High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1215 | 337 | | 5299 | 15208 | 314.6 | 49.18 | 289.78 | 445.68 | 258 | 273 | 285 | 295 | 306 | 318 | 334 | 356 | 383 | 0.0592 | 900 | 0.916 | 116.83 | 42.76 | 1 | 0.0670 | 355 | 0.0017 | 23.16 | 6.655 | 0.2317 | 101403.0 | 33500000 | 11400000000 | 3950000000000 | 0.3986 | 0.2511 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0000 | 0.0093 | 0.0002 | 0.0305 | 0.0140 | 0.0753 | 0.0305 | 0.0827 | 0.0190 | 0.1286 | 0.0295 | 0.6705 | 0.9068 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0000 | 0.0158 | 0.0117 | 0.0404 | 0.0247 | 0.0404 | 0.0102 | 0.0640 | 0.0160 | 0.8348 | 0.9373 | 0.0063 | 0.0000 | 0.0158 | 0.0000 | 0.0412 | 0.0000 | 0.0824 | 0.0000 | 0.1173 | 0.0000 | 0.1347 | 0.0000 | 0.1094 | 0.0000 | 0.1410 | 0.0000 | 0.3518 | 0.0000 | 0.0022 | 0.0083 | 0.0188 | 0.0419 | 0.0777 | 0.1104 | 0.0877 | 0.1144 | 0.5386 | 14 | 17 | 20 | 24 | 37 | 96 | 310 | 568 | 955 | 0.0512 | 92.27 | 5.412 | 0.4889 | 282587.0 | 374000000 | 589000000000 | 1.04E+15 | 0.4260 | 0.2078 | 0.0678 | 0.0021 | 0.2554 | 0.0310 | 0.2713 | 0.1590 | 0.1515 | 0.1654 | 0.1154 | 0.1977 | 0.0736 | 0.1668 | 0.0375 | 0.0880 | 0.0202 | 0.0992 | 0.0072 | 0.0908 | 0.0000 | 0.0000 | 0.0002 | 0.0006 | 0.0006 | 0.0002 | 0.0058 | 0.0039 | 0.0392 | 0.0362 | 0.0676 | 0.0614 | 0.0464 | 0.0369 | 0.0642 | 0.0614 | 0.7760 | 0.7994 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0016 | 0.0038 | 0.0107 | 0.0111 | 0.0513 | 0.0494 | 0.0801 | 0.0970 | 0.0632 | 0.0688 | 0.0880 | 0.0932 | 0.7051 | 0.6762 | 0.0000 | 0.0000 | 0.0009 | 0.0068 | 0.0458 | 0.0717 | 0.0503 | 0.0824 | 0.7421 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 422 | 387 | | 8367 | 21686 | 338.6 | 51.23 | 216.62 | 253.93 | 275 | 292 | 307 | 321 | 337 | 351 | 367 | 383 | 406 | 0.0592 | 1284 | 1.224 | 118.07 | 44.69 | 1 | 0.0354 | 296 | 0.0016 | 21.25 | 6.715 | 0.2518 | 117279.0 | 41500000 | 15000000000 | 5540000000000 | 0.4429 | 0.2078 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0080 | 0.0001 | 0.0305 | 0.0112 | 0.0543 | 0.0192 | 0.0664 | 0.0146 | 0.1150 | 0.0208 | 0.7238 | 0.9341 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0034 | 0.0000 | 0.0155 | 0.0105 | 0.0264 | 0.0169 | 0.0305 | 0.0096 | 0.0535 | 0.0147 | 0.8698 | 0.9484 | 0.0147 | 0.0000 | 0.0209 | 0.0000 | 0.0466 | 0.0000 | 0.0798 | 0.0000 | 0.1325 | 0.0000 | 0.1509 | 0.0000 | 0.1166 | 0.0000 | 0.1387 | 0.0000 | 0.2994 | 0.0000 | 0.0029 | 0.0037 | 0.0079 | 0.0179 | 0.0489 | 0.0872 | 0.0769 | 0.1138 | 0.6407 | 23 | 31 | 44 | 65 | 97 | 158 | 256 | 389 | 599 | 0.0168 | 30.30 | 6.006 | 0.4494 | 111401.0 | 80200000 | 68700000000 | 66100000000000 | 0.5043 | 0.1472 | 0.0237 | 0.0026 | 0.1369 | 0.0072 | 0.2565 | 0.0574 | 0.1751 | 0.1186 | 0.1568 | 0.1945 | 0.1196 | 0.2092 | 0.0501 | 0.1261 | 0.0356 | 0.1132 | 0.0458 | 0.1711 | 0.0002 | 0.0003 | 0.0005 | 0.0006 | 0.0022 | 0.0014 | 0.0105 | 0.0091 | 0.0514 | 0.0447 | 0.0911 | 0.0790 | 0.0565 | 0.0498 | 0.0825 | 0.0754 | 0.7050 | 0.7396 | 0.0003 | 0.0002 | 0.0011 | 0.0016 | 0.0023 | 0.0053 | 0.0156 | 0.0192 | 0.0627 | 0.0685 | 0.1061 | 0.1174 | 0.0749 | 0.0819 | 0.0955 | 0.0997 | 0.6414 | 0.6062 | 0.0001 | 0.0003 | 0.0026 | 0.0142 | 0.0598 | 0.0932 | 0.0668 | 0.0874 | 0.6756 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 713 | 522 | | 16894 | 27359 | 277.6 | 52.05 | 216.35 | 215.57 | 208 | 237 | 256 | 269 | 281 | 294 | 306 | 320 | 341 | 0.0538 | 1471 | 1.091 | 103.16 | 31.06 | 2 | 0.0146 | 247 | 0.0019 | 13.94 | 6.613 | 0.2949 | 79797.3 | 23600000 | 7150000000 | 2220000000000 | 0.4393 | 0.2062 | 0.0005 | 0.0001 | 0.0011 | 0.0000 | 0.0033 | 0.0002 | 0.0092 | 0.0012 | 0.0381 | 0.0103 | 0.0669 | 0.0200 | 0.0670 | 0.0172 | 0.0957 | 0.0278 | 0.7182 | 0.9233 | 0.0001 | 0.0001 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0036 | 0.0009 | 0.0175 | 0.0093 | 0.0294 | 0.0173 | 0.0273 | 0.0120 | 0.0360 | 0.0204 | 0.8849 | 0.9400 | 0.0059 | 0.0000 | 0.0174 | 0.0000 | 0.0329 | 0.0000 | 0.0567 | 0.0000 | 0.1025 | 0.0000 | 0.1459 | 0.0000 | 0.1189 | 0.0000 | 0.1432 | 0.0000 | 0.3765 | 0.0000 | 0.0017 | 0.0028 | 0.0050 | 0.0176 | 0.0419 | 0.0771 | 0.0726 | 0.0997 | 0.6818 | 21 | 32 | 52 | 93 | 142 | 205 | 283 | 380 | 530 | 0.0112 | 32.03 | 6.315 | 0.3897 | 93278.7 | 53900000 | 36900000000 | 28400000000000 | 0.5194 | 0.1468 | 0.0368 | 0.0022 | 0.1715 | 0.0112 | 0.2748 | 0.0782 | 0.1614 | 0.1448 | 0.1334 | 0.1933 | 0.0945 | 0.1853 | 0.0577 | 0.1275 | 0.0408 | 0.1189 | 0.0291 | 0.1384 | 0.0004 | 0.0005 | 0.0011 | 0.0010 | 0.0036 | 0.0028 | 0.0148 | 0.0107 | 0.0581 | 0.0512 | 0.1064 | 0.0873 | 0.0753 | 0.0672 | 0.1096 | 0.0986 | 0.6307 | 0.6805 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0066 | 0.0087 | 0.0278 | 0.0330 | 0.0781 | 0.0932 | 0.1289 | 0.1454 | 0.1017 | 0.1011 | 0.1260 | 0.1267 | 0.5291 | 0.4877 | 0.0007 | 0.0016 | 0.0048 | 0.0183 | 0.0725 | 0.1147 | 0.0880 | 0.1182 | 0.5812 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 563 | 523 | | 7584 | 13597 | 292.9 | 83.06 | 182.75 | 174.84 | 193 | 209 | 226 | 248 | 286 | 322 | 349 | 375 | 408 | 0.0785 | 1067 | 1.101 | 127.77 | 42.45 | 1 | 0.0407 | 309 | 0.0016 | 18.42 | 6.833 | 0.3003 | 92706.4 | 31400000 | 11200000000 | 4180000000000 | 0.4037 | 0.2427 | 0.0029 | 0.0000 | 0.0068 | 0.0012 | 0.0184 | 0.0023 | 0.0417 | 0.0059 | 0.0763 | 0.0230 | 0.1000 | 0.0516 | 0.1051 | 0.0428 | 0.1263 | 0.0614 | 0.5225 | 0.8120 | 0.0010 | 0.0000 | 0.0022 | 0.0011 | 0.0026 | 0.0007 | 0.0070 | 0.0022 | 0.0191 | 0.0112 | 0.0291 | 0.0256 | 0.0275 | 0.0134 | 0.0388 | 0.0299 | 0.8726 | 0.9160 | 0.0014 | 0.0000 | 0.0023 | 0.0000 | 0.0073 | 0.0000 | 0.0200 | 0.0000 | 0.0514 | 0.0000 | 0.0906 | 0.0000 | 0.0915 | 0.0000 | 0.1138 | 0.0000 | 0.6218 | 0.0000 | 0.0000 | 0.0005 | 0.0005 | 0.0055 | 0.0191 | 0.0372 | 0.0372 | 0.0563 | 0.8437 | 21 | 37 | 61 | 91 | 127 | 171 | 226 | 307 | 431 | 0.0098 | 23.73 | 6.012 | 0.4274 | 63963.5 | 31000000 | 18200000000 | 12200000000000 | 0.4970 | 0.1734 | 0.0146 | 0.0008 | 0.0690 | 0.0059 | 0.1458 | 0.0403 | 0.1437 | 0.0687 | 0.1813 | 0.1390 | 0.1557 | 0.1647 | 0.0967 | 0.1352 | 0.0810 | 0.1280 | 0.1123 | 0.3175 | 0.0002 | 0.0000 | 0.0006 | 0.0014 | 0.0034 | 0.0032 | 0.0156 | 0.0128 | 0.0523 | 0.0433 | 0.0827 | 0.0651 | 0.0658 | 0.0553 | 0.0969 | 0.0768 | 0.6825 | 0.7421 | 0.0007 | 0.0011 | 0.0009 | 0.0049 | 0.0082 | 0.0066 | 0.0238 | 0.0255 | 0.0714 | 0.0887 | 0.1100 | 0.1319 | 0.0872 | 0.0887 | 0.1249 | 0.1379 | 0.5728 | 0.5147 | 0.0002 | 0.0029 | 0.0057 | 0.0176 | 0.0629 | 0.0975 | 0.0805 | 0.1129 | 0.6198 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 226 | 604 | | 4693 | 21436 | 383.8 | 76.01 | 185.02 | 221.64 | 284 | 313 | 337 | 360 | 381 | 402 | 425 | 454 | 486 | 0.0416 | 891 | 1.052 | 130.17 | 34.01 | 1 | 0.0641 | 301 | 0.0008 | 47.52 | 7.327 | 0.1592 | 153105.0 | 63300000 | 27000000000 | 11900000000000 | 0.3995 | 0.2470 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0023 | 0.0002 | 0.0165 | 0.0017 | 0.0621 | 0.0177 | 0.1229 | 0.0293 | 0.1371 | 0.0275 | 0.1688 | 0.0446 | 0.4889 | 0.8790 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0073 | 0.0015 | 0.0275 | 0.0148 | 0.0536 | 0.0238 | 0.0573 | 0.0171 | 0.0744 | 0.0278 | 0.7785 | 0.9150 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0156 | 0.0000 | 0.0648 | 0.0000 | 0.1212 | 0.0000 | 0.1633 | 0.0000 | 0.1357 | 0.0000 | 0.1465 | 0.0000 | 0.3409 | 0.0000 | 0.0000 | 0.0009 | 0.0069 | 0.0221 | 0.0711 | 0.1111 | 0.0954 | 0.1176 | 0.5748 | 15 | 18 | 24 | 44 | 80 | 141 | 230 | 343 | 529 | 0.0288 | 19.62 | 5.529 | 0.4998 | 83352.2 | 50500000 | 35500000000 | 27500000000000 | 0.4199 | 0.2507 | 0.0207 | 0.0005 | 0.0995 | 0.0062 | 0.2392 | 0.0328 | 0.2041 | 0.0859 | 0.1593 | 0.1798 | 0.1282 | 0.2251 | 0.0610 | 0.1479 | 0.0518 | 0.1262 | 0.0362 | 0.1956 | 0.0004 | 0.0000 | 0.0006 | 0.0003 | 0.0016 | 0.0010 | 0.0080 | 0.0073 | 0.0421 | 0.0351 | 0.0732 | 0.0620 | 0.0459 | 0.0433 | 0.0727 | 0.0653 | 0.7556 | 0.7856 | 0.0000 | 0.0003 | 0.0009 | 0.0012 | 0.0020 | 0.0024 | 0.0131 | 0.0137 | 0.0524 | 0.0608 | 0.0851 | 0.0996 | 0.0622 | 0.0649 | 0.0907 | 0.0941 | 0.6935 | 0.6629 | 0.0001 | 0.0005 | 0.0023 | 0.0104 | 0.0496 | 0.0769 | 0.0547 | 0.0770 | 0.7284 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 292 | 776 | | 6777 | 12524 | 325.6 | 51.91 | 172.85 | 222.30 | 258 | 277 | 296 | 311 | 323 | 337 | 352 | 369 | 393 | 0.0787 | 986 | 1.019 | 135.34 | 41.01 | 1 | 0.0484 | 328 | 0.0017 | 16.93 | 6.629 | 0.2646 | 108700.0 | 37200000 | 13000000000 | 4670000000000 | 0.3905 | 0.2545 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0036 | 0.0001 | 0.0131 | 0.0003 | 0.0300 | 0.0124 | 0.0571 | 0.0234 | 0.0742 | 0.0142 | 0.0991 | 0.0285 | 0.7210 | 0.9211 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0000 | 0.0071 | 0.0001 | 0.0167 | 0.0114 | 0.0295 | 0.0193 | 0.0326 | 0.0106 | 0.0443 | 0.0171 | 0.8660 | 0.9414 | 0.0057 | 0.0000 | 0.0114 | 0.0000 | 0.0341 | 0.0000 | 0.0994 | 0.0000 | 0.0994 | 0.0000 | 0.1605 | 0.0000 | 0.1179 | 0.0000 | 0.1264 | 0.0000 | 0.3452 | 0.0000 | 0.0015 | 0.0034 | 0.0073 | 0.0208 | 0.0531 | 0.0784 | 0.0815 | 0.1227 | 0.6313 | 14 | 16 | 19 | 25 | 51 | 113 | 215 | 343 | 515 | 0.0450 | 24.78 | 5.251 | 0.4914 | 79286.9 | 49200000 | 36500000000 | 31300000000000 | 0.4891 | 0.1521 | 0.0682 | 0.0006 | 0.2302 | 0.0144 | 0.3264 | 0.1428 | 0.1949 | 0.1888 | 0.1084 | 0.2199 | 0.0560 | 0.1929 | 0.0097 | 0.1180 | 0.0049 | 0.0760 | 0.0012 | 0.0466 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0015 | 0.0099 | 0.0101 | 0.0578 | 0.0482 | 0.0893 | 0.0778 | 0.0562 | 0.0523 | 0.0885 | 0.0782 | 0.6971 | 0.7317 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0023 | 0.0032 | 0.0138 | 0.0193 | 0.0706 | 0.0776 | 0.1115 | 0.1144 | 0.0701 | 0.0761 | 0.0996 | 0.1129 | 0.6310 | 0.5957 | 0.0000 | 0.0000 | 0.0012 | 0.0129 | 0.0628 | 0.1014 | 0.0584 | 0.0960 | 0.6673 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1036 | 656 | | 6909 | 17984 | 410.6 | 89.98 | 149.03 | 156.51 | 291 | 332 | 361 | 387 | 409 | 432 | 457 | 486 | 536 | 0.0622 | 1118 | 0.898 | 69.57 | 17.20 | 1 | 0.0248 | 171 | 0.0008 | 36.78 | 7.401 | 0.1966 | 176674.0 | 79200000 | 36900000000 | 17700000000000 | 0.4312 | 0.2120 | 0.0007 | 0.0000 | 0.0016 | 0.0002 | 0.0034 | 0.0005 | 0.0108 | 0.0020 | 0.0391 | 0.0147 | 0.0913 | 0.0355 | 0.0855 | 0.0290 | 0.1133 | 0.0461 | 0.6543 | 0.8720 | 0.0004 | 0.0000 | 0.0004 | 0.0001 | 0.0025 | 0.0000 | 0.0034 | 0.0009 | 0.0166 | 0.0112 | 0.0378 | 0.0207 | 0.0314 | 0.0124 | 0.0448 | 0.0203 | 0.8629 | 0.9343 | 0.0032 | 0.0000 | 0.0080 | 0.0000 | 0.0135 | 0.0000 | 0.0358 | 0.0000 | 0.0923 | 0.0000 | 0.1146 | 0.0000 | 0.0819 | 0.0000 | 0.1233 | 0.0000 | 0.5274 | 0.0000 | 0.0006 | 0.0024 | 0.0059 | 0.0221 | 0.0489 | 0.0734 | 0.0681 | 0.0943 | 0.6844 | 11 | 14 | 25 | 52 | 91 | 138 | 202 | 281 | 382 | 0.0546 | 17.50 | 5.311 | 0.5113 | 46702.5 | 19100000 | 9060000000 | 4790000000000 | 0.5773 | 0.1082 | 0.0176 | 0.0024 | 0.0828 | 0.0099 | 0.1823 | 0.0387 | 0.1855 | 0.0739 | 0.1780 | 0.1442 | 0.1507 | 0.1991 | 0.0866 | 0.1416 | 0.0663 | 0.1505 | 0.0502 | 0.2396 | 0.0004 | 0.0002 | 0.0013 | 0.0009 | 0.0018 | 0.0020 | 0.0098 | 0.0055 | 0.0367 | 0.0299 | 0.0651 | 0.0490 | 0.0517 | 0.0398 | 0.0765 | 0.0650 | 0.7568 | 0.8077 | 0.0005 | 0.0006 | 0.0005 | 0.0012 | 0.0035 | 0.0038 | 0.0112 | 0.0175 | 0.0539 | 0.0691 | 0.1009 | 0.1110 | 0.0752 | 0.0900 | 0.1122 | 0.1267 | 0.6422 | 0.5802 | 0.0003 | 0.0004 | 0.0029 | 0.0108 | 0.0469 | 0.0779 | 0.0647 | 0.0975 | 0.6985 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 382 | 919 | | 6897 | 11121 | 362.8 | 74.41 | 225.10 | 252.79 | 267 | 298 | 321 | 341 | 358 | 379 | 401 | 427 | 462 | 0.0739 | 822 | 1.086 | 120.93 | 34.41 | 1 | 0.0406 | 280 | 0.0009 | 36.87 | 7.251 | 0.1983 | 137149.0 | 53900000 | 21900000000 | 9220000000000 | 0.4314 | 0.2131 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0005 | 0.0135 | 0.0012 | 0.0506 | 0.0134 | 0.0981 | 0.0302 | 0.1155 | 0.0258 | 0.1361 | 0.0368 | 0.5832 | 0.8921 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0002 | 0.0004 | 0.0061 | 0.0010 | 0.0215 | 0.0104 | 0.0426 | 0.0219 | 0.0481 | 0.0148 | 0.0570 | 0.0214 | 0.8240 | 0.9300 | 0.0050 | 0.0000 | 0.0075 | 0.0000 | 0.0199 | 0.0000 | 0.0489 | 0.0000 | 0.1095 | 0.0000 | 0.1376 | 0.0000 | 0.1086 | 0.0000 | 0.1327 | 0.0000 | 0.4303 | 0.0000 | 0.0003 | 0.0024 | 0.0055 | 0.0240 | 0.0518 | 0.1046 | 0.0888 | 0.1001 | 0.6225 | 16 | 19 | 26 | 60 | 133 | 209 | 292 | 408 | 608 | 0.0252 | 45.18 | 5.945 | 0.4029 | 114568.0 | 77900000 | 62700000000 | 56900000000000 | 0.5295 | 0.1405 | 0.0233 | 0.0008 | 0.1395 | 0.0101 | 0.2197 | 0.0563 | 0.1828 | 0.1049 | 0.1612 | 0.1734 | 0.1275 | 0.1937 | 0.0762 | 0.1418 | 0.0489 | 0.1329 | 0.0209 | 0.1860 | 0.0004 | 0.0002 | 0.0004 | 0.0004 | 0.0021 | 0.0016 | 0.0092 | 0.0085 | 0.0536 | 0.0397 | 0.0929 | 0.0707 | 0.0709 | 0.0541 | 0.1009 | 0.0724 | 0.6695 | 0.7524 | 0.0003 | 0.0010 | 0.0008 | 0.0029 | 0.0058 | 0.0059 | 0.0202 | 0.0280 | 0.0810 | 0.0982 | 0.1221 | 0.1321 | 0.0928 | 0.0956 | 0.1260 | 0.1337 | 0.5510 | 0.5026 | 0.0000 | 0.0010 | 0.0036 | 0.0157 | 0.0703 | 0.1098 | 0.0834 | 0.1150 | 0.6013 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 618 | 706 | | 10617 | 14965 | 406.0 | 74.21 | 106.42 | 146.05 | 301 | 340 | 368 | 390 | 410 | 428 | 446 | 467 | 497 | 0.0708 | 1060 | 1.136 | 84.60 | 28.00 | 1 | 0.0195 | 207 | 0.0009 | 31.67 | 7.285 | 0.2045 | 170377.0 | 73700000 | 32700000000 | 14900000000000 | 0.4237 | 0.2226 | 0.0007 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0002 | 0.0088 | 0.0007 | 0.0302 | 0.0106 | 0.0672 | 0.0224 | 0.0738 | 0.0182 | 0.1228 | 0.0277 | 0.6938 | 0.9203 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0001 | 0.0037 | 0.0004 | 0.0152 | 0.0092 | 0.0270 | 0.0175 | 0.0239 | 0.0109 | 0.0406 | 0.0156 | 0.8882 | 0.9463 | 0.0126 | 0.0000 | 0.0223 | 0.0000 | 0.0334 | 0.0000 | 0.0713 | 0.0000 | 0.1166 | 0.0000 | 0.1308 | 0.0000 | 0.1010 | 0.0000 | 0.1337 | 0.0000 | 0.3782 | 0.0000 | 0.0016 | 0.0018 | 0.0038 | 0.0148 | 0.0460 | 0.0748 | 0.0780 | 0.1090 | 0.6702 | 14 | 17 | 21 | 27 | 38 | 57 | 93 | 167 | 327 | 0.0504 | 11.32 | 4.608 | 0.5968 | 32654.3 | 14800000 | 7870000000 | 4610000000000 | 0.5804 | 0.0982 | 0.0354 | 0.0029 | 0.1407 | 0.0100 | 0.2405 | 0.0716 | 0.1506 | 0.1194 | 0.1370 | 0.1573 | 0.0962 | 0.1935 | 0.0762 | 0.1149 | 0.0681 | 0.1036 | 0.0554 | 0.2268 | 0.0006 | 0.0011 | 0.0011 | 0.0011 | 0.0034 | 0.0037 | 0.0120 | 0.0134 | 0.0582 | 0.0461 | 0.0881 | 0.0767 | 0.0586 | 0.0530 | 0.0837 | 0.0788 | 0.6943 | 0.7262 | 0.0000 | 0.0003 | 0.0011 | 0.0012 | 0.0027 | 0.0049 | 0.0165 | 0.0172 | 0.0692 | 0.0712 | 0.1000 | 0.1157 | 0.0744 | 0.0740 | 0.1085 | 0.1074 | 0.6276 | 0.6080 | 0.0005 | 0.0005 | 0.0019 | 0.0150 | 0.0645 | 0.0978 | 0.0619 | 0.1022 | 0.6557 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 317 | 690 | | 3464 | 11834 | 342.0 | 75.63 | 178.33 | 204.51 | 250 | 275 | 296 | 316 | 334 | 353 | 374 | 407 | 449 | 0.0724 | 857 | 0.954 | 122.41 | 43.14 | 1 | 0.0944 | 327 | 0.0010 | 39.91 | 7.112 | 0.1793 | 122696.0 | 46100000 | 18100000000 | 7380000000000 | 0.3949 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0033 | 0.0000 | 0.0135 | 0.0025 | 0.0652 | 0.0246 | 0.1226 | 0.0467 | 0.1086 | 0.0418 | 0.1407 | 0.0563 | 0.5461 | 0.8278 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0061 | 0.0015 | 0.0275 | 0.0178 | 0.0582 | 0.0338 | 0.0453 | 0.0228 | 0.0735 | 0.0336 | 0.7874 | 0.8906 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0061 | 0.0000 | 0.0350 | 0.0000 | 0.1035 | 0.0000 | 0.1461 | 0.0000 | 0.0989 | 0.0000 | 0.1370 | 0.0000 | 0.4718 | 0.0000 | 0.0006 | 0.0025 | 0.0063 | 0.0151 | 0.0753 | 0.0834 | 0.0997 | 0.1173 | 0.5997 | 15 | 19 | 31 | 55 | 87 | 145 | 230 | 323 | 470 | 0.0227 | 19.50 | 5.564 | 0.4886 | 73621.5 | 41900000 | 28500000000 | 21900000000000 | 0.6117 | 0.0866 | 0.0329 | 0.0009 | 0.1078 | 0.0038 | 0.2187 | 0.0509 | 0.1920 | 0.0937 | 0.1694 | 0.1715 | 0.1283 | 0.2068 | 0.0688 | 0.1413 | 0.0431 | 0.1328 | 0.0390 | 0.1983 | 0.0002 | 0.0002 | 0.0004 | 0.0002 | 0.0017 | 0.0009 | 0.0090 | 0.0061 | 0.0363 | 0.0348 | 0.0722 | 0.0563 | 0.0539 | 0.0445 | 0.0705 | 0.0661 | 0.7557 | 0.7909 | 0.0003 | 0.0006 | 0.0018 | 0.0012 | 0.0021 | 0.0033 | 0.0127 | 0.0169 | 0.0496 | 0.0586 | 0.0939 | 0.1112 | 0.0702 | 0.0843 | 0.0915 | 0.0991 | 0.6779 | 0.6248 | 0.0000 | 0.0007 | 0.0017 | 0.0106 | 0.0439 | 0.0866 | 0.0599 | 0.0792 | 0.7175 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 600 | | 4616 | 7928 | 344.2 | 66.06 | 265.90 | 254.61 | 259 | 286 | 308 | 325 | 341 | 359 | 377 | 401 | 435 | 0.1043 | 827 | 1.180 | 138.18 | 54.34 | 1 | 0.0782 | 361 | 0.0012 | 25.73 | 6.964 | 0.2269 | 122856.0 | 45400000 | 17300000000 | 6770000000000 | 0.4140 | 0.2347 | 0.0009 | 0.0000 | 0.0025 | 0.0002 | 0.0041 | 0.0002 | 0.0173 | 0.0013 | 0.0447 | 0.0183 | 0.0676 | 0.0359 | 0.0711 | 0.0219 | 0.1101 | 0.0415 | 0.6818 | 0.8807 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0007 | 0.0197 | 0.0159 | 0.0277 | 0.0303 | 0.0289 | 0.0135 | 0.0451 | 0.0266 | 0.8668 | 0.9131 | 0.0028 | 0.0000 | 0.0041 | 0.0000 | 0.0180 | 0.0000 | 0.0511 | 0.0000 | 0.0898 | 0.0000 | 0.1367 | 0.0000 | 0.1450 | 0.0000 | 0.1257 | 0.0000 | 0.4268 | 0.0000 | 0.0013 | 0.0031 | 0.0071 | 0.0205 | 0.0361 | 0.0672 | 0.0828 | 0.1033 | 0.6785 | 30 | 47 | 84 | 143 | 199 | 254 | 331 | 426 | 605 | 0.0066 | 47.91 | 6.596 | 0.3097 | 135523.0 | 96800000 | 84600000000 | 83800000000000 | 0.5314 | 0.1336 | 0.0148 | 0.0008 | 0.0818 | 0.0076 | 0.2167 | 0.0239 | 0.1528 | 0.0725 | 0.1730 | 0.1457 | 0.1302 | 0.1803 | 0.1005 | 0.1489 | 0.0733 | 0.1636 | 0.0569 | 0.2568 | 0.0000 | 0.0000 | 0.0011 | 0.0007 | 0.0061 | 0.0013 | 0.0143 | 0.0088 | 0.0586 | 0.0424 | 0.1040 | 0.0805 | 0.0828 | 0.0621 | 0.1157 | 0.0988 | 0.6175 | 0.7053 | 0.0008 | 0.0010 | 0.0016 | 0.0075 | 0.0076 | 0.0139 | 0.0298 | 0.0378 | 0.0953 | 0.0925 | 0.1460 | 0.1492 | 0.0973 | 0.1089 | 0.1375 | 0.1318 | 0.4841 | 0.4575 | 0.0003 | 0.0016 | 0.0046 | 0.0178 | 0.0753 | 0.1358 | 0.0976 | 0.1289 | 0.5381 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 666 | 790 | | 3561 | 6069 | 315.0 | 63.10 | 119.80 | 156.57 | 227 | 261 | 284 | 299 | 314 | 331 | 348 | 367 | 395 | 0.1005 | 610 | 0.944 | 100.02 | 29.00 | 1 | 0.0702 | 250 | 0.0018 | 20.47 | 6.604 | 0.2773 | 103228.0 | 35100000 | 12300000000 | 4460000000000 | 0.4022 | 0.2404 | 0.0004 | 0.0003 | 0.0000 | 0.0003 | 0.0021 | 0.0003 | 0.0141 | 0.0006 | 0.0428 | 0.0204 | 0.0782 | 0.0351 | 0.0669 | 0.0260 | 0.0973 | 0.0348 | 0.6981 | 0.8823 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0007 | 0.0003 | 0.0034 | 0.0003 | 0.0180 | 0.0162 | 0.0312 | 0.0272 | 0.0220 | 0.0139 | 0.0339 | 0.0210 | 0.8904 | 0.9206 | 0.0055 | 0.0000 | 0.0092 | 0.0000 | 0.0295 | 0.0000 | 0.0368 | 0.0000 | 0.0976 | 0.0000 | 0.1860 | 0.0000 | 0.0994 | 0.0000 | 0.1400 | 0.0000 | 0.3959 | 0.0000 | 0.0006 | 0.0011 | 0.0034 | 0.0169 | 0.0410 | 0.0713 | 0.0691 | 0.0871 | 0.7096 | 20 | 26 | 33 | 40 | 50 | 72 | 111 | 174 | 336 | 0.0366 | 13.58 | 4.709 | 0.5959 | 38861.2 | 20100000 | 13000000000 | 9720000000000 | 0.4035 | 0.2191 | 0.0130 | 0.0025 | 0.0681 | 0.0076 | 0.1426 | 0.0245 | 0.1313 | 0.0700 | 0.1361 | 0.1308 | 0.1669 | 0.1975 | 0.1070 | 0.1156 | 0.1216 | 0.1089 | 0.1135 | 0.3426 | 0.0000 | 0.0008 | 0.0005 | 0.0004 | 0.0044 | 0.0012 | 0.0112 | 0.0082 | 0.0486 | 0.0434 | 0.0816 | 0.0643 | 0.0505 | 0.0549 | 0.0802 | 0.0680 | 0.7230 | 0.7588 | 0.0007 | 0.0008 