High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 998 | 485 | | 4473 | 15868 | 223.3 | 42.57 | 170.54 | 190.66 | 167 | 185 | 199 | 211 | 221 | 232 | 244 | 259 | 279 | 0.0531 | 843 | 0.739 | 107.82 | 35.01 | 1 | 0.0722 | 323 | 0.0012 | 31.42 | 6.899 | 0.2014 | 51676.7 | 12400000 | 3060000000 | 781000000000 | 0.4192 | 0.2236 | 0.0016 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0147 | 0.0009 | 0.0482 | 0.0156 | 0.1042 | 0.0328 | 0.1130 | 0.0248 | 0.1586 | 0.0425 | 0.5557 | 0.8834 | 0.0013 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0048 | 0.0002 | 0.0213 | 0.0134 | 0.0435 | 0.0239 | 0.0437 | 0.0125 | 0.0680 | 0.0215 | 0.8155 | 0.9284 | 0.0073 | 0.0174 | 0.0132 | 0.0174 | 0.0323 | 0.0348 | 0.0852 | 0.1826 | 0.1160 | 0.1739 | 0.1880 | 0.2000 | 0.1483 | 0.1217 | 0.1219 | 0.1043 | 0.2878 | 0.1478 | 0.0018 | 0.0050 | 0.0055 | 0.0315 | 0.0721 | 0.1132 | 0.1178 | 0.1251 | 0.5279 | 12 | 17 | 28 | 49 | 86 | 143 | 221 | 333 | 461 | 0.0266 | 31.54 | 5.838 | 0.4485 | 65434.3 | 33400000 | 20100000000 | 13900000000000 | 0.5142 | 0.1765 | 0.0522 | 0.0024 | 0.1949 | 0.0152 | 0.2023 | 0.0988 | 0.1266 | 0.1475 | 0.1199 | 0.1915 | 0.1098 | 0.1664 | 0.0831 | 0.1072 | 0.0522 | 0.0954 | 0.0589 | 0.1756 | 0.0003 | 0.0004 | 0.0003 | 0.0008 | 0.0018 | 0.0008 | 0.0091 | 0.0077 | 0.0519 | 0.0426 | 0.0874 | 0.0779 | 0.0733 | 0.0632 | 0.1020 | 0.0877 | 0.6738 | 0.7190 | 0.0004 | 0.0004 | 0.0014 | 0.0034 | 0.0038 | 0.0054 | 0.0148 | 0.0199 | 0.0648 | 0.0719 | 0.1143 | 0.1171 | 0.0843 | 0.0862 | 0.1204 | 0.1209 | 0.5958 | 0.5749 | 0.0003 | 0.0012 | 0.0037 | 0.0126 | 0.0592 | 0.0980 | 0.0826 | 0.1114 | 0.6309 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 608 | 285 | | 12711 | 40214 | 295.5 | 67.78 | 143.73 | 163.15 | 209 | 239 | 260 | 277 | 293 | 309 | 328 | 350 | 384 | 0.0353 | 1418 | 1.016 | 119.62 | 46.69 | 2 | 0.0271 | 344 | 0.0013 | 26.32 | 6.921 | 0.2277 | 91894.8 | 30000000 | 10200000000 | 3620000000000 | 0.4370 | 0.2187 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0006 | 0.0194 | 0.0020 | 0.0643 | 0.0160 | 0.1388 | 0.0422 | 0.1306 | 0.0429 | 0.1606 | 0.0610 | 0.4809 | 0.8354 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0053 | 0.0011 | 0.0274 | 0.0105 | 0.0590 | 0.0245 | 0.0510 | 0.0194 | 0.0701 | 0.0291 | 0.7861 | 0.9154 | 0.0071 | 0.0128 | 0.0075 | 0.0192 | 0.0179 | 0.0417 | 0.0613 | 0.1330 | 0.1289 | 0.1875 | 0.1811 | 0.2051 | 0.1097 | 0.0865 | 0.1506 | 0.1330 | 0.3358 | 0.1811 | 0.0008 | 0.0024 | 0.0064 | 0.0265 | 0.0750 | 0.1260 | 0.1010 | 0.1299 | 0.5321 | 11 | 17 | 28 | 49 | 80 | 122 | 178 | 254 | 371 | 0.0435 | 17.85 | 5.232 | 0.4864 | 47276.4 | 22300000 | 13100000000 | 8910000000000 | 0.4347 | 0.1843 | 0.0559 | 0.0013 | 0.1725 | 0.0173 | 0.2681 | 0.1183 | 0.1475 | 0.1465 | 0.1431 | 0.1771 | 0.0944 | 0.1809 | 0.0533 | 0.1241 | 0.0376 | 0.1058 | 0.0276 | 0.1288 | 0.0001 | 0.0001 | 0.0004 | 0.0006 | 0.0019 | 0.0015 | 0.0116 | 0.0097 | 0.0649 | 0.0509 | 0.1109 | 0.0898 | 0.0752 | 0.0672 | 0.1098 | 0.0956 | 0.6253 | 0.6846 | 0.0006 | 0.0007 | 0.0011 | 0.0013 | 0.0036 | 0.0075 | 0.0213 | 0.0276 | 0.0840 | 0.0988 | 0.1417 | 0.1531 | 0.0910 | 0.0952 | 0.1254 | 0.1330 | 0.5313 | 0.4828 | 0.0003 | 0.0013 | 0.0032 | 0.0164 | 0.0787 | 0.1225 | 0.0861 | 0.1208 | 0.5707 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 547 | 289 | | 11285 | 27072 | 244.5 | 58.73 | 197.38 | 232.26 | 172 | 193 | 209 | 224 | 239 | 255 | 274 | 296 | 325 | 0.0436 | 1181 | 1.186 | 113.74 | 45.89 | 1 | 0.0262 | 296 | 0.0006 | 59.04 | 7.598 | 0.1608 | 63242.6 | 17200000 | 4920000000 | 1470000000000 | 0.4595 | 0.1977 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0003 | 0.0222 | 0.0030 | 0.0838 | 0.0183 | 0.1665 | 0.0428 | 0.1519 | 0.0447 | 0.1695 | 0.0687 | 0.4015 | 0.8221 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0009 | 0.0000 | 0.0056 | 0.0015 | 0.0329 | 0.0117 | 0.0689 | 0.0232 | 0.0624 | 0.0202 | 0.0836 | 0.0302 | 0.7454 | 0.9132 | 0.0042 | 0.0118 | 0.0042 | 0.0251 | 0.0161 | 0.0340 | 0.0589 | 0.0991 | 0.1158 | 0.1731 | 0.1866 | 0.1864 | 0.1001 | 0.1080 | 0.1387 | 0.1391 | 0.3753 | 0.2234 | 0.0010 | 0.0019 | 0.0079 | 0.0250 | 0.0784 | 0.1238 | 0.0992 | 0.1291 | 0.5338 | 14 | 18 | 26 | 48 | 94 | 162 | 255 | 375 | 541 | 0.0240 | 59.33 | 6.100 | 0.4045 | 92900.8 | 59800000 | 46700000000 | 42500000000000 | 0.3821 | 0.2440 | 0.0415 | 0.0013 | 0.1747 | 0.0119 | 0.3178 | 0.1184 | 0.1407 | 0.1403 | 0.1199 | 0.1896 | 0.0884 | 0.1946 | 0.0465 | 0.1232 | 0.0336 | 0.1013 | 0.0369 | 0.1196 | 0.0001 | 0.0002 | 0.0000 | 0.0003 | 0.0009 | 0.0010 | 0.0080 | 0.0057 | 0.0480 | 0.0394 | 0.0973 | 0.0776 | 0.0603 | 0.0509 | 0.0905 | 0.0756 | 0.6949 | 0.7492 | 0.0002 | 0.0004 | 0.0020 | 0.0014 | 0.0027 | 0.0026 | 0.0159 | 0.0171 | 0.0664 | 0.0775 | 0.1207 | 0.1335 | 0.0813 | 0.0857 | 0.1106 | 0.1232 | 0.6001 | 0.5585 | 0.0001 | 0.0006 | 0.0019 | 0.0122 | 0.0586 | 0.1142 | 0.0705 | 0.1007 | 0.6412 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 683 | 505 | | 9600 | 13298 | 347.1 | 90.75 | 319.79 | 439.11 | 246 | 274 | 294 | 312 | 332 | 353 | 381 | 416 | 470 | 0.0782 | 1040 | 0.961 | 166.08 | 57.22 | 7 | 0.0454 | 436 | 0.0006 | 69.61 | 7.648 | 0.1494 | 128725.0 | 51000000 | 21600000000 | 9760000000000 | 0.4152 | 0.2290 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0044 | 0.0001 | 0.0190 | 0.0018 | 0.0789 | 0.0210 | 0.1597 | 0.0534 | 0.1464 | 0.0539 | 0.1647 | 0.0695 | 0.4253 | 0.8003 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0072 | 0.0008 | 0.0324 | 0.0123 | 0.0692 | 0.0280 | 0.0621 | 0.0217 | 0.0867 | 0.0317 | 0.7404 | 0.9055 | 0.0011 | 0.0013 | 0.0042 | 0.0116 | 0.0116 | 0.0142 | 0.0563 | 0.0927 | 0.1216 | 0.1660 | 0.1689 | 0.1789 | 0.1068 | 0.1042 | 0.1474 | 0.1416 | 0.3821 | 0.2896 | 0.0019 | 0.0036 | 0.0075 | 0.0278 | 0.0824 | 0.1264 | 0.0993 | 0.1177 | 0.5333 | 8 | 11 | 19 | 48 | 133 | 237 | 381 | 574 | 904 | 0.0562 | 65.50 | 5.773 | 0.4645 | 295068.0 | 395000000 | 660000000000 | 1.28E+15 | 0.5123 | 0.1612 | 0.0285 | 0.0008 | 0.1068 | 0.0100 | 0.2304 | 0.0455 | 0.1628 | 0.1039 | 0.1575 | 0.1882 | 0.1495 | 0.1902 | 0.0730 | 0.1302 | 0.0525 | 0.1448 | 0.0391 | 0.1865 | 0.0000 | 0.0000 | 0.0004 | 0.0007 | 0.0014 | 0.0009 | 0.0073 | 0.0049 | 0.0456 | 0.0385 | 0.0721 | 0.0610 | 0.0536 | 0.0421 | 0.0776 | 0.0731 | 0.7421 | 0.7787 | 0.0003 | 0.0009 | 0.0008 | 0.0017 | 0.0015 | 0.0020 | 0.0134 | 0.0187 | 0.0628 | 0.0715 | 0.0953 | 0.1049 | 0.0630 | 0.0729 | 0.0985 | 0.1136 | 0.6646 | 0.6137 | 0.0002 | 0.0011 | 0.0013 | 0.0095 | 0.0546 | 0.0888 | 0.0517 | 0.0893 | 0.7034 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1107 | 725 | | 3073 | 3969 | 338.0 | 79.28 | 111.41 | 132.27 | 234 | 267 | 290 | 314 | 335 | 356 | 378 | 405 | 441 | 0.1217 | 483 | 1.226 | 141.20 | 63.63 | 1 | 0.1276 | 392 | 0.0012 | 36.06 | 6.918 | 0.1908 | 120541.0 | 45200000 | 17700000000 | 7230000000000 | 0.4322 | 0.2106 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0044 | 0.0000 | 0.0183 | 0.0046 | 0.0759 | 0.0201 | 0.1506 | 0.0466 | 0.1440 | 0.0508 | 0.1849 | 0.0756 | 0.4219 | 0.8019 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0017 | 0.0000 | 0.0079 | 0.0033 | 0.0277 | 0.0147 | 0.0513 | 0.0287 | 0.0484 | 0.0184 | 0.0778 | 0.0277 | 0.7854 | 0.9068 | 0.0033 | 0.0248 | 0.0082 | 0.0124 | 0.0131 | 0.0559 | 0.0784 | 0.1801 | 0.1373 | 0.2236 | 0.2124 | 0.1677 | 0.1193 | 0.1242 | 0.1373 | 0.1118 | 0.2909 | 0.0994 | 0.0007 | 0.0013 | 0.0060 | 0.0219 | 0.0672 | 0.1203 | 0.1110 | 0.1356 | 0.5359 | 12 | 23 | 35 | 48 | 64 | 85 | 116 | 178 | 274 | 0.0254 | 11.05 | 4.985 | 0.5393 | 29902.0 | 13200000 | 7610000000 | 5130000000000 | 0.5025 | 0.1307 | 0.0142 | 0.0010 | 0.0548 | 0.0120 | 0.1258 | 0.0239 | 0.1400 | 0.0658 | 0.1826 | 0.1396 | 0.1562 | 0.1854 | 0.1014 | 0.1206 | 0.1055 | 0.1356 | 0.1197 | 0.3161 | 0.0006 | 0.0000 | 0.0000 | 0.0026 | 0.0019 | 0.0036 | 0.0130 | 0.0104 | 0.0467 | 0.0410 | 0.0746 | 0.0607 | 0.0655 | 0.0524 | 0.0966 | 0.0841 | 0.7010 | 0.7451 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0038 | 0.0043 | 0.0076 | 0.0152 | 0.0725 | 0.0769 | 0.0925 | 0.1073 | 0.0620 | 0.0921 | 0.1115 | 0.1138 | 0.6501 | 0.5894 | 0.0024 | 0.0016 | 0.0041 | 0.0114 | 0.0571 | 0.0702 | 0.0637 | 0.0980 | 0.6914 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 318 | 398 | | 21149 | 32393 | 118.4 | 36.13 | 198.09 | 230.96 | 79 | 89 | 97 | 105 | 112 | 121 | 131 | 144 | 166 | 0.0593 | 1920 | 0.736 | 173.25 | 37.64 | 3 | 0.0214 | 452 | 0.0021 | 20.81 | 6.559 | 0.2661 | 15334.3 | 2180000 | 343000000 | 59700000000 | 0.4453 | 0.2046 | 0.0012 | 0.0001 | 0.0027 | 0.0003 | 0.0109 | 0.0011 | 0.0349 | 0.0049 | 0.1040 | 0.0257 | 0.1712 | 0.0574 | 0.1644 | 0.0633 | 0.1813 | 0.0975 | 0.3295 | 0.7498 | 0.0006 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0008 | 0.0116 | 0.0021 | 0.0381 | 0.0130 | 0.0636 | 0.0258 | 0.0677 | 0.0265 | 0.0964 | 0.0418 | 0.7166 | 0.8899 | 0.0030 | 0.0065 | 0.0063 | 0.0145 | 0.0203 | 0.0187 | 0.0586 | 0.0816 | 0.1155 | 0.1493 | 0.1471 | 0.1968 | 0.1274 | 0.1129 | 0.1298 | 0.1399 | 0.3918 | 0.2799 | 0.0020 | 0.0048 | 0.0084 | 0.0315 | 0.0770 | 0.1122 | 0.0985 | 0.1278 | 0.5378 | 14 | 17 | 25 | 48 | 96 | 167 | 259 | 373 | 535 | 0.0276 | 93.42 | 6.409 | 0.3746 | 92580.9 | 58500000 | 44100000000 | 37800000000000 | 0.5719 | 0.1057 | 0.0647 | 0.0020 | 0.2147 | 0.0220 | 0.2542 | 0.1155 | 0.1479 | 0.1648 | 0.1256 | 0.1968 | 0.0936 | 0.1670 | 0.0523 | 0.1282 | 0.0303 | 0.0948 | 0.0169 | 0.1089 | 0.0004 | 0.0002 | 0.0013 | 0.0011 | 0.0026 | 0.0022 | 0.0119 | 0.0095 | 0.0574 | 0.0487 | 0.0985 | 0.0827 | 0.0773 | 0.0653 | 0.1116 | 0.0939 | 0.6390 | 0.6965 | 0.0004 | 0.0003 | 0.0016 | 0.0021 | 0.0053 | 0.0067 | 0.0183 | 0.0246 | 0.0756 | 0.0872 | 0.1236 | 0.1318 | 0.0932 | 0.1017 | 0.1281 | 0.1345 | 0.5539 | 0.5111 | 