High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 740 | 703 | | 8862 | 18824 | 530.1 | 80.43 | 114.15 | 251.56 | 421 | 467 | 496 | 517 | 535 | 553 | 573 | 598 | 631 | 0.0548 | 1032 | 0.545 | 114.22 | 22.67 | 5 | 0.0372 | 330 | 0.0009 | 38.41 | 7.314 | 0.2073 | 287452.0 | 159000000 | 89500000000 | 51200000000000 | 0.4491 | 0.2025 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0056 | 0.0007 | 0.0282 | 0.0139 | 0.0564 | 0.0200 | 0.0512 | 0.0144 | 0.0715 | 0.0211 | 0.7858 | 0.9298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0016 | 0.0007 | 0.0179 | 0.0139 | 0.0306 | 0.0200 | 0.0252 | 0.0144 | 0.0335 | 0.0202 | 0.8913 | 0.9307 | 0.0075 | 1.0000 | 0.0188 | 0.0000 | 0.0225 | 0.0000 | 0.0476 | 0.0000 | 0.1164 | 0.0000 | 0.1640 | 0.0000 | 0.1014 | 0.0000 | 0.1502 | 0.0000 | 0.3717 | 0.0000 | 0.0006 | 0.0036 | 0.0074 | 0.0181 | 0.0434 | 0.0613 | 0.0734 | 0.0863 | 0.7059 | 9 | 10 | 12 | 13 | 15 | 20 | 38 | 121 | 352 | 0.1429 | 9.00 | 3.049 | 0.5952 | 76308.2 | 79500000 | 99600000000 | 139000000000000 | 0.5235 | 0.1294 | 0.0259 | 0.0023 | 0.0761 | 0.0164 | 0.2120 | 0.0561 | 0.1942 | 0.0865 | 0.2006 | 0.1645 | 0.1003 | 0.2050 | 0.1036 | 0.1458 | 0.0631 | 0.1341 | 0.0243 | 0.1894 | 0.0000 | 0.0004 | 0.0002 | 0.0004 | 0.0012 | 0.0011 | 0.0067 | 0.0072 | 0.0396 | 0.0383 | 0.0538 | 0.0475 | 0.0401 | 0.0385 | 0.0569 | 0.0591 | 0.8015 | 0.8073 | 0.0003 | 0.0000 | 0.0006 | 0.0006 | 0.0017 | 0.0021 | 0.0056 | 0.0079 | 0.0476 | 0.0539 | 0.0673 | 0.0667 | 0.0437 | 0.0521 | 0.0707 | 0.0758 | 0.7625 | 0.7409 | 0.0000 | 0.0005 | 0.0016 | 0.0065 | 0.0428 | 0.0586 | 0.0418 | 0.0664 | 0.7819 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 84 | 350 | | 635 | 11961 | 63.2 | 10.04 | 161.70 | 197.63 | 50 | 54 | 57 | 61 | 63 | 66 | 68 | 71 | 76 | 0.0579 | 693 | 0.875 | 142.76 | 45.97 | 2 | 0.6299 | 400 | 0.0068 | 11.22 | 5.192 | 0.3174 | 4092.7 | 271580 | 18400000 | 1280000000 | 0.4246 | 0.2192 | 0.0020 | 0.0000 | 0.0061 | 0.0016 | 0.0242 | 0.0048 | 0.0364 | 0.0111 | 0.0667 | 0.0430 | 0.1091 | 0.0685 | 0.1172 | 0.0525 | 0.1960 | 0.0812 | 0.4424 | 0.7373 | 0.0018 | 0.0000 | 0.0053 | 0.0016 | 0.0124 | 0.0047 | 0.0284 | 0.0110 | 0.0443 | 0.0379 | 0.0585 | 0.0694 | 0.0709 | 0.0394 | 0.0816 | 0.0599 | 0.6968 | 0.7760 | 0.0580 | 0.3333 | 0.0870 | 0.0000 | 0.1594 | 0.3333 | 0.0725 | 0.3333 | 0.1739 | 0.0000 | 0.0870 | 0.0000 | 0.0580 | 0.0000 | 0.1014 | 0.0000 | 0.2029 | 0.0000 | 0.0060 | 0.0030 | 0.0328 | 0.0448 | 0.0836 | 0.1045 | 0.1104 | 0.1761 | 0.4388 | 14 | 18 | 22 | 31 | 58 | 116 | 205 | 315 | 458 | 0.0352 | 28.43 | 5.403 | 0.4619 | 65200.6 | 35400000 | 22500000000 | 16100000000000 | 0.5927 | 0.1032 | 0.1018 | 0.0034 | 0.2284 | 0.0353 | 0.3243 | 0.1826 | 0.1467 | 0.1894 | 0.1089 | 0.2031 | 0.0462 | 0.1570 | 0.0249 | 0.0990 | 0.0130 | 0.0728 | 0.0059 | 0.0575 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0020 | 0.0022 | 0.0142 | 0.0124 | 0.0583 | 0.0519 | 0.0965 | 0.0944 | 0.0720 | 0.0609 | 0.0991 | 0.0924 | 0.6569 | 0.6855 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0029 | 0.0060 | 0.0195 | 0.0279 | 0.0776 | 0.0835 | 0.1193 | 0.1370 | 0.0921 | 0.0943 | 0.1271 | 0.1346 | 0.5598 | 0.5161 | 0.0002 | 0.0002 | 0.0027 | 0.0176 | 0.0677 | 0.1015 | 0.0832 | 0.1135 | 0.6134 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 937 | 413 | | 5991 | 6903 | 259.1 | 63.26 | 108.57 | 152.78 | 186 | 207 | 223 | 238 | 250 | 265 | 282 | 304 | 342 | 0.1114 | 769 | 0.943 | 112.29 | 28.65 | 1 | 0.0444 | 266 | 0.0008 | 62.88 | 7.417 | 0.1517 | 71152.1 | 20700000 | 6420000000 | 2110000000000 | 0.4321 | 0.2113 | 0.0005 | 0.0000 | 0.0011 | 0.0002 | 0.0030 | 0.0004 | 0.0169 | 0.0024 | 0.0651 | 0.0200 | 0.1350 | 0.0503 | 0.1430 | 0.0444 | 0.1793 | 0.0657 | 0.4560 | 0.8167 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0017 | 0.0002 | 0.0065 | 0.0010 | 0.0301 | 0.0128 | 0.0639 | 0.0298 | 0.0612 | 0.0204 | 0.0850 | 0.0356 | 0.7507 | 0.9002 | 0.0047 | 0.0024 | 0.0084 | 0.0095 | 0.0196 | 0.0261 | 0.0673 | 0.0760 | 0.1047 | 0.1283 | 0.1551 | 0.1995 | 0.1075 | 0.1045 | 0.1299 | 