High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1274 | 376 | | 2281 | 2786 | 112.4 | 25.36 | 148.51 | 132.43 | 87 | 92 | 97 | 102 | 107 | 112 | 119 | 128 | 147 | 0.1637 | 456 | 1.143 | 80.71 | 26.48 | 1 | 0.0886 | 202 | 0.0048 | 13.65 | 5.717 | 0.3134 | 13272.8 | 1660000 | 220000000 | 31200000000 | 0.3671 | 0.2788 | 0.0013 | 0.0000 | 0.0019 | 0.0000 | 0.0126 | 0.0000 | 0.0265 | 0.0028 | 0.0670 | 0.0317 | 0.1062 | 0.0602 | 0.1207 | 0.0417 | 0.1903 | 0.0677 | 0.4735 | 0.7958 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0083 | 0.0000 | 0.0129 | 0.0013 | 0.0326 | 0.0193 | 0.0625 | 0.0408 | 0.0641 | 0.0171 | 0.1013 | 0.0289 | 0.7163 | 0.8926 | 0.0085 | 0.0000 | 0.0170 | 0.0176 | 0.0255 | 0.0353 | 0.0595 | 0.1000 | 0.1360 | 0.1294 | 0.1105 | 0.1471 | 0.1133 | 0.1647 | 0.1586 | 0.1353 | 0.3711 | 0.2706 | 0.0044 | 0.0065 | 0.0153 | 0.0513 | 0.0938 | 0.1134 | 0.1080 | 0.1363 | 0.4711 | 14 | 25 | 51 | 80 | 114 | 151 | 191 | 253 | 347 | 0.0074 | 29.86 | 6.106 | 0.3653 | 39586.9 | 13600000 | 5450000000 | 2400000000000 | 0.4919 | 0.1616 | 0.0228 | 0.0059 | 0.0752 | 0.0164 | 0.1686 | 0.0457 | 0.1595 | 0.0726 | 0.1800 | 0.1581 | 0.1458 | 0.1546 | 0.0911 | 0.1347 | 0.0752 | 0.1475 | 0.0820 | 0.2646 | 0.0015 | 0.0012 | 0.0044 | 0.0019 | 0.0059 | 0.0062 | 0.0236 | 0.0137 | 0.0707 | 0.0616 | 0.1216 | 0.1082 | 0.0892 | 0.0721 | 0.1054 | 0.0927 | 0.5777 | 0.6424 | 0.0033 | 0.0027 | 0.0044 | 0.0080 | 0.0142 | 0.0159 | 0.0381 | 0.0491 | 0.0817 | 0.1048 | 0.1569 | 0.1605 | 0.1122 | 0.1061 | 0.1100 | 0.1194 | 0.4793 | 0.4337 | 0.0009 | 0.0062 | 0.0133 | 0.0318 | 0.0681 | 0.1388 | 0.1149 | 0.1114 | 0.5146 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 804 | 192 | | 9922 | 14775 | 134.6 | 40.27 | 276.51 | 259.87 | 90 | 102 | 111 | 120 | 129 | 139 | 151 | 165 | 185 | 0.0923 | 1363 | 0.678 | 210.00 | 48.17 | 5 | 0.0555 | 551 | 0.0016 | 25.40 | 6.776 | 0.2333 | 19732.5 | 3150000 | 551000000 | 105000000000 | 0.4834 | 0.1711 | 0.0002 | 0.0002 | 0.0017 | 0.0006 | 0.0103 | 0.0011 | 0.0422 | 0.0040 | 0.1105 | 0.0312 | 0.1807 | 0.0675 | 0.1790 | 0.0732 | 0.1797 | 0.1114 | 0.2958 | 0.7108 | 0.0000 | 0.0001 | 0.0008 | 0.0005 | 0.0029 | 0.0007 | 0.0109 | 0.0020 | 0.0409 | 0.0198 | 0.0753 | 0.0371 | 0.0711 | 0.0313 | 0.0968 | 0.0504 | 0.7013 | 0.8580 | 0.0027 | 0.0123 | 0.0096 | 0.0212 | 0.0183 | 0.0368 | 0.0636 | 0.0982 | 0.1208 | 0.1618 | 0.1707 | 0.1696 | 0.1304 | 0.1027 | 0.1405 | 0.1395 | 0.3432 | 0.2578 | 0.0009 | 0.0023 | 0.0100 | 0.0275 | 0.0776 | 0.1327 | 0.1116 | 0.1316 | 0.5059 | 27 | 54 | 105 | 157 | 206 | 265 | 334 | 441 | 628 | 0.0057 | 57.11 | 6.881 | 0.3026 | 143987.0 | 105000000 | 93700000000 | 95000000000000 | 0.6013 | 0.0968 | 0.0216 | 0.0014 | 0.0960 | 0.0083 | 0.1877 | 0.0540 | 0.1629 | 0.0789 | 0.1693 | 0.1505 | 0.1733 | 0.1848 | 0.0968 | 0.1576 | 0.0464 | 0.1582 | 0.0460 | 0.2061 | 0.0006 | 0.0002 | 0.0016 | 0.0005 | 0.0059 | 0.0036 | 0.0231 | 0.0129 | 0.0764 | 0.0640 | 0.1265 | 0.1009 | 0.0993 | 0.0832 | 0.1089 | 0.1172 | 0.5577 | 0.6175 | 0.0025 | 0.0011 | 0.0056 | 0.0083 | 0.0181 | 0.0174 | 0.0350 | 0.0365 | 0.0934 | 0.0970 | 0.1313 | 0.1352 | 0.0834 | 0.0918 | 0.1084 | 0.1086 | 0.5223 | 0.5041 | 0.0012 | 0.0041 | 0.0118 | 0.0325 | 0.0905 | 0.1330 | 0.0907 | 0.1109 | 0.5253 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 811 | 224 | | 3862 | 6781 | 328.4 | 152.30 | 138.02 | 238.95 | 140 | 175 | 209 | 260 | 309 | 370 | 436 | 481 | 535 | 0.0967 | 656 | 1.166 | 181.47 | 58.73 | 2 | 0.1144 | 442 | 0.0022 | 6.00 | 6.354 | 0.3863 | 131046.0 | 59300000 | 29000000000 | 15000000000000 | 0.3371 | 0.2738 | 0.0023 | 0.0005 | 0.0000 | 0.0011 | 0.0046 | 0.0043 | 0.0230 | 0.0097 | 0.0908 | 0.0500 | 0.1517 | 0.0844 | 0.1287 | 0.0580 | 0.1356 | 0.0876 | 0.4632 | 0.7045 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0048 | 0.0007 | 0.0205 | 0.0209 | 0.0301 | 0.0301 | 0.0261 | 0.0195 | 0.0305 | 0.0280 | 0.8872 | 0.9005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0007 | 0.0052 | 0.0091 | 0.0207 | 0.0252 | 0.0342 | 0.0379 | 0.0726 | 0.0344 | 0.0654 | 0.0456 | 0.0840 | 0.8471 | 0.7168 | 0.0000 | 0.0000 | 0.0022 | 0.0039 | 0.0257 | 0.0363 | 0.0262 | 0.0312 | 0.8745 | 11 | 14 | 19 | 24 | 34 | 55 | 99 | 200 | 413 | 0.0754 | 21.49 | 4.311 | 0.6192 | 76139.6 | 68600000 | 77600000000 | 100000000000000 | 0.5118 | 0.1375 | 0.0101 | 0.0061 | 0.0553 | 0.0073 | 0.1508 | 0.0340 | 0.1508 | 0.0643 | 0.2462 | 0.1541 | 0.1683 | 0.2184 | 0.0955 | 0.1311 | 0.0628 | 0.1226 | 0.0603 | 0.2621 | 0.0000 | 0.0014 | 0.0021 | 0.0023 | 0.0057 | 0.0027 | 0.0114 | 0.0099 | 0.0532 | 0.0537 | 0.0749 | 0.0722 | 0.0583 | 0.0550 | 0.0800 | 0.0753 | 0.7145 | 0.7276 | 0.0000 | 0.0000 | 0.0039 | 0.0022 | 0.0039 | 0.0036 | 0.0123 | 0.0129 | 0.0578 | 0.0646 | 0.0884 | 0.0940 | 0.0676 | 0.0560 | 0.0799 | 0.0933 | 0.6862 | 0.6734 | 0.0006 | 0.0029 | 0.0053 | 0.0117 | 0.0516 | 0.0844 | 0.0668 | 0.0850 | 0.6917 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1174 | 846 | | 5064 | 8048 | 118.7 | 34.40 | 119.92 | 88.88 | 80 | 91 | 100 | 107 | 114 | 121 | 130 | 142 | 161 | 0.1006 | 810 | 1.202 | 110.39 | 36.80 | 1 | 0.0519 | 263 | 0.0023 | 19.24 | 6.374 | 0.2651 | 15273.8 | 2150000 | 332000000 | 57200000000 | 0.4585 | 0.1999 | 0.0000 | 0.0000 | 0.0032 | 0.0011 | 0.0165 | 0.0029 | 0.0330 | 0.0052 | 0.0979 | 0.0270 | 0.1707 | 0.0583 | 0.1528 | 0.0615 | 0.1854 | 0.1097 | 0.3404 | 0.7342 | 0.0000 | 0.0000 | 0.0008 | 0.0004 | 0.0053 | 0.0010 | 0.0127 | 0.0016 | 0.0433 | 0.0179 | 0.0763 | 0.0324 | 0.0610 | 0.0311 | 0.0971 | 0.0575 | 0.7036 | 0.8580 | 0.0060 | 0.0218 | 0.0060 | 0.0170 | 0.0320 | 0.0243 | 0.0659 | 0.0898 | 0.1229 | 0.1723 | 0.1758 | 0.2112 | 0.1269 | 0.1092 | 0.1479 | 0.1286 | 0.3167 | 0.2257 | 0.0027 | 0.0018 | 0.0121 | 0.0318 | 0.0854 | 0.1239 | 0.0962 | 0.1395 | 0.5067 | 18 | 37 | 59 | 82 | 107 | 129 | 156 | 187 | 238 | 0.0034 | 26.76 | 6.490 | 0.3055 | 22278.7 | 5270000 | 1470000000 | 464000000000 | 0.4991 | 0.1573 | 0.0146 | 0.0016 | 0.0781 | 0.0070 | 0.1684 | 0.0269 | 0.1775 | 0.0701 | 0.1891 | 0.1509 | 0.1647 | 0.1985 | 0.1031 | 0.1722 | 0.0653 | 0.1630 | 0.0390 | 0.2099 | 0.0007 | 0.0004 | 0.0032 | 0.0006 | 0.0057 | 0.0038 | 0.0214 | 0.0111 | 0.0578 | 0.0521 | 0.1026 | 0.0899 | 0.0839 | 0.0694 | 0.1046 | 0.0895 | 0.6202 | 0.6832 | 0.0022 | 0.0015 | 0.0051 | 0.0176 | 0.0138 | 0.0263 | 0.0377 | 0.0512 | 0.1048 | 0.1146 | 0.1247 | 0.1258 | 0.1215 | 0.1107 | 0.1265 | 0.1287 | 0.4637 | 0.4237 | 0.0006 | 0.0028 | 0.0104 | 0.0254 | 0.0725 | 0.1253 | 0.1041 | 0.1202 | 0.5387 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 658 | 779 | | 5169 | 11172 | 137.7 | 32.46 | 113.17 | 91.87 | 100 | 111 | 120 | 127 | 134 | 142 | 150 | 160 | 178 | 0.0719 | 803 | 0.859 | 104.81 | 28.16 | 1 | 0.0530 | 274 | 0.0021 | 21.91 | 6.455 | 0.2447 | 20003.2 | 3080000 | 502000000 | 87100000000 | 0.4380 | 0.2131 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0072 | 0.0000 | 0.0208 | 0.0021 | 0.0760 | 0.0199 | 0.1417 | 0.0475 | 0.1466 | 0.0488 | 0.1981 | 0.0785 | 0.4089 | 0.8031 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0077 | 0.0008 | 0.0363 | 0.0134 | 0.0672 | 0.0294 | 0.0593 | 0.0203 | 0.0997 | 0.0401 | 0.7272 | 0.8959 | 0.0081 | 0.0139 | 0.0185 | 0.0209 | 0.0288 | 0.0453 | 0.0819 | 0.1603 | 0.1453 | 0.1672 | 0.1926 | 0.1812 | 0.1119 | 0.0836 | 0.1407 | 0.1324 | 0.2722 | 0.1951 | 0.0025 | 0.0042 | 0.0148 | 0.0420 | 0.0954 | 0.1238 | 0.1081 | 0.1361 | 0.4731 | 15 | 30 | 49 | 70 | 92 | 118 | 149 | 185 | 238 | 0.0049 | 34.56 | 6.477 | 0.3146 | 21247.0 | 5290000 | 1630000000 | 593000000000 | 0.5230 | 0.1320 | 0.0237 | 0.0013 | 0.1084 | 0.0065 | 0.2323 | 0.0500 | 0.1730 | 0.0940 | 0.1806 | 0.1655 | 0.1412 | 0.2079 | 0.0846 | 0.1542 | 0.0415 | 0.1364 | 0.0146 | 