High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 149 240 image if available 6671 12334 390.0 50.74 109.56 270.04 317 352 374 389 399 409 419 431 446 0.0712 878 0.700 125.40 29.61 3 0.0475 317 0.0019 22.81 6.624 0.2349 154695.0
62200000
25300000000
10400000000000
0.4580 0.1948 0.0000 0.0000 0.0002 0.0000 0.0010 0.0000 0.0037 0.0003 0.0169 0.0112 0.0407 0.0210 0.0412 0.0134 0.0715 0.0187 0.8249 0.9354 0.0000 0.0000 0.0000 0.0000 0.0005 0.0000 0.0023 0.0003 0.0133 0.0112 0.0316 0.0210 0.0235 0.0134 0.0319 0.0187 0.8969 0.9354 0.1176 0.0000 0.1438 0.0000 0.1373 0.0000 0.1830 0.0000 0.1111 0.0000 0.1569 0.0000 0.0261 0.0000 0.0523 0.0000 0.0719 0.0000 0.0020 0.0033 0.0091 0.0202 0.0463 0.0663 0.0825 0.1189 0.6514 9 11 12 14 15 18 24 59 344 0.2142 6.81 2.736 0.6641 84919.1
101000000
144000000000
229000000000000
0.5929 0.1077 0.0204 0.0068 0.0980 0.0068 0.1592 0.0492 0.1878 0.0881 0.2082 0.1593 0.1755 0.1864 0.1020 0.1203 0.0367 0.1661 0.0122 0.2169 0.0005 0.0017 0.0019 0.0004 0.0014 0.0034 0.0052 0.0085 0.0331 0.0296 0.0553 0.0525 0.0355 0.0407 0.0766 0.0805 0.7905 0.7827 0.0000 0.0000 0.0000 0.0006 0.0021 0.0017 0.0064 0.0079 0.0380 0.0350 0.0545 0.0599 0.0401 0.0418 0.0866 0.0870 0.7722 0.7662 0.0000 0.0000 0.0020 0.0076 0.0289 0.0613 0.0370 0.0770 0.7863
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 305 753 image if available 14531 31502 446.4 61.03 117.13 162.48 365 402 424 439 452 464 476 491 515 0.0488 1538 0.844 110.02 27.80 4 0.0189 274 0.0017 18.96 6.823 0.2707 202963.0
93800000
44000000000
21000000000000
0.4307 0.2135 0.0003 0.0001 0.0001 0.0000 0.0009 0.0000 0.0036 0.0001 0.0149 0.0077 0.0284 0.0166 0.0253 0.0080 0.0383 0.0128 0.8882 0.9547 0.0001 0.0001 0.0000 0.0000 0.0000 0.0000 0.0019 0.0001 0.0098 0.0077 0.0186 0.0166 0.0149 0.0080 0.0188 0.0117 0.9360 0.9558 0.0148 1.0000 0.0239 0.0000 0.0091 0.0000 0.0262 0.0000 0.0809 0.0000 0.0945 0.0000 0.0809 0.0000 0.1173 0.0000 0.5524 0.0000 0.0022 0.0070 0.0123 0.0187 0.0346 0.0523 0.0642 0.0921 0.7167 13 16 21 33 52 79 118 180 305 0.0400 19.55 4.937 0.5597 40119.5
22800000
16800000000
14600000000000
0.4801 0.1897 0.0180 0.0019 0.0684 0.0102 0.1417 0.0304 0.1389 0.0605 0.1660 0.1385 0.1648 0.1775 0.1107 0.1263 0.1041 0.1394 0.0873 0.3154 0.0012 0.0003 0.0022 0.0020 0.0034 0.0030 0.0115 0.0124 0.0463 0.0387 0.0745 0.0614 0.0495 0.0472 0.0766 0.0656 0.7348 0.7694 0.0005 0.0007 0.0024 0.0020 0.0066 0.0068 0.0187 0.0217 0.0585 0.0622 0.0953 0.1084 0.0633 0.0699 0.0954 0.0979 0.6595 0.6304 0.0004 0.0017 0.0044 0.0151 0.0498 0.0888 0.0599 0.0831 0.6968