0.1330 | 0.4028 | 0.3207 | 0.0008 | 0.0015 | 0.0094 | 0.0297 | 0.0884 | 0.1290 | 0.1027 | 0.1354 | 0.5032 | 11 | 13 | 15 | 17 | 26 | 49 | 103 | 211 | 341 | 0.0743 | 21.34 | 4.592 | 0.5689 | 35125.6 | 15800000 | 8350000000 | 5000000000000 | 0.6509 | 0.0801 | 0.1317 | 0.0068 | 0.3103 | 0.0476 | 0.2351 | 0.1766 | 0.1505 | 0.1929 | 0.0909 | 0.1984 | 0.0313 | 0.1508 | 0.0313 | 0.0761 | 0.0094 | 0.0788 | 0.0094 | 0.0720 | 0.0023 | 0.0020 | 0.0014 | 0.0020 | 0.0045 | 0.0024 | 0.0136 | 0.0129 | 0.0573 | 0.0488 | 0.0741 | 0.0815 | 0.0605 | 0.0521 | 0.1137 | 0.1013 | 0.6726 | 0.6969 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0023 | 0.0138 | 0.0166 | 0.0585 | 0.0603 | 0.0973 | 0.1194 | 0.0713 | 0.0758 | 0.1176 | 0.1361 | 0.6383 | 0.5896 | 0.0005 | 0.0020 | 0.0030 | 0.0114 | 0.0530 | 0.0956 | 0.0624 | 0.1115 | 0.6606 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 575 | | 6042 | 12072 | 101.1 | 29.15 | 201.53 | 223.69 | 69 | 77 | 84 | 91 | 97 | 103 | 110 | 120 | 139 | 0.0696 | 840 | 0.813 | 79.88 | 25.94 | 1 | 0.0386 | 233 | 0.0015 | 30.07 | 6.806 | 0.2198 | 11069.0 | 1320000 | 170000000 | 23900000000 | 0.4862 | 0.1865 | 0.0018 | 0.0002 | 0.0053 | 0.0006 | 0.0143 | 0.0023 | 0.0289 | 0.0069 | 0.0949 | 0.0296 | 0.1530 | 0.0590 | 0.1434 | 0.0611 | 0.1755 | 0.0846 | 0.3829 | 0.7558 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0005 | 0.0109 | 0.0028 | 0.0454 | 0.0160 | 0.0803 | 0.0329 | 0.0748 | 0.0325 | 0.1071 | 0.0463 | 0.6782 | 0.8690 | 0.0043 | 0.0000 | 0.0017 | 0.0123 | 0.0112 | 0.0334 | 0.0543 | 0.0598 | 0.1422 | 0.1652 | 0.1716 | 0.1845 | 0.1112 | 0.1037 | 0.1362 | 0.1564 | 0.3672 | 0.2847 | 0.0008 | 0.0053 | 0.0162 | 0.0442 | 0.0797 | 0.1330 | 0.1035 | 0.1300 | 0.4873 | 18 | 30 | 47 | 67 | 108 | 171 | 253 | 356 | 517 | 0.0128 | 34.28 | 6.003 | 0.4255 | 90647.1 | 57700000 | 45300000000 | 41800000000000 | 0.5238 | 0.1388 | 0.0299 | 0.0012 | 0.1106 | 0.0112 | 0.2542 | 0.0630 | 0.1719 | 0.1064 | 0.1356 | 0.1694 | 0.1203 | 0.2041 | 0.0759 | 0.1291 | 0.0581 | 0.1283 | 0.0436 | 0.1873 | 0.0002 | 0.0003 | 0.0012 | 0.0009 | 0.0024 | 0.0014 | 0.0120 | 0.0077 | 0.0503 | 0.0456 | 0.0918 | 0.0772 | 0.0637 | 0.0548 | 0.0892 | 0.0894 | 0.6892 | 0.7227 | 0.0008 | 0.0000 | 0.0005 | 0.0016 | 0.0040 | 0.0062 | 0.0171 | 0.0230 | 0.0656 | 0.0792 | 0.1207 | 0.1321 | 0.0874 | 0.0879 | 0.1189 | 0.1252 | 0.5850 | 0.5447 | 0.0005 | 0.0016 | 0.0021 | 0.0115 | 0.0607 | 0.1004 | 0.0736 | 0.1068 | 0.6429 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 814 | | 2851 | 8407 | 391.9 | 153.08 | 40.60 | 64.74 | 211 | 237 | 264 | 302 | 359 | 440 | 510 | 564 | 609 | 0.0793 | 667 | 0.638 | 88.07 | 16.49 | 5 | 0.0831 | 237 | 0.0014 | 33.60 | 6.853 | 0.2650 | 176986.0 | 88700000 | 47600000000 | 26700000000000 | 0.3694 | 0.2467 | 0.0017 | 0.0000 | 0.0000 | 0.0018 | 0.0198 | 0.0037 | 0.0594 | 0.0117 | 0.2228 | 0.0608 | 0.2475 | 0.1148 | 0.1320 | 0.0853 | 0.1254 | 0.1160 | 0.1914 | 0.6059 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0061 | 0.0056 | 0.0386 | 0.0265 | 0.0570 | 0.0521 | 0.0404 | 0.0348 | 0.0545 | 0.0465 | 0.8009 | 0.8341 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0019 | 0.0059 | 0.0049 | 0.0208 | 0.0507 | 0.0639 | 0.0789 | 0.0906 | 0.0478 | 0.0743 | 0.0741 | 0.1055 | 0.7417 | 0.6360 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0430 | 0.0675 | 0.0453 | 0.0606 | 0.7782 | 8 | 10 | 11 | 13 | 15 | 18 | 24 | 42 | 117 | 0.0814 | 2.85 | 3.639 | 0.6573 | 5839.4 | 1330000 | 353000000 | 100000000000 | 0.5410 | 0.1261 | 0.0144 | 0.0101 | 0.0804 | 0.0340 | 0.1835 | 0.0451 | 0.1773 | 0.0975 | 0.1567 | 0.1408 | 0.1649 | 0.1638 | 0.1113 | 0.1408 | 0.0804 | 0.1435 | 0.0309 | 0.2245 | 0.0015 | 0.0040 | 0.0060 | 0.0136 | 0.0144 | 0.0100 | 0.0194 | 0.0244 | 0.0557 | 0.0505 | 0.0815 | 0.0765 | 0.0532 | 0.0589 | 0.0820 | 0.0885 | 0.6864 | 0.6735 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0033 | 0.0050 | 0.0196 | 0.0177 | 0.0629 | 0.0703 | 0.0812 | 0.0809 | 0.0583 | 0.0596 | 0.0799 | 0.0852 | 0.6935 | 0.6806 | 0.0034 | 0.0040 | 0.0017 | 0.0166 | 0.0625 | 0.0763 | 0.0539 | 0.0878 | 0.6936 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1056 | 445 | | 5104 | 5780 | 74.9 | 19.31 | 218.45 | 175.33 | 50 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 100 | 0.1151 | 665 | 0.283 | 207.13 | 44.00 | 2 | 0.1532 | 782 | 0.0025 | 15.54 | 6.261 | 0.2795 | 5985.4 | 506947 | 45300000 | 4250000000 | 0.4661 | 0.1911 | 0.0004 | 0.0002 | 0.0039 | 0.0011 | 0.0191 | 0.0004 | 0.0399 | 0.0051 | 0.1042 | 0.0308 | 0.1402 | 0.0523 | 0.1568 | 0.0660 | 0.1812 | 0.0959 | 0.3543 | 0.7482 | 0.0000 | 0.0002 | 0.0010 | 0.0006 | 0.0066 | 0.0004 | 0.0081 | 0.0019 | 0.0403 | 0.0196 | 0.0608 | 0.0315 | 0.0613 | 0.0313 | 0.0861 | 0.0500 | 0.7359 | 0.8646 | 0.0063 | 0.0116 | 0.0188 | 0.0203 | 0.0385 | 0.0698 | 0.0626 | 0.1221 | 0.1181 | 0.1977 | 0.1503 | 0.1599 | 0.1351 | 0.1279 | 0.1485 | 0.1541 | 0.3220 | 0.1366 | 0.0024 | 0.0020 | 0.0083 | 0.0317 | 0.0797 | 0.1094 | 0.1023 | 0.1380 | 0.5262 | 37 | 65 | 100 | 137 | 174 | 217 | 278 | 349 | 460 | 0.0040 | 34.98 | 6.397 | 0.3275 | 78453.6 | 37400000 | 21600000000 | 14300000000000 | 0.5030 | 0.1632 | 0.0118 | 0.0034 | 0.0686 | 0.0049 | 0.1902 | 0.0303 | 0.1873 | 0.0654 | 0.2000 | 0.1563 | 0.1490 | 0.1904 | 0.0961 | 0.1553 | 0.0696 | 0.1484 | 0.0275 | 0.2456 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0045 | 0.0020 | 0.0170 | 0.0107 | 0.0701 | 0.0457 | 0.1114 | 0.0835 | 0.0947 | 0.0760 | 0.1218 | 0.0998 | 0.5791 | 0.6816 | 0.0000 | 0.0000 | 0.0048 | 0.0039 | 0.0064 | 0.0086 | 0.0301 | 0.0368 | 0.0924 | 0.1092 | 0.1557 | 0.1908 | 0.1090 | 0.1132 | 0.1557 | 0.1586 | 0.4458 | 0.3789 | 0.0009 | 0.0009 | 0.0035 | 0.0242 | 0.0797 | 0.1277 | 0.1035 | 0.1364 | 0.5234 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 312 | 733 | | 7233 | 20217 | 523.9 | 88.32 | 192.73 | 354.08 | 412 | 444 | 470 | 496 | 519 | 544 | 571 | 604 | 641 | 0.0504 | 1018 | 1.154 | 114.98 | 42.58 | 1 | 0.0408 | 295 | 0.0018 | 19.88 | 6.575 | 0.2459 | 282245.0 | 156000000 | 88600000000 | 51500000000000 | 0.4172 | 0.2311 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0003 | 0.0114 | 0.0004 | 0.0461 | 0.0113 | 0.0920 | 0.0228 | 0.1143 | 0.0150 | 0.1514 | 0.0291 | 0.5824 | 0.9210 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0046 | 0.0001 | 0.0219 | 0.0096 | 0.0442 | 0.0195 | 0.0517 | 0.0096 | 0.0720 | 0.0186 | 0.8052 | 0.9427 | 0.0032 | 0.0494 | 0.0085 | 0.0247 | 0.0481 | 0.0617 | 0.1068 | 0.2099 | 0.1474 | 0.1481 | 0.1699 | 0.1728 | 0.1453 | 0.1605 | 0.1271 | 0.1111 | 0.2436 | 0.0617 | 0.0014 | 0.0026 | 0.0072 | 0.0203 | 0.0629 | 0.1090 | 0.0973 | 0.1296 | 0.5697 | 10 | 12 | 14 | 16 | 19 | 32 | 110 | 339 | 644 | 0.1456 | 63.21 | 4.433 | 0.6015 | 162507.0 | 200000000 | 303000000000 | 525000000000000 | 0.5064 | 0.1533 | 0.1318 | 0.0049 | 0.3100 | 0.0323 | 0.3324 | 0.2391 | 0.1234 | 0.2742 | 0.0561 | 0.2167 | 0.0351 | 0.1220 | 0.0042 | 0.0617 | 0.0056 | 0.0358 | 0.0014 | 0.0133 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0005 | 0.0003 | 0.0070 | 0.0065 | 0.0491 | 0.0410 | 0.0772 | 0.0740 | 0.0498 | 0.0478 | 0.0813 | 0.0702 | 0.7351 | 0.7600 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0017 | 0.0119 | 0.0114 | 0.0544 | 0.0623 | 0.0908 | 0.0925 | 0.0634 | 0.0717 | 0.0934 | 0.1071 | 0.6854 | 0.6531 | 0.0000 | 0.0002 | 0.0008 | 0.0084 | 0.0511 | 0.0851 | 0.0532 | 0.0876 | 0.7136 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1271 | 351 | | 4157 | 9898 | 475.9 | 89.44 | 163.26 | 251.77 | 360 | 394 | 423 | 449 | 475 | 498 | 524 | 554 | 594 | 0.0813 | 805 | 1.028 | 152.20 | 40.79 | 2 | 0.0871 | 362 | 0.0008 | 73.60 | 7.318 | 0.1483 | 234454.0 | 119000000 | 62600000000 | 33700000000000 | 0.4174 | 0.2233 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0017 | 0.0000 | 0.0196 | 0.0010 | 0.0716 | 0.0187 | 0.1191 | 0.0382 | 0.1160 | 0.0296 | 0.1725 | 0.0500 | 0.4981 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0069 | 0.0007 | 0.0343 | 0.0162 | 0.0480 | 0.0300 | 0.0474 | 0.0157 | 0.0809 | 0.0288 | 0.7811 | 0.9086 | 0.0000 | 0.0390 | 0.0204 | 0.0260 | 0.0471 | 0.1429 | 0.0973 | 0.2597 | 0.1476 | 