High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1130 | 267 | | 5490 | 23038 | 164.0 | 66.56 | 28.31 | 61.33 | 83 | 103 | 121 | 140 | 156 | 173 | 190 | 215 | 271 | 0.0512 | 1180 | 0.983 | 61.59 | 20.03 | 5 | 0.0288 | 158 | 0.0023 | 6.37 | 6.316 | 0.3881 | 31316.4 | 6760000 | 1600000000 | 408000000000 | 0.3733 | 0.2534 | 0.0000 | 0.0000 | 0.0019 | 0.0025 | 0.0077 | 0.0028 | 0.0178 | 0.0083 | 0.0548 | 0.0230 | 0.0836 | 0.0418 | 0.1000 | 0.0452 | 0.1629 | 0.0593 | 0.5714 | 0.8171 | 0.0000 | 0.0000 | 0.0011 | 0.0015 | 0.0023 | 0.0018 | 0.0056 | 0.0051 | 0.0158 | 0.0124 | 0.0237 | 0.0218 | 0.0259 | 0.0218 | 0.0440 | 0.0294 | 0.8816 | 0.9062 | 0.0027 | 0.0011 | 0.0075 | 0.0054 | 0.0137 | 0.0087 | 0.0239 | 0.0130 | 0.0321 | 0.0369 | 0.0498 | 0.0510 | 0.0546 | 0.0304 | 0.0539 | 0.0542 | 0.7618 | 0.7993 | 0.0000 | 0.0012 | 0.0056 | 0.0164 | 0.0308 | 0.0504 | 0.0496 | 0.0712 | 0.7747 | 7 | 9 | 10 | 12 | 13 | 15 | 18 | 25 | 46 | 0.1947 | 4.25 | 2.622 | 0.7761 | 4562.8 | 1730000 | 803000000 | 408000000000 | 0.5689 | 0.1210 | 0.0523 | 0.0587 | 0.0562 | 0.0581 | 0.0812 | 0.0637 | 0.1251 | 0.0665 | 0.1413 | 0.0729 | 0.1613 | 0.0863 | 0.1935 | 0.0999 | 0.1268 | 0.1500 | 0.0623 | 0.3441 | 0.0140 | 0.0361 | 0.0138 | 0.0353 | 0.0177 | 0.0353 | 0.0272 | 0.0346 | 0.0400 | 0.0414 | 0.0560 | 0.0533 | 0.0641 | 0.0585 | 0.0971 | 0.0880 | 0.6701 | 0.6175 | 0.0057 | 0.0047 | 0.0093 | 0.0061 | 0.0131 | 0.0140 | 0.0191 | 0.0201 | 0.0508 | 0.0635 | 0.0669 | 0.0793 | 0.0770 | 0.0840 | 0.1123 | 0.1231 | 0.6459 | 0.6053 | 0.0104 | 0.0106 | 0.0164 | 0.0205 | 0.0425 | 0.0614 | 0.0594 | 0.1068 | 0.6718 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1162 | 503 | | 2529 | 2344 | 126.3 | 43.34 | 188.90 | 122.03 | 73 | 88 | 100 | 110 | 122 | 133 | 145 | 162 | 185 | 0.1950 | 457 | 0.720 | 84.38 | 20.03 | 1 | 0.0834 | 211 | 0.0009 | 89.32 | 7.225 | 0.1409 | 17828.9 | 2770000 | 469000000 | 85100000000 | 0.4531 | 0.1879 | 0.0000 | 0.0000 | 0.0045 | 0.0021 | 0.0334 | 0.0032 | 0.0885 | 0.0117 | 0.1554 | 0.0573 | 0.2069 | 0.1183 | 0.1527 | 0.1210 | 0.1509 | 0.1666 | 0.2078 | 0.5199 | 0.0000 | 0.0000 | 0.0006 | 0.0013 | 0.0023 | 0.0018 | 0.0153 | 0.0081 | 0.0512 | 0.0346 | 0.0904 | 0.0606 | 0.0745 | 0.0454 | 0.0944 | 0.0718 | 0.6714 | 0.7764 | 0.0031 | 0.0088 | 0.0077 | 0.0263 | 0.0153 | 0.0351 | 0.0537 | 0.0906 | 0.1503 | 0.1579 | 0.1656 | 0.1813 | 0.1012 | 0.0906 | 0.1518 | 0.1579 | 0.3512 | 0.2515 | 0.0000 | 0.0009 | 0.0043 | 0.0282 | 0.1059 | 0.1443 | 0.1059 | 0.1460 | 0.4646 | 57 | 75 | 104 | 135 | 169 | 201 | 239 | 281 | 355 | 0.0049 | 19.35 | 5.900 | 0.3617 | 50569.7 | 17000000 | 6670000000 | 2960000000000 | 0.5121 | 0.1476 | 0.0119 | 0.0010 | 0.0889 | 0.0089 | 0.1976 | 0.0207 | 0.1621 | 0.0720 | 0.1581 | 0.1519 | 0.1561 | 0.2002 | 0.0870 | 0.1322 | 0.0870 | 0.1686 | 0.0514 | 0.2446 | 0.0000 | 0.0006 | 0.0008 | 0.0006 | 0.0093 | 0.0025 | 0.0202 | 0.0153 | 0.0644 | 0.0567 | 0.1149 | 0.0943 | 0.0901 | 0.0732 | 0.1335 | 0.1115 | 0.5668 | 0.6452 | 0.0013 | 0.0090 | 0.0064 | 0.0162 | 0.0153 | 0.0252 | 0.0435 | 0.0629 | 0.1228 | 0.1457 | 0.1662 | 0.1853 | 0.1368 | 0.1097 | 0.1675 | 0.1583 | 0.3402 | 0.2878 | 0.0000 | 0.0019 | 0.0135 | 0.0348 | 0.0890 | 0.1277 | 0.1180 | 0.1750 | 0.4400 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1142 | 857 | | 7401 | 14616 | 171.0 | 66.26 | 71.29 | 133.72 | 97 | 113 | 126 | 141 | 159 | 177 | 198 | 227 | 267 | 0.0757 | 1106 | 0.455 | 200.25 | 41.00 | 7 | 0.0947 | 701 | 0.0014 | 22.02 | 6.984 | 0.2885 | 33621.9 | 7480000 | 1840000000 | 492000000000 | 0.3427 | 0.2805 | 0.0023 | 0.0008 | 0.0023 | 0.0025 | 0.0164 | 0.0059 | 0.0279 | 0.0086 | 0.0707 | 0.0301 | 0.1250 | 0.0604 | 0.1170 | 0.0539 | 0.1514 | 0.0722 | 0.4868 | 0.7658 | 0.0004 | 0.0005 | 0.0013 | 0.0012 | 0.0054 | 0.0022 | 0.0073 | 0.0043 | 0.0207 | 0.0130 | 0.0326 | 0.0254 | 0.0318 | 0.0221 | 0.0443 | 0.0300 | 0.8561 | 0.9014 | 0.0010 | 0.0000 | 0.0030 | 0.0041 | 0.0094 | 0.0058 | 0.0189 | 0.0386 | 0.0506 | 0.0641 | 0.0839 | 0.1191 | 0.0645 | 0.0994 | 0.0948 | 0.1224 | 0.6738 | 0.5464 | 0.0012 | 0.0025 | 0.0065 | 0.0109 | 0.0349 | 0.0477 | 0.0514 | 0.0767 | 0.7681 | 10 | 12 | 14 | 16 | 20 | 33 | 59 | 100 | 185 | 0.1556 | 7.37 | 3.609 | 0.6941 | 22963.2 | 18300000 | 21700000000 | 29800000000000 | 0.5623 | 0.1121 | 0.0192 | 0.0013 | 0.1028 | 0.0217 | 0.1742 | 0.0579 | 0.2030 | 0.0744 | 0.1838 | 0.1431 | 0.1324 | 0.1783 | 0.0941 | 0.1601 | 0.0662 | 0.1353 | 0.0244 | 0.2279 | 0.0000 | 0.0002 | 0.0020 | 