0.1841 | 0.0004 | 0.0003 | 0.0009 | 0.0000 | 0.0057 | 0.0022 | 0.0210 | 0.0114 | 0.0670 | 0.0515 | 0.1169 | 0.0950 | 0.0867 | 0.0772 | 0.1217 | 0.1026 | 0.5799 | 0.6597 | 0.0011 | 0.0007 | 0.0029 | 0.0076 | 0.0111 | 0.0152 | 0.0315 | 0.0444 | 0.0978 | 0.1136 | 0.1574 | 0.1758 | 0.0999 | 0.1242 | 0.1479 | 0.1351 | 0.4505 | 0.3834 | 0.0009 | 0.0021 | 0.0064 | 0.0277 | 0.0813 | 0.1285 | 0.1054 | 0.1321 | 0.5156 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 224 | 158 | | 4015 | 9039 | 129.9 | 42.42 | 240.53 | 197.92 | 83 | 93 | 102 | 112 | 122 | 132 | 145 | 164 | 192 | 0.0824 | 745 | 0.608 | 137.06 | 32.56 | 2 | 0.0914 | 367 | 0.0017 | 32.79 | 6.720 | 0.2241 | 18668.6 | 2960000 | 512000000 | 95700000000 | 0.4366 | 0.2129 | 0.0006 | 0.0000 | 0.0083 | 0.0000 | 0.0286 | 0.0025 | 0.0787 | 0.0136 | 0.1398 | 0.0414 | 0.1937 | 0.0891 | 0.1717 | 0.0999 | 0.1805 | 0.1349 | 0.1981 | 0.6186 | 0.0004 | 0.0000 | 0.0029 | 0.0000 | 0.0065 | 0.0003 | 0.0199 | 0.0051 | 0.0513 | 0.0221 | 0.0863 | 0.0444 | 0.0794 | 0.0441 | 0.1054 | 0.0644 | 0.6480 | 0.8197 | 0.0042 | 0.0152 | 0.0094 | 0.0095 | 0.0147 | 0.0171 | 0.0546 | 0.0778 | 0.1322 | 0.1670 | 0.1689 | 0.2068 | 0.1186 | 0.1214 | 0.1448 | 0.1613 | 0.3526 | 0.2239 | 0.0023 | 0.0047 | 0.0088 | 0.0379 | 0.0852 | 0.1435 | 0.1144 | 0.1394 | 0.4638 | 58 | 87 | 118 | 150 | 188 | 231 | 284 | 357 | 481 | 0.0022 | 55.46 | 6.797 | 0.2505 | 97022.8 | 58800000 | 49300000000 | 53100000000000 | 0.5450 | 0.1246 | 0.0221 | 0.0008 | 0.1131 | 0.0059 | 0.2262 | 0.0326 | 0.2048 | 0.0940 | 0.1725 | 0.1716 | 0.1357 | 0.2107 | 0.0707 | 0.1674 | 0.0368 | 0.1532 | 0.0181 | 0.1637 | 0.0007 | 0.0000 | 0.0018 | 0.0009 | 0.0057 | 0.0020 | 0.0218 | 0.0142 | 0.0807 | 0.0614 | 0.1388 | 0.1041 | 0.1118 | 0.0876 | 0.1447 | 0.1228 | 0.4940 | 0.6070 | 0.0011 | 0.0025 | 0.0057 | 0.0074 | 0.0171 | 0.0319 | 0.0566 | 0.0662 | 0.1265 | 0.1363 | 0.1686 | 0.1878 | 0.1367 | 0.1099 | 0.1363 | 0.1403 | 0.3513 | 0.3178 | 0.0015 | 0.0023 | 0.0079 | 0.0347 | 0.1096 | 0.1629 | 0.1175 | 0.1597 | 0.4040 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 709 | 307 | | 13145 | 33263 | 215.6 | 52.79 | 151.28 | 220.31 | 149 | 174 | 189 | 203 | 216 | 228 | 242 | 259 | 283 | 0.0407 | 1355 | 1.265 | 23.41 | 8.25 | 1 | 0.0043 | 57 | 0.0010 | 34.06 | 7.246 | 0.2053 | 49257.3 | 11800000 | 2960000000 | 769000000000 | 0.3831 | 0.2579 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0040 | 0.0005 | 0.0168 | 0.0025 | 0.0464 | 0.0130 | 0.0932 | 0.0319 | 0.1084 | 0.0316 | 0.1447 | 0.0480 | 0.5842 | 0.8725 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0001 | 0.0053 | 0.0012 | 0.0169 | 0.0077 | 0.0331 | 0.0189 | 0.0378 | 0.0116 | 0.0514 | 0.0186 | 0.8537 | 0.9419 | 0.0054 | 0.0148 | 0.0050 | 0.0411 | 0.0204 | 0.0542 | 0.0549 | 0.1117 | 0.0976 | 0.1215 | 0.1187 | 0.1560 | 0.1145 | 0.1034 | 0.1287 | 0.1051 | 0.4549 | 0.2923 | 0.0014 | 0.0017 | 0.0065 | 0.0214 | 0.0510 | 0.0797 | 0.0892 | 0.1055 | 0.6436 | 12 | 15 | 20 | 31 | 50 | 92 | 148 | 246 | 442 | 0.0346 | 37.24 | 5.501 | 0.4820 | 71418.1 | 52500000 | 49100000000 | 54400000000000 | 0.4267 | 0.2463 | 0.0312 | 0.0012 | 0.1250 | 0.0165 | 0.2039 | 0.0728 | 0.1419 | 0.0958 | 0.1495 | 0.1578 | 0.1419 | 0.1887 | 0.0914 | 0.1192 | 0.0623 | 0.1242 | 0.0530 | 0.2238 | 0.0005 | 0.0003 | 0.0020 | 0.0009 | 0.0057 | 0.0031 | 0.0160 | 0.0110 | 0.0513 | 0.0476 | 0.0861 | 0.0794 | 0.0620 | 0.0504 | 0.0781 | 0.0712 | 0.6982 | 0.7362 | 0.0005 | 0.0004 | 0.0014 | 0.0037 | 0.0064 | 0.0063 | 0.0183 | 0.0174 | 0.0625 | 0.0699 | 0.1084 | 0.1182 | 0.0749 | 0.0836 | 0.1034 | 0.1020 | 0.6243 | 0.5984 | 0.0008 | 0.0015 | 0.0050 | 0.0158 | 0.0576 | 0.0968 | 0.0701 | 0.0894 | 0.6629 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1097 | 401 | | 5619 | 10511 | 100.4 | 25.69 | 150.94 | 167.26 | 71 | 79 | 86 | 92 | 97 | 103 | 110 | 119 | 132 | 0.0786 | 826 | 