High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MDA-MB-231 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 187 499 image if available 5159 11813 530.2 150.73 46.53 99.31 336 405 473 515 555 600 635 664 696 0.0781 923 1.105 73.82 25.55 4 0.0382 197 0.0006 44.92 7.570 0.1925 303806.0
182000000
112000000000
70800000000000
0.3690 0.2568 0.0020 0.0000 0.0029 0.0000 0.0069 0.0004 0.0167 0.0024 0.0587 0.0163 0.0953 0.0308 0.0843 0.0238 0.1059 0.0400 0.6273 0.8863 0.0005 0.0000 0.0002 0.0000 0.0007 0.0000 0.0025 0.0021 0.0185 0.0146 0.0285 0.0275 0.0217 0.0173 0.0307 0.0266 0.8966 0.9119 0.0019 0.0635 0.0052 0.0476 0.0110 0.1270 0.0213 0.1429 0.0549 0.0635 0.0614 0.1270 0.0627 0.0952 0.1008 0.1270 0.6807 0.2063 0.0010 0.0024 0.0038 0.0076 0.0244 0.0344 0.0337 0.0485 0.8443 6 8 9 10 11 13 17 52 137 0.1781 7.69 3.150 0.7073 12026.7
6360000
4770000000
4300000000000
0.4827 0.1912 0.0208 0.0043 0.0655 0.0157 0.1042 0.0386 0.1548 0.0815 0.1935 0.1302 0.1905 0.1774 0.1488 0.1245 0.0893 0.1660 0.0327 0.2618 0.0004 0.0007 0.0004 0.0018 0.0011 0.0036 0.0042 0.0075 0.0229 0.0220 0.0362 0.0341 0.0320 0.0242 0.0526 0.0512 0.8502 0.8550 0.0000 0.0000 0.0022 0.0019 0.0044 0.0033 0.0079 0.0071 0.0271 0.0288 0.0411 0.0506 0.0389 0.0378 0.0599 0.0624 0.8186 0.8080 0.0000 0.0012 0.0032 0.0085 0.0263 0.0388 0.0324 0.0599 0.8297
MCF7 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 841 100 image if available 7377 24941 386.3 96.75 88.88 190.82 262 298 330 360 385 408 433 466 515 0.0500 1246 0.563 94.76 26.17 2 0.0409 302 0.0008 47.55 7.415 0.1751 158588.0
68800000
31400000000
15000000000000
0.4311 0.2177 0.0002 0.0000 0.0031 0.0005 0.0070 0.0012 0.0283 0.0041 0.0813 0.0252 0.1505 0.0529 0.1401 0.0558 0.1607 0.0799 0.4286 0.7805 0.0000 0.0000 0.0011 0.0001 0.0023 0.0003 0.0099 0.0018 0.0340 0.0163 0.0593 0.0332 0.0508 0.0272 0.0661 0.0402 0.7764 0.8808 0.0040 0.0130 0.0066 0.0238 0.0139 0.0563 0.0615 0.0909 0.1315 0.1970 0.1606 0.1710 0.1269 0.1255 0.1401 0.1299 0.3549 0.1926 0.0005 0.0014 0.0043 0.0220 0.0674 0.1016 0.1003 0.1272 0.5753 4 5 7 8 10 12 18 103 322 0.1971 13.23 3.393 0.6457 44309.3
31100000
25500000000
23000000000000
0.4510 0.1554 0.0309 0.0028 0.1373 0.0130 0.2921 0.0763 0.2205 0.1516 0.1431 0.2140 0.0986 0.1898 0.0271 0.1395 0.0213 0.1116 0.0290 0.1014 0.0000 0.0003 0.0009 0.0005 0.0007 0.0016 0.0037 0.0063 0.0213 0.0191 0.0374 0.0318 0.0250 0.0278 0.0407 0.0377 0.8703 0.8748 0.0000 0.0002 0.0008 0.0004 0.0004 0.0019 0.0063 0.0064 0.0259 0.0282 0.0468 0.0526 0.0377 0.0404 0.0539 0.0614 0.8281 0.8084 0.0000 0.0004 0.0008 0.0042 0.0213 0.0423 0.0293 0.0477 0.8540
Hs 578T A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 395 909 image if available 589 5786 12.0 2.37 6.24 2.23 9 10 11 11 12 12 13 14 15 0.0990 573 0.731 73.43 17.00 0 0.3192 188 0.0185 6.32 4.289 0.3960 150.6
1953.66
26252.6
364792
0.3695 0.2656 0.0046 0.0000 0.0069 0.0018 0.0324 0.0036 0.0694 0.0164 0.1019 0.0455 0.1343 0.0764 0.1898 0.1218 0.1736 0.1818 0.2870 0.5527 0.0000 0.0000 0.0077 0.0000 0.0174 0.0017 0.0367 0.0156 0.0405 0.0363 0.0656 0.0554 0.1158 0.0606 0.1409 0.1125 0.5753 0.7180 0.0581 0.2857 0.0930 0.2500 0.1860 0.1071 0.1163 0.1786 0.1744 0.1071 0.1163 0.0714 0.0814 0.0000 0.1163 0.0000 0.0581 0.0000 0.0153 0.0337 0.0706 0.0982 0.1135 0.1350 0.1380 0.1503 0.2454 3 4 5 6 6 7 7 8 9 0.0198 11.10 4.314 0.3248 43.9
336.777
2778.03
24382.5
0.5530 0.1191 0.0068 0.0000 0.0407 0.0041 0.1143 0.0182 0.2166 0.0597 0.2673 0.1261 0.2088 0.2311 0.1023 0.2725 0.0370 0.2133 0.0062 0.0750 0.0000 0.0000 0.0016 0.0006 0.0121 0.0032 0.0364 0.0132 0.0907 0.0355 0.1684 0.0778 0.2678 0.1906 0.2778 0.3647 0.1454 0.3144 0.1144 0.2816 0.2397 0.3609 0.2950 0.2346 0.1896 0.0927 0.1073 0.0268 0.0392 0.0034 0.0141 0.0000 0.0006 0.0000 0.0000 0.0000 0.0018 0.0090 0.0356 0.0844 0.1569 0.2511 0.2490 0.1644 0.0477
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 259 595 image if available 3281 8845 537.2 98.78 47.70 69.98 406 455 487 513 535 555 578 608 681 0.0684 605 1.005 109.84 37.48 2 0.0884 290 0.0012 24.77 6.942 0.2330 298323.0
171000000
101000000000
61500000000000
0.4559 0.1915 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0076 0.0006 0.0295 0.0159 0.0565 0.0312 0.0510 0.0243 0.0674 0.0328 0.7880 0.8952 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0039 0.0006 0.0159 0.0128 0.0297 0.0253 0.0244 0.0131 0.0304 0.0186 0.8956 0.9295 0.0066 0.0137 0.0088 0.0274 0.0243 0.0959 0.0133 0.0959 0.0575 0.2055 0.0973 0.1507 0.0619 0.1096 0.0841 0.1507 0.6460 0.1507 0.0012 0.0000 0.0025 0.0204 0.0532 0.0835 0.0884 0.1070 0.6438 8 9 11 12 14 19 46 78 131 0.2066 2.60 3.143 0.7617 7171.8
1810000
603000000
239000000000
0.5155 0.1378 0.0352 0.0029 0.0580 0.0155 0.0890 0.0638 0.1201 0.0629 0.1532 0.0977 0.1636 0.1460 0.1822 0.1199 0.1387 0.1586 0.0600 0.3327 0.0007 0.0007 0.0014 0.0020 0.0021 0.0029 0.0064 0.0085 0.0152 0.0186 0.0258 0.0232 0.0237 0.0235 0.0488 0.0405 0.8759 0.8803 0.0017 0.0015 0.0009 0.0039 0.0064 0.0064 0.0111 0.0148 0.0273 0.0261 0.0413 0.0542 0.0388 0.0473 0.0725 0.0719 0.8001 0.7740 0.0008 0.0008 0.0035 0.0096 0.0207 0.0261 0.0337 0.0560 0.8489
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 353 558 image if available 3264 13261 567.7 97.23 20.25 30.53 423 480 524 555 578 601 624 651 686 0.0525 696 0.829 83.26 24.17 2 0.0757 247 0.0012 24.55 6.947 0.2311 331741.0
199000000
122000000000
75900000000000
0.3761 0.2603 0.0000 0.0000 0.0000 0.0000 0.0013 0.0000 0.0042 0.0015 0.0348 0.0117 0.0809 0.0329 0.0637 0.0151 0.0926 0.0194 0.7227 0.9195 0.0000 0.0000 0.0000 0.0000 0.0007 0.0000 0.0018 0.0012 0.0138 0.0117 0.0348 0.0322 0.0210 0.0129 0.0246 0.0169 0.9033 0.9251 0.0000 0.0000 0.0134 0.0000 0.0267 0.0000 0.0829 0.2000 0.1337 0.2000 0.2086 0.2000 0.1310 0.2000 0.1230 0.2000 0.2807 0.0000 0.0000 0.0011 0.0022 0.0117 0.0458 0.1011 0.0844 0.1000 0.6536 6 8 9 10 11 13 15 19 43 0.3560 0.58 1.966 0.8565 1342.4
217327
52700000
15600000000
0.5872 0.1138 0.0827 0.0402 0.0911 0.0460 0.0905 0.0583 0.1079 0.0708 0.1235 0.1009 0.1307 0.1071 0.1589 0.1225 0.1457 0.1493 0.0689 0.3048 0.0327 0.0279 0.0346 0.0300 0.0335 0.0375 0.0372 0.0451 0.0380 0.0643 0.0515 0.0758 0.0560 0.0781 0.0861 0.0967 0.6304 0.5445 0.0142 0.0053 0.0137 0.0053 0.0132 0.0107 0.0179 0.0165 0.0189 0.0256 0.0344 0.0373 0.0387 0.0453 0.0783 0.0719 0.7708 0.7821 0.0197 0.0239 0.0239 0.0337 0.0322 0.0405 0.0348 0.0594 0.7319
MDA-MB-231 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 248 500 image if available 1039 2688 496.1 98.73 39.06 62.95 376 424 458 485 504 521 536 562 631 0.1365 367 0.740 130.00 22.83 1 0.2849 296 0.0017 65.54 6.527 0.1617 255811.0
136000000
73900000000
41200000000000
0.4036 0.2366 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0054 0.0020 0.0499 0.0318 0.0823 0.0417 0.0702 0.0328 0.0931 0.0557 0.6991 0.8360 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0011 0.0020 0.0324 0.0307 0.0525 0.0396 0.0357 0.0277 0.0558 0.0455 0.8225 0.8546 0.0000 0.0000 0.0000 0.2000 0.0065 0.6000 0.0258 0.2000 0.0710 0.0000 0.0903 0.0000 0.0645 0.0000 0.1032 0.0000 0.6387 0.0000 0.0000 0.0017 0.0017 0.0174 0.0522 0.0922 0.0783 0.0939 0.6626 7 8 10 13 15 18 23 43 112 0.1239 2.12 3.167 0.7441 5486.9
1350000
417000000
146000000000
0.5373 0.1116 0.0154 0.0541 0.0538 0.0510 0.0846 0.0318 0.1231 0.0701 0.1231 0.0987 0.2077 0.0955 0.1462 0.1178 0.1538 0.2102 0.0923 0.2707 0.0031 0.0211 0.0108 0.0199 0.0093 0.0112 0.0170 0.0211 0.0216 0.0373 0.0386 0.0398 0.0448 0.0460 0.0802 0.1007 0.7747 0.7027 0.0039 0.0020 0.0039 0.0000 0.0019 0.0041 0.0135 0.0122 0.0251 0.0245 0.0290 0.0306 0.0444 0.0510 0.0734 0.0592 0.8050 0.8163 0.0070 0.0053 0.0088 0.0140 0.0298 0.0385 0.0403 0.0788 0.7776