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 673 661 image if available 8356 21692 629.4 88.97 157.77 200.04 505 558 588 612 637 660 678 703 736 0.0423 917 1.088 108.30 37.05 1 0.0333 278 0.0009 30.54 7.337 0.2196 404042.0
264000000
175000000000
118000000000000
0.4222 0.2219 0.0003 0.0000 0.0004 0.0000 0.0007 0.0000 0.0036 0.0002 0.0168 0.0091 0.0339 0.0170 0.0309 0.0087 0.0431 0.0141 0.8703 0.9508 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0017 0.0002 0.0097 0.0091 0.0211 0.0170 0.0174 0.0087 0.0212 0.0141 0.9286 0.9508 0.0052 0.0000 0.0087 0.0000 0.0280 0.0000 0.0332 0.0000 0.0769 0.0000 0.1206 0.0000 0.0962 0.0000 0.1521 0.0000 0.4790 0.0000 0.0011 0.0031 0.0058 0.0105 0.0285 0.0524 0.0515 0.0731 0.7740 10 13 19 33 63 113 189 289 461 0.0633 29.43 5.277 0.5302 64906.9
36700000
24600000000
18400000000000
0.4278 0.2001 0.0270 0.0020 0.1224 0.0151 0.2282 0.0660 0.1787 0.1115 0.1483 0.1596 0.1201 0.2156 0.0684 0.1388 0.0615 0.1073 0.0454 0.1841 0.0001 0.0003 0.0002 0.0008 0.0015 0.0014 0.0077 0.0098 0.0437 0.0330 0.0678 0.0540 0.0479 0.0450 0.0793 0.0589 0.7519 0.7967 0.0005 0.0000 0.0015 0.0012 0.0026 0.0031 0.0122 0.0151 0.0611 0.0727 0.0953 0.1124 0.0662 0.0769 0.1035 0.1141 0.6570 0.6045 0.0001 0.0010 0.0024 0.0121 0.0486 0.0835 0.0554 0.0881 0.7087
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 561 247 image if available 4445 15033 466.1 65.09 63.62 138.06 379 413 433 450 466 481 499 521 551 0.0559 840 1.186 46.40 17.49 1 0.0270 120 0.0015 34.76 6.820 0.2169 221513.0
107000000
52800000000
26400000000000
0.4116 0.2311 0.0000 0.0000 0.0000 0.0000 0.0011 0.0000 0.0035 0.0002 0.0355 0.0137 0.0646 0.0248 0.0635 0.0142 0.0910 0.0205 0.7407 0.9266 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0020 0.0002 0.0221 0.0137 0.0368 0.0248 0.0314 0.0142 0.0456 0.0187 0.8620 0.9284 0.0110 1.0000 0.0192 0.0000 0.0219 0.0000 0.0959 0.0000 0.1479 0.0000 0.1726 0.0000 0.1397 0.0000 0.1288 0.0000 0.2630 0.0000 0.0004 0.0036 0.0085 0.0278 0.0732 0.0996 0.0961 0.1302 0.5606 7 8 9 10 12 15 22 57 200 0.2619 11.61 3.053 0.7574 23105.5
14100000
11000000000
10100000000000
0.4691 0.1844 0.0363 0.0081 0.0726 0.0208 0.0726 0.0728 0.1501 0.0786 0.1622 0.1110 0.1671 0.1260 0.1574 0.1191 0.1090 0.1445 0.0726 0.3191 0.0003 0.0012 0.0013 0.0030 0.0023 0.0044 0.0077 0.0094 0.0229 0.0195 0.0265 0.0301 0.0245 0.0248 0.0368 0.0387 0.8777 0.8689 0.0011 0.0000 0.0011 0.0004 0.0022 0.0024 0.0108 0.0091 0.0238 0.0234 0.0309 0.0313 0.0313 0.0317 0.0395 0.0527 0.8593 0.8490 0.0003 0.0007 0.0048 0.0104 0.0214 0.0308 0.0235 0.0443 0.8637