0.0007 | 0.0017 | 0.0031 | 0.0149 | 0.0664 | 0.1128 | 0.0859 | 0.1198 | 0.5947 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 996 | 371 | | 11089 | 20661 | 128.1 | 44.85 | 133.68 | 162.62 | 71 | 85 | 99 | 115 | 127 | 138 | 151 | 166 | 188 | 0.0798 | 1648 | 0.895 | 64.56 | 20.03 | 5 | 0.0157 | 174 | 0.0018 | 12.86 | 6.621 | 0.3191 | 18415.0 | 2900000 | 491000000 | 88000000000 | 0.4803 | 0.1576 | 0.0011 | 0.0006 | 0.0045 | 0.0016 | 0.0117 | 0.0035 | 0.0293 | 0.0084 | 0.0819 | 0.0379 | 0.1359 | 0.0583 | 0.1247 | 0.0644 | 0.1531 | 0.0930 | 0.4578 | 0.7323 | 0.0005 | 0.0003 | 0.0015 | 0.0006 | 0.0021 | 0.0017 | 0.0042 | 0.0037 | 0.0222 | 0.0194 | 0.0351 | 0.0255 | 0.0297 | 0.0272 | 0.0482 | 0.0398 | 0.8566 | 0.8816 | 0.0019 | 0.0046 | 0.0038 | 0.0046 | 0.0118 | 0.0178 | 0.0290 | 0.0462 | 0.0667 | 0.1116 | 0.1062 | 0.1155 | 0.0871 | 0.1063 | 0.1161 | 0.1373 | 0.5774 | 0.4561 | 0.0020 | 0.0040 | 0.0047 | 0.0125 | 0.0360 | 0.0599 | 0.0579 | 0.0894 | 0.7335 | 14 | 19 | 29 | 48 | 73 | 107 | 151 | 215 | 335 | 0.0199 | 22.80 | 5.542 | 0.4729 | 44312.1 | 23700000 | 16900000000 | 14500000000000 | 0.5483 | 0.1240 | 0.0154 | 0.0018 | 0.0718 | 0.0095 | 0.1644 | 0.0294 | 0.1714 | 0.0676 | 0.1731 | 0.1375 | 0.1619 | 0.1889 | 0.0967 | 0.1393 | 0.0751 | 0.1444 | 0.0702 | 0.2815 | 0.0008 | 0.0004 | 0.0017 | 0.0019 | 0.0035 | 0.0031 | 0.0174 | 0.0115 | 0.0505 | 0.0433 | 0.0835 | 0.0717 | 0.0604 | 0.0502 | 0.0852 | 0.0807 | 0.6968 | 0.7370 | 0.0015 | 0.0010 | 0.0051 | 0.0020 | 0.0056 | 0.0073 | 0.0197 | 0.0275 | 0.0672 | 0.0761 | 0.1032 | 0.1073 | 0.0716 | 0.0804 | 0.1082 | 0.1177 | 0.6178 | 0.5806 | 0.0010 | 0.0039 | 0.0055 | 0.0211 | 0.0524 | 0.0978 | 0.0670 | 0.0986 | 0.6527 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1041 | 916 | | 403 | 1181 | 80.5 | 10.16 | 173.50 | 253.63 | 67 | 70 | 74 | 77 | 80 | 84 | 86 | 90 | 94 | 0.2320 | 274 | 1.030 | 30.08 | 8.00 | 0 | 0.1762 | 71 | 0.1226 | 0.50 | 2.391 | 0.7876 | 6578.3 | 546175 | 46000000 | 3940000000 | 0.3807 | 0.2394 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0188 | 0.0124 | 0.0591 | 0.0422 | 0.1237 | 0.1166 | 0.1022 | 0.0422 | 0.1532 | 0.0794 | 0.5376 | 0.7072 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0176 | 0.0124 | 0.0403 | 0.0422 | 0.1159 | 0.1166 | 0.0554 | 0.0422 | 0.0781 | 0.0794 | 0.6902 | 0.7072 | 0.0800 | 0.0000 | 0.0800 | 0.0000 | 0.0000 | 0.0000 | 0.2000 | 0.0000 | 0.1200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0048 | 0.0000 | 0.0144 | 0.0383 | 0.1005 | 0.1340 | 0.0861 | 0.1627 | 0.4593 | 19 | 27 | 36 | 48 | 66 | 100 | 161 | 254 | 474 | 0.0380 | 54.53 | 4.632 | 0.4971 | 94375.3 | 84600000 | 95200000000 | 121000000000000 | 0.4414 | 0.1907 | 0.1038 | 0.0045 | 0.2264 | 0.0588 | 0.2170 | 0.1810 | 0.0472 | 0.1267 | 0.1415 | 0.2262 | 0.1321 | 0.1765 | 0.0943 | 0.0679 | 0.0189 | 0.0498 | 0.0189 | 0.1086 | 0.0000 | 0.0000 | 0.0026 | 0.0021 | 0.0026 | 0.0043 | 0.0490 | 0.0322 | 0.1108 | 0.1052 | 0.2010 | 0.1824 | 0.1031 | 0.0966 | 0.1237 | 0.1223 | 0.4072 | 0.4549 | 0.0035 | 0.0041 | 0.0142 | 0.0122 | 0.0284 | 0.0245 | 0.0674 | 0.0531 | 0.1418 | 0.1633 | 0.1596 | 0.1633 | 0.0887 | 0.0939 | 0.1348 | 0.1347 | 0.3617 | 0.3510 | 0.0030 | 0.0030 | 0.0119 | 0.0625 | 0.1310 | 0.1964 | 0.0923 | 0.1190 | 0.3810 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1142 | 279 | | 6081 | 12680 | 333.3 | 75.05 | 132.72 | 150.99 | 244 | 268 | 287 | 305 | 325 | 343 | 366 | 393 | 433 | 0.0758 | 961 | 1.101 | 113.36 | 37.12 | 1 | 0.0462 | 281 | 0.0013 | 26.51 | 6.910 | 0.2088 | 116744.0 | 43000000 | 16600000000 | 6710000000000 | 0.3801 | 0.2654 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0042 | 0.0000 | 0.0168 | 0.0011 | 0.0633 | 0.0200 | 0.1116 | 0.0341 | 0.1355 | 0.0320 | 0.1721 | 0.0541 | 0.4938 | 0.8587 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0020 | 0.0000 | 0.0071 | 0.0005 | 0.0310 | 0.0141 | 0.0482 | 0.0230 | 0.0586 | 0.0181 | 0.0796 | 0.0318 | 0.7721 | 0.9125 | 0.0037 | 0.0088 | 0.0119 | 0.0117 | 0.0165 | 0.0263 | 0.0567 | 0.0380 | 0.1033 | 0.1082 | 0.1435 | 0.1345 | 0.1060 | 0.0936 | 0.1389 | 0.1082 | 0.4196 | 0.4708 | 0.0018 | 0.0043 | 0.0093 | 0.0205 | 0.0751 | 0.1053 | 0.0830 | 0.1165 | 0.5841 | 10 | 15 | 26 | 48 | 77 | 111 | 158 | 228 | 346 | 0.0156 | 26.28 | 5.931 | 0.4048 | 40411.4 | 17400000 | 9060000000 | 5290000000000 | 0.5025 | 0.1413 | 0.0228 | 0.0017 | 0.0773 | 0.0063 | 0.1471 | 0.0370 | 0.1547 | 0.0783 | 0.1747 | 0.1540 | 0.1485 | 0.1778 | 0.1105 | 0.1249 | 0.0905 | 0.1378 | 0.0739 | 0.2822 | 0.0000 | 0.0006 | 0.0013 | 0.0013 | 0.0013 | 0.0021 | 0.0136 | 0.0091 | 0.0417 | 0.0414 | 0.0724 | 0.0662 | 0.0582 | 0.0462 | 0.0751 | 0.0721 | 0.7364 | 0.7610 | 0.0003 | 0.0006 | 0.0021 | 0.0031 | 0.0040 | 0.0037 | 0.0143 | 0.0131 | 0.0562 | 0.0601 | 0.0816 | 0.1055 | 0.0776 | 0.0812 | 0.1052 | 0.1173 | 0.6588 | 0.6153 | 0.0014 | 0.0020 | 0.0034 | 0.0108 | 0.0473 | 0.0756 | 0.0567 | 0.0882 | 0.7146 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1074 | 767 | | 4851 | 8558 | 206.5 | 55.00 | 108.27 | 109.37 | 139 | 160 | 174 | 187 | 202 | 217 | 232 | 251 | 282 | 0.1187 | 1016 | 0.484 | 105.59 | 20.81 | 4 | 0.0662 | 321 | 0.0008 | 57.36 | 7.309 | 0.1587 | 45680.7 | 10800000 | 2680000000 | 703000000000 | 0.4637 | 0.1868 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0086 | 0.0009 | 0.0413 | 0.0069 | 0.0994 | 0.0313 | 0.1640 | 0.0778 | 0.1659 | 0.0680 | 0.1872 | 0.1041 | 0.3321 | 0.7110 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0019 | 0.0006 | 0.0119 | 0.0039 | 0.0380 | 0.0199 | 0.0697 | 0.0448 | 0.0629 | 0.0307 | 0.0941 | 0.0474 | 0.7209 | 0.8527 | 0.0078 | 0.0123 | 0.0059 | 0.0123 | 0.0157 | 0.0567 | 0.0793 | 0.0961 | 0.1360 | 0.1995 | 0.1634 | 0.1847 | 0.1164 | 0.1059 | 0.1585 | 0.1256 | 0.3170 | 0.2069 | 0.0000 | 0.0013 | 0.0048 | 0.0255 | 0.0867 | 0.1175 | 0.1122 | 0.1373 | 0.5147 | 12 | 18 | 29 | 47 | 69 | 99 | 134 | 187 | 268 | 0.0244 | 13.32 | 5.257 | 0.4878 | 23683.4 | 7140000 | 2580000000 | 1050000000000 | 0.5580 | 0.1201 | 0.0405 | 0.0014 | 0.1364 | 0.0151 | 0.1957 | 0.0713 | 0.2286 | 0.1138 | 0.1722 | 0.1731 | 0.1091 | 0.2097 | 0.0640 | 0.1398 | 0.0301 | 0.1316 | 0.0235 | 0.1444 | 0.0008 | 0.0007 | 0.0029 | 0.0009 | 0.0080 | 0.0059 | 0.0252 | 0.0204 | 0.0707 | 0.0557 | 0.1162 | 0.1042 | 0.0849 | 0.0847 | 0.1154 | 0.1074 | 0.5760 | 0.6202 | 0.0007 | 0.0027 | 0.0045 | 0.0063 | 0.0142 | 0.0144 | 0.0359 | 0.0395 | 0.0864 | 0.0997 | 0.1253 | 0.1307 | 0.1029 | 0.1150 | 0.1377 | 0.1370 | 0.4923 | 0.4546 | 0.0019 | 0.0031 | 0.0084 | 0.0273 | 0.0769 | 0.1256 | 0.0924 | 0.1293 | 0.5352 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 352 | 145 | | 6842 | 23190 | 516.1 | 88.93 | 82.73 | 76.82 | 394 | 442 | 473 | 497 | 519 | 540 | 560 | 588 | 626 | 0.0471 | 1092 | 1.217 | 112.40 | 44.05 | 1 | 0.0417 | 285 | 0.0008 | 51.79 | 7.367 | 0.1654 | 274282.0 | 150000000 | 83800000000 | 48000000000000 | 0.4133 | 0.2357 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0068 | 0.0009 | 0.0395 | 0.0128 | 0.0867 | 0.0244 | 0.0880 | 0.0204 | 0.1257 | 0.0318 | 0.6515 | 0.9098 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0001 | 0.0219 | 0.0112 | 0.0469 | 0.0212 | 0.0429 | 0.0121 | 0.0560 | 0.0240 | 0.8305 | 0.9315 | 0.0064 | 0.0000 | 0.0244 | 0.0385 | 0.0450 | 0.1538 | 0.0720 | 0.1795 | 0.1362 | 0.1538 | 0.1542 | 0.1923 | 0.1105 | 0.1538 | 0.1041 | 0.0769 | 0.3470 | 0.0513 | 0.0006 | 0.0014 | 0.0071 | 0.0246 | 0.0801 | 0.1194 | 0.1251 | 0.1398 | 0.5020 | 13 | 21 | 33 | 47 | 63 | 80 | 100 | 127 | 174 | 0.0136 | 7.65 | 5.221 | 0.4945 | 12746.0 | 3030000 | 998000000 | 416000000000 | 0.4776 | 0.1511 | 0.0127 | 0.0009 | 0.0661 | 0.0029 | 0.1634 | 0.0253 | 0.1896 | 0.0621 | 0.2119 | 0.1354 | 0.1531 | 0.1850 | 0.1031 | 0.1644 | 0.0654 | 0.1703 | 0.0348 | 0.2537 | 0.0006 | 0.0001 | 0.0017 | 0.0006 | 0.0053 | 0.0027 | 0.0178 | 0.0129 | 0.0589 | 0.0423 | 0.0902 | 0.0637 | 0.0775 | 0.0651 | 0.1124 | 0.0898 | 0.6356 | 0.7229 | 0.0024 | 0.0026 | 0.0024 | 0.0051 | 0.0088 | 0.0130 | 0.0336 | 0.0403 | 0.0825 | 0.0987 | 0.1329 | 0.1479 | 0.1037 | 0.1076 | 0.1323 | 0.1377 | 0.5013 | 0.4472 | 0.0009 | 0.0038 | 0.0065 | 0.0246 | 0.0676 | 0.1127 | 0.0949 | 0.1192 | 0.5699 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 426 | 374 | | 4318 | 14420 | 143.7 | 34.49 | 119.50 | 125.97 | 103 | 114 | 123 | 131 | 140 | 148 | 158 | 170 | 188 | 0.0620 | 894 | 1.020 | 115.11 | 27.29 | 1 | 0.0602 | 260 | 0.0019 | 27.37 | 6.560 | 0.2321 | 21832.7 | 3510000 | 599000000 | 108000000000 | 0.4264 | 0.2220 | 0.0004 | 0.0000 | 0.0035 | 0.0005 | 0.0196 | 0.0012 | 0.0369 | 0.0027 | 0.0914 | 0.0222 | 0.1656 | 0.0530 | 0.1672 | 0.0527 | 0.1770 | 0.0782 | 0.3383 | 0.7894 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0000 | 0.0113 | 0.0014 | 0.0416 | 0.0148 | 0.0794 | 0.0319 | 0.0708 | 0.0195 | 0.1002 | 0.0380 | 0.6908 | 0.8945 | 0.0049 | 0.0114 | 0.0160 | 0.0114 | 0.0294 | 0.0456 | 0.0896 | 0.1787 | 0.1521 | 0.2129 | 0.1816 | 0.2053 | 0.1411 | 0.0913 | 0.1546 | 0.1293 | 0.2307 | 0.1141 | 0.0005 | 0.0031 | 0.0112 | 0.0386 | 0.0910 | 0.1352 | 0.1256 | 0.1546 | 0.4403 | 17 | 24 | 35 | 47 | 65 | 91 | 142 | 211 | 313 | 0.0080 | 38.15 | 6.234 | 0.3884 | 30147.3 | 10600000 | 4400000000 | 2040000000000 | 0.5107 | 0.1394 | 0.0427 | 0.0034 | 0.1280 | 0.0141 | 0.2110 | 0.0584 | 0.1420 | 0.1202 | 0.1528 | 0.1742 | 0.1412 | 0.1803 | 0.1009 | 0.1302 | 0.0559 | 0.1289 | 0.0256 | 0.1903 | 0.0007 | 0.0013 | 0.0025 | 0.0025 | 0.0054 | 0.0058 | 0.0116 | 0.0120 | 0.0497 | 0.0465 | 0.0797 | 0.0690 | 0.0606 | 0.0582 | 0.0869 | 0.0833 | 0.7029 | 0.7214 | 0.0002 | 0.0008 | 0.0009 | 0.0008 | 0.0044 | 0.0074 | 0.0114 | 0.0183 | 0.0634 | 0.0731 | 0.0992 | 0.1123 | 0.0727 | 0.0847 | 0.1113 | 0.1107 | 0.6365 | 0.5920 | 0.0004 | 0.0021 | 0.0035 | 0.0136 | 0.0496 | 0.0910 | 0.0683 | 0.0899 | 0.6816 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 130 | | 6472 | 11634 | 104.2 | 26.74 | 134.36 | 144.55 | 75 | 82 | 88 | 93 | 99 | 106 | 114 | 124 | 140 | 0.0675 | 785 | 1.222 | 77.80 | 31.00 | 1 | 0.0311 | 201 | 0.0033 | 14.98 | 6.074 | 0.2909 | 11575.5 | 1380000 | 176000000 | 24100000000 | 0.4404 | 0.2109 | 0.0008 | 0.0000 | 0.0067 | 0.0000 | 0.0180 | 0.0003 | 0.0355 | 0.0049 | 0.0968 | 0.0225 | 0.1552 | 0.0473 | 0.1791 | 0.0458 | 0.2071 | 0.0729 | 0.3007 | 0.8063 | 0.0002 | 0.0000 | 0.0028 | 0.0000 | 0.0058 | 0.0002 | 0.0154 | 0.0008 | 0.0436 | 0.0128 | 0.0690 | 0.0233 | 0.0790 | 0.0166 | 0.1135 | 0.0378 | 0.6708 | 0.9086 | 0.0078 | 0.0060 | 0.0132 | 0.0302 | 0.0296 | 0.0302 | 0.0685 | 0.0867 | 0.1401 | 0.1512 | 0.1556 | 0.2198 | 0.1222 | 0.1109 | 0.1362 | 0.1431 | 0.3268 | 0.2218 | 0.0014 | 0.0074 | 0.0159 | 0.0337 | 0.0708 | 0.1173 | 0.1045 | 0.1399 | 0.5090 | 11 | 17 | 27 | 47 | 80 | 123 | 170 | 236 | 349 | 0.0095 | 68.36 | 6.495 | 0.3320 | 38946.3 | 15400000 | 7190000000 | 3780000000000 | 0.5106 | 0.1580 | 0.0359 | 0.0011 | 0.1272 | 0.0129 | 0.2289 | 0.0620 | 0.1945 | 0.1073 | 0.1660 | 0.1675 | 0.1137 | 0.2080 | 0.0666 | 0.1442 | 0.0449 | 0.1357 | 0.0224 | 0.1612 | 0.0002 | 0.0000 | 0.0004 | 0.0005 | 0.0036 | 0.0015 | 0.0120 | 0.0079 | 0.0557 | 0.0459 | 0.0946 | 0.0834 | 0.0802 | 0.0594 | 0.1058 | 0.0943 | 0.6476 | 0.7070 | 0.0003 | 0.0013 | 0.0024 | 0.0032 | 0.0089 | 0.0084 | 0.0282 | 0.0316 | 0.0805 | 0.0832 | 0.1194 | 0.1342 | 0.0982 | 0.1048 | 0.1210 | 0.1303 | 0.5413 | 0.5031 | 0.0002 | 0.0014 | 0.0041 | 0.0182 | 0.0668 | 0.1165 | 0.0832 | 0.1178 | 0.5918 | ||
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 487 | 388 | | 17803 | 45389 | 157.0 | 50.28 | 154.36 | 177.24 | 92 | 114 | 128 | 142 | 155 | 168 | 183 | 200 | 225 | 0.0425 | 1928 | 1.251 | 24.52 | 7.81 | 5 | 0.0033 | 58 | 0.0011 | 27.12 | 7.140 | 0.2383 | 27189.4 | 5090000 | 1010000000 | 213000000000 | 0.4282 | 0.2106 | 0.0016 | 0.0001 | 0.0027 | 0.0011 | 0.0080 | 0.0022 | 0.0288 | 0.0083 | 0.0923 | 0.0292 | 0.1552 | 0.0530 | 0.1536 | 0.0615 | 0.1813 | 0.0892 | 0.3764 | 0.7554 | 0.0006 | 0.0001 | 0.0008 | 0.0008 | 0.0020 | 0.0012 | 0.0062 | 0.0038 | 0.0238 | 0.0118 | 0.0466 | 0.0193 | 0.0520 | 0.0202 | 0.0673 | 0.0299 | 0.8006 | 0.9130 | 0.0028 | 0.0076 | 0.0051 | 0.0076 | 0.0145 | 0.0286 | 0.0373 | 0.0753 | 0.0821 | 0.1201 | 0.1345 | 0.1711 | 0.1117 | 0.1287 | 0.1381 | 0.1368 | 0.4740 | 0.3241 | 0.0009 | 0.0019 | 0.0057 | 0.0186 | 0.0505 | 0.0897 | 0.0859 | 0.1121 | 0.6346 | 13 | 18 | 26 | 47 | 81 | 128 | 193 | 278 | 407 | 0.0395 | 20.75 | 5.394 | 0.5005 | 55240.7 | 27700000 | 16900000000 | 11900000000000 | 0.4247 | 0.2143 | 0.0378 | 0.0014 | 0.1492 | 0.0110 | 0.2622 | 0.0683 | 0.1893 | 0.1171 | 0.1504 | 0.1913 | 0.1095 | 0.1978 | 0.0586 | 0.1383 | 0.0341 | 0.1296 | 0.0088 | 0.1451 | 0.0003 | 0.0002 | 0.0011 | 0.0008 | 0.0022 | 0.0018 | 0.0130 | 0.0095 | 0.0518 | 0.0406 | 0.0919 | 0.0720 | 0.0661 | 0.0535 | 0.0987 | 0.0822 | 0.6750 | 0.7394 | 0.0006 | 0.0006 | 0.0012 | 0.0024 | 0.0051 | 0.0080 | 0.0184 | 0.0254 | 0.0735 | 0.0834 | 0.1248 | 0.1314 | 0.0862 | 0.0949 | 0.1190 | 0.1284 | 0.5712 | 0.5254 | 0.0004 | 0.0015 | 0.0030 | 0.0169 | 0.0596 | 0.1071 | 0.0813 | 0.1092 | 0.6210 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 457 | 212 | | 6322 | 18147 | 382.8 | 44.78 | 238.77 | 294.82 | 326 | 348 | 362 | 373 | 384 | 395 | 406 | 419 | 439 | 0.0600 | 1088 | 1.215 | 99.36 | 36.50 | 1 | 0.0386 | 244 | 0.0018 | 29.68 | 6.658 | 0.2214 | 148564.0 | 58400000 | 23200000000 | 9350000000000 | 0.4200 | 0.2268 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0033 | 0.0005 | 0.0198 | 0.0108 | 0.0385 | 0.0209 | 0.0480 | 0.0104 | 0.0811 | 0.0223 | 0.8084 | 0.9351 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0015 | 0.0005 | 0.0136 | 0.0108 | 0.0260 | 0.0209 | 0.0246 | 0.0104 | 0.0395 | 0.0223 | 0.8947 | 0.9351 | 0.0536 | 0.0000 | 0.0421 | 0.0000 | 0.0651 | 0.0000 | 0.1303 | 0.0000 | 0.1418 | 0.0000 | 0.2222 | 0.0000 | 0.1188 | 0.0000 | 0.1341 | 0.0000 | 0.0920 | 0.0000 | 0.0012 | 0.0049 | 0.0132 | 0.0292 | 0.0679 | 0.1075 | 0.1161 | 0.1588 | 0.5012 | 17 | 22 | 29 | 46 | 89 | 180 | 301 | 457 | 675 | 0.0295 | 57.83 | 5.943 | 0.4328 | 143927.0 | 117000000 | 112000000000 | 121000000000000 | 0.4463 | 0.1845 | 0.0546 | 0.0038 | 0.1914 | 0.0093 | 0.2906 | 0.1053 | 0.1701 | 0.1693 | 0.1184 | 0.2109 | 0.1042 | 0.1922 | 0.0475 | 0.1153 | 0.0156 | 0.0952 | 0.0078 | 0.0987 | 0.0001 | 0.0005 | 0.0011 | 0.0005 | 0.0034 | 0.0014 | 0.0108 | 0.0082 | 0.0532 | 0.0501 | 0.0872 | 0.0742 | 0.0606 | 0.0519 | 0.0872 | 0.0802 | 0.6963 | 0.7330 | 0.0005 | 0.0004 | 0.0021 | 0.0008 | 0.0042 | 0.0052 | 0.0150 | 0.0185 | 0.0656 | 0.0707 | 0.1028 | 0.1137 | 0.0807 | 0.0882 | 0.1081 | 0.1140 | 0.6208 | 0.5885 | 0.0002 | 0.0016 | 0.0046 | 0.0142 | 0.0602 | 0.0943 | 0.0678 | 0.0986 | 0.6586 