0.0025 | 0.0051 | 0.0046 | 0.0151 | 0.0122 | 0.0523 | 0.0408 | 0.0785 | 0.0615 | 0.0621 | 0.0522 | 0.0923 | 0.0762 | 0.6926 | 0.7500 | 0.0006 | 0.0003 | 0.0012 | 0.0037 | 0.0062 | 0.0075 | 0.0211 | 0.0251 | 0.0699 | 0.0728 | 0.1077 | 0.1162 | 0.0759 | 0.0799 | 0.1107 | 0.1118 | 0.6067 | 0.5827 | 0.0003 | 0.0008 | 0.0031 | 0.0230 | 0.0637 | 0.0872 | 0.0730 | 0.0993 | 0.6497 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 563 | 523 | | 7584 | 13597 | 292.9 | 83.06 | 182.75 | 174.84 | 193 | 209 | 226 | 248 | 286 | 322 | 349 | 375 | 408 | 0.0785 | 1067 | 1.101 | 127.77 | 42.45 | 1 | 0.0407 | 309 | 0.0016 | 18.42 | 6.833 | 0.3003 | 92706.4 | 31400000 | 11200000000 | 4180000000000 | 0.4037 | 0.2427 | 0.0029 | 0.0000 | 0.0068 | 0.0012 | 0.0184 | 0.0023 | 0.0417 | 0.0059 | 0.0763 | 0.0230 | 0.1000 | 0.0516 | 0.1051 | 0.0428 | 0.1263 | 0.0614 | 0.5225 | 0.8120 | 0.0010 | 0.0000 | 0.0022 | 0.0011 | 0.0026 | 0.0007 | 0.0070 | 0.0022 | 0.0191 | 0.0112 | 0.0291 | 0.0256 | 0.0275 | 0.0134 | 0.0388 | 0.0299 | 0.8726 | 0.9160 | 0.0014 | 0.0000 | 0.0023 | 0.0000 | 0.0073 | 0.0000 | 0.0200 | 0.0000 | 0.0514 | 0.0000 | 0.0906 | 0.0000 | 0.0915 | 0.0000 | 0.1138 | 0.0000 | 0.6218 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0055 | 0.0191 | 0.0372 | 0.0372 | 0.0563 | 0.8437 | 21 | 37 | 61 | 91 | 127 | 171 | 226 | 307 | 431 | 0.0098 | 23.73 | 6.012 | 0.4274 | 63963.5 | 31000000 | 18200000000 | 12200000000000 | 0.4970 | 0.1734 | 0.0146 | 0.0008 | 0.0690 | 0.0059 | 0.1458 | 0.0403 | 0.1437 | 0.0687 | 0.1813 | 0.1390 | 0.1557 | 0.1647 | 0.0967 | 0.1352 | 0.0810 | 0.1280 | 0.1123 | 0.3175 | 0.0002 | 0.0000 | 0.0006 | 0.0014 | 0.0034 | 0.0032 | 0.0156 | 0.0128 | 0.0523 | 0.0433 | 0.0827 | 0.0651 | 0.0658 | 0.0553 | 0.0969 | 0.0768 | 0.6825 | 0.7421 | 0.0007 | 0.0011 | 0.0009 | 0.0049 | 0.0082 | 0.0066 | 0.0238 | 0.0255 | 0.0714 | 0.0887 | 0.1100 | 0.1319 | 0.0872 | 0.0887 | 0.1249 | 0.1379 | 0.5728 | 0.5147 | 0.0002 | 0.0029 | 0.0057 | 0.0176 | 0.0629 | 0.0975 | 0.0805 | 0.1129 | 0.6198 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 770 | 194 | | 4106 | 14842 | 217.4 | 110.14 | 102.63 | 168.85 | 87 | 104 | 124 | 149 | 193 | 255 | 309 | 338 | 368 | 0.0595 | 883 | 0.734 | 130.10 | 25.02 | 4 | 0.0774 | 318 | 0.0016 | 20.13 | 6.862 | 0.2708 | 59394.7 | 18600000 | 6250000000 | 2190000000000 | 0.3003 | 0.3143 | 0.0017 | 0.0020 | 0.0017 | 0.0047 | 0.0050 | 0.0027 | 0.0199 | 0.0182 | 0.1393 | 0.0532 | 0.2703 | 0.1097 | 0.1294 | 0.0787 | 0.1592 | 0.1016 | 0.2736 | 0.6292 | 0.0000 | 0.0004 | 0.0000 | 0.0011 | 0.0005 | 0.0007 | 0.0014 | 0.0043 | 0.0199 | 0.0180 | 0.0398 | 0.0371 | 0.0172 | 0.0213 | 0.0330 | 0.0317 | 0.8883 | 0.8853 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0019 | 0.0023 | 0.0025 | 0.0070 | 0.0243 | 0.0319 | 0.0473 | 0.0474 | 0.0230 | 0.0365 | 0.0398 | 0.0629 | 0.8613 | 0.8096 | 0.0000 | 0.0000 | 0.0010 | 0.0047 | 0.0210 | 0.0367 | 0.0257 | 0.0352 | 0.8756 | 12 | 15 | 18 | 23 | 35 | 53 | 82 | 137 | 279 | 0.0621 | 16.73 | 4.450 | 0.6158 | 39039.8 | 25800000 | 21500000000 | 20400000000000 | 0.5806 | 0.1178 | 0.0142 | 0.0012 | 0.0745 | 0.0050 | 0.1347 | 0.0255 | 0.1665 | 0.0751 | 0.1808 | 0.1211 | 0.1548 | 0.1645 | 0.1163 | 0.1413 | 0.0879 | 0.1463 | 0.0703 | 0.3200 | 0.0004 | 0.0002 | 0.0022 | 0.0006 | 0.0034 | 0.0017 | 0.0117 | 0.0140 | 0.0549 | 0.0436 | 0.0904 | 0.0624 | 0.0616 | 0.0618 | 0.0940 | 0.0822 | 0.6814 | 0.7336 | 0.0000 | 0.0000 | 0.0015 | 0.0028 | 0.0065 | 0.0070 | 0.0175 | 0.0228 | 0.0713 | 0.0831 | 0.1208 | 0.1189 | 0.0799 | 0.0856 | 0.1097 | 0.1140 | 0.5927 | 0.5658 | 0.0008 | 0.0024 | 0.0040 | 0.0129 | 0.0630 | 0.1018 | 0.0691 | 0.1036 | 0.6424 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 273 | 873 | | 959 | 20054 | 113.6 | 15.41 | 28.35 | 38.32 | 95 | 99 | 103 | 107 | 113 | 117 | 121 | 127 | 135 | 0.0524 | 1050 | 1.034 | 39.40 | 13.04 | 0 | 0.1064 | 102 | 0.0763 | 0.50 | 2.832 | 0.7708 | 13136.1 | 1550000 | 186000000 | 22800000000 | 0.4056 | 0.2400 | 0.0012 | 0.0000 | 0.0036 | 0.0010 | 0.0083 | 0.0031 | 0.0154 | 0.0073 | 0.0473 | 0.0241 | 0.0746 | 0.0640 | 0.0734 | 0.0325 | 0.1006 | 0.0598 | 0.6757 | 0.8080 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0076 | 0.0031 | 0.0108 | 0.0073 | 0.0314 | 0.0229 | 0.0541 | 0.0615 | 0.0400 | 0.0250 | 0.0639 | 0.0532 | 0.7879 | 0.8259 | 0.0000 | 0.0000 | 0.0127 | 0.1667 | 0.0506 | 0.0000 | 0.1013 | 0.5000 | 0.1266 | 0.3333 | 0.1392 | 0.0000 | 0.1266 | 0.0000 | 0.1266 | 0.0000 | 0.3165 | 0.0000 | 0.0022 | 0.0043 | 0.0152 | 0.0260 | 0.0390 | 0.0758 | 0.0736 | 0.1017 | 0.6623 | 11 | 13 | 15 | 17 | 20 | 22 | 26 | 31 | 40 | 0.3245 | 0.91 | 1.880 | 0.8551 | 2272.4 | 507754 | 174000000 | 71000000000 | 0.5696 | 0.1296 | 0.0433 | 0.0176 | 0.0600 | 0.0218 | 0.0785 | 0.0264 | 0.1039 | 0.0386 | 0.1265 | 0.0642 | 0.1678 | 0.0809 | 0.1887 | 0.1079 | 0.1421 | 0.1846 | 0.0893 | 0.4581 | 0.0240 | 0.0144 | 0.0282 | 0.0178 | 0.0330 | 0.0204 | 0.0353 | 0.0280 | 0.0502 | 0.0467 | 0.0618 | 0.0603 | 0.0746 | 0.0721 | 0.1061 | 0.1150 | 0.5867 | 0.6253 | 0.0284 | 0.0348 | 0.0315 | 0.0221 | 0.0495 | 0.0172 | 0.0486 | 0.0255 | 0.0769 | 0.0594 | 0.0874 | 0.0790 | 0.0867 | 0.0795 | 0.1126 | 0.1286 | 0.4784 | 0.5540 | 0.0222 | 0.0261 | 0.0286 | 0.0380 | 0.0551 | 0.0752 | 0.0968 | 0.1505 | 0.5076 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 382 | 482 | | 6733 | 6438 | 43.2 | 12.21 | 112.41 | 165.59 | 28 | 32 | 35 | 39 | 42 | 46 | 50 | 54 | 60 | 0.1785 | 1149 | 1.039 | 54.34 | 16.16 | 3 | 0.0192 | 129 | 0.0360 | 0.84 | 3.592 | 0.6983 | 2014.6 | 100311 | 5270000 | 290000000 | 0.3887 | 0.2344 | 0.0060 | 0.0014 | 0.0139 | 0.0039 | 0.0220 | 0.0043 | 0.0460 | 0.0107 | 0.0794 | 0.0318 | 0.1389 | 0.0469 | 0.1480 | 0.0529 | 0.1880 | 0.0959 | 0.3578 | 0.7522 | 0.0027 | 0.0005 | 0.0041 | 0.0010 | 0.0078 | 0.0010 | 0.0188 | 0.0052 | 0.0347 | 0.0229 | 0.0580 | 0.0316 | 0.0586 | 0.0321 | 0.0858 | 0.0495 | 0.7295 | 0.8563 | 0.0070 | 0.0313 | 0.0186 | 0.0224 | 0.0256 | 0.0328 | 0.0413 | 0.0627 | 0.0721 | 0.0687 | 0.0809 | 0.1224 | 0.0878 | 0.1328 | 0.1268 | 0.1597 | 0.5398 | 0.3672 | 0.0033 | 0.0090 | 0.0189 | 0.0269 | 0.0452 | 0.0619 | 0.0736 | 0.0984 | 0.6628 | 7 | 8 | 10 | 12 | 19 | 48 | 124 | 221 | 345 | 0.0718 | 6.66 | 3.779 | 0.5031 | 40050.5 | 19600000 | 11300000000 | 7260000000000 | 0.4549 | 0.1859 | 0.0359 | 0.0046 | 0.1257 | 0.0170 | 0.2036 | 0.0880 | 0.1916 | 0.1173 | 0.1796 | 0.1867 | 0.1168 | 0.1929 | 0.0778 | 0.1312 | 0.0539 | 0.1281 | 0.0150 | 0.1343 | 0.0005 | 0.0008 | 0.0014 | 0.0021 | 0.0023 | 0.0008 | 0.0087 | 0.0068 | 0.0407 | 0.0343 | 0.0535 | 0.0525 | 0.0512 | 0.0423 | 0.0699 | 0.0728 | 0.7719 | 0.7875 | 0.0005 | 0.0000 | 0.0000 | 0.0012 | 0.0022 | 0.0041 | 0.0097 | 0.0146 | 0.0529 | 0.0578 | 0.0707 | 0.0776 | 0.0723 | 0.0712 | 0.0960 | 0.0968 | 0.6958 | 0.6768 | 0.0000 | 0.0010 | 0.0035 | 0.0144 | 0.0416 | 0.0575 | 0.0615 | 0.0878 | 0.7328 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 477 | 785 | | 2057 | 7126 | 15.8 | 5.35 | 5.58 | 1.94 | 10 | 11 | 13 | 14 | 15 | 16 | 18 | 20 | 22 | 0.1343 | 957 | 1.077 | 39.62 | 14.00 | 0 | 0.0501 | 103 | 0.0083 | 6.76 | 5.098 | 0.3940 | 278.8 | 5536.95 | 125712 | 3300000 | 0.3803 | 0.2578 | 0.0068 | 0.0000 | 0.0241 | 0.0017 | 0.0395 | 0.0081 | 0.0656 | 0.0237 | 0.1070 | 0.0317 | 0.1466 | 0.0531 | 0.1688 | 0.1073 | 0.2054 | 0.1604 | 0.2363 | 0.6140 | 0.0048 | 0.0000 | 0.0131 | 0.0010 | 0.0220 | 0.0068 | 0.0275 | 0.0167 | 0.0440 | 0.0256 | 0.0557 | 0.0329 | 0.0688 | 0.0605 | 0.0922 | 0.0924 | 0.6717 | 0.7641 | 0.0168 | 0.0437 | 0.0216 | 0.0437 | 0.0481 | 0.0328 | 0.0793 | 0.0656 | 0.0865 | 0.1038 | 0.1346 | 0.1093 | 0.1298 | 0.0710 | 0.1394 | 0.1749 | 0.3438 | 0.3552 | 0.0178 | 0.0231 | 0.0241 | 0.0409 | 0.0409 | 0.0682 | 0.0860 | 0.1091 | 0.5897 | 3 | 4 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0254 | 8.33 | 4.093 | 0.3635 | 34.9 | 237.89 | 1743 | 13611.8 | 0.5441 | 0.1416 | 0.0029 | 0.0002 | 0.0262 | 0.0017 | 0.0867 | 0.0113 | 0.1633 | 0.0354 | 0.2318 | 0.0789 | 0.2315 | 0.1447 | 0.1584 | 0.2575 | 0.0821 | 0.2968 | 0.0170 | 0.1734 | 0.0004 | 0.0002 | 0.0045 | 0.0006 | 0.0189 | 0.0043 | 0.0680 | 0.0220 | 0.1231 | 0.0509 | 0.2194 | 0.0876 | 0.2719 | 0.1709 | 0.2172 | 0.3403 | 0.0767 | 0.3232 | 0.2384 | 0.4990 | 0.3216 | 0.3638 | 0.2659 | 0.1113 | 0.1235 | 0.0258 | 0.0369 | 0.0000 | 0.0129 | 0.0000 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0115 | 0.0662 | 0.1649 | 0.2477 | 0.2359 | 0.1587 | 0.0825 | 0.0266 | 0.0059 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 481 | 100 | | 7950 | 9207 | 278.6 | 129.42 | 10.26 | 12.06 | 144 | 163 | 187 | 215 | 241 | 273 | 314 | 413 | 495 | 0.0924 | 851 | 0.695 | 94.53 | 15.03 | 6 | 0.0267 | 212 | 0.0018 | 9.35 | 6.724 | 0.3596 | 94338.5 | 37400000 | 16500000000 | 7810000000000 | 0.4212 | 0.2162 | 0.0009 | 0.0016 | 0.0013 | 0.0016 | 0.0068 | 0.0043 | 0.0175 | 0.0086 | 0.0554 | 0.0374 | 0.0967 | 0.0491 | 0.0797 | 0.0423 | 0.1121 | 0.0623 | 0.6297 | 0.7930 | 0.0004 | 0.0011 | 0.0007 | 0.0010 | 0.0027 | 0.0027 | 0.0064 | 0.0047 | 0.0202 | 0.0199 | 0.0282 | 0.0236 | 0.0285 | 0.0216 | 0.0407 | 0.0308 | 0.8721 | 0.8946 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0028 | 0.0017 | 0.0070 | 0.0091 | 0.0167 | 0.0205 | 0.0423 | 0.0400 | 0.0265 | 0.0377 | 0.0307 | 0.0354 | 0.8721 | 0.8556 | 0.0010 | 0.0016 | 0.0049 | 0.0092 | 0.0191 | 0.0384 | 0.0309 | 0.0427 | 0.8521 | 3 | 5 | 5 | 6 | 7 | 8 | 9 | 11 | 19 | 0.1322 | 0.45 | 1.509 | 0.5124 | 250.6 | 12213 | 813301 | 62700000 | 0.5153 | 0.1526 | 0.0886 | 0.0079 | 0.2162 | 0.0407 | 0.2503 | 0.0797 | 0.2088 | 0.1421 | 0.1362 | 0.1824 | 0.0696 | 0.1959 | 0.0225 | 0.1743 | 0.0078 | 0.1275 | 0.0000 | 0.0493 | 0.0425 | 0.0045 | 0.1012 | 0.0274 | 0.1320 | 0.0540 | 0.1129 | 0.0995 | 0.0975 | 0.1431 | 0.0935 | 0.1554 | 0.0649 | 0.1304 | 0.0728 | 0.1196 | 0.2827 | 0.2662 | 0.0790 | 0.0376 | 0.0515 | 0.0295 | 0.0334 | 0.0302 | 0.0322 | 0.0376 | 0.0632 | 0.0604 | 0.0971 | 0.1150 | 0.0872 | 0.0825 | 0.0989 | 0.1098 | 0.4576 | 0.4974 | 0.1005 | 0.0895 | 0.0781 | 0.0561 | 0.0570 | 0.0875 | 0.0557 | 0.0858 | 0.3897 | ||
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1109 | 467 | | 7728 | 10985 | 187.4 | 61.96 | 106.16 | 170.18 | 109 | 128 | 147 | 169 | 186 | 203 | 220 | 239 | 268 | 0.0861 | 946 | 1.180 | 100.90 | 29.02 | 3 | 0.0294 | 227 | 0.0011 | 27.43 | 7.104 | 0.2644 | 38959.5 | 8810000 | 2140000000 | 549000000000 | 0.4404 | 0.1893 | 0.0019 | 0.0005 | 0.0066 | 0.0013 | 0.0109 | 0.0023 | 0.0241 | 0.0084 | 0.0675 | 0.0240 | 0.0947 | 0.0473 | 0.0944 | 0.0455 | 0.1310 | 0.0624 | 0.5688 | 0.8083 | 0.0006 | 0.0003 | 0.0015 | 0.0009 | 0.0032 | 0.0012 | 0.0043 | 0.0039 | 0.0171 | 0.0115 | 0.0221 | 0.0195 | 0.0225 | 0.0169 | 0.0332 | 0.0232 | 0.8955 | 0.9226 | 0.0028 | 0.0045 | 0.0052 | 0.0034 | 0.0131 | 0.0101 | 0.0197 | 0.0515 | 0.0553 | 0.1074 | 0.0933 | 0.1398 | 0.0778 | 0.1040 | 0.1172 | 0.1275 | 0.6157 | 0.4519 | 0.0003 | 0.0005 | 0.0034 | 0.0120 | 0.0330 | 0.0494 | 0.0546 | 0.0738 | 0.7730 | 10 | 13 | 16 | 20 | 29 | 52 | 97 | 156 | 295 | 0.0735 | 19.46 | 4.540 | 0.5815 | 40229.5 | 25000000 | 19500000000 | 17300000000000 | 0.4726 | 0.1847 | 0.0486 | 0.0029 | 0.0972 | 0.0161 | 0.1627 | 0.0732 | 0.1333 | 0.0992 | 0.1345 | 0.1522 | 0.1390 | 0.1690 | 0.0949 | 0.1107 | 0.0836 | 0.1148 | 0.1062 | 0.2618 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0042 | 0.0027 | 0.0152 | 0.0126 | 0.0576 | 0.0567 | 0.0829 | 0.0680 | 0.0576 | 0.0508 | 0.0880 | 0.0841 | 0.6936 | 0.7242 | 0.0007 | 0.0009 | 0.0045 | 0.0047 | 0.0064 | 0.0108 | 0.0288 | 0.0284 | 0.0804 | 0.0814 | 0.0932 | 0.1063 | 0.0718 | 0.0689 | 0.1044 | 0.1029 | 0.6098 | 0.5958 | 0.0003 | 0.0019 | 0.0055 | 0.0183 | 0.0685 | 0.0985 | 0.0711 | 0.1046 | 0.6313 | ||
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1081 | 145 | | 2712 | 9282 | 475.3 | 160.24 | 36.97 | 64.65 | 263 | 299 | 347 | 418 | 487 | 542 | 587 | 633 | 688 | 0.0873 | 810 | 0.985 | 77.18 | 22.00 | 2 | 0.0686 | 186 | 0.0012 | 27.59 | 6.989 | 0.2409 | 251625.0 | 144000000 | 87200000000 | 54900000000000 | 0.3991 | 0.2354 | 0.0000 | 0.0005 | 0.0023 | 0.0016 | 0.0047 | 0.0016 | 0.0280 | 0.0111 | 0.1145 | 0.0379 | 0.1857 | 0.0779 | 0.1449 | 0.0600 | 0.1694 | 0.0937 | 0.3505 | 0.7158 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0006 | 0.0013 | 0.0028 | 0.0039 | 0.0289 | 0.0210 | 0.0425 | 0.0394 | 0.0289 | 0.0262 | 0.0408 | 0.0398 | 0.8556 | 0.8675 | 0.0011 | 0.0026 | 0.0000 | 0.0078 | 0.0066 | 0.0129 | 0.0198 | 0.0388 | 0.0484 | 0.0775 | 0.0934 | 0.1318 | 0.0780 | 0.1008 | 0.0868 | 0.1421 | 0.6659 | 0.4858 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0348 | 0.0604 | 0.0434 | 0.0519 | 0.8038 | 5 | 6 | 8 | 10 | 12 | 16 | 25 | 47 | 110 | 0.1009 | 8.52 | 3.705 | 0.6389 | 5545.8 | 1750000 | 914000000 | 650000000000 | 0.5399 | 0.1305 | 0.0775 | 0.0094 | 0.1135 | 0.0353 | 0.1658 | 0.0831 | 0.2036 | 0.1160 | 0.1766 | 0.1599 | 0.1423 | 0.1513 | 0.0811 | 0.1528 | 0.0378 | 0.1567 | 0.0018 | 0.1356 | 0.0032 | 0.0027 | 0.0041 | 0.0056 | 0.0105 | 0.0133 | 0.0215 | 0.0245 | 0.0616 | 0.0553 | 0.0859 | 0.0726 | 0.0656 | 0.0709 | 0.0846 | 0.0968 | 0.6630 | 0.6584 | 0.0016 | 0.0017 | 0.0026 | 0.0029 | 0.0078 | 0.0052 | 0.0246 | 0.0310 | 0.0679 | 0.0700 | 0.0878 | 0.0947 | 0.0669 | 0.0729 | 0.0940 | 0.0884 | 0.6468 | 0.6332 | 0.0023 | 0.0023 | 0.0088 | 0.0236 | 0.0634 | 0.0842 | 0.0648 | 0.0851 | 0.6654 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 758 | 118 | | 