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0160 | 0.0159 | 0.0625 | 0.0700 | 0.1006 | 0.1026 | 0.0569 | 0.0644 | 0.0944 | 0.0907 | 0.6655 | 0.6547 | 0.0000 | 0.0035 | 0.0047 | 0.0135 | 0.0541 | 0.0858 | 0.0553 | 0.0829 | 0.7002 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 792 | 805 | | 4919 | 8206 | 382.1 | 68.91 | 141.31 | 188.12 | 300 | 324 | 344 | 360 | 375 | 392 | 412 | 438 | 476 | 0.0898 | 737 | 1.029 | 141.51 | 47.89 | 1 | 0.0732 | 360 | 0.0011 | 37.46 | 7.089 | 0.1984 | 150764.0 | 61400000 | 25800000000 | 11200000000000 | 0.4301 | 0.2151 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0030 | 0.0000 | 0.0107 | 0.0015 | 0.0411 | 0.0153 | 0.0748 | 0.0283 | 0.0789 | 0.0233 | 0.1114 | 0.0344 | 0.6794 | 0.8971 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0041 | 0.0008 | 0.0202 | 0.0133 | 0.0357 | 0.0198 | 0.0359 | 0.0131 | 0.0538 | 0.0182 | 0.8484 | 0.9348 | 0.0014 | 0.0000 | 0.0043 | 0.0000 | 0.0216 | 0.0000 | 0.0620 | 0.0000 | 0.1037 | 0.0000 | 0.1527 | 0.0000 | 0.1081 | 0.0000 | 0.1326 | 0.0000 | 0.4135 | 0.0000 | 0.0022 | 0.0022 | 0.0118 | 0.0263 | 0.0679 | 0.1121 | 0.0937 | 0.1222 | 0.5617 | 17 | 22 | 29 | 36 | 53 | 94 | 149 | 244 | 370 | 0.0319 | 21.94 | 5.086 | 0.5347 | 55351.4 | 34100000 | 26500000000 | 23500000000000 | 0.4596 | 0.1622 | 0.0237 | 0.0014 | 0.1379 | 0.0121 | 0.2020 | 0.0752 | 0.1323 | 0.1079 | 0.1295 | 0.1526 | 0.1337 | 0.1923 | 0.0975 | 0.1214 | 0.0641 | 0.1008 | 0.0794 | 0.2363 | 0.0000 | 0.0000 | 0.0010 | 0.0003 | 0.0007 | 0.0012 | 0.0104 | 0.0064 | 0.0542 | 0.0436 | 0.0808 | 0.0753 | 0.0636 | 0.0516 | 0.0855 | 0.0680 | 0.7037 | 0.7537 | 0.0013 | 0.0000 | 0.0000 | 0.0010 | 0.0018 | 0.0015 | 0.0075 | 0.0185 | 0.0755 | 0.0713 | 0.1132 | 0.1307 | 0.0644 | 0.0723 | 0.1012 | 0.1142 | 0.6350 | 0.5905 | 0.0004 | 0.0008 | 0.0016 | 0.0117 | 0.0600 | 0.1028 | 0.0631 | 0.0919 | 0.6678 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 274 | 223 | | 6457 | 17021 | 77.3 | 19.26 | 210.94 | 213.95 | 57 | 61 | 66 | 70 | 74 | 78 | 84 | 91 | 103 | 0.0644 | 1096 | 0.843 | 90.43 | 26.17 | 1 | 0.0367 | 237 | 0.0028 | 17.12 | 6.228 | 0.2745 | 6348.3 | 556064 | 52200000 | 5250000000 | 0.4510 | 0.1996 | 0.0010 | 0.0000 | 0.0056 | 0.0003 | 0.0133 | 0.0005 | 0.0380 | 0.0061 | 0.0745 | 0.0225 | 0.1425 | 0.0484 | 0.1711 | 0.0522 | 0.2152 | 0.0849 | 0.3389 | 0.7851 | 0.0004 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0000 | 0.0163 | 0.0020 | 0.0342 | 0.0138 | 0.0671 | 0.0273 | 0.0778 | 0.0218 | 0.1102 | 0.0414 | 0.6848 | 0.8935 | 0.0074 | 0.0130 | 0.0197 | 0.0216 | 0.0303 | 0.0670 | 0.0663 | 0.1058 | 0.1286 | 0.1685 | 0.1335 | 0.1598 | 0.1179 | 0.1102 | 0.1605 | 0.1102 | 0.3358 | 0.2441 | 0.0024 | 0.0094 | 0.0171 | 0.0447 | 0.0765 | 0.1024 | 0.1080 | 0.1279 | 0.5114 | 18 | 30 | 63 | 104 | 145 | 194 | 257 | 356 | 511 | 0.0108 | 28.47 | 6.188 | 0.3938 | 90266.1 | 55800000 | 45300000000 | 46700000000000 | 0.5019 | 0.1685 | 0.0158 | 0.0008 | 0.0801 | 0.0060 | 0.1780 | 0.0286 | 0.1711 | 0.0730 | 0.1885 | 0.1548 | 0.1561 | 0.2064 | 0.0991 | 0.1523 | 0.0752 | 0.1528 | 0.0360 | 0.2253 | 0.0009 | 0.0001 | 0.0013 | 0.0006 | 0.0042 | 0.0030 | 0.0144 | 0.0093 | 0.0568 | 0.0438 | 0.0954 | 0.0772 | 0.0796 | 0.0684 | 0.1057 | 0.0967 | 0.6416 | 0.7008 | 0.0013 | 0.0018 | 0.0031 | 0.0027 | 0.0098 | 0.0098 | 0.0233 | 0.0219 | 0.0729 | 0.0825 | 0.1141 | 0.1324 | 0.0873 | 0.0882 | 0.1187 | 0.1185 | 0.5694 | 0.5421 | 0.0022 | 0.0021 | 0.0062 | 0.0230 | 0.0643 | 0.1045 | 0.0826 | 0.1072 | 0.6079 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1021 | 289 | | 15480 | 20962 | 107.9 | 32.54 | 126.87 | 115.24 | 70 | 80 | 88 | 96 | 104 | 112 | 122 | 133 | 151 | 0.0665 | 1394 | 1.246 | 41.87 | 18.36 | 4 | 0.0075 | 116 | 0.0011 | 32.98 | 7.115 | 0.2122 | 12708.7 | 1630000 | 225000000 | 33600000000 | 0.4430 | 0.2071 | 0.0021 | 0.0002 | 0.0042 | 0.0005 | 0.0146 | 0.0012 | 0.0424 | 0.0071 | 0.1092 | 0.0273 | 0.1709 | 0.0639 | 0.1595 | 0.0673 | 0.1788 | 0.1076 | 0.3183 | 0.7248 | 0.0014 | 0.0002 | 0.0020 | 0.0003 | 0.0039 | 0.0009 | 0.0118 | 0.0037 | 0.0393 | 0.0149 | 0.0650 | 0.0333 | 0.0601 | 0.0290 | 0.0876 | 0.0504 | 0.7289 | 0.8672 | 0.0025 | 0.0080 | 0.0037 | 0.0173 | 0.0202 | 0.0306 | 0.0567 | 0.0766 | 0.1110 | 0.1671 | 0.1514 | 0.1598 | 0.1194 | 0.1152 | 0.1455 | 0.1418 | 0.3896 | 0.2836 | 0.0011 | 0.0021 | 0.0090 | 0.0274 | 0.0627 | 0.1065 | 0.0944 | 0.1225 | 0.5742 | 16 | 27 | 45 | 67 | 94 | 124 | 161 | 212 | 289 | 0.0159 | 8.96 | 5.332 | 0.5036 | 29376.6 | 9390000 | 3750000000 | 1790000000000 | 0.4948 | 0.1572 | 0.0112 | 0.0016 | 0.0613 | 0.0068 | 0.1433 | 0.0245 | 0.1682 | 0.0618 | 0.1919 | 0.1370 | 0.1645 | 0.1771 | 0.1051 | 0.1416 | 0.0836 | 0.1568 | 0.0709 | 0.2928 | 0.0008 | 0.0004 | 0.0011 | 0.0016 | 0.0035 | 0.0026 | 0.0133 | 0.0076 | 0.0489 | 0.0371 | 0.0788 | 0.0577 | 0.0640 | 0.0520 | 0.0930 | 0.0767 | 0.6966 | 0.7643 | 0.0006 | 0.0013 | 0.0028 | 0.0020 | 0.0070 | 0.0071 | 0.0249 | 0.0329 | 0.0705 | 0.0821 | 0.1139 | 0.1305 | 0.0891 | 0.1028 | 0.1163 | 0.1349 | 0.5748 | 0.5065 | 0.0001 | 0.0018 | 0.0055 | 0.0186 | 0.0602 | 0.0898 | 0.0819 | 0.1099 | 0.6321 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 470 | 334 | | 17082 | 34713 | 121.5 | 40.86 | 150.26 | 149.90 | 78 | 87 | 96 | 104 | 113 | 124 | 137 | 153 | 176 | 0.0613 | 2127 | 0.917 | 53.45 | 21.26 | 5 | 0.0091 | 155 | 0.0008 | 47.08 | 7.438 | 0.1848 | 16426.1 | 2470000 | 412000000 | 75400000000 | 0.5115 | 0.1584 | 0.0012 | 0.0001 | 0.0040 | 0.0001 | 0.0120 | 0.0016 | 0.0473 | 0.0092 | 0.1219 | 0.0386 | 0.1808 | 0.0802 | 0.1691 | 0.0807 | 0.1727 | 0.1152 | 0.2911 | 0.6742 | 0.0005 | 0.0001 | 0.0019 | 0.0001 | 0.0033 | 0.0009 | 0.0140 | 0.0056 | 0.0416 | 0.0205 | 0.0689 | 0.0420 | 0.0618 | 0.0336 | 0.0900 | 0.0533 | 0.7179 | 0.8439 | 0.0012 | 0.0043 | 0.0043 | 0.0104 | 0.0127 | 0.0293 | 0.0437 | 0.0804 | 0.1009 | 0.1268 | 0.1386 | 0.1608 | 0.1105 | 0.1154 | 0.1410 | 0.1334 | 0.4469 | 0.3392 | 0.0011 | 0.0023 | 0.0098 | 0.0256 | 0.0655 | 0.1021 | 0.0917 | 0.1081 | 0.5939 | 13 | 20 | 40 | 73 | 109 | 146 | 192 | 255 | 354 | 0.0246 | 17.30 | 5.572 | 0.4804 | 45049.4 | 19600000 | 11700000000 | 9560000000000 | 0.5599 | 0.1198 | 0.0163 | 0.0018 | 0.0736 | 0.0061 | 0.1603 | 0.0328 | 0.1540 | 0.0660 | 0.1820 | 0.1370 | 0.1647 | 0.1862 | 0.1066 | 0.1461 | 0.0830 | 0.1520 | 0.0595 | 0.2718 | 0.0002 | 0.0004 | 0.0015 | 0.0006 | 0.0032 | 0.0019 | 0.0118 | 0.0080 | 0.0480 | 0.0350 | 0.0826 | 0.0652 | 0.0678 | 0.0531 | 0.0929 | 0.0754 | 0.6920 | 0.7604 | 0.0006 | 0.0013 | 0.0019 | 0.0026 | 0.0068 | 0.0081 | 0.0218 | 0.0295 | 0.0745 | 0.0894 | 0.1255 | 0.1446 | 0.0963 | 0.1068 | 0.1258 | 0.1351 | 0.5468 | 0.4826 | 0.0005 | 0.0014 | 0.0039 | 0.0169 | 0.0590 | 0.1040 | 0.0801 | 0.1148 | 0.6194 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1218 | 331 | | 5158 | 11255 | 109.5 | 27.54 | 210.24 | 157.90 | 76 | 87 | 94 | 101 | 107 | 113 | 121 | 132 | 147 | 0.0888 | 999 | 0.982 | 161.79 | 52.24 | 2 | 0.0812 | 419 | 0.0014 | 32.09 | 6.880 | 0.2109 | 12755.0 | 1570000 | 204000000 | 27800000000 | 0.4280 | 0.2240 | 0.0010 | 0.0000 | 0.0046 | 0.0002 | 0.0137 | 0.0020 | 0.0332 | 0.0061 | 0.0853 | 0.0250 | 0.1439 | 0.0581 | 0.1598 | 0.0664 | 0.1960 | 0.0836 | 0.3626 | 0.7585 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0032 | 0.0010 | 0.0112 | 0.0022 | 0.0364 | 0.0170 | 0.0670 | 0.0376 | 0.0687 | 0.0309 | 0.1000 | 0.0426 | 0.7120 | 0.8686 | 0.0096 | 0.0140 | 0.0115 | 0.0197 | 0.0239 | 0.0337 | 0.0822 | 0.1489 | 0.1377 | 0.1601 | 0.1424 | 0.1573 | 0.1243 | 0.1433 | 0.1348 | 0.1180 | 0.3337 | 0.2051 | 0.0038 | 0.0059 | 0.0169 | 0.0418 | 0.0823 | 0.1283 | 0.1177 | 0.1346 | 0.4688 | 46 | 78 | 107 | 136 | 168 | 205 | 255 | 330 | 441 | 0.0032 | 32.72 | 6.476 | 0.3151 | 69130.2 | 29900000 | 15400000000 | 9000000000000 | 0.5329 | 