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 364 | | 5225 | 12570 | 114.6 | 29.24 | 148.81 | 175.19 | 84 | 92 | 98 | 104 | 110 | 116 | 124 | 134 | 151 | 0.0699 | 879 | 0.810 | 72.24 | 18.44 | 1 | 0.0389 | 203 | 0.0030 | 17.44 | 6.162 | 0.2786 | 13983.3 | 1830000 | 261000000 | 40800000000 | 0.4284 | 0.2226 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0091 | 0.0002 | 0.0324 | 0.0035 | 0.0800 | 0.0215 | 0.1378 | 0.0503 | 0.1584 | 0.0530 | 0.2021 | 0.0722 | 0.3790 | 0.7993 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0024 | 0.0000 | 0.0124 | 0.0006 | 0.0398 | 0.0144 | 0.0640 | 0.0290 | 0.0688 | 0.0226 | 0.1076 | 0.0342 | 0.7040 | 0.8992 | 0.0056 | 0.0087 | 0.0111 | 0.0173 | 0.0356 | 0.0376 | 0.0934 | 0.1272 | 0.1446 | 0.1821 | 0.1758 | 0.1792 | 0.1224 | 0.1098 | 0.1313 | 0.1156 | 0.2803 | 0.2225 | 0.0027 | 0.0045 | 0.0145 | 0.0377 | 0.0921 | 0.1403 | 0.1135 | 0.1589 | 0.4358 | 11 | 15 | 26 | 46 | 79 | 124 | 182 | 256 | 391 | 0.0134 | 67.23 | 6.423 | 0.3671 | 52832.2 | 26600000 | 16100000000 | 11000000000000 | 0.5002 | 0.1902 | 0.0463 | 0.0026 | 0.1259 | 0.0198 | 0.2117 | 0.0847 | 0.1593 | 0.1067 | 0.1464 | 0.1418 | 0.1017 | 0.1687 | 0.1017 | 0.1354 | 0.0637 | 0.1313 | 0.0432 | 0.2090 | 0.0002 | 0.0000 | 0.0006 | 0.0005 | 0.0035 | 0.0017 | 0.0186 | 0.0129 | 0.0574 | 0.0525 | 0.0893 | 0.0815 | 0.0763 | 0.0603 | 0.1007 | 0.0887 | 0.6535 | 0.7020 | 0.0005 | 0.0012 | 0.0052 | 0.0030 | 0.0073 | 0.0094 | 0.0250 | 0.0301 | 0.0725 | 0.0779 | 0.1207 | 0.1181 | 0.0816 | 0.0907 | 0.1035 | 0.1026 | 0.5837 | 0.5670 | 0.0000 | 0.0011 | 0.0045 | 0.0194 | 0.0690 | 0.1067 | 0.0853 | 0.1053 | 0.6087 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1055 | 275 | | 6493 | 11263 | 218.6 | 48.26 | 203.76 | 248.93 | 160 | 175 | 188 | 202 | 213 | 228 | 242 | 260 | 284 | 0.0805 | 907 | 1.214 | 109.13 | 46.40 | 1 | 0.0445 | 289 | 0.0010 | 41.92 | 7.174 | 0.1818 | 50116.4 | 12000000 | 3010000000 | 787000000000 | 0.4497 | 0.2024 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0071 | 0.0008 | 0.0185 | 0.0023 | 0.0843 | 0.0181 | 0.1430 | 0.0392 | 0.1440 | 0.0382 | 0.1793 | 0.0581 | 0.4215 | 0.8433 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0033 | 0.0006 | 0.0078 | 0.0012 | 0.0341 | 0.0120 | 0.0614 | 0.0246 | 0.0581 | 0.0156 | 0.0872 | 0.0283 | 0.7468 | 0.9177 | 0.0041 | 0.0101 | 0.0139 | 0.0270 | 0.0204 | 0.0642 | 0.0736 | 0.1182 | 0.1177 | 0.1959 | 0.1586 | 0.1791 | 0.1267 | 0.1115 | 0.1415 | 0.1149 | 0.3434 | 0.1791 | 0.0013 | 0.0037 | 0.0043 | 0.0266 | 0.0817 | 0.1116 | 0.0986 | 0.1305 | 0.5418 | 15 | 19 | 27 | 46 | 82 | 147 | 253 | 388 | 594 | 0.0226 | 54.69 | 5.986 | 0.4245 | 103479.0 | 70800000 | 56800000000 | 51000000000000 | 0.5176 | 0.1383 | 0.0392 | 0.0017 | 0.1105 | 0.0111 | 0.2280 | 0.0589 | 0.2245 | 0.1100 | 0.1425 | 0.1800 | 0.1140 | 0.2156 | 0.0784 | 0.1367 | 0.0439 | 0.1144 | 0.0190 | 0.1717 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0016 | 0.0012 | 0.0128 | 0.0072 | 0.0372 | 0.0364 | 0.0763 | 0.0706 | 0.0547 | 0.0455 | 0.0772 | 0.0701 | 0.7402 | 0.7678 | 0.0006 | 0.0007 | 0.0006 | 0.0000 | 0.0020 | 0.0030 | 0.0121 | 0.0115 | 0.0506 | 0.0603 | 0.0917 | 0.1121 | 0.0697 | 0.0752 | 0.0975 | 0.1124 | 0.6752 | 0.6248 | 0.0000 | 0.0005 | 0.0018 | 0.0083 | 0.0458 | 0.0871 | 0.0564 | 0.0843 | 0.7159 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 825 | 684 | | 7651 | 20186 | 434.9 | 80.92 | 100.21 | 97.16 | 337 | 366 | 390 | 409 | 429 | 448 | 471 | 501 | 545 | 0.0502 | 1013 | 1.138 | 102.84 | 33.06 | 1 | 0.0322 | 246 | 0.0009 | 43.02 | 7.234 | 0.1788 | 195716.0 | 91000000 | 43700000000 | 21700000000000 | 0.4528 | 0.2044 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0003 | 0.0109 | 0.0004 | 0.0464 | 0.0156 | 0.1085 | 0.0248 | 0.1193 | 0.0267 | 0.1502 | 0.0416 | 0.5632 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0047 | 0.0004 | 0.0241 | 0.0132 | 0.0533 | 0.0176 | 0.0554 | 0.0141 | 0.0757 | 0.0217 | 0.7862 | 0.9330 | 0.0026 | 0.0221 | 0.0123 | 0.0608 | 0.0202 | 0.0663 | 0.0792 | 0.1381 | 0.1206 | 0.1547 | 0.1637 | 0.1381 | 0.1021 | 0.1105 | 0.1144 | 0.1050 | 0.3847 | 0.2044 | 0.0011 | 0.0050 | 0.0089 | 0.0319 | 0.0727 | 0.1248 | 0.1040 | 0.1262 | 0.5255 | 9 | 12 | 22 | 46 | 73 | 101 | 133 | 177 | 238 | 0.0261 | 11.79 | 5.435 | 0.4724 | 19482.1 | 5010000 | 1530000000 | 533000000000 | 0.4602 | 0.1900 | 0.0169 | 0.0009 | 0.0928 | 0.0052 | 0.1893 | 0.0424 | 0.1626 | 0.0894 | 0.1630 | 0.1492 | 0.1587 | 0.1861 | 0.0954 | 0.1402 | 0.0745 | 0.1464 | 0.0468 | 0.2402 | 0.0006 | 0.0001 | 0.0007 | 0.0006 | 0.0017 | 0.0015 | 0.0093 | 0.0072 | 0.0425 | 0.0340 | 0.0820 | 0.0612 | 0.0679 | 0.0521 | 0.0976 | 0.0811 | 0.6977 | 0.7621 | 0.0009 | 0.0007 | 0.0013 | 0.0023 | 0.0028 | 0.0042 | 0.0180 | 0.0214 | 0.0688 | 0.0820 | 0.1143 | 0.1324 | 0.0930 | 0.0958 | 0.1199 | 0.1291 | 0.5810 | 0.5321 | 0.0007 | 0.0011 | 0.0034 | 0.0138 | 0.0527 | 