 0.0028 | 0.0123 | 0.0274 | 0.0482 | 0.1154 | 0.1703 | 0.1060 | 0.1552 | 0.3623 | 13 | 16 | 21 | 34 | 74 | 129 | 190 | 273 | 377 | 0.0284 | 57.62 | 5.532 | 0.4008 | 50997.4 | 24600000 | 14500000000 | 9660000000000 | 0.5052 | 0.1542 | 0.0789 | 0.0074 | 0.2366 | 0.0391 | 0.2258 | 0.1657 | 0.1075 | 0.1304 | 0.1004 | 0.1657 | 0.1183 | 0.1657 | 0.0824 | 0.1229 | 0.0323 | 0.0838 | 0.0179 | 0.1192 | 0.0017 | 0.0000 | 0.0017 | 0.0008 | 0.0051 | 0.0084 | 0.0146 | 0.0114 | 0.0788 | 0.0729 | 0.1311 | 0.1109 | 0.0874 | 0.0858 | 0.1482 | 0.1291 | 0.5313 | 0.5809 | 0.0011 | 0.0000 | 0.0045 | 0.0064 | 0.0124 | 0.0141 | 0.0236 | 0.0295 | 0.1025 | 0.1013 | 0.1577 | 0.1782 | 0.1092 | 0.1115 | 0.1441 | 0.1449 | 0.4448 | 0.4141 | 0.0020 | 0.0039 | 0.0039 | 0.0225 | 0.1000 | 0.1324 | 0.1049 | 0.1471 | 0.4833 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 974 | 491 | | 2075 | 6138 | 79.2 | 16.85 | 226.62 | 224.68 | 59 | 65 | 70 | 74 | 77 | 82 | 86 | 93 | 102 | 0.0632 | 388 | 0.768 | 127.88 | 34.79 | 1 | 0.1566 | 325 | 0.0032 | 15.64 | 6.011 | 0.2726 | 6562.2 | 567309 | 51100000 | 4800000000 | 0.4688 | 0.1916 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0073 | 0.0005 | 0.0278 | 0.0010 | 0.0805 | 0.0234 | 0.1426 | 0.0426 | 0.1500 | 0.0483 | 0.2004 | 0.0701 | 0.3899 | 0.8141 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0063 | 0.0000 | 0.0322 | 0.0138 | 0.0679 | 0.0256 | 0.0621 | 0.0177 | 0.1059 | 0.0290 | 0.7238 | 0.9140 | 0.0081 | 0.0370 | 0.0270 | 0.0278 | 0.0377 | 0.0926 | 0.0916 | 0.0833 | 0.1456 | 0.1759 | 0.1806 | 0.2407 | 0.1294 | 0.1204 | 0.1240 | 0.1852 | 0.2561 | 0.0370 | 0.0030 | 0.0071 | 0.0163 | 0.0346 | 0.0925 | 0.1209 | 0.1189 | 0.1423 | 0.4644 | 24 | 43 | 68 | 98 | 138 | 204 | 294 | 397 | 550 | 0.0072 | 49.76 | 6.356 | 0.3422 | 101826.0 | 62200000 | 45000000000 | 36400000000000 | 0.4500 | 0.1910 | 0.0311 | 0.0000 | 0.1627 | 0.0071 | 0.2825 | 0.0767 | 0.1686 | 0.1526 | 0.1361 | 0.1859 | 0.1124 | 0.2314 | 0.0503 | 0.1313 | 0.0355 | 0.0987 | 0.0207 | 0.1164 | 0.0008 | 0.0000 | 0.0023 | 0.0013 | 0.0011 | 0.0016 | 0.0106 | 0.0107 | 0.0513 | 0.0417 | 0.1124 | 0.1059 | 0.0724 | 0.0672 | 0.1116 | 0.0820 | 0.6376 | 0.6897 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0056 | 0.0077 | 0.0192 | 0.0195 | 0.0709 | 0.0936 | 0.1478 | 0.1647 | 0.1063 | 0.1043 | 0.1184 | 0.1345 | 0.5314 | 0.4716 | 0.0004 | 0.0013 | 0.0053 | 0.0149 | 0.0605 | 0.1329 | 0.0925 | 0.1136 | 0.5785 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 297 | 552 | | 14385 | 28437 | 82.4 | 25.65 | 78.88 | 67.92 | 54 | 61 | 67 | 72 | 78 | 84 | 92 | 102 | 118 | 0.0619 | 1760 | 0.262 | 166.21 | 32.56 | 3 | 0.0482 | 693 | 0.0019 | 19.35 | 6.626 | 0.2629 | 7444.0 | 736986 | 79600000 | 9310000000 | 0.4815 | 0.1870 | 0.0021 | 0.0003 | 0.0065 | 0.0003 | 0.0131 | 0.0021 | 0.0495 | 0.0068 | 0.1160 | 0.0333 | 0.1694 | 0.0768 | 0.1624 | 0.0699 | 0.1801 | 0.1101 | 0.3009 | 0.7002 | 0.0009 | 0.0001 | 0.0024 | 0.0002 | 0.0052 | 0.0010 | 0.0160 | 0.0027 | 0.0436 | 0.0170 | 0.0742 | 0.0391 | 0.0712 | 0.0313 | 0.0969 | 0.0550 | 0.6896 | 0.8537 | 0.0030 | 0.0071 | 0.0075 | 0.0071 | 0.0157 | 0.0308 | 0.0392 | 0.0711 | 0.1000 | 0.1257 | 0.1440 | 0.1814 | 0.1217 | 0.1209 | 0.1491 | 0.1375 | 0.4199 | 0.3183 | 0.0030 | 0.0033 | 0.0113 | 0.0296 | 0.0612 | 0.1057 | 0.0936 | 0.1170 | 0.5753 | 13 | 21 | 32 | 44 | 58 | 75 | 98 | 130 | 177 | 0.0288 | 3.28 | 4.562 | 0.5810 | 10835.9 | 2010000 | 449000000 | 114000000000 | 0.4815 | 0.2042 | 0.0179 | 0.0044 | 0.0831 | 0.0084 | 0.1602 | 0.0296 | 0.1876 | 0.0792 | 0.1946 | 0.1523 | 0.1540 | 0.1942 | 0.1033 | 0.1555 | 0.0667 | 0.1609 | 0.0325 | 0.2154 | 0.0015 | 0.0018 | 0.0051 | 0.0029 | 0.0095 | 0.0074 | 0.0231 | 0.0180 | 0.0558 | 0.0481 | 0.0860 | 0.0817 | 0.0704 | 0.0668 | 0.0931 | 0.0878 | 0.6555 | 0.6854 | 0.0035 | 0.0026 | 0.0057 | 0.0037 | 0.0118 | 0.0131 | 0.0292 | 0.0330 | 0.0623 | 0.0748 | 0.1026 | 0.1123 | 0.0901 | 0.1017 | 0.1112 | 0.1253 | 0.5837 | 0.5335 | 0.0017 | 0.0054 | 0.0113 | 0.0279 | 0.0579 | 0.0968 | 0.0744 | 0.1004 | 0.6242 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 993 | 394 | | 3513 | 2040 | 83.9 | 23.57 | 182.26 | 150.78 | 58 | 64 | 69 | 74 | 80 | 86 | 93 | 102 | 117 | 0.2098 | 428 | 0.610 | 126.40 | 36.89 | 1 | 0.1153 | 405 | 0.0023 | 17.58 | 6.355 | 0.2696 | 7588.6 | 740923 | 77800000 | 8750000000 | 0.4603 | 0.1930 | 0.0011 | 0.0000 | 0.0056 | 0.0007 | 0.0134 | 0.0026 | 0.0431 | 0.0082 | 0.0968 | 0.0264 | 0.1556 | 0.0541 | 0.1617 | 0.0463 | 0.1796 | 0.0825 | 0.3430 | 0.7792 | 0.0008 | 0.0000 | 0.0012 | 0.0003 | 0.0047 | 0.0003 | 0.0176 | 0.0029 | 0.0434 | 0.0159 | 0.0672 | 0.0308 | 0.0649 | 0.0238 | 0.0883 | 0.0443 | 0.7120 | 0.8816 | 0.0000 | 0.0059 | 0.0052 | 0.0059 | 0.0181 | 0.0265 | 0.0557 | 0.0649 | 0.0959 | 0.1150 | 0.1386 | 0.1593 | 0.1010 | 0.1062 | 0.1451 | 0.1386 | 0.4404 | 0.3776 | 0.0000 | 0.0059 | 0.0092 | 0.0301 | 0.0682 | 0.1009 | 0.0904 | 0.1193 | 0.5760 | 38 | 61 | 78 | 94 | 117 | 169 | 238 | 312 | 410 | 0.0064 | 25.03 | 5.822 | 0.3730 | 55941.1 | 22700000 | 10800000000 | 5710000000000 | 0.5146 | 0.1363 | 0.0251 | 0.0117 | 0.1967 | 0.0156 | 0.1799 | 0.0702 | 0.1674 | 0.1384 | 0.1632 | 0.2242 | 0.1297 | 0.1696 | 0.0795 | 0.1345 | 0.0418 | 0.1228 | 0.0167 | 0.1131 | 0.0011 | 0.0037 | 0.0055 | 0.0037 | 0.0033 | 0.0065 | 0.0199 | 0.0140 | 0.0719 | 0.0699 | 0.1062 | 0.0885 | 0.0752 | 0.0690 | 0.1195 | 0.1053 | 0.5973 | 0.6393 | 0.0000 | 0.0000 | 0.0015 | 0.0036 | 0.0075 | 0.0054 | 0.0256 | 0.0536 | 0.0902 | 0.1161 | 0.1504 | 0.1393 | 0.1158 | 0.1339 | 0.1504 | 0.1750 | 0.4586 | 0.3732 | 0.0000 | 0.0013 | 0.0051 | 0.0269 | 0.0654 | 0.1333 | 0.0885 | 0.1321 | 0.5474 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1041 | 916 | | 403 | 1181 | 80.5 | 10.16 | 173.50 | 253.63 | 67 | 70 | 74 | 77 | 80 | 84 | 86 | 90 | 94 | 0.2320 | 274 | 1.030 | 30.08 | 8.00 | 0 | 0.1762 | 71 | 0.1226 | 0.50 | 2.391 | 0.7876 | 6578.3 | 546175 | 46000000 | 3940000000 | 0.3807 | 0.2394 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0188 | 0.0124 | 0.0591 | 0.0422 | 0.1237 | 0.1166 | 0.1022 | 0.0422 | 0.1532 | 0.0794 | 0.5376 | 0.7072 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0176 | 0.0124 | 0.0403 | 0.0422 | 0.1159 | 0.1166 | 0.0554 | 0.0422 | 0.0781 | 0.0794 | 0.6902 | 0.7072 | 0.0800 | 0.0000 | 0.0800 | 0.0000 | 0.0000 | 0.0000 | 0.2000 | 0.0000 | 0.1200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0048 | 0.0000 | 0.0144 | 0.0383 | 0.1005 | 0.1340 | 0.0861 | 0.1627 | 0.4593 | 19 | 27 | 36 | 48 | 66 | 100 | 161 | 254 | 474 | 0.0380 | 54.53 | 4.632 | 0.4971 | 94375.3 | 84600000 | 95200000000 | 121000000000000 | 0.4414 | 0.1907 | 0.1038 | 0.0045 | 0.2264 | 0.0588 | 0.2170 | 0.1810 | 0.0472 | 0.1267 | 0.1415 | 0.2262 | 0.1321 | 0.1765 | 0.0943 | 0.0679 | 0.0189 | 0.0498 | 0.0189 | 0.1086 | 0.0000 | 0.0000 | 0.0026 | 0.0021 | 0.0026 | 0.0043 | 0.0490 | 0.0322 | 0.1108 | 0.1052 | 0.2010 | 0.1824 | 0.1031 | 0.0966 | 0.1237 | 0.1223 | 0.4072 | 0.4549 | 0.0035 | 0.0041 | 0.0142 | 0.0122 | 0.0284 | 0.0245 | 0.0674 | 0.0531 | 0.1418 | 0.1633 | 0.1596 | 0.1633 | 0.0887 | 0.0939 | 0.1348 | 0.1347 | 0.3617 | 0.3510 | 0.0030 | 0.0030 | 0.0119 | 0.0625 | 0.1310 | 0.1964 | 0.0923 | 0.1190 | 0.3810 