High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 443 | 181 | | 15600 | 34303 | 188.2 | 54.70 | 154.95 | 208.03 | 119 | 143 | 160 | 175 | 188 | 201 | 216 | 233 | 258 | 0.0475 | 1631 | 1.299 | 27.66 | 11.00 | 2 | 0.0046 | 72 | 0.0004 | 108.38 | 8.177 | 0.1198 | 38397.0 | 8360000 | 1930000000 | 466000000000 | 0.4679 | 0.1823 | 0.0004 | 0.0001 | 0.0026 | 0.0001 | 0.0097 | 0.0012 | 0.0358 | 0.0053 | 0.0933 | 0.0269 | 0.1554 | 0.0528 | 0.1646 | 0.0630 | 0.1873 | 0.0910 | 0.3510 | 0.7598 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0023 | 0.0002 | 0.0099 | 0.0029 | 0.0301 | 0.0153 | 0.0539 | 0.0244 | 0.0604 | 0.0263 | 0.0836 | 0.0395 | 0.7594 | 0.8915 | 0.0043 | 0.0083 | 0.0062 | 0.0113 | 0.0231 | 0.0354 | 0.0593 | 0.1032 | 0.1094 | 0.1620 | 0.1512 | 0.1809 | 0.1215 | 0.1281 | 0.1357 | 0.1326 | 0.3894 | 0.2381 | 0.0015 | 0.0030 | 0.0071 | 0.0246 | 0.0622 | 0.0965 | 0.0932 | 0.1282 | 0.5835 | 16 | 20 | 27 | 40 | 62 | 106 | 174 | 266 | 412 | 0.0628 | 20.08 | 4.869 | 0.5440 | 67285.9 | 49100000 | 50400000000 | 64700000000000 | 0.4173 | 0.2427 | 0.0913 | 0.0020 | 0.2477 | 0.0254 | 0.3084 | 0.1572 | 0.1589 | 0.1986 | 0.0885 | 0.2038 | 0.0561 | 0.1589 | 0.0310 | 0.1065 | 0.0129 | 0.0838 | 0.0052 | 0.0638 | 0.0002 | 0.0001 | 0.0005 | 0.0000 | 0.0017 | 0.0015 | 0.0143 | 0.0116 | 0.0709 | 0.0573 | 0.1133 | 0.0932 | 0.0852 | 0.0701 | 0.1288 | 0.1064 | 0.5851 | 0.6598 | 0.0006 | 0.0005 | 0.0015 | 0.0023 | 0.0063 | 0.0108 | 0.0215 | 0.0289 | 0.0926 | 0.1079 | 0.1548 | 0.1646 | 0.1067 | 0.1186 | 0.1497 | 0.1513 | 0.4664 | 0.4151 | 0.0004 | 0.0008 | 0.0032 | 0.0197 | 0.0800 | 0.1330 | 0.1011 | 0.1397 | 0.5221 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 541 | 522 | | 7538 | 10729 | 182.1 | 53.16 | 151.55 | 105.15 | 123 | 138 | 150 | 162 | 173 | 185 | 200 | 220 | 253 | 0.0842 | 903 | 1.033 | 124.56 | 28.32 | 1 | 0.0358 | 270 | 0.0011 | 47.33 | 7.166 | 0.1859 | 35971.8 | 7740000 | 1820000000 | 464000000000 | 0.4607 | 0.1986 | 0.0008 | 0.0002 | 0.0033 | 0.0003 | 0.0110 | 0.0014 | 0.0358 | 0.0038 | 0.1099 | 0.0259 | 0.1983 | 0.0649 | 0.1693 | 0.0640 | 0.1888 | 0.0978 | 0.2827 | 0.7419 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0075 | 0.0010 | 0.0464 | 0.0143 | 0.0907 | 0.0329 | 0.0762 | 0.0285 | 0.1180 | 0.0474 | 0.6588 | 0.8759 | 0.0038 | 0.0055 | 0.0070 | 0.0083 | 0.0203 | 0.0290 | 0.0725 | 0.0981 | 0.1462 | 0.1630 | 0.1697 | 0.2003 | 0.1132 | 0.1077 | 0.1373 | 0.1436 | 0.3299 | 0.2445 | 0.0003 | 0.0050 | 0.0050 | 0.0400 | 0.1026 | 0.1488 | 0.1079 | 0.1417 | 0.4487 | 38 | 59 | 80 | 102 | 128 | 157 | 190 | 236 | 297 | 0.0020 | 46.88 | 6.872 | 0.2760 | 34024.8 | 9800000 | 3360000000 | 1320000000000 | 0.5574 | 0.1310 | 0.0165 | 0.0000 | 0.1056 | 0.0050 | 0.2130 | 0.0382 | 0.1703 | 0.0893 | 0.1387 | 0.1551 | 0.1488 | 0.2086 | 0.0826 | 0.1535 | 0.0716 | 0.1259 | 0.0528 | 0.2244 | 0.0005 | 0.0000 | 0.0002 | 0.0006 | 0.0020 | 0.0016 | 0.0138 | 0.0112 | 0.0620 | 0.0424 | 0.1227 | 0.0865 | 0.0888 | 0.0730 | 0.1299 | 0.1037 | 0.5802 | 0.6811 | 0.0006 | 0.0004 | 0.0029 | 0.0049 | 0.0119 | 0.0162 | 0.0365 | 0.0503 | 0.1192 | 0.1521 | 0.1812 | 0.1923 | 0.1190 | 0.1367 | 0.1520 | 0.1559 | 0.3768 | 0.2911 | 0.0002 | 0.0009 | 0.0049 | 0.0238 | 0.0980 | 0.1462 | 0.1128 | 0.1557 | 0.4576 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 536 | 592 | | 11784 | 41678 | 115.6 | 34.59 | 207.83 | 214.61 | 75 | 86 | 94 | 103 | 111 | 120 | 130 | 144 | 163 | 0.0416 | 1732 | 0.727 | 154.55 | 39.40 | 3 | 0.0386 | 455 | 0.0021 | 19.63 | 6.518 | 0.2766 | 14550.8 | 1990000 | 293000000 | 46400000000 | 0.4899 | 0.1699 | 0.0021 | 0.0004 | 0.0048 | 0.0007 | 0.0141 | 0.0032 | 0.0416 | 0.0077 | 0.1062 | 0.0329 | 0.1621 | 0.0738 | 0.1591 | 0.0708 | 0.1647 | 0.0991 | 0.3453 | 0.7113 | 0.0007 | 0.0001 | 0.0018 | 0.0005 | 0.0040 | 0.0013 | 0.0122 | 0.0039 | 0.0406 | 0.0176 | 0.0687 | 0.0392 | 0.0628 | 0.0280 | 0.0796 | 0.0464 | 0.7295 | 0.8631 | 0.0022 | 0.0025 | 0.0041 | 0.0115 | 0.0137 | 0.0329 | 0.0504 | 0.0873 | 0.1067 | 0.1853 | 0.1530 | 0.1919 | 0.1278 | 0.1227 | 0.1467 | 0.1524 | 0.3956 | 0.2133 | 0.0013 | 0.0036 | 0.0085 | 0.0266 | 0.0690 | 0.1142 | 0.0929 | 0.1140 | 0.5699 | 15 | 20 | 37 | 80 | 139 | 203 | 278 | 375 | 515 | 0.0215 | 74.38 | 6.685 | 0.3397 | 89248.9 | 51000000 | 34800000000 | 27200000000000 | 0.4252 | 0.2362 | 0.0235 | 0.0012 | 0.1173 | 0.0073 | 0.2179 | 0.0568 | 0.1485 | 0.1081 | 0.1623 | 0.1648 | 0.1467 | 0.2023 | 0.0826 | 0.1340 | 0.0615 | 0.1331 | 0.0396 | 0.1923 | 0.0003 | 0.0001 | 0.0006 | 0.0004 | 0.0028 | 0.0018 | 0.0089 | 0.0066 | 0.0493 | 0.0407 | 0.0985 | 0.0784 | 0.0722 | 0.0592 | 0.0927 | 0.0831 | 0.6748 | 0.7298 | 0.0013 | 0.0008 | 0.0022 | 0.0025 | 0.0046 | 0.0081 | 0.0169 | 0.0211 | 0.0664 | 0.0802 | 0.1232 | 0.1307 | 0.0875 | 0.0958 | 0.1112 | 0.1158 | 0.5867 | 0.5449 | 0.0005 | 0.0023 | 0.0051 | 0.0144 | 0.0596 | 0.1114 | 0.0778 | 0.1061 | 0.6229 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1270 | 935 | | 2332 | 2784 | 77.0 | 17.41 | 147.31 | 171.19 | 57 | 63 | 67 | 71 | 75 | 79 | 84 | 90 | 98 | 0.1566 | 436 | 0.850 | 77.94 | 29.70 | 1 | 0.1038 | 242 | 0.0063 | 9.67 | 5.383 | 0.3501 | 6226.1 | 531430 | 48100000 | 4640000000 | 0.4627 | 0.1874 | 0.0013 | 0.0000 | 0.0038 | 0.0005 | 0.0089 | 0.0014 | 0.0335 | 0.0046 | 0.0772 | 0.0246 | 0.1392 | 0.0483 | 0.1512 | 0.0433 | 0.1980 | 0.0724 | 0.3871 | 0.8050 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0031 | 0.0000 | 0.0098 | 0.0013 | 0.0411 | 0.0183 | 0.0878 | 0.0404 | 0.0734 | 0.0243 | 0.1145 | 0.0469 | 0.6689 | 0.8688 | 0.0109 | 0.0189 | 0.0327 | 0.0189 | 0.0463 | 0.0566 | 0.1308 | 0.1509 | 0.1417 | 0.1887 | 0.1989 | 0.2264 | 0.1144 | 0.0943 | 0.1608 | 0.1321 | 0.1635 | 0.1132 | 0.0028 | 0.0123 | 0.0274 | 0.0482 | 0.1154 | 0.1703 | 0.1060 | 0.1552 | 0.3623 | 13 | 16 | 21 | 34 | 74 | 129 | 190 | 273 | 377 | 0.0284 | 57.62 | 5.532 | 0.4008 | 50997.4 | 24600000 | 14500000000 | 9660000000000 | 0.5052 | 0.1542 | 0.0789 | 0.0074 | 0.2366 | 0.0391 | 0.2258 | 0.1657 | 0.1075 | 0.1304 | 0.1004 | 0.1657 | 0.1183 | 0.1657 | 0.0824 | 0.1229 | 0.0323 | 0.0838 | 0.0179 | 0.1192 | 0.0017 | 0.0000 | 0.0017 | 0.0008 | 0.0051 | 0.0084 | 0.0146 | 0.0114 | 0.0788 | 0.0729 | 0.1311 | 0.1109 | 0.0874 | 0.0858 | 0.1482 | 0.1291 | 0.5313 | 0.5809 | 0.0011 | 0.0000 | 0.0045 | 0.0064 | 0.0124 | 0.0141 | 0.0236 | 0.0295 | 0.1025 | 0.1013 | 0.1577 | 0.1782 | 0.1092 | 0.1115 | 0.1441 | 0.1449 | 0.4448 | 0.4141 | 0.0020 | 0.0039 | 0.0039 | 0.0225 | 0.1000 | 0.1324 | 0.1049 | 0.1471 | 0.4833 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1139 | 881 | | 6326 | 14317 | 189.9 | 47.31 | 165.02 | 129.26 | 138 | 151 | 161 | 171 | 182 | 193 | 206 | 224 | 252 | 0.0773 | 1106 | 1.024 | 100.80 | 38.29 | 1 | 0.0438 | 277 | 0.0012 | 42.09 | 7.012 | 0.1876 | 38280.7 | 8230000 | 1890000000 | 462000000000 | 0.4259 | 0.2291 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0057 | 0.0000 | 0.0234 | 0.0019 | 0.0776 | 0.0210 | 0.1558 | 0.0447 | 0.1631 | 0.0445 | 0.1831 | 0.0635 | 0.3895 | 0.8244 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0098 | 0.0003 | 0.0319 | 0.0121 | 0.0718 | 0.0241 | 0.0706 | 0.0168 | 0.0970 | 0.0254 | 0.7152 | 0.9213 | 0.0052 | 0.0064 | 0.0103 | 0.0107 | 0.0207 | 0.0258 | 0.0767 | 0.0794 | 0.1259 | 0.1803 | 0.1759 | 0.1674 | 0.1190 | 0.1180 | 0.1250 | 0.1545 | 0.3414 | 0.2575 | 0.0007 | 0.0055 | 0.0117 | 0.0371 | 0.0950 | 0.1273 | 0.1185 | 0.1383 | 0.4659 | 34 | 48 | 69 | 97 | 132 | 170 | 214 | 268 | 354 | 0.0028 | 59.79 | 6.896 | 0.2662 | 43937.1 | 15200000 | 6170000000 | 2820000000000 | 0.5199 | 0.1445 | 0.0243 | 0.0025 | 0.1004 | 0.0068 | 0.2160 | 0.0533 | 0.1831 | 0.1121 | 0.1711 | 0.1528 | 0.1263 | 0.1873 | 0.0814 | 0.1483 | 0.0675 | 0.1416 | 0.0300 | 0.1953 | 0.0008 | 0.0007 | 0.0008 | 0.0002 | 0.0040 | 0.0028 | 0.0205 | 0.0158 | 0.0656 | 0.0457 | 0.0960 | 0.0802 | 0.0795 | 0.0679 | 0.1224 | 0.0924 | 0.6103 | 0.6942 | 0.0013 | 0.0018 | 0.0055 | 0.0060 | 0.0103 | 0.0189 | 0.0352 | 0.0463 | 0.0967 | 0.1178 | 0.1415 | 0.1568 | 0.1118 | 0.1307 | 0.1417 | 0.1494 | 0.4561 | 0.3722 | 0.0007 | 0.0012 | 0.0066 | 0.0298 | 0.0752 | 0.1185 | 0.1015 | 0.1342 | 0.5323 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 968 | 293 | | 9056 | 13099 | 516.1 | 88.24 | 114.69 | 251.28 | 396 | 459 | 491 | 512 | 529 | 545 | 562 | 583 | 612 | 0.0837 | 1097 | 0.940 | 103.45 | 28.16 | 6 | 0.0282 | 255 | 0.0009 | 51.99 | 7.361 | 0.1986 | 274112.0 | 149000000 | 82200000000 | 46100000000000 | 0.4370 | 0.2059 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0050 | 0.0007 | 0.0278 | 0.0152 | 0.0543 | 0.0277 | 0.0482 | 0.0150 | 0.0760 | 0.0288 | 0.7879 | 0.9127 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0007 | 0.0168 | 0.0152 | 0.0317 | 0.0272 | 0.0203 | 0.0143 | 0.0351 | 0.0258 | 0.8942 | 0.9168 | 0.0106 | 0.0000 | 0.0080 | 0.0000 | 0.0359 | 0.0000 | 0.0638 | 0.0000 | 0.1237 | 0.0000 | 0.1463 | 0.0000 | 0.1077 | 0.0000 | 0.1303 | 0.0000 | 0.3737 | 0.0000 | 0.0015 | 0.0017 | 0.0063 | 0.0160 | 0.0428 | 0.0699 | 0.0713 | 0.1070 | 0.6836 | 8 | 10 | 12 | 14 | 20 | 34 | 63 | 120 | 305 | 0.0778 | 7.79 | 3.212 | 0.5546 | 76290.7 | 93700000 | 170000000000 | 429000000000000 | 0.7394 | 0.0357 | 0.0196 | 0.0006 | 0.0825 | 0.0106 | 0.1649 | 0.0417 | 0.1872 | 0.0636 | 0.1702 | 0.1514 | 0.1584 | 0.2125 | 0.1152 | 0.1383 | 0.0654 | 0.1383 | 0.0366 | 0.2430 | 0.0003 | 0.0000 | 0.0019 | 0.0013 | 0.0083 | 0.0037 | 0.0156 | 0.0088 | 0.0568 | 0.0470 | 0.0879 | 0.0948 | 0.0632 | 0.0564 | 0.0959 | 0.0866 | 0.6702 | 0.7013 | 0.0008 | 0.0005 | 0.0004 | 0.0014 | 0.0059 | 0.0028 | 0.0184 | 0.0229 | 0.0675 | 0.0744 | 0.1010 | 0.1155 | 0.0700 | 0.0734 | 0.1014 | 0.1001 | 0.6345 | 0.6090 | 0.0015 | 0.0018 | 0.0041 | 0.0170 | 0.0595 | 0.0983 | 0.0698 | 0.0953 | 0.6526 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 458 | 196 | | 2487 | 4852 | 502.4 | 108.13 | 28.97 | 67.04 | 323 | 396 | 462 | 498 | 525 | 549 | 572 | 595 | 625 | 0.1008 | 489 | 1.136 | 122.50 | 41.00 | 3 | 0.1186 | 295 | 0.0011 | 45.67 | 6.999 | 0.1815 | 264107.0 | 144000000 | 80400000000 | 45900000000000 | 0.4074 | 0.2236 | 0.0000 | 0.0000 | 0.0007 | 0.0017 | 0.0013 | 0.0017 | 0.0137 | 0.0038 | 0.0586 | 0.0196 | 0.1036 | 0.0325 | 0.0971 | 0.0282 | 0.1153 | 0.0440 | 0.6098 | 0.8684 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0017 | 0.0036 | 0.0038 | 0.0214 | 0.0196 | 0.0300 | 0.0311 | 0.0254 | 0.0230 | 0.0376 | 0.0358 | 0.8821 | 0.8834 | 0.0000 | 0.0000 | 0.0093 | 0.5000 | 0.0231 | 0.5000 | 0.0579 | 0.0000 | 0.1435 | 0.0000 | 0.2176 | 0.0000 | 0.0995 | 0.0000 | 0.1435 | 0.0000 | 0.3056 | 0.0000 | 0.0000 | 0.0021 | 0.0027 | 0.0103 | 0.0397 | 0.0637 | 0.0582 | 0.0794 | 0.7440 | 7 | 9 | 10 | 12 | 13 | 16 | 20 | 25 | 39 | 0.2290 | 1.64 | 2.351 | 0.8187 | 5332.5 | 2350000 | 1240000000 | 703000000000 | 0.6224 | 0.1004 | 0.0481 | 0.0325 | 0.0611 | 0.0293 | 0.0722 | 0.0357 | 0.0907 | 0.0325 | 0.1389 | 0.0523 | 0.1889 | 0.0722 | 0.1611 | 0.1094 | 0.1333 | 0.1665 | 0.1056 | 0.4695 | 0.0208 | 0.0226 | 0.0271 | 0.0203 | 0.0253 | 0.0231 | 0.0316 | 0.0220 | 0.0479 | 0.0365 | 0.0949 | 0.0602 | 0.0723 | 0.0747 | 0.1102 | 0.1169 | 0.5700 | 0.6238 | 0.0212 | 0.0086 | 0.0194 | 0.0107 | 0.0212 | 0.0086 | 0.0300 | 0.0193 | 0.0423 | 0.0428 | 0.0758 | 0.0600 | 0.0406 | 0.0450 | 0.0882 | 0.0878 | 0.6614 | 0.7173 | 0.0202 | 0.0265 | 0.0277 | 0.0429 | 0.0542 | 0.0845 | 0.0605 | 0.0782 | 0.6053 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 156 | 594 | | 9080 | 15618 | 311.0 | 68.29 | 98.46 | 121.64 | 229 | 251 | 270 | 288 | 305 | 324 | 344 | 367 | 401 | 0.0788 | 1231 | 0.960 | 135.72 | 35.01 | 1 | 0.0352 | 320 | 0.0013 | 28.86 | 6.929 | 0.2122 | 101409.0 | 34600000 | 12300000000 | 4590000000000 | 0.4537 | 0.2035 | 0.0010 | 0.0000 | 0.0019 | 0.0001 | 0.0068 | 0.0009 | 0.0222 | 0.0025 | 0.0705 | 0.0167 | 0.1362 | 0.0410 | 0.1452 | 0.0416 | 0.1613 | 0.0640 | 0.4548 | 0.8331 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0006 | 0.0099 | 0.0020 | 0.0293 | 0.0115 | 0.0662 | 0.0283 | 0.0633 | 0.0223 | 0.0823 | 0.0364 | 0.7452 | 0.8989 | 0.0056 | 0.0027 | 0.0124 | 0.0318 | 0.0204 | 0.0637 | 0.0667 | 0.1141 | 0.1248 | 0.2042 | 0.1513 | 0.1485 | 0.1328 | 0.0716 | 0.1575 | 0.1300 | 0.3286 | 0.2334 | 0.0007 | 0.0030 | 0.0096 | 0.0287 | 0.0674 | 0.1168 | 0.1070 | 0.1261 | 0.5408 | 12 | 14 | 17 | 23 | 41 | 74 | 118 | 173 | 260 | 0.0390 | 25.52 | 5.297 | 0.4490 | 24490.2 | 9030000 | 4150000000 | 2200000000000 | 0.5460 | 0.1292 | 0.0690 | 0.0018 | 0.1999 | 0.0187 | 0.2994 | 0.1257 | 0.1613 | 0.1617 | 0.1323 | 0.2185 | 0.0814 | 0.1892 | 0.0378 | 0.1186 | 0.0145 | 0.0981 | 0.0044 | 0.0678 | 0.0002 | 0.0003 | 0.0012 | 0.0006 | 0.0031 | 0.0027 | 0.0151 | 0.0124 | 0.0691 | 0.0593 | 0.1090 | 0.0934 | 0.0785 | 0.0690 | 0.1141 | 0.1000 | 0.6096 | 0.6622 | 0.0011 | 0.0015 | 0.0023 | 0.0025 | 0.0079 | 0.0093 | 0.0234 | 0.0284 | 0.0888 | 0.0944 | 0.1239 | 0.1444 | 0.0960 | 0.0946 | 0.1298 | 0.1284 | 0.5268 | 0.4966 | 0.0002 | 0.0022 | 0.0039 | 0.0202 | 0.0788 | 0.1208 | 0.0884 | 0.1238 | 0.5618 | ||
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 201 | 479 | | 6474 | 26300 | 321.0 | 57.21 | 100.08 | 124.51 | 249 | 270 | 287 | 303 | 318 | 334 | 351 | 372 | 398 | 0.0455 | 1196 | 1.134 | 99.86 | 37.59 | 2 | 0.0394 | 255 | 0.0006 | 73.06 | 7.553 | 0.1323 | 106297.0 | 36300000 | 12700000000 | 4580000000000 | 0.4555 | 0.1968 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0030 | 0.0002 | 0.0144 | 0.0008 | 0.0453 | 0.0123 | 0.1133 | 0.0261 | 0.1258 | 0.0247 | 0.1709 | 0.0467 | 0.5257 | 0.8892 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0002 | 0.0069 | 0.0003 | 0.0227 | 0.0113 | 0.0501 | 0.0206 | 0.0538 | 0.0157 | 0.0774 | 0.0244 | 0.7881 | 0.9275 | 0.0044 | 0.0805 | 0.0187 | 0.0575 | 0.0430 | 0.1839 | 0.0926 | 0.0920 | 0.1599 | 0.3103 | 0.1985 | 0.1379 | 0.1279 | 0.0460 | 0.1709 | 0.0805 | 0.1841 | 0.0115 | 0.0010 | 0.0025 | 0.0127 | 0.0290 | 0.0762 | 0.1275 | 0.1093 | 0.1393 | 0.5025 | 11 | 13 | 15 | 20 | 36 | 70 | 125 | 189 | 272 | 0.0574 | 15.56 | 4.832 | 0.5328 | 25517.2 | 9400000 | 4360000000 | 2400000000000 | 0.4719 | 0.1702 | 0.0761 | 0.0028 | 0.2702 | 0.0198 | 0.3311 | 0.1800 | 0.1322 | 0.2075 | 0.0992 | 0.2192 | 0.0530 | 0.1607 | 0.0236 | 0.0959 | 0.0105 | 0.0697 | 0.0042 | 0.0445 | 0.0001 | 0.0000 | 0.0007 | 0.0004 | 0.0009 | 0.0012 | 0.0101 | 0.0086 | 0.0551 | 0.0465 | 0.1067 | 0.0874 | 0.0756 | 0.0609 | 0.1039 | 0.0939 | 0.6470 | 0.7011 | 0.0004 | 0.0005 | 0.0005 | 0.0019 | 0.0037 | 0.0034 | 0.0152 | 0.0180 | 0.0736 | 0.0826 | 0.1416 | 0.1590 | 0.0968 | 0.1084 | 0.1346 | 0.1429 | 0.5337 | 0.4833 | 0.0006 | 0.0003 | 0.0023 | 0.0133 | 0.0603 | 0.1279 | 0.0841 | 0.1215 | 0.5898 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 949 | 628 | | 5444 | 5921 | 503.2 | 113.35 | 118.69 | 220.33 | 340 | 443 | 485 | 510 | 528 | 546 | 564 | 585 | 614 | 0.1099 | 651 | 1.294 | 20.22 | 8.60 | 1 | 0.0103 | 56 | 0.0029 | 17.80 | 6.312 | 0.3065 | 266047.0 | 145000000 | 80700000000 | 45600000000000 | 0.4084 | 0.2255 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0074 | 0.0008 | 0.0372 | 0.0133 | 0.0597 | 0.0230 | 0.0638 | 0.0153 | 0.1089 | 0.0266 | 0.7193 | 0.9208 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0004 | 0.0158 | 0.0130 | 0.0270 | 0.0200 | 0.0203 | 0.0120 | 0.0363 | 0.0200 | 0.8999 | 0.9346 | 0.0097 | 0.0000 | 0.0110 | 0.0789 | 0.0331 | 0.1579 | 0.0607 | 0.0789 | 0.1062 | 0.1842 | 0.1407 | 0.1053 | 0.1407 | 0.0789 | 0.1434 | 0.2105 | 0.3545 | 0.1053 | 0.0000 | 0.0009 | 0.0035 | 0.0087 | 0.0363 | 0.0603 | 0.0609 | 0.0873 | 0.7421 | 7 | 10 | 14 | 19 | 25 | 37 | 74 | 153 | 375 | 0.0775 | 22.34 | 4.056 | 0.5583 | 62626.7 | 51300000 | 50500000000 | 55700000000000 | 0.5274 | 0.1314 | 0.0603 | 0.0015 | 0.2190 | 0.0164 | 0.3175 | 0.0848 | 0.1429 | 0.1711 | 0.1524 | 0.2321 | 0.0603 | 0.2292 | 0.0222 | 0.1295 | 0.0159 | 0.0744 | 0.0095 | 0.0610 | 0.0013 | 0.0006 | 0.0051 | 0.0011 | 0.0019 | 0.0033 | 0.0103 | 0.0094 | 0.0994 | 0.0833 | 0.1186 | 0.1127 | 0.0962 | 0.0944 | 0.1237 | 0.1133 | 0.5436 | 0.5819 | 0.0000 | 0.0009 | 0.0016 | 0.0009 | 0.0072 | 0.0071 | 0.0177 | 0.0301 | 0.1157 | 0.1125 | 0.1301 | 0.1364 | 0.1028 | 0.0912 | 0.1205 | 0.1355 | 0.5044 | 0.4854 | 0.0007 | 0.0007 | 0.0036 | 0.0144 | 0.1114 | 0.1222 | 0.0978 | 0.1258 | 0.5234 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 791 | 738 | | 2836 | 2758 | 119.5 | 28.32 | 225.10 | 172.38 | 89 | 99 | 105 | 111 | 115 | 121 | 128 | 137 | 155 | 0.1653 | 456 | 0.603 | 236.69 | 51.26 | 1 | 0.2341 | 664 | 0.0036 | 15.13 | 5.972 | 0.2993 | 15085.0 | 2020000 | 291000000 | 45400000000 | 0.4422 | 0.2144 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0021 | 0.0000 | 0.0185 | 0.0042 | 0.0723 | 0.0261 | 0.1083 | 0.0465 | 0.1591 | 0.0519 | 0.1657 | 0.0711 | 0.4736 | 0.7998 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0067 | 0.0011 | 0.0387 | 0.0176 | 0.0627 | 0.0269 | 0.0753 | 0.0298 | 0.0867 | 0.0384 | 0.7285 | 0.8863 | 0.0070 | 0.0054 | 0.0234 | 0.0163 | 0.0422 | 0.0217 | 0.0749 | 0.0761 | 0.1218 | 0.1848 | 0.1124 | 0.1902 | 0.1101 | 0.1196 | 0.1077 | 0.1413 | 0.4005 | 0.2446 | 0.0041 | 0.0033 | 0.0231 | 0.0430 | 0.1017 | 0.1479 | 0.1083 | 0.1380 | 0.4306 | 20 | 53 | 93 | 143 | 203 | 256 | 310 | 368 | 462 | 0.0047 | 47.42 | 6.617 | 0.2813 | 80370.2 | 35100000 | 17400000000 | 9480000000000 | 0.5310 | 0.1251 | 0.0062 | 0.0011 | 0.1040 | 0.0067 | 0.1996 | 0.0540 | 0.2100 | 0.1012 | 0.1580 | 0.1609 | 0.1393 | 0.2014 | 0.1123 | 0.1620 | 0.0499 | 0.1215 | 0.0208 | 0.1912 | 0.0000 | 0.0000 | 0.0007 | 0.0012 | 0.0033 | 0.0024 | 0.0127 | 0.0135 | 0.0560 | 0.0483 | 0.1133 | 0.0889 | 0.0833 | 0.0700 | 0.1227 | 0.0948 | 0.6080 | 0.6810 | 0.0000 | 0.0025 | 0.0010 | 0.0074 | 0.0059 | 0.0086 | 0.0285 | 0.0395 | 0.1050 | 0.1210 | 0.1501 | 0.1444 | 0.0991 | 0.1222 | 0.1511 | 0.1543 | 0.4593 | 0.4000 | 0.0008 | 0.0008 | 0.0032 | 0.0244 | 0.0630 | 0.1198 | 0.1072 | 0.1308 | 0.5500 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 876 | | 4650 | 27974 | 298.2 | 83.39 | 212.92 | 186.19 | 196 | 225 | 246 | 269 | 291 | 315 | 341 | 374 | 413 | 0.0507 | 1418 | 1.135 | 46.75 | 17.00 | 6 | 0.0265 | 123 | 0.0006 | 64.25 | 7.641 | 0.1408 | 95900.4 | 32900000 | 11900000000 | 4530000000000 | 0.4875 | 0.1659 | 0.0004 | 0.0000 | 0.0022 | 0.0008 | 0.0057 | 0.0008 | 0.0284 | 0.0091 | 0.1091 | 0.0467 | 0.1916 | 0.0965 | 0.1414 | 0.0657 | 0.1689 | 0.1033 | 0.3522 | 0.6771 | 0.0000 | 0.0000 | 0.0009 | 0.0007 | 0.0020 | 0.0000 | 0.0128 | 0.0059 | 0.0483 | 0.0320 | 0.0762 | 0.0692 | 0.0556 | 0.0391 | 0.0829 | 0.0608 | 0.7213 | 0.7923 | 0.0017 | 0.0048 | 0.0035 | 0.0095 | 0.0096 | 0.0263 | 0.0192 | 0.0668 | 0.0925 | 0.1265 | 0.1187 | 0.1384 | 0.0855 | 0.1289 | 0.1309 | 0.1480 | 0.5384 | 0.3508 | 0.0014 | 0.0009 | 0.0059 | 0.0237 | 0.0702 | 0.0916 | 0.0766 | 0.0861 | 0.6436 | 27 | 52 | 83 | 117 | 157 | 208 | 270 | 356 | 482 | 0.0050 | 46.50 | 6.695 | 0.3231 | 79998.9 | 40100000 | 24000000000 | 16200000000000 | 0.4940 | 0.1623 | 0.0270 | 0.0010 | 0.1183 | 0.0111 | 0.2093 | 0.0488 | 0.1802 | 0.0945 | 0.1620 | 0.1643 | 0.1329 | 0.2010 | 0.0821 | 0.1517 | 0.0530 | 0.1382 | 0.0352 | 0.1895 | 0.0007 | 0.0001 | 0.0014 | 0.0010 | 0.0042 | 0.0026 | 0.0218 | 0.0137 | 0.0642 | 0.0508 | 0.1052 | 0.0828 | 0.0816 | 0.0668 | 0.1081 | 0.0927 | 0.6129 | 0.6894 | 0.0013 | 0.0016 | 0.0028 | 0.0069 | 0.0105 | 0.0144 | 0.0378 | 0.0507 | 0.0975 | 0.1038 | 0.1384 | 0.1575 | 0.1063 | 0.1060 | 0.1287 | 0.1379 | 0.4767 | 0.4212 | 0.0009 | 0.0024 | 0.0075 | 0.0292 | 0.0795 | 0.1238 | 0.0924 | 0.1217 | 0.5426 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 441 | 830 | | 4757 | 10543 | 286.6 | 105.44 | 372.79 | 417.10 | 125 | 169 | 222 | 270 | 315 | 343 | 363 | 383 | 408 | 0.0672 | 708 | 1.208 | 96.84 | 36.89 | 2 | 0.0526 | 250 | 0.0009 | 30.90 | 7.255 | 0.1963 | 93264.4 | 32700000 | 12000000000 | 4520000000000 | 0.3736 | 0.2485 | 0.0021 | 0.0000 | 0.0078 | 0.0000 | 0.0135 | 0.0025 | 0.0526 | 0.0072 | 0.1294 | 0.0416 | 0.1585 | 0.0782 | 0.1407 | 0.0682 | 0.1819 | 0.1216 | 0.3134 | 0.6807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0046 | 0.0019 | 0.0255 | 0.0172 | 0.0304 | 0.0316 | 0.0264 | 0.0207 | 0.0350 | 0.0340 | 0.8780 | 0.8947 | 0.0022 | 0.0105 | 0.0022 | 0.0122 | 0.0092 | 0.0385 | 0.0189 | 0.0769 | 0.0415 | 0.1486 | 0.0739 | 0.1766 | 0.0922 | 0.1276 | 0.1305 | 0.1678 | 0.6295 | 0.2413 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0260 | 0.0290 | 0.0297 | 0.0405 | 0.8684 | 20 | 29 | 48 | 102 | 197 | 329 | 504 | 714 | 1008 | 0.0138 | 104.97 | 6.639 | 0.3555 | 312926.0 | 340000000 | 425000000000 | 584000000000000 | 0.4678 | 0.1840 | 0.0316 | 0.0015 | 0.1275 | 0.0045 | 0.2614 | 0.0469 | 0.1743 | 0.0888 | 0.1536 | 0.1997 | 0.1373 | 0.2093 | 0.0632 | 0.1533 | 0.0316 | 0.1241 | 0.0196 | 0.1720 | 0.0000 | 0.0002 | 0.0009 | 0.0002 | 0.0020 | 0.0002 | 0.0098 | 0.0050 | 0.0431 | 0.0439 | 0.0803 | 0.0605 | 0.0592 | 0.0447 | 0.0801 | 0.0768 | 0.7247 | 0.7686 | 0.0003 | 0.0003 | 0.0006 | 0.0029 | 0.0026 | 0.0052 | 0.0149 | 0.0147 | 0.0584 | 0.0700 | 0.1094 | 0.1201 | 0.0788 | 0.0851 | 0.1186 | 0.1378 | 0.6164 | 0.5638 | 0.0000 | 0.0005 | 0.0018 | 0.0084 | 0.0562 | 0.0893 | 0.0659 | 0.1043 | 0.6735 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1203 | 196 | | 3608 | 1256 | 112.8 | 33.02 | 56.49 | 42.34 | 79 | 87 | 93 | 99 | 105 | 112 | 122 | 134 | 156 | 0.4076 | 512 | 0.975 | 95.35 | 33.06 | 2 | 0.0734 | 265 | 0.0032 | 16.99 | 6.143 | 0.2879 | 13822.0 | 1860000 | 276000000 | 45100000000 | 0.3979 | 0.2576 | 0.0010 | 0.0003 | 0.0065 | 0.0006 | 0.0176 | 0.0028 | 0.0391 | 0.0056 | 0.0918 | 0.0314 | 0.1565 | 0.0637 | 0.1590 | 0.0566 | 0.1951 | 0.0942 | 0.3335 | 0.7448 | 0.0004 | 0.0000 | 0.0026 | 0.0000 | 0.0097 | 0.0008 | 0.0164 | 0.0025 | 0.0421 | 0.0200 | 0.0742 | 0.0382 | 0.0753 | 0.0306 | 0.1037 | 0.0514 | 0.6755 | 0.8564 | 0.0102 | 0.0029 | 0.0116 | 0.0117 | 0.0277 | 0.0264 | 0.0524 | 0.0733 | 0.1252 | 0.1554 | 0.1514 | 0.1525 | 0.1208 | 0.1202 | 0.1339 | 0.1320 | 0.3668 | 0.3255 | 0.0035 | 0.0085 | 0.0148 | 0.0318 | 0.0890 | 0.1329 | 0.1025 | 0.1576 | 0.4594 | 20 | 26 | 31 | 37 | 45 | 55 | 65 | 79 | 102 | 0.0171 | 7.89 | 4.661 | 0.4707 | 4982.0 | 681992 | 133000000 | 33000000000 | 0.5597 | 0.0948 | 0.0435 | 0.0159 | 0.1268 | 0.0336 | 0.1739 | 0.0814 | 0.1775 | 0.1310 | 0.1920 | 0.1717 | 0.1522 | 0.1664 | 0.0942 | 0.1451 | 0.0254 | 0.1469 | 0.0145 | 0.1080 | 0.0016 | 0.0073 | 0.0126 | 0.0085 | 0.0316 | 0.0208 | 0.0411 | 0.0403 | 0.1785 | 0.1404 | 0.2054 | 0.2088 | 0.1627 | 0.1416 | 0.1769 | 0.1844 | 0.1896 | 0.2479 | 0.0056 | 0.0197 | 0.0364 | 0.0630 | 0.0756 | 0.0709 | 0.1064 | 0.1102 | 0.2269 | 0.2283 | 0.1961 | 0.1811 | 0.1064 | 0.1457 | 0.1457 | 0.1220 | 0.1008 | 0.0591 | 0.0021 | 0.0123 | 0.0452 | 0.0903 | 0.2074 | 0.2177 | 0.1561 | 0.1335 | 0.1355 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1130 | 460 | | 653 | 578 | 83.3 | 9.22 | 65.56 | 101.38 | 71 | 74 | 78 | 80 | 83 | 86 | 89 | 92 | 95 | 0.3910 | 226 | 0.478 | 77.79 | 11.31 | 1 | 0.3155 | 206 | 0.1159 | 0.55 | 2.394 | 0.7678 | 7017.7 | 598559 | 51600000 | 4510000000 | 0.4222 | 0.2132 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0065 | 0.0015 | 0.0455 | 0.0352 | 0.0698 | 0.0674 | 0.0779 | 0.0260 | 0.1347 | 0.0475 | 0.6623 | 0.8224 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0047 | 0.0015 | 0.0376 | 0.0352 | 0.0610 | 0.0674 | 0.0297 | 0.0260 | 0.0563 | 0.0475 | 0.8075 | 0.8224 | 0.1304 | 0.0000 | 0.3478 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0435 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0151 | 0.0211 | 0.0452 | 0.0994 | 0.0964 | 0.1325 | 0.1687 | 0.4187 | 7 | 10 | 13 | 18 | 24 | 35 | 52 | 90 | 200 | 0.0809 | 31.27 | 3.431 | 0.5091 | 14559.2 | 5410000 | 2520000000 | 1320000000000 | 0.5610 | 0.0846 | 0.2727 | 0.0094 | 0.5000 | 0.0377 | 0.2273 | 0.4151 | 0.0000 | 0.3396 | 0.0000 | 0.1038 | 0.0000 | 0.0849 | 0.0000 | 0.0094 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0405 | 0.0091 | 0.0173 | 0.0274 | 0.0347 | 0.0365 | 0.2023 | 0.1507 | 0.3410 | 0.3196 | 0.1676 | 0.1553 | 0.1850 | 0.1918 | 0.0116 | 0.1050 | 0.0155 | 0.0177 | 0.0233 | 