3722 | 7678 | 368.8 | 182.51 | 164.24 | 272.94 | 145 | 178 | 217 | 266 | 351 | 446 | 510 | 563 | 614 | 0.0847 | 650 | 1.108 | 87.24 | 31.58 | 2 | 0.0623 | 232 | 0.0018 | 10.54 | 6.623 | 0.3115 | 169332.0 | 88000000 | 48900000000 | 28300000000000 | 0.2899 | 0.3386 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0086 | 0.0047 | 0.0310 | 0.0167 | 0.1480 | 0.0670 | 0.2220 | 0.0965 | 0.1463 | 0.0810 | 0.1911 | 0.1186 | 0.2530 | 0.6122 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0010 | 0.0020 | 0.0029 | 0.0035 | 0.0201 | 0.0203 | 0.0315 | 0.0250 | 0.0220 | 0.0238 | 0.0382 | 0.0355 | 0.8844 | 0.8892 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0066 | 0.0149 | 0.0238 | 0.0411 | 0.0416 | 0.0747 | 0.0350 | 0.0691 | 0.0430 | 0.0756 | 0.8500 | 0.7208 | 0.0000 | 0.0000 | 0.0006 | 0.0017 | 0.0251 | 0.0345 | 0.0239 | 0.0395 | 0.8747 | 12 | 17 | 22 | 28 | 43 | 72 | 114 | 240 | 499 | 0.0621 | 27.12 | 4.594 | 0.6002 | 101458.0 | 93500000 | 101000000000 | 118000000000000 | 0.3873 | 0.2579 | 0.0278 | 0.0021 | 0.0732 | 0.0103 | 0.1995 | 0.0372 | 0.1692 | 0.0702 | 0.1843 | 0.1569 | 0.1162 | 0.1610 | 0.0909 | 0.1352 | 0.0707 | 0.1197 | 0.0682 | 0.3075 | 0.0019 | 0.0000 | 0.0014 | 0.0028 | 0.0053 | 0.0035 | 0.0101 | 0.0102 | 0.0483 | 0.0501 | 0.0718 | 0.0654 | 0.0565 | 0.0556 | 0.0775 | 0.0832 | 0.7271 | 0.7292 | 0.0000 | 0.0006 | 0.0041 | 0.0006 | 0.0053 | 0.0026 | 0.0077 | 0.0057 | 0.0543 | 0.0529 | 0.0721 | 0.0861 | 0.0543 | 0.0529 | 0.0874 | 0.0848 | 0.7147 | 0.7136 | 0.0005 | 0.0027 | 0.0086 | 0.0065 | 0.0507 | 0.0706 | 0.0507 | 0.0841 | 0.7256 | ||
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 469 | 438 | | 2983 | 6904 | 291.5 | 155.73 | 25.80 | 36.51 | 163 | 179 | 192 | 210 | 232 | 259 | 292 | 423 | 579 | 0.1047 | 723 | 0.563 | 78.24 | 21.26 | 5 | 0.0865 | 258 | 0.0031 | 12.41 | 6.310 | 0.3653 | 109220.0 | 50500000 | 26800000000 | 15300000000000 | 0.4115 | 0.2245 | 0.0013 | 0.0000 | 0.0013 | 0.0011 | 0.0053 | 0.0049 | 0.0279 | 0.0152 | 0.0810 | 0.0455 | 0.1514 | 0.0829 | 0.1142 | 0.0650 | 0.1116 | 0.0861 | 0.5060 | 0.6994 | 0.0007 | 0.0000 | 0.0007 | 0.0008 | 0.0027 | 0.0036 | 0.0129 | 0.0101 | 0.0278 | 0.0283 | 0.0394 | 0.0449 | 0.0455 | 0.0377 | 0.0502 | 0.0494 | 0.8201 | 0.8251 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0048 | 0.0250 | 0.0353 | 0.0722 | 0.0609 | 0.0222 | 0.0304 | 0.0431 | 0.0529 | 0.8333 | 0.8157 | 0.0000 | 0.0022 | 0.0078 | 0.0100 | 0.0288 | 0.0654 | 0.0310 | 0.0488 | 0.8060 | 7 | 9 | 10 | 12 | 14 | 17 | 22 | 30 | 49 | 0.1051 | 1.66 | 3.110 | 0.7374 | 1998.1 | 320182 | 69200000 | 17600000000 | 0.5249 | 0.1326 | 0.0229 | 0.0158 | 0.0439 | 0.0273 | 0.0768 | 0.0379 | 0.1286 | 0.0532 | 0.1655 | 0.0873 | 0.1864 | 0.1237 | 0.1685 | 0.1324 | 0.1256 | 0.1938 | 0.0818 | 0.3285 | 0.0053 | 0.0100 | 0.0107 | 0.0158 | 0.0191 | 0.0197 | 0.0364 | 0.0262 | 0.0631 | 0.0494 | 0.1039 | 0.0862 | 0.0795 | 0.0733 | 0.0955 | 0.1172 | 0.5866 | 0.6021 | 0.0056 | 0.0129 | 0.0104 | 0.0069 | 0.0288 | 0.0247 | 0.0400 | 0.0366 | 0.0737 | 0.0791 | 0.1017 | 0.1098 | 0.0745 | 0.0692 | 0.1129 | 0.0930 | 0.5524 | 0.5678 | 0.0070 | 0.0152 | 0.0275 | 0.0427 | 0.0719 | 0.1029 | 0.0830 | 0.0918 | 0.5582 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 487 | 388 | | 17803 | 45389 | 157.0 | 50.28 | 154.36 | 177.24 | 92 | 114 | 128 | 142 | 155 | 168 | 183 | 200 | 225 | 0.0425 | 1928 | 1.251 | 24.52 | 7.81 | 5 | 0.0033 | 58 | 0.0011 | 27.12 | 7.140 | 0.2383 | 27189.4 | 5090000 | 1010000000 | 213000000000 | 0.4282 | 0.2106 | 0.0016 | 0.0001 | 0.0027 | 0.0011 | 0.0080 | 0.0022 | 0.0288 | 0.0083 | 0.0923 | 0.0292 | 0.1552 | 0.0530 | 0.1536 | 0.0615 | 0.1813 | 0.0892 | 0.3764 | 0.7554 | 0.0006 | 0.0001 | 0.0008 | 0.0008 | 0.0020 | 0.0012 | 0.0062 | 0.0038 | 0.0238 | 0.0118 | 0.0466 | 0.0193 | 0.0520 | 0.0202 | 0.0673 | 0.0299 | 0.8006 | 0.9130 | 0.0028 | 0.0076 | 0.0051 | 0.0076 | 0.0145 | 0.0286 | 0.0373 | 0.0753 | 0.0821 | 0.1201 | 0.1345 | 0.1711 | 0.1117 | 0.1287 | 0.1381 | 0.1368 | 0.4740 | 0.3241 | 0.0009 | 0.0019 | 0.0057 | 0.0186 | 0.0505 | 0.0897 | 0.0859 | 0.1121 | 0.6346 | 13 | 18 | 26 | 47 | 81 | 128 | 193 | 278 | 407 | 0.0395 | 20.75 | 5.394 | 0.5005 | 55240.7 | 27700000 | 16900000000 | 11900000000000 | 0.4247 | 0.2143 | 0.0378 | 0.0014 | 0.1492 | 0.0110 | 0.2622 | 0.0683 | 0.1893 | 0.1171 | 0.1504 | 0.1913 | 0.1095 | 0.1978 | 0.0586 | 0.1383 | 0.0341 | 0.1296 | 0.0088 | 0.1451 | 0.0003 | 0.0002 | 0.0011 | 0.0008 | 0.0022 | 0.0018 | 0.0130 | 0.0095 | 