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 702 | 223 | | 941 | 12390 | 79.6 | 29.54 | 182.48 | 238.48 | 36 | 53 | 62 | 72 | 81 | 87 | 96 | 106 | 120 | 0.0553 | 685 | 0.420 | 238.65 | 45.22 | 1 | 0.8013 | 754 | 0.0030 | 21.04 | 6.013 | 0.2638 | 7208.4 | 713221 | 75200000 | 8310000000 | 0.4207 | 0.1971 | 0.0028 | 0.0000 | 0.0140 | 0.0000 | 0.0955 | 0.0016 | 0.1124 | 0.0078 | 0.1376 | 0.0889 | 0.1713 | 0.1404 | 0.1292 | 0.1420 | 0.1573 | 0.1451 | 0.1798 | 0.4743 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0077 | 0.0025 | 0.0526 | 0.0406 | 0.0896 | 0.0570 | 0.0526 | 0.0456 | 0.0881 | 0.0646 | 0.7079 | 0.7896 | 0.0000 | 0.0068 | 0.0069 | 0.0000 | 0.0309 | 0.0270 | 0.0378 | 0.1216 | 0.1478 | 0.2027 | 0.1890 | 0.2027 | 0.1168 | 0.1757 | 0.1787 | 0.1622 | 0.2921 | 0.1014 | 0.0000 | 0.0020 | 0.0041 | 0.0244 | 0.0815 | 0.1120 | 0.1303 | 0.1589 | 0.4868 | 13 | 16 | 20 | 30 | 62 | 129 | 225 | 349 | 522 | 0.0743 | 27.27 | 5.116 | 0.5188 | 90166.0 | 64100000 | 58300000000 | 64100000000000 | 0.4933 | 0.1833 | 0.0624 | 0.0027 | 0.1895 | 0.0226 | 0.2793 | 0.1183 | 0.1763 | 0.1656 | 0.1490 | 0.2005 | 0.0876 | 0.1919 | 0.0394 | 0.1156 | 0.0153 | 0.1102 | 0.0011 | 0.0726 | 0.0004 | 0.0002 | 0.0023 | 0.0013 | 0.0047 | 0.0036 | 0.0157 | 0.0126 | 0.0591 | 0.0491 | 0.0882 | 0.0803 | 0.0608 | 0.0573 | 0.0914 | 0.0794 | 0.6774 | 0.7162 | 0.0005 | 0.0015 | 0.0024 | 0.0015 | 0.0061 | 0.0041 | 0.0198 | 0.0215 | 0.0614 | 0.0684 | 0.1002 | 0.1256 | 0.0833 | 0.0902 | 0.1091 | 0.1368 | 0.6172 | 0.5505 | 0.0019 | 0.0029 | 0.0038 | 0.0150 | 0.0588 | 0.0954 | 0.0711 | 0.1004 | 0.6507 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 118 | 70 | | 1754 | 4174 | 82.7 | 19.21 | 183.51 | 192.01 | 60 | 66 | 71 | 76 | 81 | 86 | 92 | 98 | 108 | 0.1445 | 603 | 0.362 | 172.26 | 45.00 | 1 | 0.4025 | 706 | 0.0023 | 27.82 | 6.291 | 0.2092 | 7207.4 | 660678 | 63600000 | 6400000000 | 0.4497 | 0.1988 | 0.0009 | 0.0000 | 0.0066 | 0.0000 | 0.0161 | 0.0031 | 0.0530 | 0.0093 | 0.1258 | 0.0322 | 0.1542 | 0.0811 | 0.1987 | 0.0619 | 0.2271 | 0.1002 | 0.2176 | 0.7123 | 0.0000 | 0.0000 | 0.0036 | 0.0000 | 0.0065 | 0.0017 | 0.0210 | 0.0035 | 0.0564 | 0.0239 | 0.0694 | 0.0554 | 0.0845 | 0.0309 | 0.1185 | 0.0612 | 0.6402 | 0.8233 | 0.0183 | 0.0101 | 0.0367 | 0.0202 | 0.0765 | 0.0808 | 0.1009 | 0.2121 | 0.1407 | 0.2323 | 0.1529 | 0.2222 | 0.1315 | 0.0909 | 0.1070 | 0.0909 | 0.2355 | 0.0404 | 0.0024 | 