High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 780 | 643 | 4246 | 9503 | 153.2 | 43.23 | 163.95 | 111.35 | 107 | 118 | 127 | 135 | 144 | 155 | 167 | 184 | 213 | 0.0930 | 884 | 1.215 | 66.84 | 30.36 | 1 | 0.0445 | 189 | 0.0016 | 33.38 | 6.721 | 0.2068 | 25324.3 | 4540000 | 884000000 | 186000000000 | 0.4222 | 0.2177 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0065 | 0.0005 | 0.0285 | 0.0037 | 0.1085 | 0.0264 | 0.1876 | 0.0650 | 0.1746 | 0.0647 | 0.2040 | 0.0836 | 0.2891 | 0.7561 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0110 | 0.0012 | 0.0397 | 0.0171 | 0.0784 | 0.0293 | 0.0800 | 0.0238 | 0.1178 | 0.0358 | 0.6711 | 0.8927 | 0.0023 | 0.0000 | 0.0047 | 0.0049 | 0.0140 | 0.0196 | 0.0756 | 0.1225 | 0.1465 | 0.1716 | 0.1686 | 0.2059 | 0.1128 | 0.1152 | 0.1419 | 0.1127 | 0.3337 | 0.2475 | 0.0011 | 0.0022 | 0.0056 | 0.0332 | 0.0917 | 0.1507 | 0.1074 | 0.1277 | 0.4803 | 49 | 74 | 95 | 116 | 139 | 164 | 198 | 245 | 310 | 0.0019 | 44.15 | 6.783 | 0.2632 | 39278.6 | 12800000 | 5480000000 | 3000000000000 | 0.5562 | 0.1215 | 0.0241 | 0.0012 | 0.0805 | 0.0056 | 0.1411 | 0.0391 | 0.1416 | 0.0770 | 0.1754 | 0.1299 | 0.1546 | 0.1697 | 0.1157 | 0.1456 | 0.0995 | 0.1528 | 0.0676 | 0.2792 | 0.0014 | 0.0002 | 0.0026 | 0.0009 | 0.0069 | 0.0057 | 0.0242 | 0.0137 | 0.0746 | 0.0545 | 0.1063 | 0.0876 | 0.0950 | 0.0778 | 0.1295 | 0.1115 | 0.5595 | 0.6480 | 0.0031 | 0.0018 | 0.0045 | 0.0054 | 0.0118 | 0.0145 | 0.0478 | 0.0559 | 0.1069 | 0.1335 | 0.1491 | 0.1807 | 0.1301 | 0.1326 | 0.1557 | 0.1685 | 0.3910 | 0.3070 | 0.0018 | 0.0050 | 0.0089 | 0.0404 | 0.0908 | 0.1409 | 0.1049 | 0.1375 | 0.4699 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1018 | 588 | 3811 | 2194 | 152.8 | 45.25 | 165.29 | 120.38 | 109 | 118 | 126 | 134 | 142 | 151 | 164 | 180 | 214 | 0.2334 | 512 | 1.053 | 95.88 | 21.84 | 1 | 0.0559 | 213 | 0.0019 | 30.81 | 6.595 | 0.2281 | 25408.3 | 4650000 | 946000000 | 214000000000 | 0.3988 | 0.2432 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0266 | 0.0015 | 0.1000 | 0.0318 | 0.1613 | 0.0588 | 0.1678 | 0.0558 | 0.1730 | 0.0780 | 0.3604 | 0.7742 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0145 | 0.0008 | 0.0469 | 0.0184 | 0.0800 | 0.0301 | 0.0793 | 0.0235 | 0.0959 | 0.0379 | 0.6781 | 0.8893 | 0.0014 | 0.0000 | 0.0201 | 0.0000 | 0.0086 | 0.0026 | 0.0459 | 0.0741 | 0.1119 | 0.1481 | 0.1607 | 0.1984 | 0.0947 | 0.1085 | 0.1349 | 0.1614 | 0.4218 | 0.3069 | 0.0040 | 0.0094 | 0.0101 | 0.0330 | 0.0808 | 0.1359 | 0.0969 | 0.1151 | 0.5148 | 45 | 64 | 85 | 108 | 136 | 167 | 200 | 252 | 322 | 0.0021 | 74.42 | 6.577 | 0.2161 | 41805.4 | 14100000 | 5770000000 | 2690000000000 | 0.5152 | 0.1357 | 0.0346 | 0.0000 | 0.1364 | 0.0171 | 0.2165 | 0.0798 | 0.1667 | 0.1277 | 0.1688 | 0.1631 | 0.1190 | 0.1836 | 0.0909 | 0.1072 | 0.0455 | 0.1482 | 0.0216 | 0.1733 | 0.0000 | 0.0000 | 0.0009 | 0.0014 | 0.0097 | 0.0043 | 0.0292 | 0.0264 | 0.1205 | 0.0785 | 0.1763 | 0.1527 | 0.1045 | 0.0935 | 0.1523 | 0.1456 | 0.4066 | 0.4975 | 0.0030 | 0.0057 | 0.0045 | 0.0038 | 0.0285 | 0.0286 | 0.0615 | 0.0782 | 0.1529 | 0.1794 | 0.2144 | 0.2271 | 0.1229 | 0.1355 | 0.1439 | 0.1240 | 0.2684 | 0.2176 | 0.0011 | 0.0034 | 0.0202 | 0.0506 | 0.1406 | 0.1755 | 0.1260 | 0.1586 | 0.3240 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 359 | 542 | 4621 | 10762 | 146.2 | 33.43 | 222.69 | 177.49 | 107 | 118 | 125 | 134 | 142 | 151 | 161 | 172 | 191 | 0.0783 | 843 | 0.885 | 76.16 | 18.03 | 1 | 0.0390 | 180 | 0.0019 | 23.24 | 6.525 | 0.2373 | 22484.2 | 3640000 | 620000000 | 111000000000 | 0.4346 | 0.2115 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0058 | 0.0002 | 0.0194 | 0.0023 | 0.0890 | 0.0207 | 0.1549 | 0.0458 | 0.1876 | 0.0490 | 0.2146 | 0.0759 | 0.3279 | 0.8061 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0024 | 0.0002 | 0.0059 | 0.0009 | 0.0386 | 0.0147 | 0.0709 | 0.0249 | 0.0768 | 0.0190 | 0.1183 | 0.0332 | 0.6866 | 0.9071 | 0.0061 | 0.0150 | 0.0207 | 0.0187 | 0.0292 | 0.0487 | 0.0901 | 0.1423 | 0.1681 | 0.1723 | 0.1791 | 0.2247 | 0.1108 | 0.1086 | 0.1462 | 0.1236 | 0.2497 | 0.1461 | 0.0009 | 0.0043 | 0.0080 | 0.0326 | 0.0913 | 0.1456 | 0.1210 | 0.1504 | 0.4459 | 44 | 73 | 105 | 144 | 183 | 226 | 275 | 342 | 445 | 0.0015 | 74.52 | 7.246 | 0.2302 | 81090.3 | 40900000 | 26000000000 | 19500000000000 | 0.4630 | 0.1957 | 0.0142 | 0.0014 | 0.0752 | 0.0062 | 0.1565 | 0.0283 | 0.1896 | 0.0627 | 0.1844 | 0.1479 | 0.1697 | 0.2060 | 0.1092 | 0.1512 | 0.0700 | 0.1579 | 0.0312 | 0.2384 | 0.0009 | 0.0003 | 0.0020 | 0.0012 | 0.0062 | 0.0036 | 0.0222 | 0.0121 | 0.0621 | 0.0464 | 0.1076 | 0.0967 | 0.0994 | 0.0695 | 0.1261 | 0.1058 | 0.5735 | 0.6645 | 0.0015 | 0.0019 | 0.0047 | 0.0070 | 0.0174 | 0.0174 | 0.0375 | 0.0557 | 0.0962 | 0.1161 | 0.1535 | 0.1663 | 0.1125 | 0.1199 | 0.1367 | 0.1389 | 0.4401 | 0.3768 | 0.0007 | 0.0043 | 0.0107 | 0.0285 | 0.0859 | 0.1281 | 0.1071 | 0.1381 | 0.4965 | |
SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 607 | 425 | 710 | 2523 | 137.3 | 19.50 | 92.60 | 84.78 | 108 | 118 | 127 | 136 | 142 | 146 | 151 | 155 | 160 | 0.1550 | 391 | 0.898 | 77.52 | 25.50 | 1 | 0.3000 | 213 | 0.0194 | 2.48 | 4.222 | 0.5165 | 19229.6 | 2740000 | 397000000 | 58100000000 | 0.3917 | 0.2405 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0028 | 0.0547 | 0.0310 | 0.0547 | 0.0648 | 0.0813 | 0.0254 | 0.1360 | 0.0394 | 0.6617 | 0.8366 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0111 | 0.0028 | 0.0446 | 0.0310 | 0.0350 | 0.0648 | 0.0398 | 0.0254 | 0.0653 | 0.0394 | 0.8041 | 0.8366 | 0.1200 | 0.0000 | 0.2000 | 0.0000 | 0.3200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0290 | 0.0338 | 0.0531 | 0.0628 | 0.0773 | 0.7440 | 21 | 29 | 40 | 53 | 69 | 84 | 105 | 131 | 195 | 0.0217 | 5.49 | 4.593 | 0.5505 | 15759.1 | 4090000 | 1360000000 | 524000000000 | 0.5327 | 0.1397 | 0.0216 | 0.0021 | 0.0747 | 0.0164 | 0.0943 | 0.0472 | 0.1179 | 0.0626 | 0.1473 | 0.1067 | 0.1866 | 0.1456 | 0.1218 | 0.1292 | 0.1257 | 0.1518 | 0.1100 | 0.3385 | 0.0000 | 0.0014 | 0.0085 | 0.0041 | 0.0136 | 0.0135 | 0.0298 | 0.0230 | 0.0562 | 0.0594 | 0.1285 | 0.0939 | 0.0809 | 0.0689 | 0.1260 | 0.1060 | 0.5566 | 0.6300 | 0.0030 | 0.0099 | 0.0120 | 0.0059 | 0.0150 | 0.0198 | 0.0435 | 0.0435 | 0.0901 | 0.1087 | 0.1667 | 0.1601 | 0.0901 | 0.1186 | 0.1396 | 0.1719 | 0.4399 | 0.3617 | 0.0056 | 0.0134 | 0.0134 | 0.0335 | 0.0838 | 0.1173 | 0.1039 | 0.1363 | 0.4927 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 160 | 559 | 777 | 9070 | 142.8 | 24.42 | 9.70 | 3.50 | 112 | 118 | 126 | 133 | 140 | 148 | 158 | 166 | 176 | 0.0568 | 515 | 1.054 | 31.06 | 11.31 | 2 | 0.1055 | 82 | 0.0343 | 0.90 | 3.554 | 0.6764 | 20980.7 | 3170000 | 492000000 | 78100000000 | 0.3567 | 0.2774 | 0.0018 | 0.0000 | 0.0054 | 0.0000 | 0.0108 | 0.0000 | 0.0324 | 0.0052 | 0.0486 | 0.0297 | 0.0845 | 0.0568 | 0.0899 | 0.0375 | 0.1367 | 0.0672 | 0.5899 | 0.8036 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0060 | 0.0000 | 0.0120 | 0.0051 | 0.0300 | 0.0296 | 0.0556 | 0.0566 | 0.0390 | 0.0335 | 0.0691 | 0.0463 | 0.7868 | 0.8288 | 0.0000 | 0.3333 | 0.0273 | 0.6667 | 0.0545 | 0.0000 | 0.0909 | 0.0000 | 0.0545 | 0.0000 | 0.1273 | 0.0000 | 0.1364 | 0.0000 | 0.1545 | 0.0000 | 0.3545 | 0.0000 | 0.0027 | 0.0082 | 0.0164 | 0.0274 | 0.0521 | 0.0438 | 0.0712 | 0.0904 | 0.6877 | 5 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 14 | 0.3521 | 0.32 | 0.913 | 0.7078 | 106.3 | 1283.9 | 16775.6 | 233954 | 0.5201 | 0.1454 | 0.0253 | 0.0006 | 0.0903 | 0.0051 | 0.1671 | 0.0191 | 0.2366 | 0.0551 | 0.2191 | 0.1221 | 0.1546 | 0.1819 | 0.0752 | 0.2234 | 0.0261 | 0.2369 | 0.0057 | 0.1558 | 0.0061 | 0.0002 | 0.0215 | 0.0009 | 0.0425 | 0.0040 | 0.0618 | 0.0164 | 0.0849 | 0.0497 | 0.0987 | 0.0844 | 0.1341 | 0.1082 | 0.2235 | 0.1971 | 0.3269 | 0.5392 | 0.0656 | 0.0964 | 0.0810 | 0.1782 | 0.1177 | 0.2345 | 0.1625 | 0.2235 | 0.1694 | 0.1497 | 0.1640 | 0.0679 | 0.1374 | 0.0336 | 0.0780 | 0.0110 | 0.0243 | 0.0051 | 0.0347 | 0.0481 | 0.0556 | 0.0753 | 0.0996 | 0.1448 | 0.1879 | 0.2108 | 0.1433 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 320 | 667 | 5012 | 4003 | 144.6 | 31.00 | 256.96 | 210.61 | 110 | 119 | 126 | 133 | 139 | 146 | 155 | 168 | 187 | 0.1699 | 680 | 1.061 | 130.67 | 36.72 | 1 | 0.0599 | 300 | 0.0023 | 22.41 | 6.404 | 0.2450 | 21873.6 | 3470000 | 577000000 | 101000000000 | 0.4357 | 0.2084 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0059 | 0.0000 | 0.0223 | 0.0013 | 0.0711 | 0.0189 | 0.1355 | 0.0456 | 0.1443 | 0.0439 | 0.1875 | 0.0634 | 0.4320 | 0.8269 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0083 | 0.0004 | 0.0355 | 0.0130 | 0.0649 | 0.0252 | 0.0675 | 0.0144 | 0.0966 | 0.0244 | 0.7237 | 0.9225 | 0.0073 | 0.0036 | 0.0158 | 0.0144 | 0.0280 | 0.0758 | 0.0767 | 0.1516 | 0.1571 | 0.1913 | 0.1705 | 0.1733 | 0.1255 | 0.1264 | 0.1437 | 0.1155 | 0.2753 | 0.1480 | 0.0038 | 0.0080 | 0.0127 | 0.0363 | 0.0930 | 0.1303 | 0.1085 | 0.1567 | 0.4507 | 33 | 63 | 100 | 155 | 208 | 