High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1028 | 672 | | 465 | 2154 | 115.4 | 21.95 | 94.06 | 88.63 | 88 | 97 | 102 | 107 | 113 | 119 | 127 | 135 | 145 | 0.1467 | 316 | 0.423 | 90.70 | 21.40 | 1 | 0.5978 | 278 | 0.0052 | 16.34 | 5.463 | 0.2803 | 13796.9 | 1710000 | 218000000 | 28800000000 | 0.4162 | 0.2196 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0247 | 0.0022 | 0.0556 | 0.0111 | 0.1049 | 0.0509 | 0.1852 | 0.0907 | 0.1420 | 0.0575 | 0.1821 | 0.1062 | 0.3025 | 0.6814 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0273 | 0.0086 | 0.0695 | 0.0452 | 0.1042 | 0.0839 | 0.0720 | 0.0344 | 0.1117 | 0.0796 | 0.6104 | 0.7462 | 0.0000 | 0.0000 | 0.0380 | 0.1538 | 0.0380 | 0.0000 | 0.1139 | 0.1538 | 0.1519 | 0.3846 | 0.2152 | 0.0000 | 0.1392 | 0.1538 | 0.1139 | 0.1538 | 0.1899 | 0.0000 | 0.0000 | 0.0045 | 0.0179 | 0.0538 | 0.1345 | 0.1211 | 0.1211 | 0.1704 | 0.3767 | 17 | 26 | 35 | 44 | 58 | 78 | 107 | 164 | 229 | 0.0192 | 12.21 | 4.935 | 0.4816 | 16699.0 | 4090000 | 1190000000 | 384000000000 | 0.5433 | 0.1288 | 0.0185 | 0.0036 | 0.1218 | 0.0145 | 0.1808 | 0.0416 | 0.1734 | 0.1139 | 0.2251 | 0.1953 | 0.0959 | 0.1664 | 0.0812 | 0.1356 | 0.0554 | 0.1447 | 0.0480 | 0.1844 | 0.0000 | 0.0000 | 0.0056 | 0.0009 | 0.0090 | 0.0027 | 0.0124 | 0.0192 | 0.0710 | 0.0602 | 0.1150 | 0.0794 | 0.0744 | 0.0776 | 0.1488 | 0.1487 | 0.5637 | 0.6113 | 0.0016 | 0.0000 | 0.0032 | 0.0018 | 0.0065 | 0.0147 | 0.0260 | 0.0313 | 0.0666 | 0.0792 | 0.1380 | 0.1455 | 0.0893 | 0.0958 | 0.1347 | 0.1602 | 0.5341 | 0.4715 | 0.0014 | 0.0082 | 0.0109 | 0.0301 | 0.0657 | 0.1012 | 0.0821 | 0.1477 | 0.5527 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 630 | 725 | | 3602 | 12705 | 123.5 | 28.89 | 207.97 | 184.41 | 91 | 99 | 107 | 113 | 120 | 127 | 135 | 145 | 162 | 0.0653 | 830 | 0.652 | 114.81 | 32.25 | 2 | 0.0999 | 360 | 0.0026 | 19.30 | 6.264 | 0.2653 | 16090.9 | 2210000 | 321000000 | 49000000000 | 0.4640 | 0.1807 | 0.0004 | 0.0000 | 0.0022 | 0.0000 | 0.0089 | 0.0003 | 0.0289 | 0.0036 | 0.1061 | 0.0245 | 0.1488 | 0.0660 | 0.1710 | 0.0554 | 0.1856 | 0.0845 | 0.3481 | 0.7657 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0000 | 0.0104 | 0.0020 | 0.0494 | 0.0165 | 0.0841 | 0.0414 | 0.0838 | 0.0255 | 0.1088 | 0.0448 | 0.6587 | 0.8698 | 0.0048 | 0.0136 | 0.0144 | 0.0317 | 0.0256 | 0.0226 | 0.0832 | 0.1448 | 0.1344 | 0.1584 | 0.1648 | 0.2579 | 0.1328 | 0.1041 | 0.1360 | 0.1176 | 0.3040 | 0.1493 | 0.0019 | 0.0080 | 0.0161 | 0.0427 | 0.0860 | 0.1373 | 0.1132 | 0.1429 | 0.4521 | 17 | 41 | 80 | 122 | 166 | 214 | 273 | 344 | 450 | 0.0066 | 49.93 | 6.596 | 0.3005 | 77256.1 | 39900000 | 27300000000 | 24000000000000 | 0.5228 | 0.1478 | 0.0366 | 0.0017 | 0.1741 | 0.0093 | 0.2322 | 0.0745 | 0.1644 | 0.1242 | 0.1732 | 0.1875 | 0.1185 | 0.1933 | 0.0585 | 0.1480 | 0.0307 | 0.1381 | 0.0117 | 0.1234 | 0.0005 | 0.0001 | 0.0017 | 0.0009 | 0.0038 | 0.0032 | 0.0202 | 0.0107 | 0.0760 | 0.0570 | 0.1225 | 0.1019 | 0.0993 | 0.0819 | 0.1496 | 0.1250 | 0.5266 | 0.6193 | 0.0012 | 0.0014 | 0.0023 | 0.0064 | 0.0098 | 0.0188 | 0.0393 | 0.0507 | 0.1129 | 0.1298 | 0.1665 | 0.1799 | 0.1234 | 0.1272 | 0.1737 | 0.1599 | 0.3709 | 0.3259 | 0.0010 | 0.0040 | 0.0082 | 0.0276 | 0.0888 | 0.1485 | 0.1189 | 0.1654 | 0.4377 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 331 | 718 | | 6517 | 14109 | 121.3 | 38.02 | 212.08 | 139.30 | 76 | 89 | 98 | 106 | 116 | 126 | 139 | 154 | 173 | 0.0670 | 946 | 0.522 | 141.32 | 34.66 | 1 | 0.0758 | 494 | 0.0017 | 23.72 | 6.654 | 0.2362 | 16163.3 | 2350000 | 371000000 | 63300000000 | 0.4672 | 0.1926 | 0.0013 | 0.0002 | 0.0033 | 0.0000 | 0.0140 | 0.0028 | 0.0447 | 0.0100 | 0.1142 | 0.0351 | 0.1883 | 0.0820 | 0.1596 | 0.0767 | 0.1756 | 0.1199 | 0.2990 | 0.6732 | 0.0004 | 0.0002 | 0.0017 | 0.0000 | 0.0041 | 0.0012 | 0.0137 | 0.0047 | 0.0345 | 0.0203 | 0.0687 | 0.0391 | 0.0668 | 0.0281 | 0.0852 | 0.0555 | 0.7248 | 0.8511 | 0.0006 | 0.0027 | 0.0019 | 0.0190 | 0.0131 | 0.0244 | 0.0473 | 0.0799 | 0.1021 | 0.1721 | 0.1594 | 0.2033 | 0.1152 | 0.1179 | 0.1519 | 0.1518 | 0.4085 | 0.2290 | 0.0014 | 0.0024 | 0.0106 | 0.0294 | 0.0608 | 0.1086 | 0.0820 | 0.1134 | 0.5914 | 42 | 83 | 121 | 156 | 193 | 231 | 273 | 329 | 409 | 0.0025 | 30.32 | 6.672 | 0.2808 | 64379.2 | 23700000 | 9980000000 | 4630000000000 | 0.5768 | 0.1249 | 0.0132 | 0.0007 | 0.0829 | 0.0038 | 0.2244 | 0.0304 | 0.2064 | 0.0794 | 0.1855 | 0.1514 | 0.1565 | 0.2137 | 0.0868 | 0.1808 | 0.0344 | 0.1635 | 0.0100 | 0.1763 | 0.0005 | 0.0000 | 0.0010 | 0.0005 | 0.0062 | 0.0022 | 0.0221 | 0.0124 | 0.0612 | 0.0460 | 0.1242 | 0.0904 | 0.0972 | 0.0798 | 0.1246 | 0.1106 | 0.5630 | 0.6581 | 0.0029 | 0.0020 | 0.0062 | 0.0061 | 0.0179 | 0.0276 | 0.0458 | 0.0711 | 0.1142 | 0.1294 | 0.1552 | 0.1673 | 0.1257 | 0.1207 | 0.1490 | 0.1595 | 0.3830 | 0.3164 | 0.0008 | 0.0041 | 0.0099 | 0.0341 | 0.0887 | 0.1328 | 0.1162 | 0.1460 | 0.4674 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 418 | 234 | | 17233 | 30716 | 142.7 | 48.74 | 171.07 | 136.88 | 91 | 103 | 113 | 123 | 134 | 146 | 159 | 179 | 208 | 0.0589 | 1808 | 0.875 | 171.23 | 50.54 | 6 | 0.0257 | 443 | 0.0012 | 32.99 | 7.078 | 0.2149 | 22747.1 | 4030000 | 792000000 | 170000000000 | 0.4209 | 0.2369 | 0.0013 | 0.0001 | 0.0039 | 0.0003 | 0.0174 | 0.0014 | 0.0505 | 0.0050 | 0.1309 | 0.0315 | 0.1949 | 0.0683 | 0.1734 | 0.0758 | 0.1834 | 0.1141 | 0.2444 | 0.7035 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0058 | 0.0006 | 0.0141 | 0.0022 | 0.0490 | 0.0156 | 0.0844 | 0.0320 | 0.0765 | 0.0347 | 0.0991 | 0.0569 | 0.6692 | 0.8578 | 0.0040 | 0.0044 | 0.0055 | 0.0098 | 0.0144 | 0.0186 | 0.0431 | 0.0667 | 0.1096 | 0.1382 | 0.1445 | 0.1770 | 0.1086 | 0.1078 | 0.1442 | 0.1436 | 0.4260 | 0.3338 | 0.0011 | 0.0020 | 0.0089 | 0.0326 | 0.0833 | 0.1183 | 0.0961 | 0.1280 | 0.5296 | 21 | 42 | 74 | 109 | 144 | 182 | 223 | 278 | 356 | 0.0059 | 37.42 | 6.647 | 0.3123 | 47999.4 | 17500000 | 7750000000 | 3980000000000 | 0.5887 | 0.1133 | 0.0187 | 0.0011 | 0.0941 | 0.0056 | 0.1941 | 0.0281 | 0.1770 | 0.0790 | 0.1770 | 0.1591 | 0.1489 | 0.1991 | 0.0907 | 0.1550 | 0.0639 | 0.1574 | 0.0358 | 0.2154 | 0.0003 | 0.0001 | 0.0018 | 0.0009 | 0.0044 | 0.0024 | 0.0138 | 0.0084 | 0.0576 | 0.0421 | 0.1092 | 0.0858 | 0.0878 | 0.0696 | 0.1288 | 0.1035 | 0.5963 | 0.6873 | 0.0013 | 0.0017 | 0.0050 | 0.0076 | 0.0119 | 0.0155 | 0.0341 | 0.0397 | 0.0958 | 0.1103 | 0.1473 | 0.1630 | 0.1089 | 0.1127 | 0.1449 | 0.1590 | 0.4508 | 0.3906 | 0.0007 | 0.0032 | 0.0079 | 0.0194 | 0.0783 | 0.1344 | 0.1013 | 0.1353 | 0.5195 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1055 | 344 | | 487 | 5051 | 49.0 | 12.36 | 116.43 | 167.87 | 32 | 38 | 43 | 46 | 49 | 52 | 55 | 59 | 65 | 0.0810 | 409 | 1.242 | 45.35 | 19.21 | 2 | 0.2485 | 121 | 0.0057 | 11.72 | 5.356 | 0.3095 | 2555.8 | 140162 | 8020000 | 475000000 | 0.4385 | 0.1798 | 0.0000 | 0.0000 | 0.0075 | 0.0000 | 0.0522 | 0.0000 | 0.1045 | 0.0189 | 0.1604 | 0.0731 | 0.1604 | 0.0967 | 0.1642 | 0.1250 | 0.1604 | 0.1627 | 0.1903 | 0.5236 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0293 | 0.0177 | 0.0745 | 0.0576 | 0.0931 | 0.0665 | 0.1356 | 0.0687 | 0.1330 | 0.1020 | 0.5319 | 0.6874 | 0.0093 | 0.0370 | 0.0278 | 0.1111 | 0.0185 | 0.1481 | 0.1574 | 0.1852 | 0.1296 | 0.2222 | 0.2130 | 0.1481 | 0.1481 | 0.1111 | 0.1389 | 0.0000 | 0.1574 | 0.0370 | 0.0000 | 0.0000 | 0.0038 | 0.0651 | 0.1149 | 0.1609 | 0.1686 | 0.1801 | 0.3065 | 21 | 24 | 27 | 33 | 48 | 74 | 108 | 161 | 274 | 0.0561 | 13.35 | 4.308 | 0.5688 | 41728.7 | 26200000 | 21000000000 | 19200000000000 | 0.6628 | 0.0772 | 0.0483 | 0.0009 | 0.1324 | 0.0250 | 0.1843 | 0.1026 | 0.1395 | 0.1100 | 0.1467 | 0.1590 | 0.1521 | 0.1654 | 0.0912 | 0.1451 | 0.0644 | 0.1146 | 0.0411 | 0.1774 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0035 | 0.0029 | 0.0260 | 0.0211 | 0.0860 | 0.0694 | 0.1166 | 0.0991 | 0.0912 | 0.0804 | 0.1396 | 0.1197 | 0.5361 | 0.6060 | 0.0009 | 0.0000 | 0.0043 | 0.0050 | 0.0068 | 0.0099 | 0.0324 | 0.0417 | 0.1107 | 0.1202 | 0.1388 | 0.1400 | 0.0894 | 0.1043 | 0.1516 | 0.1589 | 0.4651 | 0.4201 | 0.0014 | 0.0007 | 0.0085 | 0.0318 | 0.1108 | 0.1200 | 0.0924 | 0.1623 | 0.4721 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 701 | 317 | | 1010 | 1709 | 117.2 | 14.08 | 14.40 | 13.12 | 99 | 104 | 109 | 112 | 117 | 120 | 125 | 130 | 137 | 0.2264 | 387 | 0.804 | 89.94 | 22.63 | 3 | 0.2515 | 254 | 0.0285 | 1.46 | 3.784 | 0.5971 | 13944.3 | 1680000 | 206000000 | 25500000000 | 0.4094 | 0.2171 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0173 | 0.0079 | 0.0539 | 0.0366 | 0.0949 | 0.0772 | 0.0949 | 0.0475 | 0.1284 | 0.0554 | 0.6063 | 0.7743 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0031 | 0.0010 | 0.0153 | 0.0079 | 0.0408 | 0.0366 | 0.0704 | 0.0772 | 0.0551 | 0.0475 | 0.0643 | 0.0554 | 0.7500 | 0.7743 | 0.0755 | 0.0000 | 0.0566 | 0.0000 | 0.0755 | 0.0000 | 0.3019 | 0.0000 | 0.1509 | 0.0000 | 0.1698 | 0.0000 | 0.0566 | 0.0000 | 0.0755 | 0.0000 | 0.0377 | 0.0000 | 0.0000 | 0.0119 | 0.0119 | 0.0356 | 0.0652 | 0.1047 | 0.1126 | 0.1285 | 0.5296 | 6 | 7 | 8 | 9 | 10 | 12 | 14 | 18 | 27 | 0.2146 | 0.58 | 2.293 | 0.8004 | 379.5 | 17210.3 | 1060000 | 75400000 | 0.6023 | 0.1002 | 0.1389 | 0.0185 | 0.1528 | 0.0420 | 0.1910 | 0.0791 | 0.2014 | 0.1471 | 0.1632 | 0.1483 | 0.0868 | 0.1508 | 0.0417 | 0.1434 | 0.0243 | 0.1434 | 0.0000 | 0.1273 | 0.0532 | 0.0116 | 0.0388 | 