High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1111 | 520 | | 5855 | 6285 | 143.7 | 37.71 | 129.84 | 96.11 | 100 | 111 | 121 | 130 | 139 | 148 | 159 | 173 | 193 | 0.1158 | 728 | 1.106 | 84.72 | 30.89 | 1 | 0.0386 | 226 | 0.0018 | 22.88 | 6.593 | 0.2522 | 22082.0 | 3630000 | 639000000 | 120000000000 | 0.4079 | 0.2384 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0053 | 0.0009 | 0.0273 | 0.0032 | 0.0825 | 0.0265 | 0.1384 | 0.0467 | 0.1437 | 0.0495 | 0.1713 | 0.0767 | 0.4291 | 0.7964 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0007 | 0.0111 | 0.0024 | 0.0330 | 0.0159 | 0.0489 | 0.0238 | 0.0561 | 0.0196 | 0.0820 | 0.0283 | 0.7655 | 0.9092 | 0.0051 | 0.0118 | 0.0093 | 0.0212 | 0.0144 | 0.0259 | 0.0433 | 0.1108 | 0.1155 | 0.1769 | 0.1606 | 0.1792 | 0.1189 | 0.1321 | 0.1589 | 0.1179 | 0.3738 | 0.2241 | 0.0000 | 0.0026 | 0.0098 | 0.0298 | 0.0706 | 0.1009 | 0.1024 | 0.1220 | 0.5618 | 32 | 50 | 66 | 81 | 103 | 128 | 163 | 209 | 265 | 0.0036 | 23.50 | 6.280 | 0.3297 | 26095.3 | 6930000 | 2240000000 | 849000000000 | 0.5029 | 0.1525 | 0.0154 | 0.0026 | 0.0867 | 0.0100 | 0.1762 | 0.0374 | 0.1734 | 0.0756 | 0.1861 | 0.1538 | 0.1463 | 0.2112 | 0.0976 | 0.1556 | 0.0623 | 0.1460 | 0.0560 | 0.2077 | 0.0013 | 0.0013 | 0.0035 | 0.0021 | 0.0061 | 0.0080 | 0.0218 | 0.0157 | 0.0609 | 0.0519 | 0.0984 | 0.0855 | 0.0853 | 0.0703 | 0.1093 | 0.0883 | 0.6133 | 0.6770 | 0.0010 | 0.0013 | 0.0030 | 0.0088 | 0.0075 | 0.0157 | 0.0293 | 0.0452 | 0.0974 | 0.1129 | 0.1546 | 0.1763 | 0.1133 | 0.1129 | 0.1362 | 0.1412 | 0.4578 | 0.3858 | 0.0004 | 0.0036 | 0.0101 | 0.0222 | 0.0677 | 0.1431 | 0.0879 | 0.1278 | 0.5371 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1163 | 914 | | 2848 | 4080 | 128.2 | 26.29 | 72.09 | 52.48 | 98 | 106 | 112 | 118 | 124 | 131 | 140 | 151 | 166 | 0.1199 | 489 | 1.053 | 105.55 | 34.18 | 1 | 0.0952 | 271 | 0.0016 | 34.35 | 6.710 | 0.2008 | 17134.3 | 2390000 | 346000000 | 52000000000 | 0.4596 | 0.1985 | 0.0005 | 0.0000 | 0.0026 | 0.0000 | 0.0083 | 0.0011 | 0.0365 | 0.0033 | 0.0813 | 0.0228 | 0.1370 | 0.0538 | 0.1370 | 0.0435 | 0.1917 | 0.0748 | 0.4052 | 0.8007 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0021 | 0.0004 | 0.0153 | 0.0004 | 0.0425 | 0.0148 | 0.0689 | 0.0445 | 0.0669 | 0.0169 | 0.1102 | 0.0342 | 0.6929 | 0.8889 | 0.0060 | 0.0252 | 0.0099 | 0.0672 | 0.0298 | 0.0756 | 0.0736 | 0.2521 | 0.1650 | 0.2017 | 0.2107 | 0.1513 | 0.1233 | 0.0924 | 0.1551 | 0.1008 | 0.2266 | 0.0336 | 0.0031 | 0.0039 | 0.0164 | 0.0374 | 0.0997 | 0.1394 | 0.1012 | 0.1355 | 0.4634 | 25 | 34 | 43 | 51 | 59 | 69 | 81 | 99 | 131 | 0.0231 | 3.25 | 4.328 | 0.5781 | 7950.5 | 1300000 | 290000000 | 79400000000 | 0.5593 | 0.1262 | 0.0086 | 0.0015 | 0.0574 | 0.0068 | 0.1463 | 0.0181 | 0.1663 | 0.0556 | 0.1740 | 0.1171 | 0.1463 | 0.1679 | 0.1205 | 0.1445 | 0.1052 | 0.1723 | 0.0755 | 0.3163 | 0.0019 | 0.0011 | 0.0057 | 0.0032 | 0.0127 | 0.0081 | 0.0340 | 0.0218 | 0.0816 | 0.0567 | 0.1108 | 0.0820 | 0.1066 | 0.0753 | 0.1472 | 0.1137 | 0.4995 | 0.6383 | 0.0028 | 0.0063 | 0.0084 | 0.0063 | 0.0307 | 0.0378 | 0.0568 | 0.0908 | 0.1331 | 0.1311 | 0.1695 | 0.1702 | 0.1089 | 0.1059 | 0.1406 | 0.1248 | 0.3492 | 0.3266 | 0.0071 | 0.0065 | 0.0162 | 0.0518 | 0.0945 | 0.1579 | 0.1204 | 0.1379 | 0.4078 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 129 | 102 | | 853 | 4631 | 107.8 | 32.30 | 12.53 | 4.15 | 72 | 80 | 87 | 94 | 102 | 110 | 119 | 135 | 159 | 0.1162 | 538 | 1.081 | 46.87 | 17.49 | 1 | 0.1489 | 127 | 0.0142 | 2.79 | 4.517 | 0.4969 | 12655.4 | 1610000 | 221000000 | 32300000000 | 0.4358 | 0.2021 | 0.0024 | 0.0000 | 0.0024 | 0.0028 | 0.0097 | 0.0014 | 0.0607 | 0.0185 | 0.1602 | 0.0541 | 0.1990 | 0.1223 | 0.1553 | 0.0896 | 0.1456 | 0.1181 | 0.2646 | 0.5932 | 0.0017 | 0.0000 | 0.0017 | 0.0012 | 0.0066 | 0.0000 | 0.0249 | 0.0111 | 0.0731 | 0.0382 | 0.0897 | 0.0764 | 0.0797 | 0.0480 | 0.1030 | 0.0640 | 0.6196 | 0.7611 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0105 | 0.0092 | 0.0316 | 0.0734 | 0.0947 | 0.1376 | 0.1211 | 0.1835 | 0.0789 | 0.1193 | 0.1421 | 0.1835 | 0.5105 | 0.2936 | 0.0055 | 0.0055 | 0.0110 | 0.0440 | 0.0769 | 0.1044 | 0.1181 | 0.1209 | 0.5137 | 7 | 9 | 10 | 11 | 12 | 13 | 14 | 16 | 18 | 0.0078 | 26.38 | 5.307 | 0.2385 | 174.1 | 2649.31 | 43748.6 | 