High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 875 | 62 | 1334 | 3820 | 91.9 | 21.30 | 105.54 | 80.69 | 68 | 74 | 80 | 85 | 90 | 95 | 100 | 106 | 117 | 0.1102 | 421 | 0.866 | 95.82 | 24.17 | 1 | 0.1807 | 241 | 0.0026 | 28.10 | 6.166 | 0.2282 | 8892.5 | 911642 | 99600000 | 11700000000 | 0.4476 | 0.2105 | 0.0034 | 0.0000 | 0.0056 | 0.0000 | 0.0213 | 0.0048 | 0.0369 | 0.0081 | 0.0884 | 0.0306 | 0.1432 | 0.0564 | 0.1454 | 0.0596 | 0.1946 | 0.0854 | 0.3613 | 0.7550 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0000 | 0.0157 | 0.0023 | 0.0507 | 0.0235 | 0.1005 | 0.0454 | 0.0811 | 0.0310 | 0.1180 | 0.0613 | 0.6267 | 0.8365 | 0.0419 | 0.0125 | 0.0366 | 0.0375 | 0.0628 | 0.1000 | 0.0785 | 0.1000 | 0.1937 | 0.2125 | 0.2042 | 0.1000 | 0.0628 | 0.0750 | 0.0995 | 0.1375 | 0.2199 | 0.2250 | 0.0016 | 0.0128 | 0.0096 | 0.0465 | 0.1348 | 0.1750 | 0.1236 | 0.1637 | 0.3323 | 28 | 40 | 52 | 68 | 85 | 105 | 126 | 153 | 212 | 0.0130 | 7.64 | 5.068 | 0.4624 | 17649.0 | 4150000 | 1240000000 | 442000000000 | 0.4801 | 0.1727 | 0.0158 | 0.0013 | 0.0706 | 0.0076 | 0.1364 | 0.0297 | 0.1583 | 0.0607 | 0.1754 | 0.1208 | 0.1851 | 0.1720 | 0.1218 | 0.1562 | 0.0938 | 0.1720 | 0.0426 | 0.2796 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0067 | 0.0050 | 0.0249 | 0.0184 | 0.0716 | 0.0537 | 0.1095 | 0.0910 | 0.0851 | 0.0746 | 0.1183 | 0.1065 | 0.5817 | 0.6491 | 0.0036 | 0.0062 | 0.0099 | 0.0075 | 0.0172 | 0.0249 | 0.0506 | 0.0634 | 0.1112 | 0.1045 | 0.1546 | 0.1505 | 0.1103 | 0.1256 | 0.1338 | 0.1381 | 0.4087 | 0.3794 | 0.0013 | 0.0072 | 0.0118 | 0.0301 | 0.0740 | 0.1382 | 0.0950 | 0.1434 | 0.4990 | |
MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 827 | 97 | 4779 | 9869 | 431.6 | 72.01 | 52.87 | 95.06 | 321 | 371 | 401 | 423 | 444 | 465 | 484 | 498 | 512 | 0.0808 | 797 | 0.816 | 113.09 | 23.00 | 3 | 0.0515 | 246 | 0.0015 | 19.21 | 6.788 | 0.2616 | 191443.0 | 86800000 | 40100000000 | 18800000000000 | 0.4012 | 0.2344 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0004 | 0.0072 | 0.0011 | 0.0289 | 0.0142 | 0.0520 | 0.0223 | 0.0494 | 0.0161 | 0.0921 | 0.0212 | 0.7664 | 0.9247 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0004 | 0.0024 | 0.0011 | 0.0169 | 0.0142 | 0.0276 | 0.0223 | 0.0203 | 0.0161 | 0.0286 | 0.0212 | 0.9034 | 0.9247 | 0.0406 | 0.0000 | 0.0406 | 0.0000 | 0.0969 | 0.0000 | 0.1031 | 0.0000 | 0.1406 | 0.0000 | 0.1875 | 0.0000 | 0.1125 | 0.0000 | 0.1188 | 0.0000 | 0.1594 | 0.0000 | 0.0026 | 0.0015 | 0.0060 | 0.0139 | 0.0285 | 0.0490 | 0.0401 | 0.0487 | 0.8098 | 5 | 6 | 8 | 9 | 10 | 13 | 28 | 75 | 177 | 0.2057 | 10.66 | 3.527 | 0.6733 | 11831.5 | 4010000 | 1640000000 | 755000000000 | 0.4322 | 0.1951 | 0.0842 | 0.0023 | 0.1811 | 0.0240 | 0.2704 | 0.1244 | 0.1505 | 0.1210 | 0.1505 | 0.2237 | 0.1148 | 0.1872 | 0.0332 | 0.1016 | 0.0128 | 0.1062 | 0.0026 | 0.1096 | 0.0000 | 0.0000 | 0.0020 | 0.0007 | 0.0032 | 0.0060 | 0.0134 | 0.0112 | 0.0512 | 0.0417 | 0.0721 | 0.0684 | 0.0473 | 0.0407 | 0.0776 | 0.0691 | 0.7333 | 0.7622 | 0.0005 | 0.0005 | 0.0014 | 0.0015 | 0.0061 | 0.0051 | 0.0182 | 0.0243 | 0.0634 | 0.0694 | 0.0895 | 0.0861 | 0.0541 | 0.0597 | 0.0848 | 0.0891 | 0.6822 | 0.6643 | 0.0009 | 0.0017 | 0.0021 | 0.0167 | 0.0541 | 0.0824 | 0.0558 | 0.0815 | 0.7048 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 404 | 381 | 364 | 11109 | 91.1 | 12.14 | 8.23 | 2.31 | 76 | 80 | 84 | 87 | 91 | 94 | 97 | 101 | 107 | 0.0564 | 627 | 0.370 | 126.83 | 26.31 | 1 | 1.2060 | 439 | 0.0718 | 0.71 | 2.815 | 0.7088 | 8437.9 | 795470 | 76300000 | 7430000000 | 0.3908 | 0.2100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0192 | 0.0055 | 0.0895 | 0.0714 | 0.1789 | 0.1099 | 0.1278 | 0.0604 | 0.1917 | 0.1044 | 0.3930 | 0.6484 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0117 | 0.0055 | 0.0787 | 0.0714 | 0.1254 | 0.1099 | 0.0671 | 0.0604 | 0.1195 | 0.1044 | 0.5977 | 0.6484 | 0.0333 | 0.0000 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.1333 | 0.0000 | 0.2000 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.0055 | 0.0055 | 0.0055 | 0.0546 | 0.1421 | 0.1694 | 0.1038 | 0.1639 | 0.3497 | 5 | 6 | 7 | 8 | 8 | 9 | 9 | 10 | 11 | 0.2651 | 0.45 | 1.038 | 0.6298 | 73.1 | 692.301 | 6934.55 | 