0.0268 | 0.0403 | 0.0528 | 0.0446 | 0.0966 | 0.0935 | 0.1109 | 0.1410 | 0.1270 | 0.0777 | 0.1064 | 0.1410 | 0.1145 | 0.3698 | 0.3533 | 0.0197 | 0.0032 | 0.0221 | 0.0194 | 0.0246 | 0.0227 | 0.0491 | 0.0680 | 0.1302 | 0.1262 | 0.1474 | 0.1780 | 0.1179 | 0.1197 | 0.1843 | 0.1586 | 0.3047 | 0.3042 | 0.0209 | 0.0209 | 0.0342 | 0.0512 | 0.0892 | 0.1518 | 0.0854 | 0.1613 | 0.3852 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1162 | 503 | | 2529 | 2344 | 126.3 | 43.34 | 188.90 | 122.03 | 73 | 88 | 100 | 110 | 122 | 133 | 145 | 162 | 185 | 0.1950 | 457 | 0.720 | 84.38 | 20.03 | 1 | 0.0834 | 211 | 0.0009 | 89.32 | 7.225 | 0.1409 | 17828.9 | 2770000 | 469000000 | 85100000000 | 0.4531 | 0.1879 | 0.0000 | 0.0000 | 0.0045 | 0.0021 | 0.0334 | 0.0032 | 0.0885 | 0.0117 | 0.1554 | 0.0573 | 0.2069 | 0.1183 | 0.1527 | 0.1210 | 0.1509 | 0.1666 | 0.2078 | 0.5199 | 0.0000 | 0.0000 | 0.0006 | 0.0013 | 0.0023 | 0.0018 | 0.0153 | 0.0081 | 0.0512 | 0.0346 | 0.0904 | 0.0606 | 0.0745 | 0.0454 | 0.0944 | 0.0718 | 0.6714 | 0.7764 | 0.0031 | 0.0088 | 0.0077 | 0.0263 | 0.0153 | 0.0351 | 0.0537 | 0.0906 | 0.1503 | 0.1579 | 0.1656 | 0.1813 | 0.1012 | 0.0906 | 0.1518 | 0.1579 | 0.3512 | 0.2515 | 0.0000 | 0.0009 | 0.0043 | 0.0282 | 0.1059 | 0.1443 | 0.1059 | 0.1460 | 0.4646 | 57 | 75 | 104 | 135 | 169 | 201 | 239 | 281 | 355 | 0.0049 | 19.35 | 5.900 | 0.3617 | 50569.7 | 17000000 | 6670000000 | 2960000000000 | 0.5121 | 0.1476 | 0.0119 | 0.0010 | 0.0889 | 0.0089 | 0.1976 | 0.0207 | 0.1621 | 0.0720 | 0.1581 | 0.1519 | 0.1561 | 0.2002 | 0.0870 | 0.1322 | 0.0870 | 0.1686 | 0.0514 | 0.2446 | 0.0000 | 0.0006 | 0.0008 | 0.0006 | 0.0093 | 0.0025 | 0.0202 | 0.0153 | 0.0644 | 0.0567 | 0.1149 | 0.0943 | 0.0901 | 0.0732 | 0.1335 | 0.1115 | 0.5668 | 0.6452 | 0.0013 | 0.0090 | 0.0064 | 0.0162 | 0.0153 | 0.0252 | 0.0435 | 0.0629 | 0.1228 | 0.1457 | 0.1662 | 0.1853 | 0.1368 | 0.1097 | 0.1675 | 0.1583 | 0.3402 | 0.2878 | 0.0000 | 0.0019 | 0.0135 | 0.0348 | 0.0890 | 0.1277 | 0.1180 | 0.1750 | 0.4400 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1035 | 628 | | 3458 | 8206 | 93.8 | 23.90 | 164.82 | 119.42 | 66 | 74 | 79 | 85 | 91 | 97 | 104 | 113 | 127 | 0.1078 | 885 | 0.355 | 97.08 | 18.11 | 4 | 0.0992 | 343 | 0.0017 | 31.62 | 6.627 | 0.2197 | 9369.6 | 995442 | 112000000 | 13400000000 | 0.5072 | 0.1581 | 0.0015 | 0.0000 | 0.0041 | 0.0003 | 0.0193 | 0.0026 | 0.0491 | 0.0078 | 0.1120 | 0.0342 | 0.1621 | 0.0785 | 0.1682 | 0.0691 | 0.1778 | 0.1092 | 0.3060 | 0.6983 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0049 | 0.0006 | 0.0154 | 0.0030 | 0.0566 | 0.0245 | 0.0779 | 0.0558 | 0.0738 | 0.0349 | 0.1124 | 0.0626 | 0.6576 | 0.8187 | 0.0000 | 0.0233 | 0.0158 | 0.0117 | 0.0288 | 0.0623 | 0.0806 | 0.1440 | 0.1568 | 0.1673 | 0.1683 | 0.1479 | 0.1094 | 0.1012 | 0.1540 | 0.1206 | 0.2863 | 0.2218 | 0.0013 | 0.0064 | 0.0160 | 0.0415 | 0.0958 | 0.1213 | 0.1232 | 0.1430 | 0.4515 | 25 | 62 | 87 | 112 | 142 | 175 | 210 | 257 | 327 | 0.0060 | 20.13 | 5.985 | 0.3796 | 41426.6 | 13400000 | 5300000000 | 2470000000000 | 0.5023 | 0.1523 | 0.0128 | 0.0015 | 0.0745 | 0.0055 | 0.1680 | 0.0312 | 0.1607 | 0.0802 | 0.1796 | 0.1311 | 0.1362 | 0.1697 | 0.1057 | 0.1489 | 0.0910 | 0.1507 | 0.0715 | 0.2812 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0048 | 0.0030 | 0.0166 | 0.0153 | 0.0547 | 0.0413 | 0.1021 | 0.0745 | 0.0780 | 0.0668 | 0.1117 | 0.0947 | 0.6316 | 0.7023 | 0.0011 | 0.0014 | 0.0047 | 0.0048 | 0.0131 | 0.0106 | 0.0367 | 0.0476 | 0.0956 | 0.1264 | 0.1425 | 0.1563 | 0.1142 | 0.1317 | 0.1455 | 0.1582 | 0.4465 | 0.3630 | 0.0000 | 0.0011 | 0.0056 | 0.0240 | 0.0760 | 0.1185 | 0.0978 | 0.1440 | 0.5328 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 387 | 777 | | 3566 | 6931 | 639.4 | 107.04 | 10.06 | 4.66 | 486 | 547 | 588 | 620 | 651 | 674 | 700 | 732 | 773 | 0.0884 | 613 | 1.124 | 98.72 | 31.38 | 1 | 0.0670 | 239 | 0.0010 | 36.61 | 7.121 | 0.1989 | 420338.0 | 283000000 | 195000000000 | 137000000000000 | 0.3984 | 0.2382 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0000 | 0.0083 | 0.0003 | 0.0320 | 0.0164 | 0.0531 | 0.0288 | 0.0531 | 0.0164 | 0.0753 | 0.0257 | 0.7708 | 0.9124 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0003 | 0.0186 | 0.0158 | 0.0258 | 0.0270 | 0.0225 | 0.0141 | 0.0287 | 0.0217 | 0.9000 | 0.9211 | 0.0000 | 0.0000 | 0.0149 | 0.1667 | 0.0446 | 0.0833 | 0.0718 | 0.2500 | 0.0767 | 0.2500 | 0.1287 | 0.2500 | 0.0965 | 0.0000 | 0.1658 | 0.0000 | 0.4010 | 0.0000 | 0.0010 | 0.0005 | 0.0021 | 0.0124 | 0.0361 | 0.0465 | 0.0589 | 0.0780 | 0.7646 | 5 | 7 | 7 | 8 | 9 | 10 | 12 | 13 | 16 | 0.4127 | 0.30 | 1.079 | 0.7896 | 122.9 | 1790.87 | 30353.2 | 582290 | 0.5361 | 0.1291 | 0.0335 | 