779909 | 0.5184 | 0.1395 | 0.0240 | 0.0003 | 0.0831 | 0.0035 | 0.1717 | 0.0122 | 0.2432 | 0.0319 | 0.2538 | 0.0856 | 0.1461 | 0.1297 | 0.0621 | 0.2158 | 0.0130 | 0.3053 | 0.0030 | 0.2158 | 0.0040 | 0.0000 | 0.0242 | 0.0010 | 0.0646 | 0.0043 | 0.1036 | 0.0183 | 0.1480 | 0.0550 | 0.1705 | 0.0815 | 0.1609 | 0.1399 | 0.1487 | 0.2628 | 0.1755 | 0.4372 | 0.1595 | 0.2552 | 0.1673 | 0.1849 | 0.1399 | 0.1094 | 0.1145 | 0.1484 | 0.1243 | 0.1198 | 0.0920 | 0.0964 | 0.0841 | 0.0495 | 0.0626 | 0.0339 | 0.0558 | 0.0026 | 0.0301 | 0.0872 | 0.1248 | 0.1442 | 0.1442 | 0.1368 | 0.1113 | 0.1076 | 0.1136 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1152 | 223 | | 1691 | 12352 | 99.2 | 17.11 | 46.92 | 69.30 | 79 | 84 | 88 | 92 | 96 | 101 | 107 | 114 | 124 | 0.0508 | 627 | 1.190 | 91.98 | 34.23 | 1 | 0.1366 | 231 | 0.0065 | 7.72 | 5.324 | 0.3702 | 10134.8 | 1070000 | 116000000 | 12900000000 | 0.3875 | 0.2575 | 0.0008 | 0.0000 | 0.0040 | 0.0000 | 0.0127 | 0.0000 | 0.0343 | 0.0024 | 0.0741 | 0.0253 | 0.1076 | 0.0519 | 0.1139 | 0.0404 | 0.1777 | 0.0821 | 0.4749 | 0.7978 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0047 | 0.0000 | 0.0206 | 0.0018 | 0.0419 | 0.0231 | 0.0599 | 0.0420 | 0.0573 | 0.0213 | 0.0879 | 0.0390 | 0.7264 | 0.8729 | 0.0121 | 0.1176 | 0.0040 | 0.1765 | 0.0526 | 0.2353 | 0.0931 | 0.2941 | 0.1336 | 0.1176 | 0.1903 | 0.0588 | 0.1579 | 0.0000 | 0.1741 | 0.0000 | 0.1822 | 0.0000 | 0.0039 | 0.0065 | 0.0310 | 0.0233 | 0.0802 | 0.1125 | 0.1035 | 0.1475 | 0.4916 | 7 | 10 | 13 | 17 | 23 | 32 | 44 | 64 | 112 | 0.0318 | 9.40 | 4.580 | 0.5581 | 7003.8 | 2350000 | 1290000000 | 919000000000 | 0.6011 | 0.1309 | 0.0239 | 0.0061 | 0.0710 | 0.0163 | 0.1253 | 0.0476 | 0.1857 | 0.0850 | 0.1744 | 0.1282 | 0.1459 | 0.1473 | 0.1187 | 0.1486 | 0.1054 | 0.1514 | 0.0497 | 0.2694 | 0.0028 | 0.0028 | 0.0058 | 0.0052 | 0.0106 | 0.0099 | 0.0311 | 0.0268 | 0.0659 | 0.0579 | 0.0954 | 0.0806 | 0.0809 | 0.0798 | 0.1143 | 0.1059 | 0.5934 | 0.6311 | 0.0056 | 0.0063 | 0.0141 | 0.0117 | 0.0159 | 0.0184 | 0.0286 | 0.0284 | 0.0766 | 0.0755 | 0.1048 | 0.1172 | 0.0886 | 0.0893 | 0.1172 | 0.1247 | 0.5485 | 0.5286 | 0.0026 | 0.0105 | 0.0228 | 0.0324 | 0.0762 | 0.0964 | 0.0836 | 0.1155 | 0.5599 | ||
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 425 | | 3025 | 6544 | 395.4 | 125.68 | 137.78 | 188.28 | 223 | 262 | 321 | 379 | 427 | 461 | 488 | 513 | 538 | 0.0767 | 502 | 0.961 | 105.32 | 29.00 | 2 | 0.0826 | 250 | 0.0010 | 36.99 | 7.117 | 0.2145 | 172122.0 | 79400000 | 38000000000 | 18700000000000 | 0.3829 | 0.2510 | 0.0000 | 0.0004 | 0.0066 | 0.0000 | 0.0094 | 0.0020 | 0.0169 | 0.0065 | 0.0778 | 0.0296 | 0.1321 | 0.0455 | 0.0965 | 0.0386 | 0.1781 | 0.0771 | 0.4827 | 0.8002 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0008 | 0.0014 | 0.0034 | 0.0182 | 0.0191 | 0.0383 | 0.0309 | 0.0163 | 0.0202 | 0.0299 | 0.0313 | 0.8954 | 0.8944 | 0.0019 | 0.0438 | 0.0028 | 0.0500 | 0.0112 | 0.0813 | 0.0168 | 0.0625 | 0.0493 | 0.1125 | 0.0503 | 0.1250 | 0.0615 | 0.1438 | 0.0829 | 0.1250 | 0.7235 | 0.2563 | 0.0000 | 0.0000 | 0.0012 | 0.0058 | 0.0226 | 0.0423 | 0.0359 | 0.0469 | 0.8454 | 11 | 15 | 21 | 35 | 61 | 94 | 140 | 217 | 376 | 0.0253 | 45.28 | 5.475 | 0.4795 | 54428.7 | 33000000 | 24600000000 | 20600000000000 | 0.5487 | 0.1238 | 0.0167 | 0.0007 | 0.0866 | 0.0051 | 0.1596 | 0.0425 | 0.1368 | 0.0717 | 0.1733 | 0.1281 | 0.1459 | 0.1801 | 0.1277 | 0.1274 | 0.0745 | 0.1384 | 0.0790 | 0.3060 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0017 | 0.0014 | 0.0118 | 0.0099 | 0.0557 | 0.0437 | 0.0861 | 0.0757 | 0.0621 | 0.0493 | 0.0807 | 0.0746 | 0.7002 | 0.7454 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0082 | 0.0068 | 0.0211 | 0.0271 | 0.0637 | 0.0780 | 0.1129 | 0.1248 | 0.0825 | 0.0753 | 0.0953 | 0.1031 | 0.6152 | 0.5848 | 0.0000 | 0.0010 | 0.0035 | 0.0129 | 0.0662 | 0.1005 | 0.0672 | 0.0985 | 0.6502 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1097 | 401 | | 5619 | 10511 | 100.4 | 25.69 | 150.94 | 167.26 | 71 | 79 | 86 | 92 | 97 | 103 | 110 | 119 | 132 | 0.0786 | 826 | 0.983 | 96.05 | 27.31 | 1 | 0.0418 | 235 | 0.0033 | 15.27 | 6.069 | 0.2967 | 10734.1 | 1230000 | 151000000 | 19900000000 | 0.4514 | 0.2026 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0093 | 0.0000 | 0.0335 | 