High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

Filter results: >>>>
Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 1197 683 image if available 3842 9565 478.9 116.21 90.11 172.80 337 392 429 457 482 506 537 577 631 0.0859 822 0.710 156.82 38.91 4 0.1221 469 0.0007 53.66 7.428 0.1677 242853.0
129000000
70500000000
39900000000000
0.4854 0.1685 0.0000 0.0000 0.0000 0.0000 0.0025 0.0003 0.0110 0.0026 0.0591 0.0372 0.0922 0.0507 0.0761 0.0389 0.1016 0.0595 0.6575 0.8108 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0048 0.0008 0.0315 0.0304 0.0481 0.0395 0.0344 0.0268 0.0452 0.0392 0.8356 0.8633 0.0025 0.0000 0.0076 0.0000 0.0051 0.0000 0.0242 0.0000 0.0509 0.0000 0.0738 0.0000 0.0725 0.0000 0.0725 0.0000 0.6908 0.0000 0.0010 0.0020 0.0061 0.0137 0.0461 0.0587 0.0613 0.0886 0.7225 9 11 13 14 17 22 47 128 270 0.1570 5.23 3.104 0.6201 37975.0
27200000
25100000000
27100000000000
0.6578 0.0700 0.0976 0.0024 0.2415 0.0468 0.2512 0.1909 0.0976 0.1741 0.1146 0.1801 0.0951 0.1381 0.0439 0.1092 0.0390 0.0708 0.0195 0.0876 0.0004 0.0000 0.0004 0.0011 0.0039 0.0036 0.0162 0.0184 0.0774 0.0640 0.1086 0.1081 0.0632 0.0669 0.0968 0.0872 0.6331 0.6506 0.0000 0.0005 0.0024 0.0041 0.0042 0.0057 0.0264 0.0316 0.0792 0.0756 0.1216 0.1366 0.0726 0.0694 0.0975 0.1009 0.5961 0.5756 0.0000 0.0022 0.0047 0.0186 0.0768 0.1195 0.0673 0.0928 0.6182
Hs 578T A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 369 897 image if available 508 2542 168.7 101.76 78.27 159.27 36 52 79 122 170 212 254 284 304 0.1326 337 0.963 124.46 46.23 1 0.6909 351 0.0029 78.06 5.974 0.1808 38792.0
10100000
2760000000
778000000000
0.2699 0.3263 0.0000 0.0000 0.0278 0.0000 0.2917 0.0000 0.3889 0.0065 0.1528 0.1883 0.0556 0.3701 0.0556 0.2013 0.0278 0.0909 0.0000 0.1429 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0104 0.0000 0.0519 0.0604 0.0900 0.0876 0.0484 0.0363 0.0727 0.0695 0.7266 0.7462 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0092 0.0113 0.0553 0.0791 0.1244 0.1017 0.0369 0.0508 0.0691 0.0904 0.7051 0.6667 0.0000 0.0000 0.0039 0.0039 0.0547 0.1094 0.0352 0.0742 0.7188 14 16 18 20 22 28 42 75 198 0.0967 17.71 3.564 0.6230 31483.0
24000000
22900000000
24100000000000
0.5318 0.1158 0.1119 0.0000 0.3731 0.0552 0.2836 0.1595 0.0970 0.2209 0.0672 0.2331 0.0299 0.1626 0.0299 0.0890 0.0075 0.0491 0.0000 0.0307 0.0000 0.0000 0.0035 0.0014 0.0086 0.0043 0.0276 0.0340 0.1261 0.1007 0.1572 0.1277 0.0950 0.0879 0.1295 0.1433 0.4525 0.5007 0.0000 0.0026 0.0112 0.0026 0.0067 0.0211 0.0315 0.0554 0.1393 0.1135 0.1685 0.1821 0.0921 0.1055 0.1573 0.1293 0.3933 0.3879 0.0000 0.0040 0.0140 0.0460 0.1180 0.1560 0.0960 0.1540 0.4120