0.0045 | 0.0959 | 0.0139 | 0.1633 | 0.0252 | 0.2000 | 0.0536 | 0.2138 | 0.0902 | 0.1661 | 0.1532 | 0.0951 | 0.2086 | 0.0264 | 0.2648 | 0.0059 | 0.1859 | 0.0097 | 0.0003 | 0.0311 | 0.0027 | 0.0593 | 0.0058 | 0.0757 | 0.0236 | 0.0929 | 0.0587 | 0.1048 | 0.1040 | 0.1018 | 0.1321 | 0.1193 | 0.1860 | 0.4054 | 0.4869 | 0.0652 | 0.0615 | 0.0666 | 0.0608 | 0.0576 | 0.0615 | 0.0566 | 0.0660 | 0.0756 | 0.0801 | 0.0809 | 0.1008 | 0.0856 | 0.1127 | 0.1365 | 0.1579 | 0.3754 | 0.2987 | 0.0501 | 0.0714 | 0.0772 | 0.0740 | 0.0778 | 0.0730 | 0.0804 | 0.1126 | 0.3836 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 307 | 653 | | 10385 | 21337 | 574.1 | 114.46 | 155.18 | 135.73 | 433 | 473 | 505 | 535 | 564 | 596 | 628 | 670 | 733 | 0.0486 | 1036 | 0.577 | 103.02 | 13.04 | 1 | 0.0206 | 214 | 0.0007 | 50.52 | 7.494 | 0.1652 | 342696.0 | 212000000 | 136000000000 | 90600000000000 | 0.4477 | 0.1993 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0000 | 0.0114 | 0.0003 | 0.0529 | 0.0143 | 0.1183 | 0.0275 | 0.1255 | 0.0275 | 0.1535 | 0.0489 | 0.5362 | 0.8814 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0053 | 0.0001 | 0.0241 | 0.0099 | 0.0493 | 0.0168 | 0.0533 | 0.0122 | 0.0720 | 0.0203 | 0.7946 | 0.9407 | 0.0023 | 0.0176 | 0.0082 | 0.0265 | 0.0164 | 0.0676 | 0.0614 | 0.1088 | 0.1392 | 0.2118 | 0.1766 | 0.2000 | 0.1094 | 0.1294 | 0.1433 | 0.1235 | 0.3433 | 0.1147 | 0.0008 | 0.0010 | 0.0049 | 0.0246 | 0.0722 | 0.1181 | 0.0958 | 0.1311 | 0.5515 | 25 | 42 | 64 | 88 | 118 | 150 | 191 | 249 | 337 | 0.0077 | 23.32 | 5.939 | 0.3643 | 42503.4 | 16400000 | 8080000000 | 4790000000000 | 0.5282 | 0.1429 | 0.0347 | 0.0014 | 0.1391 | 0.0079 | 0.2389 | 0.0792 | 0.1810 | 0.1231 | 0.1607 | 0.1736 | 0.1170 | 0.1882 | 0.0714 | 0.1466 | 0.0353 | 0.1335 | 0.0219 | 0.1463 | 0.0005 | 0.0002 | 0.0011 | 0.0004 | 0.0042 | 0.0024 | 0.0233 | 0.0140 | 0.0793 | 0.0638 | 0.1263 | 0.0985 | 0.1017 | 0.0802 | 0.1398 | 0.1307 | 0.5240 | 0.6098 | 0.0009 | 0.0039 | 0.0053 | 0.0039 | 0.0117 | 0.0141 | 0.0449 | 0.0589 | 0.1098 | 0.1287 | 0.1665 | 0.1769 | 0.1228 | 0.1268 | 0.1550 | 0.1577 | 0.3832 | 0.3291 | 0.0010 | 0.0024 | 0.0071 | 0.0342 | 0.0973 | 0.1484 | 0.1159 | 0.1555 | 0.4382 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 989 | 569 | | 11363 | 17154 | 435.1 | 102.14 | 100.15 | 106.92 | 319 | 350 | 374 | 396 | 420 | 445 | 475 | 519 | 577 | 0.0642 | 1102 | 1.214 | 111.97 | 45.88 | 1 | 0.0259 | 294 | 0.0008 | 45.10 | 7.457 | 0.1791 | 199761.0 | 96800000 | 49400000000 | 26500000000000 | 0.4356 | 0.2162 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0049 | 0.0006 | 0.0187 | 0.0024 | 0.0547 | 0.0168 | 0.1228 | 0.0359 | 0.1224 | 0.0361 | 0.1532 | 0.0537 | 0.5207 | 0.8544 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0001 | 0.0074 | 0.0009 | 0.0262 | 0.0104 | 0.0589 | 0.0186 | 0.0605 | 0.0168 | 0.0788 | 0.0275 | 0.7659 | 0.9258 | 0.0027 | 0.0014 | 0.0063 | 0.0068 | 0.0094 | 0.0315 | 0.0367 | 0.0876 | 0.0823 | 0.1231 | 0.1360 | 0.1737 | 0.0922 | 0.1081 | 0.1128 | 0.1231 | 0.5217 | 0.3447 | 0.0010 | 0.0012 | 0.0068 | 0.0319 | 0.0806 | 0.1097 | 0.0930 | 0.1123 | 0.5635 | 7 | 11 | 20 | 37 | 62 | 94 | 132 | 180 | 248 | 0.0392 | 11.55 | 4.988 | 0.4732 | 21460.8 | 6340000 | 2300000000 | 971000000000 | 0.5515 | 0.1124 | 0.0581 | 0.0039 | 0.2164 | 0.0200 | 0.2885 | 0.1377 | 0.1593 | 0.1383 | 0.1259 | 0.1997 | 0.0867 | 0.1917 | 0.0344 | 0.1180 | 0.0237 | 0.1032 | 0.0070 | 0.0874 | 0.0001 | 0.0001 | 0.0005 | 0.0005 | 0.0012 | 0.0003 | 0.0130 | 0.0092 | 0.0667 | 0.0520 | 0.1087 | 0.0943 | 0.0812 | 0.0656 | 0.1186 | 0.1022 | 0.6099 | 0.6759 | 0.0005 | 0.0012 | 0.0010 | 0.0029 | 0.0045 | 0.0074 | 0.0218 | 0.0286 | 0.0939 | 0.1036 | 0.1590 | 0.1785 | 0.0997 | 0.1088 | 0.1431 | 0.1573 | 0.4763 | 0.4118 | 0.0003 | 0.0006 | 0.0018 | 0.0174 | 0.0781 | 0.1316 | 0.0944 | 0.1376 | 0.5381 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 991 | 744 | | 5862 | 10539 | 192.1 | 52.46 | 146.42 | 108.37 | 131 | 149 | 162 | 172 | 184 | 197 | 213 | 234 | 265 | 0.0895 | 943 | 0.544 | 198.46 | 47.51 | 3 | 0.0942 | 552 | 0.0009 | 52.02 | 7.253 | 0.1584 | 39655.6 | 8770000 | 2070000000 | 520000000000 | 0.4554 | 0.1871 | 0.0006 | 0.0000 | 0.0034 | 0.0000 | 0.0096 | 0.0008 | 0.0355 | 0.0041 | 0.1058 | 0.0324 | 0.1811 | 0.0725 | 0.1481 | 0.0680 | 0.1700 | 0.0980 | 0.3461 | 0.7242 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0002 | 0.0095 | 0.0011 | 0.0433 | 0.0190 | 0.0801 | 0.0417 | 0.0708 | 0.0310 | 0.1006 | 0.0475 | 0.6930 | 0.8596 | 0.0016 | 0.0115 | 0.0032 | 0.0115 | 0.0206 | 0.0249 | 0.0562 | 0.1109 | 0.1267 | 0.1625 | 0.1544 | 0.2065 | 0.1378 | 0.1013 | 0.1394 | 0.1415 | 0.3603 | 0.2294 | 0.0015 | 0.0043 | 0.0081 | 0.0340 | 0.0858 | 0.1291 | 0.1071 | 0.1272 | 0.5029 | 31 | 47 | 66 | 92 | 121 | 155 | 191 | 236 | 300 | 0.0060 | 18.43 | 5.996 | 0.3631 | 33180.2 | 9590000 | 3250000000 | 1230000000000 | 0.4729 | 0.1780 | 0.0201 | 0.0016 | 0.0959 | 0.0049 | 0.2214 | 0.0320 | 0.2086 | 0.0781 | 0.1735 | 0.1676 | 0.1322 | 0.2150 | 0.0786 | 0.1567 | 0.0491 | 0.1594 | 0.0206 | 0.1847 | 0.0000 | 0.0002 | 0.0009 | 0.0011 | 0.0035 | 0.0017 | 0.0153 | 0.0096 | 0.0587 | 0.0403 | 0.0895 | 0.0744 | 0.0784 | 0.0610 | 0.1174 | 0.0937 | 0.6362 | 0.7182 | 0.0008 | 0.0014 | 0.0033 | 0.0090 | 0.0066 | 0.0118 | 0.0303 | 0.0451 | 0.0869 | 0.1121 | 0.1487 | 0.1637 | 0.1189 | 0.1168 | 0.1451 | 0.1569 | 0.4593 | 0.3832 | 0.0009 | 0.0016 | 0.0060 | 0.0218 | 0.0656 | 0.1141 | 0.1038 | 0.1319 | 0.5544 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1033 | 712 | | 5129 | 6293 | 97.3 | 21.87 | 101.52 | 63.35 | 73 | 79 | 84 | 89 | 94 | 99 | 105 | 113 | 127 | 0.1198 | 754 | 1.045 | 82.39 | 32.89 | 1 | 0.0454 | 233 | 0.0050 | 8.89 | 5.676 | 0.3565 | 9951.5 | 1070000 | 122000000 | 14600000000 | 0.4238 | 0.2335 | 0.0015 | 0.0002 | 0.0027 | 0.0006 | 0.0094 | 0.0006 | 0.0277 | 0.0027 | 0.0690 | 0.0239 | 0.1298 | 0.0420 | 0.1351 | 0.0409 | 0.1808 | 0.0709 | 0.4441 | 0.8180 | 0.0009 | 0.0000 | 0.0014 | 0.0002 | 0.0042 | 0.0004 | 0.0117 | 0.0006 | 0.0391 | 0.0163 | 0.0615 | 0.0248 | 0.0667 | 0.0163 | 0.1036 | 0.0330 | 0.7109 | 0.9084 | 0.0057 | 0.0123 | 0.0181 | 0.0370 | 0.0294 | 0.0216 | 0.0611 | 0.0957 | 0.1041 | 0.1698 | 0.1561 | 0.1698 | 0.1210 | 0.1327 | 0.1493 | 0.1481 | 0.3552 | 0.2130 | 0.0022 | 0.0075 | 0.0141 | 0.0435 | 0.0804 | 0.1094 | 0.1094 | 0.1313 | 0.5024 | 30 | 47 | 61 | 73 | 88 | 104 | 126 | 153 | 191 | 0.0033 | 26.60 | 6.249 | 0.2945 | 14318.5 | 2510000 | 508000000 | 114000000000 | 0.5313 | 0.1551 | 0.0099 | 0.0024 | 0.0992 | 0.0097 | 0.1686 | 0.0286 | 0.1523 | 0.0721 | 0.1856 | 0.1352 | 0.1664 | 0.1776 | 0.1126 | 0.1579 | 0.0729 | 0.1655 | 0.0326 | 0.2510 | 0.0006 | 0.0002 | 0.0044 | 0.0016 | 0.0050 | 0.0032 | 0.0174 | 0.0114 | 0.0636 | 0.0473 | 0.1271 | 0.0905 | 0.1043 | 0.0864 | 0.1315 | 0.1093 | 0.5460 | 0.6500 | 0.0010 | 0.0014 | 0.0051 | 0.0095 | 0.0112 | 0.0265 | 0.0446 | 0.0522 | 0.1076 | 0.1255 | 0.1862 | 0.2171 | 0.1476 | 0.1452 | 0.1558 | 0.1567 | 0.3409 | 0.2659 | 0.0019 | 0.0023 | 0.0096 | 0.0266 | 0.0914 | 0.1450 | 0.1226 | 0.1546 | 0.4458 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 948 | 93 | | 6191 | 5411 | 97.2 | 28.78 | 176.56 | 250.57 | 65 | 74 | 81 | 88 | 94 | 101 | 108 | 118 | 134 | 0.1785 | 966 | 0.915 | 160.59 | 50.92 | 3 | 0.0728 | 451 | 0.0012 | 44.43 | 7.019 | 0.1810 | 10281.0 | 1180000 | 147000000 | 20000000000 | 0.4296 | 0.2140 | 0.0006 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0011 | 0.0445 | 0.0080 | 0.1179 | 0.0337 | 0.1765 | 0.0649 | 0.1815 | 0.0792 | 0.1824 | 0.1193 | 0.2744 | 0.6938 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0003 | 0.0120 | 0.0043 | 0.0482 | 0.0193 | 0.0816 | 0.0358 | 0.0819 | 0.0379 | 0.1103 | 0.0573 | 0.6632 | 0.8451 | 0.0046 | 0.0144 | 0.0144 | 0.0341 | 0.0311 | 0.0485 | 0.0971 | 0.0987 | 0.1115 | 0.1813 | 0.1624 | 0.1418 | 0.1252 | 0.0987 | 0.1373 | 0.1275 | 0.3164 | 0.2549 | 0.0028 | 0.0059 | 0.0121 | 0.0385 | 0.0905 | 0.1273 | 0.1099 | 0.1328 | 0.4802 | 19 | 24 | 31 | 44 | 66 | 104 | 177 | 282 | 478 | 0.0405 | 26.68 | 4.951 | 0.5100 | 93949.7 | 80000000 | 85800000000 | 105000000000000 | 0.6057 | 0.0948 | 0.1074 | 0.0033 | 0.2729 | 0.0546 | 0.2550 | 0.2116 | 0.1208 | 0.1860 | 0.1230 | 0.1815 | 0.0582 | 0.1503 | 0.0425 | 0.0846 | 0.0201 | 0.0579 | 0.0000 | 0.0702 | 0.0005 | 0.0005 | 0.0043 | 0.0019 | 0.0086 | 0.0075 | 0.0311 | 0.0230 | 0.1063 | 0.0962 | 0.1283 | 0.1304 | 0.1063 | 0.0863 | 0.1546 | 0.1487 | 0.4600 | 0.5056 | 0.0007 | 0.0016 | 0.0071 | 0.0049 | 0.0127 | 0.0138 | 0.0438 | 0.0454 | 0.1243 | 0.1410 | 0.1653 | 0.1896 | 0.1165 | 0.1135 | 0.1645 | 0.1564 | 0.3651 | 0.3339 | 0.0018 | 0.0037 | 0.0098 | 0.0331 | 0.1227 | 0.1466 | 0.1110 | 0.1724 | 0.3988 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 489 | 834 | | 12111 | 18609 | 541.6 | 118.52 | 168.67 | 182.80 | 399 | 441 | 476 | 505 | 532 | 559 | 589 | 628 | 690 | 0.0564 | 1049 | 1.226 | 127.68 | 55.00 | 1 | 0.0283 | 343 | 0.0010 | 25.57 | 7.191 | 0.2311 | 307350.0 | 183000000 | 114000000000 | 74500000000000 | 0.4223 | 0.2210 | 0.0002 | 0.0001 | 0.0011 | 0.0003 | 0.0035 | 0.0002 | 0.0121 | 0.0018 | 0.0351 | 0.0123 | 0.0639 | 0.0223 | 0.0770 | 0.0188 | 0.1064 | 0.0282 | 0.7006 | 0.9161 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0017 | 0.0002 | 0.0050 | 0.0010 | 0.0150 | 0.0084 | 0.0268 | 0.0140 | 0.0306 | 0.0093 | 