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 457 212 image if available 6322 18147 382.8 44.78 238.77 294.82 326 348 362 373 384 395 406 419 439 0.0600 1088 1.215 99.36 36.50 1 0.0386 244 0.0018 29.68 6.658 0.2214 148564.0
58400000
23200000000
9350000000000
0.4200 0.2268 0.0000 0.0000 0.0004 0.0000 0.0005 0.0000 0.0033 0.0005 0.0198 0.0108 0.0385 0.0209 0.0480 0.0104 0.0811 0.0223 0.8084 0.9351 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0015 0.0005 0.0136 0.0108 0.0260 0.0209 0.0246 0.0104 0.0395 0.0223 0.8947 0.9351 0.0536 0.0000 0.0421 0.0000 0.0651 0.0000 0.1303 0.0000 0.1418 0.0000 0.2222 0.0000 0.1188 0.0000 0.1341 0.0000 0.0920 0.0000 0.0012 0.0049 0.0132 0.0292 0.0679 0.1075 0.1161 0.1588 0.5012 17 22 29 46 89 180 301 457 675 0.0295 57.83 5.943 0.4328 143927.0
117000000
112000000000
121000000000000
0.4463 0.1845 0.0546 0.0038 0.1914 0.0093 0.2906 0.1053 0.1701 0.1693 0.1184 0.2109 0.1042 0.1922 0.0475 0.1153 0.0156 0.0952 0.0078 0.0987 0.0001 0.0005 0.0011 0.0005 0.0034 0.0014 0.0108 0.0082 0.0532 0.0501 0.0872 0.0742 0.0606 0.0519 0.0872 0.0802 0.6963 0.7330 0.0005 0.0004 0.0021 0.0008 0.0042 0.0052 0.0150 0.0185 0.0656 0.0707 0.1028 0.1137 0.0807 0.0882 0.1081 0.1140 0.6208 0.5885 0.0002 0.0016 0.0046 0.0142 0.0602 0.0943 0.0678 0.0986 0.6586
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 199 260 image if available 10686 24087 343.1 42.34 218.62 243.80 294 309 319 329 339 349 361 376 398 0.0560 1348 1.108 80.65 27.02 2 0.0188 201 0.0020 20.94 6.553 0.2495 119532.0
42300000
15200000000
5550000000000
0.4430 0.2105 0.0001 0.0000 0.0002 0.0000 0.0012 0.0000 0.0032 0.0005 0.0194 0.0089 0.0355 0.0176 0.0461 0.0113 0.0755 0.0211 0.8188 0.9407 0.0000 0.0000 0.0000 0.0000 0.0001 0.0000 0.0015 0.0000 0.0114 0.0086 0.0212 0.0159 0.0232 0.0077 0.0352 0.0146 0.9074 0.9532 0.0199 0.0000 0.0385 0.0000 0.0442 0.0000 0.0855 0.0000 0.0954 0.0000 0.1311 0.0000 0.1197 0.0000 0.1211 0.0000 0.3447 0.0000 0.0047 0.0098 0.0155 0.0422 0.0674 0.0986 0.1131 0.1277 0.5211 18 23 29 46 110 198 297 422 589 0.0307 46.12 5.951 0.4302 107227.0
68300000
50200000000
40800000000000
0.5298 0.1259 0.0245 0.0018 0.1127 0.0149 0.2277 0.0610 0.1750 0.0972 0.1550 0.1809 0.1245 0.2068 0.0732 0.1277 0.0609 0.1204 0.0464 0.1894 0.0000 0.0000 0.0005 0.0002 0.0017 0.0016 0.0077 0.0073 0.0415 0.0338 0.0707 0.0588 0.0495 0.0417 0.0772 0.0625 0.7513 0.7941 0.0004 0.0004 0.0010 0.0016 0.0029 0.0041 0.0139 0.0205 0.0578 0.0653 0.0903 0.1105 0.0763 0.0890 0.1087 0.1110 0.6487 0.5975 0.0001 0.0011 0.0034 0.0105 0.0471 0.0826 0.0615 0.0887 0.7050
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 765 448 image if available 1036 4704 600.2 210.48 6.20 1.84 332 391 444 509 577 659 743 818 904 0.0897 422 1.225 53.31 21.95 1 0.1332 138 0.0016 24.08 6.554 0.2404 404516.0
298000000
234000000000
192000000000000
0.3419 0.2894 0.0000 0.0000 0.0000 0.0000 0.0000 0.0014 0.0031 0.0043 0.1242 0.0558 0.2329 0.1016 0.1304 0.0629 0.1739 0.0801 0.3354 0.6938 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0011 0.0392 0.0339 0.0633 0.0532 0.0271 0.0271 0.0542 0.0407 0.8163 0.8439 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0058 0.0324 0.0585 0.0649 0.0848 0.1135 0.0409 0.0757 0.0673 0.0811 0.7427 0.6324 0.0000 0.0000 0.0021 0.0062 0.0374 0.0811 0.0395 0.0457 0.7879 4 5 5 6 6 7 7 8 8 0.0274 6.20 3.980 0.3875 41.8
302.145
2320.55
18932.6
0.4537 0.1856 0.0023 0.0005 0.0113 0.0013 0.0441 0.0090 0.1027 0.0249 0.1782 0.0542 0.2398 0.1111 0.2262 0.2325 0.1613 0.3262 0.0341 0.2402 0.0000 0.0000 0.0017 0.0005 0.0047 0.0016 0.0231 0.0099 0.0540 0.0309 0.1005 0.0574 0.1816 0.1030 0.3028 0.2870 0.3314 0.5097 0.1740 0.3416 0.2290 0.2805 0.1980 0.1584 0.1530 0.1041 0.1140 0.0679 0.0770 0.0181 0.0260 0.0158 0.0230 0.0090 0.0060 0.0045 0.0029 0.0141 0.0417 0.0959 0.1617 0.2172 0.2159 0.1543 0.0962
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 270 229 image if available 650 7025 1251.1 283.87 11.58 3.56 859 957 1050 1150 1249 1356 1450 1553 1640 0.0757 532 1.003 35.47 12.37 1 0.1554 101 0.0018 76.01 6.355 0.1286 1650000.0
2260000000
3210000000000
4.71E+15
0.3546 0.2714 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0030 0.0000 0.0861 0.0357 0.1632 0.0683 0.0950 0.0233 0.1424 0.0714 0.5104 0.8012 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0020 0.0000 0.0405 0.0356 0.0729 0.0681 0.0304 0.0232 0.0547 0.0464 0.7996 0.8266 0.0000 1.0000 0.0000 0.0000 0.0000 0.0000 0.0127 0.0000 0.0828 0.0000 0.1083 0.0000 0.0573 0.0000 0.1083 0.0000 0.6306 0.0000 0.0000 0.0000 0.0000 0.0093 0.0556 0.0710 0.0525 0.0556 0.7562 7 9 10 11 11 12 13 14 16 0.0081 16.06 5.190 0.2777 146.9
2017.49
29808.4
471003
0.4942 0.1529 0.0108 0.0007 0.0396 0.0047 0.0930 0.0132 0.1508 0.0346 0.2124 0.0636 0.2362 0.1307 0.1635 0.2187 0.0792 0.3144 0.0144 0.2194 0.0046 0.0002 0.0197 0.0029 0.0427 0.0088 0.0534 0.0212 0.0813 0.0412 0.1242 0.0726 0.1697 0.1078 0.2247 0.2453 0.2797 0.5001 0.1226 0.2147 0.1534 0.1587 0.1534 0.1635 0.1480 0.1346 0.1180 0.1010 0.0987 0.0737 0.0887 0.0561 0.0717 0.0657 0.0455 0.0321 0.0277 0.0639 0.0858 0.1141 0.1354 0.1515 0.1521 0.1263 0.1433