0.2338 | 0.2057 | 0.1558 | 0.1350 | 0.0779 | 0.1162 | 0.0519 | 0.2308 | 0.0130 | 0.0010 | 0.0010 | 0.0048 | 0.0299 | 0.0676 | 0.1356 | 0.1236 | 0.1472 | 0.4894 | 7 | 10 | 13 | 22 | 39 | 75 | 136 | 293 | 547 | 0.0676 | 32.18 | 4.895 | 0.5343 | 90034.8 | 69000000 | 62100000000 | 62700000000000 | 0.5861 | 0.0893 | 0.0409 | 0.0025 | 0.1595 | 0.0187 | 0.2704 | 0.0934 | 0.2179 | 0.1214 | 0.1595 | 0.1766 | 0.0914 | 0.2054 | 0.0311 | 0.1350 | 0.0214 | 0.1180 | 0.0078 | 0.1290 | 0.0003 | 0.0003 | 0.0013 | 0.0017 | 0.0043 | 0.0049 | 0.0140 | 0.0129 | 0.0478 | 0.0466 | 0.0870 | 0.0765 | 0.0558 | 0.0552 | 0.0797 | 0.0797 | 0.7096 | 0.7222 | 0.0004 | 0.0000 | 0.0016 | 0.0017 | 0.0028 | 0.0043 | 0.0172 | 0.0170 | 0.0537 | 0.0679 | 0.1034 | 0.0909 | 0.0577 | 0.0635 | 0.0885 | 0.0905 | 0.6747 | 0.6642 | 0.0000 | 0.0026 | 0.0026 | 0.0125 | 0.0521 | 0.0922 | 0.0558 | 0.0845 | 0.6978 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1098 | 496 | | 1949 | 1938 | 124.8 | 50.11 | 251.47 | 187.75 | 64 | 82 | 94 | 105 | 119 | 134 | 149 | 168 | 192 | 0.1858 | 360 | 0.821 | 96.77 | 26.42 | 1 | 0.1442 | 281 | 0.0008 | 114.59 | 7.204 | 0.1050 | 18080.3 | 2940000 | 523000000 | 100000000000 | 0.5094 | 0.1519 | 0.0015 | 0.0000 | 0.0073 | 0.0000 | 0.0601 | 0.0008 | 0.1246 | 0.0061 | 0.2463 | 0.0736 | 0.2625 | 0.1753 | 0.1540 | 0.1578 | 0.0748 | 0.1700 | 0.0689 | 0.4165 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0103 | 0.0036 | 0.0745 | 0.0379 | 0.1149 | 0.0752 | 0.0745 | 0.0578 | 0.1117 | 0.0848 | 0.6117 | 0.7407 | 0.0000 | 0.0000 | 0.0052 | 0.0058 | 0.0086 | 0.0116 | 0.0448 | 0.0785 | 0.1345 | 0.2006 | 0.2103 | 0.2209 | 0.0845 | 0.0930 | 0.1379 | 0.1483 | 0.3741 | 0.2413 | 0.0000 | 0.0022 | 0.0078 | 0.0201 | 0.0983 | 0.1497 | 0.0927 | 0.1352 | 0.4939 | 69 | 95 | 125 | 160 | 191 | 236 | 305 | 403 | 529 | 0.0029 | 36.15 | 6.309 | 0.2943 | 98467.7 | 51400000 | 32500000000 | 23600000000000 | 0.4492 | 0.1782 | 0.0235 | 0.0014 | 0.0882 | 0.0096 | 0.2235 | 0.0193 | 0.1559 | 0.0674 | 0.1500 | 0.1747 | 0.1118 | 0.1678 | 0.0941 | 0.1307 | 0.0735 | 0.1321 | 0.0794 | 0.2971 | 0.0022 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0033 | 0.0194 | 0.0124 | 0.0809 | 0.0521 | 0.1143 | 0.0884 | 0.0895 | 0.0711 | 0.1219 | 0.1207 | 0.5674 | 0.6521 | 0.0000 | 0.0000 | 0.0085 | 0.0083 | 0.0085 | 0.0145 | 0.0341 | 0.0311 | 0.0937 | 0.1284 | 0.1312 | 0.1139 | 0.1039 | 0.0911 | 0.1039 | 0.1304 | 0.5162 | 0.4824 | 0.0000 | 0.0027 | 0.0000 | 0.0396 | 0.0723 | 0.1432 | 0.0900 | 0.1050 | 0.5471 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 527 | 515 | | 5715 | 12689 | 251.9 | 56.62 | 150.62 | 209.22 | 183 | 202 | 219 | 233 | 247 | 260 | 276 | 297 | 331 | 0.0632 | 802 | 1.048 | 109.64 | 33.14 | 1 | 0.0469 | 268 | 0.0008 | 63.76 | 7.408 | 0.1534 | 66641.6 | 18500000 | 5370000000 | 1630000000000 | 0.4360 | 0.2148 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0025 | 0.0002 | 0.0187 | 0.0025 | 0.0696 | 0.0238 | 0.1504 | 0.0429 | 0.1390 | 0.0489 | 0.1636 | 0.0736 | 0.4555 | 0.8082 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0002 | 0.0059 | 0.0005 | 0.0317 | 0.0144 | 0.0696 | 0.0231 | 0.0635 | 0.0224 | 0.0854 | 0.0339 | 0.7433 | 0.9055 | 0.0039 | 0.0090 | 0.0117 | 0.0180 | 0.0098 | 0.0689 | 0.0615 | 0.1377 | 0.1200 | 0.1707 | 0.1698 | 0.2006 | 0.1307 | 0.1257 | 0.1512 | 0.1168 | 0.3415 | 0.1527 | 0.0004 | 0.0038 | 0.0072 | 0.0249 | 0.0879 | 0.1271 | 0.1094 | 0.1309 | 0.5085 | 13 | 16 | 20 | 28 | 50 | 82 | 128 | 280 | 472 | 0.0397 | 26.37 | 5.194 | 0.5314 | 66455.3 | 40900000 | 29300000000 | 23200000000000 | 0.6051 | 0.0829 | 0.0898 | 0.0028 | 0.1918 | 0.0158 | 0.2116 | 0.1088 | 0.1233 | 0.1172 | 0.1218 | 0.1714 | 0.1233 | 0.1426 | 0.0502 | 0.0857 | 0.0548 | 0.1144 | 0.0335 | 0.2413 | 0.0015 | 0.0000 | 0.0020 | 0.0002 | 0.0046 | 0.0019 | 0.0130 | 0.0093 | 0.0490 | 0.0542 | 0.0785 | 0.0762 | 0.0554 | 0.0529 | 0.0773 | 0.0855 | 0.7187 | 0.7197 | 0.0003 | 0.0000 | 0.0003 | 0.0007 | 0.0015 | 0.0007 | 0.0079 | 0.0102 | 0.0580 | 0.0565 | 0.0827 | 0.0953 | 0.0638 | 0.0723 | 0.0958 | 0.1029 | 0.6898 | 0.6614 | 0.0006 | 0.0003 | 0.0017 | 0.0073 | 0.0525 | 0.0797 | 0.0581 | 0.0850 | 0.7149 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1251 | 214 | | 356 | 5823 | 35.2 | 7.41 | 113.18 | 175.08 | 27 | 29 | 30 | 32 | 34 | 37 | 39 | 42 | 46 | 0.0792 | 461 | 0.420 | 101.19 | 15.26 | 1 | 0.8736 | 311 | 0.0113 | 6.98 | 4.700 | 0.3318 | 1292.1 | 49511.8 | 1970000 | 81800000 | 0.4112 | 0.2070 | 0.0000 | 0.0000 | 0.0044 | 0.0000 | 0.0439 | 0.0000 | 0.0877 | 0.0118 | 0.1711 | 0.0708 | 0.1798 | 0.0678 | 0.2719 | 0.1121 | 0.1491 | 0.1563 | 0.0921 | 0.5811 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0000 | 0.0261 | 0.0113 | 0.0554 | 0.0592 | 0.0782 | 0.0563 | 0.1401 | 0.0676 | 0.1759 | 0.0901 | 0.5049 | 0.7155 | 0.0127 | 0.0625 | 0.0000 | 0.1250 | 0.0759 | 0.0625 | 0.2532 | 0.2500 | 0.1646 | 0.1250 | 0.1772 | 0.1875 | 0.1139 | 0.1250 | 0.1013 | 0.0625 | 0.1013 | 0.0000 | 0.0000 | 0.0242 | 0.0424 | 0.0667 | 0.1030 | 0.1576 | 0.1455 | 0.1636 | 0.2970 | 16 | 20 | 25 | 33 | 45 | 68 | 103 | 161 | 264 | 0.0724 | 6.00 | 4.044 | 0.6522 | 43457.4 | 30200000 | 26300000000 | 25200000000000 | 0.6089 | 0.0954 | 0.0138 | 0.0044 | 0.0881 | 0.0044 | 0.1796 | 0.0413 | 0.1503 | 0.0739 | 0.1658 | 0.1706 | 0.1330 | 0.1715 | 0.1278 | 0.1407 | 0.0950 | 0.1416 | 0.0466 | 0.2515 | 0.0000 | 0.0009 | 0.0015 | 0.0004 | 0.0041 | 0.0017 | 0.0164 | 0.0133 | 0.0590 | 0.0506 | 0.0878 | 0.0665 | 0.0678 | 0.0545 | 0.0965 | 0.0982 | 0.6668 | 0.7139 | 0.0015 | 0.0000 | 0.0015 | 0.0017 | 0.0037 | 0.0050 | 0.0161 | 0.0209 | 0.0701 | 0.0771 | 0.1103 | 0.1131 | 0.0621 | 0.0737 | 0.1169 | 0.1307 | 0.6180 | 0.5779 | 0.0006 | 0.0031 | 0.0043 | 0.0210 | 0.0611 | 0.0945 | 0.0667 | 0.1050 | 0.6436 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 986 | 375 | | 3412 | 6862 | 481.9 | 117.20 | 93.02 | 146.48 | 305 | 387 | 443 | 490 | 520 | 538 | 554 | 572 | 596 | 0.0851 | 584 | 0.932 | 72.01 | 24.21 | 1 | 0.0592 | 202 | 0.0011 | 37.12 | 7.131 | 0.2177 | 245995.0 | 130000000 | 70600000000 | 39000000000000 | 0.3975 | 0.2313 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0153 | 0.0006 | 0.0384 | 0.0161 | 0.0685 | 0.0274 | 0.0782 | 0.0187 | 0.1319 | 0.0332 | 0.6645 | 0.9040 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0179 | 0.0160 | 0.0285 | 0.0249 | 0.0223 | 0.0150 | 0.0347 | 0.0278 | 0.8936 | 0.9159 | 0.0209 | 0.0435 | 0.0104 | 0.0000 | 0.0330 | 0.0000 | 0.0557 | 0.0435 | 0.0783 | 0.3478 | 0.0870 | 0.1739 | 0.0991 | 0.0000 | 0.1113 | 0.3043 | 0.5043 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0247 | 0.0451 | 0.0400 | 0.0679 | 0.8162 | 10 | 13 | 16 | 21 | 27 | 40 | 68 | 138 | 287 | 0.0426 | 28.93 | 4.699 | 0.5709 | 30108.0 | 15300000 | 9600000000 | 6980000000000 | 0.4972 | 0.1660 | 0.0636 | 0.0056 | 0.1051 | 0.0237 | 0.0954 | 0.0847 | 0.1345 | 0.0790 | 0.1614 | 0.0926 | 0.1809 | 0.1400 | 0.1394 | 0.1264 | 0.0831 | 0.1072 | 0.0367 | 0.3409 | 0.0005 | 0.0013 | 0.0005 | 0.0017 | 0.0036 | 0.0031 | 0.0180 | 0.0144 | 0.0598 | 0.0423 | 0.0721 | 0.0737 | 0.0562 | 0.0471 | 0.0814 | 0.0702 | 0.7079 | 0.7462 | 0.0013 | 0.0000 | 0.0020 | 0.0007 | 0.0007 | 0.0000 | 0.0196 | 0.0156 | 0.0607 | 0.0675 | 0.0881 | 0.0896 | 0.0529 | 0.0490 | 0.0783 | 0.0888 | 0.6965 | 0.6887 | 0.0012 | 0.0012 | 0.0029 | 0.0175 | 0.0544 | 0.0807 | 0.0526 | 0.0807 | 0.7089 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 652 | 166 | | 1359 | 6119 | 428.9 | 60.31 | 32.37 | 70.62 | 351 | 373 | 390 | 405 | 426 | 446 | 465 | 483 | 508 | 0.0709 | 434 | 0.794 | 97.08 | 19.70 | 1 | 0.1670 | 227 | 0.0023 | 22.07 | 6.272 | 0.2405 | 187585.0 | 83600000 | 38000000000 | 17500000000000 | 0.4204 | 0.2216 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0061 | 0.0000 | 0.0462 | 0.0221 | 0.0688 | 0.0324 | 0.0592 | 0.0191 | 0.0897 | 0.0316 | 0.7265 | 0.8948 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0016 | 0.0000 | 0.0293 | 0.0221 | 0.0443 | 0.0324 | 0.0332 | 0.0191 | 0.0546 | 0.0316 | 0.8347 | 0.8948 | 0.0259 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0776 | 0.0000 | 0.1638 | 0.0000 | 0.1983 | 0.0000 | 0.1207 | 0.0000 | 0.1379 | 0.0000 | 0.2759 | 0.0000 | 0.0000 | 0.0046 | 0.0077 | 0.0107 | 0.0475 | 0.0644 | 0.0706 | 0.0982 | 0.6963 | 6 | 8 | 9 | 10 | 11 | 13 | 15 | 23 | 79 | 0.3514 | 3.58 | 2.313 | 0.8106 | 6034.5 | 2460000 | 1350000000 | 863000000000 | 0.6003 | 0.1052 | 0.0807 | 0.0227 | 0.0807 | 0.0644 | 0.1211 | 0.0814 | 0.2870 | 0.1458 | 0.1435 | 0.1496 | 0.1480 | 0.1458 | 0.0762 | 0.1326 | 0.0583 | 0.1307 | 0.0045 | 0.1269 | 0.0088 | 0.0079 | 0.0044 | 0.0186 | 0.0071 | 0.0193 | 0.0274 | 0.0336 | 0.0398 | 0.0480 | 0.0548 | 0.0523 | 0.0610 | 0.0651 | 0.0839 | 0.0938 | 0.7129 | 0.6614 | 0.0000 | 0.0000 | 0.0044 | 0.0023 | 0.0055 | 0.0046 | 0.0143 | 0.0161 | 0.0539 | 0.0506 | 0.0462 | 0.0598 | 0.0616 | 0.0529 | 0.0935 | 0.0978 | 0.7206 | 0.7158 | 0.0020 | 0.0050 | 0.0090 | 0.0160 | 0.0548 | 0.0439 | 0.0499 | 0.1017 | 0.7178 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 140 | | 4015 | 11442 | 298.5 | 93.89 | 283.49 | 327.91 | 188 | 224 | 248 | 270 | 290 | 313 | 337 | 371 | 423 | 0.0718 | 821 | 0.641 | 110.89 | 16.16 | 3 | 0.0590 | 237 | 0.0005 | 119.77 | 7.721 | 0.1137 | 97912.3 | 34900000 | 13400000000 | 5490000000000 | 0.4228 | 0.1994 | 0.0000 | 0.0000 | 0.0005 | 0.0003 | 0.0078 | 0.0000 | 0.0352 | 0.0049 | 0.0906 | 0.0391 | 0.1684 | 0.0564 | 0.1361 | 0.0524 | 0.1522 | 0.0795 | 0.4092 | 0.7675 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0135 | 0.0016 | 0.0347 | 0.0237 | 0.0663 | 0.0307 | 0.0579 | 0.0234 | 0.0710 | 0.0373 | 0.7547 | 0.8833 | 0.0011 | 0.0093 | 0.0032 | 0.0023 | 0.0086 | 0.0163 | 0.0452 | 0.0629 | 0.0893 | 0.0979 | 0.1453 | 0.1375 | 0.0969 | 0.1235 | 0.1163 | 0.1142 | 0.4941 | 0.4359 | 0.0005 | 0.0005 | 0.0032 | 0.0244 | 0.0684 | 0.1087 | 0.0976 | 0.1124 | 0.5843 | 18 | 23 | 31 | 69 | 150 | 246 | 370 | 532 | 762 | 0.0260 | 64.88 | 6.232 | 0.4074 | 187886.0 | 166000000 | 173000000000 | 201000000000000 | 0.6183 | 0.1150 | 0.0315 | 0.0018 | 0.0954 | 0.0093 | 0.2028 | 0.0466 | 0.1778 | 0.0888 | 0.1759 | 0.1607 | 0.1389 | 0.1793 | 0.0880 | 0.1474 | 0.0528 | 0.1482 | 0.0370 | 0.2179 | 0.0008 | 0.0000 | 0.0015 | 0.0004 | 0.0054 | 0.0022 | 0.0149 | 0.0104 | 0.0492 | 0.0440 | 0.0677 | 0.0593 | 0.0620 | 0.0557 | 0.0989 | 0.0825 | 0.6996 | 0.7454 | 0.0014 | 0.0000 | 0.0038 | 0.0019 | 0.0049 | 0.0074 | 0.0181 | 0.0211 | 0.0585 | 0.0692 | 0.0937 | 0.0977 | 0.0766 | 0.0922 | 0.1110 | 0.1151 | 0.6320 | 0.5954 | 0.0005 | 0.0026 | 0.0062 | 0.0133 | 0.0554 | 0.0778 | 0.0700 | 0.1011 | 0.6730 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 474 | 145 | | 2157 | 11213 | 221.6 | 78.59 | 65.05 | 137.53 | 132 | 156 | 176 | 192 | 207 | 222 | 245 | 295 | 349 | 0.0538 | 603 | 0.725 | 94.64 | 21.02 | 1 | 0.1136 | 245 | 0.0010 | 66.86 | 7.099 | 0.1610 | 55259.5 | 15300000 | 4580000000 | 1470000000000 | 0.4001 | 0.2354 | 0.0011 | 0.0000 | 0.0000 | 0.0013 | 0.0064 | 0.0032 | 0.0416 | 0.0121 | 0.0928 | 0.0490 | 0.1738 | 0.0732 | 0.1525 | 0.0803 | 0.1514 | 0.0968 | 0.3806 | 0.6841 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0027 | 0.0010 | 0.0148 | 0.0073 | 0.0425 | 0.0250 | 0.0748 | 0.0374 | 0.0742 | 0.0421 | 0.0883 | 0.0525 | 0.7026 | 0.8341 | 0.0055 | 0.0028 | 0.0037 | 0.0000 | 0.0073 | 0.0085 | 0.0147 | 0.0312 | 0.0569 | 0.0708 | 0.0734 | 0.1246 | 0.0477 | 0.1161 | 0.0734 | 0.1161 | 0.7174 | 0.5297 | 0.0000 | 0.0092 | 0.0035 | 0.0403 | 0.0909 | 0.0967 | 0.0748 | 0.0748 | 0.6099 | 12 | 14 | 15 | 17 | 18 | 20 | 25 | 45 | 176 | 0.1489 | 17.64 | 3.226 | 0.6746 | 23145.6 | 15600000 | 14100000000 | 15200000000000 | 0.6928 | 0.0672 | 0.0631 | 0.0192 | 0.1329 | 0.0266 | 0.2691 | 0.0932 | 0.2060 | 0.1391 | 0.1761 | 0.1953 | 0.1030 | 0.1982 | 0.0399 | 0.1450 | 0.0100 | 0.1109 | 0.0000 | 0.0725 | 0.0000 | 0.0037 | 0.0009 | 0.0029 | 0.0023 | 0.0054 | 0.0089 | 0.0125 | 0.0455 | 0.0432 | 0.0829 | 0.0602 | 0.0590 | 0.0557 | 0.0890 | 0.0798 | 0.7113 | 0.7366 | 0.0000 | 0.0000 | 0.0005 | 0.0006 | 0.0016 | 0.0023 | 0.0104 | 0.0116 | 0.0595 | 0.0687 | 0.1075 | 0.1167 | 0.0797 | 0.0797 | 0.1151 | 0.1358 | 0.6258 | 0.5846 | 0.0000 | 0.0010 | 0.0005 | 0.0090 | 0.0562 | 