0.0434 | 0.0135 | 0.8767 | 0.9536 | 0.0032 | 0.0045 | 0.0053 | 0.0061 | 0.0150 | 0.0151 | 0.0513 | 0.0363 | 0.0898 | 0.0802 | 0.1165 | 0.1104 | 0.1010 | 0.0726 | 0.1112 | 0.1104 | 0.5067 | 0.5643 | 0.0016 | 0.0023 | 0.0060 | 0.0213 | 0.0499 | 0.0789 | 0.0809 | 0.1040 | 0.6550 | 8 | 14 | 27 | 56 | 102 | 159 | 227 | 312 | 435 | 0.0253 | 65.01 | 6.264 | 0.3576 | 61863.3 | 30100000 | 17400000000 | 11500000000000 | 0.4777 | 0.1891 | 0.0835 | 0.0023 | 0.2306 | 0.0249 | 0.2838 | 0.1678 | 0.1513 | 0.1698 | 0.1153 | 0.1751 | 0.0782 | 0.1769 | 0.0402 | 0.1114 | 0.0146 | 0.0964 | 0.0026 | 0.0755 | 0.0004 | 0.0001 | 0.0000 | 0.0000 | 0.0005 | 0.0009 | 0.0147 | 0.0085 | 0.0655 | 0.0544 | 0.1197 | 0.0976 | 0.0848 | 0.0670 | 0.1186 | 0.1038 | 0.5959 | 0.6678 | 0.0000 | 0.0007 | 0.0011 | 0.0021 | 0.0057 | 0.0062 | 0.0239 | 0.0327 | 0.0959 | 0.1092 | 0.1534 | 0.1697 | 0.1026 | 0.1133 | 0.1390 | 0.1561 | 0.4782 | 0.4101 | 0.0001 | 0.0000 | 0.0024 | 0.0177 | 0.0832 | 0.1361 | 0.0944 | 0.1341 | 0.5320 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 750 | 676 | | 11146 | 21855 | 106.6 | 28.30 | 189.51 | 171.91 | 74 | 83 | 90 | 97 | 103 | 110 | 118 | 128 | 143 | 0.0573 | 1252 | 0.886 | 106.10 | 29.53 | 1 | 0.0241 | 269 | 0.0014 | 32.07 | 6.896 | 0.2173 | 12166.0 | 1490000 | 200000000 | 29600000000 | 0.4458 | 0.2114 | 0.0009 | 0.0000 | 0.0026 | 0.0003 | 0.0096 | 0.0013 | 0.0300 | 0.0038 | 0.0861 | 0.0213 | 0.1508 | 0.0508 | 0.1608 | 0.0587 | 0.1819 | 0.0839 | 0.3773 | 0.7799 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0039 | 0.0003 | 0.0101 | 0.0021 | 0.0393 | 0.0133 | 0.0634 | 0.0258 | 0.0685 | 0.0231 | 0.0980 | 0.0366 | 0.7155 | 0.8988 | 0.0018 | 0.0088 | 0.0088 | 0.0164 | 0.0226 | 0.0582 | 0.0647 | 0.1239 | 0.1317 | 0.2010 | 0.1714 | 0.1795 | 0.1183 | 0.1163 | 0.1423 | 0.1277 | 0.3383 | 0.1681 | 0.0014 | 0.0032 | 0.0116 | 0.0332 | 0.0812 | 0.1162 | 0.1018 | 0.1287 | 0.5226 | 16 | 35 | 67 | 103 | 142 | 190 | 249 | 320 | 433 | 0.0120 | 37.39 | 6.296 | 0.3650 | 65463.6 | 30100000 | 16600000000 | 10400000000000 | 0.5497 | 0.1277 | 0.0358 | 0.0017 | 0.1299 | 0.0109 | 0.2197 | 0.0768 | 0.1613 | 0.1097 | 0.1616 | 0.1610 | 0.1328 | 0.1855 | 0.0738 | 0.1385 | 0.0543 | 0.1308 | 0.0308 | 0.1851 | 0.0000 | 0.0000 | 0.0012 | 0.0012 | 0.0025 | 0.0022 | 0.0135 | 0.0090 | 0.0598 | 0.0462 | 0.1069 | 0.0836 | 0.0781 | 0.0656 | 0.1195 | 0.1003 | 0.6185 | 0.6919 | 0.0006 | 0.0002 | 0.0018 | 0.0023 | 0.0045 | 0.0088 | 0.0267 | 0.0326 | 0.0915 | 0.1031 | 0.1477 | 0.1742 | 0.1100 | 0.1208 | 0.1446 | 0.1560 | 0.4726 | 0.4020 | 0.0002 | 0.0008 | 0.0031 | 0.0184 | 0.0746 | 0.1276 | 0.0976 | 0.1359 | 0.5419 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 541 | 522 | | 7538 | 10729 | 182.1 | 53.16 | 151.55 | 105.15 | 123 | 138 | 150 | 162 | 173 | 185 | 200 | 220 | 253 | 0.0842 | 903 | 1.033 | 124.56 | 28.32 | 1 | 0.0358 | 270 | 0.0011 | 47.33 | 7.166 | 0.1859 | 35971.8 | 7740000 | 1820000000 | 464000000000 | 0.4607 | 0.1986 | 0.0008 | 0.0002 | 0.0033 | 0.0003 | 0.0110 | 0.0014 | 0.0358 | 0.0038 | 0.1099 | 0.0259 | 0.1983 | 0.0649 | 0.1693 | 0.0640 | 0.1888 | 0.0978 | 0.2827 | 0.7419 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0075 | 0.0010 | 0.0464 | 0.0143 | 0.0907 | 0.0329 | 0.0762 | 0.0285 | 0.1180 | 0.0474 | 0.6588 | 0.8759 | 0.0038 | 0.0055 | 0.0070 | 0.0083 | 0.0203 | 0.0290 | 0.0725 | 0.0981 | 0.1462 | 0.1630 | 0.1697 | 0.2003 | 0.1132 | 0.1077 | 0.1373 | 0.1436 | 0.3299 | 0.2445 | 0.0003 | 0.0050 | 0.0050 | 0.0400 | 0.1026 | 0.1488 | 0.1079 | 0.1417 | 0.4487 | 38 | 59 | 80 | 102 | 128 | 157 | 190 | 236 | 297 | 0.0020 | 46.88 | 6.872 | 0.2760 | 34024.8 | 9800000 | 3360000000 | 1320000000000 | 0.5574 | 0.1310 | 0.0165 | 0.0000 | 0.1056 | 0.0050 | 0.2130 | 0.0382 | 0.1703 | 0.0893 | 0.1387 | 0.1551 | 0.1488 | 0.2086 | 0.0826 | 0.1535 | 0.0716 | 0.1259 | 0.0528 | 0.2244 | 0.0005 | 0.0000 | 0.0002 | 0.0006 | 0.0020 | 0.0016 | 0.0138 | 0.0112 | 0.0620 | 0.0424 | 0.1227 | 0.0865 | 0.0888 | 0.0730 | 0.1299 | 0.1037 | 0.5802 | 0.6811 | 0.0006 | 0.0004 | 0.0029 | 0.0049 | 0.0119 | 0.0162 | 0.0365 | 0.0503 | 0.1192 | 0.1521 | 0.1812 | 0.1923 | 0.1190 | 0.1367 | 0.1520 | 0.1559 | 0.3768 | 0.2911 | 0.0002 | 0.0009 | 0.0049 | 0.0238 | 0.0980 | 0.1462 | 0.1128 | 0.1557 | 0.4576 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 770 | 548 | | 4679 | 6669 | 137.8 | 37.32 | 193.13 | 136.78 | 97 | 107 | 115 | 123 | 132 | 140 | 151 | 165 | 188 | 0.1021 | 681 | 1.113 | 90.80 | 33.54 | 1 | 0.0524 | 245 | 0.0018 | 30.73 | 6.604 | 0.2167 | 20392.3 | 3250000 | 560000000 | 104000000000 | 0.4422 | 0.2057 | 0.0004 | 0.0000 | 0.0019 | 0.0000 | 0.0089 | 0.0007 | 0.0355 | 0.0024 | 0.1066 | 0.0257 | 0.1896 | 0.0591 | 0.1776 | 0.0651 | 0.1622 | 0.0905 | 0.3174 | 0.7565 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0043 | 0.0002 | 0.0097 | 0.0009 | 0.0441 | 0.0159 | 0.0819 | 0.0278 | 0.0802 | 0.0248 | 0.1044 | 0.0448 | 0.6745 | 0.8856 | 0.0054 | 0.0052 | 0.0086 | 0.0052 | 0.0119 | 0.0336 | 0.0627 | 0.1059 | 0.1568 | 0.2351 | 0.1859 | 0.2119 | 0.1092 | 0.0801 | 0.1557 | 0.1473 | 0.3038 | 0.1757 | 0.0015 | 0.0020 | 0.0085 | 0.0346 | 0.0989 | 0.1416 | 0.1145 | 0.1401 | 0.4583 | 42 | 70 | 97 | 128 | 161 | 203 | 250 | 305 | 391 | 0.0016 | 66.86 | 7.053 | 0.2296 | 56004.9 | 20500000 | 8680000000 | 4090000000000 | 0.5260 | 0.1564 | 0.0262 | 0.0016 | 0.1229 | 0.0056 | 0.2269 | 0.0334 | 0.1900 | 0.1091 | 0.1859 | 0.1851 | 0.1310 | 0.2201 | 0.0639 | 0.1584 | 0.0336 | 0.1421 | 0.0197 | 0.1445 | 0.0003 | 0.0007 | 0.0009 | 0.0007 | 0.0067 | 0.0024 | 0.0188 | 0.0163 | 0.0733 | 0.0544 | 0.1196 | 0.0928 | 0.0999 | 0.0728 | 0.1330 | 0.1079 | 0.5475 | 0.6521 | 0.0022 | 0.0017 | 0.0045 | 0.0063 | 0.0085 | 0.0150 | 0.0368 | 0.0600 | 0.1188 | 0.1298 | 0.1645 | 0.1997 | 0.1215 | 0.1298 | 0.1551 | 0.1558 | 0.3882 | 0.3018 | 0.0011 | 0.0032 | 0.0056 | 0.0275 | 0.0898 | 0.1479 | 0.1127 | 0.1437 | 0.4687 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 816 | 393 | | 5950 | 11342 | 117.6 | 33.32 | 249.29 | 173.91 | 81 | 90 | 98 | 105 | 112 | 120 | 129 | 141 | 162 | 0.0886 | 1005 | 0.628 | 179.79 | 48.30 | 1 | 0.0987 | 587 | 0.0027 | 14.82 | 6.257 | 0.2986 | 14935.3 | 2060000 | 307000000 | 49700000000 | 0.4437 | 0.2043 | 0.0009 | 0.0002 | 0.0033 | 0.0000 | 0.0082 | 0.0002 | 0.0331 | 0.0046 | 0.0759 | 0.0228 | 0.1588 | 0.0532 | 0.1527 | 0.0566 | 0.1907 | 0.0777 | 0.3764 | 0.7848 | 0.0005 | 0.0002 | 0.0014 | 0.0000 | 0.0036 | 0.0002 | 0.0167 | 0.0016 | 0.0351 | 0.0130 | 0.0689 | 0.0288 | 0.0680 | 0.0227 | 0.0975 | 0.0363 | 0.7084 | 0.8972 | 0.0052 | 0.0056 | 0.0070 | 0.0056 | 0.0235 | 0.0206 | 0.0506 | 0.0882 | 0.0950 | 0.1689 | 0.1578 | 0.1388 | 0.1046 | 0.1107 | 0.1290 | 0.1370 | 0.4272 | 0.3246 | 0.0020 | 0.0051 | 0.0094 | 0.0279 | 0.0822 | 0.1188 | 0.0917 | 0.1200 | 0.5429 | 40 | 81 | 128 | 176 | 225 | 279 | 333 | 394 | 483 | 0.0016 | 78.48 | 7.365 | 0.2033 | 92387.6 | 42200000 | 22200000000 | 13200000000000 | 0.4848 | 0.1839 | 0.0286 | 0.0012 | 0.1297 | 0.0127 | 0.2654 | 0.0476 | 0.1826 | 0.1174 | 0.1568 | 0.1874 | 0.1170 | 0.2093 | 0.0749 | 0.1488 | 0.0314 | 0.1305 | 0.0136 | 0.1451 | 0.0005 | 0.0000 | 0.0003 | 0.0013 | 0.0040 | 0.0026 | 0.0198 | 0.0140 | 0.0727 | 0.0554 | 0.1270 | 0.1033 | 0.1058 | 0.0836 | 0.1312 | 0.1196 | 0.5388 | 0.6202 | 0.0012 | 0.0026 | 0.0065 | 0.0077 | 0.0102 | 0.0148 | 0.0349 | 0.0586 | 0.1118 | 0.1501 | 0.1780 | 0.1978 | 0.1268 | 0.1369 | 0.1581 | 0.1553 | 0.3725 | 0.2761 | 0.0002 | 0.0031 | 0.0062 | 0.0306 | 0.0849 | 0.1491 | 0.1161 | 0.1500 | 0.4598 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 726 | 600 | | 3242 | 14311 | 499.5 | 83.43 | 217.74 | 192.04 | 394 | 426 | 450 | 470 | 493 | 518 | 547 | 576 | 612 | 0.0641 | 917 | 0.675 | 101.83 | 25.18 | 1 | 0.0999 | 324 | 0.0014 | 30.06 | 6.786 | 0.2232 | 256441.0 | 135000000 | 73000000000 | 40400000000000 | 0.4615 | 0.1909 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0003 | 0.0094 | 0.0019 | 0.0476 | 0.0128 | 0.1034 | 0.0350 | 0.0932 | 0.0172 | 0.1211 | 0.0428 | 0.6215 | 0.8900 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0031 | 0.0015 | 0.0241 | 0.0115 | 0.0544 | 0.0319 | 0.0457 | 0.0124 | 0.0582 | 0.0254 | 0.8139 | 0.9170 | 0.0069 | 0.2000 | 0.0185 | 0.2000 | 0.0254 | 0.1333 | 0.0762 | 0.2667 | 0.1224 | 0.0667 | 0.2517 | 0.1333 | 0.1201 | 0.0000 | 0.1386 | 0.0000 | 0.2402 | 0.0000 | 0.0026 | 0.0013 | 0.0110 | 0.0272 | 0.0725 | 0.1146 | 0.0881 | 0.1075 | 0.5751 | 27 | 59 | 91 | 117 | 149 | 197 | 277 | 373 | 502 | 0.0056 | 39.72 | 6.385 | 0.3525 | 84287.2 | 43400000 | 26300000000 | 17700000000000 | 0.5008 | 0.1648 | 0.0367 | 0.0032 | 0.1371 | 0.0092 | 0.2234 | 0.0566 | 0.1856 | 0.1095 | 0.1607 | 0.1802 | 0.1201 | 0.1909 | 0.0615 | 0.1404 | 0.0434 | 0.1268 | 0.0316 | 0.1831 | 0.0010 | 0.0008 | 0.0021 | 0.0015 | 0.0046 | 0.0040 | 0.0193 | 0.0143 | 0.0618 | 0.0534 | 0.0900 | 0.0837 | 0.0683 | 0.0638 | 0.1015 | 0.0908 | 0.6515 | 0.6878 | 0.0004 | 0.0008 | 0.0007 | 0.0042 | 0.0048 | 0.0124 | 0.0253 | 0.0287 | 0.0830 | 0.0944 | 0.1247 | 0.1404 | 0.1000 | 0.1138 | 0.1419 | 0.1548 | 0.5192 | 0.4506 | 0.0006 | 0.0023 | 0.0015 | 0.0250 | 0.0581 | 0.1139 | 0.0806 | 0.1154 | 0.6027 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 791 | 738 | | 2836 | 2758 | 119.5 | 28.32 | 225.10 | 172.38 | 89 | 99 | 105 | 111 | 115 | 121 | 128 | 137 | 155 | 0.1653 | 456 | 0.603 | 