73026.4 | 0.5150 | 0.1470 | 0.0084 | 0.0000 | 0.0454 | 0.0006 | 0.1209 | 0.0027 | 0.2055 | 0.0101 | 0.2489 | 0.0293 | 0.2133 | 0.0743 | 0.1150 | 0.1788 | 0.0368 | 0.3510 | 0.0059 | 0.3532 | 0.0002 | 0.0000 | 0.0024 | 0.0000 | 0.0090 | 0.0002 | 0.0345 | 0.0025 | 0.0902 | 0.0128 | 0.1613 | 0.0328 | 0.2251 | 0.0673 | 0.2757 | 0.2320 | 0.2014 | 0.6524 | 0.0871 | 0.3913 | 0.1762 | 0.3337 | 0.2103 | 0.1554 | 0.1847 | 0.0633 | 0.1500 | 0.0368 | 0.1089 | 0.0161 | 0.0537 | 0.0035 | 0.0237 | 0.0000 | 0.0054 | 0.0000 | 0.0034 | 0.0150 | 0.0465 | 0.1072 | 0.1765 | 0.2248 | 0.1975 | 0.1520 | 0.0770 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1163 | 489 | 321 | 5383 | 116.6 | 17.58 | 10.59 | 16.86 | 93 | 99 | 105 | 110 | 115 | 122 | 128 | 133 | 140 | 0.0832 | 448 | 1.174 | 34.48 | 13.89 | 3 | 0.2897 | 93 | 0.0412 | 1.34 | 3.375 | 0.6192 | 13896.5 | 1690000 | 210000000 | 26600000000 | 0.3932 | 0.2232 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0388 | 0.0156 | 0.0930 | 0.0498 | 0.1395 | 0.1090 | 0.1395 | 0.0592 | 0.1938 | 0.0935 | 0.3837 | 0.6729 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0243 | 0.0156 | 0.0590 | 0.0498 | 0.1007 | 0.1090 | 0.0833 | 0.0592 | 0.1111 | 0.0935 | 0.6146 | 0.6729 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.1000 | 0.0000 | 0.1000 | 0.0000 | 0.0333 | 0.0000 | 0.0000 | 0.0000 | 0.0258 | 0.0516 | 0.0839 | 0.1290 | 0.0710 | 0.1032 | 0.5355 | 3 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 13 | 0.1037 | 0.50 | 1.327 | 0.4010 | 396.2 | 39837.1 | 5690000 | 976000000 | 0.5867 | 0.1158 | 0.1081 | 0.0234 | 0.1521 | 0.0646 | 0.1822 | 0.1055 | 0.1683 | 0.1248 | 0.1992 | 0.1564 | 0.1228 | 0.1745 | 0.0533 | 0.1681 | 0.0139 | 0.1293 | 0.0000 | 0.0533 | 0.0717 | 0.0199 | 0.1019 | 0.0545 | 0.1150 | 0.0857 | 0.0980 | 0.0980 | 0.1194 | 0.1193 | 0.1073 | 0.1330 | 0.0772 | 0.1375 | 0.0728 | 0.1248 | 0.2366 | 0.2273 | 0.0433 | 0.0158 | 0.0226 | 0.0204 | 0.0377 | 0.0226 | 0.0377 | 0.0385 | 0.0734 | 0.0973 | 0.1092 | 0.1154 | 0.0923 | 0.0905 | 0.1224 | 0.1222 | 0.4614 | 0.4774 | 0.1188 | 0.1103 | 0.0827 | 0.0562 | 0.0615 | 0.0679 | 0.0679 | 0.0933 | 0.3415 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 287 | 208 | 5091 | 12471 | 474.1 | 73.02 | 68.38 | 135.66 | 363 | 414 | 452 | 475 | 490 | 504 | 518 | 533 | 553 | 0.0763 | 952 | 1.174 | 64.62 | 19.85 | 1 | 0.0297 | 151 | 0.0020 | 19.65 | 6.571 | 0.2736 | 230087.0 | 114000000 | 57200000000 | 29100000000000 | 0.4330 | 0.2034 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0074 | 0.0012 | 0.0203 | 0.0121 | 0.0432 | 0.0234 | 0.0404 | 0.0127 | 0.0650 | 0.0183 | 0.8215 | 0.9322 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0032 | 0.0012 | 0.0131 | 0.0121 | 0.0257 | 0.0234 | 0.0181 | 0.0127 | 0.0235 | 0.0183 | 0.9163 | 0.9322 | 0.0328 | 0.0000 | 0.0615 | 0.0000 | 0.1025 | 0.0000 | 0.1311 | 0.0000 | 0.1352 | 0.0000 | 0.1352 | 0.0000 | 0.1230 | 0.0000 | 0.0820 | 0.0000 | 0.1967 | 0.0000 | 0.0000 | 0.0026 | 0.0065 | 0.0091 | 0.0308 | 0.0587 | 0.0532 | 0.0834 | 0.7557 | 6 | 8 | 9 | 11 | 15 | 21 | 36 | 71 | 216 | 0.1260 | 12.46 | 3.408 | 0.6217 | 23078.9 | 13100000 | 9690000000 | 8870000000000 | 0.4949 | 0.1599 | 0.0417 | 0.0057 | 0.1106 | 0.0278 | 0.1571 | 0.0785 | 0.1234 | 0.0849 | 0.1619 | 0.1091 | 0.1250 | 0.1320 | 0.1106 | 0.1084 | 0.1090 | 0.1434 | 0.0609 | 0.3103 | 0.0024 | 0.0014 | 0.0044 | 0.0028 | 0.0051 | 0.0068 | 0.0139 | 0.0160 | 0.0493 | 0.0376 | 0.0748 | 0.0673 | 0.0479 | 0.0450 | 0.0816 | 0.0730 | 0.7206 | 0.7501 | 0.0000 | 0.0014 | 0.0017 | 0.0009 | 0.0043 | 0.0047 | 0.0181 | 0.0161 | 0.0513 | 0.0584 | 0.0945 | 0.1011 | 0.0513 | 0.0570 | 0.0815 | 0.0783 | 0.6972 | 0.6820 | 0.0008 | 0.0012 | 0.0043 | 0.0152 | 0.0519 | 0.0831 | 0.0542 | 0.0807 | 0.7087 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 923 | 749 | 18485 | 19144 | 337.4 | 48.91 | 148.53 | 162.19 | 268 | 300 | 318 | 331 | 344 | 355 | 367 | 380 | 396 | 0.0705 | 1349 | 1.142 | 100.72 | 39.20 | 2 | 0.0147 | 271 | 0.0025 | 9.90 | 6.327 | 0.3429 | 116234.0 | 40800000 | 14500000000 | 5230000000000 | 0.4218 | 0.2181 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0027 | 0.0001 | 0.0083 | 0.0008 | 0.0174 | 0.0071 | 0.0285 | 0.0145 | 