265 | 333 | 424 | 568 | 0.0020 | 118.54 | 7.148 | 0.2176 | 110371.0 | 60900000 | 39200000000 | 28100000000000 | 0.4840 | 0.1833 | 0.0323 | 0.0038 | 0.1232 | 0.0212 | 0.2097 | 0.0613 | 0.2097 | 0.1272 | 0.1730 | 0.1779 | 0.1510 | 0.2059 | 0.0587 | 0.1476 | 0.0293 | 0.1272 | 0.0132 | 0.1279 | 0.0005 | 0.0000 | 0.0055 | 0.0033 | 0.0099 | 0.0087 | 0.0307 | 0.0229 | 0.0823 | 0.0715 | 0.1368 | 0.1227 | 0.1011 | 0.0932 | 0.1293 | 0.1165 | 0.5040 | 0.5611 | 0.0007 | 0.0055 | 0.0045 | 0.0028 | 0.0112 | 0.0148 | 0.0389 | 0.0572 | 0.1243 | 0.1210 | 0.1534 | 0.1681 | 0.1213 | 0.1385 | 0.1445 | 0.1376 | 0.4012 | 0.3546 | 0.0030 | 0.0066 | 0.0156 | 0.0361 | 0.0968 | 0.1437 | 0.1203 | 0.1371 | 0.4408 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 898 | 503 | 7597 | 15942 | 143.4 | 27.73 | 173.50 | 120.68 | 110 | 119 | 126 | 132 | 140 | 148 | 157 | 168 | 183 | 0.0661 | 1053 | 1.190 | 84.90 | 37.16 | 1 | 0.0309 | 235 | 0.0025 | 15.67 | 6.274 | 0.2752 | 21329.9 | 3290000 | 525000000 | 86500000000 | 0.4372 | 0.2078 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0046 | 0.0001 | 0.0191 | 0.0007 | 0.0570 | 0.0136 | 0.1188 | 0.0324 | 0.1394 | 0.0300 | 0.1797 | 0.0527 | 0.4799 | 0.8705 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0096 | 0.0000 | 0.0278 | 0.0107 | 0.0488 | 0.0198 | 0.0578 | 0.0112 | 0.0842 | 0.0195 | 0.7694 | 0.9388 | 0.0070 | 0.0409 | 0.0141 | 0.0591 | 0.0273 | 0.0955 | 0.0703 | 0.1955 | 0.1453 | 0.2727 | 0.1641 | 0.1500 | 0.1258 | 0.0545 | 0.1516 | 0.0864 | 0.2945 | 0.0455 | 0.0017 | 0.0034 | 0.0095 | 0.0337 | 0.0685 | 0.1129 | 0.1067 | 0.1314 | 0.5322 | 41 | 69 | 95 | 120 | 148 | 179 | 215 | 264 | 340 | 0.0019 | 36.17 | 6.887 | 0.2809 | 44665.2 | 14900000 | 5940000000 | 2730000000000 | 0.4612 | 0.1723 | 0.0167 | 0.0012 | 0.0841 | 0.0062 | 0.1709 | 0.0303 | 0.1727 | 0.0682 | 0.1885 | 0.1425 | 0.1471 | 0.1913 | 0.0984 | 0.1576 | 0.0707 | 0.1542 | 0.0507 | 0.2485 | 0.0012 | 0.0005 | 0.0036 | 0.0018 | 0.0077 | 0.0047 | 0.0185 | 0.0109 | 0.0606 | 0.0516 | 0.1144 | 0.0972 | 0.0887 | 0.0746 | 0.1158 | 0.0983 | 0.5895 | 0.6604 | 0.0006 | 0.0021 | 0.0065 | 0.0130 | 0.0156 | 0.0199 | 0.0449 | 0.0483 | 0.1050 | 0.1174 | 0.1463 | 0.1612 | 0.1156 | 0.1174 | 0.1360 | 0.1333 | 0.4295 | 0.3874 | 0.0013 | 0.0034 | 0.0091 | 0.0235 | 0.0795 | 0.1362 | 0.1016 | 0.1281 | 0.5171 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 448 | 583 | 4870 | 11803 | 145.2 | 35.55 | 166.28 | 141.22 | 106 | 119 | 129 | 136 | 143 | 150 | 157 | 166 | 182 | 0.0848 | 1001 | 1.080 | 90.80 | 26.02 | 1 | 0.0448 | 218 | 0.0023 | 21.25 | 6.376 | 0.2593 | 22352.9 | 3700000 | 674000000 | 140000000000 | 0.5233 | 0.1537 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0063 | 0.0020 | 0.0186 | 0.0059 | 0.0714 | 0.0204 | 0.1461 | 0.0576 | 0.1467 | 0.0492 | 0.1833 | 0.0730 | 0.4263 | 0.7916 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0017 | 0.0013 | 0.0087 | 0.0044 | 0.0397 | 0.0176 | 0.0788 | 0.0439 | 0.0694 | 0.0279 | 0.1031 | 0.0468 | 0.6983 | 0.8580 | 0.0071 | 0.0138 | 0.0228 | 0.0276 | 0.0342 | 0.0369 | 0.1198 | 0.1244 | 0.1641 | 0.1982 | 0.1897 | 0.1935 | 0.1227 | 0.0599 | 0.1098 | 0.1152 | 0.2297 | 0.2304 | 0.0030 | 0.0056 | 0.0155 | 0.0494 | 0.0975 | 0.1375 | 0.1224 | 0.1538 | 0.4154 | 18 | 39 | 68 | 100 | 133 | 170 | 213 | 270 | 362 | 0.0037 | 57.89 | 6.920 | 0.2988 | 47591.3 | 18100000 | 8370000000 | 4450000000000 | 0.4521 | 0.1774 | 0.0099 | 0.0010 | 0.0727 | 0.0018 | 0.1824 | 0.0223 | 0.1760 | 0.0674 | 0.2042 | 0.1490 | 0.1715 | 0.2039 | 0.0989 | 0.1663 | 0.0578 | 0.1655 | 0.0267 | 0.2229 | 0.0002 | 0.0000 | 0.0010 | 0.0008 | 0.0039 | 0.0034 | 0.0108 | 0.0072 | 0.0510 | 0.0340 | 0.0877 | 0.0683 | 0.0730 | 0.0617 | 0.1087 | 0.0831 | 0.6637 | 0.7415 | 0.0013 | 0.0019 | 0.0013 | 0.0061 | 0.0077 | 0.0145 | 0.0286 | 0.0352 | 0.0848 | 0.1044 | 0.1358 | 0.1322 | 0.1054 | 0.1131 | 0.1247 | 0.1251 | 0.5106 | 0.4674 | 0.0006 | 0.0029 | 0.0045 | 0.0181 | 0.0642 | 0.1082 | 0.0990 | 0.1199 | 0.5826 | |||
