LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 7 of 15: Mean cell count and mean growth rate across all replicates. - Dataset (ID:20243)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Relative Growth Rate Standard Error of the Mean for Relative Growth Rate
MCF 10A Selumetinib
10.0
uM
LJP6
 0.1692 0.0507 0.0813 0.0261
MCF 10A Sirolimus
10.0
uM
LJP6
 0.9742 0.0767 0.9754 0.0870
MCF 10A Sorafenib
10.0
uM
LJP6
 0.5256 0.0549 0.4742 0.0590
MCF 10A SU11274
10.0
uM
LJP5
 0.3494 0.0627 0.2824 0.0464
MCF 10A Fedratinib
10.0
uM
LJP5
 0.1178 0.0402 0.0235 0.0127
MCF 10A TGX221
10.0
uM
LJP5
 0.9115 0.0868 0.9068 0.0913
MCF 10A Torin1
10.0
uM
LJP6
 0.1288 0.0297 0.0349 0.0021
MCF 10A Torin2
10.0
uM
LJP5
 0.1066 0.0315 0.0103 0.0112
MCF 10A Tozasertib
10.0
uM
LJP5
 0.1184 0.0223 0.0228 0.0087
MCF 10A Trametinib
10.0
uM
LJP5
 0.1955 0.0590 0.1112 0.0363
MCF 10A TWS119
10.0
uM
LJP5
 0.1148 0.0440 0.0204 0.0172
MCF 10A Vemurafenib
10.0
uM
LJP5
 0.3460 0.0839 0.2796 0.0702
MCF 10A Withaferin A
10.0
uM
LJP5
 0.0379 0.0092 -0.0684 0.0400
MCF 10A Withaferin A
10.0
uM
LJP6
 0.0357 0.0096 -0.0710 0.0418
MCF 10A WYE-125132
10.0
uM
LJP6
 0.1508 0.0435 0.0604 0.0179
MCF 10A WZ3105
10.0
uM
LJP5
 0.0338 0.0095 -0.0731 0.0409
MCF 10A XMD11-50
10.0
uM
LJP6
 0.1436 0.0430 0.0523 0.0198
MCF 10A Y39983
10.0
uM
LJP6
 0.2689 0.0859 0.1916 0.0818
MCF 10A YM 201636
10.0
uM
LJP5
 0.2321 0.0522 0.1511 0.0314
MCF 10A ZSTK474
10.0
uM
LJP6
 0.1671 0.0414 0.0782 0.0218
MCF7 Afatinib
0.04
uM
LJP6
 0.7926 0.0621 0.7116 0.0891
MCF7 Sigma A6730
0.04
uM
LJP5
 0.8015 0.0157 0.7252 0.0165
MCF7 Alvocidib
0.04
uM
LJP6
 0.2411 0.0386 -0.0556 0.0706
MCF7 AT-7519
0.04
uM
LJP6
 0.7441 0.1649 0.6379 0.2350
MCF7 AZD 5438
0.04
uM
LJP6
 0.8071 0.0496 0.7306 0.0727