0.983 | 96.05 | 27.31 | 1 | 0.0418 | 235 | 0.0033 | 15.27 | 6.069 | 0.2967 | 10734.1 | 1230000 | 151000000 | 19900000000 | 0.4514 | 0.2026 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0093 | 0.0000 | 0.0335 | 0.0025 | 0.0924 | 0.0231 | 0.1475 | 0.0450 | 0.1673 | 0.0550 | 0.1991 | 0.0865 | 0.3487 | 0.7879 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0000 | 0.0089 | 0.0002 | 0.0392 | 0.0149 | 0.0643 | 0.0223 | 0.0770 | 0.0225 | 0.1061 | 0.0415 | 0.7020 | 0.8987 | 0.0103 | 0.0074 | 0.0197 | 0.0245 | 0.0310 | 0.0515 | 0.0874 | 0.0711 | 0.1400 | 0.1985 | 0.1805 | 0.1642 | 0.1184 | 0.1201 | 0.1391 | 0.1569 | 0.2735 | 0.2059 | 0.0012 | 0.0051 | 0.0125 | 0.0446 | 0.0896 | 0.1405 | 0.1151 | 0.1526 | 0.4387 | 11 | 17 | 32 | 53 | 79 | 117 | 181 | 290 | 415 | 0.0097 | 71.41 | 6.470 | 0.3608 | 50757.6 | 22700000 | 11700000000 | 6580000000000 | 0.5255 | 0.1681 | 0.0205 | 0.0024 | 0.1212 | 0.0122 | 0.2269 | 0.0538 | 0.1561 | 0.1204 | 0.1448 | 0.1703 | 0.1458 | 0.1689 | 0.0791 | 0.1385 | 0.0565 | 0.1434 | 0.0493 | 0.1899 | 0.0005 | 0.0004 | 0.0015 | 0.0008 | 0.0056 | 0.0018 | 0.0121 | 0.0135 | 0.0522 | 0.0488 | 0.0869 | 0.0725 | 0.0689 | 0.0674 | 0.0959 | 0.0926 | 0.6765 | 0.7021 | 0.0000 | 0.0007 | 0.0022 | 0.0011 | 0.0060 | 0.0049 | 0.0133 | 0.0226 | 0.0616 | 0.0560 | 0.1042 | 0.1173 | 0.0801 | 0.0920 | 0.1087 | 0.1117 | 0.6238 | 0.5937 | 0.0014 | 0.0025 | 0.0061 | 0.0150 | 0.0574 | 0.0872 | 0.0738 | 0.0955 | 0.6611 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1049 | 270 | | 3875 | 7952 | 133.1 | 35.91 | 157.83 | 125.74 | 94 | 104 | 113 | 121 | 128 | 136 | 145 | 157 | 179 | 0.0832 | 662 | 0.854 | 78.82 | 25.55 | 2 | 0.0565 | 219 | 0.0020 | 26.25 | 6.494 | 0.2455 | 18997.6 | 2930000 | 490000000 | 89600000000 | 0.4209 | 0.2213 | 0.0000 | 0.0003 | 0.0004 | 0.0000 | 0.0074 | 0.0003 | 0.0302 | 0.0020 | 0.0944 | 0.0294 | 0.1627 | 0.0582 | 0.1605 | 0.0616 | 0.1828 | 0.0913 | 0.3616 | 0.7570 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0003 | 0.0462 | 0.0196 | 0.0716 | 0.0346 | 0.0726 | 0.0291 | 0.1044 | 0.0471 | 0.6921 | 0.8694 | 0.0086 | 0.0097 | 0.0143 | 0.0065 | 0.0399 | 0.0259 | 0.0799 | 0.1003 | 0.1241 | 0.1586 | 0.1526 | 0.1715 | 0.0984 | 0.1100 | 0.1184 | 0.1683 | 0.3638 | 0.2492 | 0.0024 | 0.0083 | 0.0166 | 0.0391 | 0.1073 | 0.1375 | 0.1203 | 0.1316 | 0.4369 | 26 | 44 | 68 | 98 | 128 | 163 | 203 | 251 | 336 | 0.0035 | 41.32 | 6.588 | 0.3220 | 40720.6 | 13800000 | 5550000000 | 2540000000000 | 0.4558 | 0.2138 | 0.0196 | 0.0022 | 0.0713 | 0.0072 | 0.1578 | 0.0421 | 0.1767 | 0.0623 | 0.2000 | 0.1326 | 0.1804 | 0.1870 | 0.1084 | 0.1581 | 0.0531 | 0.1675 | 0.0327 | 0.2410 | 0.0012 | 0.0000 | 0.0015 | 0.0021 | 0.0055 | 0.0037 | 0.0159 | 0.0118 | 0.0585 | 0.0468 | 0.0938 | 0.0773 | 0.0774 | 0.0664 | 0.1074 | 0.0880 | 0.6388 | 0.7040 | 0.0008 | 0.0034 | 0.0053 | 0.0087 | 0.0120 | 0.0135 | 0.0361 | 0.0429 | 0.0847 | 0.1118 | 0.1295 | 0.1301 | 0.1043 | 0.1186 | 0.1401 | 0.1533 | 0.4872 | 0.4178 | 0.0006 | 0.0033 | 0.0108 | 0.0222 | 0.0752 | 0.1049 | 0.0869 | 0.1254 | 0.5707 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 933 | 214 | | 5101 | 5870 | 110.2 | 27.49 | 259.56 | 186.24 | 81 | 88 | 94 | 100 | 106 | 112 | 119 | 129 | 146 | 0.1181 | 693 | 0.954 | 104.01 | 27.86 | 1 | 0.0514 | 262 | 0.0033 | 15.83 | 6.117 | 0.2885 | 12892.3 | 1610000 | 215000000 | 30600000000 | 0.4365 | 0.2174 | 0.0000 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0002 | 0.0327 | 0.0041 | 0.0791 | 0.0237 | 0.1405 | 0.0507 | 0.1464 | 0.0487 | 0.1803 | 0.0643 | 0.4074 | 0.8083 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0027 | 0.0000 | 0.0133 | 0.0010 | 0.0360 | 0.0143 | 0.0691 | 0.0261 | 0.0718 | 0.0191 | 0.1049 | 0.0323 | 0.7006 | 0.9072 | 0.0043 | 0.0000 | 0.0076 | 0.0104 | 0.0205 | 0.0286 | 0.0777 | 0.1042 | 0.1295 | 0.1823 | 0.1672 | 0.2031 | 0.1176 | 0.0964 | 0.1316 | 0.1406 | 0.3441 | 0.2344 | 0.0009 | 0.0045 | 0.0190 | 0.0407 | 0.0945 | 0.1392 | 0.1062 | 0.1456 | 0.4494 | 32 | 73 | 127 | 182 | 237 | 290 | 350 | 422 | 519 | 0.0019 | 77.87 | 7.288 | 0.2207 | 102053.0 | 48600000 | 26200000000 | 15400000000000 | 0.5763 | 0.1260 | 0.0142 | 0.0028 | 0.0809 | 0.0120 | 0.1813 | 0.0384 | 0.2018 | 0.0791 | 0.1947 | 0.1512 | 0.1493 | 0.1883 | 0.1084 | 0.1684 | 0.0516 | 0.1489 | 0.0178 | 0.2109 | 0.0003 | 0.0003 | 0.0018 | 0.0013 | 0.0055 | 0.0029 | 0.0160 | 0.0108 | 0.0674 | 0.0567 | 0.1167 | 0.0966 | 0.0890 | 0.0764 | 0.1290 | 0.1066 | 0.5743 | 0.6484 | 0.0014 | 0.0036 | 0.0019 | 0.0006 | 0.0113 | 0.0164 | 0.0386 | 0.0498 | 0.1050 | 0.1343 | 0.1671 | 0.1926 | 0.1266 | 0.1179 | 0.1558 | 0.1422 | 0.3922 | 0.3426 | 0.0000 | 0.0033 | 0.0052 | 0.0298 | 0.0818 | 0.1369 | 0.1153 | 0.1447 | 0.4829 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 976 | 862 | | 8371 | 10040 | 119.6 | 44.92 | 155.74 | 155.70 | 66 | 82 | 94 | 104 | 115 | 126 | 139 | 155 | 180 | 0.1011 | 1015 | 0.966 | 89.94 | 27.51 | 4 | 0.0288 | 241 | 0.0007 | 62.88 | 7.556 | 0.1767 | 16326.4 | 2490000 | 417000000 | 75800000000 | 0.4543 | 0.2049 | 0.0006 | 0.0000 | 0.0058 | 0.0003 | 0.0252 | 0.0021 | 0.0659 | 0.0106 | 0.1494 | 0.0457 | 0.1923 | 0.0930 | 0.1593 | 0.0951 | 0.1636 | 0.1235 | 0.2379 | 0.6298 | 0.0002 | 0.0000 | 0.0010 | 0.0001 | 0.0033 | 0.0005 | 0.0121 | 0.0036 | 0.0500 | 0.0240 | 0.0668 | 0.0448 | 0.0596 | 0.0367 | 0.0870 | 0.0539 | 0.7200 | 0.8364 | 0.0009 | 0.0034 | 0.0035 | 0.0017 | 0.0132 | 0.0299 | 0.0475 | 0.0708 | 0.1174 | 0.1561 | 0.1500 | 0.1698 | 0.1047 | 0.0998 | 0.1341 | 0.1519 | 0.4288 | 0.3166 | 0.0011 | 0.0037 | 0.0045 | 0.0250 | 0.0677 | 0.1195 | 0.0937 | 0.1219 | 0.5629 | 15 | 25 | 47 | 74 | 107 | 150 | 200 | 260 | 359 | 0.0159 | 26.97 | 5.856 | 0.3967 | 48494.1 | 21800000 | 12600000000 | 8830000000000 | 0.5977 | 0.0835 | 0.0353 | 0.0018 | 0.1603 | 0.0185 | 0.3052 | 0.0912 | 0.1733 | 0.1119 | 0.1411 | 0.1866 | 0.1005 | 0.2165 | 0.0460 | 0.1263 | 0.0314 | 0.1278 | 0.0069 | 0.1193 | 0.0002 | 0.0006 | 0.0011 | 0.0009 | 0.0055 | 0.0039 | 0.0196 | 0.0131 | 0.0627 | 0.0586 | 0.1262 | 0.1037 | 0.0878 | 0.0736 | 0.1216 | 0.1085 | 0.5754 | 0.6371 | 0.0006 | 0.0030 | 0.0043 | 0.0059 | 0.0101 | 0.0111 | 0.0336 | 0.0392 | 0.0864 | 0.1103 | 0.1639 | 0.1799 | 0.1184 | 0.1136 | 0.1334 | 0.1358 | 0.4495 | 0.4012 | 0.0008 | 0.0015 | 0.0069 | 0.0240 | 0.0769 | 0.1428 | 0.0979 | 0.1329 | 0.5164 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 155 | | 5618 | 13253 | 344.2 | 70.32 | 104.68 | 99.98 | 259 | 282 | 300 | 316 | 333 | 354 | 379 | 407 | 444 | 0.0684 | 907 | 0.910 | 83.20 | 23.02 | 1 | 0.0377 | 212 | 0.0019 | 20.54 | 6.561 | 0.2353 | 123384.0 | 46000000 | 17900000000 | 7180000000000 | 0.3957 | 0.2470 | 0.0003 | 0.0000 | 0.0008 | 0.0002 | 0.0063 | 0.0002 | 0.0181 | 0.0011 | 0.0550 | 0.0161 | 0.1125 | 0.0345 | 0.1341 | 0.0319 | 0.1675 | 0.0521 | 0.5055 | 0.8638 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0032 | 0.0000 | 0.0071 | 0.0002 | 0.0199 | 0.0120 | 0.0402 | 0.0218 | 0.0557 | 0.0130 | 0.0771 | 0.0230 | 0.7960 | 0.9301 | 0.0029 | 0.0140 | 0.0069 | 0.0421 | 0.0255 | 0.0514 | 0.0609 | 0.1495 | 0.1159 | 0.1822 | 0.1906 | 0.1869 | 0.1375 | 0.1122 | 0.1503 | 0.1075 | 0.3094 | 0.1542 | 0.0020 | 0.0024 | 0.0071 | 0.0256 | 0.0643 | 0.1057 | 0.0923 | 0.1179 | 0.5826 | 14 | 27 | 43 | 59 | 75 | 94 | 119 | 159 | 237 | 0.0186 | 8.63 | 5.042 | 0.5074 | 20954.6 | 6170000 | 2290000000 | 982000000000 | 0.4377 | 0.2064 | 0.0105 | 0.0017 | 0.0659 | 0.0063 | 0.1467 | 0.0244 | 0.1714 | 0.0701 | 0.1841 | 0.1287 | 0.1586 | 0.1670 | 0.1270 | 0.1575 | 0.0857 | 0.1608 | 0.0501 | 0.2834 | 0.0010 | 0.0010 | 0.0042 | 0.0013 | 0.0055 | 0.0034 | 0.0205 | 0.0174 | 0.0627 | 0.0477 | 0.0920 | 0.0753 | 0.0818 | 0.0727 | 0.1040 | 0.0953 | 0.6284 | 0.6859 | 0.0011 | 0.0027 | 0.0038 | 0.0036 | 0.0089 | 0.0103 | 0.0277 | 0.0262 | 0.0728 | 0.0839 | 0.1098 | 0.1194 | 0.0899 | 0.0902 | 0.1106 | 0.1154 | 0.5756 | 0.5484 | 0.0011 | 0.0045 | 0.0087 | 0.0268 | 0.0665 | 0.1035 | 0.0854 | 0.1079 | 0.5957 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 426 | 374 | | 4318 | 14420 | 143.7 | 34.49 | 119.50 | 125.97 | 103 | 114 | 123 | 131 | 140 | 148 | 158 | 170 | 188 | 0.0620 | 894 | 1.020 | 115.11 | 27.29 | 1 | 0.0602 | 260 | 0.0019 | 27.37 | 6.560 | 0.2321 | 21832.7 | 3510000 | 599000000 | 108000000000 | 0.4264 | 0.2220 | 0.0004 | 0.0000 | 0.0035 | 0.0005 | 0.0196 | 0.0012 | 0.0369 | 0.0027 | 0.0914 | 0.0222 | 0.1656 | 0.0530 | 0.1672 | 0.0527 | 0.1770 | 0.0782 | 0.3383 | 0.7894 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0000 | 0.0113 | 0.0014 | 0.0416 | 0.0148 | 0.0794 | 0.0319 | 0.0708 | 0.0195 | 0.1002 | 0.0380 | 0.6908 | 0.8945 | 0.0049 | 0.0114 | 0.0160 | 0.0114 | 0.0294 | 0.0456 | 0.0896 | 0.1787 | 0.1521 | 0.2129 | 0.1816 | 0.2053 | 0.1411 | 0.0913 | 0.1546 | 0.1293 | 0.2307 | 0.1141 | 0.0005 | 0.0031 | 0.0112 | 0.0386 | 0.0910 | 0.1352 | 0.1256 | 0.1546 | 0.4403 | 17 | 24 | 35 | 47 | 65 | 91 | 142 | 211 | 313 | 0.0080 | 38.15 | 6.234 | 0.3884 | 30147.3 | 10600000 | 4400000000 | 2040000000000 | 0.5107 | 0.1394 | 0.0427 | 0.0034 | 0.1280 | 0.0141 | 0.2110 | 0.0584 | 0.1420 | 0.1202 | 0.1528 | 0.1742 | 0.1412 | 0.1803 | 0.1009 | 0.1302 | 0.0559 | 0.1289 | 0.0256 | 0.1903 | 0.0007 | 0.0013 | 0.0025 | 0.0025 | 0.0054 | 0.0058 | 0.0116 | 0.0120 | 0.0497 | 0.0465 | 0.0797 | 0.0690 | 0.0606 | 0.0582 | 0.0869 | 0.0833 | 0.7029 | 0.7214 | 0.0002 | 0.0008 | 0.0009 | 0.0008 | 0.0044 | 0.0074 | 0.0114 | 0.0183 | 0.0634 | 0.0731 | 0.0992 | 0.1123 | 0.0727 | 0.0847 | 0.1113 | 0.1107 | 0.6365 | 0.5920 | 0.0004 | 0.0021 | 0.0035 | 0.0136 | 0.0496 | 0.0910 | 0.0683 | 0.0899 | 0.6816 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 140 | | 4015 | 11442 | 298.5 | 93.89 | 283.49 | 327.91 | 188 | 224 | 248 | 270 | 290 | 313 | 337 | 371 | 423 | 0.0718 | 821 | 0.641 | 110.89 | 16.16 | 3 | 0.0590 | 237 | 0.0005 | 119.77 | 7.721 | 0.1137 | 97912.3 | 34900000 | 13400000000 | 5490000000000 | 0.4228 | 0.1994 | 0.0000 | 0.0000 | 0.0005 | 0.0003 | 0.0078 | 0.0000 | 0.0352 | 0.0049 | 0.0906 | 0.0391 | 0.1684 | 0.0564 | 0.1361 | 0.0524 | 0.1522 | 0.0795 | 0.4092 | 0.7675 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0135 | 0.0016 | 0.0347 | 0.0237 | 0.0663 | 0.0307 | 0.0579 | 0.0234 | 0.0710 | 0.0373 | 0.7547 | 0.8833 | 0.0011 | 0.0093 | 0.0032 | 0.0023 | 0.0086 | 0.0163 | 0.0452 | 0.0629 | 0.0893 | 0.0979 | 0.1453 | 0.1375 | 0.0969 | 0.1235 | 0.1163 | 0.1142 | 0.4941 | 0.4359 | 0.0005 | 0.0005 | 0.0032 | 0.0244 | 0.0684 | 0.1087 | 0.0976 | 0.1124 | 0.5843 | 18 | 23 | 31 | 69 | 150 | 246 | 370 | 532 | 762 | 0.0260 | 64.88 | 6.232 | 0.4074 | 187886.0 | 166000000 | 173000000000 | 201000000000000 | 0.6183 | 0.1150 | 0.0315 | 0.0018 | 0.0954 | 0.0093 | 0.2028 | 0.0466 | 0.1778 | 0.0888 | 0.1759 | 0.1607 | 0.1389 | 0.1793 | 0.0880 | 0.1474 | 0.0528 | 0.1482 | 0.0370 | 0.2179 | 0.0008 | 0.0000 | 0.0015 | 0.0004 | 0.0054 | 0.0022 | 0.0149 | 0.0104 | 0.0492 | 0.0440 | 0.0677 | 0.0593 | 0.0620 | 0.0557 | 0.0989 | 0.0825 | 0.6996 | 0.7454 | 0.0014 | 0.0000 | 0.0038 | 0.0019 | 0.0049 | 0.0074 | 0.0181 | 0.0211 | 0.0585 | 0.0692 | 0.0937 | 0.0977 | 0.0766 | 0.0922 | 0.1110 | 0.1151 | 0.6320 | 0.5954 | 0.0005 | 0.0026 | 0.0062 | 0.0133 | 0.0554 | 0.0778 | 0.0700 | 0.1011 | 0.6730 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1022 | 692 | | 3454 | 3530 | 167.4 | 41.65 | 180.50 | 117.23 | 122 | 134 | 143 | 152 | 160 | 170 | 182 | 197 | 221 | 0.1552 | 548 | 0.994 | 92.70 | 30.02 | 1 | 0.0753 | 260 | 0.0018 | 25.32 | 6.610 | 0.2337 | 29750.6 | 5640000 | 1140000000 | 247000000000 | 0.4167 | 0.2267 | 0.0019 | 0.0000 | 0.0014 | 0.0000 | 0.0079 | 0.0019 | 0.0200 | 0.0045 | 0.0723 | 0.0243 | 0.1361 | 0.0530 | 0.1441 | 0.0501 | 0.1716 | 0.0728 | 0.4448 | 0.7935 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0033 | 0.0000 | 0.0094 | 0.0012 | 0.0333 | 0.0171 | 0.0716 | 0.0339 | 0.0651 | 0.0233 | 0.0763 | 0.0369 | 0.7401 | 0.8876 | 0.0048 | 0.0078 | 0.0032 | 0.0078 | 0.0193 | 0.0273 | 0.0612 | 0.0898 | 0.1433 | 0.1406 | 0.1578 | 0.2031 | 0.1111 | 0.0898 | 0.1481 | 0.1680 | 0.3510 | 0.2656 | 0.0027 | 0.0040 | 0.0121 | 0.0336 | 0.0666 | 0.1217 | 0.0941 | 0.1163 | 0.5488 | 51 | 75 | 99 | 126 | 155 | 189 | 229 | 282 | 342 | 0.0019 | 49.51 | 6.719 | 0.2474 | 46319.3 | 14800000 | 5500000000 | 2270000000000 | 0.4820 | 0.1669 | 0.0110 | 0.0014 | 0.0992 | 0.0081 | 0.1983 | 0.0359 | 0.1832 | 0.0670 | 0.1749 | 0.1475 | 0.1405 | 0.2023 | 0.0992 | 0.1387 | 0.0702 | 0.1732 | 0.0234 | 0.2260 | 0.0011 | 0.0004 | 0.0032 | 0.0013 | 0.0053 | 0.0038 | 0.0185 | 0.0162 | 0.0678 | 0.0489 | 0.1070 | 0.0919 | 0.0970 | 0.0655 | 0.1436 | 0.1123 | 0.5564 | 0.6597 | 0.0017 | 0.0000 | 0.0078 | 0.0103 | 0.0138 | 0.0126 | 0.0491 | 0.0515 | 0.0956 | 0.1214 | 0.1731 | 0.1901 | 0.1051 | 0.1420 | 0.1447 | 0.1741 | 0.4091 | 0.2978 | 0.0013 | 0.0040 | 0.0047 | 0.0330 | 0.0982 | 0.1365 | 0.1063 | 0.1466 | 0.4694 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 352 | 145 | | 6842 | 23190 | 516.1 | 88.93 | 82.73 | 76.82 | 394 | 442 | 473 | 497 | 519 | 540 | 560 | 588 | 626 | 0.0471 | 1092 | 1.217 | 112.40 | 44.05 | 1 | 0.0417 | 285 | 0.0008 | 51.79 | 7.367 | 0.1654 | 274282.0 | 150000000 | 83800000000 | 48000000000000 | 0.4133 | 0.2357 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0068 | 0.0009 | 0.0395 | 0.0128 | 0.0867 | 0.0244 | 0.0880 | 0.0204 | 0.1257 | 0.0318 | 0.6515 | 0.9098 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0001 | 0.0219 | 0.0112 | 0.0469 | 0.0212 | 0.0429 | 0.0121 | 0.0560 | 0.0240 | 0.8305 | 0.9315 | 0.0064 | 0.0000 | 0.0244 | 0.0385 | 0.0450 | 0.1538 | 0.0720 | 0.1795 | 0.1362 | 0.1538 | 0.1542 | 0.1923 | 0.1105 | 0.1538 | 0.1041 | 0.0769 | 0.3470 | 0.0513 | 0.0006 | 0.0014 | 0.0071 | 0.0246 | 0.0801 | 0.1194 | 0.1251 | 0.1398 | 0.5020 | 13 | 21 | 33 | 47 | 63 | 80 | 100 | 127 | 174 | 0.0136 | 7.65 | 5.221 | 0.4945 | 12746.0 | 3030000 | 998000000 | 416000000000 | 0.4776 | 0.1511 | 0.0127 | 0.0009 | 0.0661 | 0.0029 | 0.1634 | 0.0253 | 0.1896 | 0.0621 | 0.2119 | 0.1354 | 0.1531 | 0.1850 | 0.1031 | 0.1644 | 0.0654 | 0.1703 | 0.0348 | 0.2537 | 0.0006 | 0.0001 | 0.0017 | 0.0006 | 0.0053 | 0.0027 | 0.0178 | 0.0129 | 0.0589 | 0.0423 | 0.0902 | 0.0637 | 0.0775 | 0.0651 | 0.1124 | 0.0898 | 0.6356 | 0.7229 | 0.0024 | 0.0026 | 0.0024 | 0.0051 | 0.0088 | 0.0130 | 0.0336 | 0.0403 | 0.0825 | 0.0987 | 0.1329 | 0.1479 | 0.1037 | 0.1076 | 0.1323 | 0.1377 | 0.5013 | 0.4472 | 0.0009 | 0.0038 | 0.0065 | 0.0246 | 0.0676 | 0.1127 | 0.0949 | 0.1192 | 0.5699 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1121 | 451 | | 6463 | 8308 | 92.4 | 21.14 | 64.20 | 58.22 | 68 | 75 | 80 | 85 | 90 | 96 | 102 | 109 | 121 | 0.1133 | 941 | 0.502 | 162.61 | 33.73 | 3 | 0.0791 | 511 | 0.0045 | 8.67 | 5.719 | 0.3500 | 8980.8 | 917146 | 98200000 | 11000000000 | 0.4709 | 0.1844 | 0.0005 | 0.0000 | 0.0056 | 0.0000 | 0.0071 | 0.0007 | 0.0282 | 0.0044 | 0.0803 | 0.0230 | 0.1265 | 0.0487 | 0.1496 | 0.0470 | 0.1916 | 0.0838 | 0.4105 | 0.7925 | 0.0004 | 0.0000 | 0.0034 | 0.0000 | 0.0032 | 0.0003 | 0.0129 | 0.0024 | 0.0336 | 0.0144 | 0.0546 | 0.0290 | 0.0643 | 0.0214 | 0.0936 | 0.0415 | 0.7341 | 0.8910 | 0.0041 | 0.0140 | 0.0156 | 0.0420 | 0.0303 | 0.0812 | 0.0705 | 0.0980 | 0.1115 | 0.1765 | 0.1566 | 0.2185 | 0.1393 | 0.1176 | 0.1377 | 0.1289 | 0.3344 | 0.1232 | 0.0042 | 0.0088 | 0.0152 | 0.0412 | 0.0629 | 0.0960 | 0.0973 | 0.1255 | 0.5490 | 12 | 17 | 24 | 31 | 41 | 58 | 79 | 110 | 150 | 0.0333 | 4.43 | 4.417 | 0.5777 | 7511.6 | 1200000 | 227000000 | 48400000000 | 