0.0316 | 0.0074 | 0.0551 | 0.0119 | 0.8546 | 0.9581 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0001 | 0.0022 | 0.0008 | 0.0085 | 0.0071 | 0.0136 | 0.0145 | 0.0122 | 0.0074 | 0.0186 | 0.0119 | 0.9443 | 0.9581 | 0.0326 | 0.0000 | 0.0692 | 0.0000 | 0.0794 | 0.0000 | 0.1090 | 0.0000 | 0.1517 | 0.0000 | 0.1415 | 0.0000 | 0.1395 | 0.0000 | 0.1446 | 0.0000 | 0.1324 | 0.0000 | 0.0028 | 0.0050 | 0.0091 | 0.0138 | 0.0293 | 0.0412 | 0.0457 | 0.0737 | 0.7793 | 23 | 31 | 42 | 57 | 77 | 109 | 167 | 256 | 387 | 0.0183 | 13.36 | 5.441 | 0.5104 | 48364.8 | 22700000 | 12800000000 | 8140000000000 | 0.3890 | 0.2609 | 0.0233 | 0.0013 | 0.0952 | 0.0085 | 0.1700 | 0.0530 | 0.1578 | 0.1011 | 0.1966 | 0.1512 | 0.1445 | 0.1702 | 0.0908 | 0.1386 | 0.0714 | 0.1404 | 0.0504 | 0.2358 | 0.0001 | 0.0003 | 0.0008 | 0.0009 | 0.0026 | 0.0044 | 0.0128 | 0.0124 | 0.0492 | 0.0417 | 0.0708 | 0.0661 | 0.0547 | 0.0448 | 0.0827 | 0.0706 | 0.7262 | 0.7587 | 0.0007 | 0.0006 | 0.0009 | 0.0017 | 0.0035 | 0.0058 | 0.0196 | 0.0235 | 0.0581 | 0.0707 | 0.0989 | 0.0946 | 0.0629 | 0.0773 | 0.0941 | 0.1006 | 0.6612 | 0.6252 | 0.0000 | 0.0010 | 0.0043 | 0.0159 | 0.0522 | 0.0864 | 0.0570 | 0.0870 | 0.6963 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 838 | 827 | 348 | 3785 | 69.6 | 9.59 | 7.19 | 2.56 | 58 | 61 | 63 | 66 | 69 | 71 | 74 | 78 | 83 | 0.1007 | 381 | 1.208 | 26.48 | 9.85 | 4 | 0.2011 | 70 | 0.0757 | 0.82 | 2.819 | 0.6940 | 4931.9 | 356260 | 26200000 | 1970000000 | 0.3634 | 0.2597 | 0.0033 | 0.0000 | 0.0100 | 0.0000 | 0.0133 | 0.0029 | 0.0332 | 0.0144 | 0.0698 | 0.0720 | 0.0997 | 0.0778 | 0.1096 | 0.0692 | 0.2359 | 0.1268 | 0.4252 | 0.6369 | 0.0030 | 0.0000 | 0.0000 | 0.0000 | 0.0090 | 0.0029 | 0.0181 | 0.0144 | 0.0633 | 0.0690 | 0.0843 | 0.0776 | 0.0663 | 0.0690 | 0.1506 | 0.1149 | 0.6054 | 0.6523 | 0.0323 | 1.0000 | 0.0000 | 0.0000 | 0.1613 | 0.0000 | 0.2258 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.1935 | 0.0000 | 0.1290 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0062 | 0.0247 | 0.0988 | 0.1358 | 0.1420 | 0.1235 | 0.1728 | 0.2840 | 4 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 0.0188 | 7.92 | 4.396 | 0.3583 | 58.2 | 526.12 | 5258.33 | 57582.2 | 0.4841 | 0.1761 | 0.0222 | 0.0039 | 0.0672 | 0.0054 | 0.1627 | 0.0219 | 0.2267 | 0.0409 | 0.2391 | 0.0828 | 0.1725 | 0.1441 | 0.0826 | 0.2539 | 0.0246 | 0.3015 | 0.0025 | 0.1456 | 0.0046 | 0.0003 | 0.0185 | 0.0006 | 0.0490 | 0.0059 | 0.0817 | 0.0178 | 0.1214 | 0.0422 | 0.1762 | 0.0716 | 0.1689 | 0.1446 | 0.1823 | 0.2904 | 0.1974 | 0.4267 | 0.1226 | 0.1623 | 0.1493 | 0.1451 | 0.1143 | 0.1019 | 0.1184 | 0.1036 | 0.0917 | 0.0829 | 0.0937 | 0.0760 | 0.0814 | 0.0864 | 0.0937 | 0.1330 | 0.1349 | 0.1088 | 0.0153 | 0.0463 | 0.0769 | 0.1084 | 0.1441 | 0.1724 | 0.1585 | 0.1298 | 0.1483 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1133 | 155 | 893 | 1399 | 15.3 | 5.59 | 6.05 | 2.57 | 9 | 11 | 12 | 13 | 14 | 15 | 17 | 19 | 23 | 0.2437 | 341 | 0.631 | 86.21 | 19.03 | 0 | 0.2520 | 225 | 0.0063 | 15.00 | 5.353 | 0.2862 | 266.3 | 5252.12 | 117067 | 2910000 | 0.3793 | 0.2519 | 0.0048 | 0.0028 | 0.0333 | 0.0000 | 0.0643 | 0.0127 | 0.1452 | 0.0325 | 0.1786 | 0.0734 | 0.2262 | 0.0805 | 0.1762 | 0.1427 | 0.1143 | 0.2260 | 0.0571 | 0.4294 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0240 | 0.0059 | 0.0314 | 0.0202 | 0.0569 | 0.0308 | 0.0883 | 0.0403 | 0.1033 | 0.0664 | 0.1856 | 0.1151 | 0.4985 | 0.7212 | 0.0282 | 0.0444 | 0.0726 | 0.0667 | 0.0565 | 0.0963 | 0.0645 | 0.1037 | 0.1089 | 0.0889 | 0.1089 | 0.0963 | 0.1089 | 0.1185 | 0.1573 | 0.1481 | 0.2944 | 0.2370 | 0.0070 | 0.0282 | 0.0446 | 0.0845 | 0.1009 | 0.1056 | 0.1502 | 0.1291 | 0.3498 | 2 | 4 | 4 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0207 | 14.14 | 4.219 | 0.3005 | 43.2 | 342.525 | 2947.43 | 27112.9 | 0.5136 | 0.1528 | 0.0287 | 0.0010 | 0.1396 | 0.0117 | 0.2199 | 0.0321 | 0.2581 | 0.0884 | 0.1893 | 0.1574 | 0.1090 | 0.2235 | 0.0402 | 0.2673 | 0.0134 | 0.1720 | 0.0019 | 0.0466 | 0.0022 | 0.0000 | 0.0151 | 0.0048 | 0.0635 | 0.0032 | 0.1389 | 0.0415 | 0.2099 | 0.0909 | 0.2196 | 0.1085 | 0.2056 | 0.1699 | 0.1044 | 0.2759 | 0.0409 | 0.3054 | 0.1010 | 0.3289 | 0.2241 | 0.3156 | 0.1946 | 0.2089 | 0.1749 | 0.0800 | 0.1626 | 0.0444 | 0.0788 | 0.0222 | 0.0542 | 0.0000 | 0.0099 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0320 | 0.0959 | 0.1337 | 0.2024 | 0.2237 | 0.1787 | 0.0959 | 0.0296 | |
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 125 | 813 | 4044 | 8852 | 602.6 | 91.52 | 41.19 | 63.75 | 467 | 546 | 581 | 603 | 621 | 637 | 653 | 670 | 697 | 0.0916 | 811 | 0.861 | 103.18 | 25.63 | 4 | 0.0601 | 243 | 0.0019 | 32.85 | 6.649 | 0.2422 | 371488.0 | 233000000 | 149000000000 | 95900000000000 | 0.4344 | 0.2018 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0008 | 0.0262 | 0.0168 | 0.0455 | 0.0300 | 0.0385 | 0.0173 | 0.0691 | 0.0297 | 0.8172 | 0.9055 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0008 | 0.0201 | 0.0167 | 0.0321 | 0.0289 | 0.0201 | 0.0157 | 0.0338 | 0.0282 | 0.8928 | 0.9097 | 0.0279 | 0.0000 | 0.0391 | 0.0000 | 0.0615 | 0.1429 | 0.1006 | 0.2857 | 0.1006 | 0.2857 | 0.1564 | 0.2857 | 0.1229 | 0.0000 | 0.0950 | 0.0000 | 0.2961 | 0.0000 | 0.0008 | 0.0021 | 0.0062 | 0.0181 | 0.0402 | 0.0743 | 0.0812 | 0.0952 | 0.6820 | 9 | 11 | 14 | 16 | 19 | 24 | 32 | 45 | 88 | 0.0559 | 3.74 | 3.856 | 0.6364 | 5760.6 | 1520000 | 505000000 | 191000000000 | 0.4879 | 0.1680 | 0.0222 | 0.0179 | 0.0677 | 0.0335 | 0.0812 | 0.0288 | 0.1141 | 0.0594 | 0.1460 | 0.0957 | 0.1470 | 0.0868 | 0.1692 | 0.1094 | 0.1335 | 0.1627 | 0.1190 | 0.4059 | 0.0058 | 0.0099 | 0.0173 | 0.0192 | 0.0142 | 0.0128 | 0.0242 | 0.0271 | 0.0468 | 0.0434 | 0.0560 | 0.0449 | 0.0629 | 0.0545 | 0.0844 | 0.0813 | 0.6884 | 0.7067 | 0.0032 | 0.0069 | 0.0153 | 0.0122 | 0.0159 | 0.0130 | 0.0312 | 0.0298 | 0.0503 | 0.0519 | 0.0751 | 0.0833 | 0.0649 | 0.0596 | 0.0808 | 0.0795 | 0.6635 | 0.6639 | 0.0049 | 0.0113 | 0.0157 | 0.0300 | 0.0458 | 0.0679 | 0.0684 | 0.0915 | 0.6644 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 844 | 2908 | 15413 | 16.0 | 5.68 | 6.17 | 2.21 | 10 | 12 | 13 | 14 | 15 | 16 | 18 | 19 | 22 | 0.0804 | 1239 | 1.278 | 24.04 | 7.81 | 0 | 0.0193 | 56 | 0.0081 | 8.98 | 5.211 | 0.3653 | 289.8 | 6020.69 | 146883 | 4220000 | 0.4199 | 0.2102 | 0.0085 | 0.0004 | 0.0216 | 0.0036 | 0.0385 | 0.0085 | 0.0745 | 0.0222 | 0.1137 | 0.0287 | 0.1476 | 0.0534 | 0.2149 | 0.0825 | 0.2097 | 0.1756 | 0.1711 | 0.6250 | 0.0052 | 0.0000 | 0.0124 | 0.0018 | 0.0204 | 0.0040 | 0.0261 | 0.0141 | 0.0461 | 0.0196 | 0.0518 | 0.0236 | 0.0969 | 0.0460 | 0.1330 | 0.0873 | 0.6081 | 0.8036 | 0.0279 | 0.0590 | 0.0540 | 0.0729 | 0.0714 | 0.0521 | 0.0976 | 0.0486 | 0.1063 | 0.0972 | 0.0871 | 0.1632 | 0.1080 | 0.1042 | 0.1307 | 0.1250 | 0.3171 | 0.2778 | 0.0127 | 0.0202 | 0.0254 | 0.0419 | 0.0538 | 0.0695 | 0.1046 | 0.1674 | 0.5045 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0174 | 10.89 | 4.353 | 0.3184 | 42.9 | 326.59 | 2675.72 | 23343.4 | 0.5105 | 0.1490 | 0.0093 | 0.0007 | 0.0467 | 0.0029 | 0.1332 | 0.0168 | 0.2261 | 0.0557 | 0.2649 | 0.1187 | 0.2015 | 0.1957 | 0.0932 | 0.2556 | 0.0225 | 0.2405 | 0.0026 | 0.1134 | 0.0005 | 0.0000 | 0.0014 | 0.0005 | 0.0117 | 0.0029 | 0.0395 | 0.0124 | 0.0975 | 0.0337 | 0.1985 | 0.0723 | 0.2678 | 0.1849 | 0.2578 | 0.3562 | 0.1253 | 0.3371 | 0.1026 | 0.2983 | 0.2437 | 0.3365 | 0.2794 | 0.2278 | 0.2269 | 0.0988 | 0.1028 | 0.0292 | 0.0369 | 0.0090 | 0.0071 | 0.0004 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0196 | 0.0575 | 0.1217 | 0.1919 | 0.2514 | 0.2092 | 0.1174 | 0.0298 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 349 | 807 | 6538 | 12626 | 588.0 | 86.69 | 128.31 | 222.66 | 469 | 530 | 562 | 584 | 602 | 620 | 637 | 657 | 683 | 0.0673 | 850 | 0.775 | 146.56 | 30.15 | 1 | 0.0509 | 333 | 0.0010 | 44.42 | 7.238 | 0.1938 | 353259.0 | 216000000 | 134000000000 | 83900000000000 | 0.4229 | 0.2180 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0002 | 0.0197 | 0.0106 | 0.0355 | 0.0173 | 0.0365 | 0.0112 | 0.0673 | 0.0176 | 0.8370 | 0.9433 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0129 | 0.0106 | 0.0221 | 0.0173 | 0.0201 | 0.0112 | 0.0312 | 0.0176 | 0.9121 | 0.9433 | 0.0276 | 0.0000 | 0.0379 | 0.0000 | 0.0379 | 0.0000 | 0.1241 | 0.0000 | 0.1310 | 0.0000 | 0.1586 | 0.0000 | 0.1241 | 0.0000 | 0.0931 | 0.0000 | 0.2655 | 0.0000 | 0.0011 | 0.0034 | 0.0053 | 0.0169 | 0.0344 | 0.0573 | 0.0655 | 0.0922 | 0.7238 | 11 | 13 | 16 | 21 | 29 | 46 | 87 | 188 | 404 | 0.1397 | 11.93 | 3.675 | 0.6149 | 66036.9 | 54600000 | 58200000000 | 74400000000000 | 0.4876 | 0.1751 | 0.0820 | 0.0077 | 0.2182 | 0.0463 | 0.2753 | 0.1683 | 0.1406 | 0.1143 | 0.1083 | 0.1550 | 0.0849 | 0.1907 | 0.0395 | 0.1066 | 0.0249 | 0.0863 | 0.0264 | 0.1248 | 0.0000 | 0.0005 | 0.0009 | 0.0010 | 0.0026 | 0.0022 | 0.0131 | 0.0124 | 0.0707 | 0.0604 | 0.0993 | 0.0897 | 0.0678 | 0.0592 | 0.1013 | 0.0905 | 0.6443 | 0.6841 | 0.0000 | 0.0004 | 0.0004 | 0.0004 | 0.0039 | 0.0019 | 0.0218 | 0.0250 | 0.0761 | 0.0832 | 0.1208 | 0.1271 | 0.0778 | 0.0847 | 0.1127 | 0.1144 | 0.5866 | 0.5630 | 0.0003 | 0.0003 | 0.0029 | 0.0147 | 0.0809 | 0.1055 | 0.0723 | 0.1125 | 0.6106 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 652 | 166 | 1359 | 6119 | 428.9 | 60.31 | 32.37 | 70.62 | 351 | 373 | 390 | 405 | 426 | 446 | 465 | 483 | 508 | 0.0709 | 434 | 0.794 | 97.08 | 19.70 | 1 | 0.1670 | 227 | 0.0023 | 22.07 | 6.272 | 0.2405 | 187585.0 | 83600000 | 38000000000 | 17500000000000 | 0.4204 | 0.2216 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0061 | 0.0000 | 0.0462 | 0.0221 | 0.0688 | 0.0324 | 0.0592 | 0.0191 | 0.0897 | 0.0316 | 0.7265 | 0.8948 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0016 | 0.0000 | 0.0293 | 0.0221 | 0.0443 | 0.0324 | 0.0332 | 0.0191 | 0.0546 | 0.0316 | 0.8347 | 0.8948 | 0.0259 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0776 | 0.0000 | 0.1638 | 0.0000 | 0.1983 | 0.0000 | 0.1207 | 0.0000 | 0.1379 | 0.0000 | 0.2759 | 0.0000 | 0.0000 | 0.0046 | 0.0077 | 0.0107 | 0.0475 | 0.0644 | 0.0706 | 0.0982 | 0.6963 | 6 | 8 | 9 | 10 | 11 | 13 | 15 | 23 | 79 | 0.3514 | 3.58 | 2.313 | 0.8106 | 6034.5 | 2460000 | 1350000000 | 863000000000 | 0.6003 | 0.1052 | 0.0807 | 0.0227 | 0.0807 | 0.0644 | 0.1211 | 0.0814 | 0.2870 | 0.1458 | 0.1435 | 0.1496 | 0.1480 | 0.1458 | 0.0762 | 0.1326 | 0.0583 | 0.1307 | 0.0045 | 0.1269 | 0.0088 | 0.0079 | 0.0044 | 0.0186 | 0.0071 | 0.0193 | 0.0274 | 0.0336 | 0.0398 | 0.0480 | 0.0548 | 0.0523 | 0.0610 | 0.0651 | 0.0839 | 0.0938 | 0.7129 | 0.6614 | 0.0000 | 0.0000 | 0.0044 | 0.0023 | 0.0055 | 0.0046 | 0.0143 | 0.0161 | 0.0539 | 0.0506 | 0.0462 | 0.0598 | 0.0616 | 0.0529 | 0.0935 | 0.0978 | 0.7206 | 0.7158 | 0.0020 | 0.0050 | 0.0090 | 0.0160 | 0.0548 | 0.0439 | 0.0499 | 0.1017 | 0.7178 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1301 | 922 | 1366 | 2845 | 88.3 | 15.42 | 119.74 | 63.45 | 71 | 75 | 79 | 82 | 86 | 89 | 94 | 101 | 110 | 0.1547 | 440 | 0.932 | 89.36 | 30.02 | 1 | 0.1808 | 247 | 0.0068 | 9.05 | 5.271 | 0.3306 | 8028.3 | 753530 | 73100000 | 7320000000 | 0.4490 | 0.1982 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0164 | 0.0023 | 0.0733 | 0.0233 | 0.1485 | 0.0593 | 0.1736 | 0.0360 | 0.2343 | 0.0765 | 0.3481 | 0.8027 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0081 | 0.0022 | 0.0422 | 0.0205 | 0.0755 | 0.0490 | 0.0739 | 0.0190 | 0.1226 | 0.0381 | 0.6761 | 0.8712 | 0.0256 | 0.0303 | 0.0615 | 0.1515 | 0.0308 | 0.1515 | 0.1538 | 0.1212 | 0.1538 | 0.1515 | 0.1590 | 0.2121 | 0.1385 | 0.0909 | 0.1590 | 0.0606 | 0.1179 | 0.0303 | 0.0065 | 0.0114 | 0.0244 | 0.0603 | 0.0945 | 0.1222 | 0.1596 | 0.1417 | 0.3795 | 46 | 63 | 81 | 98 | 113 | 127 | 144 | 167 | 202 | 0.0075 | 7.31 | 5.265 | 0.4258 | 18362.3 | 3410000 | 742000000 | 186000000000 | 0.5900 | 0.1093 | 0.0045 | 0.0032 | 0.0465 | 0.0127 | 0.1213 | 0.0222 | 0.1122 | 0.0565 | 0.1655 | 0.1016 | 0.1565 | 0.1479 | 0.1565 | 0.1384 | 0.1168 | 0.1625 | 0.1202 | 0.3549 | 0.0000 | 0.0019 | 0.0063 | 0.0042 | 0.0091 | 0.0070 | 0.0223 | 0.0164 | 0.0566 | 0.0529 | 0.1189 | 0.0791 | 0.0840 | 0.0669 | 0.1309 | 0.0993 | 0.5720 | 0.6723 | 0.0046 | 0.0107 | 0.0092 | 0.0143 | 0.0288 | 0.0481 | 0.0714 | 0.1016 | 0.1429 | 0.1373 | 0.1705 | 0.1836 | 0.1244 | 0.1390 | 0.1244 | 0.1622 | 0.3237 | 0.2032 | 0.0000 | 0.0101 | 0.0155 | 0.0364 | 0.1006 | 0.1509 | 0.1223 | 0.1409 | 0.4234 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 402 | 136 | 3297 | 12148 | 98.0 | 18.33 | 8.19 | 2.60 | 74 | 80 | 85 | 92 | 97 | 103 | 108 | 114 | 123 | 0.0740 | 899 | 0.685 | 83.76 | 26.42 | 1 | 0.0746 | 246 | 0.0399 | 0.86 | 3.490 | 0.6974 | 9940.2 | 1040000 | 113000000 | 12600000000 | 0.4461 | 0.1984 | 0.0050 | 0.0003 | 0.0077 | 0.0000 | 0.0149 | 0.0019 | 0.0398 | 0.0046 | 0.0430 | 0.0207 | 0.0742 | 0.0377 | 0.0972 | 0.0303 | 0.1470 | 0.0585 | 0.5712 | 0.8460 | 0.0026 | 0.0000 | 0.0018 | 0.0000 | 0.0048 | 0.0015 | 0.0183 | 0.0033 | 0.0202 | 0.0176 | 0.0352 | 0.0303 | 0.0421 | 0.0218 | 0.0546 | 0.0331 | 0.8204 | 0.8923 | 0.0251 | 0.0625 | 0.0309 | 0.0625 | 0.0502 | 0.1719 | 0.0598 | 0.1563 | 0.0927 | 0.1875 | 0.1544 | 0.1406 | 0.1216 | 0.0938 | 0.1564 | 0.0781 | 0.3089 | 0.0469 | 0.0024 | 0.0036 | 0.0134 | 0.0243 | 0.0389 | 0.0584 | 0.0833 | 0.1217 | 0.6539 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0144 | 12.37 | 4.643 | 0.3155 | 73.9 | 721.847 | 7566.38 | 84525.8 | 0.5238 | 0.1413 | 0.0153 | 0.0002 | 0.0771 | 0.0016 | 0.1639 | 0.0070 | 0.2274 | 0.0223 | 0.2309 | 0.0551 | 0.1655 | 0.1102 | 0.0864 | 0.1993 | 0.0283 | 0.3127 | 0.0052 | 0.2916 | 0.0011 | 0.0000 | 0.0072 | 0.0003 | 0.0296 | 0.0015 | 0.0604 | 0.0068 | 0.1020 | 0.0189 | 0.1625 | 0.0400 | 0.2241 | 0.0871 | 0.2509 | 0.2788 | 0.1621 | 0.5666 | 0.0905 | 0.3211 | 0.1651 | 0.2629 | 0.2052 | 0.1761 | 0.1949 | 0.1076 | 0.1565 | 0.0717 | 0.0987 | 0.0351 | 0.0583 | 0.0215 | 0.0222 | 0.0032 | 0.0085 | 0.0008 | 0.0051 | 0.0284 | 0.0735 | 0.1320 | 0.1649 | 0.1938 | 0.1874 | 0.1443 | 0.0706 | |
Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 644 | 300 | 381 | 806 | 12.1 | 3.51 | 5.40 | 1.98 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 17 | 0.3623 | 292 | 0.804 | 32.02 | 8.25 | 0 | 0.2283 | 87 | 0.0100 | 11.54 | 4.797 | 0.2819 | 158.7 | 2234.75 | 33514.1 | 530731 | 0.4187 | 0.2080 | 0.0000 | 0.0000 | 0.0459 | 0.0000 | 0.1429 | 0.0033 | 0.1837 | 0.0262 | 0.2143 | 0.1082 | 0.2245 | 0.1934 | 0.1071 | 0.1836 | 0.0663 | 0.2787 | 0.0153 | 0.2066 | 0.0000 | 0.0000 | 0.0179 | 0.0000 | 0.0286 | 0.0000 | 0.0536 | 0.0143 | 0.0929 | 0.0602 | 0.1071 | 0.0659 | 0.1464 | 0.1347 | 0.1929 | 0.2063 | 0.3607 | 0.5186 | 0.0238 | 0.0682 | 0.1310 | 0.2045 | 0.1310 | 0.1136 | 0.2262 | 0.1591 | 0.1667 | 0.1364 | 0.1548 | 0.2273 | 0.0595 | 0.0455 | 0.0833 | 0.0455 | 0.0238 | 0.0000 | 0.0094 | 0.0330 | 0.0377 | 0.0566 | 0.1226 | 0.1509 | 0.1462 | 0.2217 | 0.2217 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0262 | 8.53 | 4.026 | 0.3635 | 33.1 | 222.937 | 1630.58 | 12844 | 0.5218 | 0.1301 | 0.0340 | 0.0037 | 0.1671 | 0.0201 | 0.2125 | 0.0713 | 0.2351 | 0.1755 | 0.2153 | 0.2194 | 0.0963 | 0.2102 | 0.0397 | 0.1481 | 0.0000 | 0.1097 | 0.0000 | 0.0420 | 0.0014 | 0.0013 | 0.0029 | 0.0000 | 0.0203 | 0.0053 | 0.0695 | 0.0420 | 0.1462 | 0.1183 | 0.1650 | 0.1367 | 0.1838 | 0.1380 | 0.2489 | 0.2076 | 0.1621 | 0.3509 | 0.0355 | 0.1308 | 0.1450 | 0.2664 | 0.2367 | 0.2617 | 0.2426 | 0.1215 | 0.1538 | 0.1308 | 0.0947 | 0.0607 | 0.0562 | 0.0187 | 0.0266 | 0.0000 | 0.0089 | 0.0093 | 0.0018 | 0.0235 | 0.0868 | 0.1374 | 0.1953 | 0.2441 | 0.2080 | 0.0759 | 0.0271 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 441 | 854 | 1964 | 2153 | 94.0 | 19.07 | 5.89 | 2.19 | 65 | 75 | 84 | 91 | 97 | 103 | 107 | 111 | 116 | 0.2216 | 477 | 0.494 | 340.58 | 73.33 | 1 | 0.5046 | 991 | 0.0224 | 1.75 | 4.105 | 0.5669 | 9205.0 | 931383 | 96800000 | 10300000000 | 0.4309 | 0.2010 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0147 | 0.0005 | 0.0359 | 0.0058 | 0.0661 | 0.0242 | 0.1184 | 0.0453 | 0.1380 | 0.0353 | 0.1959 | 0.0679 | 0.4237 | 0.8211 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0013 | 0.0005 | 0.0109 | 0.0052 | 0.0300 | 0.0235 | 0.0504 | 0.0434 | 0.0549 | 0.0314 | 0.0709 | 0.0581 | 0.7797 | 0.8378 | 0.0235 | 0.0909 | 0.0293 | 0.0000 | 0.0704 | 0.1818 | 0.1056 | 0.0909 | 0.1144 | 0.3636 | 0.1525 | 0.2727 | 0.1290 | 0.0000 | 0.1290 | 0.0000 | 0.2463 | 0.0000 | 0.0000 | 0.0027 | 0.0045 | 0.0163 | 0.0506 | 0.0624 | 0.0678 | 0.0850 | 0.7107 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5417 | 0.29 | 0.926 | 0.8524 | 39.5 | 290.243 | 2305.17 | 19573.6 | 0.5333 | 0.1268 | 0.0126 | 0.0006 | 0.0816 | 0.0054 | 0.1641 | 0.0320 | 0.2592 | 0.0633 | 0.2505 | 0.1333 | 0.1534 | 0.1960 | 0.0621 | 0.2340 | 0.0155 | 0.2117 | 0.0010 | 0.1236 | 0.0000 | 0.0000 | 0.0139 | 0.0011 | 0.0357 | 0.0096 | 0.1130 | 0.0340 | 0.1897 | 0.0919 | 0.2161 | 0.1338 | 0.2254 | 0.1875 | 0.1586 | 0.2953 | 0.0476 | 0.2469 | 0.1946 | 0.4222 | 0.2754 | 0.2667 | 0.2402 | 0.1378 | 0.1718 | 0.1244 | 0.0787 | 0.0400 | 0.0311 | 0.0089 | 0.0062 | 0.0000 | 0.0021 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0552 | 0.1027 | 0.1986 | 0.2182 | 0.1910 | 0.1171 | 0.0849 | 0.0246 | |
SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1207 | 207 | 6980 | 19624 | 335.7 | 74.32 | 299.24 | 411.18 | 218 | 282 | 315 | 337 | 355 | 370 | 382 | 395 | 412 | 0.0495 | 972 | 0.878 | 105.01 | 22.67 | 2 | 0.0338 | 236 | 0.0016 | 18.87 | 6.802 | 0.2595 | 118201.0 | 43000000 | 16000000000 | 6030000000000 | 0.3992 | 0.2312 | 0.0008 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0000 | 0.0151 | 0.0005 | 0.0362 | 0.0109 | 0.0496 | 0.0198 | 0.0603 | 0.0114 | 0.1042 | 0.0181 | 0.7262 | 0.9392 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0005 | 0.0117 | 0.0106 | 0.0200 | 0.0197 | 0.0164 | 0.0105 | 0.0219 | 0.0154 | 0.9264 | 0.9434 | 0.0234 | 0.1429 | 0.0263 | 0.0000 | 0.0536 | 0.4286 | 0.0623 | 0.2857 | 0.0837 | 0.1429 | 0.1003 | 0.0000 | 0.1120 | 0.0000 | 0.1324 | 0.0000 | 0.4060 | 0.0000 | 0.0007 | 0.0016 | 0.0028 | 0.0094 | 0.0211 | 0.0392 | 0.0446 | 0.0634 | 0.8170 | 12 | 16 | 20 | 28 | 78 | 180 | 350 | 599 | 943 | 0.0721 | 64.70 | 5.520 | 0.4930 | 258610.0 | 294000000 | 385000000000 | 559000000000000 | 0.4020 | 0.2305 | 0.0543 | 0.0023 | 0.2124 | 0.0098 | 0.3077 | 0.0976 | 0.1647 | 0.1574 | 0.1179 | 0.2237 | 0.0828 | 0.2003 | 0.0326 | 0.1140 | 0.0217 | 0.0910 | 0.0059 | 0.1039 | 0.0003 | 0.0000 | 0.0001 | 0.0001 | 0.0013 | 0.0004 | 0.0073 | 0.0059 | 0.0473 | 0.0415 | 0.0872 | 0.0708 | 0.0574 | 0.0514 | 0.0844 | 0.0737 | 0.7147 | 0.7561 | 0.0003 | 0.0002 | 0.0014 | 0.0008 | 0.0026 | 0.0025 | 0.0115 | 0.0140 | 0.0574 | 0.0661 | 0.1058 | 0.1190 | 0.0739 | 0.0814 | 0.1015 | 0.1092 | 0.6456 | 0.6068 | 0.0002 | 0.0005 | 0.0011 | 0.0070 | 0.0580 | 0.0920 | 0.0640 | 0.0926 | 0.6846 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 580 | 433 | 1493 | 7000 | 280.3 | 39.92 | 26.94 | 45.70 | 230 | 246 | 259 | 269 | 278 | 289 | 298 | 312 | 333 | 0.0730 | 511 | 0.722 | 72.57 | 16.03 | 1 | 0.1092 | 163 | 0.0044 | 8.62 | 5.687 | 0.3499 | 80150.8 | 23400000 | 6950000000 | 2110000000000 | 0.4223 | 0.2148 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0007 | 0.0385 | 0.0235 | 0.0577 | 0.0450 | 0.0513 | 0.0215 | 0.0810 | 0.0403 | 0.7642 | 0.8690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0007 | 0.0246 | 0.0221 | 0.0377 | 0.0442 | 0.0261 | 0.0181 | 0.0399 | 0.0328 | 0.8681 | 0.8821 | 0.0226 | 0.2000 | 0.0150 | 0.2000 | 0.0526 | 0.4000 | 0.0677 | 0.2000 | 0.0602 | 0.0000 | 0.1053 | 0.0000 | 0.0902 | 0.0000 | 0.1278 | 0.0000 | 0.4586 | 0.0000 | 0.0014 | 0.0014 | 0.0069 | 0.0220 | 0.0495 | 0.0755 | 0.0975 | 0.1319 | 0.6140 | 7 | 8 | 9 | 10 | 12 | 15 | 20 | 33 | 57 | 0.2933 | 1.67 | 2.358 | 0.8342 | 2814.2 | 777978 | 343000000 | 188000000000 | 0.6091 | 0.1098 | 0.0437 | 0.0353 | 0.0542 | 0.0453 | 0.0822 | 0.0637 | 0.1014 | 0.0599 | 0.1294 | 0.0860 | 0.1451 | 0.1083 | 0.1521 | 0.1045 | 0.1573 | 0.1421 | 0.1346 | 0.3548 | 0.0065 | 0.0172 | 0.0101 | 0.0192 | 0.0081 | 0.0204 | 0.0141 | 0.0188 | 0.0252 | 0.0337 | 0.0348 | 0.0425 | 0.0403 | 0.0357 | 0.0685 | 0.0665 | 0.7924 | 0.7459 | 0.0035 | 0.0050 | 0.0042 | 0.0084 | 0.0099 | 0.0168 | 0.0156 | 0.0218 | 0.0453 | 0.0536 | 0.0545 | 0.0662 | 0.0630 | 0.0679 | 0.1288 | 0.1274 | 0.6752 | 0.6329 | 0.0024 | 0.0047 | 0.0082 | 0.0141 | 0.0294 | 0.0500 | 0.0488 | 0.1106 | 0.7318 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1240 | 782 | 5520 | 5479 | 133.2 | 23.75 | 110.66 | 100.88 | 104 | 113 | 119 | 126 | 132 | 138 | 144 | 152 | 163 | 0.1374 | 753 | 0.999 | 91.29 | 24.70 | 1 | 0.0397 | 219 | 0.0031 | 14.38 | 6.066 | 0.2851 | 18294.8 | 2590000 | 379000000 | 57200000000 | 0.4125 | 0.2388 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0002 | 0.0212 | 0.0007 | 0.0442 | 0.0156 | 0.0934 | 0.0282 | 0.1204 | 0.0252 | 0.1646 | 0.0404 | 0.5507 | 0.8897 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0083 | 0.0002 | 0.0228 | 0.0129 | 0.0452 | 0.0203 | 0.0504 | 0.0132 | 0.0765 | 0.0234 | 0.7949 | 0.9300 | 0.0226 | 0.0169 | 0.0155 | 0.0763 | 0.0523 | 0.1102 | 0.1088 | 0.1102 | 0.1638 | 0.1525 | 0.1723 | 0.2034 | 0.1201 | 0.1356 | 0.1554 | 0.0847 | 0.1893 | 0.1102 | 0.0033 | 0.0089 | 0.0118 | 0.0380 | 0.0687 | 0.1048 | 0.1063 | 0.1384 | 0.5197 | 27 | 36 | 47 | 60 | 75 | 95 | 123 | 168 | 249 | 0.0062 | 29.53 | 5.971 | 0.3642 | 22419.6 | 6640000 | 2430000000 | 1010000000000 | 0.6287 | 0.0903 | 0.0259 | 0.0043 | 0.1147 | 0.0103 | 0.2160 | 0.0511 | 0.1732 | 0.0983 | 0.1395 | 0.1836 | 0.1192 | 0.1825 | 0.0934 | 0.1477 | 0.0742 | 0.1266 | 0.0439 | 0.1955 | 0.0017 | 0.0020 | 0.0034 | 0.0039 | 0.0089 | 0.0098 | 0.0326 | 0.0219 | 0.0852 | 0.0732 | 0.1360 | 0.1023 | 0.1004 | 0.0859 | 0.1513 | 0.1366 | 0.4805 | 0.5644 | 0.0020 | 0.0025 | 0.0095 | 0.0033 | 0.0102 | 0.0172 | 0.0428 | 0.0582 | 0.1292 | 0.1534 | 0.1747 | 0.1838 | 0.1237 | 0.1017 | 0.1475 | 0.1403 | 0.3603 | 0.3396 | 0.0016 | 0.0064 | 0.0155 | 0.0321 | 0.1095 | 0.1474 | 0.1239 | 0.1394 | 0.4241 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 343 | 266 | 9188 | 10970 | 380.5 | 50.11 | 368.80 | 331.03 | 317 | 338 | 353 | 366 | 379 | 392 | 407 | 423 | 446 | 0.0837 | 918 | 1.098 | 128.97 | 29.02 | 1 | 0.0293 | 269 | 0.0014 | 32.93 | 6.904 | 0.2140 | 147263.0 | 58000000 | 23200000000 | 9410000000000 | 0.4808 | 0.1754 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0047 | 0.0002 | 0.0250 | 0.0095 | 0.0514 | 0.0210 | 0.0529 | 0.0104 | 0.0987 | 0.0165 | 0.7665 | 0.9424 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0001 | 0.0138 | 0.0095 | 0.0278 | 0.0207 | 0.0261 | 0.0093 | 0.0415 | 0.0143 | 0.8895 | 0.9462 | 0.0218 | 0.0000 | 0.0328 | 0.0000 | 0.0593 | 0.0000 | 0.0874 | 0.0000 | 0.1732 | 0.0000 | 0.1841 | 0.0000 | 0.1435 | 0.0000 | 0.1388 | 0.0000 | 0.1591 | 0.0000 | 0.0011 | 0.0040 | 0.0097 | 0.0303 | 0.0725 | 0.1067 | 0.1129 | 0.1309 | 0.5320 | 26 | 44 | 103 | 182 | 274 | 391 | 529 | 679 | 850 | 0.0115 | 87.23 | 6.899 | 0.3039 | 245585.0 | 203000000 | 190000000000 | 195000000000000 | 0.5450 | 0.1332 | 0.0240 | 0.0019 | 0.1159 | 0.0052 | 0.2589 | 0.0480 | 0.1785 | 0.1152 | 0.1414 | 0.1989 | 0.1291 | 0.2063 | 0.0765 | 0.1279 | 0.0433 | 0.1290 | 0.0325 | 0.1677 | 0.0004 | 0.0003 | 0.0015 | 0.0005 | 0.0044 | 0.0031 | 0.0158 | 0.0085 | 0.0472 | 0.0440 | 0.0846 | 0.0769 | 0.0584 | 0.0516 | 0.0824 | 0.0766 | 0.7053 | 0.7384 | 0.0003 | 0.0009 | 0.0025 | 0.0032 | 0.0058 | 0.0059 | 0.0156 | 0.0215 | 0.0666 | 0.0792 | 0.1115 | 0.1340 | 0.0860 | 0.1022 | 0.1267 | 0.1240 | 0.5849 | 0.5290 | 0.0000 | 0.0026 | 0.0050 | 0.0109 | 0.0579 | 0.0934 | 0.0690 | 0.0986 | 0.6626 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 182 | 324 | 4862 | 8847 | 382.1 | 46.56 | 84.31 | 223.89 | 321 | 348 | 363 | 376 | 385 | 395 | 406 | 419 | 440 | 0.0849 | 751 | 0.869 | 141.40 | 42.45 | 2 | 0.0755 | 367 | 0.0020 | 27.89 | 6.580 | 0.2423 | 148135.0 | 58200000 | 23200000000 | 9310000000000 | 0.4327 | 0.2087 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0000 | 0.0215 | 0.0134 | 0.0430 | 0.0245 | 0.0423 | 0.0117 | 0.0642 | 0.0210 | 0.8233 | 0.9294 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0153 | 0.0134 | 0.0306 | 0.0245 | 0.0237 | 0.0117 | 0.0317 | 0.0210 | 0.8966 | 0.9294 | 0.0214 | 0.0000 | 0.0856 | 0.0000 | 0.1016 | 0.0000 | 0.1283 | 0.0000 | 0.1176 | 0.0000 | 0.1444 | 0.0000 | 0.1016 | 0.0000 | 0.1123 | 0.0000 | 0.1872 | 0.0000 | 0.0019 | 0.0049 | 0.0106 | 0.0314 | 0.0538 | 0.0947 | 0.0981 | 0.1163 | 0.5883 | 8 | 9 | 11 | 12 | 13 | 15 | 20 | 43 | 199 | 0.1434 | 6.44 | 2.531 | 0.5616 | 57228.9 | 60400000 | 73600000000 | 96900000000000 | 0.7057 | 0.0462 | 0.0466 | 0.0000 | 0.0975 | 0.0157 | 0.2458 | 0.0747 | 0.1144 | 0.1041 | 0.1653 | 0.1434 | 0.1483 | 0.1945 | 0.1102 | 0.1611 | 0.0466 | 0.1336 | 0.0254 | 0.1729 | 0.0007 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0048 | 0.0144 | 0.0133 | 0.0390 | 0.0387 | 0.0787 | 0.0678 | 0.0568 | 0.0599 | 0.1026 | 0.0998 | 0.7066 | 0.7145 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0016 | 0.0009 | 0.0122 | 0.0192 | 0.0636 | 0.0603 | 0.0865 | 0.0857 | 0.0530 | 0.0594 | 0.1117 | 0.0970 | 0.6713 | 0.6740 | 0.0000 | 0.0008 | 0.0023 | 0.0129 | 0.0530 | 0.0802 | 0.0560 | 0.1104 | 0.6846 |