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 561 247 image if available 4445 15033 466.1 65.09 63.62 138.06 379 413 433 450 466 481 499 521 551 0.0559 840 1.186 46.40 17.49 1 0.0270 120 0.0015 34.76 6.820 0.2169 221513.0
107000000
52800000000
26400000000000
0.4116 0.2311 0.0000 0.0000 0.0000 0.0000 0.0011 0.0000 0.0035 0.0002 0.0355 0.0137 0.0646 0.0248 0.0635 0.0142 0.0910 0.0205 0.7407 0.9266 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0020 0.0002 0.0221 0.0137 0.0368 0.0248 0.0314 0.0142 0.0456 0.0187 0.8620 0.9284 0.0110 1.0000 0.0192 0.0000 0.0219 0.0000 0.0959 0.0000 0.1479 0.0000 0.1726 0.0000 0.1397 0.0000 0.1288 0.0000 0.2630 0.0000 0.0004 0.0036 0.0085 0.0278 0.0732 0.0996 0.0961 0.1302 0.5606 7 8 9 10 12 15 22 57 200 0.2619 11.61 3.053 0.7574 23105.5
14100000
11000000000
10100000000000
0.4691 0.1844 0.0363 0.0081 0.0726 0.0208 0.0726 0.0728 0.1501 0.0786 0.1622 0.1110 0.1671 0.1260 0.1574 0.1191 0.1090 0.1445 0.0726 0.3191 0.0003 0.0012 0.0013 0.0030 0.0023 0.0044 0.0077 0.0094 0.0229 0.0195 0.0265 0.0301 0.0245 0.0248 0.0368 0.0387 0.8777 0.8689 0.0011 0.0000 0.0011 0.0004 0.0022 0.0024 0.0108 0.0091 0.0238 0.0234 0.0309 0.0313 0.0313 0.0317 0.0395 0.0527 0.8593 0.8490 0.0003 0.0007 0.0048 0.0104 0.0214 0.0308 0.0235 0.0443 0.8637
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1201 147 image if available 25401 21792 80.3 36.47 7.79 3.16 47 51 55 60 67 79 95 111 130 0.0646 1407 0.643 109.48 22.02 3 0.0122 311 0.0238 1.54 4.339 0.6433 7784.7
930349
141000000
27400000000
0.3746 0.2574 0.0183 0.0041 0.0285 0.0101 0.0332 0.0165 0.0445 0.0216 0.0579 0.0307 0.0760 0.0454 0.0991 0.0645 0.1547 0.1011 0.4878 0.7059 0.0063 0.0025 0.0088 0.0051 0.0101 0.0093 0.0128 0.0127 0.0158 0.0171 0.0202 0.0254 0.0263 0.0353 0.0450 0.0545 0.8547 0.8381 0.0029 0.0096 0.0051 0.0076 0.0087 0.0135 0.0154 0.0237 0.0181 0.0317 0.0252 0.0416 0.0356 0.0590 0.0614 0.0833 0.8277 0.7300 0.0039 0.0045 0.0066 0.0106 0.0121 0.0194 0.0250 0.0402 0.8777 4 5 6 7 8 9 9 10 12 0.3288 0.54 1.489 0.7679 70.7
710.738
7758.34
90867.1
0.5651 0.1468 0.0276 0.0002 0.1012 0.0027 0.1830 0.0162 0.2395 0.0448 0.2232 0.1065 0.1440 0.1983 0.0622 0.2724 0.0175 0.2494 0.0018 0.1095 0.0011 0.0001 0.0095 0.0007 0.0313 0.0047 0.0743 0.0148 0.1392 0.0405 0.2209 0.1002 0.2544 0.1989 0.1985 0.3291 0.0707 0.3109 0.0837 0.3817 0.2220 0.3524 0.2715 0.1695 0.2102 0.0699 0.1317 0.0232 0.0547 0.0028 0.0218 0.0004 0.0035 0.0000 0.0010 0.0000 0.0061 0.0422 0.1149 0.1974 0.2403 0.2128 0.1308 0.0484 0.0072