236.69 | 51.26 | 1 | 0.2341 | 664 | 0.0036 | 15.13 | 5.972 | 0.2993 | 15085.0 | 2020000 | 291000000 | 45400000000 | 0.4422 | 0.2144 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0021 | 0.0000 | 0.0185 | 0.0042 | 0.0723 | 0.0261 | 0.1083 | 0.0465 | 0.1591 | 0.0519 | 0.1657 | 0.0711 | 0.4736 | 0.7998 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0067 | 0.0011 | 0.0387 | 0.0176 | 0.0627 | 0.0269 | 0.0753 | 0.0298 | 0.0867 | 0.0384 | 0.7285 | 0.8863 | 0.0070 | 0.0054 | 0.0234 | 0.0163 | 0.0422 | 0.0217 | 0.0749 | 0.0761 | 0.1218 | 0.1848 | 0.1124 | 0.1902 | 0.1101 | 0.1196 | 0.1077 | 0.1413 | 0.4005 | 0.2446 | 0.0041 | 0.0033 | 0.0231 | 0.0430 | 0.1017 | 0.1479 | 0.1083 | 0.1380 | 0.4306 | 20 | 53 | 93 | 143 | 203 | 256 | 310 | 368 | 462 | 0.0047 | 47.42 | 6.617 | 0.2813 | 80370.2 | 35100000 | 17400000000 | 9480000000000 | 0.5310 | 0.1251 | 0.0062 | 0.0011 | 0.1040 | 0.0067 | 0.1996 | 0.0540 | 0.2100 | 0.1012 | 0.1580 | 0.1609 | 0.1393 | 0.2014 | 0.1123 | 0.1620 | 0.0499 | 0.1215 | 0.0208 | 0.1912 | 0.0000 | 0.0000 | 0.0007 | 0.0012 | 0.0033 | 0.0024 | 0.0127 | 0.0135 | 0.0560 | 0.0483 | 0.1133 | 0.0889 | 0.0833 | 0.0700 | 0.1227 | 0.0948 | 0.6080 | 0.6810 | 0.0000 | 0.0025 | 0.0010 | 0.0074 | 0.0059 | 0.0086 | 0.0285 | 0.0395 | 0.1050 | 0.1210 | 0.1501 | 0.1444 | 0.0991 | 0.1222 | 0.1511 | 0.1543 | 0.4593 | 0.4000 | 0.0008 | 0.0008 | 0.0032 | 0.0244 | 0.0630 | 0.1198 | 0.1072 | 0.1308 | 0.5500 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 701 | 856 | | 7996 | 17307 | 193.6 | 58.72 | 164.59 | 174.51 | 125 | 142 | 158 | 171 | 186 | 201 | 219 | 242 | 276 | 0.0699 | 1209 | 0.390 | 189.19 | 52.01 | 6 | 0.0969 | 775 | 0.0004 | 115.49 | 7.998 | 0.1188 | 40941.8 | 9380000 | 2310000000 | 607000000000 | 0.4229 | 0.2241 | 0.0005 | 0.0000 | 0.0018 | 0.0002 | 0.0094 | 0.0009 | 0.0411 | 0.0074 | 0.1168 | 0.0344 | 0.1900 | 0.0791 | 0.1790 | 0.0803 | 0.1954 | 0.1104 | 0.2659 | 0.6873 | 0.0003 | 0.0000 | 0.0010 | 0.0001 | 0.0019 | 0.0003 | 0.0127 | 0.0035 | 0.0368 | 0.0179 | 0.0736 | 0.0397 | 0.0694 | 0.0336 | 0.0989 | 0.0501 | 0.7053 | 0.8549 | 0.0011 | 0.0022 | 0.0058 | 0.0101 | 0.0132 | 0.0348 | 0.0529 | 0.0886 | 0.1242 | 0.1502 | 0.1564 | 0.1973 | 0.1036 | 0.1424 | 0.1416 | 0.1323 | 0.4012 | 0.2422 | 0.0011 | 0.0014 | 0.0067 | 0.0338 | 0.0799 | 0.1053 | 0.1028 | 0.1274 | 0.5416 | 12 | 17 | 27 | 57 | 103 | 156 | 220 | 301 | 416 | 0.0341 | 36.46 | 5.746 | 0.4218 | 57539.3 | 27000000 | 15300000000 | 10100000000000 | 0.6571 | 0.0586 | 0.0542 | 0.0031 | 0.1783 | 0.0167 | 0.2744 | 0.0940 | 0.1826 | 0.1421 | 0.1310 | 0.1851 | 0.0908 | 0.1972 | 0.0521 | 0.1171 | 0.0258 | 0.1158 | 0.0107 | 0.1290 | 0.0001 | 0.0001 | 0.0009 | 0.0003 | 0.0035 | 0.0017 | 0.0141 | 0.0100 | 0.0637 | 0.0508 | 0.1127 | 0.0947 | 0.0879 | 0.0669 | 0.1267 | 0.1070 | 0.5903 | 0.6684 | 0.0002 | 0.0012 | 0.0024 | 0.0030 | 0.0050 | 0.0089 | 0.0260 | 0.0344 | 0.0869 | 0.1000 | 0.1472 | 0.1606 | 0.1046 | 0.1172 | 0.1475 | 0.1538 | 0.4802 | 0.4209 | 0.0006 | 0.0016 | 0.0037 | 0.0192 | 0.0754 | 0.1313 | 0.0961 | 0.1295 | 0.5426 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 931 | 115 | | 3279 | 6983 | 116.8 | 25.16 | 91.19 | 65.40 | 87 | 94 | 101 | 107 | 114 | 121 | 129 | 138 | 151 | 0.0971 | 678 | 0.521 | 85.63 | 18.00 | 1 | 0.0753 | 247 | 0.0015 | 34.98 | 6.738 | 0.2061 | 14263.7 | 1820000 | 243000000 | 33600000000 | 0.4567 | 0.1958 | 0.0015 | 0.0000 | 0.0044 | 0.0000 | 0.0174 | 0.0003 | 0.0377 | 0.0055 | 0.0856 | 0.0281 | 0.1393 | 0.0445 | 0.1581 | 0.0448 | 0.1978 | 0.0726 | 0.3583 | 0.8042 | 0.0011 | 0.0000 | 0.0026 | 0.0000 | 0.0049 | 0.0003 | 0.0098 | 0.0003 | 0.0448 | 0.0203 | 0.0726 | 0.0276 | 0.0704 | 0.0218 | 0.1099 | 0.0470 | 0.6839 | 0.8827 | 0.0068 | 0.0000 | 0.0102 | 0.0382 | 0.0441 | 0.0892 | 0.0849 | 0.1401 | 0.1494 | 0.2038 | 0.1511 | 0.1975 | 0.1324 | 0.1592 | 0.1647 | 0.0701 | 0.2564 | 0.1019 | 0.0026 | 0.0072 | 0.0132 | 0.0349 | 0.0829 | 0.1250 | 0.0980 | 0.1342 | 0.5020 | 26 | 35 | 46 | 59 | 74 | 91 | 112 | 140 | 183 | 0.0140 | 7.49 | 5.001 | 0.4623 | 12591.6 | 2290000 | 504000000 | 127000000000 | 0.5517 | 0.1402 | 0.0219 | 0.0015 | 0.1015 | 0.0080 | 0.1790 | 0.0298 | 0.2075 | 0.0795 | 0.2009 | 0.1677 | 0.1286 | 0.2109 | 0.0825 | 0.1702 | 0.0475 | 0.1583 | 0.0307 | 0.1742 | 0.0011 | 0.0005 | 0.0025 | 0.0032 | 0.0070 | 0.0029 | 0.0242 | 0.0174 | 0.0752 | 0.0594 | 0.1144 | 0.0807 | 0.1014 | 0.0818 | 0.1355 | 0.1148 | 0.5386 | 0.6392 | 0.0009 | 0.0042 | 0.0060 | 0.0072 | 0.0133 | 0.0240 | 0.0486 | 0.0665 | 0.1298 | 0.1450 | 0.1660 | 0.1905 | 0.1243 | 0.1240 | 0.1596 | 0.1534 | 0.3517 | 0.2852 | 0.0021 | 0.0046 | 0.0099 | 0.0368 | 0.0916 | 0.1561 | 0.1164 | 0.1465 | 0.4360 |