BT-20 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 153 139 image if available 5758 11802 360.4 40.57 302.04 287.41 307 326 339 350 361 372 383 396 412 0.0835 986 0.859 110.32 27.29 1 0.0455 262 0.0019 22.05 6.508 0.2365 131562.0
48600000
18200000000
6860000000000
0.4593 0.1900 0.0002 0.0000 0.0006 0.0000 0.0011 0.0000 0.0030 0.0002 0.0199 0.0116 0.0345 0.0200 0.0450 0.0106 0.0849 0.0181 0.8109 0.9396 0.0000 0.0000 0.0000 0.0000 0.0005 0.0000 0.0025 0.0002 0.0165 0.0116 0.0244 0.0200 0.0244 0.0106 0.0400 0.0181 0.8916 0.9396 0.0419 0.0000 0.1204 0.0000 0.1414 0.0000 0.1204 0.0000 0.0942 0.0000 0.1204 0.0000 0.1099 0.0000 0.1099 0.0000 0.1414 0.0000 0.0027 0.0030 0.0172 0.0320 0.0573 0.1004 0.1018 0.1375 0.5480 23 35 59 111 207 327 442 575 737 0.0095 68.30 6.730 0.3226 173824.0
123000000
98700000000
86100000000000
0.4300 0.1996 0.0309 0.0016 0.1561 0.0094 0.2346 0.0661 0.1920 0.1351 0.1669 0.2033 0.1068 0.2090 0.0576 0.1286 0.0434 0.1167 0.0117 0.1302 0.0002 0.0000 0.0004 0.0002 0.0011 0.0013 0.0078 0.0063 0.0446 0.0401 0.0822 0.0683 0.0522 0.0435 0.0816 0.0691 0.7299 0.7711 0.0005 0.0003 0.0007 0.0019 0.0032 0.0051 0.0178 0.0177 0.0597 0.0756 0.1097 0.1293 0.0834 0.0942 0.1134 0.1322 0.6116 0.5437 0.0000 0.0002 0.0008 0.0107 0.0530 0.0945 0.0643 0.1014 0.6751
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 349 807 image if available 6538 12626 588.0 86.69 128.31 222.66 469 530 562 584 602 620 637 657 683 0.0673 850 0.775 146.56 30.15 1 0.0509 333 0.0010 44.42 7.238 0.1938 353259.0
216000000
134000000000
83900000000000
0.4229 0.2180 0.0000 0.0000 0.0002 0.0000 0.0007 0.0000 0.0030 0.0002 0.0197 0.0106 0.0355 0.0173 0.0365 0.0112 0.0673 0.0176 0.8370 0.9433 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0015 0.0002 0.0129 0.0106 0.0221 0.0173 0.0201 0.0112 0.0312 0.0176 0.9121 0.9433 0.0276 0.0000 0.0379 0.0000 0.0379 0.0000 0.1241 0.0000 0.1310 0.0000 0.1586 0.0000 0.1241 0.0000 0.0931 0.0000 0.2655 0.0000 0.0011 0.0034 0.0053 0.0169 0.0344 0.0573 0.0655 0.0922 0.7238 11 13 16 21 29 46 87 188 404 0.1397 11.93 3.675 0.6149 66036.9
54600000
58200000000
74400000000000
0.4876 0.1751 0.0820 0.0077 0.2182 0.0463 0.2753 0.1683 0.1406 0.1143 0.1083 0.1550 0.0849 0.1907 0.0395 0.1066 0.0249 0.0863 0.0264 0.1248 0.0000 0.0005 0.0009 0.0010 0.0026 0.0022 0.0131 0.0124 0.0707 0.0604 0.0993 0.0897 0.0678 0.0592 0.1013 0.0905 0.6443 0.6841 0.0000 0.0004 0.0004 0.0004 0.0039 0.0019 0.0218 0.0250 0.0761 0.0832 0.1208 0.1271 0.0778 0.0847 0.1127 0.1144 0.5866 0.5630 0.0003 0.0003 0.0029 0.0147 0.0809 0.1055 0.0723 0.1125 0.6106
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 125 813 image if available 4044 8852 602.6 91.52 41.19 63.75 467 546 581 603 621 637 653 670 697 0.0916 811 0.861 103.18 25.63 4 0.0601 243 0.0019 32.85 6.649 0.2422 371488.0
233000000
149000000000
95900000000000
0.4344 0.2018 0.0000 0.0000 0.0000 0.0000 0.0006 0.0000 0.0029 0.0008 0.0262 0.0168 0.0455 0.0300 0.0385 0.0173 0.0691 0.0297 0.8172 0.9055 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0011 0.0008 0.0201 0.0167 0.0321 0.0289 0.0201 0.0157 0.0338 0.0282 0.8928 0.9097 0.0279 0.0000 0.0391 0.0000 0.0615 0.1429 0.1006 0.2857 0.1006 0.2857 0.1564 0.2857 0.1229 0.0000 0.0950 0.0000 0.2961 0.0000 0.0008 0.0021 0.0062 0.0181 0.0402 0.0743 0.0812 0.0952 0.6820 9 11 14 16 19 24 32 45 88 0.0559 3.74 3.856 0.6364 5760.6
1520000
505000000
191000000000
0.4879 0.1680 0.0222 0.0179 0.0677 0.0335 0.0812 0.0288 0.1141 0.0594 0.1460 0.0957 0.1470 0.0868 0.1692 0.1094 0.1335 0.1627 0.1190 0.4059 0.0058 0.0099 0.0173 0.0192 0.0142 0.0128 0.0242 0.0271 0.0468 0.0434 0.0560 0.0449 0.0629 0.0545 0.0844 0.0813 0.6884 0.7067 0.0032 0.0069 0.0153 0.0122 0.0159 0.0130 0.0312 0.0298 0.0503 0.0519 0.0751 0.0833 0.0649 0.0596 0.0808 0.0795 0.6635 0.6639 0.0049 0.0113 0.0157 0.0300 0.0458 0.0679 0.0684 0.0915 0.6644
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 699 471 image if available 4304 9250 675.2 100.28 112.63 227.13 526 609 656 678 694 707 722 740 781 0.0782 723 1.058 105.04 31.11 1 0.0602 259 0.0017 29.52 6.816 0.2429 465980.0
327000000
234000000000
169000000000000
0.4313 0.2103 0.0000 0.0000 0.0000 0.0000 0.0008 0.0000 0.0028 0.0000 0.0204 0.0139 0.0353 0.0238 0.0311 0.0120 0.0487 0.0205 0.8609 0.9297 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0016 0.0000 0.0149 0.0139 0.0259 0.0238 0.0191 0.0120 0.0254 0.0205 0.9130 0.9297 0.0082 0.0000 0.0163 0.0000 0.0245 0.0000 0.0367 0.0000 0.0816 0.0000 0.0857 0.0000 0.0816 0.0000 0.1143 0.0000 0.5510 0.0000 0.0004 0.0015 0.0038 0.0128 0.0342 0.0556 0.0680 0.0992 0.7244 8 10 12 14 17 26 59 148 341 0.1976 21.25 3.579 0.6813 64269.9
61100000
74500000000
106000000000000
0.4869 0.1485 0.0430 0.0000 0.1471 0.0171 0.1991 0.0910 0.1222 0.1229 0.1357 0.1456 0.1154 0.1581 0.1086 0.1229 0.0633 0.1024 0.0656 0.2400 0.0000 0.0000 0.0008 0.0004 0.0013 0.0011 0.0109 0.0094 0.0419 0.0410 0.0747 0.0556 0.0516 0.0402 0.0763 0.0676 0.7425 0.7847 0.0000 0.0006 0.0010 0.0022 0.0031 0.0028 0.0175 0.0185 0.0577 0.0612 0.0911 0.1021 0.0695 0.0606 0.0901 0.0948 0.6699 0.6571 0.0000 0.0009 0.0032 0.0125 0.0529 0.0779 0.0682 0.0904 0.6939
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 284 471 image if available 1555 4253 401.1 47.90 19.31 18.63 332 364 381 394 406 416 429 441 459 0.0997 424 1.147 61.20 22.02 1 0.1016 158 0.0027 20.18 6.139 0.2451 163138.0
67200000
28000000000
11800000000000
0.4443 0.1979 0.0000 0.0000 0.0000 0.0000 0.0007 0.0000 0.0028 0.0006 0.0285 0.0239 0.0463 0.0303 0.0484 0.0232 0.0855 0.0342 0.7877 0.8877 0.0000 0.0000 0.0000 0.0000 0.0007 0.0000 0.0028 0.0006 0.0241 0.0239 0.0345 0.0303 0.0241 0.0232 0.0427 0.0342 0.8711 0.8877 0.0426 0.0000 0.1064 0.0000 0.1064 0.0000 0.1277 0.0000 0.2340 0.0000 0.1702 0.0000 0.0638 0.0000 0.1064 0.0000 0.0426 0.0000 0.0000 0.0060 0.0072 0.0358 0.0656 0.1144 0.1085 0.1323 0.5304 8 10 11 13 14 16 18 23 33 0.2369 0.56 2.092 0.8275 719.8
57928.3
7540000
1230000000
0.5877 0.1129 0.1023 0.0171 0.1338 0.0274 0.1250 0.0499 0.1439 0.0846 0.1452 0.1170 0.1351 0.1471 0.1225 0.1498 0.0682 0.1619 0.0240 0.2452 0.0447 0.0107 0.0494 0.0169 0.0353 0.0331 0.0358 0.0562 0.0529 0.0841 0.0764 0.1041 0.0781 0.1013 0.1193 0.1162 0.5082 0.4774 0.0132 0.0162 0.0154 0.0310 0.0209 0.0398 0.0473 0.0516 0.0780 0.0634 0.0978 0.1165 0.1022 0.0870 0.1516 0.1608 0.4736 0.4336 0.0277 0.0317 0.0222 0.0301 0.0586 0.0705 0.0777 0.1474 0.5341
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 646 621 image if available 554 3317 275.3 19.34 19.44 28.31 251 261 267 272 276 281 286 292 299 0.1007 334 0.832 128.55 29.97 1 0.5108 283 0.0078 11.20 5.111 0.3312 76161.1
21200000
5910000000
1660000000000
0.3922 0.2458 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0453 0.0451 0.0652 0.0650 0.0380 0.0307 0.0580 0.0469 0.7935 0.8123 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0453 0.0451 0.0652 0.0650 0.0380 0.0307 0.0580 0.0469 0.7935 0.8123 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0067 0.0100 0.0300 0.0533 0.0900 0.1667 0.1333 0.1567 0.3533 7 8 9 9 11 12 15 22 33 0.0979 0.55 1.508 0.4506 1178.9
161332
29100000
5860000000
0.5686 0.1153 0.0480 0.0687 0.1051 0.0634 0.1471 0.0569 0.1952 0.0838 0.2462 0.0967 0.1532 0.1267 0.0811 0.1590 0.0210 0.2105 0.0030 0.1343 0.0121 0.0433 0.0141 0.0377 0.0121 0.0314 0.0313 0.0328 0.0555 0.0370 0.0757 0.0656 0.0858 0.0628 0.1171 0.1172 0.5964 0.5722 0.0091 0.0139 0.0106 0.0239 0.0152 0.0359 0.0410 0.0478 0.0699 0.0896 0.1307 0.1116 0.1185 0.1116 0.1413 0.1434 0.4635 0.4223 0.0059 0.0059 0.0118 0.0403 0.0557 0.0853 0.0936 0.1256 0.5758