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 461 123 image if available 3257 6809 514.7 105.53 61.25 124.20 368 433 474 500 525 551 579 608 638 0.0824 561 0.766 87.00 16.03 3 0.0620 202 0.0010 52.75 7.148 0.1825 276060.0
153000000
86800000000
50400000000000
0.4286 0.2196 0.0000 0.0000 0.0014 0.0000 0.0068 0.0000 0.0140 0.0013 0.0512 0.0198 0.0978 0.0406 0.0965 0.0227 0.1277 0.0373 0.6046 0.8782 0.0000 0.0000 0.0000 0.0000 0.0004 0.0000 0.0029 0.0013 0.0220 0.0197 0.0447 0.0384 0.0293 0.0184 0.0411 0.0288 0.8596 0.8934 0.0077 0.1333 0.0173 0.1333 0.0288 0.0667 0.0865 0.1333 0.1404 0.2667 0.1442 0.1333 0.1231 0.0000 0.1654 0.1333 0.2865 0.0000 0.0011 0.0023 0.0079 0.0186 0.0514 0.0814 0.0729 0.1040 0.6605 7 9 11 12 14 19 31 56 175 0.1883 7.43 3.201 0.7374 19174.6
10600000
7360000000
5780000000000
0.4921 0.1647 0.0338 0.0142 0.0549 0.0252 0.0717 0.0377 0.0928 0.0660 0.1392 0.0849 0.1814 0.1289 0.2363 0.1321 0.1097 0.1525 0.0802 0.3585 0.0034 0.0045 0.0048 0.0078 0.0034 0.0111 0.0109 0.0167 0.0212 0.0279 0.0519 0.0507 0.0355 0.0423 0.0444 0.0591 0.8245 0.7799 0.0000 0.0000 0.0008 0.0000 0.0016 0.0000 0.0073 0.0078 0.0334 0.0336 0.0465 0.0509 0.0302 0.0259 0.0522 0.0578 0.8280 0.8240 0.0008 0.0008 0.0046 0.0106 0.0236 0.0540 0.0274 0.0547 0.8237
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 458 196 image if available 2487 4852 502.4 108.13 28.97 67.04 323 396 462 498 525 549 572 595 625 0.1008 489 1.136 122.50 41.00 3 0.1186 295 0.0011 45.67 6.999 0.1815 264107.0
144000000
80400000000
45900000000000
0.4074 0.2236 0.0000 0.0000 0.0007 0.0017 0.0013 0.0017 0.0137 0.0038 0.0586 0.0196 0.1036 0.0325 0.0971 0.0282 0.1153 0.0440 0.6098 0.8684 0.0000 0.0000 0.0000 0.0017 0.0000 0.0017 0.0036 0.0038 0.0214 0.0196 0.0300 0.0311 0.0254 0.0230 0.0376 0.0358 0.8821 0.8834 0.0000 0.0000 0.0093 0.5000 0.0231 0.5000 0.0579 0.0000 0.1435 0.0000 0.2176 0.0000 0.0995 0.0000 0.1435 0.0000 0.3056 0.0000 0.0000 0.0021 0.0027 0.0103 0.0397 0.0637 0.0582 0.0794 0.7440 7 9 10 12 13 16 20 25 39 0.2290 1.64 2.351 0.8187 5332.5
2350000
1240000000
703000000000
0.6224 0.1004 0.0481 0.0325 0.0611 0.0293 0.0722 0.0357 0.0907 0.0325 0.1389 0.0523 0.1889 0.0722 0.1611 0.1094 0.1333 0.1665 0.1056 0.4695 0.0208 0.0226 0.0271 0.0203 0.0253 0.0231 0.0316 0.0220 0.0479 0.0365 0.0949 0.0602 0.0723 0.0747 0.1102 0.1169 0.5700 0.6238 0.0212 0.0086 0.0194 0.0107 0.0212 0.0086 0.0300 0.0193 0.0423 0.0428 0.0758 0.0600 0.0406 0.0450 0.0882 0.0878 0.6614 0.7173 0.0202 0.0265 0.0277 0.0429 0.0542 0.0845 0.0605 0.0782 0.6053
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 886 459 image if available 3618 10342 579.4 120.00 16.41 14.61 402 502 541 570 596 621 644 667 707 0.0617 638 0.872 72.47 21.02 4 0.0506 183 0.0010 57.19 7.152 0.1994 350122.0
218000000
140000000000
91900000000000
0.4429 0.2126 0.0004 0.0000 0.0000 0.0003 0.0008 0.0006 0.0086 0.0012 0.0409 0.0173 0.0601 0.0352 0.0530 0.0212 0.0823 0.0391 0.7539 0.8852 0.0000 0.0000 0.0000 0.0003 0.0000 0.0006 0.0013 0.0009 0.0167 0.0167 0.0279 0.0301 0.0196 0.0140 0.0382 0.0289 0.8963 0.9084 0.0088 0.0000 0.0044 0.0980 0.0199 0.0000 0.0508 0.0980 0.1258 0.1569 0.1523 0.1765 0.1192 0.0588 0.1501 0.1373 0.3687 0.2745 0.0000 0.0005 0.0063 0.0146 0.0466 0.0777 0.0670 0.0869 0.7005 6 8 9 11 13 15 17 20 29 0.2798 0.41 1.932 0.8610 482.7
28156.6
2820000
388000000
0.4309 0.2072 0.0435 0.0205 0.0470 0.0372 0.0509 0.0455 0.0895 0.0516 0.1126 0.0612 0.1545 0.0846 0.2073 0.1008 0.1905 0.1706 0.1043 0.4280 0.0225 0.0151 0.0206 0.0257 0.0213 0.0301 0.0324 0.0319 0.0506 0.0421 0.0689 0.0635 0.0845 0.0648 0.1386 0.1026 0.5606 0.6242 0.0382 0.0267 0.0326 0.0130 0.0336 0.0298 0.0424 0.0360 0.0559 0.0477 0.0634 0.0701 0.0662 0.0775 0.1058 0.0967 0.5620 0.6026 0.0209 0.0300 0.0386 0.0551 0.0695 0.0973 0.0921 0.1086 0.4879
MCF 10A Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 576 951 image if available 438 2028 54.0 7.53 156.62 225.49 45 48 49 51 54 55 57 60 63 0.1686 342 0.895 78.01 22.20 1 0.4566 200 0.0096 10.55 4.855 0.3142 2971.3
166797
9560000
559000000
0.3875 0.2379 0.0000 0.0000 0.0000 0.0000 0.0079 0.0023 0.0262 0.0092 0.0945 0.0624 0.1260 0.0901 0.1811 0.0693 0.2520 0.1085 0.3123 0.6582 0.0000 0.0000 0.0000 0.0000 0.0072 0.0023 0.0193 0.0091 0.0578 0.0594 0.0988 0.0868 0.1012 0.0548 0.1518 0.0868 0.5639 0.7009 0.1765 0.0000 0.1765 0.2000 0.0588 0.2000 0.1765 0.6000 0.1176 0.0000 0.0294 0.0000 0.1765 0.0000 0.0882 0.0000 0.0000 0.0000 0.0136 0.0318 0.0227 0.0773 0.1364 0.1364 0.1500 0.2091 0.2227 17 21 28 41 64 99 142 241 425 0.0260 58.20 5.100 0.4350 75349.7
58100000
55000000000
57800000000000
0.4831 0.1439 0.1056 0.0000 0.2609 0.0221 0.2050 0.1838 0.0870 0.1569 0.1242 0.1936 0.0870 0.1201 0.0683 0.0760 0.0435 0.1176 0.0186 0.1299 0.0030 0.0000 0.0030 0.0036 0.0151 0.0059 0.0256 0.0119 0.0935 0.0973 0.1704 0.1269 0.0905 0.0973 0.1297 0.1329 0.4691 0.5243 0.0020 0.0000 0.0060 0.0069 0.0159 0.0207 0.0239 0.0345 0.1076 0.1310 0.1853 0.1816 0.1036 0.0989 0.1474 0.1402 0.4084 0.3862 0.0000 0.0035 0.0159 0.0265 0.1044 0.1805 0.0973 0.1274 0.4442
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 365 353 image if available 5969 9686 532.6 131.58 28.76 57.02 329 402 483 536 572 597 619 644 676 0.0840 814 1.039 109.33 39.70 3 0.0476 284 0.0007 61.44 7.562 0.1890 300963.0
177000000
107000000000
65900000000000
0.4153 0.2188 0.0006 0.0000 0.0018 0.0000 0.0036 0.0002 0.0109 0.0011 0.0555 0.0200 0.0772 0.0344 0.0832 0.0215 0.1212 0.0340 0.6460 0.8888 0.0000 0.0000 0.0000 0.0000 0.0002 0.0002 0.0015 0.0011 0.0246 0.0200 0.0316 0.0336 0.0250 0.0204 0.0396 0.0310 0.8774 0.8937 0.0055 0.0000 0.0071 0.0000 0.0188 1.0000 0.0290 0.0000 0.0565 0.0000 0.0863 0.0000 0.0847 0.0000 0.1145 0.0000 0.5976 0.0000 0.0003 0.0000 0.0019 0.0047 0.0314 0.0394 0.0411 0.0607 0.8205 8 10 11 13 16 21 27 36 51 0.1769 0.75 1.769 0.6861 4078.2
2130000
1520000000
1200000000000
0.5279 0.1420 0.0341 0.0214 0.0384 0.0239 0.0803 0.0306 0.0852 0.0415 0.1165 0.0580 0.1541 0.0685 0.1925 0.0928 0.1996 0.1557 0.0994 0.5076 0.0086 0.0112 0.0106 0.0098 0.0185 0.0121 0.0222 0.0179 0.0376 0.0331 0.0539 0.0414 0.0587 0.0485 0.0952 0.0713 0.6946 0.7548 0.0124 0.0117 0.0133 0.0123 0.0143 0.0178 0.0219 0.0270 0.0505 0.0596 0.0657 0.0713 0.0634 0.0774 0.0991 0.1167 0.6594 0.6063 0.0141 0.0137 0.0213 0.0260 0.0416 0.0513 0.0604 0.0853 0.6863
Hs 578T Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 903 431 image if available 54613 82874 84.8 46.65 114.00 205.41 23 28 54 73 87 99 112 126 146 0.0303 2514 0.607 231.82 52.47 24 0.0118 645 0.0046 13.65 6.351 0.3627 9367.0
1190000
165000000
24700000000
0.5125 0.1476 0.0017 0.0007 0.0076 0.0010 0.0380 0.0040 0.0801 0.0150 0.1435 0.0575 0.1828 0.1084 0.1675 0.1062 0.1626 0.1362 0.2163 0.5709 0.0002 0.0000 0.0004 0.0000 0.0014 0.0002 0.0055 0.0015 0.0213 0.0119 0.0388 0.0234 0.0374 0.0198 0.0551 0.0316 0.8399 0.9117 0.0006 0.0018 0.0028 0.0048 0.0065 0.0130 0.0229 0.0391 0.0576 0.0808 0.0882 0.1189 0.0857 0.0985 0.1117 0.1228 0.6241 0.5203 0.0004 0.0014 0.0040 0.0124 0.0339 0.0605 0.0589 0.0824 0.7461 10 12 13 15 18 26 61 174 383 0.2390 19.16 3.787 0.6638 55186.4
40400000
36400000000
37700000000000
0.4605 0.1949 0.1576 0.0035 0.3814 0.0611 0.3071 0.3277 0.0839 0.2234 0.0408 0.1726 0.0158 0.1086 0.0071 0.0487 0.0039 0.0298 0.0026 0.0245 0.0001 0.0001 0.0006 0.0003 0.0013 0.0008 0.0117 0.0106 0.0652 0.0602 0.1027 0.0939 0.0640 0.0575 0.0983 0.0881 0.6561 0.6885 0.0000 0.0004 0.0009 0.0009 0.0020 0.0025 0.0164 0.0184 0.0742 0.0778 0.1173 0.1225 0.0764 0.0817 0.1085 0.1098 0.6044 0.5860 0.0001 0.0002 0.0017 0.0132 0.0722 0.1105 0.0693 0.1056 0.6272
SK-BR-3 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 1178 149 image if available 2587 12832 62.1 10.66 74.22 169.03 47 54 57 60 63 65 68 71 75 0.0646 829 0.944 80.06 19.03 2 0.0723 187 0.0369 1.29 3.638 0.6360 3969.1
260301
17500000
1200000000
0.4305 0.2137 0.0020 0.0000 0.0020 0.0004 0.0055 0.0008 0.0201 0.0075 0.0472 0.0210 0.0693 0.0334 0.0844 0.0346 0.1920 0.0516 0.5774 0.8507 0.0004 0.0000 0.0004 0.0000 0.0018 0.0004 0.0079 0.0059 0.0238 0.0192 0.0331 0.0298 0.0348 0.0271 0.0591 0.0365 0.8386 0.8811 0.0719 0.0968 0.1079 0.1290 0.0755 0.1935 0.1151 0.0968 0.1043 0.1613 0.1187 0.1613 0.1475 0.0968 0.0827 0.0645 0.1763 0.0000 0.0036 0.0107 0.0220 0.0377 0.0519 0.0732 0.1087 0.1741 0.5181 15 19 23 28 32 38 43 50 94 0.1646 3.32 2.652 0.8090 34078.2
30400000
31700000000
35800000000000
0.6942 0.0754 0.1033 0.0274 0.0813 0.0364 0.0769 0.0502 0.0769 0.0707 0.1319 0.1021 0.1275 0.1360 0.1319 0.1585 0.1275 0.1667 0.1429 0.2520 0.0237 0.0180 0.0188 0.0239 0.0094 0.0319 0.0066 0.0430 0.0248 0.0663 0.0370 0.0857 0.0304 0.1021 0.0679 0.1201 0.7815 0.5089 0.0044 0.0017 0.0044 0.0035 0.0074 0.0095 0.0118 0.0173 0.0376 0.0528 0.0516 0.0692 0.0553 0.0614 0.1061 0.0882 0.7214 0.6964 0.0006 0.0038 0.0038 0.0101 0.0258 0.0396 0.0491 0.0931 0.7742
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 797 276 image if available 3081 14857 257.1 73.60 95.99 124.19 175 187 202 218 241 266 296 325 367 0.0703 1045 0.709 60.54 16.03 2 0.0568 175 0.0097 3.01 5.047 0.5308 71538.3
21500000
6880000000
2330000000000
0.3683 0.2682 0.0023 0.0000 0.0053 0.0000 0.0107 0.0015 0.0328 0.0041 0.0710 0.0354 0.1154 0.0479 0.1054 0.0420 0.1398 0.0593 0.5172 0.8099 0.0014 0.0000 0.0019 0.0000 0.0043 0.0007 0.0125 0.0013 0.0288 0.0202 0.0389 0.0276 0.0408 0.0189 0.0504 0.0315 0.8209 0.8998 0.0013 0.0000 0.0000 0.0111 0.0090 0.0028 0.0168 0.0306 0.0530 0.0889 0.0917 0.1306 0.0646 0.1139 0.0904 0.1500 0.6731 0.4722 0.0015 0.0015 0.0052 0.0126 0.0238 0.0535 0.0416 0.0558 0.8045 12 19 29 42 54 70 95 135 230 0.0663 4.54 3.869 0.7237 24635.6
11400000
7270000000
5520000000000
0.4425 0.1810 0.0092 0.0039 0.0252 0.0102 0.0406 0.0158 0.0729 0.0304 0.1237 0.0621 0.1566 0.0900 0.1494 0.0954 0.1869 0.1280 0.2356 0.5641 0.0025 0.0017 0.0033 0.0049 0.0040 0.0052 0.0113 0.0100 0.0302 0.0240 0.0458 0.0344 0.0473 0.0408 0.0691 0.0611 0.7864 0.8179 0.0008 0.0007 0.0034 0.0027 0.0059 0.0050 0.0163 0.0174 0.0487 0.0557 0.0704 0.0795 0.0637 0.0651 0.0789 0.0849 0.7118 0.6890 0.0011 0.0052 0.0059 0.0142 0.0363 0.0542 0.0582 0.0716 0.7533
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 164 879 image if available 4050 8872 419.4 110.73 86.10 234.18 295 334 362 385 409 439 474 515 570 0.0979 869 0.960 155.00 54.01 3 0.1049 425 0.0007 76.29 7.489 0.1602 188142.0
89200000
44400000000
23100000000000
0.4137 0.2255 0.0004 0.0000 0.0017 0.0000 0.0052 0.0000 0.0231 0.0043 0.0718 0.0210 0.1144 0.0459 0.1271 0.0397 0.1462 0.0559 0.5100 0.8333 0.0003 0.0000 0.0006 0.0000 0.0019 0.0000 0.0071 0.0013 0.0298 0.0149 0.0481 0.0238 0.0528 0.0149 0.0708 0.0245 0.7886 0.9206 0.0011 0.0000 0.0043 0.0099 0.0130 0.0099 0.0444 0.0759 0.0704 0.1452 0.1083 0.1716 0.0986 0.1089 0.1073 0.1584 0.5525 0.3201 0.0016 0.0032 0.0111 0.0185 0.0506 0.0749 0.0611 0.0870 0.6921 11 12 14 15 16 17 20 35 226 0.4982 14.49 2.220 0.8059 62249.3
81200000
135000000000
258000000000000
0.6303 0.0763 0.2131 0.0132 0.4262 0.1376 0.2295 0.3995 0.0546 0.1508 0.0546 0.1164 0.0219 0.1085 0.0000 0.0423 0.0000 0.0265 0.0000 0.0053 0.0007 0.0006 0.0055 0.0019 0.0097 0.0070 0.0194 0.0171 0.0947 0.0912 0.1418 0.1476 0.0705 0.0646 0.0961 0.0956 0.5615 0.5744 0.0008 0.0008 0.0032 0.0042 0.0071 0.0100 0.0301 0.0308 0.1013 0.1032 0.1362 0.1424 0.0831 0.0849 0.1077 0.1091 0.5305 0.5146 0.0022 0.0037 0.0066 0.0176 0.1051 0.1412 0.0713 0.1037 0.5485
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1041 916 image if available 403 1181 80.5 10.16 173.50 253.63 67 70 74 77 80 84 86 90 94 0.2320 274 1.030 30.08 8.00 0 0.1762 71 0.1226 0.50 2.391 0.7876 6578.3
546175
46000000
3940000000
0.3807 0.2394 0.0000 0.0000 0.0000 0.0000 0.0054 0.0000 0.0188 0.0124 0.0591 0.0422 0.1237 0.1166 0.1022 0.0422 0.1532 0.0794 0.5376 0.7072 0.0000 0.0000 0.0000 0.0000 0.0025 0.0000 0.0176 0.0124 0.0403 0.0422 0.1159 0.1166 0.0554 0.0422 0.0781 0.0794 0.6902 0.7072 0.0800 0.0000 0.0800 0.0000 0.0000 0.0000 0.2000 0.0000 0.1200 0.0000 0.0800 0.0000 0.2000 0.0000 0.2000 0.0000 0.0400 0.0000 0.0048 0.0000 0.0144 0.0383 0.1005 0.1340 0.0861 0.1627 0.4593 19 27 36 48 66 100 161 254 474 0.0380 54.53 4.632 0.4971 94375.3
84600000
95200000000
121000000000000
0.4414 0.1907 0.1038 0.0045 0.2264 0.0588 0.2170 0.1810 0.0472 0.1267 0.1415 0.2262 0.1321 0.1765 0.0943 0.0679 0.0189 0.0498 0.0189 0.1086 0.0000 0.0000 0.0026 0.0021 0.0026 0.0043 0.0490 0.0322 0.1108 0.1052 0.2010 0.1824 0.1031 0.0966 0.1237 0.1223 0.4072 0.4549 0.0035 0.0041 0.0142 0.0122 0.0284 0.0245 0.0674 0.0531 0.1418 0.1633 0.1596 0.1633 0.0887 0.0939 0.1348 0.1347 0.3617 0.3510 0.0030 0.0030 0.0119 0.0625 0.1310 0.1964 0.0923 0.1190 0.3810