0.0265 | 0.0698 | 0.0885 | 0.0853 | 0.0619 | 0.2636 | 0.3894 | 0.3488 | 0.3009 | 0.1860 | 0.1150 | 0.0078 | 0.0000 | 0.0000 | 0.0000 | 0.0134 | 0.0201 | 0.0336 | 0.0336 | 0.2282 | 0.3758 | 0.2013 | 0.0940 | 0.0000 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 615 | 87 | | 3644 | 13644 | 486.1 | 117.15 | 117.91 | 188.35 | 319 | 379 | 428 | 463 | 490 | 516 | 545 | 579 | 629 | 0.0704 | 960 | 0.778 | 78.75 | 25.08 | 2 | 0.0645 | 235 | 0.0008 | 59.20 | 7.366 | 0.1629 | 250045.0 | 135000000 | 76400000000 | 45000000000000 | 0.3808 | 0.2634 | 0.0005 | 0.0003 | 0.0023 | 0.0006 | 0.0065 | 0.0012 | 0.0208 | 0.0024 | 0.0644 | 0.0260 | 0.1185 | 0.0474 | 0.1181 | 0.0477 | 0.1537 | 0.0608 | 0.5153 | 0.8136 | 0.0004 | 0.0003 | 0.0004 | 0.0006 | 0.0025 | 0.0009 | 0.0053 | 0.0017 | 0.0246 | 0.0206 | 0.0421 | 0.0342 | 0.0333 | 0.0284 | 0.0512 | 0.0353 | 0.8404 | 0.8781 | 0.0029 | 0.0165 | 0.0072 | 0.0110 | 0.0435 | 0.0165 | 0.0609 | 0.0824 | 0.1493 | 0.1319 | 0.1493 | 0.1648 | 0.1232 | 0.1044 | 0.1130 | 0.1154 | 0.3507 | 0.3571 | 0.0011 | 0.0005 | 0.0037 | 0.0186 | 0.0541 | 0.0981 | 0.1140 | 0.1352 | 0.5748 | 5 | 7 | 9 | 12 | 18 | 41 | 105 | 209 | 414 | 0.0925 | 12.28 | 4.224 | 0.5614 | 49376.8 | 28700000 | 20000000000 | 16200000000000 | 0.4378 | 0.2206 | 0.0432 | 0.0012 | 0.1512 | 0.0148 | 0.2160 | 0.0598 | 0.1677 | 0.1006 | 0.1423 | 0.1764 | 0.1017 | 0.1795 | 0.0839 | 0.1388 | 0.0597 | 0.1184 | 0.0343 | 0.2104 | 0.0002 | 0.0000 | 0.0007 | 0.0011 | 0.0035 | 0.0013 | 0.0091 | 0.0065 | 0.0424 | 0.0378 | 0.0666 | 0.0551 | 0.0544 | 0.0477 | 0.0811 | 0.0656 | 0.7419 | 0.7849 | 0.0006 | 0.0006 | 0.0023 | 0.0029 | 0.0046 | 0.0048 | 0.0126 | 0.0140 | 0.0584 | 0.0619 | 0.0822 | 0.0909 | 0.0664 | 0.0635 | 0.0908 | 0.0804 | 0.6821 | 0.6810 | 0.0000 | 0.0018 | 0.0028 | 0.0106 | 0.0536 | 0.0732 | 0.0590 | 0.0912 | 0.7077 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 518 | 503 | | 15648 | 56021 | 320.9 | 59.50 | 142.33 | 181.99 | 244 | 279 | 299 | 315 | 329 | 341 | 354 | 368 | 389 | 0.0239 | 1341 | 0.987 | 126.85 | 36.01 | 1 | 0.0202 | 316 | 0.0015 | 21.65 | 6.855 | 0.2488 | 106538.0 | 36300000 | 12600000000 | 4480000000000 | 0.4413 | 0.2040 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0079 | 0.0003 | 0.0295 | 0.0078 | 0.0562 | 0.0157 | 0.0615 | 0.0104 | 0.0915 | 0.0162 | 0.7503 | 0.9496 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0109 | 0.0075 | 0.0242 | 0.0143 | 0.0210 | 0.0081 | 0.0316 | 0.0119 | 0.9098 | 0.9580 | 0.0090 | 0.0536 | 0.0157 | 0.0179 | 0.0336 | 0.1429 | 0.0745 | 0.2143 | 0.1272 | 0.1429 | 0.1557 | 0.1607 | 0.1429 | 0.1071 | 0.1597 | 0.0357 | 0.2818 | 0.1250 | 0.0008 | 0.0025 | 0.0050 | 0.0158 | 0.0410 | 0.0684 | 0.0815 | 0.0977 | 0.6873 | 8 | 10 | 12 | 18 | 51 | 108 | 178 | 269 | 424 | 0.1076 | 16.66 | 4.969 | 0.5393 | 53375.8 | 26600000 | 15300000000 | 9680000000000 | 0.3694 | 0.2725 | 0.0166 | 0.0013 | 0.1012 | 0.0060 | 0.2168 | 0.0361 | 0.1910 | 0.0912 | 0.1770 | 0.1724 | 0.1403 | 0.2115 | 0.0824 | 0.1547 | 0.0457 | 0.1475 | 0.0291 | 0.1792 | 0.0006 | 0.0002 | 0.0006 | 0.0006 | 0.0027 | 0.0015 | 0.0085 | 0.0065 | 0.0354 | 0.0299 | 0.0682 | 0.0565 | 0.0555 | 0.0459 | 0.0719 | 0.0641 | 0.7567 | 0.7947 | 0.0005 | 0.0005 | 0.0022 | 0.0022 | 0.0040 | 0.0048 | 0.0126 | 0.0154 | 0.0463 | 0.0551 | 0.0837 | 0.0934 | 0.0695 | 0.0743 | 0.0862 | 0.0911 | 0.6950 | 0.6633 | 0.0005 | 0.0017 | 0.0041 | 0.0114 | 0.0416 | 0.0737 | 0.0613 | 0.0797 | 0.7260 |