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 469 | 396 | 3985 | 3374 | 160.1 | 46.65 | 190.25 | 141.76 | 107 | 121 | 132 | 142 | 153 | 165 | 177 | 195 | 221 | 0.2110 | 712 | 0.988 | 83.24 | 28.02 | 1 | 0.0575 | 229 | 0.0012 | 50.08 | 6.991 | 0.1783 | 27806.5 | 5240000 | 1070000000 | 235000000000 | 0.4379 | 0.2135 | 0.0010 | 0.0000 | 0.0005 | 0.0000 | 0.0144 | 0.0017 | 0.0460 | 0.0032 | 0.1321 | 0.0326 | 0.1991 | 0.0843 | 0.1709 | 0.0837 | 0.1728 | 0.1160 | 0.2633 | 0.6784 | 0.0007 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0003 | 0.0098 | 0.0016 | 0.0480 | 0.0199 | 0.0912 | 0.0482 | 0.0784 | 0.0364 | 0.0966 | 0.0566 | 0.6743 | 0.8371 | 0.0069 | 0.0079 | 0.0023 | 0.0237 | 0.0230 | 0.0211 | 0.0746 | 0.0868 | 0.1389 | 0.2237 | 0.1929 | 0.2053 | 0.1114 | 0.0974 | 0.1389 | 0.1316 | 0.3111 | 0.2026 | 0.0017 | 0.0017 | 0.0067 | 0.0274 | 0.1016 | 0.1496 | 0.1111 | 0.1407 | 0.4595 | 58 | 75 | 93 | 117 | 144 | 179 | 227 | 297 | 404 | 0.0022 | 69.15 | 6.693 | 0.2400 | 56286.8 | 22200000 | 10500000000 | 5560000000000 | 0.5618 | 0.1030 | 0.0253 | 0.0040 | 0.1149 | 0.0127 | 0.2821 | 0.0573 | 0.1909 | 0.1131 | 0.1740 | 0.1863 | 0.1166 | 0.2126 | 0.0439 | 0.1242 | 0.0389 | 0.1449 | 0.0135 | 0.1449 | 0.0006 | 0.0019 | 0.0025 | 0.0029 | 0.0125 | 0.0058 | 0.0368 | 0.0277 | 0.1085 | 0.0893 | 0.1696 | 0.1422 | 0.1103 | 0.1053 | 0.1490 | 0.1465 | 0.4102 | 0.4784 | 0.0049 | 0.0037 | 0.0069 | 0.0075 | 0.0208 | 0.0298 | 0.0573 | 0.0658 | 0.1285 | 0.1466 | 0.1887 | 0.1814 | 0.1176 | 0.1379 | 0.1542 | 0.1466 | 0.3211 | 0.2807 | 0.0016 | 0.0071 | 0.0158 | 0.0434 | 0.1278 | 0.1838 | 0.1112 | 0.1546 | 0.3549 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 937 | 869 | 4358 | 4787 | 150.5 | 35.67 | 215.35 | 167.50 | 110 | 121 | 130 | 138 | 145 | 153 | 163 | 177 | 197 | 0.1249 | 598 | 1.001 | 107.62 | 26.02 | 1 | 0.0569 | 248 | 0.0019 | 28.98 | 6.582 | 0.2338 | 23927.0 | 4030000 | 718000000 | 136000000000 | 0.4618 | 0.1848 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0307 | 0.0025 | 0.0928 | 0.0234 | 0.1506 | 0.0557 | 0.1593 | 0.0605 | 0.1827 | 0.0891 | 0.3778 | 0.7688 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0113 | 0.0009 | 0.0423 | 0.0174 | 0.0675 | 0.0300 | 0.0805 | 0.0244 | 0.1032 | 0.0449 | 0.6920 | 0.8824 | 0.0053 | 0.0070 | 0.0119 | 0.0105 | 0.0185 | 0.0281 | 0.0793 | 0.1333 | 0.1506 | 0.2702 | 0.2127 | 0.1754 | 0.1136 | 0.1053 | 0.1532 | 0.1368 | 0.2550 | 0.1333 | 0.0032 | 0.0048 | 0.0117 | 0.0472 | 0.0881 | 0.1342 | 0.1146 | 0.1363 | 0.4599 | 40 | 68 | 99 | 133 | 170 | 220 | 274 | 347 | 446 | 0.0016 | 96.66 | 7.105 | 0.2131 | 74423.1 | 33600000 | 18100000000 | 10900000000000 | 0.5058 | 0.1647 | 0.0429 | 0.0024 | 0.1767 | 0.0102 | 0.2798 | 0.0783 | 0.1951 | 0.1428 | 0.1325 | 0.2055 | 0.0994 | 0.2127 | 0.0393 | 0.1350 | 0.0172 | 0.1183 | 0.0172 | 0.0950 | 0.0008 | 0.0007 | 0.0013 | 0.0020 | 0.0029 | 0.0038 | 0.0256 | 0.0133 | 0.0797 | 0.0673 | 0.1472 | 0.1206 | 0.1065 | 0.0823 | 0.1254 | 0.1209 | 0.5107 | 0.5891 | 0.0000 | 0.0016 | 0.0051 | 0.0048 | 0.0134 | 0.0104 | 0.0535 | 0.0670 | 0.1217 | 0.1316 | 0.1637 | 0.2041 | 0.1312 | 0.1276 | 0.1548 | 0.1515 | 0.3567 | 0.3014 | 0.0010 | 0.0035 | 0.0051 | 0.0238 | 0.1190 | 0.1570 | 0.1023 | 0.1489 | 0.4392 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1017 | 174 | 1248 | 1851 | 214.5 | 155.04 | 45.32 | 44.12 | 105 | 122 | 135 | 145 | 159 | 175 | 196 | 246 | 453 | 0.2150 | 398 | 0.886 | 138.05 | 45.25 | 2 | 0.3045 | 380 | 0.0030 | 54.71 | 6.166 | 0.2695 | 70037.8 | 33300000 | 19600000000 | 12700000000000 | 0.3408 | 0.2642 | 0.0000 | 0.0014 | 0.0105 | 0.0000 | 0.0592 | 0.0027 | 0.0941 | 0.0095 | 0.2056 | 0.0846 | 0.1638 | 0.1419 | 0.0906 | 0.1132 | 0.1289 | 0.1050 | 0.2474 | 0.5416 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0076 | 0.0011 | 0.0191 | 0.0085 | 0.0841 | 0.0512 | 0.1071 | 0.0800 | 0.0650 | 0.0597 | 0.1071 | 0.0778 | 0.6099 | 0.7207 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0169 | 0.0098 | 0.0805 | 0.1073 | 0.1059 | 0.1024 | 0.0551 | 0.0488 | 0.0975 | 0.1024 | 0.6441 | 0.6293 | 0.0032 | 0.0097 | 0.0097 | 0.0130 | 0.0909 | 0.0942 | 0.0390 | 0.1039 | 0.6364 | 20 | 22 | 25 | 27 | 30 | 34 | 39 | 51 | 87 | 0.1634 | 0.96 | 2.528 | 0.7872 | 4000.0 | 623754 | 127000000 | 29000000000 | 0.5672 | 0.0956 | 0.0344 | 0.0145 | 0.0875 | 0.0190 | 0.1375 | 0.0335 | 0.1313 | 0.0760 | 0.1906 | 0.1229 | 0.2000 | 0.1508 | 0.1156 | 0.1620 | 0.0688 | 0.1721 | 0.0344 | 0.2492 | 0.0106 | 0.0111 | 0.0257 | 0.0146 | 0.0287 | 0.0231 | 0.0332 | 0.0446 | 0.0861 | 0.0788 | 0.1344 | 0.0925 | 0.1239 | 0.1071 | 0.1360 | 0.1500 | 0.4215 | 0.4781 | 0.0029 | 0.0037 | 0.0088 | 0.0368 | 0.0205 | 0.0404 | 0.0526 | 0.0772 | 0.1404 | 0.0919 | 0.1725 | 0.1287 | 0.1023 | 0.1213 | 0.1287 | 0.1103 | 0.3713 | 0.3897 | 0.0022 | 0.0155 | 0.0310 | 0.0376 | 0.1062 | 0.1372 | 0.1261 | 0.1482 | 0.3960 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 559 | 397 | 4059 | 4987 | 157.3 | 43.64 | 166.74 | 137.41 | 113 | 123 | 131 | 139 | 148 | 157 | 168 | 187 | 216 | 0.1313 | 655 | 1.114 | 90.61 | 28.23 | 1 | 0.0532 | 216 | 0.0019 | 30.80 | 6.626 | 0.2263 | 26652.8 | 4910000 | 989000000 | 219000000000 | 0.4120 | 0.2290 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0082 | 0.0005 | 0.0341 | 0.0027 | 0.0928 | 0.0269 | 0.1428 | 0.0626 | 0.1670 | 0.0541 | 0.1833 | 0.0802 | 0.3697 | 0.7729 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0039 | 0.0002 | 0.0135 | 0.0015 | 0.0410 | 0.0154 | 0.0693 | 0.0336 | 0.0738 | 0.0197 | 0.1013 | 0.0351 | 0.6956 | 0.8945 | 0.0051 | 0.0053 | 0.0064 | 0.0132 | 0.0128 | 0.0079 | 0.0370 | 0.1164 | 0.1392 | 0.1138 | 0.1520 | 0.2063 | 0.1137 | 0.1190 | 0.1494 | 0.1349 | 0.3844 | 0.2831 | 0.0006 | 0.0043 | 0.0188 | 0.0389 | 0.0832 | 0.1269 | 0.1014 | 0.1263 | 0.4997 | 31 | 49 | 69 | 94 | 126 | 164 | 210 | 272 | 369 | 0.0031 | 48.39 | 6.631 | 0.2926 | 46678.1 | 17300000 | 7530000000 | 3680000000000 | 0.5082 | 0.1638 | 0.0343 | 0.0038 | 0.1220 | 0.0131 | 0.1792 | 0.0451 | 0.1868 | 0.1264 | 0.1753 | 0.1496 | 0.1334 | 0.2034 | 0.0940 | 0.1508 | 0.0445 | 0.1189 | 0.0305 | 0.1890 | 0.0004 | 0.0007 | 0.0034 | 0.0014 | 0.0038 | 0.0031 | 0.0290 | 0.0239 | 0.0720 | 0.0560 | 0.1195 | 0.1000 | 0.0909 | 0.0796 | 0.1136 | 0.1058 | 0.5673 | 0.6295 | 0.0025 | 0.0023 | 0.0019 | 0.0023 | 0.0120 | 0.0232 | 0.0340 | 0.0518 | 0.1051 | 0.1044 | 0.1385 | 0.1353 | 0.0906 | 0.1067 | 0.1284 | 0.1276 | 0.4871 | 0.4462 | 0.0000 | 0.0061 | 0.0096 | 0.0289 | 0.0851 | 0.1327 | 0.0917 | 0.1155 | 0.5304 | |
MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 367 | 527 | 14166 | 30978 | 166.3 | 51.48 | 150.74 | 180.13 | 108 | 123 | 136 | 147 | 158 | 171 | 186 | 207 | 241 | 0.0455 | 1410 | 1.186 | 107.56 | 39.85 | 4 | 0.0193 | 274 | 0.0029 | 11.78 | 6.212 | 0.3232 | 30318.4 | 6020000 | 1290000000 | 298000000000 | 0.4567 | 0.2012 | 0.0010 | 0.0002 | 0.0020 | 0.0003 | 0.0095 | 0.0011 | 0.0293 | 0.0063 | 0.0939 | 0.0301 | 0.1627 | 0.0648 | 0.1523 | 0.0591 | 0.1747 | 0.0901 | 0.3747 | 0.7480 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0027 | 0.0002 | 0.0099 | 0.0021 | 0.0378 | 0.0155 | 0.0638 | 0.0296 | 0.0626 | 0.0267 | 0.0911 | 0.0439 | 0.7313 | 0.8820 | 0.0021 | 0.0018 | 0.0049 | 0.0083 | 0.0147 | 0.0155 | 0.0350 | 0.0596 | 0.0936 | 0.1173 | 0.1393 | 0.1757 | 0.0967 | 0.1203 | 0.1362 | 0.1471 | 0.4774 | 0.3544 | 0.0008 | 0.0034 | 0.0088 | 0.0319 | 0.0709 | 0.1074 | 0.0856 | 0.1046 | 0.5866 | 8 | 10 | 15 | 33 | 75 | 129 | 195 | 283 | 413 | 0.0651 | 14.33 | 5.012 | 0.4997 | 55169.9 | 27400000 | 16300000000 | 11100000000000 | 0.5068 | 0.1638 | 0.0376 | 0.0026 | 0.1800 | 0.0101 | 0.2471 | 0.0930 | 0.1592 | 0.1413 | 0.1404 | 0.1940 | 0.1108 | 0.1938 | 0.0625 | 0.1310 | 0.0393 | 0.1131 | 0.0232 | 0.1211 | 0.0002 | 0.0002 | 0.0005 | 0.0001 | 0.0016 | 0.0012 | 0.0097 | 0.0069 | 0.0522 | 0.0426 | 0.0886 | 0.0730 | 0.0686 | 0.0557 | 0.1054 | 0.0879 | 0.6732 | 0.7326 | 0.0004 | 0.0006 | 0.0015 | 0.0020 | 0.0027 | 0.0051 | 0.0177 | 0.0220 | 0.0740 | 0.0904 | 0.1206 | 0.1278 | 0.0882 | 0.0952 | 0.1271 | 0.1330 | 0.5678 | 0.5239 | 0.0000 | 0.0020 | 0.0028 | 0.0144 | 0.0620 | 0.1077 | 0.0815 | 0.1152 | 0.6146 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 394 | 413 | 10632 | 28722 | 169.7 | 54.58 | 192.66 | 182.13 | 104 | 123 | 136 | 150 | 164 | 180 | 197 | 216 | 243 | 0.0521 | 1497 | 0.576 | 118.81 | 23.02 | 3 | 0.0271 | 288 | 0.0008 | 43.75 | 7.350 | 0.1857 | 31777.4 | 6480000 | 1420000000 | 333000000000 | 0.4827 | 0.1836 | 0.0013 | 0.0000 | 0.0034 | 0.0005 | 0.0185 | 0.0025 | 0.0583 | 0.0094 | 0.1357 | 0.0376 | 0.2026 | 0.0859 | 0.1755 | 0.0911 | 0.1662 | 0.1246 | 0.2386 | 0.6485 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0027 | 0.0009 | 0.0142 | 0.0049 | 0.0416 | 0.0211 | 0.0761 | 0.0422 | 0.0667 | 0.0367 | 0.0911 | 0.0553 | 0.7060 | 0.8389 | 0.0022 | 0.0080 | 0.0032 | 0.0048 | 0.0097 | 0.0177 | 0.0479 | 0.1054 | 0.1186 | 0.1826 | 0.1586 | 0.1955 | 0.1287 | 0.1086 | 0.1536 | 0.1561 | 0.3774 | 0.2212 | 0.0008 | 0.0036 | 0.0069 | 0.0223 | 0.0674 | 0.1032 | 0.0931 | 0.1210 | 0.5817 | 24 | 38 | 60 | 93 | 133 | 183 | 247 | 329 | 451 | 0.0090 | 53.03 | 6.503 | 0.3348 | 70288.5 | 35100000 | 21300000000 | 14900000000000 | 0.4473 | 0.2023 | 0.0513 | 0.0009 | 0.1890 | 0.0115 | 0.2553 | 0.1069 | 0.1609 | 0.1443 | 0.1281 | 0.1866 | 0.0945 | 0.1921 | 0.0604 | 0.1246 | 0.0377 | 0.1011 | 0.0229 | 0.1320 | 0.0004 | 0.0002 | 0.0008 | 0.0006 | 0.0033 | 0.0030 | 0.0171 | 0.0128 | 0.0759 | 0.0579 | 0.1188 | 0.0951 | 0.0890 | 0.0750 | 0.1298 | 0.1102 | 0.5649 | 0.6452 | 0.0008 | 0.0009 | 0.0019 | 0.0028 | 0.0069 | 0.0116 | 0.0329 | 0.0449 | 0.1100 | 0.1226 | 0.1619 | 0.1747 | 0.1106 | 0.1143 | 0.1454 | 0.1490 | 0.4295 | 0.3791 | 0.0003 | 0.0015 | 0.0048 | 0.0246 | 0.0931 | 0.1422 | 0.1029 | 0.1420 | 0.4886 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 933 | 123 | 15895 | 25256 | 160.6 | 49.99 | 222.36 | 201.78 | 108 | 123 | 135 | 145 | 155 | 167 | 180 | 197 | 224 | 0.0522 | 1319 | 1.013 | 68.60 | 26.63 | 1 | 0.0118 | 188 | 0.0011 | 38.56 | 7.182 | 0.2007 | 28277.2 | 5410000 | 1120000000 | 250000000000 | 0.4469 | 0.2019 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0004 | 0.0316 | 0.0036 | 0.1026 | 0.0245 | 0.1744 | 0.0573 | 0.1683 | 0.0626 | 0.1924 | 0.0950 | 0.3207 | 0.7567 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0020 | 0.0001 | 0.0095 | 0.0013 | 0.0356 | 0.0107 | 0.0680 | 0.0249 | 0.0660 | 0.0239 | 0.0986 | 0.0414 | 0.7192 | 0.8976 | 0.0038 | 0.0039 | 0.0105 | 0.0143 | 0.0212 | 0.0306 | 0.0646 | 0.0971 | 0.1280 | 0.1519 | 0.1664 | 0.1956 | 0.1271 | 0.1167 | 0.1414 | 0.1402 | 0.3371 | 0.2497 | 0.0010 | 0.0033 | 0.0088 | 0.0321 | 0.0763 | 0.1269 | 0.1097 | 0.1304 | 0.5115 | 26 | 46 | 75 | 111 | 161 | 221 | 294 | 379 | 507 | 0.0037 | 85.09 | 7.177 | 0.2606 | 90156.2 | 49000000 | 32300000000 | 24700000000000 | 0.5277 | 0.1518 | 0.0405 | 0.0017 | 0.1859 | 0.0114 | 0.2913 | 0.0812 | 0.1595 | 0.1431 | 0.1289 | 0.2051 | 0.0931 | 0.1986 | 0.0540 | 0.1320 | 0.0300 | 0.1078 | 0.0167 | 0.1190 | 0.0003 | 0.0003 | 0.0017 | 0.0005 | 0.0033 | 0.0024 | 0.0137 | 0.0100 | 0.0734 | 0.0561 | 0.1231 | 0.1010 | 0.0947 | 0.0796 | 0.1369 | 0.1199 | 0.5529 | 0.6302 | 0.0009 | 0.0011 | 0.0033 | 0.0060 | 0.0084 | 0.0108 | 0.0290 | 0.0412 | 0.1013 | 0.1114 | 0.1586 | 0.1680 | 0.1119 | 0.1173 | 0.1427 | 0.1435 | 0.4438 | 0.4007 | 0.0005 | 0.0008 | 0.0048 | 0.0220 | 0.0840 | 0.1483 | 0.1014 | 0.1428 | 0.4955 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 120 | 655 | 4898 | 6342 | 156.3 | 38.66 | 125.03 | 113.06 | 113 | 124 | 133 | 141 | 150 | 159 | 170 | 185 | 209 | 0.1042 | 661 | 1.120 | 87.09 | 35.00 | 2 | 0.0484 | 237 | 0.0016 | 33.19 | 6.724 | 0.2162 | 25917.2 | 4580000 | 862000000 | 173000000000 | 0.4020 | 0.2430 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0004 | 0.0371 | 0.0011 | 0.0856 | 0.0217 | 0.1540 | 0.0539 | 0.1540 | 0.0479 | 0.1891 | 0.0811 | 0.3701 | 0.7938 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0144 | 0.0004 | 0.0394 | 0.0127 | 0.0737 | 0.0281 | 0.0709 | 0.0168 | 0.1057 | 0.0388 | 0.6924 | 0.9028 | 0.0088 | 0.0056 | 0.0110 | 0.0056 | 0.0154 | 0.0504 | 0.0647 | 0.1148 | 0.1283 | 0.1961 | 0.1776 | 0.1905 | 0.1217 | 0.0812 | 0.1371 | 0.1204 | 0.3355 | 0.2353 | 0.0014 | 0.0066 | 0.0132 | 0.0448 | 0.0754 | 0.1273 | 0.1056 | 0.1165 | 0.5092 | 23 | 33 | 47 | 65 | 89 | 116 | 152 | 201 | 280 | 0.0060 | 36.94 | 6.174 | 0.3498 | 28413.7 | 9100000 | 3580000000 | 1620000000000 | 0.5069 | 0.1440 | 0.0282 | 0.0015 | 0.0796 | 0.0149 | 0.1823 | 0.0412 | 0.2034 | 0.0865 | 0.1601 | 0.1370 | 0.1511 | 0.1885 | 0.0987 | 0.1555 | 0.0564 | 0.1529 | 0.0403 | 0.2219 | 0.0014 | 0.0006 | 0.0003 | 0.0023 | 0.0061 | 0.0020 | 0.0215 | 0.0159 | 0.0617 | 0.0456 | 0.1159 | 0.0901 | 0.0829 | 0.0697 | 0.1265 | 0.1079 | 0.5837 | 0.6661 | 0.0015 | 0.0031 | 0.0077 | 0.0057 | 0.0113 | 0.0088 | 0.0381 | 0.0453 | 0.0959 | 0.1246 | 0.1562 | 0.1724 | 0.1113 | 0.1089 | 0.1572 | 0.1605 | 0.4206 | 0.3707 | 0.0004 | 0.0033 | 0.0075 | 0.0263 | 0.0889 | 0.1369 | 0.1039 | 0.1507 | 0.4821 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 306 | 371 | 4494 | 4270 | 161.8 | 42.70 | 234.69 | 215.83 | 112 | 124 | 135 | 145 | 156 | 167 | 180 | 196 | 218 | 0.1239 | 529 | 1.009 | 96.75 | 25.96 | 1 | 0.0514 | 231 | 0.0014 | 36.68 | 6.820 | 0.2137 | 28010.0 | 5190000 | 1030000000 | 219000000000 | 0.4291 | 0.2251 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0126 | 0.0000 | 0.0423 | 0.0007 | 0.1057 | 0.0278 | 0.1680 | 0.0566 | 0.1590 | 0.0556 | 0.1745 | 0.0831 | 0.3347 | 0.7761 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0047 | 0.0000 | 0.0109 | 0.0005 | 0.0393 | 0.0157 | 0.0730 | 0.0314 | 0.0659 | 0.0243 | 0.0878 | 0.0444 | 0.7163 | 0.8838 | 0.0022 | 0.0030 | 0.0119 | 0.0211 | 0.0249 | 0.0544 | 0.0692 | 0.0967 | 0.1405 | 0.1601 | 0.1665 | 0.1994 | 0.1373 | 0.0967 | 0.1395 | 0.1178 | 0.3081 | 0.2508 | 0.0005 | 0.0040 | 0.0079 | 0.0287 | 0.0773 | 0.1229 | 0.1145 | 0.1378 | 0.5064 | 19 | 34 | 69 | 122 | 179 | 238 | 316 | 406 | 546 | 0.0057 | 104.66 | 6.818 | 0.2641 | 101650.0 | 57600000 | 38800000000 | 29800000000000 | 0.4229 | 0.2444 | 0.0242 | 0.0057 | 0.1288 | 0.0139 | 0.2254 | 0.0632 | 0.1771 | 0.1165 | 0.1659 | 0.1509 | 0.1385 | 0.1985 | 0.0821 | 0.1600 | 0.0403 | 0.1493 | 0.0177 | 0.1419 | 0.0005 | 0.0004 | 0.0005 | 0.0008 | 0.0063 | 0.0025 | 0.0169 | 0.0144 | 0.0743 | 0.0534 | 0.1139 | 0.0974 | 0.0816 | 0.0732 | 0.1071 | 0.1007 | 0.5989 | 0.6572 | 0.0014 | 0.0016 | 0.0034 | 0.0025 | 0.0096 | 0.0140 | 0.0310 | 0.0404 | 0.0855 | 0.0947 | 0.1365 | 0.1417 | 0.0848 | 0.1046 | 0.1192 | 0.1038 | 0.5286 | 0.4967 | 0.0012 | 0.0040 | 0.0058 | 0.0295 | 0.0728 | 0.1248 | 0.0872 | 0.1092 | 0.5656 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 751 | 267 | 3996 | 13985 | 152.2 | 33.85 | 141.01 | 145.07 | 113 | 124 | 133 | 140 | 148 | 155 | 165 | 178 | 196 | 0.0633 | 885 | 1.001 | 83.55 | 24.08 | 2 | 0.0488 | 195 | 0.0021 | 21.13 | 6.445 | 0.2487 | 24325.1 | 4090000 | 723000000 | 135000000000 | 0.4071 | 0.2421 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0046 | 0.0000 | 0.0217 | 0.0008 | 0.0685 | 0.0210 | 0.1371 | 0.0445 | 0.1470 | 0.0450 | 0.1702 | 0.0623 | 0.4497 | 0.8264 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0072 | 0.0003 | 0.0302 | 0.0141 | 0.0688 | 0.0303 | 0.0676 | 0.0197 | 0.0894 | 0.0351 | 0.7352 | 0.9005 | 0.0015 | 0.0049 | 0.0160 | 0.0099 | 0.0248 | 0.0049 | 0.0758 | 0.1626 | 0.1487 | 0.1576 | 0.1662 | 0.1921 | 0.1122 | 0.1379 | 0.1327 | 0.1281 | 0.3222 | 0.2020 | 0.0033 | 0.0044 | 0.0116 | 0.0311 | 0.0843 | 0.1337 | 0.0943 | 0.1281 | 0.5092 | 19 | 33 | 50 | 68 | 90 | 118 | 157 | 223 | 339 | 0.0069 | 33.28 | 6.213 | 0.3970 | 40926.9 | 17700000 | 9520000000 | 5890000000000 | 0.6594 | 0.0769 | 0.0120 | 0.0022 | 0.0718 | 0.0095 | 0.1486 | 0.0217 | 0.1626 | 0.0638 | 0.1950 | 0.1371 | 0.1406 | 0.1875 | 0.1077 | 0.1501 | 0.0803 | 0.1521 | 0.0813 | 0.2760 | 0.0019 | 0.0005 | 0.0029 | 0.0029 | 0.0075 | 0.0052 | 0.0196 | 0.0142 | 0.0618 | 0.0479 | 0.0945 | 0.0817 | 0.0723 | 0.0641 | 0.1133 | 0.0906 | 0.6263 | 0.6929 | 0.0008 | 0.0003 | 0.0044 | 0.0049 | 0.0072 | 0.0097 | 0.0294 | 0.0346 | 0.0744 | 0.0822 | 0.1224 | 0.1275 | 0.0945 | 0.1005 | 0.1237 | 0.1287 | 0.5430 | 0.5117 | 0.0017 | 0.0042 | 0.0089 | 0.0256 | 0.0701 | 0.1033 | 0.0830 | 0.1114 | 0.5917 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 786 | 723 | 4403 | 10505 | 156.8 | 37.21 | 158.32 | 156.07 | 111 | 125 | 136 | 145 | 154 | 163 | 173 | 187 | 207 | 0.0730 | 767 | 1.082 | 105.15 | 39.01 | 1 | 0.0620 | 273 | 0.0017 | 27.23 | 6.665 | 0.2280 | 25980.4 | 4530000 | 831000000 | 159000000000 | 0.4286 | 0.2358 | 0.0007 | 0.0000 | 0.0045 | 0.0003 | 0.0138 | 0.0018 | 0.0302 | 0.0040 | 0.0832 | 0.0260 | 0.1542 | 0.0510 | 0.1486 | 0.0545 | 0.1725 | 0.0808 | 0.3923 | 0.7817 | 0.0000 | 0.0000 | 0.0009 | 0.0002 | 0.0009 | 0.0002 | 0.0068 | 0.0009 | 0.0392 | 0.0176 | 0.0717 | 0.0309 | 0.0697 | 0.0248 | 0.0958 | 0.0405 | 0.7151 | 0.8849 | 0.0024 | 0.0182 | 0.0155 | 0.0146 | 0.0274 | 0.0474 | 0.0764 | 0.1314 | 0.1372 | 0.1788 | 0.2076 | 0.2336 | 0.1313 | 0.0985 | 0.1396 | 0.1314 | 0.2625 | 0.1460 | 0.0024 | 0.0015 | 0.0068 | 0.0336 | 0.0973 | 0.1357 | 0.1051 | 0.1367 | 0.4810 | 15 | 27 | 45 | 75 | 110 | 150 | 199 | 265 | 380 | 0.0051 | 65.67 | 6.760 | 0.3104 | 49420.1 | 21200000 | 11000000000 | 6460000000000 | 0.5076 | 0.1389 | 0.0172 | 0.0010 | 0.0968 | 0.0078 | 0.2177 | 0.0413 | 0.1765 | 0.0889 | 0.1820 | 0.1633 | 0.1360 | 0.1965 | 0.0859 | 0.1508 | 0.0522 | 0.1403 | 0.0357 | 0.2100 | 0.0006 | 0.0000 | 0.0015 | 0.0009 | 0.0038 | 0.0042 | 0.0125 | 0.0116 | 0.0563 | 0.0446 | 0.0987 | 0.0767 | 0.0747 | 0.0616 | 0.1081 | 0.0892 | 0.6439 | 0.7113 | 0.0009 | 0.0015 | 0.0030 | 0.0036 | 0.0093 | 0.0109 | 0.0246 | 0.0318 | 0.0818 | 0.0982 | 0.1325 | 0.1383 | 0.0971 | 0.0985 | 0.1250 | 0.1438 | 0.5259 | 0.4734 | 0.0002 | 0.0017 | 0.0057 | 0.0214 | 0.0664 | 0.1176 | 0.0927 | 0.1161 | 0.5782 | |||