0.1282 | 0.0180 | 0.0007 | 0.0912 | 0.0074 | 0.1973 | 0.0320 | 0.1694 | 0.0776 | 0.1551 | 0.1513 | 0.1470 | 0.1874 | 0.0989 | 0.1477 | 0.0755 | 0.1517 | 0.0476 | 0.2442 | 0.0007 | 0.0003 | 0.0018 | 0.0020 | 0.0065 | 0.0043 | 0.0235 | 0.0156 | 0.0685 | 0.0528 | 0.1185 | 0.0846 | 0.0952 | 0.0742 | 0.1250 | 0.1087 | 0.5602 | 0.6575 | 0.0026 | 0.0033 | 0.0058 | 0.0066 | 0.0151 | 0.0147 | 0.0422 | 0.0518 | 0.1013 | 0.1200 | 0.1487 | 0.1637 | 0.1117 | 0.1076 | 0.1414 | 0.1333 | 0.4312 | 0.3990 | 0.0007 | 0.0057 | 0.0119 | 0.0306 | 0.0952 | 0.1313 | 0.1048 | 0.1375 | 0.4823 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 834 | 433 | | 10028 | 23515 | 170.4 | 45.07 | 251.81 | 223.41 | 116 | 130 | 142 | 154 | 167 | 180 | 195 | 212 | 231 | 0.0643 | 1511 | 0.433 | 138.81 | 20.40 | 4 | 0.0343 | 344 | 0.0006 | 58.13 | 7.696 | 0.1518 | 31076.2 | 6010000 | 1230000000 | 261000000000 | 0.4626 | 0.2012 | 0.0014 | 0.0001 | 0.0014 | 0.0000 | 0.0051 | 0.0010 | 0.0350 | 0.0070 | 0.1108 | 0.0315 | 0.1699 | 0.0658 | 0.1503 | 0.0658 | 0.1738 | 0.0971 | 0.3522 | 0.7316 | 0.0008 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0007 | 0.0127 | 0.0044 | 0.0411 | 0.0206 | 0.0636 | 0.0401 | 0.0541 | 0.0301 | 0.0732 | 0.0469 | 0.7527 | 0.8573 | 0.0016 | 0.0064 | 0.0036 | 0.0242 | 0.0121 | 0.0382 | 0.0395 | 0.1057 | 0.0999 | 0.1643 | 0.1386 | 0.1771 | 0.1185 | 0.1414 | 0.1350 | 0.1210 | 0.4512 | 0.2217 | 0.0013 | 0.0027 | 0.0055 | 0.0224 | 0.0554 | 0.0952 | 0.0829 | 0.1036 | 0.6310 | 27 | 65 | 104 | 142 | 188 | 246 | 318 | 410 | 550 | 0.0043 | 51.61 | 6.756 | 0.3199 | 113315.0 | 70500000 | 54700000000 | 49800000000000 | 0.5106 | 0.1551 | 0.0197 | 0.0009 | 0.0972 | 0.0050 | 0.2185 | 0.0351 | 0.1851 | 0.0833 | 0.1744 | 0.1635 | 0.1413 | 0.2193 | 0.0821 | 0.1599 | 0.0479 | 0.1407 | 0.0337 | 0.1922 | 0.0004 | 0.0003 | 0.0007 | 0.0007 | 0.0030 | 0.0032 | 0.0179 | 0.0117 | 0.0615 | 0.0449 | 0.0961 | 0.0795 | 0.0799 | 0.0637 | 0.0995 | 0.0868 | 0.6409 | 0.7092 | 0.0008 | 0.0013 | 0.0027 | 0.0038 | 0.0078 | 0.0110 | 0.0324 | 0.0428 | 0.0867 | 0.1042 | 0.1373 | 0.1566 | 0.0965 | 0.1074 | 0.1356 | 0.1445 | 0.5003 | 0.4284 | 0.0004 | 0.0017 | 0.0054 | 0.0273 | 0.0740 | 0.1165 | 0.0851 | 0.1169 | 0.5726 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1060 | 312 | | 8531 | 15239 | 406.2 | 51.13 | 226.15 | 245.25 | 342 | 364 | 380 | 392 | 404 | 416 | 431 | 449 | 474 | 0.0668 | 1018 | 0.868 | 57.87 | 17.89 | 1 | 0.0178 | 152 | 0.0013 | 38.37 | 6.954 | 0.1978 | 167626.0 | 70200000 | 29900000000 | 12900000000000 | 0.4561 | 0.1965 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0042 | 0.0000 | 0.0191 | 0.0097 | 0.0469 | 0.0162 | 0.0566 | 0.0088 | 0.0892 | 0.0171 | 0.7825 | 0.9482 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0126 | 0.0097 | 0.0255 | 0.0162 | 0.0268 | 0.0088 | 0.0439 | 0.0152 | 0.8900 | 0.9501 | 0.0146 | 1.0000 | 0.0419 | 0.0000 | 0.0419 | 0.0000 | 0.1129 | 0.0000 | 0.1548 | 0.0000 | 0.1876 | 0.0000 | 0.1220 | 0.0000 | 0.1275 | 0.0000 | 0.1967 | 0.0000 | 0.0026 | 0.0043 | 0.0115 | 0.0412 | 0.0740 | 0.1178 | 0.1135 | 0.1283 | 0.5068 | 15 | 19 | 31 | 68 | 137 | 220 | 311 | 421 | 569 | 0.0214 | 62.72 | 6.209 | 0.3748 | 111286.0 | 74000000 | 60400000000 | 58100000000000 | 0.5099 | 0.1391 | 0.0526 | 0.0022 | 0.1940 | 0.0114 | 0.2544 | 0.1134 | 0.1674 | 0.1438 | 0.1298 | 0.1878 | 0.1032 | 0.1837 | 0.0545 | 0.1188 | 0.0292 | 0.1096 | 0.0149 | 0.1292 | 0.0000 | 0.0001 | 0.0001 | 0.0004 | 0.0007 | 0.0003 | 0.0079 | 0.0047 | 0.0500 | 0.0399 | 0.0844 | 0.0694 | 0.0697 | 0.0522 | 0.1028 | 0.0844 | 0.6841 | 0.7486 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0027 | 0.0049 | 0.0148 | 0.0281 | 0.0769 | 0.0926 | 0.1317 | 0.1530 | 0.1039 | 0.1070 | 0.1377 | 0.1459 | 0.5322 | 0.4672 | 0.0000 | 0.0000 | 0.0020 | 0.0090 | 0.0602 | 0.1073 | 0.0860 | 0.1254 | 0.6102 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |