High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 798 | 428 | | 27432 | 45118 | 211.1 | 59.97 | 98.82 | 173.21 | 140 | 162 | 179 | 194 | 208 | 223 | 239 | 258 | 287 | 0.0427 | 1927 | 0.804 | 104.04 | 21.19 | 1 | 0.0082 | 226 | 0.0007 | 43.54 | 7.545 | 0.1862 | 48158.5 | 11800000 | 3050000000 | 838000000000 | 0.4170 | 0.2298 | 0.0009 | 0.0000 | 0.0014 | 0.0001 | 0.0072 | 0.0005 | 0.0254 | 0.0026 | 0.0661 | 0.0188 | 0.1224 | 0.0410 | 0.1361 | 0.0439 | 0.1737 | 0.0674 | 0.4667 | 0.8259 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0001 | 0.0072 | 0.0009 | 0.0239 | 0.0093 | 0.0448 | 0.0189 | 0.0494 | 0.0177 | 0.0650 | 0.0292 | 0.8061 | 0.9239 | 0.0049 | 0.0049 | 0.0082 | 0.0175 | 0.0196 | 0.0265 | 0.0469 | 0.0746 | 0.0894 | 0.1169 | 0.1266 | 0.1677 | 0.1090 | 0.1102 | 0.1271 | 0.1250 | 0.4683 | 0.3566 | 0.0014 | 0.0023 | 0.0066 | 0.0227 | 0.0535 | 0.0917 | 0.0877 | 0.1135 | 0.6206 | 10 | 12 | 14 | 16 | 20 | 29 | 54 | 137 | 332 | 0.1819 | 23.17 | 3.891 | 0.6587 | 39767.1 | 24100000 | 17400000000 | 14100000000000 | 0.4082 | 0.2647 | 0.1462 | 0.0039 | 0.3078 | 0.0465 | 0.2795 | 0.2378 | 0.1040 | 0.2151 | 0.0818 | 0.2042 | 0.0463 | 0.1441 | 0.0206 | 0.0647 | 0.0093 | 0.0494 | 0.0046 | 0.0343 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0015 | 0.0011 | 0.0142 | 0.0095 | 0.0704 | 0.0604 | 0.0987 | 0.0930 | 0.0678 | 0.0551 | 0.1104 | 0.0943 | 0.6360 | 0.6860 | 0.0003 | 0.0000 | 0.0017 | 0.0017 | 0.0033 | 0.0043 | 0.0185 | 0.0216 | 0.0848 | 0.0897 | 0.1211 | 0.1251 | 0.0804 | 0.0863 | 0.1188 | 0.1212 | 0.5710 | 0.5502 | 0.0001 | 0.0006 | 0.0030 | 0.0167 | 0.0751 | 0.1185 | 0.0740 | 0.1117 | 0.6002 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 171 | 227 | | 13156 | 26560 | 216.3 | 55.08 | 143.33 | 196.83 | 147 | 172 | 189 | 203 | 217 | 231 | 246 | 263 | 286 | 0.0570 | 1514 | 0.695 | 170.21 | 47.54 | 3 | 0.0364 | 479 | 0.0008 | 42.66 | 7.414 | 0.1765 | 49810.3 | 12100000 | 3040000000 | 797000000000 | 0.4175 | 0.2260 | 0.0007 | 0.0001 | 0.0014 | 0.0001 | 0.0076 | 0.0009 | 0.0228 | 0.0052 | 0.0655 | 0.0153 | 0.1188 | 0.0349 | 0.1344 | 0.0418 | 0.1753 | 0.0659 | 0.4735 | 0.8359 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0004 | 0.0075 | 0.0020 | 0.0220 | 0.0098 | 0.0398 | 0.0182 | 0.0480 | 0.0148 | 0.0644 | 0.0241 | 0.8168 | 0.9308 | 0.0028 | 0.0282 | 0.0118 | 0.0267 | 0.0277 | 0.0847 | 0.0602 | 0.1278 | 0.0906 | 0.1798 | 0.1387 | 0.1575 | 0.1280 | 0.1189 | 0.1505 | 0.1218 | 0.3898 | 0.1545 | 0.0012 | 0.0034 | 0.0079 | 0.0230 | 0.0477 | 0.0880 | 0.0938 | 0.1052 | 0.6296 | 16 | 19 | 22 | 26 | 40 | 80 | 154 | 256 | 424 | 0.0499 | 24.57 | 5.020 | 0.5076 | 59283.3 | 35800000 | 26400000000 | 22500000000000 | 0.6077 | 0.0916 | 0.0465 | 0.0024 | 0.1573 | 0.0221 | 0.2370 | 0.0945 | 0.1899 | 0.1299 | 0.1567 | 0.1853 | 0.1107 | 0.1877 | 0.0559 | 0.1296 | 0.0288 | 0.1216 | 0.0172 | 0.1270 | 0.0004 | 0.0003 | 0.0007 | 0.0014 | 0.0025 | 0.0019 | 0.0149 | 0.0139 | 0.0556 | 0.0499 | 0.0753 | 0.0693 | 0.0592 | 0.0511 | 0.0899 | 0.0801 | 0.7015 | 0.7321 | 0.0005 | 0.0015 | 0.0016 | 0.0014 | 0.0046 | 0.0059 | 0.0219 | 0.0234 | 0.0658 | 0.0751 | 0.1028 | 0.1190 | 0.0811 | 0.0870 | 0.1118 | 0.1202 | 0.6099 | 0.5665 | 0.0007 | 0.0013 | 0.0027 | 0.0190 | 0.0556 | 0.0905 | 0.0669 | 0.0992 | 0.6642 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 501 | 504 | | 10483 | 29050 | 333.7 | 87.79 | 177.85 | 262.57 | 236 | 272 | 293 | 313 | 331 | 350 | 372 | 400 | 442 | 0.0518 | 1504 | 0.386 | 149.64 | 20.59 | 5 | 0.0405 | 425 | 0.0005 | 88.21 | 7.897 | 0.1404 | 119081.0 | 44900000 | 17800000000 | 7380000000000 | 0.4581 | 0.1796 | 0.0000 | 0.0000 | 0.0012 | 0.0001 | 0.0040 | 0.0003 | 0.0124 | 0.0024 | 0.0524 | 0.0199 | 0.0976 | 0.0409 | 0.1048 | 0.0282 | 0.1371 | 0.0397 | 0.5905 | 0.8683 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0043 | 0.0009 | 0.0218 | 0.0129 | 0.0408 | 0.0249 | 0.0434 | 0.0140 | 0.0546 | 0.0203 | 0.8331 | 0.9269 | 0.0063 | 0.0043 | 0.0058 | 0.0029 | 0.0184 | 0.0200 | 0.0442 | 0.0428 | 0.0738 | 0.1056 | 0.1169 | 0.1469 | 0.1004 | 0.0984 | 0.1145 | 0.1213 | 0.5197 | 0.4579 | 0.0012 | 0.0029 | 0.0078 | 0.0171 | 0.0536 | 0.0699 | 0.0740 | 0.0962 | 0.6774 | 11 | 14 | 18 | 25 | 50 | 97 | 178 | 304 | 548 | 0.0648 | 33.20 | 5.292 | 0.5122 | 100572.0 | 82800000 | 82800000000 | 94100000000000 | 0.3716 | 0.2666 | 0.0296 | 0.0017 | 0.1361 | 0.0083 | 0.2160 | 0.0670 | 0.1652 | 0.1170 | 0.1568 | 0.1755 | 0.1326 | 0.1840 | 0.0774 | 0.1333 | 0.0483 | 0.1272 | 0.0380 | 0.1861 | 0.0001 | 0.0003 | 0.0009 | 0.0003 | 0.0034 | 0.0025 | 0.0112 | 0.0111 | 0.0428 | 0.0397 | 0.0676 | 0.0625 | 0.0535 | 0.0451 | 0.0718 | 0.0631 | 0.7487 | 0.7755 | 0.0005 | 0.0007 | 0.0015 | 0.0023 | 0.0044 | 0.0056 | 0.0156 | 0.0203 | 0.0529 | 0.0545 | 0.0833 | 0.0881 | 0.0667 | 0.0649 | 0.0827 | 0.0819 | 0.6924 | 0.6817 | 0.0002 | 0.0008 | 0.0029 | 0.0164 | 0.0438 | 0.0782 | 0.0630 | 0.0794 | 0.7154 | ||
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 334 | 363 | | 15302 | 41714 | 244.9 | 60.87 | 131.95 | 179.42 | 171 | 196 | 213 | 227 | 242 | 257 | 273 | 292 | 320 | 0.0338 | 1411 | 0.710 | 67.01 | 10.63 | 1 | 0.0092 | 141 | 0.0009 | 32.33 | 7.369 | 0.2155 | 63663.8 | 17500000 | 5040000000 | 1520000000000 | 0.3811 | 0.2520 | 0.0003 | 0.0001 | 0.0018 | 0.0001 | 0.0054 | 0.0012 | 0.0129 | 0.0025 | 0.0443 | 0.0131 | 0.0775 | 0.0277 | 0.0883 | 0.0259 | 0.1303 | 0.0318 | 0.6391 | 0.8975 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0005 | 0.0043 | 0.0006 | 0.0157 | 0.0082 | 0.0271 | 0.0149 | 0.0311 | 0.0107 | 0.0502 | 0.0147 | 0.8688 | 0.9504 | 0.0040 | 0.0021 | 0.0074 | 0.0094 | 0.0148 | 0.0178 | 0.0415 | 0.0545 | 0.0820 | 0.1027 | 0.1180 | 0.1394 | 0.0981 | 0.1038 | 0.1164 | 0.1153 | 0.5177 | 0.4549 | 0.0010 | 0.0043 | 0.0084 | 0.0193 | 0.0357 | 0.0673 | 0.0704 | 0.0887 | 0.7048 | 13 | 17 | 21 | 29 | 47 | 80 | 136 | 229 | 381 | 0.0427 | 30.07 | 5.192 | 0.5095 | 49598.6 | 28100000 | 20000000000 | 16800000000000 | 0.3211 | 0.3337 | 0.0612 | 0.0021 | 0.1948 | 0.0183 | 0.2759 | 0.1123 | 0.1692 | 0.1501 | 0.1266 | 0.2025 | 0.0897 | 0.1912 | 0.0381 | 0.1170 | 0.0295 | 0.0975 | 0.0151 | 0.1089 | 0.0001 | 0.0001 | 0.0003 | 0.0005 | 0.0017 | 0.0013 | 0.0140 | 0.0104 | 0.0568 | 0.0497 | 0.0959 | 0.0827 | 0.0647 | 0.0548 | 0.0965 | 0.0855 | 0.6699 | 0.7149 | 0.0002 | 0.0004 | 0.0005 | 0.0012 | 0.0029 | 0.0045 | 0.0170 | 0.0211 | 0.0778 | 0.0843 | 0.1185 | 0.1332 | 0.0800 | 0.0874 | 0.1208 | 0.1226 | 0.5822 | 0.5453 | 0.0002 | 0.0013 | 0.0024 | 0.0139 | 0.0650 | 0.1091 | 0.0726 | 0.1074 | 0.6281 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 207 | 478 | | 13048 | 26519 | 97.0 | 27.99 | 161.98 | 234.77 | 64 | 74 | 81 | 88 | 95 | 102 | 109 | 119 | 134 | 0.0514 | 1363 | 0.414 | 318.40 | 44.82 | 2 | 0.0676 | 882 | 0.0022 | 19.38 | 6.429 | 0.2488 | 10191.1 | 1150000 | 139000000 | 17800000000 | 0.4486 | 0.1898 | 0.0006 | 0.0001 | 0.0026 | 0.0001 | 0.0142 | 0.0005 | 0.0573 | 0.0057 | 0.1294 | 0.0245 | 0.1873 | 0.0596 | 0.1931 | 0.0819 | 0.1988 | 0.1265 | 0.2168 | 0.7010 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0002 | 0.0123 | 0.0021 | 0.0425 | 0.0125 | 0.0796 | 0.0275 | 0.0907 | 0.0335 | 0.1311 | 0.0529 | 0.6415 | 0.8713 | 0.0086 | 0.0180 | 0.0124 | 0.0237 | 0.0341 | 0.0606 | 0.0834 | 0.1219 | 0.1405 | 0.1457 | 0.1777 | 0.1833 | 0.1230 | 0.1129 | 0.1467 | 0.1211 | 0.2735 | 0.2128 | 0.0013 | 0.0034 | 0.0092 | 0.0433 | 0.0938 | 0.1445 | 0.1259 | 0.1491 | 0.4295 | 12 | 14 | 16 | 18 | 33 | 81 | 172 | 311 | 501 | 0.1539 | 30.24 | 4.603 | 0.5818 | 81353.0 | 57600000 | 49500000000 | 48800000000000 | 0.6313 | 0.0832 | 0.0968 | 0.0061 | 0.2891 | 0.0382 | 0.3119 | 0.2073 | 0.1514 | 0.1858 | 0.0786 | 0.1931 | 0.0396 | 0.1633 | 0.0221 | 0.0966 | 0.0084 | 0.0664 | 0.0019 | 0.0433 | 0.0002 | 0.0001 | 0.0014 | 0.0006 | 0.0029 | 0.0019 | 0.0159 | 0.0126 | 0.0664 | 0.0555 | 0.1013 | 0.0925 | 0.0752 | 0.0680 | 0.1062 | 0.0957 | 0.6305 | 0.6731 | 0.0001 | 0.0004 | 0.0027 | 0.0026 | 0.0041 | 0.0069 | 0.0213 | 0.0238 | 0.0829 | 0.0859 | 0.1261 | 0.1347 | 0.0905 | 0.1014 | 0.1246 | 0.1340 | 0.5478 | 0.5103 | 0.0002 | 0.0021 | 0.0035 | 0.0166 | 0.0752 | 0.1103 | 0.0892 | 0.1185 | 0.5844 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 156 | 594 | | 9080 | 15618 | 311.0 | 68.29 | 98.46 | 121.64 | 229 | 251 | 270 | 288 | 305 | 324 | 344 | 367 | 401 | 0.0788 | 1231 | 0.960 | 135.72 | 35.01 | 1 | 0.0352 | 320 | 0.0013 | 28.86 | 6.929 | 0.2122 | 101409.0 | 34600000 | 12300000000 | 4590000000000 | 0.4537 | 0.2035 | 0.0010 | 0.0000 | 0.0019 | 0.0001 | 0.0068 | 0.0009 | 0.0222 | 0.0025 | 0.0705 | 0.0167 | 0.1362 | 0.0410 | 0.1452 | 0.0416 | 0.1613 | 0.0640 | 0.4548 | 0.8331 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0006 | 0.0099 | 0.0020 | 0.0293 | 0.0115 | 0.0662 | 0.0283 | 0.0633 | 0.0223 | 0.0823 | 0.0364 | 0.7452 | 0.8989 | 0.0056 | 0.0027 | 0.0124 | 0.0318 | 0.0204 | 0.0637 | 0.0667 | 0.1141 | 0.1248 | 0.2042 | 0.1513 | 0.1485 | 0.1328 | 0.0716 | 0.1575 | 0.1300 | 0.3286 | 0.2334 | 0.0007 | 0.0030 | 0.0096 | 0.0287 | 0.0674 | 0.1168 | 0.1070 | 0.1261 | 0.5408 | 12 | 14 | 17 | 23 | 41 | 74 | 118 | 173 | 260 | 0.0390 | 25.52 | 5.297 | 0.4490 | 24490.2 | 9030000 | 4150000000 | 2200000000000 | 0.5460 | 0.1292 | 0.0690 | 0.0018 | 0.1999 | 0.0187 | 0.2994 | 0.1257 | 0.1613 | 0.1617 | 0.1323 | 0.2185 | 0.0814 | 0.1892 | 0.0378 | 0.1186 | 0.0145 | 0.0981 | 0.0044 | 0.0678 | 0.0002 | 0.0003 | 0.0012 | 0.0006 | 0.0031 | 0.0027 | 0.0151 | 0.0124 | 0.0691 | 0.0593 | 0.1090 | 0.0934 | 0.0785 | 0.0690 | 0.1141 | 0.1000 | 0.6096 | 0.6622 | 0.0011 | 0.0015 | 0.0023 | 0.0025 | 0.0079 | 0.0093 | 0.0234 | 0.0284 | 0.0888 | 0.0944 | 0.1239 | 0.1444 | 0.0960 | 0.0946 | 0.1298 | 0.1284 | 0.5268 | 0.4966 | 0.0002 | 0.0022 | 0.0039 | 0.0202 | 0.0788 | 0.1208 | 0.0884 | 0.1238 | 0.5618 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 826 | 707 | | 7372 | 21148 | 252.5 | 53.79 | 169.89 | 208.84 | 187 | 203 | 217 | 232 | 247 | 263 | 279 | 299 | 324 | 0.0440 | 931 | 0.980 | 86.83 | 30.02 | 1 | 0.0311 | 229 | 0.0008 | 53.24 | 7.330 | 0.1651 | 66652.7 | 18400000 | 5290000000 | 1590000000000 | 0.4618 | 0.1983 | 0.0000 | 0.0000 | 0.0015 | 0.0001 | 0.0048 | 0.0000 | 0.0231 | 0.0016 | 0.0808 | 0.0131 | 0.1549 | 0.0265 | 0.1579 | 0.0260 | 0.1862 | 0.0450 | 0.3908 | 0.8876 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0101 | 0.0005 | 0.0353 | 0.0083 | 0.0679 | 0.0166 | 0.0713 | 0.0101 | 0.0901 | 0.0194 | 0.7234 | 0.9451 | 0.0023 | 0.0073 | 0.0083 | 0.0366 | 0.0264 | 0.0623 | 0.0746 | 0.1282 | 0.1432 | 0.1758 | 0.1907 | 0.1319 | 0.1311 | 0.1575 | 0.1409 | 0.0989 | 0.2826 | 0.2015 | 0.0003 | 0.0044 | 0.0075 | 0.0232 | 0.0786 | 0.1193 | 0.0987 | 0.1425 | 0.5255 | 10 | 12 | 15 | 27 | 67 | 141 | 237 | 331 | 459 | 0.0738 | 28.37 | 5.373 | 0.4963 | 72475.9 | 42400000 | 31000000000 | 26900000000000 | 0.4734 | 0.1923 | 0.0494 | 0.0029 | 0.2224 | 0.0070 | 0.3468 | 0.1140 | 0.1622 | 0.2051 | 0.0962 | 0.2533 | 0.0622 | 0.2019 | 0.0327 | 0.0889 | 0.0186 | 0.0625 | 0.0096 | 0.0644 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0070 | 0.0057 | 0.0424 | 0.0396 | 0.0866 | 0.0755 | 0.0557 | 0.0466 | 0.0794 | 0.0711 | 0.7274 | 0.7607 | 0.0001 | 0.0000 | 0.0007 | 0.0005 | 0.0014 | 0.0028 | 0.0130 | 0.0161 | 0.0580 | 0.0627 | 0.1058 | 0.1260 | 0.0772 | 0.0841 | 0.1033 | 0.1156 | 0.6404 | 0.5922 | 0.0000 | 0.0009 | 0.0017 | 0.0096 | 0.0496 | 0.0965 | 0.0657 | 0.0897 | 0.6863 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 854 | 416 | | 11131 | 15417 | 454.3 | 71.88 | 90.38 | 157.98 | 358 | 393 | 418 | 438 | 454 | 468 | 484 | 508 | 549 | 0.0688 | 1061 | 1.159 | 147.22 | 49.48 | 2 | 0.0314 | 350 | 0.0013 | 17.13 | 6.964 | 0.2615 | 211570.0 | 101000000 | 49300000000 | 24600000000000 | 0.4019 | 0.2435 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0025 | 0.0005 | 0.0056 | 0.0007 | 0.0198 | 0.0107 | 0.0364 | 0.0188 | 0.0370 | 0.0124 | 0.0542 | 0.0178 | 0.8429 | 0.9388 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0023 | 0.0002 | 0.0110 | 0.0093 | 0.0213 | 0.0169 | 0.0198 | 0.0089 | 0.0278 | 0.0138 | 0.9153 | 0.9509 | 0.0058 | 0.0159 | 0.0075 | 0.0397 | 0.0100 | 0.0556 | 0.0325 | 0.1270 | 0.0600 | 0.0873 | 0.0783 | 0.1349 | 0.0666 | 0.1111 | 0.0966 | 0.0952 | 0.6428 | 0.3333 | 0.0012 | 0.0023 | 0.0068 | 0.0178 | 0.0371 | 0.0570 | 0.0697 | 0.0892 | 0.7189 | 7 | 9 | 10 | 11 | 14 | 23 | 53 | 139 | 311 | 0.2296 | 12.11 | 3.590 | 0.7091 | 33126.6 | 17600000 | 11100000000 | 7920000000000 | 0.5835 | 0.1060 | 0.0228 | 0.0066 | 0.0791 | 0.0185 | 0.1263 | 0.0524 | 0.1948 | 0.0739 | 0.1933 | 0.1344 | 0.1522 | 0.1839 | 0.0898 | 0.1440 | 0.0883 | 0.1322 | 0.0533 | 0.2541 | 0.0000 | 0.0006 | 0.0012 | 0.0017 | 0.0021 | 0.0039 | 0.0062 | 0.0067 | 0.0321 | 0.0323 | 0.0482 | 0.0424 | 0.0349 | 0.0336 | 0.0634 | 0.0528 | 0.8120 | 0.8259 | 0.0011 | 0.0003 | 0.0031 | 0.0018 | 0.0025 | 0.0028 | 0.0098 | 0.0104 | 0.0419 | 0.0429 | 0.0613 | 0.0726 | 0.0526 | 0.0643 | 0.0793 | 0.0867 | 0.7482 | 0.7182 | 0.0003 | 0.0013 | 0.0028 | 0.0103 | 0.0339 | 0.0573 | 0.0419 | 0.0637 | 0.7885 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 245 | | 7441 | 18098 | 595.1 | 99.87 | 158.05 | 276.24 | 459 | 515 | 549 | 576 | 598 | 618 | 640 | 669 | 725 | 0.0530 | 960 | 0.791 | 112.90 | 27.89 | 2 | 0.0372 | 277 | 0.0011 | 26.39 | 7.165 | 0.2288 | 364116.0 | 229000000 | 147000000000 | 96900000000000 | 0.4475 | 0.1984 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0016 | 0.0000 | 0.0053 | 0.0005 | 0.0258 | 0.0124 | 0.0455 | 0.0206 | 0.0458 | 0.0151 | 0.0692 | 0.0230 | 0.8059 | 0.9282 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0003 | 0.0163 | 0.0116 | 0.0267 | 0.0174 | 0.0252 | 0.0115 | 0.0358 | 0.0181 | 0.8938 | 0.9412 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0292 | 0.0000 | 0.0560 | 0.0000 | 0.0840 | 0.0000 | 0.0793 | 0.0000 | 0.1039 | 0.0000 | 0.6196 | 0.0000 | 0.0018 | 0.0036 | 0.0094 | 0.0214 | 0.0420 | 0.0641 | 0.0646 | 0.0876 | 0.7055 | 11 | 14 | 17 | 20 | 25 | 35 | 85 | 239 | 575 | 0.1535 | 16.74 | 4.037 | 0.6476 | 101285.0 | 90600000 | 95000000000 | 112000000000000 | 0.3437 | 0.2785 | 0.0470 | 0.0020 | 0.1678 | 0.0214 | 0.1893 | 0.0935 | 0.1530 | 0.1136 | 0.1732 | 0.1877 | 0.0980 | 0.1717 | 0.0779 | 0.1236 | 0.0671 | 0.1142 | 0.0268 | 0.1723 | 0.0002 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0013 | 0.0102 | 0.0086 | 0.0376 | 0.0335 | 0.0599 | 0.0539 | 0.0436 | 0.0392 | 0.0626 | 0.0588 | 0.7843 | 0.8046 | 0.0000 | 0.0003 | 0.0012 | 0.0000 | 0.0042 | 0.0040 | 0.0138 | 0.0138 | 0.0413 | 0.0458 | 0.0655 | 0.0684 | 0.0487 | 0.0468 | 0.0667 | 0.0620 | 0.7586 | 0.7589 | 0.0002 | 0.0007 | 0.0023 | 0.0114 | 0.0416 | 0.0654 | 0.0444 | 0.0633 | 0.7707 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 512 | 618 | | 11255 | 20255 | 428.2 | 87.05 | 105.63 | 203.30 | 309 | 354 | 384 | 408 | 429 | 449 | 474 | 501 | 549 | 0.0544 | 1102 | 0.683 | 111.73 | 25.46 | 6 | 0.0275 | 310 | 0.0009 | 22.99 | 7.263 | 0.2438 | 190902.0 | 88200000 | 42000000000 | 20600000000000 | 0.4424 | 0.2031 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0026 | 0.0004 | 0.0084 | 0.0012 | 0.0280 | 0.0134 | 0.0584 | 0.0238 | 0.0474 | 0.0178 | 0.0713 | 0.0278 | 0.7829 | 0.9155 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0008 | 0.0135 | 0.0104 | 0.0281 | 0.0209 | 0.0204 | 0.0124 | 0.0313 | 0.0184 | 0.9022 | 0.9370 | 0.0011 | 0.0000 | 0.0063 | 0.0000 | 0.0110 | 0.0000 | 0.0226 | 0.0000 | 0.0479 | 0.0000 | 0.0805 | 0.0000 | 0.0642 | 0.0000 | 0.0789 | 0.0000 | 0.6875 | 0.0000 | 0.0009 | 0.0019 | 0.0058 | 0.0140 | 0.0333 | 0.0539 | 0.0552 | 0.0744 | 0.7606 | 8 | 9 | 10 | 11 | 13 | 16 | 42 | 145 | 378 | 0.0720 | 5.26 | 3.153 | 0.4465 | 52486.1 | 36900000 | 30400000000 | 27900000000000 | 0.5667 | 0.1091 | 0.0648 | 0.0042 | 0.2221 | 0.0305 | 0.2455 | 0.1491 | 0.1821 | 0.1574 | 0.1255 | 0.1533 | 0.0690 | 0.1678 | 0.0331 | 0.1262 | 0.0317 | 0.0846 | 0.0262 | 0.1269 | 0.0004 | 0.0000 | 0.0006 | 0.0006 | 0.0010 | 0.0017 | 0.0112 | 0.0092 | 0.0467 | 0.0430 | 0.0696 | 0.0628 | 0.0485 | 0.0415 | 0.0752 | 0.0685 | 0.7467 | 0.7729 | 0.0005 | 0.0005 | 0.0007 | 0.0007 | 0.0016 | 0.0025 | 0.0113 | 0.0152 | 0.0565 | 0.0539 | 0.0774 | 0.0786 | 0.0493 | 0.0607 | 0.0870 | 0.0851 | 0.7156 | 0.7027 | 0.0007 | 0.0000 | 0.0020 | 0.0119 | 0.0543 | 0.0701 | 0.0508 | 0.0795 | 0.7308 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 835 | 668 | | 9436 | 26949 | 509.0 | 119.52 | 167.87 | 203.60 | 373 | 412 | 441 | 467 | 495 | 522 | 555 | 598 | 668 | 0.0413 | 1112 | 0.662 | 166.43 | 45.61 | 1 | 0.0520 | 491 | 0.0006 | 62.28 | 7.676 | 0.1552 | 273329.0 | 155000000 | 92900000000 | 58900000000000 | 0.4414 | 0.2158 | 0.0005 | 0.0000 | 0.0010 | 0.0001 | 0.0045 | 0.0001 | 0.0160 | 0.0016 | 0.0599 | 0.0173 | 0.1253 | 0.0382 | 0.1333 | 0.0410 | 0.1696 | 0.0533 | 0.4898 | 0.8484 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0056 | 0.0004 | 0.0284 | 0.0114 | 0.0665 | 0.0214 | 0.0584 | 0.0205 | 0.0867 | 0.0273 | 0.7535 | 0.9190 | 0.0030 | 0.0000 | 0.0095 | 0.0141 | 0.0233 | 0.0194 | 0.0531 | 0.0952 | 0.1103 | 0.1411 | 0.1455 | 0.1711 | 0.0960 | 0.0935 | 0.1306 | 0.1323 | 0.4287 | 0.3333 | 0.0002 | 0.0045 | 0.0079 | 0.0271 | 0.0857 | 0.1202 | 0.0911 | 0.1114 | 0.5519 | 8 | 11 | 17 | 36 | 77 | 141 | 218 | 316 | 466 | 0.0551 | 40.07 | 5.701 | 0.4557 | 69631.7 | 39300000 | 26800000000 | 21000000000000 | 0.4485 | 0.1832 | 0.0434 | 0.0008 | 0.1902 | 0.0126 | 0.2802 | 0.1166 | 0.1517 | 0.1613 | 0.1292 | 0.2019 | 0.0888 | 0.1955 | 0.0589 | 0.1175 | 0.0323 | 0.0958 | 0.0254 | 0.0979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0093 | 0.0067 | 0.0549 | 0.0483 | 0.1006 | 0.0833 | 0.0610 | 0.0527 | 0.0967 | 0.0874 | 0.6773 | 0.7214 | 0.0002 | 0.0004 | 0.0009 | 0.0003 | 0.0012 | 0.0017 | 0.0175 | 0.0227 | 0.0800 | 0.0909 | 0.1203 | 0.1382 | 0.0793 | 0.0819 | 0.1150 | 0.1299 | 0.5857 | 0.5341 | 0.0000 | 0.0002 | 0.0021 | 0.0123 | 0.0723 | 0.1039 | 0.0750 | 0.1098 | 0.6245 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1187 | 150 | | 10144 | 18089 | 422.6 | 104.34 | 134.81 | 165.74 | 292 | 329 | 360 | 387 | 413 | 441 | 470 | 509 | 564 | 0.0612 | 1107 | 0.929 | 101.98 | 22.83 | 1 | 0.0219 | 222 | 0.0007 | 49.57 | 7.512 | 0.1760 | 189470.0 | 89800000 | 44900000000 | 23500000000000 | 0.4318 | 0.2153 | 0.0002 | 0.0000 | 0.0024 | 0.0001 | 0.0055 | 0.0009 | 0.0213 | 0.0034 | 0.0707 | 0.0216 | 0.1408 | 0.0424 | 0.1325 | 0.0444 | 0.1711 | 0.0653 | 0.4554 | 0.8220 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0019 | 0.0004 | 0.0069 | 0.0013 | 0.0283 | 0.0125 | 0.0547 | 0.0201 | 0.0594 | 0.0179 | 0.0803 | 0.0312 | 0.7681 | 0.9165 | 0.0039 | 0.0043 | 0.0072 | 0.0130 | 0.0101 | 0.0391 | 0.0568 | 0.1014 | 0.0901 | 0.1681 | 0.1710 | 0.2087 | 0.1098 | 0.1087 | 0.1349 | 0.1406 | 0.4162 | 0.2159 | 0.0006 | 0.0029 | 0.0063 | 0.0240 | 0.0632 | 0.1112 | 0.1004 | 0.1280 | 0.5634 | 7 | 10 | 15 | 31 | 61 | 108 | 168 | 251 | 373 | 0.0482 | 25.89 | 5.272 | 0.4507 | 45643.3 | 21300000 | 12000000000 | 7760000000000 | 0.5745 | 0.1113 | 0.0713 | 0.0037 | 0.2521 | 0.0324 | 0.2954 | 0.1786 | 0.1297 | 0.1970 | 0.0926 | 0.1848 | 0.0798 | 0.1557 | 0.0420 | 0.0909 | 0.0207 | 0.0701 | 0.0164 | 0.0869 | 0.0003 | 0.0000 | 0.0006 | 0.0001 | 0.0007 | 0.0005 | 0.0145 | 0.0119 | 0.0699 | 0.0593 | 0.1238 | 0.1008 | 0.0735 | 0.0705 | 0.1173 | 0.1039 | 0.5995 | 0.6530 | 0.0002 | 0.0004 | 0.0020 | 0.0012 | 0.0034 | 0.0064 | 0.0225 | 0.0278 | 0.0856 | 0.0911 | 0.1447 | 0.1588 | 0.0900 | 0.0998 | 0.1345 | 0.1395 | 0.5171 | 0.4750 | 0.0006 | 0.0008 | 0.0028 | 0.0201 | 0.0798 | 0.1283 | 0.0907 | 0.1237 | 0.5531 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 609 | | 8337 | 19608 | 101.9 | 24.16 | 175.88 | 142.47 | 73 | 81 | 88 | 94 | 100 | 105 | 112 | 120 | 133 | 0.0523 | 1025 | 1.074 | 109.56 | 38.12 | 1 | 0.0356 | 297 | 0.0033 | 13.03 | 6.018 | 0.3011 | 10963.8 | 1250000 | 150000000 | 19200000000 | 0.4490 | 0.2070 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0097 | 0.0004 | 0.0284 | 0.0036 | 0.0817 | 0.0181 | 0.1470 | 0.0410 | 0.1702 | 0.0513 | 0.1762 | 0.0783 | 0.3842 | 0.8070 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0032 | 0.0002 | 0.0086 | 0.0011 | 0.0365 | 0.0115 | 0.0679 | 0.0245 | 0.0709 | 0.0208 | 0.1034 | 0.0398 | 0.7091 | 0.9020 | 0.0034 | 0.0064 | 0.0135 | 0.0451 | 0.0310 | 0.0579 | 0.1018 | 0.1373 | 0.1415 | 0.1803 | 0.1894 | 0.1717 | 0.1240 | 0.0880 | 0.1388 | 0.1652 | 0.2567 | 0.1481 | 0.0010 | 0.0026 | 0.0126 | 0.0419 | 0.0856 | 0.1309 | 0.1186 | 0.1404 | 0.4663 | 19 | 44 | 74 | 106 | 143 | 186 | 235 | 291 | 376 | 0.0029 | 66.47 | 7.155 | 0.2685 | 51228.7 | 19100000 | 8380000000 | 4150000000000 | 0.4441 | 0.1782 | 0.0134 | 0.0030 | 0.0694 | 0.0074 | 0.1927 | 0.0268 | 0.1717 | 0.0701 | 0.1818 | 0.1554 | 0.1490 | 0.1966 | 0.0920 | 0.1467 | 0.0742 | 0.1533 | 0.0557 | 0.2406 | 0.0008 | 0.0005 | 0.0013 | 0.0013 | 0.0030 | 0.0031 | 0.0128 | 0.0102 | 0.0442 | 0.0384 | 0.0810 | 0.0621 | 0.0713 | 0.0562 | 0.1002 | 0.0808 | 0.6853 | 0.7475 | 0.0015 | 0.0011 | 0.0021 | 0.0051 | 0.0067 | 0.0130 | 0.0204 | 0.0276 | 0.0725 | 0.0848 | 0.1212 | 0.1448 | 0.1025 | 0.1133 | 0.1303 | 0.1466 | 0.5429 | 0.4637 | 0.0005 | 0.0020 | 0.0054 | 0.0154 | 0.0553 | 0.1015 | 0.0850 | 0.1150 | 0.6199 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 484 | 784 | | 7556 | 23389 | 282.7 | 59.70 | 166.78 | 196.60 | 210 | 231 | 247 | 262 | 276 | 293 | 311 | 334 | 366 | 0.0490 | 1145 | 1.213 | 102.16 | 38.05 | 1 | 0.0335 | 253 | 0.0006 | 75.57 | 7.614 | 0.1408 | 83467.9 | 25700000 | 8220000000 | 2730000000000 | 0.4316 | 0.2191 | 0.0002 | 0.0003 | 0.0006 | 0.0001 | 0.0020 | 0.0000 | 0.0170 | 0.0010 | 0.0677 | 0.0158 | 0.1511 | 0.0377 | 0.1521 | 0.0373 | 0.1708 | 0.0609 | 0.4384 | 0.8469 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0056 | 0.0004 | 0.0270 | 0.0106 | 0.0679 | 0.0232 | 0.0670 | 0.0160 | 0.0934 | 0.0265 | 0.7377 | 0.9233 | 0.0044 | 0.0233 | 0.0110 | 0.0233 | 0.0242 | 0.0631 | 0.0696 | 0.1728 | 0.1275 | 0.1960 | 0.1758 | 0.2060 | 0.1231 | 0.1063 | 0.1407 | 0.1296 | 0.3238 | 0.0797 | 0.0012 | 0.0035 | 0.0092 | 0.0372 | 0.0773 | 0.1330 | 0.1108 | 0.1304 | 0.4975 | 13 | 15 | 19 | 28 | 65 | 144 | 233 | 329 | 451 | 0.0382 | 38.04 | 5.638 | 0.4378 | 66466.3 | 34900000 | 21500000000 | 14900000000000 | 0.4729 | 0.1465 | 0.0850 | 0.0014 | 0.2309 | 0.0230 | 0.3225 | 0.1754 | 0.1274 | 0.1961 | 0.0928 | 0.2081 | 0.0531 | 0.1530 | 0.0330 | 0.0985 | 0.0279 | 0.0639 | 0.0274 | 0.0806 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0009 | 0.0009 | 0.0084 | 0.0061 | 0.0473 | 0.0406 | 0.0840 | 0.0716 | 0.0667 | 0.0537 | 0.1009 | 0.0862 | 0.6912 | 0.7406 | 0.0001 | 0.0001 | 0.0013 | 0.0011 | 0.0031 | 0.0056 | 0.0161 | 0.0217 | 0.0677 | 0.0724 | 0.1058 | 0.1268 | 0.0903 | 0.0954 | 0.1290 | 0.1366 | 0.5867 | 0.5403 | 0.0000 | 0.0011 | 0.0013 | 0.0122 | 0.0536 | 0.0968 | 0.0807 | 0.1121 | 0.6423 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 989 | 569 | | 11363 | 17154 | 435.1 | 102.14 | 100.15 | 106.92 | 319 | 350 | 374 | 396 | 420 | 445 | 475 | 519 | 577 | 0.0642 | 1102 | 1.214 | 111.97 | 45.88 | 1 | 0.0259 | 294 | 0.0008 | 45.10 | 7.457 | 0.1791 | 199761.0 | 96800000 | 49400000000 | 26500000000000 | 0.4356 | 0.2162 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0049 | 0.0006 | 0.0187 | 0.0024 | 0.0547 | 0.0168 | 0.1228 | 0.0359 | 0.1224 | 0.0361 | 0.1532 | 0.0537 | 0.5207 | 0.8544 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0001 | 0.0074 | 0.0009 | 0.0262 | 0.0104 | 0.0589 | 0.0186 | 0.0605 | 0.0168 | 0.0788 | 0.0275 | 0.7659 | 0.9258 | 0.0027 | 0.0014 | 0.0063 | 0.0068 | 0.0094 | 0.0315 | 0.0367 | 0.0876 | 0.0823 | 0.1231 | 0.1360 | 0.1737 | 0.0922 | 0.1081 | 0.1128 | 0.1231 | 0.5217 | 0.3447 | 0.0010 | 0.0012 | 0.0068 | 0.0319 | 0.0806 | 0.1097 | 0.0930 | 0.1123 | 0.5635 | 7 | 11 | 20 | 37 | 62 | 94 | 132 | 180 | 248 | 0.0392 | 11.55 | 4.988 | 0.4732 | 21460.8 | 6340000 | 2300000000 | 971000000000 | 0.5515 | 0.1124 | 0.0581 | 0.0039 | 0.2164 | 0.0200 | 0.2885 | 0.1377 | 0.1593 | 0.1383 | 0.1259 | 0.1997 | 0.0867 | 0.1917 | 0.0344 | 0.1180 | 0.0237 | 0.1032 | 0.0070 | 0.0874 | 0.0001 | 0.0001 | 0.0005 | 0.0005 | 0.0012 | 0.0003 | 0.0130 | 0.0092 | 0.0667 | 0.0520 | 0.1087 | 0.0943 | 0.0812 | 0.0656 | 0.1186 | 0.1022 | 0.6099 | 0.6759 | 0.0005 | 0.0012 | 0.0010 | 0.0029 | 0.0045 | 0.0074 | 0.0218 | 0.0286 | 0.0939 | 0.1036 | 0.1590 | 0.1785 | 0.0997 | 0.1088 | 0.1431 | 0.1573 | 0.4763 | 0.4118 | 0.0003 | 0.0006 | 0.0018 | 0.0174 | 0.0781 | 0.1316 | 0.0944 | 0.1376 | 0.5381 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 203 | 497 | | 8616 | 14575 | 174.6 | 44.13 | 171.91 | 149.45 | 122 | 138 | 150 | 161 | 171 | 181 | 192 | 207 | 232 | 0.0673 | 981 | 1.044 | 125.32 | 34.48 | 1 | 0.0331 | 285 | 0.0012 | 38.52 | 7.056 | 0.1977 | 32427.2 | 6400000 | 1340000000 | 300000000000 | 0.4569 | 0.1989 | 0.0000 | 0.0000 | 0.0017 | 0.0001 | 0.0078 | 0.0003 | 0.0287 | 0.0031 | 0.0888 | 0.0227 | 0.1586 | 0.0483 | 0.1617 | 0.0556 | 0.1808 | 0.0817 | 0.3720 | 0.7881 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0011 | 0.0383 | 0.0140 | 0.0683 | 0.0253 | 0.0693 | 0.0240 | 0.0973 | 0.0396 | 0.7154 | 0.8960 | 0.0043 | 0.0068 | 0.0129 | 0.0307 | 0.0302 | 0.0341 | 0.0851 | 0.1022 | 0.1424 | 0.1959 | 0.1763 | 0.1959 | 0.1128 | 0.1141 | 0.1375 | 0.1210 | 0.2984 | 0.1993 | 0.0015 | 0.0050 | 0.0118 | 0.0350 | 0.0866 | 0.1316 | 0.1178 | 0.1480 | 0.4626 | 22 | 43 | 68 | 99 | 135 | 170 | 218 | 279 | 376 | 0.0026 | 76.94 | 7.156 | 0.2520 | 51884.8 | 21400000 | 11000000000 | 6610000000000 | 0.4445 | 0.1894 | 0.0210 | 0.0006 | 0.0998 | 0.0058 | 0.1884 | 0.0378 | 0.1768 | 0.0812 | 0.1748 | 0.1518 | 0.1509 | 0.1963 | 0.0944 | 0.1541 | 0.0536 | 0.1491 | 0.0404 | 0.2232 | 0.0008 | 0.0002 | 0.0013 | 0.0005 | 0.0043 | 0.0019 | 0.0145 | 0.0096 | 0.0545 | 0.0413 | 0.1088 | 0.0813 | 0.0850 | 0.0660 | 0.1138 | 0.0944 | 0.6169 | 0.7048 | 0.0008 | 0.0011 | 0.0042 | 0.0066 | 0.0085 | 0.0130 | 0.0307 | 0.0414 | 0.0827 | 0.0900 | 0.1433 | 0.1572 | 0.1056 | 0.1118 | 0.1272 | 0.1359 | 0.4970 | 0.4431 | 0.0005 | 0.0029 | 0.0095 | 0.0225 | 0.0731 | 0.1165 | 0.1001 | 0.1229 | 0.5519 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 241 | 848 | | 10173 | 33400 | 558.7 | 106.36 | 141.20 | 210.07 | 440 | 469 | 494 | 517 | 539 | 564 | 595 | 638 | 721 | 0.0340 | 1136 | 1.181 | 125.88 | 48.08 | 1 | 0.0321 | 327 | 0.0010 | 33.71 | 7.169 | 0.1994 | 323447.0 | 194000000 | 121000000000 | 78500000000000 | 0.3999 | 0.2475 | 0.0004 | 0.0002 | 0.0009 | 0.0001 | 0.0027 | 0.0002 | 0.0123 | 0.0021 | 0.0344 | 0.0148 | 0.0701 | 0.0282 | 0.0822 | 0.0219 | 0.1201 | 0.0283 | 0.6769 | 0.9042 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0077 | 0.0002 | 0.0193 | 0.0092 | 0.0401 | 0.0151 | 0.0464 | 0.0088 | 0.0651 | 0.0146 | 0.8195 | 0.9521 | 0.0060 | 0.0020 | 0.0079 | 0.0101 | 0.0113 | 0.0061 | 0.0344 | 0.0869 | 0.0656 | 0.1212 | 0.0947 | 0.2222 | 0.0742 | 0.1253 | 0.0947 | 0.1616 | 0.6113 | 0.2646 | 0.0019 | 0.0063 | 0.0137 | 0.0288 | 0.0574 | 0.1020 | 0.0876 | 0.1004 | 0.6019 | 7 | 9 | 12 | 16 | 31 | 71 | 144 | 264 | 446 | 0.0759 | 52.63 | 5.308 | 0.4892 | 64064.9 | 41000000 | 31800000000 | 28400000000000 | 0.3985 | 0.2299 | 0.1332 | 0.0028 | 0.3108 | 0.0481 | 0.2982 | 0.2452 | 0.1039 | 0.2139 | 0.0716 | 0.1845 | 0.0484 | 0.1328 | 0.0222 | 0.0737 | 0.0081 | 0.0576 | 0.0035 | 0.0413 | 0.0002 | 0.0002 | 0.0008 | 0.0002 | 0.0013 | 0.0007 | 0.0107 | 0.0085 | 0.0677 | 0.0583 | 0.1067 | 0.0940 | 0.0684 | 0.0620 | 0.1038 | 0.0989 | 0.6404 | 0.6771 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0018 | 0.0038 | 0.0161 | 0.0195 | 0.0838 | 0.0907 | 0.1222 | 0.1354 | 0.0813 | 0.0869 | 0.1259 | 0.1305 | 0.5681 | 0.5326 | 0.0003 | 0.0006 | 0.0013 | 0.0134 | 0.0759 | 0.1150 | 0.0717 | 0.1123 | 0.6096 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 619 | 317 | | 7410 | 29983 | 364.7 | 86.29 | 152.06 | 265.97 | 260 | 289 | 313 | 336 | 358 | 380 | 405 | 434 | 477 | 0.0351 | 1051 | 1.206 | 108.37 | 43.84 | 1 | 0.0379 | 281 | 0.0006 | 87.06 | 7.645 | 0.1436 | 140416.0 | 57000000 | 24300000000 | 10900000000000 | 0.4464 | 0.2073 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0086 | 0.0001 | 0.0271 | 0.0018 | 0.0873 | 0.0187 | 0.1534 | 0.0482 | 0.1532 | 0.0439 | 0.1846 | 0.0654 | 0.3836 | 0.8218 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0081 | 0.0003 | 0.0365 | 0.0110 | 0.0711 | 0.0286 | 0.0684 | 0.0204 | 0.0949 | 0.0311 | 0.7198 | 0.9085 | 0.0050 | 0.0092 | 0.0093 | 0.0297 | 0.0328 | 0.0343 | 0.0734 | 0.0847 | 0.1290 | 0.1533 | 0.1917 | 0.2197 | 0.1226 | 0.1327 | 0.1347 | 0.1373 | 0.3015 | 0.1991 | 0.0006 | 0.0026 | 0.0110 | 0.0266 | 0.0747 | 0.1389 | 0.1155 | 0.1259 | 0.5043 | 7 | 9 | 11 | 13 | 20 | 43 | 110 | 258 | 517 | 0.1512 | 39.36 | 4.482 | 0.5817 | 93855.6 | 84800000 | 94200000000 | 120000000000000 | 0.4152 | 0.1980 | 0.0734 | 0.0021 | 0.2052 | 0.0259 | 0.2539 | 0.1687 | 0.1640 | 0.1542 | 0.1373 | 0.1932 | 0.0879 | 0.1763 | 0.0480 | 0.1107 | 0.0165 | 0.0824 | 0.0137 | 0.0866 | 0.0000 | 0.0002 | 0.0007 | 0.0005 | 0.0021 | 0.0003 | 0.0100 | 0.0059 | 0.0491 | 0.0469 | 0.0856 | 0.0756 | 0.0537 | 0.0477 | 0.0753 | 0.0702 | 0.7236 | 0.7526 | 0.0003 | 0.0001 | 0.0018 | 0.0006 | 0.0017 | 0.0025 | 0.0090 | 0.0096 | 0.0589 | 0.0634 | 0.0991 | 0.1035 | 0.0632 | 0.0706 | 0.0877 | 0.0978 | 0.6783 | 0.6519 | 0.0001 | 0.0011 | 0.0020 | 0.0119 | 0.0542 | 0.0904 | 0.0605 | 0.0819 | 0.6977 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 592 | 447 | | 14268 | 31171 | 276.5 | 63.92 | 156.47 | 200.54 | 198 | 221 | 239 | 256 | 272 | 288 | 306 | 329 | 363 | 0.0479 | 1493 | 1.112 | 122.50 | 42.44 | 2 | 0.0226 | 322 | 0.0005 | 82.25 | 7.811 | 0.1476 | 80557.2 | 24600000 | 7880000000 | 2630000000000 | 0.4955 | 0.1599 | 0.0002 | 0.0001 | 0.0005 | 0.0001 | 0.0060 | 0.0004 | 0.0222 | 0.0013 | 0.0747 | 0.0210 | 0.1425 | 0.0397 | 0.1357 | 0.0415 | 0.1626 | 0.0645 | 0.4556 | 0.8315 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0051 | 0.0007 | 0.0308 | 0.0126 | 0.0628 | 0.0213 | 0.0597 | 0.0187 | 0.0832 | 0.0292 | 0.7574 | 0.9174 | 0.0026 | 0.0113 | 0.0079 | 0.0213 | 0.0229 | 0.0464 | 0.0649 | 0.1004 | 0.1302 | 0.1757 | 0.1868 | 0.2045 | 0.1028 | 0.1142 | 0.1388 | 0.1380 | 0.3432 | 0.1882 | 0.0004 | 0.0016 | 0.0070 | 0.0240 | 0.0851 | 0.1323 | 0.0987 | 0.1321 | 0.5187 | 11 | 14 | 18 | 26 | 57 | 113 | 187 | 292 | 453 | 0.0385 | 36.22 | 5.629 | 0.4704 | 64696.1 | 37000000 | 25200000000 | 19300000000000 | 0.4742 | 0.1836 | 0.0255 | 0.0014 | 0.1594 | 0.0110 | 0.2636 | 0.0618 | 0.1760 | 0.1240 | 0.1590 | 0.2011 | 0.1042 | 0.2139 | 0.0552 | 0.1298 | 0.0320 | 0.1236 | 0.0251 | 0.1333 | 0.0001 | 0.0001 | 0.0011 | 0.0007 | 0.0017 | 0.0016 | 0.0083 | 0.0060 | 0.0509 | 0.0418 | 0.0820 | 0.0672 | 0.0623 | 0.0538 | 0.0920 | 0.0797 | 0.7017 | 0.7491 | 0.0003 | 0.0008 | 0.0022 | 0.0016 | 0.0045 | 0.0054 | 0.0174 | 0.0185 | 0.0624 | 0.0667 | 0.0988 | 0.1125 | 0.0795 | 0.0787 | 0.1028 | 0.1074 | 0.6320 | 0.6083 | 0.0001 | 0.0006 | 0.0031 | 0.0120 | 0.0572 | 0.0936 | 0.0702 | 0.0963 | 0.6669 |