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 502 | 891 | 697 | 2813 | 320.4 | 207.81 | 13.17 | 5.09 | 98 | 125 | 170 | 212 | 264 | 326 | 402 | 514 | 669 | 0.1337 | 376 | 1.160 | 26.25 | 8.00 | 2 | 0.0918 | 64 | 0.0019 | 99.20 | 6.369 | 0.1311 | 145754.0 | 81100000 | 50300000000 | 33200000000000 | 0.2968 | 0.3295 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0303 | 0.0000 | 0.0909 | 0.0036 | 0.2348 | 0.1155 | 0.2348 | 0.1769 | 0.2273 | 0.1227 | 0.1288 | 0.1444 | 0.0530 | 0.4368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0084 | 0.0022 | 0.0503 | 0.0508 | 0.0670 | 0.0640 | 0.0475 | 0.0375 | 0.0587 | 0.0486 | 0.7682 | 0.7969 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0114 | 0.0487 | 0.0739 | 0.1062 | 0.0966 | 0.0442 | 0.0568 | 0.0752 | 0.0852 | 0.7124 | 0.6761 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0565 | 0.0919 | 0.0389 | 0.0671 | 0.7420 | 7 | 9 | 10 | 12 | 13 | 14 | 15 | 17 | 20 | 0.4201 | 0.26 | 1.281 | 0.8672 | 199.4 | 3414.53 | 65866.6 | 1430000 | 0.5670 | 0.1264 | 0.0375 | 0.0039 | 0.0586 | 0.0218 | 0.0980 | 0.0262 | 0.1548 | 0.0510 | 0.1951 | 0.0694 | 0.2070 | 0.0879 | 0.1712 | 0.1422 | 0.0678 | 0.2146 | 0.0101 | 0.3830 | 0.0136 | 0.0020 | 0.0172 | 0.0131 | 0.0183 | 0.0127 | 0.0365 | 0.0295 | 0.0662 | 0.0516 | 0.0986 | 0.0540 | 0.1377 | 0.0704 | 0.2165 | 0.1101 | 0.3954 | 0.6566 | 0.0545 | 0.0966 | 0.0703 | 0.0914 | 0.0812 | 0.0914 | 0.1018 | 0.1227 | 0.1115 | 0.1488 | 0.1236 | 0.1488 | 0.1164 | 0.1175 | 0.1794 | 0.1071 | 0.1612 | 0.0757 | 0.0122 | 0.0278 | 0.0523 | 0.0733 | 0.1025 | 0.1263 | 0.1514 | 0.1826 | 0.2716 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 209 | 861 | 543 | 4357 | 152.9 | 32.22 | 90.49 | 146.81 | 112 | 125 | 134 | 144 | 152 | 161 | 170 | 181 | 194 | 0.0925 | 403 | 1.074 | 82.81 | 25.61 | 1 | 0.3665 | 199 | 0.0040 | 21.07 | 5.680 | 0.2454 | 24410.0 | 4050000 | 697000000 | 124000000000 | 0.4295 | 0.2088 | 0.0000 | 0.0000 | 0.0029 | 0.0000 | 0.0029 | 0.0000 | 0.0632 | 0.0078 | 0.1523 | 0.0447 | 0.1638 | 0.0953 | 0.1868 | 0.0700 | 0.1782 | 0.1498 | 0.2500 | 0.6323 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0075 | 0.0690 | 0.0413 | 0.0980 | 0.0732 | 0.0802 | 0.0450 | 0.1114 | 0.0994 | 0.6236 | 0.7336 | 0.0198 | 0.0000 | 0.0099 | 0.0000 | 0.0891 | 0.1053 | 0.1089 | 0.3684 | 0.1782 | 0.3684 | 0.1188 | 0.0526 | 0.1584 | 0.1053 | 0.1386 | 0.0000 | 0.1782 | 0.0000 | 0.0000 | 0.0075 | 0.0491 | 0.0340 | 0.1132 | 0.1208 | 0.1094 | 0.1245 | 0.4415 | 6 | 7 | 9 | 10 | 12 | 26 | 64 | 155 | 335 | 0.1505 | 5.85 | 3.608 | 0.6197 | 29737.3 | 12900000 | 6260000000 | 3270000000000 | 0.5075 | 0.1310 | 0.0714 | 0.0045 | 0.1939 | 0.0201 | 0.2041 | 0.0447 | 0.2857 | 0.1029 | 0.1276 | 0.2282 | 0.0867 | 0.2371 | 0.0255 | 0.1365 | 0.0051 | 0.1275 | 0.0000 | 0.0984 | 0.0016 | 0.0014 | 0.0008 | 0.0000 | 0.0016 | 0.0007 | 0.0195 | 0.0114 | 0.0568 | 0.0549 | 0.0860 | 0.0834 | 0.0543 | 0.0499 | 0.0933 | 0.0848 | 0.6861 | 0.7135 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0031 | 0.0145 | 0.0157 | 0.0685 | 0.0680 | 0.0858 | 0.0931 | 0.0559 | 0.0596 | 0.1022 | 0.1004 | 0.6702 | 0.6600 | 0.0009 | 0.0000 | 0.0027 | 0.0089 | 0.0608 | 0.0956 | 0.0536 | 0.0903 | 0.6872 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1078 | 76 | 3929 | 6047 | 161.4 | 44.19 | 132.87 | 179.68 | 115 | 126 | 135 | 144 | 153 | 164 | 177 | 192 | 220 | 0.1057 | 639 | 1.011 | 168.43 | 62.07 | 1 | 0.1168 | 459 | 0.0015 | 39.33 | 6.819 | 0.1959 | 28002.9 | 5250000 | 1070000000 | 240000000000 | 0.4412 | 0.2076 | 0.0013 | 0.0000 | 0.0035 | 0.0003 | 0.0083 | 0.0017 | 0.0372 | 0.0034 | 0.0959 | 0.0278 | 0.1713 | 0.0613 | 0.1827 | 0.0573 | 0.1866 | 0.0994 | 0.3132 | 0.7487 | 0.0010 | 0.0000 | 0.0007 | 0.0003 | 0.0023 | 0.0003 | 0.0128 | 0.0000 | 0.0437 | 0.0177 | 0.0801 | 0.0303 | 0.0782 | 0.0230 | 0.1120 | 0.0483 | 0.6693 | 0.8803 | 0.0066 | 0.0058 | 0.0092 | 0.0203 | 0.0328 | 0.0407 | 0.0814 | 0.0872 | 0.1273 | 0.1802 | 0.1654 | 0.2122 | 0.1247 | 0.1105 | 0.1535 | 0.1337 | 0.2992 | 0.2093 | 0.0035 | 0.0035 | 0.0106 | 0.0388 | 0.1052 | 0.1240 | 0.1217 | 0.1499 | 0.4427 | 9 | 12 | 16 | 25 | 49 | 95 | 150 | 233 | 366 | 0.0201 | 68.11 | 5.908 | 0.3842 | 49932.6 | 27200000 | 17800000000 | 13000000000000 | 0.5438 | 0.1149 | 0.0657 | 0.0029 | 0.2044 | 0.0115 | 0.2117 | 0.1319 | 0.1387 | 0.1616 | 0.1515 | 0.2122 | 0.0985 | 0.1539 | 0.0511 | 0.1023 | 0.0547 | 0.0918 | 0.0237 | 0.1319 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0009 | 0.0031 | 0.0234 | 0.0147 | 0.0661 | 0.0570 | 0.0974 | 0.0892 | 0.0793 | 0.0694 | 0.1058 | 0.0927 | 0.6249 | 0.6735 | 0.0017 | 0.0007 | 0.0006 | 0.0000 | 0.0076 | 0.0046 | 0.0285 | 0.0359 | 0.0802 | 0.0894 | 0.1197 | 0.1305 | 0.0953 | 0.0868 | 0.1104 | 0.1194 | 0.5561 | 0.5329 | 0.0010 | 0.0030 | 0.0081 | 0.0186 | 0.0756 | 0.1149 | 0.0832 | 0.1144 | 0.5811 | |||
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 |