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 568 142 image if available 3390 3676 488.2 76.89 55.99 95.47 384 420 448 473 493 513 533 556 587 0.1317 484 0.859 109.18 23.32 5 0.0752 255 0.0012 41.51 6.959 0.2091 244289.0
125000000
65200000000
34600000000000
0.4456 0.2022 0.0000 0.0000 0.0000 0.0000 0.0019 0.0000 0.0133 0.0009 0.0451 0.0139 0.0863 0.0237 0.0833 0.0160 0.1064 0.0261 0.6638 0.9194 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0050 0.0009 0.0220 0.0139 0.0441 0.0237 0.0414 0.0154 0.0588 0.0231 0.8284 0.9230 0.0028 0.0000 0.0113 1.0000 0.0395 0.0000 0.1073 0.0000 0.1638 0.0000 0.2147 0.0000 0.1243 0.0000 0.1356 0.0000 0.2006 0.0000 0.0006 0.0017 0.0045 0.0195 0.0658 0.1155 0.1016 0.1267 0.5642 9 11 12 14 17 20 25 75 169 0.1554 6.68 3.147 0.7267 12247.2
4240000
1770000000
834000000000
0.4752 0.1492 0.0192 0.0284 0.0769 0.0355 0.1731 0.1277 0.3462 0.1489 0.1346 0.1915 0.1346 0.1773 0.1154 0.1206 0.0000 0.0709 0.0000 0.0993 0.0000 0.0046 0.0025 0.0058 0.0012 0.0116 0.0037 0.0127 0.0160 0.0197 0.0197 0.0313 0.0271 0.0174 0.0406 0.0440 0.8892 0.8530 0.0000 0.0000 0.0000 0.0000 0.0026 0.0028 0.0039 0.0083 0.0211 0.0221 0.0316 0.0456 0.0395 0.0415 0.0684 0.0692 0.8329 0.8105 0.0000 0.0000 0.0013 0.0038 0.0189 0.0215 0.0278 0.0556 0.8712
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 462 109 image if available 459 1169 64.3 13.23 8.02 2.47 48 52 57 61 64 67 71 74 79 0.2515 294 0.892 64.33 20.81 1 0.3791 174 0.0526 1.06 3.212 0.6390 4308.5
301320
22000000
1690000000
0.4020 0.2263 0.0000 0.0000 0.0063 0.0023 0.0094 0.0068 0.0408 0.0068 0.0940 0.0502 0.1160 0.1073 0.1473 0.0662 0.2508 0.0936 0.3354 0.6667 0.0000 0.0000 0.0026 0.0022 0.0026 0.0066 0.0238 0.0044 0.0556 0.0462 0.0635 0.0879 0.0714 0.0505 0.1111 0.0725 0.6693 0.7297 0.0678 0.0000 0.0508 0.0000 0.1356 0.0588 0.0339 0.1176 0.2034 0.2941 0.1186 0.1176 0.0678 0.1176 0.1356 0.2353 0.1864 0.0588 0.0041 0.0041 0.0245 0.0245 0.0735 0.0939 0.0898 0.1796 0.5061 5 6 7 7 8 9 9 10 11 0.0200 12.70 4.330 0.3019 70.5
664.57
6651.59
70129.1
0.5248 0.1240 0.0136 0.0000 0.0492 0.0010 0.1121 0.0149 0.2462 0.0378 0.2394 0.0746 0.2190 0.1303 0.1002 0.2139 0.0187 0.2806 0.0017 0.2468 0.0000 0.0000 0.0099 0.0009 0.0221 0.0027 0.0585 0.0220 0.1170 0.0577 0.2064 0.0843 0.2274 0.1357 0.2506 0.2878 0.1082 0.4088 0.1199 0.5814 0.2461 0.2907 0.2366 0.0814 0.1924 0.0349 0.1293 0.0116 0.0536 0.0000 0.0158 0.0000 0.0032 0.0000 0.0032 0.0000 0.0126 0.0535 0.1258 0.2013 0.2186 0.1714 0.1336 0.0708 0.0126