0.5963 | 0.1028 | 0.0286 | 0.0119 | 0.1026 | 0.0162 | 0.1765 | 0.0476 | 0.1913 | 0.1232 | 0.1647 | 0.1645 | 0.1479 | 0.1992 | 0.1016 | 0.1403 | 0.0572 | 0.1417 | 0.0296 | 0.1555 | 0.0025 | 0.0049 | 0.0042 | 0.0042 | 0.0053 | 0.0084 | 0.0181 | 0.0298 | 0.0577 | 0.0498 | 0.0936 | 0.0780 | 0.0747 | 0.0703 | 0.1234 | 0.1059 | 0.6206 | 0.6487 | 0.0019 | 0.0023 | 0.0058 | 0.0027 | 0.0089 | 0.0119 | 0.0314 | 0.0337 | 0.0823 | 0.0958 | 0.1366 | 0.1500 | 0.1029 | 0.1031 | 0.1300 | 0.1404 | 0.5000 | 0.4601 | 0.0019 | 0.0010 | 0.0088 | 0.0237 | 0.0703 | 0.1144 | 0.0930 | 0.1433 | 0.5436 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 758 | 118 | | 3722 | 7678 | 368.8 | 182.51 | 164.24 | 272.94 | 145 | 178 | 217 | 266 | 351 | 446 | 510 | 563 | 614 | 0.0847 | 650 | 1.108 | 87.24 | 31.58 | 2 | 0.0623 | 232 | 0.0018 | 10.54 | 6.623 | 0.3115 | 169332.0 | 88000000 | 48900000000 | 28300000000000 | 0.2899 | 0.3386 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0086 | 0.0047 | 0.0310 | 0.0167 | 0.1480 | 0.0670 | 0.2220 | 0.0965 | 0.1463 | 0.0810 | 0.1911 | 0.1186 | 0.2530 | 0.6122 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0010 | 0.0020 | 0.0029 | 0.0035 | 0.0201 | 0.0203 | 0.0315 | 0.0250 | 0.0220 | 0.0238 | 0.0382 | 0.0355 | 0.8844 | 0.8892 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0066 | 0.0149 | 0.0238 | 0.0411 | 0.0416 | 0.0747 | 0.0350 | 0.0691 | 0.0430 | 0.0756 | 0.8500 | 0.7208 | 0.0000 | 0.0000 | 0.0006 | 0.0017 | 0.0251 | 0.0345 | 0.0239 | 0.0395 | 0.8747 | 12 | 17 | 22 | 28 | 43 | 72 | 114 | 240 | 499 | 0.0621 | 27.12 | 4.594 | 0.6002 | 101458.0 | 93500000 | 101000000000 | 118000000000000 | 0.3873 | 0.2579 | 0.0278 | 0.0021 | 0.0732 | 0.0103 | 0.1995 | 0.0372 | 0.1692 | 0.0702 | 0.1843 | 0.1569 | 0.1162 | 0.1610 | 0.0909 | 0.1352 | 0.0707 | 0.1197 | 0.0682 | 0.3075 | 0.0019 | 0.0000 | 0.0014 | 0.0028 | 0.0053 | 0.0035 | 0.0101 | 0.0102 | 0.0483 | 0.0501 | 0.0718 | 0.0654 | 0.0565 | 0.0556 | 0.0775 | 0.0832 | 0.7271 | 0.7292 | 0.0000 | 0.0006 | 0.0041 | 0.0006 | 0.0053 | 0.0026 | 0.0077 | 0.0057 | 0.0543 | 0.0529 | 0.0721 | 0.0861 | 0.0543 | 0.0529 | 0.0874 | 0.0848 | 0.7147 | 0.7136 | 0.0005 | 0.0027 | 0.0086 | 0.0065 | 0.0507 | 0.0706 | 0.0507 | 0.0841 | 0.7256 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 789 | 385 | | 5318 | 5252 | 117.1 | 28.29 | 183.50 | 149.81 | 88 | 95 | 101 | 106 | 111 | 118 | 126 | 135 | 153 | 0.1359 | 714 | 1.185 | 99.25 | 31.11 | 1 | 0.0440 | 234 | 0.0038 | 12.98 | 5.962 | 0.3134 | 14501.7 | 1920000 | 277000000 | 44100000000 | 0.4157 | 0.2302 | 0.0009 | 0.0000 | 0.0020 | 0.0000 | 0.0054 | 0.0000 | 0.0148 | 0.0014 | 0.0594 | 0.0200 | 0.1213 | 0.0451 | 0.1410 | 0.0401 | 0.1627 | 0.0615 | 0.4926 | 0.8319 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0000 | 0.0092 | 0.0002 | 0.0304 | 0.0127 | 0.0533 | 0.0251 | 0.0612 | 0.0134 | 0.0839 | 0.0215 | 0.7570 | 0.9271 | 0.0036 | 0.0085 | 0.0107 | 0.0142 | 0.0130 | 0.0342 | 0.0627 | 0.0883 | 0.1456 | 0.2023 | 0.1692 | 0.1766 | 0.0994 | 0.0855 | 0.1669 | 0.1595 | 0.3290 | 0.2308 | 0.0013 | 0.0072 | 0.0103 | 0.0354 | 0.0752 | 0.1150 | 0.1115 | 0.1352 | 0.5090 | 34 | 56 | 79 | 108 | 140 | 180 | 233 | 298 | 398 | 0.0028 | 51.84 | 6.696 | 0.3006 | 56111.0 | 22900000 | 11200000000 | 6260000000000 | 0.5751 | 0.1077 | 0.0275 | 0.0017 | 0.1066 | 0.0098 | 0.2575 | 0.0574 | 0.1760 | 0.1074 | 0.1701 | 0.1895 | 0.1401 | 0.1959 | 0.0671 | 0.1430 | 0.0299 | 0.1310 | 0.0251 | 0.1643 | 0.0008 | 0.0000 | 0.0024 | 0.0010 | 0.0052 | 0.0029 | 0.0226 | 0.0226 | 0.0755 | 0.0634 | 0.1156 | 0.0976 | 0.0898 | 0.0789 | 0.1017 | 0.0957 | 0.5866 | 0.6379 | 0.0012 | 0.0007 | 0.0024 | 0.0052 | 0.0125 | 0.0163 | 0.0458 | 0.0570 | 0.0903 | 0.1117 | 0.1729 | 0.1805 | 0.1028 | 0.1139 | 0.1147 | 0.1220 | 0.4575 | 0.3928 | 0.0005 | 0.0044 | 0.0068 | 0.0311 | 0.0856 | 0.1465 | 0.0934 | 0.1226 | 0.5090 |