0.0518 | 0.0406 | 0.0919 | 0.0720 | 0.0661 | 0.0535 | 0.0987 | 0.0822 | 0.6750 | 0.7394 | 0.0006 | 0.0006 | 0.0012 | 0.0024 | 0.0051 | 0.0080 | 0.0184 | 0.0254 | 0.0735 | 0.0834 | 0.1248 | 0.1314 | 0.0862 | 0.0949 | 0.1190 | 0.1284 | 0.5712 | 0.5254 | 0.0004 | 0.0015 | 0.0030 | 0.0169 | 0.0596 | 0.1071 | 0.0813 | 0.1092 | 0.6210 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 632 | 365 | | 4889 | 13256 | 383.0 | 256.14 | 34.30 | 57.66 | 183 | 197 | 211 | 228 | 257 | 316 | 420 | 590 | 842 | 0.0671 | 890 | 0.504 | 95.59 | 26.87 | 10 | 0.0714 | 349 | 0.0027 | 26.56 | 6.768 | 0.3301 | 212277.0 | 153000000 | 126000000000 | 111000000000000 | 0.4295 | 0.1988 | 0.0014 | 0.0022 | 0.0000 | 0.0011 | 0.0177 | 0.0092 | 0.0477 | 0.0152 | 0.1376 | 0.0656 | 0.2030 | 0.1062 | 0.1444 | 0.0846 | 0.1253 | 0.1084 | 0.3229 | 0.6076 | 0.0000 | 0.0014 | 0.0000 | 0.0007 | 0.0010 | 0.0058 | 0.0030 | 0.0093 | 0.0272 | 0.0319 | 0.0495 | 0.0436 | 0.0302 | 0.0367 | 0.0475 | 0.0480 | 0.8417 | 0.8226 | 0.0000 | 0.0019 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0070 | 0.0056 | 0.0396 | 0.0318 | 0.0591 | 0.0589 | 0.0311 | 0.0308 | 0.0521 | 0.0421 | 0.8073 | 0.8290 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0325 | 0.0644 | 0.0319 | 0.0576 | 0.8081 | 6 | 7 | 9 | 11 | 13 | 17 | 25 | 40 | 85 | 0.1143 | 7.18 | 3.518 | 0.6992 | 4501.5 | 1130000 | 367000000 | 138000000000 | 0.5010 | 0.1794 | 0.0284 | 0.0102 | 0.0869 | 0.0191 | 0.1446 | 0.0339 | 0.1683 | 0.0750 | 0.1629 | 0.1280 | 0.1299 | 0.1522 | 0.1034 | 0.1314 | 0.1052 | 0.1526 | 0.0704 | 0.2976 | 0.0040 | 0.0039 | 0.0059 | 0.0071 | 0.0075 | 0.0092 | 0.0215 | 0.0184 | 0.0557 | 0.0417 | 0.0796 | 0.0708 | 0.0632 | 0.0565 | 0.0866 | 0.0877 | 0.6759 | 0.7047 | 0.0019 | 0.0022 | 0.0019 | 0.0013 | 0.0095 | 0.0056 | 0.0175 | 0.0233 | 0.0712 | 0.0739 | 0.1086 | 0.1188 | 0.0712 | 0.0774 | 0.1036 | 0.1059 | 0.6145 | 0.5916 | 0.0032 | 0.0064 | 0.0051 | 0.0185 | 0.0543 | 0.1006 | 0.0716 | 0.1016 | 0.6387 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 301 | 366 | | 6423 | 26442 | 283.5 | 88.59 | 136.46 | 161.23 | 181 | 203 | 226 | 250 | 273 | 298 | 324 | 354 | 403 | 0.0445 | 1176 | 1.048 | 155.22 | 58.08 | 2 | 0.0629 | 404 | 0.0011 | 32.72 | 7.058 | 0.2184 | 88205.5 | 29900000 | 10900000000 | 4280000000000 | 0.4253 | 0.2195 | 0.0007 | 0.0000 | 0.0034 | 0.0009 | 0.0146 | 0.0032 | 0.0409 | 0.0087 | 0.0940 | 0.0368 | 0.1492 | 0.0716 | 0.1359 | 0.0612 | 0.1683 | 0.0927 | 0.3931 | 0.7248 | 0.0002 | 0.0000 | 0.0009 | 0.0007 | 0.0040 | 0.0017 | 0.0105 | 0.0042 | 0.0296 | 0.0204 | 0.0525 | 0.0362 | 0.0423 | 0.0262 | 0.0710 | 0.0400 | 0.7891 | 0.8707 | 0.0013 | 0.0070 | 0.0064 | 0.0098 | 0.0135 | 0.0209 | 0.0411 | 0.0809 | 0.1046 | 0.1492 | 0.1380 | 0.1618 | 0.1014 | 0.1213 | 0.1444 | 0.1269 | 0.4493 | 0.3222 | 0.0000 | 0.0020 | 0.0040 | 0.0131 | 0.0529 | 0.0827 | 0.0844 | 0.1138 | 0.6471 | 9 | 14 | 24 | 38 | 66 | 107 | 167 | 252 | 373 | 0.0462 | 12.01 | 4.985 | 0.5301 | 44615.1 | 20200000 | 11100000000 | 6860000000000 | 0.4314 | 0.2136 | 0.0461 | 0.0018 | 0.1520 | 0.0172 | 0.2501 | 0.0918 | 0.1590 | 0.1281 | 0.1504 | 0.1891 | 0.1005 | 0.1767 | 0.0606 | 0.1214 | 0.0494 | 0.1181 | 0.0317 | 0.1558 | 0.0002 | 0.0002 | 0.0001 | 0.0004 | 0.0016 | 0.0014 | 0.0128 | 0.0100 | 0.0523 | 0.0437 | 0.0925 | 0.0734 | 0.0653 | 0.0565 | 0.0976 | 0.0819 | 0.6777 | 0.7324 | 0.0001 | 0.0006 | 0.0009 | 0.0013 | 0.0036 | 0.0042 | 0.0155 | 0.0196 | 0.0730 | 0.0822 | 0.1241 | 0.1392 | 0.0858 | 0.0894 | 0.1200 | 0.1337 | 0.5771 | 0.5298 | 0.0001 | 0.0005 | 0.0029 | 0.0149 | 0.0623 | 0.1047 | 0.0750 | 0.1099 | 0.6295 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 925 | 483 | | 3069 | 17112 | 133.0 | 40.22 | 103.86 | 203.05 | 76 | 97 | 114 | 125 | 135 | 144 | 156 | 169 | 185 | 0.0464 | 794 | 0.346 | 113.00 | 13.45 | 1 | 0.1036 | 318 | 0.0020 | 15.03 | 6.464 | 0.2683 | 19308.7 | 2990000 | 486000000 | 82200000000 | 0.3770 | 0.2497 | 0.0000 | 0.0000 | 0.0061 | 0.0008 | 0.0067 | 0.0008 | 0.0223 | 0.0066 | 0.0756 | 0.0370 | 0.1201 | 0.0555 | 0.1066 | 0.0588 | 0.1296 | 0.0867 | 0.5331 | 0.7538 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0004 | 0.0004 | 0.0065 | 0.0033 | 0.0230 | 0.0218 | 0.0390 | 0.0336 | 0.0295 | 0.0251 | 0.0464 | 0.0369 | 0.8553 | 0.8783 | 0.0000 | 0.0072 | 0.0036 | 0.0036 | 0.0109 | 0.0324 | 0.0339 | 0.0755 | 0.0593 | 0.1547 | 0.1186 | 0.1007 | 0.1005 | 0.1583 | 0.1223 | 0.1151 | 0.5508 | 0.3525 | 0.0006 | 0.0006 | 0.0031 | 0.0161 | 0.0433 | 0.0644 | 0.0718 | 0.0934 | 0.7067 | 11 | 13 | 16 | 21 | 29 | 46 | 76 | 134 | 243 | 0.0626 | 20.97 | 4.597 | 0.5710 | 52014.4 | 50700000 | 63400000000 | 88800000000000 | 0.5552 | 0.1464 | 0.0385 | 0.0020 | 0.1709 | 0.0137 | 0.2873 | 0.1186 | 0.1533 | 0.1182 | 0.1415 | 0.1703 | 0.1114 | 0.2121 | 0.0427 | 0.1186 | 0.0369 | 0.1014 | 0.0176 | 0.1452 | 0.0004 | 0.0007 | 0.0010 | 0.0017 | 0.0045 | 0.0040 | 0.0170 | 0.0154 | 0.0622 | 0.0508 | 0.1379 | 0.1125 | 0.0614 | 0.0648 | 0.0821 | 0.0786 | 0.6335 | 0.6716 | 0.0014 | 0.0009 | 0.0049 | 0.0060 | 0.0140 | 0.0158 | 0.0198 | 0.0211 | 0.0673 | 0.0687 | 0.1389 | 0.1378 | 0.0579 | 0.0627 | 0.0826 | 0.0880 | 0.6132 | 0.5990 | 0.0005 | 0.0036 | 0.0082 | 0.0192 | 0.0694 | 0.1387 | 0.0634 | 0.0742 | 0.6229 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 876 | | 4650 | 27974 | 298.2 | 83.39 | 212.92 | 186.19 | 196 | 225 | 246 | 269 | 291 | 315 | 341 | 374 | 413 | 0.0507 | 1418 | 1.135 | 46.75 | 17.00 | 6 | 0.0265 | 123 | 0.0006 | 64.25 | 7.641 | 0.1408 | 95900.4 | 32900000 | 11900000000 | 4530000000000 | 0.4875 | 0.1659 | 0.0004 | 0.0000 | 0.0022 | 0.0008 | 0.0057 | 0.0008 | 0.0284 | 0.0091 | 0.1091 | 0.0467 | 0.1916 | 0.0965 | 0.1414 | 0.0657 | 0.1689 | 0.1033 | 0.3522 | 0.6771 | 0.0000 | 0.0000 | 0.0009 | 0.0007 | 0.0020 | 0.0000 | 0.0128 | 0.0059 | 0.0483 | 0.0320 | 0.0762 | 0.0692 | 0.0556 | 0.0391 | 0.0829 | 0.0608 | 0.7213 | 0.7923 | 0.0017 | 0.0048 | 0.0035 | 0.0095 | 0.0096 | 0.0263 | 0.0192 | 0.0668 | 0.0925 | 0.1265 | 0.1187 | 0.1384 | 0.0855 | 0.1289 | 0.1309 | 0.1480 | 0.5384 | 0.3508 | 0.0014 | 0.0009 | 0.0059 | 0.0237 | 0.0702 | 0.0916 | 0.0766 | 0.0861 | 0.6436 | 27 | 52 | 83 | 117 | 157 | 208 | 270 | 356 | 482 | 0.0050 | 46.50 | 6.695 | 0.3231 | 79998.9 | 40100000 | 24000000000 | 16200000000000 | 0.4940 | 0.1623 | 0.0270 | 0.0010 | 0.1183 | 0.0111 | 0.2093 | 0.0488 | 0.1802 | 0.0945 | 0.1620 | 0.1643 | 0.1329 | 0.2010 | 0.0821 | 0.1517 | 0.0530 | 0.1382 | 0.0352 | 0.1895 | 0.0007 | 0.0001 | 0.0014 | 0.0010 | 0.0042 | 0.0026 | 0.0218 | 0.0137 | 0.0642 | 0.0508 | 0.1052 | 0.0828 | 0.0816 | 0.0668 | 0.1081 | 0.0927 | 0.6129 | 0.6894 | 0.0013 | 0.0016 | 0.0028 | 0.0069 | 0.0105 | 0.0144 | 0.0378 | 0.0507 | 0.0975 | 0.1038 | 0.1384 | 0.1575 | 0.1063 | 0.1060 | 0.1287 | 0.1379 | 0.4767 | 0.4212 | 0.0009 | 0.0024 | 0.0075 | 0.0292 | 0.0795 | 0.1238 | 0.0924 | 0.1217 | 0.5426 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 958 | 125 | | 2932 | 10604 | 196.6 | 65.96 | 9.01 | 4.41 | 127 | 138 | 150 | 164 | 179 | 198 | 223 | 249 | 301 | 0.0658 | 698 | 0.614 | 76.01 | 21.95 | 1 | 0.0836 | 245 | 0.0079 | 2.74 | 5.180 | 0.5006 | 42980.6 | 10400000 | 2760000000 | 788000000000 | 0.4076 | 0.2304 | 0.0043 | 0.0013 | 0.0035 | 0.0013 | 0.0112 | 0.0042 | 0.0371 | 0.0097 | 0.0569 | 0.0295 | 0.1320 | 0.0687 | 0.1217 | 0.0442 | 0.1639 | 0.0720 | 0.4694 | 0.7692 | 0.0021 | 0.0011 | 0.0021 | 0.0007 | 0.0053 | 0.0032 | 0.0137 | 0.0064 | 0.0217 | 0.0207 | 0.0455 | 0.0454 | 0.0418 | 0.0264 | 0.0561 | 0.0482 | 0.8117 | 0.8477 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0109 | 0.0047 | 0.0301 | 0.0165 | 0.0342 | 0.0425 | 0.0861 | 0.0778 | 0.0697 | 0.0472 | 0.0765 | 0.0802 | 0.6899 | 0.7311 | 0.0017 | 0.0025 | 0.0042 | 0.0151 | 0.0260 | 0.0519 | 0.0511 | 0.0611 | 0.7864 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 14 | 0.0111 | 13.72 | 5.076 | 0.3038 | 100.7 | 1416.1 | 25055.2 | 539238 | 0.4587 | 0.1802 | 0.0400 | 0.0040 | 0.1247 | 0.0070 | 0.2092 | 0.0206 | 0.2582 | 0.0465 | 0.1991 | 0.1010 | 0.1141 | 0.1792 | 0.0447 | 0.2550 | 0.0098 | 0.2595 | 0.0003 | 0.1273 | 0.0087 | 0.0002 | 0.0392 | 0.0012 | 0.0841 | 0.0078 | 0.1282 | 0.0233 | 0.1444 | 0.0654 | 0.1470 | 0.1201 | 0.1169 | 0.1781 | 0.1209 | 0.2377 | 0.2107 | 0.3662 | 0.1147 | 0.1071 | 0.0900 | 0.0750 | 0.0862 | 0.0679 | 0.0718 | 0.0968 | 0.0938 | 0.0859 | 0.1045 | 0.1000 | 0.0836 | 0.1019 | 0.0957 | 0.1167 | 0.2595 | 0.2487 | 0.0483 | 0.0956 | 0.1102 | 0.1089 | 0.1085 | 0.0986 | 0.0902 | 0.1128 | 0.2269 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 407 | 716 | | 7114 | 12770 | 534.1 | 94.65 | 61.96 | 146.06 | 380 | 451 | 508 | 534 | 555 | 577 | 594 | 611 | 633 | 0.0662 | 846 | 0.850 | 97.59 | 26.25 | 2 | 0.0417 | 297 | 0.0011 | 32.30 | 7.208 | 0.2276 | 294243.0 | 166000000 | 95600000000 | 55900000000000 | 0.4540 | 0.2027 | 0.0002 | 0.0001 | 0.0009 | 0.0006 | 0.0015 | 0.0003 | 0.0052 | 0.0017 | 0.0232 | 0.0121 | 0.0462 | 0.0176 | 0.0420 | 0.0150 | 