High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 387 | 433 | 5231 | 10050 | 128.6 | 29.95 | 253.02 | 164.61 | 95 | 106 | 112 | 118 | 124 | 131 | 139 | 149 | 167 | 0.0766 | 770 | 1.025 | 94.58 | 21.95 | 1 | 0.0417 | 218 | 0.0027 | 19.06 | 6.270 | 0.2625 | 17434.3 | 2500000 | 381000000 | 61800000000 | 0.4642 | 0.1924 | 0.0009 | 0.0000 | 0.0012 | 0.0004 | 0.0063 | 0.0008 | 0.0155 | 0.0006 | 0.0748 | 0.0204 | 0.1327 | 0.0433 | 0.1376 | 0.0474 | 0.1804 | 0.0775 | 0.4506 | 0.8094 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0004 | 0.0058 | 0.0004 | 0.0353 | 0.0138 | 0.0679 | 0.0272 | 0.0616 | 0.0216 | 0.0981 | 0.0325 | 0.7281 | 0.9042 | 0.0035 | 0.0236 | 0.0058 | 0.0505 | 0.0256 | 0.0337 | 0.0816 | 0.0741 | 0.1457 | 0.1886 | 0.1620 | 0.1818 | 0.1550 | 0.0976 | 0.1352 | 0.1515 | 0.2855 | 0.1987 | 0.0022 | 0.0065 | 0.0113 | 0.0427 | 0.0946 | 0.1325 | 0.1176 | 0.1451 | 0.4475 | 60 | 102 | 143 | 183 | 224 | 272 | 324 | 390 | 488 | 0.0010 | 93.19 | 7.522 | 0.1835 | 91109.9 | 40300000 | 20400000000 | 11500000000000 | 0.4846 | 0.1715 | 0.0159 | 0.0002 | 0.0785 | 0.0058 | 0.2247 | 0.0267 | 0.1565 | 0.0755 | 0.1770 | 0.1506 | 0.1499 | 0.1952 | 0.0887 | 0.1576 | 0.0612 | 0.1601 | 0.0476 | 0.2282 | 0.0009 | 0.0000 | 0.0011 | 0.0015 | 0.0050 | 0.0019 | 0.0179 | 0.0119 | 0.0651 | 0.0482 | 0.1005 | 0.0787 | 0.0938 | 0.0705 | 0.1206 | 0.1004 | 0.5951 | 0.6868 | 0.0012 | 0.0036 | 0.0041 | 0.0052 | 0.0106 | 0.0203 | 0.0361 | 0.0584 | 0.0993 | 0.1247 | 0.1704 | 0.1918 | 0.1202 | 0.1275 | 0.1539 | 0.1485 | 0.4042 | 0.3201 | 0.0002 | 0.0034 | 0.0073 | 0.0241 | 0.0768 | 0.1375 | 0.1128 | 0.1355 | 0.5024 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 659 | 414 | 3454 | 6251 | 174.4 | 39.87 | 242.89 | 154.32 | 131 | 143 | 152 | 159 | 167 | 177 | 189 | 204 | 226 | 0.1125 | 703 | 1.107 | 91.24 | 26.63 | 1 | 0.0617 | 213 | 0.0019 | 25.62 | 6.561 | 0.2385 | 32018.5 | 6210000 | 1280000000 | 278000000000 | 0.4520 | 0.2052 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0088 | 0.0006 | 0.0206 | 0.0022 | 0.0697 | 0.0235 | 0.1434 | 0.0423 | 0.1298 | 0.0346 | 0.1684 | 0.0676 | 0.4579 | 0.8289 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0003 | 0.0052 | 0.0003 | 0.0351 | 0.0160 | 0.0762 | 0.0274 | 0.0616 | 0.0189 | 0.1043 | 0.0335 | 0.7155 | 0.9036 | 0.0017 | 0.0154 | 0.0134 | 0.0205 | 0.0185 | 0.0308 | 0.0487 | 0.1026 | 0.1546 | 0.1231 | 0.1748 | 0.1846 | 0.1294 | 0.1538 | 0.1429 | 0.0923 | 0.3160 | 0.2769 | 