MCF 10A Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 1243 854 image if available 722 7966 63.7 17.26 99.18 192.37 47 51 53 56 60 63 68 74 85 0.0734 585 0.421 183.11 37.80 0 0.8726 630 0.0093 10.56 5.018 0.3434 4360.7
324711
26600000
2420000000
0.4665 0.1732 0.0048 0.0000 0.0238 0.0000 0.0499 0.0060 0.0950 0.0255 0.1354 0.0510 0.1853 0.0990 0.1663 0.1049 0.1663 0.1094 0.1734 0.6042 0.0000 0.0000 0.0073 0.0000 0.0128 0.0028 0.0475 0.0097 0.0786 0.0444 0.1408 0.0819 0.1261 0.0611 0.1481 0.0833 0.4388 0.7167 0.0000 0.0000 0.0317 0.0377 0.0159 0.0755 0.0952 0.0755 0.1825 0.3019 0.1825 0.1321 0.1508 0.0566 0.1508 0.2075 0.1905 0.1132 0.0036 0.0180 0.0288 0.0791 0.1259 0.1691 0.1295 0.1511 0.2950 10 12 14 15 17 19 31 113 371 0.1151 73.14 4.084 0.5429 46837.2
32700000
27500000000
26300000000000
0.6007 0.1115 0.2664 0.0211 0.4953 0.1607 0.2103 0.5011 0.0280 0.1882 0.0000 0.0782 0.0000 0.0338 0.0000 0.0127 0.0000 0.0042 0.0000 0.0000 0.0006 0.0005 0.0022 0.0015 0.0056 0.0036 0.0185 0.0247 0.0888 0.0781 0.1355 0.1183 0.0748 0.0848 0.1231 0.1177 0.5509 0.5707 0.0006 0.0007 0.0013 0.0041 0.0083 0.0082 0.0230 0.0211 0.0856 0.0958 0.1540 0.1501 0.0818 0.0795 0.1176 0.1291 0.5278 0.5115 0.0012 0.0024 0.0054 0.0198 0.0929 0.1360 0.0827 0.1210 0.5386
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1130 460 image if available 653 578 83.3 9.22 65.56 101.38 71 74 78 80 83 86 89 92 95 0.3910 226 0.478 77.79 11.31 1 0.3155 206 0.1159 0.55 2.394 0.7678 7017.7
598559
51600000
4510000000
0.4222 0.2132 0.0000 0.0000 0.0000 0.0000 0.0032 0.0000 0.0065 0.0015 0.0455 0.0352 0.0698 0.0674 0.0779 0.0260 0.1347 0.0475 0.6623 0.8224 0.0000 0.0000 0.0000 0.0000 0.0031 0.0000 0.0047 0.0015 0.0376 0.0352 0.0610 0.0674 0.0297 0.0260 0.0563 0.0475 0.8075 0.8224 0.1304 0.0000 0.3478 0.0000 0.2174 0.0000 0.1304 0.0000 0.0870 0.0000 0.0435 0.0000 0.0435 0.0000 0.0000 0.0000 0.0000 0.0000 0.0030 0.0151 0.0211 0.0452 0.0994 0.0964 0.1325 0.1687 0.4187 7 10 13 18 24 35 52 90 200 0.0809 31.27 3.431 0.5091 14559.2
5410000
2520000000
1320000000000
0.5610 0.0846 0.2727 0.0094 0.5000 0.0377 0.2273 0.4151 0.0000 0.3396 0.0000 0.1038 0.0000 0.0849 0.0000 0.0094 0.0000 0.0000 0.0000 0.0000 0.0000 0.0046 0.0405 0.0091 0.0173 0.0274 0.0347 0.0365 0.2023 0.1507 0.3410 0.3196 0.1676 0.1553 0.1850 0.1918 0.0116 0.1050 0.0155 0.0177 0.0233 0.0265 0.0698 0.0885 0.0853 0.0619 0.2636 0.3894 0.3488 0.3009 0.1860 0.1150 0.0078 0.0000 0.0000 0.0000 0.0134 0.0201 0.0336 0.0336 0.2282 0.3758 0.2013 0.0940 0.0000