0.0853 | 0.0693 | 0.1094 | 0.6692 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 524 | 141 | | 4317 | 6246 | 463.8 | 114.50 | 71.69 | 106.41 | 339 | 369 | 392 | 415 | 440 | 467 | 500 | 549 | 629 | 0.1005 | 628 | 1.211 | 95.02 | 37.48 | 1 | 0.0563 | 243 | 0.0011 | 40.02 | 7.058 | 0.1884 | 228193.0 | 119000000 | 66600000000 | 39500000000000 | 0.3905 | 0.2504 | 0.0000 | 0.0000 | 0.0012 | 0.0005 | 0.0054 | 0.0005 | 0.0173 | 0.0033 | 0.0695 | 0.0228 | 0.1245 | 0.0415 | 0.1318 | 0.0400 | 0.1690 | 0.0488 | 0.4814 | 0.8426 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0076 | 0.0009 | 0.0334 | 0.0140 | 0.0577 | 0.0244 | 0.0633 | 0.0147 | 0.0882 | 0.0216 | 0.7466 | 0.9244 | 0.0037 | 0.0000 | 0.0049 | 0.0057 | 0.0099 | 0.0345 | 0.0469 | 0.0690 | 0.0877 | 0.1293 | 0.1395 | 0.1264 | 0.1025 | 0.1264 | 0.1173 | 0.1494 | 0.4877 | 0.3592 | 0.0006 | 0.0051 | 0.0130 | 0.0395 | 0.0745 | 0.1072 | 0.0874 | 0.0987 | 0.5742 | 7 | 10 | 12 | 15 | 21 | 31 | 56 | 127 | 227 | 0.0902 | 12.13 | 4.224 | 0.6055 | 16459.4 | 5640000 | 2380000000 | 1160000000000 | 0.4828 | 0.1513 | 0.0532 | 0.0047 | 0.1894 | 0.0235 | 0.2990 | 0.0691 | 0.2359 | 0.1821 | 0.1196 | 0.2323 | 0.0698 | 0.2276 | 0.0266 | 0.1366 | 0.0000 | 0.0754 | 0.0066 | 0.0487 | 0.0000 | 0.0014 | 0.0000 | 0.0014 | 0.0022 | 0.0039 | 0.0129 | 0.0082 | 0.0533 | 0.0488 | 0.0787 | 0.0768 | 0.0566 | 0.0497 | 0.0981 | 0.0888 | 0.6983 | 0.7209 | 0.0000 | 0.0000 | 0.0013 | 0.0021 | 0.0058 | 0.0077 | 0.0154 | 0.0112 | 0.0624 | 0.0732 | 0.0977 | 0.0962 | 0.0585 | 0.0635 | 0.1145 | 0.1123 | 0.6444 | 0.6339 | 0.0000 | 0.0018 | 0.0035 | 0.0183 | 0.0589 | 0.0796 | 0.0654 | 0.0961 | 0.6765 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1212 | 580 | | 1103 | 14618 | 561.7 | 138.16 | 35.88 | 63.16 | 370 | 419 | 468 | 517 | 560 | 608 | 658 | 706 | 751 | 0.0501 | 732 | 0.997 | 49.98 | 12.04 | 3 | 0.1024 | 113 | 0.0028 | 12.27 | 6.069 | 0.2960 | 334620.0 | 209000000 | 136000000000 | 91500000000000 | 0.3419 | 0.2943 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.0000 | 0.0170 | 0.0039 | 0.0679 | 0.0309 | 0.1434 | 0.0588 | 0.0830 | 0.0366 | 0.1264 | 0.0723 | 0.5566 | 0.7975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0049 | 0.0019 | 0.0317 | 0.0272 | 0.0537 | 0.0497 | 0.0305 | 0.0244 | 0.0464 | 0.0384 | 0.8327 | 0.8585 | 0.0035 | 0.0667 | 0.0035 | 0.1000 | 0.0069 | 0.0667 | 0.0277 | 0.0667 | 0.0415 | 0.1667 | 0.1073 | 0.1667 | 0.0415 | 0.1000 | 0.0484 | 0.1333 | 0.7197 | 0.1333 | 0.0000 | 0.0000 | 0.0037 | 0.0147 | 0.0367 | 0.0606 | 0.0495 | 0.0495 | 0.7853 | 5 | 6 | 8 | 9 | 10 | 12 | 16 | 40 | 115 | 0.1429 | 1.10 | 2.444 | 0.5930 | 5276.5 | 1200000 | 317000000 | 92500000000 | 0.4895 | 0.1637 | 0.0684 | 0.0063 | 0.2928 | 0.0125 | 0.3403 | 0.0859 | 0.1521 | 0.2560 | 0.0665 | 0.3196 | 0.0418 | 0.1674 | 0.0209 | 0.0859 | 0.0114 | 0.0358 | 0.0057 | 0.0304 | 0.0003 | 0.0008 | 0.0006 | 0.0013 | 0.0015 | 0.0043 | 0.0150 | 0.0179 | 0.0479 | 0.0415 | 0.0814 | 0.0672 | 0.0568 | 0.0573 | 0.0912 | 0.0851 | 0.7054 | 0.7246 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0043 | 0.0011 | 0.0149 | 0.0164 | 0.0532 | 0.0611 | 0.0987 | 0.1019 | 0.0664 | 0.0710 | 0.1015 | 0.1111 | 0.6610 | 0.6366 | 0.0000 | 0.0003 | 0.0036 | 0.0098 | 0.0577 | 0.0925 | 0.0584 | 0.1013 | 0.6764 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 900 | 171 | | 3930 | 11298 | 497.7 | 103.96 | 94.40 | 173.19 | 316 | 409 | 476 | 500 | 521 | 540 | 560 | 583 | 613 | 0.0641 | 724 | 0.847 | 112.54 | 33.02 | 4 | 0.0832 | 327 | 0.0011 | 32.58 | 7.096 | 0.2211 | 258499.0 | 139000000 | 76000000000 | 42400000000000 | 0.3874 | 0.2511 | 0.0008 | 0.0003 | 0.0015 | 0.0000 | 0.0057 | 0.0000 | 0.0069 | 0.0008 | 0.0413 | 0.0186 | 0.0462 | 0.0251 | 0.0569 | 0.0178 | 0.0810 | 0.0276 | 0.7597 | 0.9099 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0197 | 0.0186 | 0.0188 | 0.0251 | 0.0172 | 0.0178 | 0.0260 | 0.0276 | 0.9179 | 0.9099 | 0.0052 | 0.0000 | 0.0140 | 0.0000 | 0.0315 | 0.0000 | 0.0542 | 0.0000 | 0.0717 | 0.0000 | 0.0944 | 0.0000 | 0.1119 | 0.0000 | 0.1556 | 0.0000 | 0.4615 | 0.0000 | 0.0012 | 0.0042 | 0.0037 | 0.0108 | 0.0279 | 0.0396 | 0.0500 | 0.0629 | 0.7997 | 6 | 7 | 9 | 10 | 14 | 24 | 52 | 125 | 339 | 0.1266 | 21.37 | 4.235 | 0.6154 | 38902.8 | 22700000 | 15400000000 | 11500000000000 | 0.5106 | 0.1373 | 0.0416 | 0.0018 | 0.1323 | 0.0210 | 0.2420 | 0.0602 | 0.1739 | 0.1267 | 0.1815 | 0.2124 | 0.1361 | 0.2042 | 0.0586 | 0.1258 | 0.0265 | 0.1167 | 0.0076 | 0.1313 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0031 | 0.0015 | 0.0097 | 0.0106 | 0.0497 | 0.0439 | 0.0660 | 0.0569 | 0.0453 | 0.0375 | 0.0729 | 0.0623 | 0.7530 | 0.7860 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0018 | 0.0139 | 0.0172 | 0.0499 | 0.0548 | 0.0820 | 0.0743 | 0.0465 | 0.0535 | 0.0714 | 0.0729 | 0.7342 | 0.7254 | 0.0008 | 0.0000 | 0.0015 | 0.0131 | 0.0528 | 0.0670 | 0.0466 | 0.0751 | 0.7432 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 826 | 707 | | 7372 | 21148 | 252.5 | 53.79 | 169.89 | 208.84 | 187 | 203 | 217 | 232 | 247 | 263 | 279 | 299 | 324 | 0.0440 | 931 | 0.980 | 86.83 | 30.02 | 1 | 0.0311 | 229 | 0.0008 | 53.24 | 7.330 | 0.1651 | 66652.7 | 18400000 | 5290000000 | 1590000000000 | 0.4618 | 0.1983 | 0.0000 | 0.0000 | 0.0015 | 0.0001 | 0.0048 | 0.0000 | 0.0231 | 0.0016 | 0.0808 | 0.0131 | 0.1549 | 0.0265 | 0.1579 | 0.0260 | 0.1862 | 0.0450 | 0.3908 | 0.8876 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0101 | 0.0005 | 0.0353 | 0.0083 | 0.0679 | 0.0166 | 0.0713 | 0.0101 | 0.0901 | 0.0194 | 0.7234 | 0.9451 | 0.0023 | 0.0073 | 0.0083 | 0.0366 | 0.0264 | 0.0623 | 0.0746 | 0.1282 | 0.1432 | 0.1758 | 0.1907 | 0.1319 | 0.1311 | 0.1575 | 0.1409 | 0.0989 | 0.2826 | 0.2015 | 0.0003 | 0.0044 | 0.0075 | 0.0232 | 0.0786 | 0.1193 | 0.0987 | 0.1425 | 0.5255 | 10 | 12 | 15 | 27 | 67 | 141 | 237 | 331 | 459 | 0.0738 | 28.37 | 5.373 | 0.4963 | 72475.9 | 42400000 | 31000000000 | 26900000000000 | 0.4734 | 0.1923 | 0.0494 | 0.0029 | 0.2224 | 0.0070 | 0.3468 | 0.1140 | 0.1622 | 0.2051 | 0.0962 | 0.2533 | 0.0622 | 0.2019 | 0.0327 | 0.0889 | 0.0186 | 0.0625 | 0.0096 | 0.0644 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0070 | 0.0057 | 0.0424 | 0.0396 | 0.0866 | 0.0755 | 0.0557 | 0.0466 | 0.0794 | 0.0711 | 0.7274 | 0.7607 | 0.0001 | 0.0000 | 0.0007 | 0.0005 | 0.0014 | 0.0028 | 0.0130 | 0.0161 | 0.0580 | 0.0627 | 0.1058 | 0.1260 | 0.0772 | 0.0841 | 0.1033 | 0.1156 | 0.6404 | 0.5922 | 0.0000 | 0.0009 | 0.0017 | 0.0096 | 0.0496 | 0.0965 | 0.0657 | 0.0897 | 0.6863 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1042 | 789 | | 4633 | 3947 | 309.0 | 85.58 | 54.10 | 75.99 | 211 | 234 | 254 | 275 | 297 | 321 | 347 | 379 | 425 | 0.1416 | 559 | 1.223 | 113.14 | 42.72 | 2 | 0.0611 | 283 | 0.0011 | 39.29 | 7.071 | 0.1920 | 102831.0 | 36800000 | 14100000000 | 5740000000000 | 0.4077 | 0.2400 | 0.0025 | 0.0000 | 0.0017 | 0.0000 | 0.0096 | 0.0010 | 0.0347 | 0.0042 | 0.0967 | 0.0272 | 0.1590 | 0.0589 | 0.1695 | 0.0641 | 0.1720 | 0.0809 | 0.3544 | 0.7637 | 0.0015 | 0.0000 | 0.0012 | 0.0000 | 0.0038 | 0.0002 | 0.0108 | 0.0025 | 0.0349 | 0.0155 | 0.0578 | 0.0314 | 0.0624 | 0.0285 | 0.0789 | 0.0390 | 0.7488 | 0.8829 | 0.0020 | 0.0072 | 0.0029 | 0.0048 | 0.0255 | 0.0240 | 0.0617 | 0.0983 | 0.1126 | 0.1535 | 0.1675 | 0.1942 | 0.1097 | 0.1127 | 0.1185 | 0.1439 | 0.3996 | 0.2614 | 0.0000 | 0.0019 | 0.0071 | 0.0243 | 0.0689 | 0.1189 | 0.0946 | 0.1151 | 0.5692 | 5 | 7 | 9 | 14 | 22 | 33 | 51 | 84 | 152 | 0.0668 | 2.00 | 3.739 | 0.6395 | 8700.0 | 2130000 | 626000000 | 203000000000 | 0.6000 | 0.0806 | 0.0176 | 0.0083 | 0.0941 | 0.0180 | 0.1294 | 0.0319 | 0.1382 | 0.0610 | 0.2382 | 0.1290 | 0.1735 | 0.1817 | 0.1147 | 0.1637 | 0.0676 | 0.1484 | 0.0265 | 0.2580 | 0.0000 | 0.0038 | 0.0045 | 0.0044 | 0.0105 | 0.0044 | 0.0225 | 0.0145 | 0.0495 | 0.0415 | 0.0623 | 0.0629 | 0.0705 | 0.0585 | 0.0990 | 0.0938 | 0.6812 | 0.7162 | 0.0020 | 0.0000 | 0.0050 | 0.0012 | 0.0070 | 0.0104 | 0.0232 | 0.0207 | 0.0524 | 0.0622 | 0.0866 | 0.0956 | 0.0725 | 0.0634 | 0.0987 | 0.1002 | 0.6526 | 0.6463 | 0.0017 | 0.0017 | 0.0104 | 0.0200 | 0.0564 | 0.0720 | 0.0764 | 0.0911 | 0.6701 |