0.0025 | 0.0924 | 0.0231 | 0.1475 | 0.0450 | 0.1673 | 0.0550 | 0.1991 | 0.0865 | 0.3487 | 0.7879 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0000 | 0.0089 | 0.0002 | 0.0392 | 0.0149 | 0.0643 | 0.0223 | 0.0770 | 0.0225 | 0.1061 | 0.0415 | 0.7020 | 0.8987 | 0.0103 | 0.0074 | 0.0197 | 0.0245 | 0.0310 | 0.0515 | 0.0874 | 0.0711 | 0.1400 | 0.1985 | 0.1805 | 0.1642 | 0.1184 | 0.1201 | 0.1391 | 0.1569 | 0.2735 | 0.2059 | 0.0012 | 0.0051 | 0.0125 | 0.0446 | 0.0896 | 0.1405 | 0.1151 | 0.1526 | 0.4387 | 11 | 17 | 32 | 53 | 79 | 117 | 181 | 290 | 415 | 0.0097 | 71.41 | 6.470 | 0.3608 | 50757.6 | 22700000 | 11700000000 | 6580000000000 | 0.5255 | 0.1681 | 0.0205 | 0.0024 | 0.1212 | 0.0122 | 0.2269 | 0.0538 | 0.1561 | 0.1204 | 0.1448 | 0.1703 | 0.1458 | 0.1689 | 0.0791 | 0.1385 | 0.0565 | 0.1434 | 0.0493 | 0.1899 | 0.0005 | 0.0004 | 0.0015 | 0.0008 | 0.0056 | 0.0018 | 0.0121 | 0.0135 | 0.0522 | 0.0488 | 0.0869 | 0.0725 | 0.0689 | 0.0674 | 0.0959 | 0.0926 | 0.6765 | 0.7021 | 0.0000 | 0.0007 | 0.0022 | 0.0011 | 0.0060 | 0.0049 | 0.0133 | 0.0226 | 0.0616 | 0.0560 | 0.1042 | 0.1173 | 0.0801 | 0.0920 | 0.1087 | 0.1117 | 0.6238 | 0.5937 | 0.0014 | 0.0025 | 0.0061 | 0.0150 | 0.0574 | 0.0872 | 0.0738 | 0.0955 | 0.6611 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 916 | 643 | | 6177 | 7967 | 199.4 | 44.34 | 175.07 | 133.71 | 150 | 163 | 173 | 182 | 192 | 203 | 216 | 234 | 259 | 0.0964 | 768 | 0.994 | 106.57 | 33.42 | 1 | 0.0440 | 272 | 0.0013 | 36.60 | 6.944 | 0.1957 | 41711.5 | 9180000 | 2130000000 | 520000000000 | 0.4243 | 0.2275 | 0.0010 | 0.0000 | 0.0007 | 0.0000 | 0.0032 | 0.0000 | 0.0168 | 0.0009 | 0.0753 | 0.0176 | 0.1308 | 0.0425 | 0.1402 | 0.0375 | 0.1836 | 0.0678 | 0.4482 | 0.8336 | 0.0006 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0000 | 0.0076 | 0.0005 | 0.0326 | 0.0112 | 0.0591 | 0.0230 | 0.0595 | 0.0150 | 0.0870 | 0.0231 | 0.7518 | 0.9272 | 0.0009 | 0.0179 | 0.0091 | 0.0358 | 0.0174 | 0.0657 | 0.0659 | 0.1343 | 0.1473 | 0.1433 | 0.1738 | 0.1791 | 0.1363 | 0.0955 | 0.1537 | 0.1164 | 0.2955 | 0.2119 | 0.0011 | 0.0033 | 0.0110 | 0.0375 | 0.0824 | 0.1191 | 0.1085 | 0.1393 | 0.4978 | 30 | 56 | 84 | 112 | 145 | 182 | 223 | 277 | 360 | 0.0025 | 69.87 | 6.927 | 0.2586 | 48522.6 | 17600000 | 7750000000 | 3970000000000 | 0.4873 | 0.1778 | 0.0220 | 0.0017 | 0.1111 | 0.0031 | 0.1870 | 0.0584 | 0.1544 | 0.1117 | 0.1816 | 0.1633 | 0.1457 | 0.1879 | 0.0951 | 0.1507 | 0.0552 | 0.1240 | 0.0479 | 0.1992 | 0.0002 | 0.0004 | 0.0014 | 0.0006 | 0.0029 | 0.0018 | 0.0145 | 0.0127 | 0.0737 | 0.0543 | 0.1090 | 0.0980 | 0.0872 | 0.0692 | 0.1206 | 0.1000 | 0.5904 | 0.6629 | 0.0015 | 0.0034 | 0.0019 | 0.0029 | 0.0087 | 0.0147 | 0.0417 | 0.0563 | 0.1059 | 0.1337 | 0.1647 | 0.1768 | 0.1097 | 0.1254 | 0.1514 | 0.1528 | 0.4144 | 0.3340 | 0.0006 | 0.0033 | 0.0072 | 0.0275 | 0.0899 | 0.1341 | 0.1039 | 0.1338 | 0.4997 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 372 | 900 | | 5044 | 9324 | 570.5 | 98.09 | 110.30 | 193.81 | 423 | 504 | 548 | 574 | 591 | 608 | 625 | 644 | 675 | 0.0741 | 691 | 0.949 | 144.16 | 41.87 | 3 | 0.0765 | 386 | 0.0009 | 58.08 | 7.313 | 0.1858 | 335121.0 | 201000000 | 123000000000 | 76200000000000 | 0.4530 | 0.1918 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0002 | 0.0055 | 0.0012 | 0.0271 | 0.0139 | 0.0472 | 0.0212 | 0.0462 | 0.0133 | 0.0650 | 0.0234 | 0.8066 | 0.9268 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0018 | 0.0012 | 0.0148 | 0.0139 | 0.0237 | 0.0212 | 0.0189 | 0.0133 | 0.0283 | 0.0218 | 0.9121 | 0.9285 | 0.0051 | 1.0000 | 0.0204 | 0.0000 | 0.0382 | 0.0000 | 0.0789 | 0.0000 | 0.1399 | 0.0000 | 0.1527 | 0.0000 | 0.1425 | 0.0000 | 0.1552 | 0.0000 | 0.2672 | 0.0000 | 0.0006 | 0.0016 | 0.0039 | 0.0132 | 0.0319 | 0.0631 | 0.0673 | 0.0879 | 0.7304 | 13 | 15 | 17 | 20 | 24 | 37 | 65 | 143 | 347 | 0.2499 | 4.68 | 3.068 | 0.7533 | 49725.0 | 35000000 | 30000000000 | 29200000000000 | 0.6863 | 0.0611 | 0.0201 | 0.0070 | 0.0828 | 0.0120 | 0.2081 | 0.0468 | 0.1834 | 0.0807 | 0.1969 | 0.1723 | 0.1454 | 0.1912 | 0.0805 | 0.1524 | 0.0403 | 0.1404 | 0.0425 | 0.1972 | 0.0004 | 0.0022 | 0.0004 | 0.0022 | 0.0021 | 0.0065 | 0.0116 | 0.0151 | 0.0418 | 0.0391 | 0.0708 | 0.0613 | 0.0472 | 0.0459 | 0.0911 | 0.0911 | 0.7345 | 0.7368 | 0.0000 | 0.0006 | 0.0005 | 0.0006 | 0.0051 | 0.0011 | 0.0142 | 0.0146 | 0.0524 | 0.0611 | 0.0956 | 0.0952 | 0.0478 | 0.0538 | 0.0935 | 0.0947 | 0.6909 | 0.6784 | 0.0000 | 0.0000 | 0.0019 | 0.0116 | 0.0551 | 0.0811 | 0.0487 | 0.0982 | 0.7034 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 580 | 433 | | 1493 | 7000 | 280.3 | 39.92 | 26.94 | 45.70 | 230 | 246 | 259 | 269 | 278 | 289 | 298 | 312 | 333 | 0.0730 | 511 | 0.722 | 72.57 | 16.03 | 1 | 0.1092 | 163 | 0.0044 | 8.62 | 5.687 | 0.3499 | 80150.8 | 23400000 | 6950000000 | 2110000000000 | 0.4223 | 0.2148 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0007 | 0.0385 | 0.0235 | 0.0577 | 0.0450 | 0.0513 | 0.0215 | 0.0810 | 0.0403 | 0.7642 | 0.8690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0007 | 0.0246 | 0.0221 | 0.0377 | 0.0442 | 0.0261 | 0.0181 | 0.0399 | 0.0328 | 0.8681 | 0.8821 | 0.0226 | 0.2000 | 0.0150 | 0.2000 | 0.0526 | 0.4000 | 0.0677 | 0.2000 | 0.0602 | 0.0000 | 0.1053 | 0.0000 | 0.0902 | 0.0000 | 0.1278 | 0.0000 | 0.4586 | 0.0000 | 0.0014 | 0.0014 | 0.0069 | 0.0220 | 0.0495 | 0.0755 | 0.0975 | 0.1319 | 0.6140 | 7 | 8 | 9 | 10 | 12 | 15 | 20 | 33 | 57 | 0.2933 | 1.67 | 2.358 | 0.8342 | 2814.2 | 777978 | 343000000 | 188000000000 | 0.6091 | 0.1098 | 0.0437 | 0.0353 | 0.0542 | 0.0453 | 0.0822 | 0.0637 | 0.1014 | 0.0599 | 0.1294 | 0.0860 | 0.1451 | 0.1083 | 0.1521 | 0.1045 | 0.1573 | 0.1421 | 0.1346 | 0.3548 | 0.0065 | 0.0172 | 0.0101 | 0.0192 | 0.0081 | 0.0204 | 0.0141 | 0.0188 | 0.0252 | 0.0337 | 0.0348 | 0.0425 | 0.0403 | 0.0357 | 0.0685 | 0.0665 | 0.7924 | 0.7459 | 0.0035 | 0.0050 | 0.0042 | 0.0084 | 0.0099 | 0.0168 | 0.0156 | 0.0218 | 0.0453 | 0.0536 | 0.0545 | 0.0662 | 0.0630 | 0.0679 | 0.1288 | 0.1274 | 0.6752 | 0.6329 | 0.0024 | 0.0047 | 0.0082 | 0.0141 | 0.0294 | 0.0500 | 0.0488 | 0.1106 | 0.7318 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1103 | 517 | | 8577 | 27567 | 251.0 | 73.86 | 67.12 | 106.49 | 158 | 187 | 212 | 231 | 249 | 269 | 291 | 317 | 347 | 0.0463 | 1277 | 0.999 | 61.74 | 14.87 | 3 | 0.0160 | 137 | 0.0006 | 49.24 | 7.634 | 0.1718 | 68432.9 | 19900000 | 6110000000 | 1960000000000 | 0.3917 | 0.2259 | 0.0010 | 0.0000 | 0.0014 | 0.0003 | 0.0060 | 0.0008 | 0.0247 | 0.0042 | 0.0651 | 0.0238 | 0.1257 | 0.0510 | 0.1228 | 0.0509 | 0.1551 | 0.0690 | 0.4982 | 0.8000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0003 | 0.0051 | 0.0018 | 0.0196 | 0.0121 | 0.0368 | 0.0218 | 0.0312 | 0.0145 | 0.0510 | 0.0223 | 0.8549 | 0.9273 | 0.0009 | 0.0040 | 0.0027 | 0.0132 | 0.0085 | 0.0238 | 0.0330 | 0.0886 | 0.0884 | 0.1799 | 0.1152 | 0.1786 | 0.1134 | 0.1310 | 0.1321 | 0.1481 | 0.5058 | 0.2328 | 0.0000 | 0.0028 | 0.0057 | 0.0164 | 0.0375 | 0.0805 | 0.0705 | 0.0898 | 0.6967 | 11 | 13 | 15 | 16 | 19 | 25 | 41 | 93 | 211 | 0.0930 | 8.04 | 3.824 | 0.6491 | 15845.6 | 5950000 | 2770000000 | 1510000000000 | 0.3766 | 0.2478 | 0.0298 | 0.0054 | 0.1067 | 0.0172 | 0.1592 | 0.0551 | 0.1827 | 0.1063 | 0.1820 | 0.1529 | 0.1451 | 0.1722 | 0.0871 | 0.1411 | 0.0659 | 0.1368 | 0.0416 | 0.2130 | 0.0004 | 0.0016 | 0.0017 | 0.0028 | 0.0045 | 0.0051 | 0.0117 | 0.0126 | 0.0354 | 0.0330 | 0.0450 | 0.0458 | 0.0377 | 0.0407 | 0.0557 | 0.0508 | 0.8078 | 0.8077 | 0.0000 | 0.0009 | 0.0007 | 0.0011 | 0.0037 | 0.0022 | 0.0114 | 0.0125 | 0.0389 | 0.0441 | 0.0647 | 0.0648 | 0.0431 | 0.0544 | 0.0638 | 0.0722 | 0.7737 | 0.7478 | 0.0011 | 0.0011 | 0.0023 | 0.0107 | 0.0370 | 0.0558 | 0.0367 | 0.0655 | 0.7899 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1118 | 571 | | 8114 | 11473 | 287.2 | 51.13 | 167.28 | 160.52 | 216 | 244 | 261 | 276 | 288 | 301 | 314 | 330 | 353 | 0.0825 | 946 | 0.972 | 44.55 | 15.65 | 1 | 0.0148 | 120 | 0.0020 | 14.93 | 6.529 | 0.2976 | 85117.2 | 26000000 | 8120000000 | 2600000000000 | 0.4373 | 0.2063 | 0.0005 | 0.0000 | 0.0015 | 0.0001 | 0.0027 | 0.0005 | 0.0121 | 0.0011 | 0.0320 | 0.0115 | 0.0585 | 0.0247 | 0.0605 | 0.0158 | 0.0827 | 0.0277 | 0.7495 | 0.9185 | 0.0003 | 0.0000 | 0.0003 | 0.0001 | 0.0010 | 0.0005 | 0.0049 | 0.0009 | 0.0130 | 0.0100 | 0.0228 | 0.0207 | 0.0186 | 0.0103 | 0.0277 | 0.0182 | 0.9114 | 0.9393 | 0.0075 | 0.0000 | 0.0197 | 0.0000 | 0.0254 | 0.0000 | 0.0630 | 0.0000 | 0.1006 | 0.0000 | 0.1410 | 0.0000 | 0.1194 | 0.0000 | 0.1391 | 0.0000 | 0.3844 | 0.0000 | 0.0017 | 0.0038 | 0.0094 | 0.0183 | 0.0428 | 0.0657 | 0.0729 | 0.0940 | 0.6914 | 14 | 20 | 33 | 56 | 109 | 178 | 247 | 321 | 407 | 0.0262 | 16.95 | 5.600 | 0.4608 | 53749.5 | 21300000 | 9500000000 | 4610000000000 | 0.5388 | 0.1195 | 0.0204 | 0.0036 | 0.0844 | 0.0071 | 0.2027 | 0.0554 | 0.2124 | 0.0996 | 0.1858 | 0.1765 | 0.1449 | 0.1957 | 0.0853 | 0.1425 | 0.0427 | 0.1367 | 0.0213 | 0.1828 | 0.0002 | 0.0002 | 0.0004 | 0.0000 | 0.0021 | 0.0010 | 0.0084 | 0.0088 | 0.0392 | 0.0312 | 0.0742 | 0.0636 | 0.0517 | 0.0429 | 0.0751 | 0.0700 | 0.7487 | 0.7823 | 0.0007 | 0.0000 | 0.0005 | 0.0016 | 0.0047 | 0.0066 | 0.0145 | 0.0172 | 0.0499 | 0.0620 | 0.0929 | 0.1039 | 0.0689 | 0.0823 | 0.0990 | 0.1175 | 0.6690 | 0.6089 | 0.0010 | 0.0008 | 0.0017 | 0.0109 | 0.0468 | 0.0801 | 0.0606 | 0.0887 | 0.7093 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 710 | 620 | | 2360 | 11953 | 110.5 | 24.96 | 211.01 | 181.60 | 79 | 90 | 97 | 103 | 109 | 115 | 122 | 130 | 142 | 0.0590 | 705 | 0.447 | 155.82 | 21.02 | 1 | 0.1462 | 345 | 0.0035 | 13.00 | 5.933 | 0.3106 | 12827.3 | 1560000 | 199000000 | 26300000000 | 0.4832 | 0.1861 | 0.0020 | 0.0000 | 0.0067 | 0.0009 | 0.0153 | 0.0032 | 0.0313 | 0.0074 | 0.0825 | 0.0300 | 0.1297 | 0.0669 | 0.1457 | 0.0646 | 0.1816 | 0.0817 | 0.4052 | 0.7453 | 0.0000 | 0.0000 | 0.0021 | 0.0004 | 0.0046 | 0.0022 | 0.0108 | 0.0043 | 0.0344 | 0.0195 | 0.0729 | 0.0468 | 0.0667 | 0.0299 | 0.0959 | 0.0468 | 0.7127 | 0.8501 | 0.0135 | 0.0000 | 0.0202 | 0.0142 | 0.0314 | 0.0638 | 0.0695 | 0.1702 | 0.1457 | 0.2766 | 0.1570 | 0.2057 | 0.1771 | 0.1135 | 0.1592 | 0.0922 | 0.2265 | 0.0638 | 0.0026 | 0.0026 | 0.0105 | 0.0438 | 0.0771 | 0.1402 | 0.1174 | 0.1446 | 0.4610 | 19 | 35 | 72 | 116 | 165 | 219 | 291 | 373 | 476 | 0.0088 | 40.77 | 6.716 | 0.3192 | 77499.7 | 35900000 | 19100000000 | 11300000000000 | 0.4707 | 0.1858 | 0.0171 | 0.0021 | 0.0769 | 0.0036 | 0.2135 | 0.0261 | 0.1532 | 0.0751 | 0.1780 | 0.1641 | 0.1449 | 0.2033 | 0.1100 | 0.1570 | 0.0651 | 0.1501 | 0.0414 | 0.2187 | 0.0003 | 0.0006 | 0.0014 | 0.0012 | 0.0042 | 0.0020 | 0.0115 | 0.0070 | 0.0431 | 0.0341 | 0.0776 | 0.0678 | 0.0739 | 0.0548 | 0.0927 | 0.0836 | 0.6952 | 0.7490 | 0.0010 | 0.0009 | 0.0021 | 0.0014 | 0.0067 | 0.0080 | 0.0200 | 0.0233 | 0.0562 | 0.0639 | 0.0998 | 0.1198 | 0.0814 | 0.0974 | 0.1131 | 0.1263 | 0.6197 | 0.5591 | 0.0002 | 0.0010 | 0.0051 | 0.0156 | 0.0562 | 0.0902 | 0.0770 | 0.0984 | 0.6564 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 755 | 233 | | 6882 | 11035 | 750.8 | 130.11 | 50.30 | 107.22 | 589 | 637 | 676 | 712 | 743 | 780 | 818 | 862 | 917 | 0.0847 | 935 | 0.936 | 120.35 | 37.05 | 2 | 0.0442 | 304 | 0.0010 | 30.30 | 7.224 | 0.2258 | 580634.0 | 462000000 | 378000000000 | 319000000000000 | 0.4407 | 0.2046 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0019 | 0.0001 | 0.0078 | 0.0003 | 0.0358 | 0.0142 | 0.0524 | 0.0228 | 0.0553 | 0.0152 | 0.0717 | 0.0231 | 0.7735 | 0.9243 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0031 | 0.0003 | 0.0186 | 0.0130 | 0.0277 | 0.0192 | 0.0279 | 0.0119 | 0.0379 | 0.0175 | 0.8843 | 0.9381 | 0.0012 | 0.0000 | 0.0048 | 0.0000 | 0.0203 | 0.0102 | 0.0501 | 0.1122 | 0.0776 | 0.0918 | 0.1241 | 0.1531 | 0.1181 | 0.1122 | 0.1050 | 0.1429 | 0.4988 | 0.3776 | 0.0009 | 0.0021 | 0.0039 | 0.0173 | 0.0318 | 0.0500 | 0.0518 | 0.0760 | 0.7662 | 7 | 9 | 11 | 12 | 15 | 19 | 26 | 42 | 126 | 0.0842 | 13.28 | 3.740 | 0.6597 | 14024.1 | 7570000 | 5380000000 | 4510000000000 | 0.4239 | 0.2208 | 0.0278 | 0.0089 | 0.0872 | 0.0149 | 0.1930 | 0.0343 | 0.1818 | 0.0961 | 0.1781 | 0.1586 | 0.1447 | 0.1571 | 0.1095 | 0.1400 | 0.0538 | 0.1482 | 0.0241 | 0.2420 | 0.0017 | 0.0034 | 0.0022 | 0.0044 | 0.0074 | 0.0065 | 0.0288 | 0.0266 | 0.0616 | 0.0536 | 0.0634 | 0.0615 | 0.0621 | 0.0663 | 0.0743 | 0.0844 | 0.6984 | 0.6933 | 0.0000 | 0.0013 | 0.0011 | 0.0013 | 0.0046 | 0.0019 | 0.0194 | 0.0183 | 0.0549 | 0.0593 | 0.0800 | 0.0732 | 0.0446 | 0.0511 | 0.0652 | 0.0650 | 0.7301 | 0.7287 | 0.0015 | 0.0025 | 0.0041 | 0.0259 | 0.0498 | 0.0747 | 0.0503 | 0.0711 | 0.7202 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1092 | 85 | | 5449 | 11450 | 95.0 | 23.16 | 86.45 | 60.42 | 71 | 77 | 81 | 86 | 91 | 95 | 101 | 110 | 125 | 0.0779 | 892 | 0.747 | 88.84 | 18.03 | 1 | 0.0376 | 205 | 0.0045 | 11.97 | 5.782 | 0.3166 | 9560.2 | 1030000 | 119000000 | 14900000000 | 0.4517 | 0.1982 | 0.0017 | 0.0000 | 0.0031 | 0.0000 | 0.0068 | 0.0002 | 0.0214 | 0.0018 | 0.0749 | 0.0225 | 0.1219 | 0.0393 | 0.1611 | 0.0466 | 0.2022 | 0.0826 | 0.4069 | 0.8069 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0029 | 0.0000 | 0.0120 | 0.0006 | 0.0334 | 0.0144 | 0.0484 | 0.0215 | 0.0776 | 0.0164 | 0.1074 | 0.0354 | 0.7154 | 0.9118 | 0.0096 | 0.0216 | 0.0160 | 0.0377 | 0.0310 | 0.0377 | 0.0652 | 0.0970 | 0.1485 | 0.1375 | 0.1485 | 0.1563 | 0.1239 | 0.1186 | 0.1528 | 0.1456 | 0.3045 | 0.2480 | 0.0022 | 0.0066 | 0.0254 | 0.0521 | 0.0902 | 0.1139 | 0.1248 | 0.1323 | 0.4525 | 21 | 33 | 45 | 59 | 73 | 90 | 110 | 133 | 169 | 0.0064 | 12.20 | 5.702 | 0.3894 | 11125.0 | 1840000 | 360000000 | 80100000000 | 0.5551 | 0.1175 | 0.0169 | 0.0024 | 0.0852 | 0.0089 | 0.1933 | 0.0316 | 0.2046 | 0.0842 | 0.1860 | 0.1444 | 0.1445 | 0.1944 | 0.0848 | 0.1671 | 0.0580 | 0.1675 | 0.0268 | 0.1994 | 0.0005 | 0.0011 | 0.0025 | 0.0020 | 0.0062 | 0.0051 | 0.0237 | 0.0164 | 0.0697 | 0.0496 | 0.1043 | 0.0775 | 0.0994 | 0.0776 | 0.1410 | 0.1147 | 0.5528 | 0.6561 | 0.0008 | 0.0052 | 0.0066 | 0.0098 | 0.0138 | 0.0265 | 0.0517 | 0.0622 | 0.1115 | 0.1306 | 0.1502 | 0.1614 | 0.1351 | 0.1383 | 0.1523 | 0.1453 | 0.3780 | 0.3206 | 0.0019 | 0.0031 | 0.0080 | 0.0331 | 0.0932 | 0.1245 | 0.1171 | 0.1566 | 0.4623 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 923 | 749 | | 18485 | 19144 | 337.4 | 48.91 | 148.53 | 162.19 | 268 | 300 | 318 | 331 | 344 | 355 | 367 | 380 | 396 | 0.0705 | 1349 | 1.142 | 100.72 | 39.20 | 2 | 0.0147 | 271 | 0.0025 | 9.90 | 6.327 | 0.3429 | 116234.0 | 40800000 | 14500000000 | 5230000000000 | 0.4218 | 0.2181 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0027 | 0.0001 | 0.0083 | 0.0008 | 0.0174 | 0.0071 | 0.0285 | 0.0145 | 0.0316 | 0.0074 | 0.0551 | 0.0119 | 0.8546 | 0.9581 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0001 | 0.0022 | 0.0008 | 0.0085 | 0.0071 | 0.0136 | 0.0145 | 0.0122 | 0.0074 | 0.0186 | 0.0119 | 0.9443 | 0.9581 | 0.0326 | 0.0000 | 0.0692 | 0.0000 | 0.0794 | 0.0000 | 0.1090 | 0.0000 | 0.1517 | 0.0000 | 0.1415 | 0.0000 | 0.1395 | 0.0000 | 0.1446 | 0.0000 | 0.1324 | 0.0000 | 0.0028 | 0.0050 | 0.0091 | 0.0138 | 0.0293 | 0.0412 | 0.0457 | 0.0737 | 0.7793 | 23 | 31 | 42 | 57 | 77 | 109 | 167 | 256 | 387 | 0.0183 | 13.36 | 5.441 | 0.5104 | 48364.8 | 22700000 | 12800000000 | 8140000000000 | 0.3890 | 0.2609 | 0.0233 | 0.0013 | 0.0952 | 0.0085 | 0.1700 | 0.0530 | 0.1578 | 0.1011 | 0.1966 | 0.1512 | 0.1445 | 0.1702 | 0.0908 | 0.1386 | 0.0714 | 0.1404 | 0.0504 | 0.2358 | 0.0001 | 0.0003 | 0.0008 | 0.0009 | 0.0026 | 0.0044 | 0.0128 | 0.0124 | 0.0492 | 0.0417 | 0.0708 | 0.0661 | 0.0547 | 0.0448 | 0.0827 | 0.0706 | 0.7262 | 0.7587 | 0.0007 | 0.0006 | 0.0009 | 0.0017 | 0.0035 | 0.0058 | 0.0196 | 0.0235 | 0.0581 | 0.0707 | 0.0989 | 0.0946 | 0.0629 | 0.0773 | 0.0941 | 0.1006 | 0.6612 | 0.6252 | 0.0000 | 0.0010 | 0.0043 | 0.0159 | 0.0522 | 0.0864 | 0.0570 | 0.0870 | 0.6963 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1116 | 643 | | 4192 | 3538 | 101.2 | 30.48 | 158.91 | 113.21 | 66 | 76 | 84 | 91 | 97 | 104 | 112 | 125 | 141 | 0.1888 | 668 | 0.252 | 105.39 | 16.55 | 4 | 0.1069 | 448 | 0.0013 | 39.51 | 6.913 | 0.1929 | 11171.4 | 1340000 | 175000000 | 24600000000 | 0.4594 | 0.2026 | 0.0014 | 0.0000 | 0.0041 | 0.0009 | 0.0124 | 0.0023 | 0.0464 | 0.0096 | 0.1319 | 0.0422 | 0.1994 | 0.0776 | 0.1641 | 0.0774 | 0.1567 | 0.1235 | 0.2835 | 0.6665 | 0.0006 | 0.0000 | 0.0010 | 0.0005 | 0.0022 | 0.0010 | 0.0128 | 0.0053 | 0.0491 | 0.0264 | 0.0952 | 0.0467 | 0.0789 | 0.0345 | 0.1084 | 0.0632 | 0.6518 | 0.8224 | 0.0000 | 0.0073 | 0.0032 | 0.0218 | 0.0170 | 0.0291 | 0.0668 | 0.1065 | 0.1188 | 0.1574 | 0.1739 | 0.1695 | 0.1294 | 0.1283 | 0.1379 | 0.1259 | 0.3531 | 0.2542 | 0.0016 | 0.0037 | 0.0132 | 0.0390 | 0.0895 | 0.1311 | 0.1101 | 0.1411 | 0.4708 | 37 | 66 | 88 | 111 | 133 | 160 | 195 | 241 | 311 | 0.0052 | 18.73 | 5.833 | 0.3641 | 38065.2 | 12000000 | 4640000000 | 2080000000000 | 0.5210 | 0.1303 | 0.0169 | 0.0013 | 0.0663 | 0.0074 | 0.1808 | 0.0207 | 0.1873 | 0.0702 | 0.1625 | 0.1318 | 0.1443 | 0.1839 | 0.0845 | 0.1498 | 0.0754 | 0.1639 | 0.0819 | 0.2709 | 0.0000 | 0.0000 | 0.0027 | 0.0009 | 0.0038 | 0.0021 | 0.0279 | 0.0141 | 0.0681 | 0.0513 | 0.1217 | 0.0881 | 0.1045 | 0.0783 | 0.1436 | 0.1245 | 0.5279 | 0.6407 | 0.0009 | 0.0047 | 0.0000 | 0.0107 | 0.0119 | 0.0225 | 0.0574 | 0.0664 | 0.1240 | 0.1163 | 0.1559 | 0.1720 | 0.1276 | 0.1139 | 0.1586 | 0.1649 | 0.3637 | 0.3286 | 0.0014 | 0.0028 | 0.0104 | 0.0369 | 0.0828 | 0.1711 | 0.1113 | 0.1474 | 0.4360 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 218 | 312 | | 2655 | 8245 | 132.8 | 44.21 | 178.73 | 118.36 | 91 | 99 | 108 | 117 | 125 | 134 | 142 | 155 | 176 | 0.0813 | 670 | 0.683 | 79.32 | 27.66 | 1 | 0.0968 | 257 | 0.0031 | 18.62 | 6.095 | 0.3246 | 19582.2 | 3340000 | 689000000 | 173000000000 | 0.4385 | 0.1979 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0062 | 0.0004 | 0.0256 | 0.0020 | 0.0622 | 0.0283 | 0.1119 | 0.0557 | 0.1140 | 0.0414 | 0.1298 | 0.0602 | 0.5497 | 0.8120 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0037 | 0.0004 | 0.0115 | 0.0015 | 0.0314 | 0.0216 | 0.0492 | 0.0352 | 0.0413 | 0.0250 | 0.0581 | 0.0367 | 0.8043 | 0.8796 | 0.0043 | 0.0000 | 0.0065 | 0.0100 | 0.0151 | 0.0100 | 0.0454 | 0.0350 | 0.1080 | 0.1100 | 0.1058 | 0.1600 | 0.0778 | 0.0750 | 0.1231 | 0.1350 | 0.5140 | 0.4650 | 0.0027 | 0.0018 | 0.0100 | 0.0255 | 0.0656 | 0.0974 | 0.0792 | 0.1193 | 0.5984 | 59 | 76 | 93 | 115 | 144 | 182 | 225 | 275 | 351 | 0.0020 | 52.90 | 6.928 | 0.2551 | 45949.6 | 15000000 | 5740000000 | 2430000000000 | 0.5074 | 0.1593 | 0.0155 | 0.0010 | 0.0882 | 0.0092 | 0.2007 | 0.0209 | 0.1771 | 0.0654 | 0.1630 | 0.1485 | 0.1441 | 0.1660 | 0.0774 | 0.1622 | 0.0566 | 0.1523 | 0.0774 | 0.2745 | 0.0005 | 0.0002 | 0.0027 | 0.0019 | 0.0060 | 0.0044 | 0.0169 | 0.0095 | 0.0638 | 0.0525 | 0.1051 | 0.0712 | 0.0744 | 0.0711 | 0.1097 | 0.0969 | 0.6210 | 0.6922 | 0.0011 | 0.0039 | 0.0068 | 0.0123 | 0.0139 | 0.0178 | 0.0444 | 0.0468 | 0.0889 | 0.0868 | 0.1213 | 0.1391 | 0.0998 | 0.1297 | 0.1348 | 0.1440 | 0.4889 | 0.4196 | 0.0009 | 0.0036 | 0.0083 | 0.0238 | 0.0753 | 0.1202 | 0.0940 | 0.1196 | 0.5542 | ||
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1098 | 160 | | 13724 | 21102 | 109.6 | 32.03 | 139.67 | 113.32 | 75 | 84 | 91 | 97 | 104 | 112 | 121 | 133 | 152 | 0.0598 | 1262 | 0.543 | 155.77 | 38.28 | 1 | 0.0358 | 491 | 0.0012 | 36.99 | 7.099 | 0.2067 | 13040.5 | 1690000 | 237000000 | 36400000000 | 0.4757 | 0.1867 | 0.0010 | 0.0001 | 0.0041 | 0.0003 | 0.0130 | 0.0016 | 0.0426 | 0.0043 | 0.0995 | 0.0236 | 0.1665 | 0.0560 | 0.1630 | 0.0574 | 0.1878 | 0.0954 | 0.3226 | 0.7614 | 0.0005 | 0.0001 | 0.0013 | 0.0001 | 0.0034 | 0.0002 | 0.0125 | 0.0008 | 0.0402 | 0.0130 | 0.0734 | 0.0252 | 0.0716 | 0.0218 | 0.1009 | 0.0456 | 0.6963 | 0.8934 | 0.0044 | 0.0054 | 0.0078 | 0.0168 | 0.0271 | 0.0337 | 0.0640 | 0.0804 | 0.1118 | 0.1692 | 0.1406 | 0.1937 | 0.1349 | 0.1026 | 0.1386 | 0.1394 | 0.3707 | 0.2588 | 0.0024 | 0.0058 | 0.0129 | 0.0351 | 0.0814 | 0.1154 | 0.0950 | 0.1140 | 0.5380 | 25 | 40 | 60 | 83 | 110 | 142 | 177 | 222 | 298 | 0.0094 | 10.78 | 5.597 | 0.4544 | 32349.4 | 10000000 | 3730000000 | 1590000000000 | 0.5105 | 0.1695 | 0.0131 | 0.0019 | 0.0728 | 0.0040 | 0.1644 | 0.0224 | 0.1683 | 0.0713 | 0.1736 | 0.1476 | 0.1439 | 0.1890 | 0.1111 | 0.1477 | 0.0831 | 0.1506 | 0.0697 | 0.2653 | 0.0009 | 0.0007 | 0.0013 | 0.0014 | 0.0035 | 0.0034 | 0.0133 | 0.0126 | 0.0502 | 0.0386 | 0.0839 | 0.0657 | 0.0680 | 0.0578 | 0.1044 | 0.0854 | 0.6745 | 0.7344 | 0.0012 | 0.0013 | 0.0045 | 0.0041 | 0.0086 | 0.0141 | 0.0281 | 0.0380 | 0.0821 | 0.1031 | 0.1290 | 0.1509 | 0.1030 | 0.1107 | 0.1319 | 0.1375 | 0.5116 | 0.4403 | 0.0013 | 0.0019 | 0.0052 | 0.0196 | 0.0680 | 0.1022 | 0.0904 | 0.1250 | 0.5864 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 347 | 300 | | 2888 | 7129 | 611.2 | 202.03 | 52.68 | 78.44 | 344 | 415 | 484 | 545 | 608 | 668 | 727 | 793 | 895 | 0.0933 | 665 | 0.692 | 73.88 | 19.31 | 5 | 0.0793 | 229 | 0.0006 | 88.70 | 7.545 | 0.1281 | 414341.0 | 304000000 | 237000000000 | 194000000000000 | 0.4195 | 0.2137 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0014 | 0.0318 | 0.0028 | 0.1133 | 0.0503 | 0.2017 | 0.0878 | 0.1279 | 0.0617 | 0.1536 | 0.0897 | 0.3691 | 0.7061 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0008 | 0.0040 | 0.0012 | 0.0334 | 0.0335 | 0.0703 | 0.0467 | 0.0389 | 0.0283 | 0.0573 | 0.0463 | 0.7956 | 0.8432 | 0.0024 | 0.0000 | 0.0012 | 0.0050 | 0.0071 | 0.0075 | 0.0214 | 0.0150 | 0.0820 | 0.1075 | 0.1023 | 0.1425 | 0.0880 | 0.0650 | 0.0892 | 0.1175 | 0.6064 | 0.5400 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0510 | 0.0944 | 0.0573 | 0.0839 | 0.7056 | 9 | 12 | 14 | 18 | 24 | 33 | 47 | 68 | 122 | 0.0416 | 14.75 | 4.364 | 0.5754 | 8927.3 | 2850000 | 1210000000 | 606000000000 | 0.5155 | 0.1457 | 0.0091 | 0.0030 | 0.0653 | 0.0089 | 0.1554 | 0.0244 | 0.2324 | 0.0654 | 0.1932 | 0.1426 | 0.1436 | 0.1717 | 0.1097 | 0.1794 | 0.0627 | 0.1747 | 0.0287 | 0.2299 | 0.0004 | 0.0014 | 0.0052 | 0.0037 | 0.0100 | 0.0071 | 0.0247 | 0.0216 | 0.0715 | 0.0632 | 0.1001 | 0.0781 | 0.0811 | 0.0784 | 0.1188 | 0.1055 | 0.5882 | 0.6410 | 0.0013 | 0.0024 | 0.0084 | 0.0102 | 0.0149 | 0.0071 | 0.0292 | 0.0314 | 0.0876 | 0.0949 | 0.1181 | 0.1459 | 0.0876 | 0.0933 | 0.1207 | 0.1231 | 0.5321 | 0.4918 | 0.0016 | 0.0058 | 0.0111 | 0.0329 | 0.0853 | 0.1081 | 0.0859 | 0.1171 | 0.5522 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 945 | 791 | | 7136 | 8653 | 396.4 | 68.86 | 331.09 | 487.17 | 292 | 338 | 365 | 386 | 406 | 423 | 439 | 454 | 478 | 0.0953 | 825 | 1.046 | 109.66 | 38.48 | 6 | 0.0419 | 299 | 0.0024 | 9.08 | 6.362 | 0.3660 | 161888.0 | 67800000 | 29000000000 | 12700000000000 | 0.4181 | 0.2153 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0000 | 0.0079 | 0.0011 | 0.0218 | 0.0106 | 0.0533 | 0.0271 | 0.0385 | 0.0132 | 0.0585 | 0.0186 | 0.8142 | 0.9294 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0011 | 0.0113 | 0.0105 | 0.0289 | 0.0260 | 0.0141 | 0.0119 | 0.0204 | 0.0173 | 0.9222 | 0.9333 | 0.0066 | 0.0000 | 0.0066 | 0.0000 | 0.0263 | 0.0000 | 0.0447 | 0.0000 | 0.1092 | 0.0000 | 0.1184 | 0.0000 | 0.1158 | 0.0000 | 0.1382 | 0.0000 | 0.4342 | 0.0000 | 0.0005 | 0.0015 | 0.0051 | 0.0101 | 0.0281 | 0.0398 | 0.0367 | 0.0529 | 0.8252 | 10 | 12 | 15 | 26 | 85 | 211 | 381 | 631 | 998 | 0.1055 | 26.80 | 5.014 | 0.5502 | 346927.0 | 541000000 | 1110000000000 | 2.77E+15 | 0.4761 | 0.1685 | 0.0161 | 0.0031 | 0.0966 | 0.0086 | 0.1804 | 0.0350 | 0.1739 | 0.0871 | 0.1643 | 0.1540 | 0.1433 | 0.1882 | 0.0934 | 0.1407 | 0.0805 | 0.1198 | 0.0515 | 0.2636 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0025 | 0.0017 | 0.0063 | 0.0068 | 0.0348 | 0.0256 | 0.0659 | 0.0501 | 0.0446 | 0.0400 | 0.0681 | 0.0535 | 0.7768 | 0.8202 | 0.0000 | 0.0004 | 0.0004 | 0.0018 | 0.0039 | 0.0049 | 0.0102 | 0.0123 | 0.0481 | 0.0511 | 0.0777 | 0.0886 | 0.0560 | 0.0675 | 0.0765 | 0.0825 | 0.7272 | 0.6909 | 0.0000 | 0.0004 | 0.0036 | 0.0093 | 0.0411 | 0.0750 | 0.0496 | 0.0650 | 0.7562 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1160 | 141 | | 3233 | 11358 | 59.9 | 15.14 | 124.51 | 201.52 | 40 | 47 | 52 | 56 | 59 | 63 | 68 | 73 | 80 | 0.0812 | 922 | 1.116 | 66.27 | 24.02 | 8 | 0.0520 | 168 | 0.0039 | 9.71 | 5.841 | 0.3283 | 3816.7 | 256199 | 18000000 | 1310000000 | 0.4210 | 0.2075 | 0.0016 | 0.0007 | 0.0121 | 0.0007 | 0.0236 | 0.0021 | 0.0356 | 0.0084 | 0.0773 | 0.0453 | 0.1135 | 0.0541 | 0.1321 | 0.0699 | 0.1908 | 0.1173 | 0.4134 | 0.7015 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0058 | 0.0007 | 0.0136 | 0.0046 | 0.0342 | 0.0320 | 0.0427 | 0.0346 | 0.0497 | 0.0369 | 0.0730 | 0.0515 | 0.7767 | 0.8398 | 0.0133 | 0.0415 | 0.0146 | 0.0553 | 0.0320 | 0.0968 | 0.0626 | 0.0829 | 0.0786 | 0.1613 | 0.1012 | 0.1705 | 0.1318 | 0.1475 | 0.1491 | 0.1521 | 0.4168 | 0.0922 | 0.0063 | 0.0101 | 0.0184 | 0.0380 | 0.0582 | 0.0671 | 0.0880 | 0.1063 | 0.6076 | 16 | 20 | 23 | 28 | 42 | 71 | 118 | 184 | 325 | 0.0815 | 10.02 | 4.228 | 0.6192 | 56109.0 | 50800000 | 64300000000 | 94700000000000 | 0.6731 | 0.0824 | 0.0382 | 0.0025 | 0.1393 | 0.0177 | 0.1670 | 0.0809 | 0.1460 | 0.1089 | 0.1651 | 0.1648 | 0.1431 | 0.1712 | 0.1002 | 0.1344 | 0.0716 | 0.1363 | 0.0296 | 0.1834 | 0.0000 | 0.0004 | 0.0018 | 0.0020 | 0.0063 | 0.0029 | 0.0266 | 0.0186 | 0.0673 | 0.0669 | 0.0986 | 0.0822 | 0.0819 | 0.0716 | 0.1122 | 0.1042 | 0.6054 | 0.6512 | 0.0004 | 0.0029 | 0.0043 | 0.0062 | 0.0093 | 0.0083 | 0.0377 | 0.0360 | 0.0890 | 0.0989 | 0.1328 | 0.1320 | 0.0800 | 0.0757 | 0.1120 | 0.1105 | 0.5345 | 0.5294 | 0.0012 | 0.0027 | 0.0067 | 0.0307 | 0.0828 | 0.1186 | 0.0791 | 0.1205 | 0.5577 |