0.0963 | 0.0820 | 0.1141 | 0.6359 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1179 | 189 | | 16382 | 26563 | 119.9 | 50.77 | 96.33 | 96.08 | 57 | 80 | 93 | 105 | 115 | 128 | 142 | 159 | 186 | 0.0652 | 1732 | 0.279 | 134.45 | 18.44 | 8 | 0.0245 | 401 | 0.0012 | 34.16 | 7.111 | 0.2279 | 16954.2 | 2720000 | 485000000 | 94900000000 | 0.4885 | 0.1704 | 0.0014 | 0.0001 | 0.0069 | 0.0005 | 0.0266 | 0.0024 | 0.0715 | 0.0104 | 0.1597 | 0.0480 | 0.2113 | 0.0993 | 0.1753 | 0.1092 | 0.1597 | 0.1428 | 0.1876 | 0.5873 | 0.0004 | 0.0001 | 0.0017 | 0.0003 | 0.0033 | 0.0012 | 0.0102 | 0.0037 | 0.0386 | 0.0208 | 0.0699 | 0.0357 | 0.0674 | 0.0386 | 0.0962 | 0.0530 | 0.7123 | 0.8467 | 0.0017 | 0.0038 | 0.0051 | 0.0091 | 0.0110 | 0.0152 | 0.0442 | 0.0800 | 0.1188 | 0.1523 | 0.1512 | 0.1789 | 0.1184 | 0.1144 | 0.1491 | 0.1413 | 0.4006 | 0.3050 | 0.0009 | 0.0013 | 0.0058 | 0.0245 | 0.0728 | 0.1185 | 0.1037 | 0.1302 | 0.5422 | 15 | 22 | 32 | 46 | 64 | 86 | 117 | 158 | 222 | 0.0165 | 11.29 | 5.277 | 0.4716 | 18511.3 | 5390000 | 2090000000 | 994000000000 | 0.5640 | 0.1104 | 0.0416 | 0.0021 | 0.1298 | 0.0145 | 0.2417 | 0.0717 | 0.1786 | 0.1322 | 0.1563 | 0.1705 | 0.1056 | 0.1818 | 0.0805 | 0.1400 | 0.0452 | 0.1272 | 0.0207 | 0.1600 | 0.0013 | 0.0006 | 0.0026 | 0.0025 | 0.0052 | 0.0043 | 0.0226 | 0.0158 | 0.0717 | 0.0537 | 0.1141 | 0.0969 | 0.0904 | 0.0786 | 0.1320 | 0.1170 | 0.5601 | 0.6307 | 0.0017 | 0.0015 | 0.0030 | 0.0031 | 0.0089 | 0.0133 | 0.0324 | 0.0402 | 0.0970 | 0.1132 | 0.1484 | 0.1592 | 0.1051 | 0.1113 | 0.1413 | 0.1490 | 0.4622 | 0.4093 | 0.0015 | 0.0038 | 0.0079 | 0.0238 | 0.0829 | 0.1287 | 0.1026 | 0.1362 | 0.5125 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1195 | 448 | | 4077 | 9038 | 310.9 | 53.86 | 181.75 | 300.58 | 243 | 263 | 279 | 292 | 306 | 323 | 341 | 360 | 384 | 0.0823 | 744 | 0.923 | 64.47 | 17.49 | 1 | 0.0373 | 152 | 0.0015 | 24.49 | 6.739 | 0.2284 | 99584.3 | 32800000 | 11100000000 | 3850000000000 | 0.4223 | 0.2256 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0002 | 0.0166 | 0.0005 | 0.0445 | 0.0156 | 0.0831 | 0.0297 | 0.0950 | 0.0225 | 0.1292 | 0.0312 | 0.6276 | 0.9002 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0014 | 0.0002 | 0.0081 | 0.0005 | 0.0209 | 0.0152 | 0.0345 | 0.0258 | 0.0376 | 0.0142 | 0.0585 | 0.0219 | 0.8387 | 0.9222 | 0.0069 | 0.0000 | 0.0086 | 0.0000 | 0.0293 | 0.0000 | 0.0810 | 0.0000 | 0.1207 | 0.0000 | 0.1828 | 0.0000 | 0.1293 | 0.0000 | 0.1483 | 0.0000 | 0.2931 | 0.0000 | 0.0026 | 0.0021 | 0.0057 | 0.0188 | 0.0490 | 0.0834 | 0.0870 | 0.1021 | 0.6493 | 19 | 24 | 31 | 45 | 71 | 99 | 135 | 242 | 489 | 0.0344 | 32.85 | 5.199 | 0.5254 | 123371.0 | 146000000 | 217000000000 | 363000000000000 | 0.4937 | 0.1466 | 0.0515 | 0.0058 | 0.1530 | 0.0187 | 0.2641 | 0.0515 | 0.1578 | 0.1120 | 0.1401 | 0.1552 | 0.1014 | 0.1964 | 0.0354 | 0.1365 | 0.0290 | 0.1223 | 0.0676 | 0.2015 | 0.0012 | 0.0021 | 0.0063 | 0.0021 | 0.0067 | 0.0027 | 0.0185 | 0.0209 | 0.0653 | 0.0581 | 0.1034 | 0.0877 | 0.0594 | 0.0714 | 0.0975 | 0.1025 | 0.6418 | 0.6525 | 0.0005 | 0.0000 | 0.0010 | 0.0023 | 0.0031 | 0.0029 | 0.0166 | 0.0165 | 0.0786 | 0.0764 | 0.0994 | 0.1107 | 0.0708 | 0.0696 | 0.1124 | 0.1095 | 0.6176 | 0.6121 | 0.0000 | 0.0014 | 0.0023 | 0.0148 | 0.0696 | 0.1035 | 0.0650 | 0.1072 | 0.6362 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1169 | 718 | | 3803 | 6960 | 84.4 | 20.56 | 84.20 | 75.35 | 60 | 68 | 73 | 77 | 82 | 88 | 94 | 101 | 111 | 0.1295 | 901 | 1.055 | 100.65 | 36.80 | 3 | 0.0702 | 267 | 0.0048 | 9.98 | 5.662 | 0.3488 | 7539.7 | 712809 | 71300000 | 7550000000 | 0.4461 | 0.2010 | 0.0035 | 0.0000 | 0.0035 | 0.0006 | 0.0133 | 0.0014 | 0.0434 | 0.0049 | 0.1018 | 0.0301 | 0.1540 | 0.0703 | 0.1717 | 0.0627 | 0.1965 | 0.1162 | 0.3124 | 0.7138 | 0.0007 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0008 | 0.0141 | 0.0025 | 0.0434 | 0.0234 | 0.0736 | 0.0485 | 0.0696 | 0.0294 | 0.0923 | 0.0539 | 0.7024 | 0.8412 | 0.0038 | 0.0423 | 0.0153 | 0.0329 | 0.0204 | 0.0798 | 0.1008 | 0.1596 | 0.1288 | 0.1831 | 0.1760 | 0.2019 | 0.1492 | 0.1221 | 0.1620 | 0.0845 | 0.2436 | 0.0939 | 0.0016 | 0.0066 | 0.0131 | 0.0334 | 0.0826 | 0.1067 | 0.1100 | 0.1379 | 0.5082 | 21 | 29 | 36 | 45 | 57 | 72 | 93 | 129 | 196 | 0.0215 | 6.08 | 4.792 | 0.5469 | 12767.1 | 2810000 | 768000000 | 242000000000 | 0.5949 | 0.1190 | 0.0236 | 0.0027 | 0.0754 | 0.0155 | 0.1471 | 0.0354 | 0.1680 | 0.0787 | 0.1916 | 0.1437 | 0.1471 | 0.1641 | 0.1235 | 0.1433 | 0.0836 | 0.1636 | 0.0400 | 0.2530 | 0.0027 | 0.0010 | 0.0061 | 0.0052 | 0.0097 | 0.0081 | 0.0289 | 0.0240 | 0.0729 | 0.0672 | 0.1069 | 0.0930 | 0.0901 | 0.0750 | 0.1103 | 0.1066 | 0.5724 | 0.6198 | 0.0048 | 0.0038 | 0.0112 | 0.0038 | 0.0117 | 0.0102 | 0.0363 | 0.0326 | 0.0811 | 0.0856 | 0.1323 | 0.1475 | 0.0961 | 0.0958 | 0.1126 | 0.1315 | 0.5139 | 0.4891 | 0.0013 | 0.0093 | 0.0160 | 0.0388 | 0.0835 | 0.1210 | 0.0923 | 0.1151 | 0.5228 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 968 | 97 | | 4897 | 1372 | 105.7 | 28.33 | 79.73 | 69.69 | 76 | 82 | 88 | 94 | 100 | 107 | 114 | 125 | 145 | 0.3797 | 521 | 0.626 | 127.78 | 26.91 | 1 | 0.0764 | 374 | 0.0037 | 15.12 | 6.016 | 0.3192 | 11982.1 | 1460000 | 194000000 | 27700000000 | 0.4561 | 0.1953 | 0.0004 | 0.0000 | 0.0056 | 0.0005 | 0.0215 | 0.0032 | 0.0318 | 0.0068 | 0.0787 | 0.0290 | 0.1126 | 0.0432 | 0.1242 | 0.0375 | 0.1958 | 0.0681 | 0.4294 | 0.8118 | 0.0000 | 0.0000 | 0.0016 | 0.0004 | 0.0081 | 0.0004 | 0.0118 | 0.0016 | 0.0430 | 0.0150 | 0.0568 | 0.0214 | 0.0627 | 0.0183 | 0.1052 | 0.0342 | 0.7108 | 0.9086 | 0.0068 | 0.0046 | 0.0136 | 0.0068 | 0.0340 | 0.0114 | 0.0498 | 0.0683 | 0.1053 | 0.1663 | 0.1268 | 0.2005 | 0.1031 | 0.1435 | 0.1291 | 0.1344 | 0.4315 | 0.2642 | 0.0049 | 0.0049 | 0.0147 | 0.0339 | 0.0776 | 0.1036 | 0.1046 | 0.1297 | 0.5260 | 14 | 20 | 34 | 45 | 59 | 78 | 97 | 125 | 177 | 0.0145 | 15.01 | 5.234 | 0.4127 | 11210.5 | 2240000 | 575000000 | 180000000000 | 0.5721 | 0.0938 | 0.0633 | 0.0085 | 0.1629 | 0.0277 | 0.2081 | 0.1043 | 0.1448 | 0.1447 | 0.1357 | 0.1936 | 0.1222 | 0.1723 | 0.0950 | 0.1191 | 0.0317 | 0.1064 | 0.0362 | 0.1234 | 0.0061 | 0.0013 | 0.0076 | 0.0088 | 0.0244 | 0.0175 | 0.0809 | 0.0489 | 0.1481 | 0.1529 | 0.1664 | 0.1867 | 0.1405 | 0.1291 | 0.1145 | 0.1291 | 0.3115 | 0.3258 | 0.0069 | 0.0061 | 0.0253 | 0.0457 | 0.0346 | 0.0640 | 0.1152 | 0.0854 | 0.1843 | 0.1829 | 0.1797 | 0.1707 | 0.1267 | 0.1646 | 0.1221 | 0.1311 | 0.2051 | 0.1494 | 0.0019 | 0.0168 | 0.0243 | 0.0935 | 0.1832 | 0.1664 | 0.1383 | 0.1421 | 0.2336 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 706 | 476 | | 728 | 1022 | 96.1 | 32.97 | 217.29 | 252.33 | 64 | 70 | 76 | 81 | 87 | 93 | 104 | 119 | 143 | 0.2652 | 271 | 0.410 | 145.45 | 41.40 | 1 | 0.7843 | 571 | 0.0039 | 22.73 | 5.781 | 0.2516 | 10321.1 | 1250000 | 169000000 | 25300000000 | 0.4351 | 0.2119 | 0.0000 | 0.0000 | 0.0173 | 0.0066 | 0.0202 | 0.0099 | 0.0980 | 0.0066 | 0.2161 | 0.0724 | 0.2017 | 0.0938 | 0.2017 | 0.0674 | 0.1441 | 0.1628 | 0.1009 | 0.5806 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0296 | 0.0029 | 0.1006 | 0.0471 | 0.1381 | 0.0799 | 0.1282 | 0.0428 | 0.1440 | 0.1084 | 0.4576 | 0.7190 | 0.0000 | 0.0215 | 0.0000 | 0.0000 | 0.0375 | 0.0000 | 0.0625 | 0.0753 | 0.1438 | 0.1183 | 0.1563 | 0.1720 | 0.1063 | 0.2151 | 0.1438 | 0.1398 | 0.3500 | 0.2581 | 0.0037 | 0.0000 | 0.0112 | 0.0669 | 0.1227 | 0.1450 | 0.0558 | 0.1004 | 0.4944 | 18 | 22 | 28 | 45 | 88 | 168 | 297 | 431 | 602 | 0.0497 | 49.53 | 4.975 | 0.4355 | 110822.0 | 73200000 | 55400000000 | 45800000000000 | 0.5813 | 0.0827 | 0.1029 | 0.0000 | 0.2500 | 0.0581 | 0.3971 | 0.1806 | 0.1324 | 0.2581 | 0.0735 | 0.2387 | 0.0147 | 0.1355 | 0.0294 | 0.0774 | 0.0000 | 0.0387 | 0.0000 | 0.0129 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0074 | 0.0022 | 0.0074 | 0.0285 | 0.0695 | 0.0724 | 0.1390 | 0.1162 | 0.0893 | 0.0943 | 0.1216 | 0.1250 | 0.5608 | 0.5592 | 0.0000 | 0.0000 | 0.0000 | 0.0033 | 0.0090 | 0.0000 | 0.0090 | 0.0233 | 0.0746 | 0.0731 | 0.1731 | 0.1728 | 0.0836 | 0.1163 | 0.1313 | 0.1262 | 0.5194 | 0.4851 | 0.0000 | 0.0000 | 0.0028 | 0.0110 | 0.0579 | 0.1818 | 0.0661 | 0.1350 | 0.5455 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 425 | 155 | | 10526 | 21020 | 318.4 | 61.96 | 206.32 | 250.19 | 242 | 266 | 284 | 299 | 314 | 330 | 347 | 369 | 404 | 0.0516 | 1084 | 1.093 | 105.19 | 36.12 | 1 | 0.0249 | 262 | 0.0006 | 81.62 | 7.746 | 0.1363 | 105224.0 | 36000000 | 12800000000 | 4660000000000 | 0.4431 | 0.2108 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0026 | 0.0000 | 0.0134 | 0.0015 | 0.0534 | 0.0127 | 0.1190 | 0.0291 | 0.1293 | 0.0329 | 0.1742 | 0.0536 | 0.5079 | 0.8701 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0007 | 0.0233 | 0.0087 | 0.0553 | 0.0181 | 0.0559 | 0.0145 | 0.0879 | 0.0257 | 0.7716 | 0.9324 | 0.0047 | 0.0280 | 0.0142 | 0.0592 | 0.0272 | 0.0592 | 0.0781 | 0.1526 | 0.1230 | 0.2087 | 0.1715 | 0.2150 | 0.1212 | 0.1277 | 0.1467 | 0.0779 | 0.3134 | 0.0717 | 0.0012 | 0.0020 | 0.0075 | 0.0315 | 0.0817 | 0.1365 | 0.1121 | 0.1303 | 0.4971 | 16 | 20 | 26 | 45 | 90 | 165 | 257 | 379 | 569 | 0.0265 | 51.36 | 6.104 | 0.4177 | 105162.0 | 74300000 | 63500000000 | 62100000000000 | 0.4677 | 0.1545 | 0.0348 | 0.0018 | 0.1515 | 0.0098 | 0.2413 | 0.0665 | 0.1600 | 0.1355 | 0.1658 | 0.1909 | 0.1109 | 0.1899 | 0.0702 | 0.1368 | 0.0428 | 0.1209 | 0.0227 | 0.1479 | 0.0001 | 0.0002 | 0.0006 | 0.0006 | 0.0021 | 0.0007 | 0.0075 | 0.0067 | 0.0513 | 0.0425 | 0.0842 | 0.0699 | 0.0615 | 0.0534 | 0.0927 | 0.0778 | 0.7001 | 0.7481 | 0.0000 | 0.0002 | 0.0017 | 0.0024 | 0.0040 | 0.0065 | 0.0161 | 0.0168 | 0.0672 | 0.0746 | 0.1113 | 0.1207 | 0.0727 | 0.0793 | 0.1113 | 0.1116 | 0.6157 | 0.5879 | 0.0003 | 0.0009 | 0.0029 | 0.0128 | 0.0565 | 0.0983 | 0.0684 | 0.1010 | 0.6588 |