0.0120 | 0.0240 | 0.0456 | 0.0948 | 0.1116 | 0.1273 | 0.1645 | 0.4178 | 24 | 30 | 42 | 62 | 105 | 161 | 244 | 333 | 444 | 0.0173 | 43.47 | 5.837 | 0.3746 | 70533.6 | 37800000 | 24900000000 | 19100000000000 | 0.4742 | 0.1698 | 0.1259 | 0.0058 | 0.2370 | 0.0559 | 0.2840 | 0.2328 | 0.1457 | 0.1420 | 0.0889 | 0.1700 | 0.0617 | 0.1455 | 0.0420 | 0.0873 | 0.0099 | 0.0733 | 0.0049 | 0.0873 | 0.0011 | 0.0010 | 0.0028 | 0.0020 | 0.0091 | 0.0024 | 0.0300 | 0.0215 | 0.0935 | 0.0842 | 0.1230 | 0.1214 | 0.0941 | 0.0773 | 0.1423 | 0.1214 | 0.5040 | 0.5688 | 0.0007 | 0.0000 | 0.0059 | 0.0051 | 0.0074 | 0.0144 | 0.0368 | 0.0405 | 0.1177 | 0.1267 | 0.1575 | 0.1976 | 0.1302 | 0.1351 | 0.1707 | 0.1520 | 0.3731 | 0.3285 | 0.0013 | 0.0026 | 0.0059 | 0.0300 | 0.1019 | 0.1457 | 0.1130 | 0.1470 | 0.4526 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1169 | 718 | | 3803 | 6960 | 84.4 | 20.56 | 84.20 | 75.35 | 60 | 68 | 73 | 77 | 82 | 88 | 94 | 101 | 111 | 0.1295 | 901 | 1.055 | 100.65 | 36.80 | 3 | 0.0702 | 267 | 0.0048 | 9.98 | 5.662 | 0.3488 | 7539.7 | 712809 | 71300000 | 7550000000 | 0.4461 | 0.2010 | 0.0035 | 0.0000 | 0.0035 | 0.0006 | 0.0133 | 0.0014 | 0.0434 | 0.0049 | 0.1018 | 0.0301 | 0.1540 | 0.0703 | 0.1717 | 0.0627 | 0.1965 | 0.1162 | 0.3124 | 0.7138 | 0.0007 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0008 | 0.0141 | 0.0025 | 0.0434 | 0.0234 | 0.0736 | 0.0485 | 0.0696 | 0.0294 | 0.0923 | 0.0539 | 0.7024 | 0.8412 | 0.0038 | 0.0423 | 0.0153 | 0.0329 | 0.0204 | 0.0798 | 0.1008 | 0.1596 | 0.1288 | 0.1831 | 0.1760 | 0.2019 | 0.1492 | 0.1221 | 0.1620 | 0.0845 | 0.2436 | 0.0939 | 0.0016 | 0.0066 | 0.0131 | 0.0334 | 0.0826 | 0.1067 | 0.1100 | 0.1379 | 0.5082 | 21 | 29 | 36 | 45 | 57 | 72 | 93 | 129 | 196 | 0.0215 | 6.08 | 4.792 | 0.5469 | 12767.1 | 2810000 | 768000000 | 242000000000 | 0.5949 | 0.1190 | 0.0236 | 0.0027 | 0.0754 | 0.0155 | 0.1471 | 0.0354 | 0.1680 | 0.0787 | 0.1916 | 0.1437 | 0.1471 | 0.1641 | 0.1235 | 0.1433 | 0.0836 | 0.1636 | 0.0400 | 0.2530 | 0.0027 | 0.0010 | 0.0061 | 0.0052 | 0.0097 | 0.0081 | 0.0289 | 0.0240 | 0.0729 | 0.0672 | 0.1069 | 0.0930 | 0.0901 | 0.0750 | 0.1103 | 0.1066 | 0.5724 | 0.6198 | 0.0048 | 0.0038 | 0.0112 | 0.0038 | 0.0117 | 0.0102 | 0.0363 | 0.0326 | 0.0811 | 0.0856 | 0.1323 | 0.1475 | 0.0961 | 0.0958 | 0.1126 | 0.1315 | 0.5139 | 0.4891 | 0.0013 | 0.0093 | 0.0160 | 0.0388 | 0.0835 | 0.1210 | 0.0923 | 0.1151 | 0.5228 |