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 516 891 image if available 618 739 106.8 15.78 5.93 2.23 82 92 99 105 109 114 118 121 125 0.3234 239 1.055 76.24 24.70 1 0.3026 187 0.0261 2.24 3.925 0.5232 11645.2
1290000
146000000
16700000000
0.3863 0.2434 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0199 0.0000 0.0358 0.0405 0.0875 0.0631 0.1093 0.0275 0.1590 0.0469 0.5885 0.8220 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0188 0.0000 0.0282 0.0405 0.0545 0.0631 0.0545 0.0275 0.0395 0.0469 0.8045 0.8220 0.1034 0.0000 0.2414 0.0000 0.2414 0.0000 0.2414 0.0000 0.1034 0.0000 0.0690 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0277 0.0360 0.0305 0.0637 0.0665 0.1108 0.6648 3 4 5 5 6 7 7 8 9 0.5158 0.30 0.942 0.8384 40.2
298.797
2399.87
20613.1
0.4399 0.1643 0.0054 0.0000 0.0863 0.0054 0.1563 0.0342 0.3100 0.1081 0.2022 0.1856 0.1725 0.2270 0.0566 0.2378 0.0108 0.1640 0.0000 0.0378 0.0000 0.0000 0.0186 0.0016 0.0557 0.0188 0.1002 0.0518 0.1670 0.1256 0.2041 0.1680 0.2059 0.2135 0.1837 0.2370 0.0649 0.1837 0.1845 0.4878 0.2917 0.2195 0.2440 0.2195 0.2024 0.0732 0.0476 0.0000 0.0298 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0213 0.0520 0.1348 0.1442 0.1891 0.1915 0.1277 0.1040 0.0355
Hs 578T A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 477 785 image if available 2057 7126 15.8 5.35 5.58 1.94 10 11 13 14 15 16 18 20 22 0.1343 957 1.077 39.62 14.00 0 0.0501 103 0.0083 6.76 5.098 0.3940 278.8
5536.95
125712
3300000
0.3803 0.2578 0.0068 0.0000 0.0241 0.0017 0.0395 0.0081 0.0656 0.0237 0.1070 0.0317 0.1466 0.0531 0.1688 0.1073 0.2054 0.1604 0.2363 0.6140 0.0048 0.0000 0.0131 0.0010 0.0220 0.0068 0.0275 0.0167 0.0440 0.0256 0.0557 0.0329 0.0688 0.0605 0.0922 0.0924 0.6717 0.7641 0.0168 0.0437 0.0216 0.0437 0.0481 0.0328 0.0793 0.0656 0.0865 0.1038 0.1346 0.1093 0.1298 0.0710 0.1394 0.1749 0.3438 0.3552 0.0178 0.0231 0.0241 0.0409 0.0409 0.0682 0.0860 0.1091 0.5897 3 4 5 5 5 6 6 7 8 0.0254 8.33 4.093 0.3635 34.9
237.89
1743
13611.8
0.5441 0.1416 0.0029 0.0002 0.0262 0.0017 0.0867 0.0113 0.1633 0.0354 0.2318 0.0789 0.2315 0.1447 0.1584 0.2575 0.0821 0.2968 0.0170 0.1734 0.0004 0.0002 0.0045 0.0006 0.0189 0.0043 0.0680 0.0220 0.1231 0.0509 0.2194 0.0876 0.2719 0.1709 0.2172 0.3403 0.0767 0.3232 0.2384 0.4990 0.3216 0.3638 0.2659 0.1113 0.1235 0.0258 0.0369 0.0000 0.0129 0.0000 0.0009 0.0000 0.0000 0.0000 0.0000 0.0000 0.0115 0.0662 0.1649 0.2477 0.2359 0.1587 0.0825 0.0266 0.0059
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 902 305 image if available 577 1224 107.4 19.71 5.63 1.94 82 89 96 101 108 113 118 125 133 0.2230 273 1.197 35.36 14.21 1 0.1664 96 0.0277 1.58 3.824 0.5880 11913.2
1360000
161000000
19400000000
0.3940 0.2372 0.0000 0.0000 0.0025 0.0000 0.0051 0.0000 0.0304 0.0018 0.0658 0.0406 0.1392 0.0689 0.1342 0.0548 0.1519 0.0707 0.4709 0.7633 0.0000 0.0000 0.0020 0.0000 0.0000 0.0000 0.0143 0.0017 0.0369 0.0399 0.0656 0.0624 0.0615 0.0295 0.0820 0.0503 0.7377 0.8163 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0968 0.6364 0.1290 0.1818 0.2796 0.0909 0.1075 0.0909 0.1398 0.0000 0.2473 0.0000 0.0034 0.0068 0.0169 0.0203 0.0811 0.0980 0.0743 0.0845 0.6149 3 4 4 5 5 6 7 7 8 0.0263 7.62 3.939 0.3680 35.5
244.168
1810.28
14316.1
0.5714 0.1153 0.0047 0.0000 0.0712 0.0040 0.1377 0.0160 0.2389 0.0419 0.2358 0.1028 0.2294 0.1766 0.0585 0.2535 0.0190 0.2685 0.0047 0.1367 0.0000 0.0000 0.0154 0.0019 0.0475 0.0065 0.1342 0.0260 0.1853 0.0854 0.2601 0.1365 0.1936 0.2201 0.1211 0.2934 0.0428 0.2303 0.3190 0.5467 0.3667 0.3333 0.1571 0.1067 0.1238 0.0133 0.0286 0.0000 0.0048 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0280 0.1226 0.1559 0.1961 0.2259 0.1471 0.0753 0.0350 0.0140
Hs 578T A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 992 554 image if available 458 453 58.6 18.24 15.98 3.18 38 42 46 52 56 61 66 72 84 0.4040 183 0.735 110.07 27.07 1 0.6135 281 0.0119 5.25 4.713 0.4351 3769.0
265175
20300000
1680000000
0.3546 0.2594 0.0000 0.0000 0.0199 0.0000 0.0448 0.0000 0.0597 0.0052 0.1294 0.0735 0.2139 0.1417 0.1791 0.0761 0.1343 0.1155 0.2189 0.5879 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0164 0.0046 0.0656 0.0371 0.1049 0.0928 0.0721 0.0278 0.0951 0.0603 0.6459 0.7773 0.0096 0.0000 0.0000 0.0000 0.0096 0.0600 0.0673 0.1800 0.2019 0.1000 0.1731 0.2800 0.0865 0.1400 0.1635 0.0600 0.2885 0.1800 0.0000 0.0000 0.0048 0.0335 0.1435 0.1483 0.1100 0.1627 0.3971 12 13 14 15 16 17 17 18 20 0.8738 0.06 0.306 0.9702 265.5
4574.87
81636.7
1510000
0.5349 0.1049 0.0031 0.0000 0.0217 0.0000 0.0683 0.0046 0.1211 0.0207 0.2050 0.1359 0.1739 0.1544 0.1739 0.1613 0.1801 0.1521 0.0528 0.3710 0.0026 0.0000 0.0078 0.0000 0.0284 0.0045 0.0413 0.0089 0.1835 0.1250 0.1550 0.1473 0.1576 0.1518 0.1938 0.1384 0.2300 0.4241 0.2923 0.5000 0.1846 0.2143 0.1385 0.2143 0.1846 0.0714 0.1077 0.0000 0.0615 0.0000 0.0308 0.0000 0.0000 0.0000 0.0000 0.0000 0.0195 0.0586 0.1328 0.1445 0.1758 0.1680 0.1367 0.1055 0.0586