0.0641 | 0.0232 | 0.8167 | 0.9294 | 0.0002 | 0.0001 | 0.0003 | 0.0006 | 0.0002 | 0.0003 | 0.0007 | 0.0017 | 0.0128 | 0.0121 | 0.0245 | 0.0176 | 0.0130 | 0.0150 | 0.0239 | 0.0232 | 0.9245 | 0.9294 | 0.0121 | 0.0000 | 0.0208 | 0.0000 | 0.0363 | 0.0000 | 0.0813 | 0.0000 | 0.1142 | 0.0000 | 0.1280 | 0.0000 | 0.1090 | 0.0000 | 0.1228 | 0.0000 | 0.3754 | 0.0000 | 0.0005 | 0.0014 | 0.0054 | 0.0119 | 0.0261 | 0.0428 | 0.0447 | 0.0612 | 0.8061 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 33 | 165 | 0.1905 | 3.26 | 2.362 | 0.6175 | 25171.9 | 16600000 | 13100000000 | 11600000000000 | 0.6507 | 0.0699 | 0.0193 | 0.0057 | 0.1322 | 0.0086 | 0.2204 | 0.0743 | 0.1736 | 0.1329 | 0.1267 | 0.2157 | 0.0909 | 0.1571 | 0.0716 | 0.0929 | 0.0661 | 0.1114 | 0.0992 | 0.2014 | 0.0000 | 0.0008 | 0.0009 | 0.0008 | 0.0031 | 0.0028 | 0.0098 | 0.0102 | 0.0459 | 0.0468 | 0.0570 | 0.0533 | 0.0459 | 0.0403 | 0.0731 | 0.0744 | 0.7643 | 0.7706 | 0.0011 | 0.0006 | 0.0021 | 0.0017 | 0.0069 | 0.0040 | 0.0133 | 0.0108 | 0.0436 | 0.0483 | 0.0760 | 0.0802 | 0.0452 | 0.0495 | 0.0803 | 0.0870 | 0.7315 | 0.7180 | 0.0005 | 0.0019 | 0.0048 | 0.0150 | 0.0446 | 0.0650 | 0.0509 | 0.0805 | 0.7368 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 309 | 735 | | 1819 | 14901 | 73.2 | 15.19 | 136.21 | 157.45 | 56 | 62 | 65 | 67 | 70 | 74 | 79 | 85 | 94 | 0.0571 | 851 | 0.961 | 66.85 | 20.22 | 3 | 0.0995 | 181 | 0.0042 | 13.83 | 5.799 | 0.2858 | 5584.7 | 444991 | 37000000 | 3220000000 | 0.5015 | 0.1554 | 0.0008 | 0.0000 | 0.0047 | 0.0006 | 0.0228 | 0.0012 | 0.0417 | 0.0140 | 0.1133 | 0.0450 | 0.1707 | 0.1040 | 0.1526 | 0.0900 | 0.1794 | 0.1244 | 0.3139 | 0.6209 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0069 | 0.0011 | 0.0202 | 0.0117 | 0.0656 | 0.0362 | 0.1040 | 0.0841 | 0.0807 | 0.0523 | 0.1230 | 0.0885 | 0.5984 | 0.7255 | 0.0095 | 0.0238 | 0.0063 | 0.0357 | 0.0381 | 0.1190 | 0.1175 | 0.2381 | 0.1460 | 0.1905 | 0.2190 | 0.1429 | 0.1238 | 0.0833 | 0.1143 | 0.0833 | 0.2254 | 0.0833 | 0.0025 | 0.0135 | 0.0197 | 0.0492 | 0.1095 | 0.1365 | 0.1267 | 0.1501 | 0.3924 | 14 | 17 | 23 | 40 | 73 | 110 | 160 | 243 | 367 | 0.0319 | 18.03 | 5.311 | 0.4923 | 43340.4 | 19300000 | 10300000000 | 6180000000000 | 0.4512 | 0.1992 | 0.0348 | 0.0006 | 0.1211 | 0.0135 | 0.2124 | 0.0737 | 0.1696 | 0.0995 | 0.1621 | 0.1575 | 0.1286 | 0.1894 | 0.0776 | 0.1317 | 0.0547 | 0.1357 | 0.0391 | 0.1983 | 0.0008 | 0.0000 | 0.0012 | 0.0006 | 0.0050 | 0.0021 | 0.0163 | 0.0107 | 0.0553 | 0.0478 | 0.0947 | 0.0811 | 0.0696 | 0.0552 | 0.0962 | 0.0929 | 0.6610 | 0.7096 | 0.0009 | 0.0008 | 0.0018 | 0.0024 | 0.0075 | 0.0050 | 0.0218 | 0.0214 | 0.0693 | 0.0833 | 0.1160 | 0.1303 | 0.0869 | 0.0844 | 0.1141 | 0.1295 | 0.5816 | 0.5430 | 0.0008 | 0.0010 | 0.0031 | 0.0189 | 0.0617 | 0.1060 | 0.0742 | 0.1094 | 0.6249 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1125 | 294 | | 3689 | 5640 | 111.6 | 32.45 | 209.00 | 240.70 | 71 | 82 | 92 | 101 | 109 | 118 | 128 | 138 | 154 | 0.1225 | 691 | 1.145 | 36.89 | 14.32 | 4 | 0.0268 | 99 | 0.0011 | 36.53 | 6.994 | 0.1873 | 13497.5 | 1760000 | 244000000 | 36000000000 | 0.4226 | 0.2234 | 0.0011 | 0.0003 | 0.0055 | 0.0006 | 0.0082 | 0.0023 | 0.0448 | 0.0074 | 0.1055 | 0.0366 | 0.1393 | 0.0563 | 0.1650 | 0.0738 | 0.1984 | 0.1039 | 0.3322 | 0.7187 | 0.0007 | 0.0003 | 0.0026 | 0.0006 | 0.0022 | 0.0012 | 0.0137 | 0.0056 | 0.0290 | 0.0222 | 0.0475 | 0.0275 | 0.0561 | 0.0333 | 0.0750 | 0.0447 | 0.7732 | 0.8647 | 0.0046 | 0.0120 | 0.0174 | 0.0090 | 0.0231 | 0.0270 | 0.0556 | 0.1261 | 0.1088 | 0.1411 | 0.1574 | 0.1952 | 0.1088 | 0.1111 | 0.1586 | 0.1441 | 0.3657 | 0.2342 | 0.0029 | 0.0029 | 0.0080 | 0.0264 | 0.0568 | 0.0998 | 0.1096 | 0.1234 | 0.5703 | 25 | 37 | 55 | 75 | 103 | 150 | 232 | 361 | 559 | 0.0196 | 21.82 | 5.398 | 0.4816 | 101607.0 | 71300000 | 60000000000 | 56400000000000 | 0.6220 | 0.0932 | 0.0428 | 0.0027 | 0.1732 | 0.0150 | 0.3230 | 0.0707 | 0.2043 | 0.1405 | 0.1012 | 0.2102 | 0.0700 | 0.2191 | 0.0389 | 0.1104 | 0.0253 | 0.1051 | 0.0214 | 0.1263 | 0.0000 | 0.0008 | 0.0014 | 0.0008 | 0.0028 | 0.0040 | 0.0247 | 0.0127 | 0.0669 | 0.0618 | 0.1125 | 0.0907 | 0.0807 | 0.0713 | 0.1210 | 0.1125 | 0.5899 | 0.6455 | 0.0006 | 0.0014 | 0.0013 | 0.0022 | 0.0050 | 0.0086 | 0.0264 | 0.0402 | 0.0866 | 0.0782 | 0.1281 | 0.1407 | 0.1017 | 0.1070 | 0.1318 | 0.1386 | 0.5185 | 0.4831 | 0.0006 | 0.0011 | 0.0044 | 0.0237 | 0.0860 | 0.1113 | 0.0970 | 0.1333 | 0.5427 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 |