0.0007 | 0.0033 | 0.0080 | 0.0361 | 0.0916 | 0.1424 | 0.0989 | 0.1404 | 0.4786 | 79 | 111 | 142 | 170 | 206 | 251 | 299 | 360 | 457 | 0.0013 | 68.96 | 7.135 | 0.2323 | 82803.2 | 35900000 | 18500000000 | 10900000000000 | 0.5283 | 0.1292 | 0.0088 | 0.0007 | 0.0739 | 0.0045 | 0.1684 | 0.0182 | 0.1611 | 0.0636 | 0.1859 | 0.1374 | 0.1720 | 0.2049 | 0.1061 | 0.1528 | 0.0820 | 0.1545 | 0.0417 | 0.2633 | 0.0003 | 0.0002 | 0.0027 | 0.0005 | 0.0066 | 0.0040 | 0.0217 | 0.0160 | 0.0714 | 0.0488 | 0.1042 | 0.0905 | 0.0819 | 0.0726 | 0.1153 | 0.1014 | 0.5959 | 0.6660 | 0.0041 | 0.0042 | 0.0051 | 0.0035 | 0.0128 | 0.0229 | 0.0389 | 0.0660 | 0.1064 | 0.1313 | 0.1529 | 0.1771 | 0.1233 | 0.1188 | 0.1483 | 0.1465 | 0.4082 | 0.3299 | 0.0004 | 0.0031 | 0.0100 | 0.0268 | 0.0824 | 0.1234 | 0.1031 | 0.1388 | 0.5121 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 284 | 132 | 3587 | 822 | 127.8 | 29.04 | 269.41 | 172.52 | 95 | 103 | 110 | 116 | 124 | 131 | 139 | 150 | 166 | 0.4538 | 373 | 0.730 | 52.80 | 16.97 | 1 | 0.0435 | 156 | 0.0026 | 19.75 | 6.264 | 0.2480 | 17172.9 | 2430000 | 364000000 | 57600000000 | 0.4499 | 0.2003 | 0.0013 | 0.0000 | 0.0039 | 0.0000 | 0.0057 | 0.0006 | 0.0284 | 0.0024 | 0.0900 | 0.0181 | 0.1429 | 0.0404 | 0.1608 | 0.0440 | 0.2172 | 0.0871 | 0.3497 | 0.8073 | 0.0007 | 0.0000 | 0.0031 | 0.0000 | 0.0021 | 0.0000 | 0.0106 | 0.0011 | 0.0398 | 0.0118 | 0.0621 | 0.0230 | 0.0648 | 0.0149 | 0.1204 | 0.0342 | 0.6964 | 0.9150 | 0.0048 | 0.0197 | 0.0207 | 0.0542 | 0.0287 | 0.0690 | 0.0813 | 0.1232 | 0.1643 | 0.1675 | 0.1978 | 0.1773 | 0.1372 | 0.1330 | 0.1547 | 0.1182 | 0.2105 | 0.1379 | 0.0025 | 0.0044 | 0.0176 | 0.0478 | 0.0806 | 0.1233 | 0.1296 | 0.1517 | 0.4424 | 69 | 114 | 153 | 190 | 229 | 286 | 352 | 427 | 520 | 0.0018 | 138.36 | 6.442 | 0.1434 | 102307.0 | 47200000 | 24500000000 | 13800000000000 | 0.3578 | 0.2281 | 0.0612 | 0.0059 | 0.2245 | 0.0413 | 0.3197 | 0.1150 | 0.1905 | 0.1475 | 0.1020 | 0.2448 | 0.0748 | 0.2035 | 0.0136 | 0.1091 | 0.0136 | 0.0973 | 0.0000 | 0.0354 | 0.0023 | 0.0018 | 0.0093 | 0.0161 | 0.0395 | 0.0233 | 0.0302 | 0.0376 | 0.1674 | 0.1485 | 0.2256 | 0.2093 | 0.1605 | 0.1503 | 0.1581 | 0.1807 | 0.2070 | 0.2326 | 0.0000 | 0.0045 | 0.0071 | 0.0227 | 0.0247 | 0.0455 | 0.0813 | 0.0818 | 0.2226 | 0.2682 | 0.2438 | 0.2182 | 0.1696 | 0.1591 | 0.1060 | 0.0682 | 0.1449 | 0.1318 | 0.0029 | 0.0086 | 0.0173 | 0.0490 | 0.1844 | 0.2478 | 0.1729 | 0.1499 | 0.1671 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 | |
Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1249 | 243 | 482 | 1741 | 112.1 | 48.48 | 496.07 | 386.37 | 42 | 60 | 88 | 106 | 116 | 127 | 137 | 153 | 174 | 0.1499 | 261 | 1.058 | 86.21 | 27.78 | 3 | 0.4502 | 217 | 0.0029 | 40.32 | 5.929 | 0.1866 | 14918.8 | 2200000 | 349000000 | 58500000000 | 0.3329 | 0.2700 | 0.0000 | 0.0000 | 0.0174 | 0.0000 | 0.0407 | 0.0035 | 0.2035 | 0.0213 | 0.1512 | 0.0922 | 0.1453 | 0.1844 | 0.0988 | 0.0851 | 0.1337 | 0.1418 | 0.2093 | 0.4716 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0027 | 0.0453 | 0.0461 | 0.0937 | 0.0867 | 0.0423 | 0.0298 | 0.0816 | 0.0569 | 0.7311 | 0.7778 | 0.0000 | 0.0115 | 0.0063 | 0.0000 | 0.0252 | 0.0115 | 0.0566 | 0.0575 | 0.1195 | 0.1379 | 0.1258 | 0.1954 | 0.1447 | 0.0920 | 0.1132 | 0.2069 | 0.4088 | 0.2874 | 0.0000 | 0.0000 | 0.0000 | 0.0150 | 0.0789 | 0.1353 | 0.0714 | 0.1504 | 0.5489 | 91 | 159 | 229 | 321 | 421 | 515 | 623 | 761 | 1010 | 0.0012 | 148.81 | 7.039 | 0.1568 | 395283.0 | 416000000 | 525000000000 | 746000000000000 | 0.4447 | 0.2259 | 0.0146 | 0.0059 | 0.0700 | 0.0089 | 0.2012 | 0.0178 | 0.2128 | 0.0624 | 0.1399 | 0.1516 | 0.1808 | 0.2184 | 0.0845 | 0.1798 | 0.0379 | 0.1590 | 0.0583 | 0.1961 | 0.0000 | 0.0018 | 0.0022 | 0.0037 | 0.0132 | 0.0055 | 0.0209 | 0.0193 | 0.0801 | 0.0644 | 0.1207 | 0.1030 | 0.0955 | 0.0828 | 0.1273 | 0.1122 | 0.5401 | 0.6072 | 0.0000 | 0.0048 | 0.0035 | 0.0121 | 0.0141 | 0.0266 | 0.0493 | 0.0725 | 0.1303 | 0.1401 | 0.1708 | 0.1715 | 0.1338 | 0.1232 | 0.1549 | 0.1014 | 0.3433 | 0.3478 | 0.0014 | 0.0014 | 0.0149 | 0.0408 | 0.0883 | 0.1386 | 0.1264 | 0.1522 | 0.4361 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 321 | 840 | 426 | 368 | 95.5 | 47.70 | 697.86 | 488.70 | 32 | 42 | 60 | 77 | 96 | 112 | 127 | 143 | 162 | 0.4701 | 173 | 0.664 | 93.61 | 19.80 | 1 | 0.5915 | 252 | 0.0030 | 67.57 | 5.878 | 0.1356 | 11384.7 | 1540000 | 222000000 | 33700000000 | 0.2891 | 0.3236 | 0.0000 | 0.0000 | 0.0000 | 0.0052 | 0.1616 | 0.0000 | 0.1919 | 0.0155 | 0.2121 | 0.1503 | 0.1515 | 0.2591 | 0.2020 | 0.1295 | 0.0404 | 0.1969 | 0.0404 | 0.2435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0032 | 0.0575 | 0.0583 | 0.0996 | 0.0841 | 0.0421 | 0.0388 | 0.0613 | 0.0680 | 0.7318 | 0.7476 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0247 | 0.0517 | 0.0802 | 0.0862 | 0.1049 | 0.1897 | 0.0988 | 0.1207 | 0.1420 | 0.1034 | 0.5432 | 0.4483 | 0.0000 | 0.0000 | 0.0000 | 0.0140 | 0.0698 | 0.0930 | 0.0512 | 0.0884 | 0.6837 | 135 | 270 | 399 | 510 | 616 | 717 | 852 | 1036 | 1456 | 0.0038 | 170.10 | 5.726 | 0.1849 | 725176.0 | 955000000 | 1470000000000 | 2.5E+15 | 0.4289 | 0.2015 | 0.0465 | 0.0000 | 0.1860 | 0.0120 | 0.2558 | 0.0663 | 0.1279 | 0.1205 | 0.1047 | 0.2651 | 0.1395 | 0.2108 | 0.0814 | 0.1566 | 0.0581 | 0.0904 | 0.0000 | 0.0783 | 0.0050 | 0.0000 | 0.0300 | 0.0000 | 0.0550 | 0.0405 | 0.0750 | 0.0526 | 0.1250 | 0.1579 | 0.1600 | 0.1741 | 0.1700 | 0.1660 | 0.1450 | 0.1296 | 0.2350 | 0.2794 | 0.0439 | 0.0000 | 0.0351 | 0.0000 | 0.0263 | 0.0864 | 0.1228 | 0.0864 | 0.1053 | 0.1605 | 0.2193 | 0.1235 | 0.0965 | 0.1111 | 0.0965 | 0.1358 | 0.2544 | 0.2963 | 0.0132 | 0.0395 | 0.0724 | 0.0921 | 0.1645 | 0.1579 | 0.1382 | 0.0921 | 0.2303 | |
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 271 | 847 | 908 | 1431 | 91.8 | 33.70 | 687.44 | 391.20 | 43 | 63 | 77 | 87 | 93 | 101 | 107 | 116 | 134 | 0.2628 | 376 | 0.421 | 172.41 | 28.64 | 1 | 0.6244 | 567 | 0.0021 | 37.97 | 6.338 | 0.1970 | 9567.4 | 1090000 | 135000000 | 17800000000 | 0.3571 | 0.2522 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0114 | 0.0030 | 0.0571 | 0.0091 | 0.1393 | 0.0619 | 0.1963 | 0.0937 | 0.1667 | 0.0967 | 0.1758 | 0.1450 | 0.2534 | 0.5906 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0064 | 0.0538 | 0.0412 | 0.0837 | 0.0528 | 0.0658 | 0.0528 | 0.1046 | 0.0670 | 0.6861 | 0.7796 | 0.0087 | 0.0175 | 0.0000 | 0.0000 | 0.0087 | 0.0263 | 0.0563 | 0.0614 | 0.1255 | 0.1228 | 0.1558 | 0.1228 | 0.1169 | 0.0877 | 0.1169 | 0.1667 | 0.4113 | 0.3947 | 0.0000 | 0.0000 | 0.0083 | 0.0188 | 0.0708 | 0.1188 | 0.0792 | 0.1125 | 0.5917 | 182 | 286 | 422 | 565 | 661 | 778 | 882 | 1021 | 1232 | 0.0013 | 104.63 | 6.818 | 0.1663 | 625506.0 | 665000000 | 783000000000 | 994000000000000 | 0.4941 | 0.1384 | 0.0138 | 0.0030 | 0.0801 | 0.0120 | 0.1713 | 0.0360 | 0.1685 | 0.0810 | 0.2293 | 0.1589 | 0.1547 | 0.1799 | 0.1105 | 0.1664 | 0.0497 | 0.1709 | 0.0221 | 0.1919 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0148 | 0.0050 | 0.0319 | 0.0308 | 0.1105 | 0.0876 | 0.1390 | 0.1194 | 0.1378 | 0.1095 | 0.1412 | 0.1443 | 0.4226 | 0.5035 | 0.0019 | 0.0030 | 0.0233 | 0.0296 | 0.0233 | 0.0266 | 0.0698 | 0.1272 | 0.1550 | 0.1775 | 0.1609 | 0.2160 | 0.1453 | 0.1183 | 0.1221 | 0.1124 | 0.2985 | 0.1893 | 0.0000 | 0.0116 | 0.0217 | 0.0564 | 0.1302 | 0.1664 | 0.1230 | 0.1302 | 0.3603 | |
Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |